CN107835806A - 取代的氰基吡啶的催化氢化及制备取代的吡啶基甲基苯甲酰胺的方法 - Google Patents

取代的氰基吡啶的催化氢化及制备取代的吡啶基甲基苯甲酰胺的方法 Download PDF

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Publication number
CN107835806A
CN107835806A CN201680037551.2A CN201680037551A CN107835806A CN 107835806 A CN107835806 A CN 107835806A CN 201680037551 A CN201680037551 A CN 201680037551A CN 107835806 A CN107835806 A CN 107835806A
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CN
China
Prior art keywords
formula
catalyst
acid
iii
halogen
Prior art date
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Pending
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CN201680037551.2A
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English (en)
Chinese (zh)
Inventor
W·A·莫拉迪
G·施莱格尔
A·施纳特里尔
F·沃尔兹
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Bayer CropScience AG
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Bayer CropScience AG
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Publication date
Application filed by Bayer CropScience AG filed Critical Bayer CropScience AG
Publication of CN107835806A publication Critical patent/CN107835806A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201680037551.2A 2015-04-30 2016-04-26 取代的氰基吡啶的催化氢化及制备取代的吡啶基甲基苯甲酰胺的方法 Pending CN107835806A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15165831.7 2015-04-30
EP15165831.7A EP3088390A1 (en) 2015-04-30 2015-04-30 Catalytic hydrogenation of substituted cyanopyridines
PCT/EP2016/059215 WO2016173998A1 (en) 2015-04-30 2016-04-26 Catalytic hydrogenation of substituted cyanopyridines and process for preparing substituted pyridylmethylbenzamides

Publications (1)

Publication Number Publication Date
CN107835806A true CN107835806A (zh) 2018-03-23

Family

ID=53040390

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201680037551.2A Pending CN107835806A (zh) 2015-04-30 2016-04-26 取代的氰基吡啶的催化氢化及制备取代的吡啶基甲基苯甲酰胺的方法

Country Status (12)

Country Link
US (1) US10781176B2 (enExample)
EP (2) EP3088390A1 (enExample)
JP (1) JP6910957B2 (enExample)
KR (1) KR102526835B1 (enExample)
CN (1) CN107835806A (enExample)
BR (1) BR112017023411B1 (enExample)
DK (1) DK3288922T3 (enExample)
ES (1) ES2906727T3 (enExample)
IL (1) IL255059B (enExample)
MX (1) MX388855B (enExample)
TW (1) TWI709555B (enExample)
WO (1) WO2016173998A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110606827A (zh) * 2019-09-26 2019-12-24 西安凯立新材料股份有限公司 一步法合成甲氨基吡啶类化合物的方法
CN111138351A (zh) * 2020-01-13 2020-05-12 大连九信精细化工有限公司 一种2-氨甲基-3-氯-5-三氟甲基吡啶醋酸盐的合成方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3489221A1 (en) 2017-11-22 2019-05-29 Bayer AG Process for the preparation of fluopicolide
CN107814759A (zh) * 2017-11-24 2018-03-20 常州沃腾化工科技有限公司 氟吡菌胺的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5105011A (en) * 1989-07-20 1992-04-14 Rhone-Poulenc Chimie Process for the hydrogenation of halogenonitro-aromatic compounds in the presence of an iodide
CN1291187A (zh) * 1998-02-19 2001-04-11 阿方蒂农科英国有限公司 用作杀真菌剂的2－吡啶基甲胺衍生物
CN1721406A (zh) * 2000-08-25 2006-01-18 拜尔农科股份有限公司 制备2－氰基吡啶的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9300433A (es) 1992-01-28 1994-07-29 Kirin Brewery Compuestos de piridincarboximidamina y composiciones farmaceuticas que los contienen.
JPH07138209A (ja) * 1993-11-12 1995-05-30 Sumitomo Seika Chem Co Ltd 含ハロゲンアミノメチル化合物の製造法
WO2002016322A2 (en) 2000-08-25 2002-02-28 Bayer Cropscience Sa Process for the preparation of 2-aminoethylpyridines
ES2545477T3 (es) * 2000-08-25 2015-09-11 Bayer S.A.S. Procedimiento de preparación de derivados de la 2-cianopiridina
GB0025616D0 (en) * 2000-10-19 2000-12-06 Aventis Cropscience Sa Novel process
EP1422221A1 (en) * 2002-11-20 2004-05-26 Bayer CropScience SA Novel process for the preparation of 2-aminomethylpyridine derivative
AU2007307031B2 (en) * 2006-10-11 2011-11-24 Amgen Inc. Imidazo- and triazolo-pyridine compounds and methods of use therof
JP5659860B2 (ja) * 2011-02-28 2015-01-28 エヌ・イーケムキャット株式会社 ニトリル化合物水素化用パラジウム含有触媒および該触媒を用いたニトリル化合物の水素化方法
WO2013048928A1 (en) * 2011-09-27 2013-04-04 Bristol-Myers Squibb Company Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5105011A (en) * 1989-07-20 1992-04-14 Rhone-Poulenc Chimie Process for the hydrogenation of halogenonitro-aromatic compounds in the presence of an iodide
CN1291187A (zh) * 1998-02-19 2001-04-11 阿方蒂农科英国有限公司 用作杀真菌剂的2－吡啶基甲胺衍生物
CN1721406A (zh) * 2000-08-25 2006-01-18 拜尔农科股份有限公司 制备2－氰基吡啶的方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110606827A (zh) * 2019-09-26 2019-12-24 西安凯立新材料股份有限公司 一步法合成甲氨基吡啶类化合物的方法
CN110606827B (zh) * 2019-09-26 2023-03-14 西安凯立新材料股份有限公司 一步法合成甲氨基吡啶类化合物的方法
CN111138351A (zh) * 2020-01-13 2020-05-12 大连九信精细化工有限公司 一种2-氨甲基-3-氯-5-三氟甲基吡啶醋酸盐的合成方法

Also Published As

Publication number Publication date
EP3088390A1 (en) 2016-11-02
KR102526835B1 (ko) 2023-04-27
EP3288922B1 (en) 2021-12-22
DK3288922T3 (da) 2022-03-14
US20180297952A1 (en) 2018-10-18
TWI709555B (zh) 2020-11-11
US10781176B2 (en) 2020-09-22
IL255059A0 (en) 2017-12-31
JP2018515468A (ja) 2018-06-14
BR112017023411A2 (pt) 2018-08-28
MX388855B (es) 2025-03-20
MX2017013919A (es) 2018-01-15
ES2906727T3 (es) 2022-04-20
JP6910957B2 (ja) 2021-07-28
WO2016173998A1 (en) 2016-11-03
TW201704213A (zh) 2017-02-01
IL255059B (en) 2020-03-31
EP3288922A1 (en) 2018-03-07
KR20170141771A (ko) 2017-12-26
BR112017023411B1 (pt) 2022-01-04

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