CN103766736B - Antifatigue energy composition and application thereof - Google Patents

Antifatigue energy composition and application thereof Download PDF

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CN103766736B
CN103766736B CN201410027115.XA CN201410027115A CN103766736B CN 103766736 B CN103766736 B CN 103766736B CN 201410027115 A CN201410027115 A CN 201410027115A CN 103766736 B CN103766736 B CN 103766736B
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parts
extract
energy composition
powder
antifatigue
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CN103766736A (en
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陈卡
周永
刘鹏
易龙
常徽
朱俊东
糜漫天
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Third Military Medical University TMMU
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A23L29/35—Degradation products of starch, e.g. hydrolysates, dextrins; Enzymatically modified starches
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/185—Vegetable proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10—Cereal-derived products
    • A23L7/161—Puffed cereals, e.g. popcorn or puffed rice
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The present invention discloses a kind of antifatigue energy composition, energy composition raw material parts by weights comprises expanded black rice powder, oatmeal, coconut oil, corn syrup, soybean isolate protein powder, maltodextrin, carnitine, vine tea flavone extract, grape seed extract, Quercetin extract, n-octacosanol, caffeine, branched-chain amino acid, taurine, low fat cocoa powder, vanilla, the sugar required for body can be supplemented fast, fat and protein and electrolyte are with other nutrients and promote the absorption of nutrition, human body can be supplemented rapidly due to motion, specifically in, high strength body-building, and under training condition a large amount of perspiration and consume carbohydrate with loss nutrient, contribute to alleviation maincenter and periphery fatigue, improve oxidation resistance and the aerobic metabolism level of body, improve the coefficient of oxygen utilization of cell, contribute to the motion and the anti-fatigue ability that improve body fast, avoid the generation of injury gained in sports.

Description

Antifatigue energy composition and application thereof
Technical field
The present invention relates to a kind of composition, particularly a kind of antifatigue energy composition and application thereof.
Background technology
Exercise induced fatigue refers to the physiological phenomenon of kinetic muscle maximum collapse or the temporary decline of peak power output.Kinetism decline is basic sign and the intrinsic propesties of exercise induced fatigue.Since this century, researcher has carried out large quantifier elimination from different angles to exercise induced fatigue, proposing the negative effect that exercise stress metabolism strengthens may be the basic reason that exercise induced fatigue occurs, as the exhaustion of metabolism matrix, the accumulation of metabolite, the acidifying of metabolism environment.They may cause the change of Fiber structure integrality, energy supply, neurohumor adjustment etc. by multiple channel, cause motion contraction of muscle and diastolic dysfunction.For example, when long muscle activity causes muscle function to decline, decline when strength speed is equal to, so when completing training, often unable to do what one wishes and feel tired; Again in endurance exercise, if cardio-pulmonary function declines, the ability of bearing load endurance will reduce, and body will be tired and reduce ability to work.When human body to be engaged in when motion causes fatigue often in comitative aspect energy substance consume in a large number, as maximal exercise 2-3 minute to time very tired, intramuscular phosphocreatine can be down to nadir; In long persistent movement, due to a large amount of consumption of sugar, Body development and blood sugar all decline.The consumption of energy reserves and minimizing, can cause the reduction of each organ dysfunction.In addition the impact such as accumulation and water-electrolyte metabolism change of metabolite during muscle activity, body ability to work will decline and occur fatigue.
In motion process, human body energy consumption increases severely, therefore, the supplementary of energy substance ensures that human body energy balance is necessary, simultaneously, in the energy metabolism of fierceness, many enzymes, hormone, blood active ingredient etc. also participate in energetic supersession and O_2 transport, so many adjustment nutrients (vitamin, mineral matter etc.) are also along with consumption.What first need after motion to supplement is exactly energy substance, mainly sugar and fat and protein.
Carbohydrate is the important energy substance of body, is also the energy first utilized in motion process.Body storage carbohydrates is limited, when blood sugar and glycogen deposit are exhausted, will cause tired generation.Supplement before motion appropriate carbohydrate delay fatigue occur confirm by many results of study, and to be used widely.Sportsman can produce good antifatigue effect supplement the beverage containing 6% carbohydrate before motion after, shows as large intensity and runs to the power time that exhausts and obviously extend.Strenuous exercise to power exhausts rear supplementary carbohydrate and can reduce body and utilize muscle glycogen speed, avoids motion process glycogen to consume excessively, and can maintain blood sugar concentration in higher level.
