CN107811181A - A kind of person in middle and old age's sports drink containing marine oligosaccharide - Google Patents
A kind of person in middle and old age's sports drink containing marine oligosaccharide Download PDFInfo
- Publication number
- CN107811181A CN107811181A CN201711085454.3A CN201711085454A CN107811181A CN 107811181 A CN107811181 A CN 107811181A CN 201711085454 A CN201711085454 A CN 201711085454A CN 107811181 A CN107811181 A CN 107811181A
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- CN
- China
- Prior art keywords
- person
- sports drink
- old age
- oligosaccharide
- containing marine
- Prior art date
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- Pending
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- 235000011496 sports drink Nutrition 0.000 title claims abstract description 56
- 229920001542 oligosaccharide Polymers 0.000 title claims abstract description 36
- 150000002482 oligosaccharides Chemical class 0.000 title claims abstract description 36
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 45
- RQFQJYYMBWVMQG-IXDPLRRUSA-N chitotriose Chemical compound O[C@@H]1[C@@H](N)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](N)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)[C@@H](CO)O1 RQFQJYYMBWVMQG-IXDPLRRUSA-N 0.000 claims abstract description 31
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims abstract description 30
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims abstract description 30
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 30
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims abstract description 30
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 239000002994 raw material Substances 0.000 claims abstract description 17
- 239000012153 distilled water Substances 0.000 claims abstract description 16
- 229930091371 Fructose Natural products 0.000 claims abstract description 15
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims abstract description 15
- 239000005715 Fructose Substances 0.000 claims abstract description 15
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims abstract description 15
- 235000019341 magnesium sulphate Nutrition 0.000 claims abstract description 15
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims abstract description 15
- 235000020733 paullinia cupana extract Nutrition 0.000 claims abstract description 15
- 239000001103 potassium chloride Substances 0.000 claims abstract description 15
- 235000011164 potassium chloride Nutrition 0.000 claims abstract description 15
- 239000011780 sodium chloride Substances 0.000 claims abstract description 15
- 229960003080 taurine Drugs 0.000 claims abstract description 15
- WGIWBXUNRXCYRA-UHFFFAOYSA-H trizinc;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O WGIWBXUNRXCYRA-UHFFFAOYSA-H 0.000 claims abstract description 15
- 239000000811 xylitol Substances 0.000 claims abstract description 15
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims abstract description 15
- 229960002675 xylitol Drugs 0.000 claims abstract description 15
- 235000010447 xylitol Nutrition 0.000 claims abstract description 15
- 235000006076 zinc citrate Nutrition 0.000 claims abstract description 15
- 239000011746 zinc citrate Substances 0.000 claims abstract description 15
- 229940068475 zinc citrate Drugs 0.000 claims abstract description 15
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims abstract description 14
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000001630 malic acid Substances 0.000 claims abstract description 14
- 235000011090 malic acid Nutrition 0.000 claims abstract description 14
- 235000010323 ascorbic acid Nutrition 0.000 claims abstract description 10
- 229960005070 ascorbic acid Drugs 0.000 claims abstract description 10
- 239000011668 ascorbic acid Substances 0.000 claims abstract description 10
- GDSOZVZXVXTJMI-SNAWJCMRSA-N (e)-1-methylbut-1-ene-1,2,4-tricarboxylic acid Chemical compound OC(=O)C(/C)=C(C(O)=O)\CCC(O)=O GDSOZVZXVXTJMI-SNAWJCMRSA-N 0.000 claims description 5
- 230000006196 deacetylation Effects 0.000 claims description 4
- 238000003381 deacetylation reaction Methods 0.000 claims description 4
- 240000003444 Paullinia cupana Species 0.000 claims description 3
- 235000000556 Paullinia cupana Nutrition 0.000 claims description 3
- 230000002929 anti-fatigue Effects 0.000 abstract description 17
- 239000003792 electrolyte Substances 0.000 abstract description 2
- 206010021143 Hypoxia Diseases 0.000 abstract 1
- 230000007954 hypoxia Effects 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 150000003722 vitamin derivatives Chemical class 0.000 abstract 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 18
