CN107854658A - A kind of Chinese medicine composition for treating chronic pelvic inflammatory disease and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating chronic pelvic inflammatory disease and preparation method thereof Download PDFInfo
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- Biotechnology (AREA)
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Abstract
The invention discloses a kind of Chinese medicine composition for treating chronic pelvic inflammatory disease and preparation method thereof, it is characterised in that the Chinese medicine composition is made up of the raw material of following parts by weight：10 15 parts of radix bupleuri, 15 20 parts of the red sage root, 10 20 parts of Rhizoma Sparganii, 10 15 parts of curcuma zedoary, 15 25 parts of rhizoma cyperi, 15 30 parts of dandelion, 20 30 parts of honeysuckle, 10 15 parts of Radix Angelicae Sinensis, 10 20 parts of the radix paeoniae rubrathe, 8 15 parts of Fructus meliae toosendan, 10 20 parts of corydalis tuber, the present invention is according to drug matching mechanism, using with the radix bupleuri in inducing diaphoresis as monarch drug in a prescription, using the red sage root of promoting blood circulation, blood-breaking Mitsubishi as ministerial drug, the interaction of various medicinal materials, respective maximum effect has been given play to, has reached and thoroughly cures pelvic infecton and purpose uneasy to recur.
Description
Technical field
Patent of the present invention is related to a kind of Chinese medicine, especially a kind of Chinese medicine composition for treating chronic pelvic inflammatory disease and its preparation side
Method, belong to technical field of traditional Chinese medicines.
Background technology
Chronic pelvic inflammatory disease refers to the chronic inflammation of internal genital organs of female and surrounding connective tissue and pelvic peritoneum inflammation,
It is the common disease of gynaecology, and difficult treatment.Inflammation can be confined to a position, can also involve several positions.It includes intrauterine
Film inflammation, salpingitis, oaritis, pelvic peritonitis and connective tissue inflammation of pelvic cavity etc..Main clinical manifestation is paramenia, leukorrhea
Increase, waist abdomen pain and infertile etc., such as formed chronic appendages inflammation, then accessible lump.Doctor trained in Western medicine is controlled frequently with antimicrobial DP finish
Treat, seriously need to carry out operative treatment, but pelvic infecton be a kind of course of disease it is long, it is refractory more, the gynecological disease that easily recurs, doctor trained in Western medicine
It is extremely difficult thoroughly to cure.
The content of the invention
For the problems of the prior art, the invention aims to provide a kind of Chinese traditional medicine composition for treating chronic pelvic inflammatory disease
Thing and preparation method thereof, the Chinese medicine composition prepared by this method is safe and reliable, has no toxic side effect, quick, cheap.
In order to achieve the above object, the technical scheme is that：
A kind of Chinese medicine composition for treating chronic pelvic inflammatory disease, it is characterised in that the Chinese medicine composition by following parts by weight original
Material composition：Radix bupleuri 10-15 parts, red sage root 15-20 parts, Rhizoma Sparganii 10-20 parts, curcuma zedoary 10-15 parts, rhizoma cyperi 15-25 parts, dandelion 15-
30 parts, honeysuckle 20-30 parts, Radix Angelicae Sinensis 10-15 parts, radix paeoniae rubrathe 10-20 parts, Fructus meliae toosendan 8-15 parts, corydalis tuber 10-20 parts.
Preferably, the Chinese medicine composition is made up of the raw material of following parts by weight：12 parts of radix bupleuri, 18 parts of the red sage root, Rhizoma Sparganii
15 parts, 12 parts of curcuma zedoary, 20 parts of rhizoma cyperi, 25 parts of dandelion, 25 parts of honeysuckle, 12 parts of Radix Angelicae Sinensis, 15 parts of the radix paeoniae rubrathe, 12 parts of Fructus meliae toosendan, member
15 parts recklessly.
Preferably, the Chinese medicine composition is made up of the raw material of following parts by weight：15 parts of radix bupleuri, 18 parts of the red sage root, Rhizoma Sparganii
16 parts, 14 parts of curcuma zedoary, 22 parts of rhizoma cyperi, 28 parts of dandelion, 28 parts of honeysuckle, 13 parts of Radix Angelicae Sinensis, 15 parts of the radix paeoniae rubrathe, 10 parts of Fructus meliae toosendan, member
12 parts recklessly.
