CN102266051B - Antifatigue composition and preparation method thereof - Google Patents
Antifatigue composition and preparation method thereof Download PDFInfo
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Abstract
The invention provides an antifatigue composition and a preparation method thereof. The antifatigue composition comprises the following active ingredients in part by weight: 50 to 300 parts of rhodiola rosea extract, 50 to 300 parts of siberian ginseng extract and 500 to 5,000 parts of L-carnitine or pharmaceutically acceptable salts thereof. A test proves that when L-carnitine is cooperatively used with rhodiola rosea and siberian ginseng, the fatigue of a human body can be released and the synergism is achieved.
Description
Technical field
The present invention relates to a kind of health food, be specifically related to a kind of composition of antifatigue, its preparation and preparation method thereof.
Background technology
Sports fatigue refers to that the physiology course of physical function can not continue can not keep predetermined exercise intensity at specified level and/or integral body.
The generation of sports fatigue is many-sided, as: metabolic waste is piled up, movable desired substance exhaustion etc.During high-intensity exercise, energy requirement is greater than the maximum aerobic metabolism power and the high-caliber anaerobic metabolism of needs of individuality.When maximum intensity moved to fatigue, phosphocreatine (CP) was by lot of consumption (reaching reserves 90%), and then concentration reduces in muscle; Can cause fatigue; The energize of the generation of ADP and ATP constantly consumes in the mitochondria, as ADP again phosphorylation generate ATP speed and slow down, also can cause fatigue.H
+Be the important reason of sports fatigue, when sports fatigue, muscle pH can reduce to 6.33, and this is to cause tired principal element: 1) suppress the phosphofructokinase activity and reduction sugar decomposition speed; 2) the competitive Ca that suppresses
2+Reduce the cross-bridges activity in conjunction with TnC; 3) suppress sarcoplasmic reticulum ATP-ase and reduce Ca
2+Heavily absorb and Ca subsequently
2+Discharge.
Rhodiola root (Rhodiola rosea), English name Roseroot is Crassulaceae renascent herb or shrub plant, is grown in the high and cold pollution-free area of height above sea level 800-2500 rice, belongs to rare wild plant.Because its growing environment is abominable, like anoxic, low temperature drying, blast, receive ultraviolet ray irradiation, day and night temperature big, so rhodiola root has very strong vitality and special adaptability.These article are area, Asia traditional medicinal material commonly used, have the system of exciting nerve, increase operating efficiency, eliminate effects such as fatigue and prevention high mountain disease.In the motion process; Human body usually is in the state of anoxic, and rhodiola root can significantly improve the ability of the anti-anoxic of human body, improves the energetic supersession of anoxic body skeletal muscle; Promote the body aerobic metabolism; Lactic acid content in blood, cardiac muscle and the brain is descended, improve the aerobic metabolism of vital tissues such as the heart, brain, lung, promote body the adaptation of anaerobic environment and the generation of delay fatigue.Research shows that also rhodiola root can reduce the level of serotonin in the brain, and serotonin causes the material of motility central nerve fatigue just; Rhodiola root can also cause myocardium catecholamine and CAMP to raise through preventing stress reaction, and plays the cardiovascular effect of protection.These are to promoting that sport people health, raising sports achievement, relieving sports fatigue all are very necessary and important.
Wilsonii is an Araliaceae; Flavor suffering, little hardship, slightly warm in nature; Have bowl spares, smart, the strong will of benefit, dispel the wind wet, strengthen the bone, functions such as blood circulation and promoting silt, the diuresis of being good for the stomach; Can reconcile immunity, to antifatigue, improve hypoxia-bearing capability, to anti-ageing, alleviate toxicity of anticancer agents, and have and promote the nerve conduction function to improve the effect of recovering.The strenuous exercise lower body is in a kind of stress situation, and wilsonii helps enhancing body to the adverse factor resistivity, comprises overexercise.Active ingredient-the eleutheroside that contains in the wilsonii can stimulate the mind & body vigor, improves that muscle this means the aerobic exercise that human body can maintain a more long to the use of oxygen in the motion process, and from sports fatigue, recovers quickly.