- 230000033001 locomotion Effects 0.000 description 17
- 238000002474 experimental method Methods 0.000 description 16
- 230000000694 effects Effects 0.000 description 13
- 229920002527 Glycogen Polymers 0.000 description 12
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- 241000219112 Cucumis Species 0.000 description 4
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- 241000699670 Mus sp. Species 0.000 description 4
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- 239000003963 antioxidant agent Substances 0.000 description 4
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- 238000006243 chemical reaction Methods 0.000 description 3
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 description 2
- 102100026189 Beta-galactosidase Human genes 0.000 description 2
- 206010007559 Cardiac failure congestive Diseases 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 206010061216 Infarction Diseases 0.000 description 2
- 108010059881 Lactase Proteins 0.000 description 2
- MBLBDJOUHNCFQT-LXGUWJNJSA-N N-acetylglucosamine Natural products CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO MBLBDJOUHNCFQT-LXGUWJNJSA-N 0.000 description 2
- 102000019197 Superoxide Dismutase Human genes 0.000 description 2
- 108010012715 Superoxide dismutase Proteins 0.000 description 2
- UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 description 2
- 108010005774 beta-Galactosidase Proteins 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
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- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 2
- 230000007574 infarction Effects 0.000 description 2
- 229940116108 lactase Drugs 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
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- 150000002926 oxygen Chemical class 0.000 description 2
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- 102100035882 Catalase Human genes 0.000 description 1
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- 229920002101 Chitin Polymers 0.000 description 1
- 229920001661 Chitosan Polymers 0.000 description 1
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- 101710145505 Fiber protein Proteins 0.000 description 1
- 241000581650 Ivesia Species 0.000 description 1
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- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 description 1
- OVRNDRQMDRJTHS-RTRLPJTCSA-N N-acetyl-D-glucosamine Chemical compound CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-RTRLPJTCSA-N 0.000 description 1
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical group CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 description 1
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- RJGDLRCDCYRQOQ-UHFFFAOYSA-N anthrone Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3CC2=C1 RJGDLRCDCYRQOQ-UHFFFAOYSA-N 0.000 description 1
- 230000000078 anti-malarial effect Effects 0.000 description 1
- 230000001857 anti-mycotic effect Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 239000003430 antimalarial agent Substances 0.000 description 1
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- 229930182478 glucoside Natural products 0.000 description 1
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- 229920000140 heteropolymer Polymers 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Non-Alcoholic Beverages (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to a kind of sports drink, more particularly to a kind of person in middle and old age's sports drink containing marine oligosaccharide.The person in middle and old age's sports drink for containing marine oligosaccharide per 1L includes the raw material of following weight：The 2.0g of chitosan oligosaccharide 0.1, the 2.0g of guarana extract 0.1, the 0.2g of taurine 0.01, the 2.0g of malic acid 0.05, the 10.0g of fructose 1.0, the 30.0g of xylitol 10.0, the 2.0mg of zinc citrate 0.1, the 0.3g of ascorbic acid 0.1, the 3.0g of citric acid 1.0, the 3g of potassium chloride 0.01, the 1.2g of magnesium sulfate 0.2, the 10.0g of sodium chloride 0.1, remaining is supplied with distilled water.The present invention uses the main component of chitosan oligosaccharide and guarana extract as person in middle and old age's sports drink, it is aided with other antifatigue raw materials simultaneously and adds appropriate electrolyte, sugar, vitamin and moisture, adaptability of the body to nonspecific stimulation can be strengthened, reduce Fatique after Sports sense, improve hypoxia-bearing capability and locomitivity, promote body to be rapidly achieved new balance, so as to dispelling fatigue, regain one's strength.
