CN109475513A - The energy composition of lifting motion ability - Google Patents
The energy composition of lifting motion ability Download PDFInfo
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- CN109475513A CN109475513A CN201680086362.4A CN201680086362A CN109475513A CN 109475513 A CN109475513 A CN 109475513A CN 201680086362 A CN201680086362 A CN 201680086362A CN 109475513 A CN109475513 A CN 109475513A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P39/06—Free radical scavengers or antioxidants
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Abstract
A kind of composition and application thereof is disclosed, the composition is according to weight score, including following component: 1~500 part of astaxanthin；1~1000 part of sylvite；1~500 part of calcium salt；1~500 part of magnesium salts；1~5000 part of sodium salt, wherein, the astaxanthin includes but is not limited to food-grade haematococcus pluvialis and its extract, the sylvite includes but is not limited to food-grade potassium chloride, the sodium salt includes but is not limited to food grade sodium chloride, sodium carbonate, sodium bicarbonate, the magnesium salts includes but is not limited to food grade magnesium sulfate, and the calcium salt includes but is not limited to food-grade calcium carbonate.Above-mentioned composition, which is added to, to be had effects that in health care product and food that energy is augmented, improves the anti-fatigue ability in movement, and promote the rapid recovery of physical strength.
Description
The present invention relates to food, drug, health-related technical field of pharmaceuticals more particularly to it is antifatigue with it is tired after the food that restores and its application.
In normal life oxidation activity, incomplete oxidation occurs for organic compound to generate free radicals human body.Antioxidant system can effectively dispose free radical in normal condition servant's body, maintain body eubolism and free radical balance.However, in vigorous exercise or the mental activity of high concentration, since body runs at high speed, not only energy consumption is big, and metabolism energy supply needs to consume a large amount of oxygen in a short time, causes oxygen insufficient and incomplete oxidation occurs, thus will lead to the generation and accumulation of excessive free radical.
Have research to confirm: the metabolic activity beyond usual oxygen consumption 70%, which can produce, causes about 12 times of free radical to generate, when human body antioxidant system can not remove the free radical largely generated due to highly energy-consuming and high oxygen consumption state in time, these superfluous high mars free radicals can capture intracellular electronics, it causes the destruction of cell, mitochondria, DNA, hyaluronic acid etc., causes muscle tendon fatigue of joint, aches and inflammation.Therefore, it is necessary to supplement antioxidant, mitigate destruction of the free radical to cell mitochondrial DNA hyaluronic acid, eliminates fatigue to realize, prevention is ached and the purpose of inflammation.
Astaxanthin (astaxanthin) also known as astaxanthin, Astaxanthin are the oxidized derivatives of beta carotene, its chemical name is: 3,3 '-dihydroxy -4,4 '-diketo beta carotenes, molecular formula C40H52O4, molecular weight
It is 596.86.
Nature, astaxanthin have strongest inoxidizability.Its antioxidant activity is hundreds of or even thousands of times of vitamin E, is ascorbic thousands of times.Astaxanthin is widely present in the feather of living nature, especially shrimp, crab, fish, frond, yeast and birds.
Haematococcus pluvialis be it is current extract the best biology of natural astaxanthin, content is high, bioactivity is strong, it is safe and reliable, have no toxic side effect.Haematococcus pluvialis is put into Chinese new resource food catalogue on October 29th, 2010.
Electrolyte metabolism is very strong in movement, and electrolyte is largely lost with sweat.Electrolyte ingredient mainly includes sodium, potassium, calcium, magnesium and other microelements.When human body sodium depletion, hyponatremia and muscle cramp can be caused.Potassium deficiency will affect insulin secretion, cause sugar using limited, muscle blood flow amount reduction, and cause muscle inability and cardiac disorder.Calcium deficiency will cause bad osteoporosis, rickets, muscle function, muscle cramp, arrhythmia cordis.Magnesium shortage, which will affect sodium Potassium Metabolism balance, makes cardiac muscle cell's potassium deficiency, causes arrhythmia cordis, locomitivity declines to a great extent.In motion process/after, simple moisturizing can be further exacerbated by the unbalance of water-electrolyte metabolism, and therefore, the appropriate supplement electrolyte balance that not only contributes to maintain body fluid when moisturizing is also beneficial to keep optimal locomitivity.