It is the antifatigue effect of the TPSH health products of main component that bibliographical information rhodiola root, wilsonii are arranged, see that He Li Qing etc. writes " the preliminary test research of TPSH health products antifatigue effect is published in " practical preventive medicine " the 6th phase in December, 2006.The document discloses rhodiola root and wilsonii and has united to use and have antifatigue effect.
The present invention is on the basis of existing product, provides a kind of antifatigue effect stronger composition.
Summary of the invention
The invention provides a kind of composition with anti-fatigue health-caring function.
The present invention also provides a kind of method for compositions for preparing antifatigue.
The composition of a kind of antifatigue provided by the invention contains following active component: gadol extract, siberian Ginseng P.E, l-cn or its pharmaceutically acceptable salt.
Concrete, said composition contains the active component of following weight portion: gadol extract 50-300 part, siberian Ginseng P.E 50-300 part, l-cn or its pharmaceutically acceptable salt 500-5000 part.
Preferably, said composition contains the active component of following weight portion: gadol extract 100-300 part, siberian Ginseng P.E 100-200 part, l-cn or its pharmaceutically acceptable salt 1000-2000 part.
In the above-mentioned composition:
Described weight portion can be the known unit of weights of field of medicaments such as μ g, mg, g, kg, or its multiple, like 100mg, 10g etc.;
Said gadol extract is the water extract of rhodiola root, contains to be no less than 3% rhodioside;
Said siberian Ginseng P.E is the water extract of wilsonii, contains to be no less than 0.8% eleutheroside B+E;
Said l-cn pharmaceutically acceptable salt is selected from one or more in L-carnitine-L-tartrate, l-cn fumarate or the L-carnitine hydrochloride.
The composition of antifatigue provided by the invention also contains pharmaceutically acceptable carrier or diluent and forms.
Said composition is solid pharmaceutical preparation or liquid preparation; Said solid pharmaceutical preparation is tablet, capsule, pulvis or soft capsule; Said liquid preparation is an oral liquid.
Said pharmaceutically acceptable carrier or diluent are selected from one or more in xylitol, D-sorbite, isomalt, isomaltoketose, sweet mellow wine, ethanol, microcrystalline cellulose, lactose, HPMC, soybean oil or the dolomol.
The present invention also provides a kind of method for compositions for preparing antifatigue, may further comprise the steps:
1) take by weighing l-cn or its pharmaceutically acceptable salt, gadol extract, siberian Ginseng P.E raw material, sieve, subsequent use;
2) with adding pharmaceutically acceptable carrier or diluent in the active component in the step 1), mix, be prepared into conventional formulation according to the equivalent method of progressively increasing.
Usage and dosage: every day, oral or Instant Drinks were 1-3 time, each 3-5 grain or sheet or bag, every, bag or sheet count 0.1-1.0g to contain l-cn, contain gadol extract 0.01-0.5g, contain siberian Ginseng P.E 0.01-0.5g.
A kind of composition that is used for antifatigue provided by the invention has the following advantages:
1, rhodiola root, wilsonii have the effect that improves human body oxidation resistance and hypoxia-bearing capability; In the big intensity endurance exercise process, the consumption of oxygen can be up to ten times of oxygen demand at ordinary times, and human body is in oxidative stress status; Levels of peroxide increases; Gadol extract and siberian Ginseng P.E can improve antioxidant capacity of human body and hypoxia-bearing capability, help to improve exercise tolerance, delay fatigue; L-cn can more effectively make the body fat oxidation Decomposition be converted into energy through quickening the burning of body fat, improves the endurance level of body, thereby improves sports achievement, is particularly suitable for the endurance exercise project;
2, the present invention compares with the preliminary test research (being published in " practical preventive medicine " the 6th phase in December, 2006) of TPSH health products antifatigue effect; On the basis of rhodiola root, wilsonii, added l-cn; L-cn carries out the oxidation energy supply owing to can promote aliphatic acid to pass mitochondrial membrane, therefore when motion, can promote the burning of fat in the health that energy is provided, and l-cn can also promote the oxidation utilization of branched-chain amino acid simultaneously; Can change the activity of mitochondria internal respiration enzyme; Thereby can improve the ability of body aerobic oxidation energy supply, so the sportsman suitably takes the energy that l-cn can improve in the motion and generate, improve the endurance level of body; Thereby the raising sports achievement is particularly suitable for the endurance exercise project;
3, confirm through overtesting: l-cn and rhodiola root, wilsonii share and can improve human tolerance, and it is tired to alleviate the motion back, has synergistic function.