Invention also provides a kind of preparation method of the Chinese medicine composition for the treatment of chronic pelvic inflammatory disease as described above, its
It is characterised by that the preparation method comprises the following steps：
1) radix bupleuri, the red sage root, Rhizoma Sparganii, curcuma zedoary, rhizoma cyperi, dandelion, honeysuckle, Radix Angelicae Sinensis, the radix paeoniae rubrathe, melia toosendan, are weighed by weight
Son, corydalis tuber, screening removal of impurities, larger raw material are cut into the fritter of soya bean size, sterilized after well mixed under ultraviolet germicidal lamp
Processing 1 hour, it is subsequently placed in container and soaks 60-100 minutes with normal-temperature water；
2), the Chinese medicine material after immersion and the water of immersion are placed in marmite, after boiling by intense fire, slow fire heats 30 points
Clock, dry in the air after being down to 50-70 DEG C to temperature, take filtrate, the dregs of a decoction in marmite are standby, and filtrate is poured into container；
3), hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then be cooked by slow fire
20 minutes, dry in the air after being down to 50-70 DEG C to temperature, filter to obtain secondary decoction；
4), the decoction obtained in step 2) and step 3) is merged, and is well mixed, bottles or packs after drying in the air to room temperature,
Obtain Traditional Chinese medicine composition liquid medicine.
The above method prepare be for traditional Chinese herbal decoction, the instructions of taking of this traditional Chinese herbal decoction：Take in three times within 1 day.Also can be 1 time
Property decoct the dose of 2 days, filling and sealing after obtained decoction is sterilized, refrigeration, first micro- heating when taking.This Chinese traditional medicine composition
Thing can also be prepared into powder capsule, and concrete scheme is as follows：
The preparation method of the Chinese medicine composition for the treatment of chronic pelvic inflammatory disease as described above, it is characterised in that the preparation method bag
Include following steps：
1) radix bupleuri, the red sage root, Rhizoma Sparganii, curcuma zedoary, rhizoma cyperi, dandelion, honeysuckle, Radix Angelicae Sinensis, the radix paeoniae rubrathe, melia toosendan, are weighed by weight
Son, corydalis tuber, screening removal of impurities, larger raw material are cut into the fritter of soya bean size, sterilized after well mixed under ultraviolet germicidal lamp
Processing 1 hour, powder is then ground to, after crossing 500-800 mesh sieves point, obtains herb powder；
2), the herb powder for obtaining step 1), which is fitted into capsule skin, is made Chinese medicinal capsule.
Further, the preparation method 1) granularity of herb powder that obtains in step is 600 mesh
The Chinese medicine composition of the present invention has no toxic side effect, and therapeutic effect is good, treats both principal and secondary aspect of disease, uneasy to recur.
The pharmacology of all kinds of Chinese medicines is as follows in the present invention：
Radix bupleuri：Acrid flavour, hardship, cold nature.Return liver, courage, lung channel.In inducing diaphoresis, soothing liver-qi stagnation, yang invigorating, preventing malaria of bringing down a fever.
For cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, the prolapse of uterus, prolapse of the anus.
The red sage root：Bitter, it is slightly cold.The thoughts of returning home, Liver Channel.Effect：Promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle.It is main
Control：Swollen for chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhoea Amenorrhea, sore
Bitterly.
Rhizoma Sparganii：Nature and flavor：It is pungent, bitter, put down.Return liver, the spleen channel.Blood-breaking, Xiao Ji Zhi Tong.For abdominal mass lump in the abdomen, dysmenorrhoea, hemostasis
Amenorrhea, chest impediment and cardialgia, dyspepsia distending pain.
Curcuma zedoary：Nature and flavor：It is pungent, bitter, temperature.Return liver, the spleen channel.(1) blood-breaking, Xiao Ji Zhi Tong.Swollen for abdominal pain due to blood stasis, liver and spleen
Greatly, trusted subordinate's distending pain, accumulation, women's blood stasis, traumatic injury are had a pain eating accumulation.(2) promoting qi circulation and relieving pain, blood-breaking disperse accumulations：For
Amenorrhea, chest and hypochondrium, stomachache and abdominal mass lump of qi depression to blood stasis etc..Often match somebody with somebody Rhizoma Sparganii.(3) promoting digestion and removing indigestion：Stomach for eating accumulation
Abdominal distention and pain, often with melanoidin malt, charred SEMEN ARECAE.