Lipid, motion process skeletal muscle mainly relies on carbohydrate and fat oxidation provides energy, increase exercise intensity to cause carbohydrate to utilize increasing, glycogen degradation supplements the deficiency of carbohydrate, and the limited glycogen deposit of body has just become the limiting factor determining body endurance.Much nutritional intervention research is devoted to break through this bottleneck.Increase fatty acid oxidation in motion process and effectively can reduce glycogen degradation, thus strengthen exercise tolerance.Medium chain triglyceride (MCT) is made up of the medium chain fatty acid of 6 ~ 12 carbon atoms, is mainly present in coconut oil or palm oil.MCT with medium chain fatty acid form absorbed into serum, its metabolism and glucose soon about the same, and its energy density is 2 times of carbohydrate, and many researchers think that MCT improves body movement ability, delay fatigue process by saving glucose.MCT supplements and general advocates in the long period with comparatively before strenuous exercise, as before the time trial of 20km bicycle, 2 ~ 4 weeks supplement medium chain fatty acid, human body energy metabolic process can be improved, improve body fat acid oxidase ability, reduce body glucose consumption, thus delay fatigue occurs, improve sports achievement.
Protein, the metabolism of motion process human body energy increases sharply, to the corresponding raising of the demand of protein.Endurance training process is supplemented lactalbumin and can be synthesized by stimulated muscle histone, and troponin and myosinogen content have remarkable increase, and muscle cross sections is long-pending to be increased, and muscular strength is strengthened, and alleviates the rear damage of motion and DOMS, significantly improves training effect.Protein uptake is not enough, and body immunity can be caused to decline, and then makes human body often feel fatigue etc.
Especially in military training in the army process, the tired raising that not only can have influence on training achievement, excessive fatigue also can damage the multiple systems such as muscle systems, cardiovascular system, nervous system, internal system of body, causes the symptoms such as appetite reduction, Body weight loss, sleep-disorder.In daily workout, the training of large intensity for a long time makes body be difficult to bear, and finally causes major injury to body.And when body carries out manual labor, heart rate increases, cardiac output is increased, thus the demand of metabolism when meeting body work.But heart rate increase can make heart acting increase, human body energy consumption increases, and then affects body labour capacity, especially under altitude environment, more obvious on the impact of labour capacity.
Summary of the invention
In view of this, the object of the present invention is to provide a kind of antifatigue energy composition and application thereof, sugar, fat and protein required for body and electrolyte and other nutrients can be supplemented fast, improve the anti-oxidant and aerobic metabolism level of body, improve the coefficient of oxygen utilization of cell, contribute to the motion and the anti-fatigue ability that improve body fast, avoid the generation of injury gained in sports.
A kind of antifatigue energy composition of the present invention, energy composition raw material comprises following component by weight: expanded black rice powder 150-400 part, oatmeal 150-400 part, coconut oil 20-100 part, corn syrup 100-300 part, soybean isolate protein powder 20-150 part, maltodextrin 100-300 part, carnitine 1-30 part, vine tea flavone extract 1-30 part, grape seed extract 1-30 part, Quercetin extract 1-30 part, n-octacosanol 0.001-0.1 part, caffeine 0.01-0.5 part, branched-chain amino acid 10-40 part, taurine 10-40 part, low fat cocoa powder 10-40 part, vanilla 0.1-0.8 part,
Further, expanded black rice powder 200-300 part, oatmeal 200-300 part, coconut oil 40-80 part, corn syrup 120-250 part, soybean isolate protein powder 40-120 part, maltodextrin 150-200 part, carnitine 1-20 part, vine tea flavone extract 1-20 part, grape seed extract 1-20 part, Quercetin extract 1-20 part, n-octacosanol 0.001-0.003 part, caffeine 0.01-0.5 part, branched-chain amino acid 10-20 part, taurine 10-20 part, low fat cocoa powder 10-20 part, vanilla 0.1-0.6 part;
Further, expanded black rice powder 200-260 part, oatmeal 200-260 part, coconut oil 40-80 part, corn syrup 120-200 part, soybean isolate protein powder 40-100 part, maltodextrin 150-180 part, carnitine 1-10 part, vine tea flavone extract 1-10 part, grape seed extract 1-10 part, Quercetin extract 1-10 part, n-octacosanol 0.001-0.003 part, caffeine 0.01-0.5 part, branched-chain amino acid 10-20 part, taurine 10-20 part, low fat cocoa powder 10-20 part, vanilla 0.1-0.6 part;
Further, 250 parts, expanded black rice powder, oatmeal 250 parts, coconut oil 60 parts, corn syrup 130 parts, soybean isolate protein powder 60 parts, maltodextrin 170 parts, carnitine 5 parts, vine tea flavone extract 5 parts, grape seed extract 5 parts, Quercetin extract 5 parts, n-octacosanol 0.003 part, caffeine 0.5 part, branched-chain amino acid 13 parts, taurine 16 parts, low fat cocoa powder 16 parts, vanilla 0.3 part.