Summary of the invention
The present invention is in view of the above-mentioned problems, provide the following technical solution:
The present invention provides a kind of compositions, and the composition is according to weight score, including following component: 1~500 part of astaxanthin；1~1000 part of sylvite；1~500 part of calcium salt；1~500 part of magnesium salts；1~5000 part of sodium salt.Wherein, the astaxanthin includes
But it is not limited to food-grade haematococcus pluvialis and its extract, the weight ratio of the haematococcus pluvialis and its extract is divided into its amount for containing comparable astaxanthin, and the sylvite includes but is not limited to food-grade potassium chloride, the sodium salt includes but is not limited to food grade sodium chloride, sodium carbonate, sodium bicarbonate, the magnesium salts include but is not limited to food grade magnesium sulfate, and the calcium salt includes but is not limited to food-grade calcium carbonate.
In one preferred embodiment of the invention, the composition further comprises: 1~100000 part of sugar；1~10000 part of vitamin C.
In one preferred embodiment of the invention, the composition is according to weight score, including following component: 1~400 part of astaxanthin；1~80000 part of sugar；1~500 part of potassium chloride；1~300 part of calcium carbonate；1~300 part of magnesium sulfate；1~5000 part of vitamin C；1~3000 part of sodium chloride,
Preferably, 1~100 part of astaxanthin；50~8000 parts of sugar；50~300 parts of potassium chloride；1~200 part of calcium carbonate；1~200 part of magnesium sulfate；1~3000 part of vitamin C；20~1000 parts of sodium chloride；It is furthermore preferred that 1~2 part of astaxanthin；50~700 parts of sugared part；50~120 parts of potassium chloride；1~20 part of calcium carbonate；2~40 parts of magnesium sulfate；1~200 part of vitamin C；30~800 parts of sodium chloride；Most preferably, 2 parts of astaxanthin；700 parts of sugar；120 parts of potassium chloride；20 parts of calcium carbonate；40 parts of magnesium sulfate；100 parts of vitamin C；750 parts of sodium chloride.
In one preferred embodiment of the invention, affiliated nutrition carbohydrate includes but is not limited to glucose, maltose, fructose and oligosaccharides in the composition；Including medicine and other acceptable possible optional carriers of food.
It also include caffeine in the composition in one preferred embodiment of the invention, the preferably described caffeine comes from coffee bean, the extracts such as Guarana and tea.
Invention also provides above-mentioned compositions to prepare the purposes in following food or drug, the purposes be to subject's applying said compositions after, improve the anti-fatigue ability in movement, and promote the rapid recovery of physical strength.
In one preferred embodiment of the invention, the dosage form of food is selected from tablet, capsule, pulvis, granule, effervescent agent, beverage, mixture or oral solution.
Invention additionally provides methods that is a kind of antifatigue and/or recovering from fatigue, and the method includes applying above-mentioned composition to subject.
Formula provided by the invention and purposes have many advantages, such as to significantly improve post exercise fatigue recovery and reduce inflammation to occur, regain one's strength rapidly, using simple, significant in efficacy.
In anti-Fatigue Composition of the present invention, each component passes through different approaches, the effect of collaboration, as energy matter and Auto-regulator collaboration promote synergy, enhance the antioxidant capacity of body, free radical is removed while supplementing energy substance, the metabolites such as lactic acid, to effectively play antifatigue effect, human body can be supplied rapidly due to movement, specifically under high-intensity exercise training, or body-building is when largely perspiring, the nutrient of consumed carbohydrate and loss, facilitate alleviation maincenter and skeletal strain, the anti-oxidant and aerobic metabolism for improving body is horizontal, improve the coefficient of oxygen utilization of cell, lactic acid is accumulated after reducing movement, reduce urea nitrogen numerical value after moving, the recovery of Fatique after Sports occurs and promotes for delay fatigue, promoting motion function facilitates the movement and the anti-fatigue ability that quickly improve body, avoid the hair of injury gained in sports It is raw.The composition is a kind of new compositions that can be obviously improved locomitivity.
Medicine or the acceptable carrier of food can be added in the composition of the application, be developed into preparation；The ingredient of " pharmaceutically acceptable " or " acceptable in bromatology " or " acceptable in health care conduct and learning ", refer specifically to have the substance of reasonable benefit/risk ratio suitable for people and/or animal and without excessive bad side reaction (such as toxicity, stimulation and allergy)." pharmaceutically acceptable carrier " refers to the carrier for Therapeutic Administration, including various excipient and diluent.The term refers to medicament carriers some in this way: themselves not being necessary active constituent, and does not have excessive toxicity after applying.For example the forms such as granule, oral solution, tablet, capsule, pill are made by pharmaceutical carrier, it is able to achieve using existing commercial process.Directly the raw material of composition can also be mixed, kneading raw material makes homogeneous body, then by roll forming, and is cut into the form of energy stick, finally vacuumizes packaging so that it is convenient to save and carry, can carry out energy supply when different as needed.Therefore, any that the possibility that composition carries out is corrected by increasing or decreasing above-mentioned carrier, all refer to the present application protection scope.