Rhizoma cyperi：Nature and flavor：Pungent, slight bitter, micro-sweet, put down.Return liver, spleen, tri-jiao channel.Soothing liver-qi stagnation, regulating the flow of QI to ease the stomach, menstruction regulating and pain relieving.
For stagnation of QI due to depression of the liver, distending pain in the chest and hypochondrium, hernia pain, swollen breasts, the taste stagnation of the circulation of vital energy, gastral cavity abdomen ruffian is vexed, turgor pain, irregular menstruation,
Closed dysmenorrhea.
Dandelion：Dandelion, nature and flavor：Bitter sweet, tremble with fear.Enter liver, stomach.Major function：It is clearing heat and detoxicating, diuresis dissipating bind.Control urgency
Property mastitis, adenolymphitis, scrofula, boil poisonous soreness, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchus
Inflammation, gastritis, hepatitis, cholecystitis, urinary tract infections.
Two flowers：The nickname of honeysuckle.Honeysuckle is cold in nature, sweet, enters lung, the heart, stomach, has clearing heat and detoxicating, anti-inflammatory, qi-restoratives
The effect for the treatment of wind, cures mainly disease under turgor, warm disease heating, the disease such as heat toxin large carbuncle and tumour.Its for dizziness, thirst,
Sweating and boring, enteritis, bacillary dysentery, measles, pneumonia, encephalitis, epidemic meningitis, acute mastitis, septicemia, appendicitis, skin infection, ulcer
The illnesss such as furunculosis, erysipelas, parotitis, suppurative tonsillitis have certain curative effect.Modern study proves that honeysuckle contains green original
The pharmacological components such as acid, cyanidenon glycosides, to the various pathogens such as hemolytic streptococcus, Staphylococcus aureus and the upper respiratory tract
Infective virus etc. has stronger restraint, in addition can also strengthen immunity, Robust speaker feature, protect liver, antitumor, anti-inflammatory, it is antipyretic,
Stop blooding (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application is very extensive, can be exhaled with other medicines compatibility for treatment
Inhale road infection, bacillary dysentery, acute urinary, hypertension etc. more than 40 and plant illness.
Radix Angelicae Sinensis：Nature and flavor：It is sweet, pungent, warm.Return liver, the heart, the spleen channel.Major function：Enrich blood；Promoting blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.
The main all cards of the deficiency of blood；Irregular menstruation；Amenorrhea；Dysmenorrhoea；Abdominal mass knot gathers；Uterine bleeding；Asthenia cold abdominalgia；Impotence numbness；Numbness；Intestines are dry and shit is difficult；
Weight after dysentery characterized by blood in the stool；Ulcer sores；Injury from falling down.
The radix paeoniae rubrathe：Bitter, cold nature.Return liver warp.Clearing heat and cooling blood, blood stasis removing analgesic.For thermal man's ying blood, febrile virulent maculae, spit blood
Bleeding from five sense organs or subcutaneous tissue, red eye, swell pain, liver-depressed hypochondrium pain, closed dysmenorrhea, addiction lump in the abdomen stomachache, injury from falling down, carbuncle swells sore.
Fructus meliae toosendan：Nature and flavor：Hardship, tremble with fear.Return liver, small intestine, bladder warp.Effect：It is soothing the liver to expel the heat-evil, promoting qi circulation and relieving pain, desinsection.Cure mainly：
For liver depression forming fire, chest side of body, abdominal distention, hernia pain, abdominal pain due to enterositosis.
Corydalis tuber：Corydalis tuber acrid flavour, hardship, it is warm-natured.There are promoting blood circulation to remove blood stasis, the function of regulating qi-flowing for relieving pain.For each portion's qi depression to blood stasis of whole body
Pain, dysmenorrhoea, Amenorrhea, abdominal mass, postpartum stasis, injury from falling down, hernia are had a pain.
