CN107922971A - 用于富集核酸群体的组合物和方法 - Google Patents
用于富集核酸群体的组合物和方法 Download PDFInfo
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- CN107922971A CN107922971A CN201680042387.4A CN201680042387A CN107922971A CN 107922971 A CN107922971 A CN 107922971A CN 201680042387 A CN201680042387 A CN 201680042387A CN 107922971 A CN107922971 A CN 107922971A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/161—Modifications characterised by incorporating target specific and non-target specific sites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/159—Reduction of complexity, e.g. amplification of subsets, removing duplicated genomic regions
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562163273P | 2015-05-18 | 2015-05-18 | |
| US62/163,273 | 2015-05-18 | ||
| US201662334348P | 2016-05-10 | 2016-05-10 | |
| US62/334,348 | 2016-05-10 | ||
| PCT/US2016/032936 WO2016187234A1 (en) | 2015-05-18 | 2016-05-17 | Compositions and methods for enriching populations of nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107922971A true CN107922971A (zh) | 2018-04-17 |
Family
ID=57320699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680042387.4A Pending CN107922971A (zh) | 2015-05-18 | 2016-05-17 | 用于富集核酸群体的组合物和方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11111520B2 (https=) |
| EP (2) | EP3298169B1 (https=) |
| JP (3) | JP6873921B2 (https=) |
| CN (1) | CN107922971A (https=) |
| AU (1) | AU2016264102A1 (https=) |
| BR (1) | BR112017024747A2 (https=) |
| CA (1) | CA2986036C (https=) |
| IL (1) | IL255647B (https=) |
| WO (1) | WO2016187234A1 (https=) |
| ZA (1) | ZA201708264B (https=) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109355365A (zh) * | 2018-11-25 | 2019-02-19 | 中国农业科学院兰州兽医研究所 | 一种小rna高通量测序检测微生物的方法 |
| CN111239392A (zh) * | 2020-02-26 | 2020-06-05 | 浙江诺迦生物科技有限公司 | 一种新型冠状病毒肺炎(covid-19)血清学诊断试剂盒 |
| CN111254190A (zh) * | 2020-01-20 | 2020-06-09 | 中国医学科学院病原生物学研究所 | 一种血浆病毒组学的纳米孔三代测序检测方法 |
| WO2020118543A1 (zh) * | 2018-12-12 | 2020-06-18 | 深圳华大生命科学研究院 | 分离和/或富集宿主源核酸和病原核酸的方法和试剂及其制备方法 |
| CN112888791A (zh) * | 2019-04-29 | 2021-06-01 | 伊鲁米那股份有限公司 | 通过快速温育和核酸富集来鉴定和分析微生物样本 |
| CN113201599A (zh) * | 2021-06-03 | 2021-08-03 | 北京大学人民医院 | 一种基于PCR和nanopore测序检测脑脊液感染哪些病原体的方法 |
| CN113454218A (zh) * | 2018-12-20 | 2021-09-28 | 夸登特健康公司 | 用于改进核酸分子的回收的方法、组合物和系统 |
| CN115786548A (zh) * | 2022-09-29 | 2023-03-14 | 武汉明德生物科技股份有限公司 | 用于病原微生物耐药基因检测的引物组、试剂盒及方法 |
| CN115786547A (zh) * | 2022-09-29 | 2023-03-14 | 武汉明德生物科技股份有限公司 | 用于病原微生物检测的引物组、试剂盒及其应用方法 |
| CN115917002A (zh) * | 2020-04-06 | 2023-04-04 | 奥科坦特公司 | 病原体诊断测试 |
| CN118165982A (zh) * | 2024-04-17 | 2024-06-11 | 上海麦克林生化科技股份有限公司 | Rna快速提取试剂盒及其应用 |
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| CA2971444A1 (en) | 2014-12-20 | 2016-06-23 | Arc Bio, Llc | Compositions and methods for targeted depletion, enrichment, and partitioning of nucleic acids using crispr/cas system proteins |
| CN107922971A (zh) | 2015-05-18 | 2018-04-17 | 凯锐思公司 | 用于富集核酸群体的组合物和方法 |
| AU2016308283B2 (en) | 2015-08-19 | 2022-04-21 | Arc Bio, Llc | Capture of nucleic acids using a nucleic acid-guided nuclease-based system |
| EP3377654B1 (en) | 2015-11-16 | 2024-01-31 | Revere Biosensors, LLC | Systems and methods for identifying and distinguishing genetic samples |
| CA3185611A1 (en) | 2016-03-25 | 2017-09-28 | Karius, Inc. | Synthetic nucleic acid spike-ins |
| GB2559319B (en) * | 2016-12-23 | 2019-01-16 | Cs Genetics Ltd | Reagents and methods for the analysis of linked nucleic acids |
| WO2018119399A1 (en) | 2016-12-23 | 2018-06-28 | Grail, Inc. | Methods for high efficiency library preparation using double-stranded adapters |
| WO2018140452A1 (en) | 2017-01-30 | 2018-08-02 | Counsyl, Inc. | Enrichment of cell-free dna from a biological sample |
| US11155805B2 (en) | 2017-03-27 | 2021-10-26 | Sekisui Medical Co., Ltd. | Target nucleic acid concentration and recovery method using antibody |
| US11274344B2 (en) | 2017-03-30 | 2022-03-15 | Grail, Inc. | Enhanced ligation in sequencing library preparation |
| WO2018183897A1 (en) * | 2017-03-31 | 2018-10-04 | Grail, Inc. | Higher target capture efficiency using probe extension |
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| WO2018195951A1 (en) * | 2017-04-28 | 2018-11-01 | Coyote Diagnostics Lab (Beijing) Co., Ltd. | Integrated sample collection, processing and analysis systems |
| CN110869512A (zh) * | 2017-05-09 | 2020-03-06 | 雷瑞生物传感器有限责任公司 | 鉴别并区分遗传样品的系统及方法 |
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| CN108220479B (zh) * | 2018-01-05 | 2021-08-13 | 浙江农林大学 | 能检测多种猪猝死症病原的多重连接探针扩增鉴别试剂盒 |
| CN110272984A (zh) * | 2018-03-13 | 2019-09-24 | 深圳华大生命科学研究院 | 测序获取寄生虫核酸信息及对寄生虫分类的方法和系统 |
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| ES3059710T3 (en) | 2018-11-21 | 2026-03-23 | Karius Inc | Direct-to-library methods, systems, and compositions |
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| JP7132100B2 (ja) * | 2018-11-21 | 2022-09-06 | 株式会社日立製作所 | 生体分子分析装置及び生体分子分析方法 |
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| GB201902887D0 (en) * | 2019-03-04 | 2019-04-17 | St Georges Hospital Medical School | Detection and antibiotic resistance profiling of microorganisms |
| WO2020198664A1 (en) * | 2019-03-28 | 2020-10-01 | The Regents Of The University Of California | Methods and systems for sequencing cell-free microbiome dna |
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| IL255647B (en) | 2022-04-01 |
| US20260002197A1 (en) | 2026-01-01 |
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| EP4450636A3 (en) | 2025-01-01 |
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| JP7769480B2 (ja) | 2025-11-13 |
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| EP4450636A2 (en) | 2024-10-23 |
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| AU2016264102A1 (en) | 2017-12-21 |
| WO2016187234A1 (en) | 2016-11-24 |
| CA2986036C (en) | 2022-07-26 |
| JP6873921B2 (ja) | 2021-05-19 |
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