It below will the present invention is further described in detail according to specific embodiment.
Embodiment 1: the effervesce tablet raw material includes following components by weight: 2 parts of astaxanthin, 700 parts, 120 parts of potassium chloride, 20 parts of calcium carbonate, 40 parts of magnesium sulfate, 100 parts of vitamin C, 750 parts of sodium chloride of sugar.The embodiment uses 100 parts of 2% haematococcus pluvialis microcapsule powder of astaxanthin-containing (2 parts of astaxanthin-containing).By haematococcus pluvialis extract after embedding manufactured water dispersible microscapsule powder, and effervescent tablet is made using powder particle as the raw material addition effervescent agents such as sodium bicarbonate citric acid, this form fully dispersed can be dissolved into aqueous solution, and be conducive to absorption of human body.The raw material is commercially available, and is food-grade.Used preparation method is field of food well-known technique.
Embodiment 2: the effervesce tablet raw material includes following components by weight: 10 parts of astaxanthin, 800 parts of sugar, and 160 parts of potassium chloride, 40 parts of calcium carbonate, 80 parts of magnesium sulfate, 600 parts of vitamin C, 800 parts of sodium chloride,.Effervescent tablet is using the method preparation in embodiment 1.
Embodiment 3: the effervesce tablet raw material includes following components by weight: 8 parts of astaxanthin, 50 parts, 50 parts of potassium chloride, 1 part of calcium carbonate, 2 parts of magnesium sulfate, 800 parts of vitamin C, 20 parts of sodium chloride of sugar.Effervescent tablet is using the method preparation in embodiment 1.
Embodiment 4: the effervesce tablet raw material includes following components by weight: 6 parts of astaxanthin, 600 parts, 180 parts of potassium chloride, 80 parts of calcium carbonate, 1 part of magnesium sulfate, 1000 parts of vitamin C, 30 parts of sodium chloride of sugar.Effervescent tablet is using the method preparation in embodiment 1.
Embodiment 5: the effervesce tablet raw material includes following components by weight: 1 part of astaxanthin, 10 parts, 1 part of potassium chloride, 100 parts of calcium carbonate, 100 parts of magnesium sulfate, 1 part of vitamin C, 1000 parts of sodium chloride of sugar.Effervescent tablet is using the method preparation in embodiment 1.
After effervescent tablet in the application can move during exercise, antioxidant is replenished in time, which can also be applied to other carriers and preparation or solution is made, and can be added in the health care product and food of supplement energy.It is ionized under the action of water by the way that effervescent tablet is distinctive, generates a large amount of carbon dioxide, so that tablet is disintegrated and melts rapidly, astaxanthin can be allowed to disperse to be evenly distributed with rapidly in the solution, uniformly mixed solution is formed, absorption of human body is more conducive to, realizes the purpose of rapid-onset.
It is the inspection effervescent tablet for supplementing antioxidant and electrolyte during moving of the invention to the sportive recovery from fatigue effect of sport people, has carried out following experiment:
1, subject material: being to negative product in the same old way with equal heats glucose water in equal volume using effervescent tablet obtained in Examples 1 to 5 as laboratory sample；
2, study subject: selection pulse is close, and nearly 5 kilometers of races achievement, recent drill program, moon race amount and nearest 30 kilometers of achievements are that conditional filtering goes out to run friendly 200 people participation experiment.5 groups are randomly divided into, is randomly divided into experimental group and control group, every group of 20 people in every group again.Experiment the last fortnight starts to take a made aqueous solution 500ml of laboratory sample, until experiment terminates.Study subject maintains full diet, does not take other nutritional supplements；
3, experimental method: with certain marathon for formal experimental day, experimental subjects, which need to do the best, to be run through using creating personal best record as target, on the way such as discomfort, can be abandoned.It collects morning on the same day and wins (pulse after early morning wake up) and next day, morning third day rich data.Data variation was won to determine fatigue recovery degree relative to match morning on the same day with the data of next day and three days.