" organic conception " is had been accepted as at present, " diagnosis and treatment based on an overall analysis of the illness and the patient's condition ", " compound use ", " compound compatibility medication is such as used military forces " are the traditional Chinese medical science
Most scientific maximally effective several big advantages, wherein " compound compatibility medication is such as used military forces " is the original theory of traditional Chinese medicine of very science.In
The tight compatibility that each medicine is all linked with one another as arraying troops for battle in prescription is cured, is that it is better than the effective means of western medicine formula.The traditional Chinese medical science
Prescription theory thinks, each prescription, not only needs to select the suitable appropriate compatibility of medicine according to etiology and pathogenesis, while should also accord with
Close the prescription compatibility theory of the basic structure of prescription, i.e. " monarch, minister, help, make ", the prescription compatibility of so-called " monarch, minister, help, make ", just
It is that it establishes the scientific matching on the comprehensive judgement basis to the disease interpretation of the cause, onset and process of an illness.Middle medical square is whole by too many levels, Mutiple Targets
The biological mechanism of regulation is closed, therapeutic effect more more longlasting than Western medicine, that more green natural has no toxic side effect can be obtained, and it is this
Curative effect is built upon on the original theoretical accurate instruction of above-mentioned traditional Chinese medical science tradition, and the present invention just have followed this principle.
The Chinese medicine of the treatment chronic pelvic inflammatory disease can be prepared into the diversified forms such as Chinese medicinal tablet, particle, traditional Chinese medicine pill, not office
It is limited to decoction and capsule.
The present invention according to drug matching mechanism, using with the radix bupleuri in inducing diaphoresis as monarch drug in a prescription, with the red sage root of promoting blood circulation, blood-breaking row
The Mitsubishi of gas is ministerial drug, and wind is treated with the curcuma zedoary of Xiao Ji Zhi Tong, the rhizoma cyperi of soothing liver-qi stagnation, clearing heat and detoxicating dandelion, anti-inflammatory qi-restoratives
Honeysuckle, the Radix Angelicae Sinensis of replenishing and activating blood, the radix paeoniae rubrathe of clearing heat and cooling blood, the Fructus meliae toosendan of promoting qi circulation and relieving pain be adjutant, with promoting blood circulation to remove blood stasis, qi-regulating
Analgesic member is acted like a bully and makes medicine, various medicinal material interactions, has been given play to respective maximum effect, has been reached and thoroughly cure pelvic infecton and be not easy
The purpose of recurrence.The instructions of taking of this traditional Chinese herbal decoction is：Take in three times within 1 day.Also can 1 property decoct the dose of 2 days, will be made
Decoction sterilization after filling and sealing, refrigeration, first micro- heating when taking.
Embodiment
The present invention is further described with reference to embodiment.
Embodiment one：
A kind of Chinese medicine composition for treating chronic pelvic inflammatory disease, it is characterised in that the Chinese medicine by following parts by weight raw material group
Into：10 parts of radix bupleuri, 15 parts of the red sage root, 10 parts of Rhizoma Sparganii, 10 parts of curcuma zedoary, 15 parts of rhizoma cyperi, 15 parts of dandelion, 20 parts of honeysuckle, Radix Angelicae Sinensis 10
Part, 10 parts of the radix paeoniae rubrathe, 8 parts of Fructus meliae toosendan, 10 parts of corydalis tuber.
The present embodiment also discloses a kind of preparation method of the Chinese medicine composition for the treatment of chronic pelvic inflammatory disease as described above,
It is characterized in that the preparation method comprises the following steps：
1) 10 parts of radix bupleuri, 15 parts of the red sage root, 10 parts of Rhizoma Sparganii, 10 parts of curcuma zedoary, 15 parts of rhizoma cyperi, dandelion 15, are weighed by weight
Part, 20 parts of honeysuckle, 10 parts of Radix Angelicae Sinensis, 10 parts of the radix paeoniae rubrathe, 8 parts of Fructus meliae toosendan, 10 parts of corydalis tuber, screening removal of impurities, larger raw material are cut into Huang
The fritter of beans size, be well mixed after under ultraviolet germicidal lamp sterilization treatment 1 hour, be subsequently placed in container and use normal temperature water logging
Bubble 60 minutes；
2), the Chinese medicine material after immersion and the water of immersion are placed in marmite, after boiling by intense fire, slow fire heats 30 points
Clock, dry in the air after being down to 50 DEG C to temperature, take filtrate, the dregs of a decoction in marmite are standby, and filtrate is poured into container；
3), hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then be cooked by slow fire
20 minutes, dry in the air after being down to 50 DEG C to temperature, filter to obtain secondary decoction；
4), the decoction obtained in step 2) and step 3) is merged, and is well mixed, bottles or packs after drying in the air to room temperature,
Obtain Traditional Chinese medicine composition liquid medicine.