Description
Technical field
The present invention relates to a kind of sports drink, more particularly to a kind of person in middle and old age's sports drink containing marine oligosaccharide.
Background technology
Motion is the important means that the elderly improves health, prolonged life.However, for the elderly, amount of exercise is simultaneously
Non- to be the bigger the better, excessive movement can make body's immunity suffer damage, unhealthful.Because the elderly is in strenuous exercise,
The hormones such as more adrenaline and cortisol can be produced in vivo, when these hormones increase to certain amount, can make immune device
Spleen in official produces leukogenic ability and is greatly lowered, and causes the A cells in lymphocyte, the activity of B cell to substantially reduce.
Exercise induced fatigue is defined as that " physical function physiology course can not continue in a certain spy by the 5th international movement biochemistry meeting
Fixed horizontal and (or) each organ can not maintain a kind of state of its predetermined exercise intensity ".The reason for causing exercise induced fatigue is main
It is consuming excessively for energy substance, the accumulation of fatigue substances in vivo, the mistake of internal acid-base balance, osmotic balance, water balance
Adjust.
" exercise makes one strong ", person in middle and old age increasingly pay attention to improving the quality of body by sports, while also more next
The more recovery of physical function and the elimination of exercise induced fatigue after concern motion.Sports drink is the spy consumed according to physiology during motion
Point and prepare, holdings, raising locomitivity are played in the targetedly nutrition lost during supplement motion, tired after accelerated motion
The effect that labor eliminates.However, at present sports drink on the market mainly by keeping the skin wet, sugar and electrolyte, additionization
Learn medicine and biological products and reach and improve locomitivity, the effect of dispelling fatigue.But these sports drinks do not consider
Such as the different demands as special populations such as the elderly, fat or diabetics.Therefore, according to middle-aged and old maincenters god
Physilogical characteristics through, cardiovascular, breathing, kinematic system, dissect motion exercise to circulation, endocrine, breathing, nerve in person in middle and old age
The function effects such as system, find a kind of safe and effective fatigue resistant sport drink for being adapted to various mid-aged populations and have become
The study hotspot of sports medical science research field.
The content of the invention
To solve the shortcomings of the prior art, the present invention provides a kind of antifatigue motion drink for being suitable for mid-aged population
Material, fill up the blank of person in middle and old age's fatigue resistant sport drink in the market.
The technical scheme is that：
A kind of person in middle and old age's sports drink containing marine oligosaccharide, person in middle and old age's sports drink containing marine oligosaccharide described in per 1L
Include the raw material of following weight：Chitosan oligosaccharide 0.1-2.0g, guarana extract 0.1-2.0g, taurine 0.01-0.2g, apple
Sour 0.05-2.0g, fructose 1.0-10.0g, xylitol 10.0-30.0g, zinc citrate 0.1-2.0mg, ascorbic acid 0.1-
0.3g, citric acid 1.0-3.0g, potassium chloride 0.01-3g, magnesium sulfate 0.2-1.2g, sodium chloride 0.1-10.0g, remaining is with distilled water
Supply.
Preferably, person in middle and old age's sports drink containing marine oligosaccharide described in every 1L includes the raw material of following weight：Shell is few
Sugared 1.0g, guarana extract 2.0g, taurine 0.15g, malic acid 0.1g, fructose 5.0g, xylitol 20.0g, zinc citrate
1.0mg, ascorbic acid 0.2g, citric acid 2.0g, potassium chloride 1.5g, magnesium sulfate 0.6g, sodium chloride 5g, remaining is mended with distilled water
Foot.
Preferably, person in middle and old age's sports drink containing marine oligosaccharide described in every 1L includes the raw material of following weight：Shell is few
Sugared 0.5g, guarana extract 0.5g, taurine 0.15g, malic acid 0.1g, fructose 5.0g, xylitol 20.0g, zinc citrate
1.0mg, ascorbic acid 0.2g, citric acid 2.0g, potassium chloride 1.5g, magnesium sulfate 0.6g, sodium chloride 5g, remaining is mended with distilled water
Foot.
