CN107802507B

CN107802507B - Application of thorn-reducing composition in preparation of oral care product and oral care product

Info

Publication number: CN107802507B
Application number: CN201711120839.9A
Authority: CN
Inventors: 葛华亭; 邹振海; 曾育聪; 黄慕芸; 张太军; 陈岱宜
Original assignee: Mingchen Health Co ltd
Current assignee: Guangdong Mingchen Daily Chemical Co ltd
Priority date: 2017-11-14
Filing date: 2017-11-14
Publication date: 2020-07-28
Anticipated expiration: 2037-11-14
Also published as: CN107802507A

Abstract

The invention discloses an application of a thorn-reducing composition in an oral care product and the oral care product. The thorn-reducing composition comprises the following components in percentage by weight: 0.5-10% of trimethylglycine, 0.0005-0.05% of perillaseed and 0.01-1.0% of dipotassium glycyrrhizinate. The composition has reduced irritation of oral care products, improved mildness and comfort of mouthfeel, and reduced xerostomia after use.

Description

Application of thorn-reducing composition in preparation of oral care product and oral care product

Technical Field

The invention relates to an anti-acne composition, in particular to an anti-acne composition applied to an oral care product, which has the advantages of reducing the irritation of the oral care product, enhancing the mildness and the comfort of the mouthfeel and relieving the phenomenon of xerostomia after use, and belongs to the technical field of oral care.

Background

Toothpaste, mouthwash, tooth powder and the like are daily oral cleaning and nursing products for people, and the mouthfeel of the products is an important mark for consumers to evaluate the quality and decide whether to purchase the products. An oral cleaning and nursing product is important for consumers to buy repeatedly, and the comfortable, mild and pleasant mouthfeel plays a role.

The raw materials in the oral cavity cleaning and nursing product are various, some bad smells such as bitter taste, astringent taste, miscellaneous gas can be brought, these bad smells can stimulate oral mucosa, finally influence the taste of product, surfactant in the product can stimulate oral mucosa when giving cleaning function, influence the taste of product, the flavor is covering the bad smell of product, also can stimulate oral mucosa when increasing cool taste, most natural spices in the oral cavity nursing product also have bad bitter taste simultaneously, influence the taste of product more.

The oral care product sold in the market at present has larger irritation to oral mucosa, the oral cavity generally feels dry after use, and aiming at the problem of the existing product, the invention aims to provide the irritation reducing composition to reduce the irritation of the product, so that the mouth feel is milder, moist, fresh and pleasant, and the market competitiveness of the product is improved.

Disclosure of Invention

In order to overcome the defects of the prior art, the invention aims to provide the application of the thorn-reducing composition in the oral care product, the three components of trimethylglycine, perillaseed and dipotassium glycyrrhizinate are added into the oral care product, and the product is mild, moist, fresh and pleasant through the synergistic effect of the three components, so that the dryness of the oral cavity after use is reduced, and the overall taste of the product is improved.

Another object of the present invention is to provide an oral care product containing the composition, which is mainly one of toothpaste, mouthwash, tooth powder, etc.

The purpose of the invention is realized by the following technical scheme:

a thorn-reducing composition is applied to an oral care product and comprises three components of trimethylglycine, perillaseed and dipotassium glycyrrhizinate; wherein the addition amount of the trimethylglycine is 0.5-10%, the addition amount of the perillaseed is 0.0005-0.05%, and the addition amount of the dipotassium glycyrrhizinate is 0.01-1.0%; the total amount of the thorn-reducing composition in the oral care product is controlled within 11.0%.

The thorn reducing composition is characterized in that the preferable adding amount of trimethylglycine is 1.0-5.0%, the preferable adding amount of perillaseed is 0.002-0.02%, the preferable adding amount of dipotassium glycyrrhizinate is 0.05-0.5%, and the total adding amount of the thorn reducing composition in an oral care product is within 5.5%.

The oral care product is one of toothpaste, mouthwash, tooth powder and the like.

A toothpaste containing the thorn-reducing composition comprises the following raw material components in percentage by weight:

0.5-10% of trimethylglycine, 0.0005-0.05% of perillaseed, 0.01-1.0% of dipotassium glycyrrhizinate, 20-50% of abrasive, 20-55% of humectant, 1.0-1.5% of thickener, 1.8-3% of surfactant, 0.05-0.2% of sweetening agent, 0.1-0.3% of preservative, 1.0-1.5% of essence and deionized water are added to 100%.