The specific embodiment
Following examples are used to explain the present invention, but are not used for limiting scope of the present invention.
For the buying producer of gadol extract and siberian Ginseng P.E and l-cn is in order to further specify realizability of the present invention, but should not be used for limiting scope of the present invention.
The l-cn of raw material of the present invention or its pharmaceutically acceptable salt are available from Shenyang Keshuo Nutrition Technology Co., Ltd.; Gadol extract is available from Jiahe, Shaanxi bio tech ltd; Siberian Ginseng P.E is available from Jiahe, Shaanxi bio tech ltd.
Embodiment 1: capsule:
1, prescription (weight): L-carnitine-L-tartrate 1200g, gadol extract 300g, siberian Ginseng P.E 150g, microcrystalline cellulose 100g, dolomol 10g.
2, preparation method:
1) take by weighing L-carnitine-L-tartrate, gadol extract, siberian Ginseng P.E according to prescription, cross 40 mesh sieves respectively, subsequent use;
2) take by weighing microcrystalline cellulose and dolomol according to prescription, above-mentioned supplementary material is mixed by the equivalent method of progressively increasing, pour capsule into and fill in the mould, can capsule, polishing, packing.
3, specification: contain L-carnitine-L-tartrate 0.4g, gadol extract 0.1g, siberian Ginseng P.E 0.05g in every capsules.
Embodiment 2: pulvis
1, prescription (weight): l-cn fumarate 5000g, gadol extract 50g, siberian Ginseng P.E 300g, isomalt 5000g.
2, preparation method:
1) take by weighing l-cn, gadol extract, siberian Ginseng P.E according to prescription, cross 40 mesh sieves respectively, subsequent use;
2) take by weighing isomalt according to prescription, above-mentioned supplementary material is mixed packing by the equivalent method of progressively increasing.
3, specification: every bag contains l-cn fumarate 1g, gadol extract 0.01g, siberian Ginseng P.E 0.06g.
Embodiment 3: tablet
1, prescription (weight): l-cn 2000g, gadol extract 300g, siberian Ginseng P.E 100g, isomalt 1000g, lactose 1500g, dolomol 40g.
2, preparation method
1) take by weighing l-cn, gadol extract, siberian Ginseng P.E according to prescription, cross 40 mesh sieves respectively, subsequent use;
2) take by weighing isomalt, lactose according to prescription, above-mentioned supplementary material is mixed by the equivalent method of progressively increasing, use 50% ethanol, the system softwood as adhesive; Above-mentioned softwood is processed particle through waving of 14 eye mesh screens in the granulator, particle is inserted in the multi-functional boiling drier, about 40 minutes of 50 ℃ of fluidized dryings; The control pellet moisture is 5%, and whole grain adds dolomol then in particle; Total mixed, compressing tablet, packing;
3, specification: every contains l-cn 0.4g, contains gadol extract 0.06g, contains siberian Ginseng P.E 0.02g.
Embodiment 4: tablet
1, prescription (weight): l-cn 2000g, gadol extract 200g, siberian Ginseng P.E 50g, isomalt 1000g, lactose 1500g, dolomol 40g.