Further, can be added one or more for improving or treat the Chinese medicine of accompanying symptoms when this energy composition uses;
Further, this energy composition can add the pharmaceutical carrier that medical science or bromatology or health care conduct and learning can accept and makes preparation;
The present invention also discloses a kind of antifatigue energy composition and is preparing the application in anti-fatigue medicament, anti-fatigue health-product containing, antifatigue food.
The extracting method of vine tea flavone extract, grape seed extract, Quercetin extract all adopts ordinary skill in the art means to extract (as lixiviate), also can direct outsourcing finished product, all can reach object of the present invention.
Beneficial effect of the present invention: the black rice in the present composition can improve immunity and hypoxia-bearing capability, its black rice pigments contained, belongs to tree peony anthocyanins, has facilitation to increase animal physique.
Containing abundant vitamin B1, B2, E, folic acid etc. in oat, blood circulation can be improved, release the pressure.
Carnitine plays basic effect to being become the process of ATP energy by fatty acid oxidation; Carnitine can promote the generation of ketone element, and this can play saving glucose, the effect of glycogen and protein, thus avoids muscle to degrade.The secretory volume of carnitine becomes with exercise intensity, and when high pressure training, it can ensure the adverse effect of body from hyperammonemia.
Containing dibydro myricetrin in vine tea flavone extract, under hypobaric hypoxia environment, lactic acid in serum can be reduced pile up and reduce LDH and BUN content, strengthen skeletal muscle mitochondrial respiratory chain complex enzyme (I, IV, V) active, by the exercise tolerance regulating the biosynthesis of skeletal muscle Mitochondria to strengthen body.
OPC in grape seed extract is good antioxidant, hydrogen atom can be supplied to oxygen radical and alicyclic diradical by the phenolic hydroxyl group that its molecular structure exists, free radical itself transfers non-free radical to, the peroxidating of polyunsaturated fatty acid on the biomembrane that blocking-up free radical causes, be conducive to the removing of active oxygen, body lipoid peroxidization resistant is strengthened, reduces the generation of free radical during motion and the damaging action to tissue thereof, the generation of effective delay fatigue.
N-octacosanol has the function improving glycogen accumulating capability and reduce BUN; there is certain cytoprotection; and there is the effect of resisting kinetic fatigue, enhance tolerance, energy and muscle power; the more important thing is that also having anti anoxia does; the lower tolerance of body at airtight anoxia, cerebrum ischemia anoxic and myocardial anoxia can be improved; the amount of oxyhemoglobin in motion artery blood can be increased, improve the deposit of oxygen in blood, thus improve the labour capacity of Human at High Altitude.
Branched-chain amino acid is the essential amino acid in body, is not only energy supply material, and can affect aromatic amino acid and enter brain, is a kind of important nutritional supplement.Comprise the amino acid that leucine, isoleucine, valine etc. have branched carbon skeleton.Branched-chain amino acid is catabolism in muscle mainly, has the effect of easy oxidized energy supply.Supplement branched-chain amino acid in training and not only have regulating action to the protein metabolism of skeletal muscle, cardiac muscle; and have protection and repair to its damage, after can promoting exhausted movemeat, namely convalescent gluconeogenesis, delay fatigue occur and promote the recovery of Fatique after Sports.Can the lipid bilayer stability of available protecting mitochondrial membrane, increase the mobility of mitochondrial membrane, ensure the normal performance of the biological function of mitochondrial membrane.Supplementing branched-chain amino acid by removing the radical chain reaction of crossing polyradical or blocking on mitochondrial membrane generated, the anti-oxidation function of protection ischemic myocardium, to make on film unrighted acid from the attack of free radical.Branched-chain amino acid can participate in the energy supply of long-time persistent movement, reduces the consumption of muscle glycogen, promotes the synthesis of muscle protein.Simultaneously supplemented with exogenous branched-chain amino acid can reduce that kinetic activity of serum enzyme increases, lipid peroxidation and prevent the generation of calcium overload, to resist periphery fatigue.