Preferably, person in middle and old age's sports drink containing marine oligosaccharide described in every 1L includes the raw material of following weight：Shell is few
Sugared 1.5g, guarana extract 1.0g, taurine 0.15g, malic acid 0.1g, fructose 5.0g, xylitol 20.0g, zinc citrate
1.0mg, ascorbic acid 0.2g, citric acid 2.0g, potassium chloride 1.5g, magnesium sulfate 0.6g, sodium chloride 5g, remaining is mended with distilled water
Foot.
Preferably, person in middle and old age's sports drink containing marine oligosaccharide described in every 1L includes the raw material of following weight：Shell is few
Sugared 2.0g, guarana extract 1.5g, taurine 0.15g, malic acid 0.1g, fructose 5.0g, xylitol 20.0g, zinc citrate
1.0mg, ascorbic acid 0.2g, citric acid 2.0g, potassium chloride 1.5g, magnesium sulfate 0.6g, sodium chloride 5g, remaining is mended with distilled water
Foot.
Further, deacetylation >=90% of the chitosan oligosaccharide.
Further, the average molecular weight of the chitosan oligosaccharide is 200~1000Da.
Further, purity >=90% of the chitosan oligosaccharide.
Further, guarana extractive content >=20%.
The beneficial effects of the invention are as follows：
Guarana extract in person in middle and old age's sports drink of the invention containing marine oligosaccharide can improve the elderly and exist
Physiology ability to bear in motion process, promote blood vessel dilatation, the oxygen supply energy of increase the elderly incidence in motion process
Power, heartbeat ability is improved, dizziness, miocardial infarctions occurs in motion process in preventing and treating the elderly, the disease such as have a weak heart.
Meanwhile the chitosan oligosaccharide in person in middle and old age's sports drink of the invention can improve the immunity of middle-aged and old bodies, after alleviating motion
Immunosupress reaction.In addition, chitosan oligosaccharide structure institute band amino has reproducibility, amount of activated oxygen can be directly removed.Chitosan oligosaccharide
Antioxidant system in reinforcement, the activity of the antioxidases such as superoxide dismutase, catalase is improved, it is old in can removing
Year people after exercise in vivo caused by excessive free radical and lactic acid, alleviate oxidative stress status caused by motion to the elderly
Damage caused by cell and bone.
Person in middle and old age's sports drink of the invention containing marine oligosaccharide can improve the locomitivity of the elderly, while and can
Rapid recovery the elderly's Fatique after Sports state and immunosupress reaction.In addition, the person in middle and old age of the invention containing marine oligosaccharide
Sports drink active ingredient has the characteristics that safety, nutrition, meets the demand of the elderly's motion.
Embodiment
The present invention is further elaborated with effect test with reference to specific embodiment.
The present invention theoretical foundation be：
Chitosan oligosaccharide：It is 2-Acetamido-2-deoxy-D-glucose (GlcNAc) and Glucosamine (GlcN) with β-Isosorbide-5-Nitrae glucosides key connection
The homopolymer or heteropolymer formed.Chitosan oligosaccharide itself amino is positively charged, is the unique alkaline oligosaccharides being currently known.Chitosan oligosaccharide one
As using chitin or chitosan as raw material, make and obtain after enzymatic conversion and chemical method deacetylation, it is nontoxic, there is preferable life
Thing compatibility and biodegradability.The bioactivity of chitosan oligosaccharide is dependent on molecular mass, the degree of polymerization, deacetylation.Chitosan oligosaccharide
Tumour growth can be suppressed, suppress inflammatory reaction, there is the effect such as antibacterium, anti-malarial, antimycotic, anti-oxidant and strengthen immunity.