Embodiment two
A kind of Chinese medicine composition for treating chronic pelvic inflammatory disease, it is characterised in that the Chinese medicine composition by following parts by weight original
Material composition：15 parts of radix bupleuri, 20 parts of the red sage root, 20 parts of Rhizoma Sparganii, 15 parts of curcuma zedoary, 25 parts of rhizoma cyperi, 30 parts of dandelion, 30 parts of honeysuckle, when
Return 15 parts, 20 parts of the radix paeoniae rubrathe, 15 parts of Fructus meliae toosendan, 20 parts of corydalis tuber.
The present embodiment provides a kind of preparation method of the Chinese medicine composition for the treatment of chronic pelvic inflammatory disease as described above simultaneously,
It is characterized in that the preparation method comprises the following steps：
1) 15 parts of radix bupleuri, 20 parts of the red sage root, 20 parts of Rhizoma Sparganii, 15 parts of curcuma zedoary, 25 parts of rhizoma cyperi, dandelion 30, are weighed by weight
Part, 30 parts of honeysuckle, 15 parts of Radix Angelicae Sinensis, 20 parts of the radix paeoniae rubrathe, 15 parts of Fructus meliae toosendan, 20 parts of corydalis tuber, screening removal of impurities, larger raw material are cut into Huang
The fritter of beans size, after being well mixed under ultraviolet germicidal lamp sterilization treatment 1 hour, be then ground to powder, cross 500 mesh sieves point
Afterwards, herb powder is obtained；
2), the herb powder for obtaining step 1), which is fitted into capsule skin, is made Chinese medicinal capsule.
Embodiment three：
A kind of Chinese medicine composition for treating chronic pelvic inflammatory disease, it is characterised in that the Chinese medicine composition by following parts by weight original
Material composition：12 parts of radix bupleuri, 18 parts of the red sage root, 15 parts of Rhizoma Sparganii, 12 parts of curcuma zedoary, 20 parts of rhizoma cyperi, 25 parts of dandelion, 25 parts of honeysuckle, when
Return 12 parts, 15 parts of the radix paeoniae rubrathe, 12 parts of Fructus meliae toosendan, 15 parts of corydalis tuber.
The present embodiment provides a kind of preparation method of the Chinese medicine composition for the treatment of chronic pelvic inflammatory disease as described above simultaneously,
It is characterized in that the preparation method comprises the following steps：
1) 12 parts of radix bupleuri, 18 parts of the red sage root, 15 parts of Rhizoma Sparganii, 12 parts of curcuma zedoary, 20 parts of rhizoma cyperi, dandelion 25, are weighed by weight
Part, 25 parts of honeysuckle, 12 parts of Radix Angelicae Sinensis, 15 parts of the radix paeoniae rubrathe, 12 parts of Fructus meliae toosendan, 15 parts of corydalis tuber, screening removal of impurities, larger raw material are cut into Huang
The fritter of beans size, be well mixed after under ultraviolet germicidal lamp sterilization treatment 1 hour, be subsequently placed in container and use normal temperature water logging
Bubble 80 minutes；
2), the Chinese medicine material after immersion and the water of immersion are placed in marmite, after boiling by intense fire, slow fire heats 30 points
Clock, dry in the air after being down to 60 DEG C to temperature, take filtrate, the dregs of a decoction in marmite are standby, and filtrate is poured into container；
3), hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then be cooked by slow fire
20 minutes, dry in the air after being down to 60 DEG C to temperature, filter to obtain secondary decoction；
4), the decoction obtained in step 2) and step 3) is merged, and is well mixed, bottles or packs after drying in the air to room temperature,
Obtain Traditional Chinese medicine composition liquid medicine.
Example IV：
A kind of Chinese medicine composition for treating chronic pelvic inflammatory disease, it is characterised in that the Chinese medicine composition by following parts by weight original
Material composition：15 parts of radix bupleuri, 18 parts of the red sage root, 16 parts of Rhizoma Sparganii, 14 parts of curcuma zedoary, 22 parts of rhizoma cyperi, 28 parts of dandelion, 28 parts of honeysuckle, when
Return 13 parts, 15 parts of the radix paeoniae rubrathe, 10 parts of Fructus meliae toosendan, 12 parts of corydalis tuber.