Taurine can be combined with insulin receptor; promote that musculature is to the picked-up of glucose, essential amino acid and utilization; accelerate glycolysis; increase gluconeogenesis; taurine is easy to absorb in stomach, has no side effect, and can not bring health hazard factor to Exercise Mechanics; SOD activity in Exercise Mechanics can be improved and effectively reduce MDA content, in antifatigue motion, raising locomitivity etc., having significant effect.
Antifatigue energy composition of the present invention and application thereof, each component passes through different approaches, collaborative effect, as energy matter and Auto-regulator collaborative promotion synergy, under collaborative promotion synergy between the nutrients such as branched-chain amino acid and other amino acid, strengthen the antioxidant capacity of body, scavenging free radicals while supplementary energy substance, the metabolites such as lactic acid, thus effectively play the effect of antifatigue, the sugar required for body can be supplemented fast, fat and protein and electrolyte are with other nutrients and promote the absorption of nutrition, human body can be supplied rapidly due to motion, specifically high-intensity exercise training under and body-building time perspire in a large number and consume carbohydrate with loss nutrient, contribute to alleviation maincenter and skeletal strain, improve the anti-oxidant and aerobic metabolism level of body, improve the coefficient of oxygen utilization of cell, after reducing motion, lactic acid is piled up, reduce the rear urea nitrogen numerical value of motion, delay fatigue occurs and promotes the recovery of Fatique after Sports, promote motion function and contribute to the motion and the anti-fatigue ability that improve body fast, avoid the generation of injury gained in sports.Antifatigue energy composition of the present invention, be not less than 39g containing total reducing sugar in every 60g, fat is not less than 6.5g, and protein is not less than 8.3g, and gross energy is not less than 210kcal.
Accompanying drawing explanation
Fig. 1 is the running Annual distribution of each group of rat test;
Fig. 2 is the random blood sugar value of each group of rat test;
Fig. 3 is the urea value of each group of rat test;
Fig. 4 is the creatine kinase value of each group of rat test;
Fig. 5 is the lactic dehydrogenase enzyme values of each group of rat test.
Detailed description of the invention
The antifatigue energy composition of the present embodiment, energy composition raw material comprises following component by weight: expanded black rice powder 150-400 part, oatmeal 150-400 part, coconut oil 20-100 part, corn syrup 100-300 part, soybean isolate protein powder 20-150 part, maltodextrin 100-300 part, carnitine 1-30 part, vine tea flavone extract 1-30 part, grape seed extract 1-30 part, Quercetin extract 1-30 part, n-octacosanol 0.001-0.1 part, caffeine 0.01-1 part, branched-chain amino acid 10-40 part, taurine 10-40 part, low fat cocoa powder 10-40 part, vanilla 0.1-0.8 part.
In the present embodiment, energy composition raw material comprises following component by weight: expanded black rice powder 200-300 part, oatmeal 200-300 part, coconut oil 40-80 part, corn syrup 120-250 part, soybean isolate protein powder 40-120 part, maltodextrin 150-200 part, carnitine 1-20 part, vine tea flavone extract 1-20 part, grape seed extract 1-20 part, Quercetin extract 1-20 part, n-octacosanol 0.001-0.003 part, caffeine 0.1-0.8 part, branched-chain amino acid 10-20 part, taurine 10-20 part, low fat cocoa powder 10-20 part, vanilla 0.1-0.6 part.
In the present embodiment, energy composition raw material comprises following component by weight: expanded black rice powder 200-260 part, oatmeal 200-260 part, coconut oil 40-80 part, corn syrup 120-200 part, soybean isolate protein powder 40-100 part, maltodextrin 150-180 part, carnitine 1-10 part, vine tea flavone extract 1-10 part, grape seed extract 1-10 part, Quercetin extract 1-10 part, n-octacosanol 0.001-0.003 part, caffeine 0.1-0.8 part, branched-chain amino acid 10-20 part, taurine 10-20 part, low fat cocoa powder 10-20 part, vanilla 0.1-0.6 part.