In terms of inflammatory reaction is suppressed, chitosan oligosaccharide can suppress the generation of all kinds of inflammatory mediators, moreover it is possible to suppress areas of inflammation cell and be situated between in vain
Element, TNF produce, and reduce inflammation damage；Other chitosan oligosaccharide suppresses nuclear factor at the too drastic position of inflammation, blocks
Inflammation key initial step and secondary inflammatory reaction.At anti-oxidant aspect, chitosan oligosaccharide structure institute band amino has reproducibility, can be straight
Connect and remove amount of activated oxygen, while antioxidant system in chitosan oligosaccharide reinforcement, not only improve superoxide dismutase, hydrogen peroxide
The activity of the antioxidases such as enzyme, it can be synthesized with expression of the inducing metal containing sulfoprotein, protection sulfydryl, improve body total antioxidation
Ability.In terms of strengthen immunity, the chitosan oligosaccharide activation more fibroblasts of wound circumference, increase clostridiopetidase A in fibroblast
Release, promote cell mitogen, be advantageous to the healing of wound.
Guarana extract：Its Main Ingredients and Appearance is Guarana because that can strengthen the physiological function and at elevated pressures of human body
Physiology is withstood forces, and strengthens memory, while can also reduce high cholesterol, aliphatic acid, adjustment blood circulation.In addition, guarana
Extract the effect of activated fiber protein dissolution and can also be metabolized in vivo, can consume and synthesized the required CoA of Cholersterol,
And then obvious vasorelaxation action is shown, make the oxygen supply and application amount at each portion's tissue particularly head, neck and each position
Substantial increase, cerebral vessels and the various lesions caused by angiemphraxis disease are effectively improved, and heartbeat can be stimulated, strong heart has
Effect is prevented miocardial infarction and had a weak heart.
Embodiment 1
A kind of person in middle and old age's sports drink containing marine oligosaccharide includes the raw material of following weight per 1L：Chitosan oligosaccharide 1.0g, melon
Draw that extract 2.0g, taurine 0.15g, malic acid 0.1g, fructose 5.0g, xylitol 20.0g, zinc citrate 1.0mg, anti-bad
Hematic acid 0.2g, citric acid 2.0g, potassium chloride 1.5g, magnesium sulfate 0.6g, sodium chloride 5g, remaining is supplied with distilled water.
Embodiment 2
A kind of person in middle and old age's sports drink containing marine oligosaccharide includes the raw material of following weight per 1L：Chitosan oligosaccharide 0.5g, melon
Draw that extract 0.5g, taurine 0.15g, malic acid 0.1g, fructose 5.0g, xylitol 20.0g, zinc citrate 1.0mg, anti-bad
Hematic acid 0.2g, citric acid 2.0g, potassium chloride 1.5g, magnesium sulfate 0.6g, sodium chloride 5g, remaining is supplied with distilled water.
Embodiment 3
A kind of person in middle and old age's sports drink containing marine oligosaccharide includes the raw material of following weight per 1L：Chitosan oligosaccharide 1.5g, melon
Draw that extract 1.0g, taurine 0.15g, malic acid 0.1g, fructose 5.0g, xylitol 20.0g, zinc citrate 1.0mg, anti-bad
Hematic acid 0.2g, citric acid 2.0g, potassium chloride 1.5g, magnesium sulfate 0.6g, sodium chloride 5g, remaining is supplied with distilled water.
Embodiment 4
A kind of person in middle and old age's sports drink containing marine oligosaccharide includes the raw material of following weight per 1L：Chitosan oligosaccharide 2.0g, melon
Draw that extract 1.5.0g, taurine 0.15g, malic acid 0.1g, fructose 5.0g, xylitol 20.0g, zinc citrate 1.0mg, anti-
Bad hematic acid 0.2g, citric acid 2.0g, potassium chloride 1.5g, magnesium sulfate 0.6g, sodium chloride 5g, remaining is supplied with distilled water.
Embodiment 5
The antifatigue animal experiment of person in middle and old age's sports drink containing marine oligosaccharide.