The present embodiment provides a kind of preparation method of the Chinese medicine composition for the treatment of chronic pelvic inflammatory disease as described above simultaneously,
It is characterized in that the preparation method comprises the following steps：
1) 15 parts of radix bupleuri, 18 parts of the red sage root, 16 parts of Rhizoma Sparganii, 14 parts of curcuma zedoary, 22 parts of rhizoma cyperi, dandelion 28, are weighed by weight
Part, 28 parts of honeysuckle, 13 parts of Radix Angelicae Sinensis, 15 parts of the radix paeoniae rubrathe, 10 parts of Fructus meliae toosendan, 12 parts of corydalis tuber, screening removal of impurities, larger raw material are cut into Huang
The fritter of beans size, after being well mixed under ultraviolet germicidal lamp sterilization treatment 1 hour, be then ground to powder, cross 600 mesh sieves point
Afterwards, herb powder is obtained；
2), the herb powder for obtaining step 1), which is fitted into capsule skin, is made Chinese medicinal capsule.
Embodiment five：
A kind of Chinese medicine composition for treating chronic pelvic inflammatory disease, it is characterised in that the Chinese medicine composition by following parts by weight original
Material composition：15 parts of radix bupleuri, 18 parts of the red sage root, 16 parts of Rhizoma Sparganii, 14 parts of curcuma zedoary, 22 parts of rhizoma cyperi, 28 parts of dandelion, 28 parts of honeysuckle, when
Return 13 parts, 15 parts of the radix paeoniae rubrathe, 10 parts of Fructus meliae toosendan, 12 parts of corydalis tuber.
The present embodiment provides a kind of preparation method of the Chinese medicine composition for the treatment of chronic pelvic inflammatory disease as described above simultaneously,
It is characterized in that the preparation method comprises the following steps：
1) 15 parts of radix bupleuri, 18 parts of the red sage root, 16 parts of Rhizoma Sparganii, 14 parts of curcuma zedoary, 22 parts of rhizoma cyperi, dandelion 28, are weighed by weight
Part, 28 parts of honeysuckle, 13 parts of Radix Angelicae Sinensis, 15 parts of the radix paeoniae rubrathe, 10 parts of Fructus meliae toosendan, 12 parts of corydalis tuber, screening removal of impurities, larger raw material are cut into Huang
The fritter of beans size, be well mixed after under ultraviolet germicidal lamp sterilization treatment 1 hour, be subsequently placed in container and use normal temperature water logging
Bubble 80 minutes；
2), the Chinese medicine material after immersion and the water of immersion are placed in marmite, after boiling by intense fire, slow fire heats 30 points
Clock, dry in the air after being down to 70 DEG C to temperature, take filtrate, the dregs of a decoction in marmite are standby, and filtrate is poured into container；
3), hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then be cooked by slow fire
20 minutes, dry in the air after being down to 70 DEG C to temperature, filter to obtain secondary decoction；
4), the decoction obtained in step 2) and step 3) is merged, and is well mixed, bottles or packs after drying in the air to room temperature,
Obtain Traditional Chinese medicine composition liquid medicine.
The present invention has carried out clinical efficacy tracking with the data given by embodiment 1 simultaneously, and curative effect is summarized as follows：
1. choosing undergoing chronic pelvic inflammation 40, female, age 18-55 year, average age 38 years old, patient is randomly divided into two
There was no significant difference for the data such as group, treatment group 20, control group 20, two groups of ages, has comparativity.Its common typical disease
Shape is that lower abdomen falling inflation, pain and lumbosacral region are ached.Often aggravate after tired, standing, sexual intercourse for a long time and before and after menstruation.
2. treatment method, the oral Chinese medicine composition made from optimization formula embodiment 1 of the present invention for the treatment of group, per bu sooner or later
Take twice, the course for the treatment of 15 days.The oral benzydamine of control group is 3 times a day.Each taking 25mg, the course for the treatment of 15 days.
3. diagnostic criteria
All cases meet what State Administration of Traditional Chinese Medicine issued《Chinese medical disease diagnostic criteria》In " band under " diagnosis
Standard.It is all to meet the diagnosis of doctor trained in Western medicine chronic pelvic inflammatory disease or be included with pelvic lump person；
Cure:Patient symptom and sign all disappear；
It is effective:Patient's major part sings and symptoms disappears, and the display of gynecologial examination result improves obvious, B ultrasound prompting inflammatory bag
Block is obviously reduced；
Effectively:Patient symptom, sign have improvement, and B ultrasound prompting inflammatory mass reduces, and Mass volum reduces the scope small on time
In 2/3rds；
It is invalid:For patient symptom without improvement, inspection result shows that the state of an illness is unchanged or gets along with.