In the present embodiment, energy composition raw material comprises following component by weight: 250 parts, expanded black rice powder, oatmeal 250 parts, coconut oil 60 parts, corn syrup 130 parts, soybean isolate protein powder 60 parts, maltodextrin 170 parts, carnitine 5 parts, vine tea flavone extract 5 parts, grape seed extract 5 parts, Quercetin extract 5 parts, n-octacosanol 0.003 part, caffeine 0.5 part, branched-chain amino acid 13 parts, taurine 16 parts, low fat cocoa powder 16 parts, vanilla 0.3 part.
In the present embodiment, when this energy composition uses, can be added one or more for improving or treat the Chinese medicine of accompanying symptoms.
In the present embodiment, this energy composition can add the pharmaceutical carrier that medical science can accept and make preparation.
The antifatigue energy composition of the present embodiment is preparing the application in anti-fatigue medicament, anti-fatigue health-product containing, antifatigue food.
Below specific embodiments of the invention.
Embodiment one
The antifatigue energy composition of the present embodiment, energy composition raw material comprises following component by weight: 250 parts, expanded black rice powder, oatmeal 250 parts, coconut oil 60 parts, corn syrup 130 parts, soybean isolate protein powder 60 parts, maltodextrin 170 parts, carnitine 5 parts, vine tea flavone extract 5 parts, grape seed extract 5 parts, Quercetin extract 5 parts, n-octacosanol 0.003 part, caffeine 0.5 part, branched-chain amino acid 13 parts, taurine 16 parts, low fat cocoa powder 16 parts, vanilla 0.3 part.
Embodiment two
The antifatigue energy composition of the present embodiment, energy composition raw material comprises following component by weight: 150 parts, expanded black rice powder, oatmeal 150 parts, coconut oil 20 parts, corn syrup 100 parts, soybean isolate protein powder 20 parts, maltodextrin 100 parts, carnitine 1 part, vine tea flavone extract 1 part, grape seed extract 1 part, Quercetin extract 1 part, n-octacosanol 0.001 part, caffeine 0.01 part, branched-chain amino acid 10 parts, taurine 10 parts, low fat cocoa powder 10 parts, vanilla 0.1 part.
Embodiment three
The antifatigue energy composition of the present embodiment, energy composition raw material comprises following component by weight: 200 parts, expanded black rice powder, oatmeal 300 parts, coconut oil 40 parts, corn syrup 250 parts, soybean isolate protein powder 40 parts, maltodextrin 200 parts, carnitine 1 part, vine tea flavone extract 20 parts, grape seed extract 15 parts, Quercetin extract 15 parts, n-octacosanol 0.003 part, caffeine 0.5 part, branched-chain amino acid 15 parts, taurine 20 parts, low fat cocoa powder 10 parts, vanilla 0.5 part.
Embodiment four
The antifatigue energy composition of the present embodiment, energy composition raw material comprises following component by weight: 260 parts, expanded black rice powder, oatmeal 230 parts, coconut oil 80 parts, corn syrup 150 parts, soybean isolate protein powder 100 parts, maltodextrin 150 parts, carnitine 10 parts, vine tea flavone extract 10 parts, grape seed extract 10 parts, Quercetin extract 10 parts, n-octacosanol 0.002 part, caffeine 0.1 part, branched-chain amino acid 20 parts, taurine 18 parts, low fat cocoa powder 20 parts, vanilla 0.6 part.
Embodiment five
The antifatigue energy composition of the present embodiment, energy composition raw material comprises following component by weight: 400 parts, expanded black rice powder, oatmeal 400 parts, coconut oil 100 parts, corn syrup 300 parts, soybean isolate protein powder 150 parts, maltodextrin 300 parts, carnitine 30 parts, vine tea flavone extract 30 parts, grape seed extract 30 parts, Quercetin extract 30 parts, n-octacosanol 0.1 part, caffeine 0.05 part, branched-chain amino acid 40 parts, taurine 40 parts, low fat cocoa powder 40 parts, vanilla 0.8 part.
Embodiment six
The antifatigue energy composition of the present embodiment, energy composition raw material comprises following component by weight: 300 parts, expanded black rice powder, oatmeal 300 parts, coconut oil 80 parts, corn syrup 250 parts, soybean isolate protein powder 120 parts, maltodextrin 200 parts, carnitine 20 parts, vine tea flavone extract 20 parts, grape seed extract 20 parts, Quercetin extract 20 parts, n-octacosanol 0.003 part, caffeine 0.8 part, branched-chain amino acid 20 parts, taurine 20 parts, low fat cocoa powder 20 parts, vanilla 0.6 part.