2, preparation method
1) take by weighing l-cn, gadol extract, siberian Ginseng P.E according to prescription, cross 40 mesh sieves respectively, subsequent use;
2) take by weighing isomalt, lactose according to prescription, above-mentioned supplementary material is mixed by the equivalent method of progressively increasing, use 50% ethanol, the system softwood as adhesive; Above-mentioned softwood is processed particle through waving of 14 eye mesh screens in the granulator, particle is inserted in the multi-functional boiling drier, about 40 minutes of 50 ℃ of fluidized dryings; The control pellet moisture is 5%, and whole grain adds dolomol then in particle; Total mixed, compressing tablet, packing;
3, specification: every contains l-cn 0.4g, contains gadol extract 0.04g, contains siberian Ginseng P.E 0.01g.
Embodiment 4: human experimentation
1 experimental subjects and method
1.1 experimental subjects
Is research object with 52 man's long-distance runnings of certain sport university to sportsman's (21.8 ± 0.75 years old mean age).
1.2 experiment is divided into groups
Divide into groups: 65 experimenters are divided into 5 groups at random, and blank control group (N=13) is taken placebo, 4/day; Control group 1 is taken the composition that contains l-cn 2.4g, and control group 2 is taken and contained gadol extract 0.48g, contains the composition of siberian Ginseng P.E 0.24g; Experimental group 1 is taken anti-Fatigue Composition tablet group of the present invention, and (embodiment 3; Every contains l-cn 0.4g, contains gadol extract 0.06g, contains siberian Ginseng P.E 0.02g) 4 slices/day; Experimental group 2 is taken anti-Fatigue Composition capsule group of the present invention, and (embodiment 1; Every contains L-carnitine-L-tartrate 0.4g, contains gadol extract 0.1g, contains siberian Ginseng P.E 0.05g.) 3/day, all took continuously for 8 weeks.Whole experimental session, and prohibit clothes other antifatigue food and medicines.
1.3 experimental technique
Venous blood when requiring the experimenter before test, to come the laboratory on an empty stomach to get peace and quiet; Carry out exercise load (on the Monark power meter, moving) before the motion, first limber up 1min (0 load) begins with 50W power then; Increasing load progressively; Reach 70%Hrmax (drawing) about 3 minutes, after this promptly no longer increase load, continue 60 minutes to pedal by trial test mensuration.Centre of motion rate adopts the monitoring of Polar table.Control breadboard temperature and humidity.The experimenter tests after taking 8 all nutriment once more.
1.4 index and method
Test index: get ear blood 1 per half an hour in the motion, surveys lactic acid.Immediate postexercise, motion back were measured the recovery heart rate on the the 3rd, 9,15 minute, are got ear blood survey lactic acid.Second day early morning, extracting vein blood was measured serum superoxide dismutases (SOD) vigor.
Method of testing: blood lactic acid adopts YSI 1500 SPORT LACTATEANALYZER to measure, and method is the enzyme electrode method; Serum superoxide dismutases (SOD) vigor adopts xanthine oxidase to measure, and determining instrument is 721 type spectrophotometers.
1.5 result's statistics
Data adopts SPSS10.0 software, and all data are represented with means standard deviation, adopt the variance and the pairing T method of inspection.
2 experimental results
2.1 the comparison of blood lactic acid concn
Table 1: blood lactic acid concn
| Divide into groups | Quiet | Immediate postexercise | Motion finishes back 3min | Motion finishes back 9min | Motion finishes back 15min |
| Blank control group | 1.63±0.46 | 3.22±0.42 | 3.23±0.53 | 2.21±0.52 | 1.61±0.43 |
| Control group 1 | 1.58±0.43 | 3.17±0.43 | 3.03±0.58 | 2.0±0.50 | 1.56±0.53 |
| Control group 2 | 1.60±0.51 | 3.08±0.40 | 2.87±0.54 | 1.68±0.48 | 1.58±0.49 |
| Experimental group 1 | 1.54±0.32 | 2.45±0.46 | 1.53±0.59 **※※★ | 1.35±0.45 ※※★ | 1.32±0.58 |
| Experimental group 2 | 1.58±0.34 | 2.50±0.42 | 1.58±0.56 **※※★ | 1.34±0.44 ※※★ | 1.35±0.53 |
Compare with blank control group,
*P＜0.01; Compare with control group 1,
※ ※P＜0.01; Compare with control group 2,
★P＜0.05.