4. treatment results, the cure rate for the treatment of group is 60%, effective 15%, effective 15%, invalid 10%, total effective rate
90%；The cure rate of control group is 20%, effective 8%, effective 22%, invalid 50%, total effective rate 50%.Treatment group owns
Follow-up of patients one month, does not have found recurrence sign.
The Chinese medicine of the present invention has carried out toxicity test, and test effect is as follows：
To choose that the suitable adult of body weight is female, male each 20 of small white mouse, be divided into control group and administration group, rearing conditions are consistent,
Control group not medicine feed, the daily medicine feed of administration group 1 time, records the health of each small white mouse, ingests, drinks water, body weight daily, tries
Test lasting six months, compared with control group, administration group small white mouse health, ingest, drink water, body weight increase it is normal, and not
See that small white mouse is sick or dead.Prompt the medicine security good, have no toxic side effect.
The treatment case of the Chinese medicine of the present invention is as follows：
Case one, Zhu, 29 years old, female was married.Forward fallopian tubal conducting operation in 2 years, afterwards, lower abdomen falling inflation, belly are held
Continuous property secret anguish, with menstrual flow is reduced, menostaxis, tired postemphasis, doctor trained in Western medicine is diagnosed as chronic pelvic inflammatory disease, is controlled using antibiotic
Treat, recur again within 1 month after improvement, then do not alleviate symptom without any effect with antibiotic, then to where inventor
Chinese herbalist clinic goes to a doctor, and patient mental is dispirited, face is yellow powerless, awards Chinese medicine provided by the invention, and symptom disappears substantially after 7 days, after
Continue to take 2 weeks again, visited after 1 year, no recurrence.
Case two, Hu, 33 years old, female was married.After once overworking, there is underbelly secret anguish, leukorrhea amount is more, color hair
Yellow and stink is serious, and lassitude, the soreness of waist is weak, and red tongue with thin fur is white, soft and rapid pulse, is diagnosed as chronic pelvic inflammatory disease, takes the present invention
The Chinese medicine of offer, symptom is disappeared more than half after 7 days, and after taking 3 weeks again, symptom is wholly absent, and is visited after 1 year, no recurrence.
Case three, Zhang, female, 35 years old, lower abdomen falling inflation pain, lumbosacral region were ached 2 years repeatedly for readme, leucorrhea increasing first quarter moon.
Gynecologial examination：Retroposition of uterus, limitation of activity, tenderness can be laid one's hand at ride side attachment and 3cm X3cm X4cm enclosed mass, there is tenderness.B ultrasound
Check：Uterus increases (uterine cavity>8.5cm), ride side attachment thickens.It is diagnosed as chronic pelvic inflammatory disease.Chinese medicine provided by the invention is taken,
Subjective symptoms disappears after 15 days, and gynecologial examination enclosed mass disappears, and the few color of leukorrhea amount is white, ultrasound diagnosis uterus, annex normal in size.With
Visit 1 month and check not repeatedly.
Case four, permitted certain, female, 32 years old, postpartum gynecological disease took place frequently, and accidental underbelly pain, leukorrhea is more, and hospital diagnosis is slow
Property pelvic infecton, take Western medicine and washing lotion take a favorable turn after two weeks, be discontinued 5 days recur, take Chinese medicine provided by the invention, disease after 3 days
Shape disappears, then without pain.
It is understood that above with respect to the specific descriptions of the present invention, it is merely to illustrate the present invention and is not limited to this
Technical scheme described by inventive embodiments, it will be understood by those within the art that, still the present invention can be carried out
Modification or equivalent substitution, to reach identical technique effect；As long as meet use needs, all protection scope of the present invention it
It is interior.
Claims (6)
- A kind of 1. Chinese medicine composition for treating chronic pelvic inflammatory disease, it is characterised in that the Chinese medicine composition by following parts by weight raw material Composition：Radix bupleuri 10-15 parts, red sage root 15-20 parts, Rhizoma Sparganii 10-20 parts, curcuma zedoary 10-15 parts, rhizoma cyperi 15-25 parts, dandelion 15-30 Part, honeysuckle 20-30 parts, Radix Angelicae Sinensis 10-15 parts, radix paeoniae rubrathe 10-20 parts, Fructus meliae toosendan 8-15 parts, corydalis tuber 10-20 parts.