1st, experiment purpose：Whether person in middle and old age sports drink of the observation containing marine oligosaccharide has antifatigue effect.
2nd, experiment material and method：
2.1st, sample：Using the person in middle and old age's sports drink containing marine oligosaccharide being formulated described in embodiment 1 (in hereinafter referred to as
Old sports drink).
2.2nd, experimental animal：Kunming mice (male), 120, body weight 18-22g.
2.3rd, experiment packet and dosage choice：
4 groups of experiment point, every group of 3 repetitions, according to drinks human intaking amount (120mL/d, equivalent to 2.5mg/
Kgbw), respectively by its 5 times, 10 times, 20 times of designs, 3 dosage groups be 12.5,25,50mL/ (kgbw), and distilled water
Control group.By the body weight gavage of mouse.
2.4th, experimental method：
Animal adaptability is fed 2~3 days, weighs after empty stomach 12h, is grouped at random with reference to body weight.Experiment carries out 4 altogether
Week.Body weight is surveyed weekly once during experiment, and according to weight status gavage.
2.5th, detection project and method are tested：
2.5.1, bear a heavy burden 5% swimming test：During experiment, to 30min after experiment mice gavage, bound quite in mouse tail
In the load of body weight 5%, it is put into 25 DEG C of water, forces its swimming with a load attached to the body, record its swimming time.
2.5.2, Serum lactic acid content：During experiment, after experiment mice gavage 30min, it is allowed to carry out 10min swimming exercise
(water temperature be 25 DEG C or so), its tail blood is adopted after 30min and centrifuges to obtain serum, its Serum lactic acid content is surveyed with parazon method.
2.5.3, liver glycogen content：During experiment, to 30min after experiment mice gavage, killed and take its liver at once, passed through
Freezing after 0.85% physiological saline processing.Its hepatic glycogen content is detected with anthrone method.
3rd, experimental result：
3.1st, bear a heavy burden 5% antifatigue swimming test：The raising of exercise tolerance is that anti-fatigue ability strengthens most directly performance,
The length of swimming time can reflect the degree of animal movement fatigue.Its statistics see the table below：
Table 1：The antifatigue 5% swimming test data statistics result table (minute meter) that bears a heavy burden of person in middle and old age's sports drink
| Control group | 5 times of groups | 10 times of groups | 20 times of groups | |
| Number of animals (only) | 30 | 30 | 30 | 30 |
| Swimming time | 9.37±5.56 | 16.76±13.42 | 16.09±6.96 | 25.66±14.33 |
| P values | 0.13 | 0.025* | 0.0036** |
Note：* represent to compare with significant difference with control group.
* represents to compare with significant differences with control group.
The antifatigue swimming test statistics display of mouse heavy burden 5%, by giving mouse person in middle and old age's sports drink gavage 4 weeks,
Gavage group 5% swimming time of heavy burden is substantially longer than control group, and 10 times of groups of person in middle and old age's sports drink and person in middle and old age's sports drink
20 times of group significant differences, there is statistical significance, tentatively illustrate that the product has remarkable result to extending mouse swimming time.
3.2nd, Serum lactic acid content：The number of Serum lactic acid content caused by energetic supersession can react to a certain extent after motion
Its anti-fatigue ability, caused blood lactase acid is fewer, and its antifatigue effect is stronger.Experimental result data statistical result is as follows：
Table 2：The antifatigue experiment blood lactase acid experimental data statistical form (mg/l) of person in middle and old age's sports drink
| Control group | 5 times of groups | 10 times of groups | 20 times of groups | |
| Number of animals (only) | 30 | 30 | 30 | 30 |
| Serum lactic acid content | 1783.2±466.4 | 1304.4±406.0 | 934.2±193.4 | 1345.2±310.2 |
| P values | 0.024* | 4.7*10-5** | 0.029* |
Note：* represent to compare with significant difference with control group.
* represents to compare with significant differences with control group.