The result finds out from table 1:
Immediate postexercise, the blood lactic acid concn of control group 1, control group 2 and experimental group slightly reduces, but does not produce significant difference;
Motion finishes back 3min, compares with blank control group, control group 1, control group 2 respectively, and the blood lactic acid concn of experimental group 1, experimental group 2 has reduction (P＜0.01, P＜0.05) in various degree;
Motion finishes back 9min, the level when the blood lactic acid concn of control group 2 returns to peace and quiet;
Motion finishes back 15min, the level when control group 1 just returns to peace and quiet with blank control group.
Lactic acid is the product that energy substance catabolism obtains in the body in the motion process, a large amount of acidic materials accumulation, cause muscle, joint acid expand and spirit tired.Take the experimental group sample, help to accelerate the removing speed of blood lactic acid in the body, help prolonging exercise tolerance, improve locomitivity.
2.2 motion finishes to recover in back 3 minutes the comparison of heart rate
The heart rate of immediate postexercise and motion back 3min test subject, the result sees table 2.
Table 2: the heart rate that the motion end recovered in back 3 minutes (inferior/minute)
Compare with blank control group,
*P＜0.01; Compare with control group 1,
※P＜0.05; Compare with control group 2,
★P＜0.05.
Can find out by table 2:
Motion finishes back 3 minutes, and the recovery of experimental group 1 and experimental group 2 heart rate is (P＜0.01) significantly, and control group 1 recovers obviously (P＜0.05) with control group 2 heart rate; Compare obvious (P＜0.05) that the heart rate of experimental group 1 and experimental group 2 recovers respectively with 2 with control group 1.
The heart rate resume speed is fast, shows that experimental group experimenter exercise tolerance is good, and locomitivity is strong.Therefore can find out that experimental group experimenter's antifatigue effect is better than control group.
2.3 oxidation resistance test result
Experiment back m seq is serum superoxide dismutases (SOD) vigor of experiments of measuring group 1, experimental group 2, blank control group, control group 1 and control group 2 respectively, and experimental result is seen table 3.
Table 3: the experiment back is to the influence of 4 groups of experimenter's oxidation resistances
Compare with control group 1,
※P＜0.05; Compare with control group 2,
★P＜0.05.
Can know that by table 4 the SOD vigor in five groups of experimenter mornings next day is all high than morning on the previous day, but experimental group 1 is significantly higher than the previous day (P＜0.05) with experimental group 2, and control group 1 and control group 2 no significant differences.Compare with 2 with control group 1 respectively, experimental group 1 has notable difference (P＜0.05) with experimental group 2.
Show that this patent obtains composition and can promote body SOD to raise effectively, has strengthened the ability of body Green Tea Extract.
Discuss: motion causes that the body free radical increases, and too much free radical can cause some important metabolic enzymes because of the cross-linked polymeric inactivation, causes a series of pathological change, causes the ability to work of human body to descend and the generation sense of fatigue.Therefore, accelerate the removing speed of free radical, improve the anti-oxidative defense function, help to improve locomitivity, promote fatigue recovery, reduce the damage of peroxidation body.
3, conclusion
From whole experiment; The composition of antifatigue provided by the invention has the effect of Synergistic, and experimenter's blood lactic acid resume speed is accelerated, and it is also fast that heart rate recovers; This all is the key factor that helps prolonging exercise tolerance, helps the raising of locomitivity.Motion can cause that the body free radical increases, and too much free radical can cause some important metabolic enzymes because of the cross-linked polymeric inactivation, causes a series of pathological change, causes the ability to work of human body to descend and generation fatigue.Therefore, accelerate the removing speed of free radical, improve the anti-oxidative defense function, significant to improving locomitivity.The anti-oxidant result of this experiment shows, takes this beverage and can promote body SOD to raise effectively, can improve the ability of body Green Tea Extract effectively, to improving locomitivity and promoting that fatigue recovery also has certain effect.