- A kind of 2. Chinese medicine composition for treating chronic pelvic inflammatory disease according to claim 1, it is characterised in that the Chinese traditional medicine composition Thing is made up of the raw material of following parts by weight：12 parts of radix bupleuri, 18 parts of the red sage root, 15 parts of Rhizoma Sparganii, 12 parts of curcuma zedoary, 20 parts of rhizoma cyperi, dandelion 25 parts, 25 parts of honeysuckle, 12 parts of Radix Angelicae Sinensis, 15 parts of the radix paeoniae rubrathe, 12 parts of Fructus meliae toosendan, 15 parts of corydalis tuber.
- A kind of 3. Chinese medicine composition for treating chronic pelvic inflammatory disease according to claim 1, it is characterised in that the Chinese traditional medicine composition Thing is made up of the raw material of following parts by weight：15 parts of radix bupleuri, 18 parts of the red sage root, 16 parts of Rhizoma Sparganii, 14 parts of curcuma zedoary, 22 parts of rhizoma cyperi, dandelion 28 parts, 28 parts of honeysuckle, 13 parts of Radix Angelicae Sinensis, 15 parts of the radix paeoniae rubrathe, 10 parts of Fructus meliae toosendan, 12 parts of corydalis tuber.
- 4. a kind of preparation method of the Chinese medicine composition for the treatment of chronic pelvic inflammatory disease as any one of claim 1-3, its It is characterised by that the preparation method comprises the following steps：1) radix bupleuri, the red sage root, Rhizoma Sparganii, curcuma zedoary, rhizoma cyperi, dandelion, honeysuckle, Radix Angelicae Sinensis, the radix paeoniae rubrathe, Fructus meliae toosendan, member, are weighed by weight Recklessly, screening removal of impurities, larger raw material is cut into the fritter of soya bean size, after being well mixed under ultraviolet germicidal lamp sterilization treatment 1 Hour, it is subsequently placed in container and soaks 60-100 minutes with normal-temperature water；2), the Chinese medicine material after immersion and the water of immersion are placed in marmite, after boiling by intense fire, slow fire heats 30 minutes, dries in the air After being down to 50-70 DEG C to temperature, filtrate is taken, the dregs of a decoction in marmite are standby, and filtrate is poured into container；3), hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then be cooked by slow fire 20 points Clock, dry in the air after being down to 50-70 DEG C to temperature, filter to obtain secondary decoction；4), the decoction obtained in step 2) and step 3) is merged, and is well mixed, bottles or packs after drying in the air to room temperature, in obtaining Drug composition decoction.
- 5. a kind of preparation method of the Chinese medicine composition for the treatment of chronic pelvic inflammatory disease as any one of claim 1-3, its It is characterised by that the preparation method comprises the following steps：1) radix bupleuri, the red sage root, Rhizoma Sparganii, curcuma zedoary, rhizoma cyperi, dandelion, honeysuckle, Radix Angelicae Sinensis, the radix paeoniae rubrathe, Fructus meliae toosendan, member, are weighed by weight Recklessly, screening removal of impurities, larger raw material is cut into the fritter of soya bean size, after being well mixed under ultraviolet germicidal lamp sterilization treatment 1 Hour, powder is then ground to, after crossing 500-800 mesh sieves point, obtains herb powder；2), the herb powder for obtaining step 1), which is fitted into capsule skin, is made Chinese medicinal capsule.
- A kind of 6. preparation method of Chinese medicine composition for treating chronic pelvic inflammatory disease according to claim 5, it is characterised in that The preparation method 1) granularity of herb powder that obtains in step is 600 mesh.
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| CN109464633A (en) * | 2018-12-29 | 2019-03-15 | 广东罗浮山国药股份有限公司 | A kind of application of Chinese medicine composition in the drug of preparation treatment softening hard masses Jie , lumps in the chest and abdomen |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109464633A (en) * | 2018-12-29 | 2019-03-15 | 广东罗浮山国药股份有限公司 | A kind of application of Chinese medicine composition in the drug of preparation treatment softening hard masses Jie , lumps in the chest and abdomen |
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