The antifatigue mouse Serum lactic acid content of person in middle and old age's sports drink is shown：The blood breast of three dosage groups of person in middle and old age's sports drink
Acid content is substantially less than control group, and is examined through t, is respectively provided with statistical significance, illustrates person in middle and old age's sports drink to enhancing
The anti-fatigue ability of mouse has remarkable result.
3.3rd, hepatic glycogen content：
Hepatic glycogen is energy source main in energetic supersession, and it is antifatigue that the number of animal itself hepatic glycogen can react itself
Ability, hepatic glycogen is more, its be resistant to fatigue ability it is stronger.It is as follows to be tested data statistics result：
Table 3：The antifatigue experiment liver glycogen data statistic (mg/100g mouse liver) of person in middle and old age's sports drink
| Control group | 5 times of groups | 10 times of groups | 20 times of groups | |
| Number of animals (only) | 30 | 30 | 30 | 30 |
| Liver glycogen content | 688.2±366.7 | 1074.5±207.8 | 1153.7±269.9 | 1256.5±555.2 |
| P values | 0.0069** | 0.0047** | 0.011* |
Note：* represent to compare with significant difference with control group.
* represents to compare with significant differences with control group.
The antifatigue mouse hepatic glycogen content of person in middle and old age's sports drink is shown：The glycogen of three dosage groups of person in middle and old age's sports drink
Former content is all remarkably higher than control group, and is examined through t, is respectively provided with statistical significance, illustrates person in middle and old age's sports drink to enhancing
The tolerance fatigue capability of mouse has remarkable result.
4th, result and discussion
By to 5% antifatigue zoopery of bearing a heavy burden, Serum lactic acid content, liver glycogen content this three indexs data system
Meter analysis, the mice burden swimming time is apparently higher than control group；Serum lactic acid content is significantly lower than control group；Hepatic glycogen content is obvious
There is statistical significance higher than control group, and through t inspections, therefore can be determined that there is person in middle and old age's sports drink raising mouse to resist
The effect of tired.
The embodiments of the present invention described above are not intended to limit the scope of the present invention.It is any in the present invention
Spirit and principle within the modifications, equivalent substitutions and improvements made etc., should be included in the claim protection model of the present invention
Within enclosing.
Claims (9)
- A kind of 1. person in middle and old age's sports drink containing marine oligosaccharide, it is characterised in that：Containing old in marine oligosaccharide described in per 1L Year sports drink includes the raw material of following weight：Chitosan oligosaccharide 0.1-2.0g, guarana extract 0.1-2.0g, taurine It is 0.01-0.2g, malic acid 0.05-2.0g, fructose 1.0-10.0g, xylitol 10.0-30.0g, zinc citrate 0.1-2.0mg, anti- Bad hematic acid 0.1-0.3g, citric acid 1.0-3.0g, potassium chloride 0.01-3g, magnesium sulfate 0.2-1.2g, sodium chloride 0.1-10.0g, its It is remaining to be supplied with distilled water.
- A kind of 2. person in middle and old age's sports drink containing marine oligosaccharide according to claim 1, it is characterised in that：Described in per 1L Person in middle and old age's sports drink containing marine oligosaccharide includes the raw material of following weight：Chitosan oligosaccharide 1.0g, guarana extract 2.0g, Taurine 0.15g, malic acid 0.1g, fructose 5.0g, xylitol 20.0g, zinc citrate 1.0mg, ascorbic acid 0.2g, citric acid 2.0g, potassium chloride 1.5g, magnesium sulfate 0.6g, sodium chloride 5g, remaining is supplied with distilled water.
- A kind of 3. person in middle and old age's sports drink containing marine oligosaccharide according to claim 1, it is characterised in that：Described in per 1L Person in middle and old age's sports drink containing marine oligosaccharide includes the raw material of following weight：Chitosan oligosaccharide 0.5g, guarana extract 0.5g, Taurine 0.15g, malic acid 0.1g, fructose 5.0g, xylitol 20.0g, zinc citrate 1.0mg, ascorbic acid 0.2g, citric acid 2.0g, potassium chloride 1.5g, magnesium sulfate 0.6g, sodium chloride 5g, remaining is supplied with distilled water.