Embodiment seven
The energy composition of the present embodiment, raw material comprises following component by weight: 230 parts, expanded black rice powder, oatmeal 200 parts, coconut oil 30 parts, corn syrup 170 parts, soybean isolate protein powder 40 parts, maltodextrin 180 parts, carnitine 8 parts, vine tea flavone extract 3 parts, grape seed extract 5 parts, Quercetin extract 2 parts, n-octacosanol 0.0015 part, caffeine 0.08 part, branched-chain amino acid 15 parts, taurine 17 parts, low fat cocoa powder 15 parts, vanilla 0.4 part.
The composition of above embodiment, when not affecting this composition effect, can add one or more for improving or treat the Chinese medicine of accompanying symptoms.
Said composition can add the pharmaceutical carrier that medical science can accept and make preparation; The composition of " pharmaceutically acceptable " or " acceptable in bromatology " or " health care conduct and learning on acceptable " is applicable to people and/or animal and without excessive bad side reaction (as toxicity, stimulation and allergy), namely has the material of rational benefit/risk ratio." pharmaceutically acceptable carrier " refers to the carrier being used for the treatment of agent administration, comprises various excipient and diluent.This term refers to some medicament carriers like this: they itself are not necessary active component, and do not have undue toxicity after using.Make the forms such as granule, oral liquid, tablet, capsule, pill as by pharmaceutical carrier, adopt existing commercial process all can realize.Also can directly be mixed by the raw material of composition, kneading raw material makes it to become homogeneous body, then passes through roll forming, and be cut into the form of energy stick, finally vacuumize packaging, so conveniently preserve and carry, energy supply can be carried out as required in different.
The energy composition that the invention also discloses above embodiment is preparing the application in anti-fatigue medicament, anti-fatigue health-product containing, antifatigue food; That is, this Chinese medicine composition can take the method for any prior art, and adds other composition any, for the preparation of anti-fatigue medicament, anti-fatigue health-product containing, antifatigue food.
Antifatigue effect test:
This test is through the agreement of ethics meeting, and 28 volunteers have participated in this double blinding, at random, and the experiment of parallel control.1. before the experiments, volunteer is arranged to test height, body weight, body-mass index, body fat content percentage, and maximal oxygen uptake.Maximal oxygen uptake MONARK839E cycle ergometer test, all the other use BiospaceInbody720 to detect.If there is following situation, this experiment will be excluded from.1, smoker 2, have chronic disease history 3, take nutritious supplementary pharmaceutical.What every volunteer was told that this experiment likely occurs is not symptom, and endorsed Informed Consent Form.Be familiar with two stages of testing to laboratory and the instrument of use is asked in experiment, inform that they do not carry out any strenuous exercise in 72 hours and the meals situation of 3 days before have collected before testing.All experiments all complete at MONARK839E cycle ergometer.
Stage one:
The Astrand pattern of the MONARK839E cycle ergometer of the assessment use of maximal oxygen uptake.The detection of heart rate uses heart rate telemetering system, and pectoral girdle is tied up in front, is close to the position that V5 leads.Volunteer is required first to carry out to carry out under the intensity of 80W two minutes warm-up, and has a rest 5 minutes, the Abstrand then carrying out the duration sub-peak load of 6 minutes tests, to reach a stable heart rate level.According to the value of the maximal oxygen uptake recorded, crowd is divided into 3 large group: GOOD group (VO2max>52ml.min-1.kg-1) AVERAGE groups (43ml.min-1.kg-1<VO2max<52ml.mi n-1.kg-1); POOR group (VO2max<43ml.min-1.kg-1).Each group, volunteer is distributed into two subgroups by stochastic averagina again, EB1 and EB2 eats the energy composition of embodiment 1 and embodiment 2 respectively, one day 2 times, eats one week.