Though, used general explanation, the specific embodiment and test in the preceding text, the present invention has been done detailed description, on basis of the present invention, can to some modifications of do or improvement, this will be apparent to those skilled in the art.Therefore, these modifications or the improvement on the basis of not departing from spirit of the present invention, made all belong to the scope that requirement of the present invention is protected.
Claims (7)
1. the composition of an antifatigue; It is characterized in that the active component of said composition is made up of the active component of following weight portion: gadol extract 50-300 part, siberian Ginseng P.E 50-300 part, l-cn or its pharmaceutically acceptable salt 500-5000 part; Said l-cn pharmaceutically acceptable salt is selected from one or more in L-carnitine-L-tartrate, l-cn fumarate or the L-carnitine hydrochloride; Said gadol extract is the water extract of rhodiola root, contains to be no less than 3% rhodioside; Said siberian Ginseng P.E is the water extract of wilsonii, contains to be no less than 0.8% eleutheroside B+E.
2. composition according to claim 1; It is characterized in that the active component of said composition is made up of the active component of following weight portion: gadol extract 100-300 part, siberian Ginseng P.E 100-200 part, l-cn or its pharmaceutically acceptable salt 1000-2000 part.
3. composition according to claim 1 and 2 is characterized in that, the auxiliary material of said composition is pharmaceutically acceptable carrier or diluent.
4. composition according to claim 3 is characterized in that, said composition is solid pharmaceutical preparation or liquid preparation.
5. composition according to claim 4 is characterized in that said solid pharmaceutical preparation is selected from tablet, capsule or pulvis; Said liquid preparation is an oral liquid.
6. composition according to claim 3; It is characterized in that said pharmaceutically acceptable carrier or diluent are selected from one or more in xylitol, D-sorbite, isomalt, isomaltoketose, sweet mellow wine, ethanol, microcrystalline cellulose, lactose, HPMC, soybean oil or the dolomol.
7. one kind prepares the said method for compositions of claim 3, it is characterized in that this method may further comprise the steps:
1) take by weighing l-cn or its pharmaceutically acceptable salt, gadol extract, siberian Ginseng P.E raw material, sieve, subsequent use;
2) with adding pharmaceutically acceptable carrier or diluent in the active component in the step 1), mix, be prepared into conventional formulation according to the equivalent method of progressively increasing.
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| CN105454967A (en) * | 2015-12-11 | 2016-04-06 | 北京康比特体育科技股份有限公司 | Composition capable of relieving sports fatigue or improving sports ability and sports beverage thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1476841A (en) * | 2003-07-15 | 2004-02-25 | 上海博泰医药科技有限公司 | Puerarin dispersing tablet composition and its preparation method |
| CN1546017A (en) * | 2003-11-30 | 2004-11-17 | 杨喜鸿 | Compostion preparation of orlistat |
| CN101248873A (en) * | 2008-04-03 | 2008-08-27 | 四川健丰科技发展有限公司 | Drinking food product with sight protection function |
-
2011
- 2011-06-14 CN CN2011101587457A patent/CN102266051B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1476841A (en) * | 2003-07-15 | 2004-02-25 | 上海博泰医药科技有限公司 | Puerarin dispersing tablet composition and its preparation method |
| CN1546017A (en) * | 2003-11-30 | 2004-11-17 | 杨喜鸿 | Compostion preparation of orlistat |
| CN101248873A (en) * | 2008-04-03 | 2008-08-27 | 四川健丰科技发展有限公司 | Drinking food product with sight protection function |
Non-Patent Citations (1)
| Title |
|---|
| 许贵军等.刺五加化学成分研究进展.《中医药信息》.2007,第24卷(第6期),20-21. * |
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