Recovery extent criterion:
Restore morning completely to win relative to match morning on the same day rich difference in 5 times；
Restore morning and win relative to match morning on the same day rich difference in 10 times in part；
Do not restore morning to win relative to match morning on the same day rich difference at 10 times or more.
4, implementation result: (recovery rate only with it is complete restore morning it is rich calculate)
As a result it can be seen that through one-way analysis of variance
Under the formula of embodiment 2~4, in second to the 5th group, experimental group next day complete recovery rate is averagely about 62%, and third day, complete recovery rate was averagely about 90%；And control group next day complete recovery rate is averagely about 25%, third per day about 75% is restored completely, and the effect to recover from fatigue is significant (p < 0.05).
Especially under the formula of embodiment 1, in accordance with the present invention it has now surprisingly been found that, which has effects that extremely significant antifatigue and regains one's strength.Next day recovery rate is about 73%, third day recovery rate be about 100%, can extremely significant (p < 0.01) improve post exercise fatigue recovery and promote regain one's strength rapidly.
Embodiment 6: according to the composite formula ratio of Examples 1 to 5, preparing the liquid motion beverage of different content ratio respectively, wherein the available haematococcus pluvialis extract replacement containing same amount of astaxanthin, and the form of beverage is normal most useful for absorption of human body
The energy means for the lifting motion ability seen.The raw material is commercially available, and is food-grade.Used method for preparing beverage is the well-known technique of field of foodstuff beverage.
Sports drink in embodiment 6 is in the above way applied to the study subject for five groups of similarity conditions being equally grouped, discovery the composition beverage in this five groups equally plays the role of antifatigue well and/or recovers from fatigue.It is especially 2 parts of astaxanthin in formula rate；30000 parts of sugar；120 parts of potassium chloride；20 parts of calcium carbonate；40 parts of magnesium sulfate；100 parts of vitamin C；At 750 parts of sodium chloride, it was surprisingly found now that the formula has effects that extremely significant antifatigue and regains one's strength.Next day recovery rate is about 74%, third day recovery rate be about 100%, can extremely significant (p < 0.01) improve post exercise fatigue recovery and promote regain one's strength rapidly.
Embodiment 7: according to the composite formula ratio of Examples 1 to 5, the liquid motion beverage of different content ratio is prepared respectively, the wherein available haematococcus pluvialis extract replacement containing same amount of astaxanthin, and caffeine is added, or when coffee bean containing considerable amount of caffeine, and the effervescent tablet in embodiment 7 is in the above way applied to the study subject for five groups of similarity conditions being equally grouped, effect is administered to compared to not adding caffeine, better effect.
Above-mentioned experiment show composition of the invention be highly suitable for movement during fatigue recovery, ensure that the persistence and endurance of movement, to improve sports achievement, have facilitation.The composition is a kind of new energy composition that can be obviously improved locomitivity
It is described above, it is only present pre-ferred embodiments, it is not intended to limit the present invention in any form, although the present invention is disclosed above in the preferred embodiment, however, it is not intended to limit the invention, any person skilled in the art, without departing from the scope of the present invention, when the technology contents using the disclosure above make a little change or are modified to equivalent
The equivalent embodiment of variation, but without departing from the technical solutions of the present invention, technology refers to any simple modification, equivalent change and modification to the above embodiments according to the present invention, belongs in the range of technical solution of the present invention.
Claims (8)
- A kind of composition, which is characterized in that the composition firmly will include following component: 1~500 part of astaxanthin according to weight score；1~1000 part of sylvite；1~500 part of calcium salt；1~500 part of magnesium salts；1~5000 part of sodium salt, wherein, the astaxanthin includes but is not limited to food-grade haematococcus pluvialis and its extract, the weight ratio of the haematococcus pluvialis and its extract is divided into its amount for containing comparable astaxanthin, and the sylvite includes but is not limited to food-grade potassium chloride, and the sodium salt includes but is not limited to food grade sodium chloride, sodium carbonate, sodium bicarbonate, the magnesium salts include but is not limited to food grade magnesium sulfate, and the calcium salt includes but is not limited to food-grade calcium carbonate.
- Composition according to claim 1, which is characterized in that the composition further include: 1~100000 part of sugar；1~10000 part of vitamin C.