Stage two:
The assessment that power exhausts the time also completes at MONARK839E cycle ergometer.Volunteer warms up 3 minutes under 80W intensity, has a rest 5 minutes, and test formally starts.The load started most is at 80W, and then increase 20W per minute is until power exhausts.The rhythm and pace of moving things of stepping bicycle remains on 70rpm.When volunteer's rhythm and pace of moving things under speech is encouraged can not keep 70rpm, the EOT end of test.The power time of exhausting is recorded to last second.Heart rate monitoring with one same method.All experiments are in certain height above sea level, and temperature is at 18 to 20 degree, and humidity is in the room of 40% to 60%, and experimental day, volunteer is apprised of 7: 30 and arrives experiment place on an empty stomach, and calmness takes a load off one's feet 15 minutes.Blood sample is taked after terminating with test before warming up immediately, adopts respectively and refers to blood and venous blood.
Result of the test:
Crowd characteristic:
In each large group and subgroup, each group of crowd is at the age, and height, body-mass index, body fat percentage does not have obvious difference.
The essential characteristic of table 2 volunteer
Power exhausts the time
In order to assess the performance 3 groups of varying level volunteers of embodiment 1 and embodiment 2, firmly the time of exhausting is assessed for we.In POOR group and GOOD group, two subgroups do not have obvious difference (P>0.05).But in AVERAGE group, have obvious difference (p=0.012) between two subgroups, EB2 group successful is better than EB1 group.
Table 3 power exhausts the time (min)
Group EB1 EB2
Poor 7.87±1.53 7.23±1.18
Average 9.40±0.77 7.99±0.81
Good 9.77±1.27 9.61±0.67
Reached for 75% maximum heart rate time
Table 4 reached for 75% maximum heart rate time
Group EB2 EB1
Poor 254.2±89.70 285.8±68.53
Average 275±63.17 296.17±96.03
Good 346.67±29.7 364.00±16.10
Blood sample analysis
The value of blood lactase acid can be used for assessing endurance, and the value of blood lactase acid and maximal oxygen uptake height correlation, the value of blood lactase acid is subject to again the impact of meals at ordinary times, and high carbohydrate meals can cause increasing of blood lactase acid.The embodiment 1 and 2 of this experiment sees the following form for the impact of blood lactase acid.
The blood lactase acid value of front and back tested by table 5
In addition, owing to containing dibydro myricetrin in composition of the present invention, the effect be therefore used for by hydrogen myricetin improving rat motor ability in low-oxygen environment is tested:
Method: 120 male Sprague – Dawley rats are divided into normal oxygen control group at random, hypoxemia control group, rhodiola root group (200mg/kg) and low group (50mg/kg), in (75mg/kg), high dose (100mg/kg) group, often organize 20, each group is given after relative medicine intervenes 7 days respectively, except normal oxygen group, all the other 5 groups are all placed in the low-pressure oxygen cabin 24 hours being equivalent to 5000m height above sea level, all rats all adopt rotary-type running machine power to exhaust experiment, observe medicine exhausts time impact on running power, further observation metabolism of rat index, the change of skeletal muscle mitochondrial respiratory enzyme activity, as Figure 1-5.
Result: compared with hypoxemia control group, of the present invention group of high, middle dosage group can significant prolongation rat running power exhaust the time (P<0.05) in hypobaric hypoxia environment, in dose dependent, lactic acid in serum can be reduced pile up and reduce LDH and BUN content simultaneously, skeletal muscle mitochondrial respiratory chain complex enzyme (I, IV, V) active obviously enhancing (P<0.05).
Conclusion is under hypobaric hypoxia environment, and the effective ingredient in the present invention is by regulating the exercise tolerance of the biosynthesis enhancing body of skeletal muscle Mitochondria.
As shown in Figure 1: through one-way analysis of variance: the middle dosage group of JD-001 more all has obvious significant difference (P<0.05) with plateau control group and positive controls, namely in JD-001 the exercise tolerance of dosage intervention group rat rat under hypobaric hypoxia condition apparently higher than plateau control group and positive controls.
More than test explanation, other formulas of antifatigue energy composition of the present invention can reach good antifatigue effect equally.Above-mentioned test shows, the effect highly significant of antifatigue energy composition of the present invention in antifatigue, and also has anoxia tolerance function.
What finally illustrate is, above embodiment is only in order to illustrate technical scheme of the present invention and unrestricted, although with reference to preferred embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that, can modify to technical scheme of the present invention or equivalent replacement, and not departing from aim and the scope of technical solution of the present invention, it all should be encompassed in the middle of right of the present invention.

