CN107861230A - 变焦光镊共聚焦显微成像装置及方法 - Google Patents
变焦光镊共聚焦显微成像装置及方法 Download PDFInfo
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- CN107861230A CN107861230A CN201711238079.1A CN201711238079A CN107861230A CN 107861230 A CN107861230 A CN 107861230A CN 201711238079 A CN201711238079 A CN 201711238079A CN 107861230 A CN107861230 A CN 107861230A
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- 238000012576 optical tweezer Methods 0.000 title claims abstract description 85
- 238000000034 method Methods 0.000 title claims abstract description 14
- 230000010287 polarization Effects 0.000 claims abstract description 25
- 238000007334 copolymerization reaction Methods 0.000 claims abstract description 17
- 238000003384 imaging method Methods 0.000 claims abstract description 11
- 230000003287 optical effect Effects 0.000 claims abstract description 7
- 239000013307 optical fiber Substances 0.000 claims description 14
- 238000006073 displacement reaction Methods 0.000 claims description 13
- 238000002591 computed tomography Methods 0.000 claims description 5
- 238000012360 testing method Methods 0.000 claims description 4
- 238000005388 cross polarization Methods 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000003325 tomography Methods 0.000 abstract description 3
- 238000000879 optical micrograph Methods 0.000 abstract description 2
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 238000011161 development Methods 0.000 description 2
- 238000013459 approach Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0028—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders specially adapted for specific applications, e.g. for endoscopes, ophthalmoscopes, attachments to conventional microscopes
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0036—Scanning details, e.g. scanning stages
- G02B21/0048—Scanning details, e.g. scanning stages scanning mirrors, e.g. rotating or galvanomirrors, MEMS mirrors
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- General Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Radiology & Medical Imaging (AREA)
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- Microscoopes, Condenser (AREA)
Abstract
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108956561A (zh) * | 2018-06-07 | 2018-12-07 | 浙江大学 | 基于扫描振镜的共聚焦与环形全内反射双模式显微镜系统 |
CN109211858A (zh) * | 2018-09-27 | 2019-01-15 | 北京海维尔科技发展有限公司 | 一种新型多通道激光扫描成像仪的光学模块 |
CN109884050A (zh) * | 2019-01-17 | 2019-06-14 | 哈尔滨工业大学 | 基于远距离调焦的消像差谐波显微测量方法 |
CN111722387A (zh) * | 2019-11-18 | 2020-09-29 | 中国科学院上海微系统与信息技术研究所 | 一种光学反射镜及激光扫描共聚焦显微镜 |
WO2021143525A1 (zh) * | 2020-01-18 | 2021-07-22 | 哈尔滨工业大学 | 一种横向差动暗场共焦显微测量装置及其方法 |
CN113466111A (zh) * | 2021-07-29 | 2021-10-01 | 武汉科技大学 | 一种单细胞分析系统及方法和应用 |
CN116909117A (zh) * | 2023-09-11 | 2023-10-20 | 成都理工大学工程技术学院 | 一种可变距光镊立体成像装置及成像方法 |
Citations (6)
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JP2005337730A (ja) * | 2004-05-24 | 2005-12-08 | Nara Institute Of Science & Technology | 測定システム |
CN101216414A (zh) * | 2007-12-29 | 2008-07-09 | 中国科学院西安光学精密机械研究所 | 多功能光学微操纵装置 |
CN101373267A (zh) * | 2008-10-14 | 2009-02-25 | 高秀敏 | 光学微操纵系统及其操控方法 |