- A kind of 4. person in middle and old age's sports drink containing marine oligosaccharide according to claim 1, it is characterised in that：Described in per 1L Person in middle and old age's sports drink containing marine oligosaccharide includes the raw material of following weight：Chitosan oligosaccharide 1.5g, guarana extract 1.0g, Taurine 0.15g, malic acid 0.1g, fructose 5.0g, xylitol 20.0g, zinc citrate 1.0mg, ascorbic acid 0.2g, citric acid 2.0g, potassium chloride 1.5g, magnesium sulfate 0.6g, sodium chloride 5g, remaining is supplied with distilled water.
- A kind of 5. person in middle and old age's sports drink containing marine oligosaccharide according to claim 1, it is characterised in that：Described in per 1L Person in middle and old age's sports drink containing marine oligosaccharide includes the raw material of following weight：Chitosan oligosaccharide 2.0g, guarana extract 1.5g, Taurine 0.15g, malic acid 0.1g, fructose 5.0g, xylitol 20.0g, zinc citrate 1.0mg, ascorbic acid 0.2g, citric acid 2.0g, potassium chloride 1.5g, magnesium sulfate 0.6g, sodium chloride 5g, remaining is supplied with distilled water.
- 6. according to a kind of any described person in middle and old age's sports drink containing marine oligosaccharide of claim 1 to 5, it is characterised in that： Deacetylation >=90% of the chitosan oligosaccharide.
- 7. according to a kind of any described person in middle and old age's sports drink containing marine oligosaccharide of claim 1 to 5, it is characterised in that： The average molecular weight of the chitosan oligosaccharide is 200~1000Da.
- 8. according to a kind of any described person in middle and old age's sports drink containing marine oligosaccharide of claim 1 to 5, it is characterised in that： Purity >=90% of the chitosan oligosaccharide.
- 9. according to a kind of any described person in middle and old age's sports drink containing marine oligosaccharide of claim 1 to 5, it is characterised in that： Guarana extractive content >=20%.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112546052A (en) * | 2020-12-28 | 2021-03-26 | 青岛博智汇力生物科技有限公司 | Composition containing marine oligosaccharide for preventing and treating gout |
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| CN1871948A (en) * | 2005-08-11 | 2006-12-06 | 黄恒燊 | Sport beverage and preparation method |
| CN104473278A (en) * | 2014-12-09 | 2015-04-01 | 青岛德润电池材料有限公司 | Vegetable health drink and preparation method thereof |
| CN104720048A (en) * | 2013-12-23 | 2015-06-24 | 无锡伟康生物科技有限公司 | Health beverage for relieving fatigue and improving immunity |
| CN106333207A (en) * | 2015-07-08 | 2017-01-18 | 惠州长龙生物技术有限公司 | Solid beverage containing chitosan oligosaccharide and preparation method thereof |
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2017
- 2017-11-07 CN CN201711085454.3A patent/CN107811181A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1871948A (en) * | 2005-08-11 | 2006-12-06 | 黄恒燊 | Sport beverage and preparation method |
| CN104720048A (en) * | 2013-12-23 | 2015-06-24 | 无锡伟康生物科技有限公司 | Health beverage for relieving fatigue and improving immunity |
| CN104473278A (en) * | 2014-12-09 | 2015-04-01 | 青岛德润电池材料有限公司 | Vegetable health drink and preparation method thereof |
| CN106333207A (en) * | 2015-07-08 | 2017-01-18 | 惠州长龙生物技术有限公司 | Solid beverage containing chitosan oligosaccharide and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112546052A (en) * | 2020-12-28 | 2021-03-26 | 青岛博智汇力生物科技有限公司 | Composition containing marine oligosaccharide for preventing and treating gout |
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