Claims (5)

1. an antifatigue energy composition, it is characterized in that: energy composition raw material comprises following component by weight: expanded black rice powder 150-400 part, oatmeal 150-400 part, coconut oil 20-100 part, corn syrup 100-300 part, soybean isolate protein powder 20-150 part, maltodextrin 100-300 part, carnitine 1-30 part, vine tea flavone extract 1-30 part, grape seed extract 1-30 part, Quercetin extract 1-30 part, n-octacosanol 0.001-0.1 part, caffeine 0.01-0.5 part, branched-chain amino acid 10-40 part, taurine 10-40 part, low fat cocoa powder 10-40 part, vanilla 0.1-0.8 part.
2. antifatigue energy composition according to claim 1, it is characterized in that: energy composition raw material comprises following component by weight: expanded black rice powder 200-300 part, oatmeal 200-300 part, coconut oil 40-80 part, corn syrup 120-250 part, soybean isolate protein powder 40-120 part, maltodextrin 150-200 part, carnitine 1-20 part, vine tea flavone extract 1-20 part, grape seed extract 1-20 part, Quercetin extract 1-20 part, n-octacosanol 0.001-0.003 part, caffeine 0.01-0.5 part, branched-chain amino acid 10-20 part, taurine 10-20 part, low fat cocoa powder 10-20 part, vanilla 0.1-0.6 part.
3. antifatigue energy composition according to claim 2, it is characterized in that: energy composition raw material comprises following component by weight: expanded black rice powder 200-260 part, oatmeal 200-260 part, coconut oil 40-80 part, corn syrup 120-200 part, soybean isolate protein powder 40-100 part, maltodextrin 150-180 part, carnitine 1-10 part, vine tea flavone extract 1-10 part, grape seed extract 1-10 part, Quercetin extract 1-10 part, n-octacosanol 0.001-0.003 part, caffeine 0.01-0.5 part, branched-chain amino acid 10-20 part, taurine 10-20 part, low fat cocoa powder 10-20 part, vanilla 0.1-0.6 part.
4. antifatigue energy composition according to claim 3, is characterized in that: energy composition raw material comprises following component by weight: 250 parts, expanded black rice powder, oatmeal 250 parts, coconut oil 60 parts, corn syrup 130 parts, soybean isolate protein powder 60 parts, maltodextrin 170 parts, carnitine 5 parts, vine tea flavone extract 5 parts, grape seed extract 5 parts, Quercetin extract 5 parts, n-octacosanol 0.003 part, caffeine 0.5 part, branched-chain amino acid 13 parts, taurine 16 parts, low fat cocoa powder 16 parts, vanilla 0.3 part.
5. the arbitrary described antifatigue energy composition of a claim 1-4 is preparing the application in anti-fatigue medicament, anti-fatigue health-product containing, antifatigue food.
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CN105285634B (en) * 2015-11-11 2017-12-01 浙江工商大学 A kind of training proposes acting type natural function potus composition and its application
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101589808A (en) * 2008-05-26 2009-12-02 萨哈春食品供应有限公司 The beverage preparation that contains curcumin extraction
CN101919801A (en) * 2009-07-14 2010-12-22 无锡健而乐医药科技有限公司 Solid effervescent mixture for oral absorption
CN102210670A (en) * 2011-04-08 2011-10-12 中国人民解放军总后勤部卫生部药品仪器检验所 Use of flavonol compound in preparation of antihypoxic medicines or foods
CN103005260A (en) * 2012-12-21 2013-04-03 北京康比特体育科技股份有限公司 Antioxidant nutritional composition and manufacturing method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006326459B2 (en) * 2005-12-13 2012-09-20 Archer-Daniels-Midland Company Proteinaceous food products and methods of producing these food products
RU2557174C2 (en) * 2012-05-07 2015-07-20 Премьер Ньютришн Корпорейшн Pureed compositions having specific carbohydrate ratios and their usage method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101589808A (en) * 2008-05-26 2009-12-02 萨哈春食品供应有限公司 The beverage preparation that contains curcumin extraction
CN101919801A (en) * 2009-07-14 2010-12-22 无锡健而乐医药科技有限公司 Solid effervescent mixture for oral absorption
CN102210670A (en) * 2011-04-08 2011-10-12 中国人民解放军总后勤部卫生部药品仪器检验所 Use of flavonol compound in preparation of antihypoxic medicines or foods
CN103005260A (en) * 2012-12-21 2013-04-03 北京康比特体育科技股份有限公司 Antioxidant nutritional composition and manufacturing method thereof

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