CN101799482A (zh) * | 2010-01-28 | 2010-08-11 | 哈尔滨工业大学 | 一种近场光镊与afm探针的纳操作装置 |
WO2017075519A1 (en) * | 2015-10-29 | 2017-05-04 | Bahman Anvari | Combined optical micromanipulation and interferometric topography |
CN107422468A (zh) * | 2017-07-17 | 2017-12-01 | 鲁东大学 | 一种在物镜视场内任意移动细胞的环形光镊及实现方法 |
-
2017
- 2017-11-30 CN CN201711238079.1A patent/CN107861230B/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005337730A (ja) * | 2004-05-24 | 2005-12-08 | Nara Institute Of Science & Technology | 測定システム |
CN101216414A (zh) * | 2007-12-29 | 2008-07-09 | 中国科学院西安光学精密机械研究所 | 多功能光学微操纵装置 |
CN101373267A (zh) * | 2008-10-14 | 2009-02-25 | 高秀敏 | 光学微操纵系统及其操控方法 |
CN101799482A (zh) * | 2010-01-28 | 2010-08-11 | 哈尔滨工业大学 | 一种近场光镊与afm探针的纳操作装置 |
WO2017075519A1 (en) * | 2015-10-29 | 2017-05-04 | Bahman Anvari | Combined optical micromanipulation and interferometric topography |
CN107422468A (zh) * | 2017-07-17 | 2017-12-01 | 鲁东大学 | 一种在物镜视场内任意移动细胞的环形光镊及实现方法 |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108956561A (zh) * | 2018-06-07 | 2018-12-07 | 浙江大学 | 基于扫描振镜的共聚焦与环形全内反射双模式显微镜系统 |
CN109211858A (zh) * | 2018-09-27 | 2019-01-15 | 北京海维尔科技发展有限公司 | 一种新型多通道激光扫描成像仪的光学模块 |
CN109211858B (zh) * | 2018-09-27 | 2023-09-22 | 北京海维尔科技发展有限公司 | 一种多通道激光扫描成像仪的光学模块 |
CN109884050A (zh) * | 2019-01-17 | 2019-06-14 | 哈尔滨工业大学 | 基于远距离调焦的消像差谐波显微测量方法 |
CN109884050B (zh) * | 2019-01-17 | 2021-08-31 | 哈尔滨工业大学 | 基于远距离调焦的消像差谐波显微测量方法 |
CN111722387A (zh) * | 2019-11-18 | 2020-09-29 | 中国科学院上海微系统与信息技术研究所 | 一种光学反射镜及激光扫描共聚焦显微镜 |
WO2021143525A1 (zh) * | 2020-01-18 | 2021-07-22 | 哈尔滨工业大学 | 一种横向差动暗场共焦显微测量装置及其方法 |
CN113466111A (zh) * | 2021-07-29 | 2021-10-01 | 武汉科技大学 | 一种单细胞分析系统及方法和应用 |
CN113466111B (zh) * | 2021-07-29 | 2024-02-09 | 武汉科技大学 | 一种单细胞分析系统及方法和应用 |
CN116909117A (zh) * | 2023-09-11 | 2023-10-20 | 成都理工大学工程技术学院 | 一种可变距光镊立体成像装置及成像方法 |
CN116909117B (zh) * | 2023-09-11 | 2023-11-24 | 成都理工大学工程技术学院 | 一种可变距光镊立体成像装置及成像方法 |
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CN107861230B (zh) | 2020-04-28 |
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Effective date of registration: 20231220 Address after: Room 1107, 11 / F, National University Science Park, Harbin Institute of technology, No. 434, youyou street, Nangang District, Harbin City, Heilongjiang Province, 150001 Patentee after: Liu Jian Patentee after: Zhao Yixuan Patentee after: Harbin Institute of Technology Asset Management Co.,Ltd. Address before: 150001 No. 92 West straight street, Nangang District, Heilongjiang, Harbin Patentee before: HARBIN INSTITUTE OF TECHNOLOGY |
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Effective date of registration: 20240202 Address after: Room 304-2, Building 16, No. 1616, Chuangxin Road, Songbei District, Harbin, Heilongjiang Province, 150001 Patentee after: Rongyi Shangke photoelectric technology (Harbin) Co.,Ltd. Country or region after: China Address before: Room 1107, 11 / F, National University Science Park, Harbin Institute of technology, No. 434, youyou street, Nangang District, Harbin City, Heilongjiang Province, 150001 Patentee before: Liu Jian Country or region before: China Patentee before: Zhao Yixuan Patentee before: Harbin Institute of Technology Asset Management Co.,Ltd. |