- Composition according to claim 2, which is characterized in that the composition is according to weight score, including following component: 1~400 part of astaxanthin；1~80000 part of sugar；1~500 part of potassium chloride；1~300 part of calcium carbonate；1~300 part of magnesium sulfate；1~5000 part of vitamin C；1~3000 part of sodium chloride,Preferably, 1~100 part of astaxanthin；50~8000 parts of sugar；50~300 parts of potassium chloride；1~200 part of calcium carbonate；1~200 part of magnesium sulfate；1~3000 part of vitamin C；20~1000 parts of sodium chloride；It is furthermore preferred that 1~2 part of astaxanthin；50~700 parts of sugared part；50~120 parts of potassium chloride；1~20 part of calcium carbonate；2~40 parts of magnesium sulfate；1~200 part of vitamin C；30~800 parts of sodium chloride；Most preferably, 2 parts of astaxanthin；700 parts of sugar；120 parts of potassium chloride；20 parts of calcium carbonate；40 parts of magnesium sulfate；100 parts of vitamin C；750 parts of sodium chloride.
- Composition described according to claim 1~any one of 3, which is characterized in that carbohydrate described in the composition includes But it is not limited to glucose, maltose, fructose and oligosaccharides；It optionally include medicine and/or the acceptable carrier of food.
- According to the composition for asking any one of 1~3, which is characterized in that also include caffeine in the composition, the preferably described caffeine is from extracts such as coffee bean, Guarana and tea.
- After subject's applying said compositions, the anti-fatigue ability in movement can be improved, and promote the rapid recovery of physical strength it is characterized in that, be used to prepare in the food or drug of following effect, and commercialize in the composition of any one of Claims 1 to 5.
- The composition that Claims 1 to 5 is one correlated product produced, including but not limited to tablet, capsule, pulvis, granule, effervescent agent, beverage, mixture or oral solution, beverage.
- Method that is a kind of antifatigue and/or recovering from fatigue, the method includes the composition of any one of Claims 1 to 5 is applied to subject.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2016/083942 WO2017206026A1 (en) | 2016-05-30 | 2016-05-30 | Energy composition for enhancing athletic ability |
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| CN109475513A true CN109475513A (en) | 2019-03-15 |
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| CN201680086362.4A Pending CN109475513A (en) | 2016-05-30 | 2016-05-30 | The energy composition of lifting motion ability |
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| WO (1) | WO2017206026A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112931740A (en) * | 2021-04-08 | 2021-06-11 | 云南爱尔康生物技术有限公司 | Haematococcus pluvialis natural sports beverage and preparation method thereof |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109198621A (en) * | 2018-09-30 | 2019-01-15 | 徐州统食品工业有限公司 | A kind of composition and preparation method thereof that locomitivity can be improved |
| US20220152135A1 (en) * | 2019-03-03 | 2022-05-19 | Algatechnologies Ltd. | Compositions comprising algae powder and uses thereof |
| CN111972586A (en) * | 2020-08-17 | 2020-11-24 | 同方药业集团有限公司 | Astaxanthin nutrient solid beverage |
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| JP2006347927A (en) * | 2005-06-14 | 2006-12-28 | Fuji Chem Ind Co Ltd | Fatigue-improving agent |
| CN101243896A (en) * | 2008-03-05 | 2008-08-20 | 宁波大学 | Shrimp beverage and preparation thereof |
| CN105193842A (en) * | 2015-11-05 | 2015-12-30 | 阿士力(深圳)运动健康科技有限公司 | Effervescent tablets capable of supplementing antioxidant and application of effervescent tablets |
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2016
- 2016-05-30 WO PCT/CN2016/083942 patent/WO2017206026A1/en active Application Filing
- 2016-05-30 CN CN201680086362.4A patent/CN109475513A/en active Pending
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| JP2006347927A (en) * | 2005-06-14 | 2006-12-28 | Fuji Chem Ind Co Ltd | Fatigue-improving agent |
| CN101243896A (en) * | 2008-03-05 | 2008-08-20 | 宁波大学 | Shrimp beverage and preparation thereof |
| CN105193842A (en) * | 2015-11-05 | 2015-12-30 | 阿士力(深圳)运动健康科技有限公司 | Effervescent tablets capable of supplementing antioxidant and application of effervescent tablets |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112931740A (en) * | 2021-04-08 | 2021-06-11 | 云南爱尔康生物技术有限公司 | Haematococcus pluvialis natural sports beverage and preparation method thereof |
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| WO2017206026A1 (en) | 2017-12-07 |
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