The abrasive is one or a mixture of two of calcium carbonate, calcium hydrophosphate, silicon dioxide and aluminum hydroxide.

The humectant is one or more of sorbitol, glycerol, polyethylene glycol and propylene glycol.

The thickener is one or more of sodium carboxymethylcellulose, xanthan gum, guar gum and carrageenan.

The surfactant is one or more of sodium lauryl sulfate, sodium lauroyl sarcosinate and cocamidopropyl betaine.

The sweetener is one or two of saccharin sodium and acesulfame potassium.

The preservative is one or a mixture of sodium benzoate and nipagin ester.

A mouth wash containing an anti-irritant composition comprises the following raw material components in percentage by weight:

0.5-10% of trimethylglycine, 0.0005-0.05% of perillaseed, 0.01-1.0% of dipotassium glycyrrhizinate, 10-30% of humectant, 0.5-2% of surfactant, 0.01-0.2% of sweetening agent, 0.1-0.3% of preservative, 0.2-0.5% of essence and deionized water are added to 100%.

The humectant is one or more of sorbitol, glycerol and propylene glycol.

The surfactant is one or more of tween, poloxamer and PEG-40 hydrogenated castor oil.

The sweetener is one or two of saccharin sodium, sucralose and thaumatin.

The preservative is one or a mixture of sodium benzoate and nipagin ester.

The collutory may also contain ethanol, xylitol, etc.

A dentifrice containing a dental spur reducing composition comprises the following raw material components in percentage by weight:

0.5-10% of trimethylglycine, 0.0005-0.05% of perillaseed, 0.01-1.0% of dipotassium glycyrrhizinate, 80-85% of abrasive, 3-5% of surfactant, 0.2-0.5% of sweetening agent, 0.1-0.3% of preservative, 1.5-2.5% of essence and deionized water are added to 100%.

The sweetener is one or two of saccharin sodium and acesulfame potassium.

The preservative is one or a mixture of sodium benzoate and nipagin ester.

The addition of the inventive spur-reducing composition to an oral care product has the following advantages and benefits:

1. the irritation of the oral care product can be obviously reduced, the taste of the product is improved, and the dryness of the oral cavity after use is reduced through the synergistic effect of the three components, so that the good effect of improving the overall quality of the product is achieved.

The irritation of the oral care product to the oral mucosa mainly comes from two aspects, on one hand, the irritation of the surfactant to the oral mucosa is realized, and the surfactant has permeability and can increase the permeability of the oral mucosa, so that the sensitivity to external irritation is increased; on the other hand, the stimulation of the essence to the oral mucosa is larger, particularly the stimulation of bad miscellaneous gas and bitter taste in the essence to the oral mucosa is larger, the permeability of the oral mucosa is increased by adding the surfactant, and the stimulation of the essence to the oral mucosa is further increased.

The trimethylglycine can reduce the irritation of the surfactant, keep the oral mucosa moist and reduce the irritation of the used surfactant to the oral mucosa and the dry oral cavity phenomenon caused by the irritation; the perillaseed as the high-power sweetener can reduce the bitter, astringent and other undesirable tastes in the essence, obviously reduce the irritation of the essence to oral mucosa, and ensure that the fragrance is purer and softer;

the dipotassium glycyrrhizinate has anti-inflammatory and anti-allergic effects, can reduce the sensitivity of oral mucosa to external stimulation, enhance the stress capability of the oral mucosa, repair damaged oral mucosa and synchronously repair the oral mucosa damaged by the stimulation of a product; the dipotassium glycyrrhizinate can reduce the overall irritation of the product, blend the taste of the product and enable the taste to be more fresh and harmonious.

The thorn-reducing composition can provide special sweet feeling which is incomparable with the traditional sweetening agent, so that the sweet feeling of the product can be improved, the mouthfeel is more lingering and mellow, and the unpleasant bitter taste of other components in the oral care product can be well covered, so that the overall mouthfeel of the product is improved.

Surprisingly, the oral care product containing the thorn-reducing composition is found to have good effects of increasing salivary secretion, keeping the oral cavity moist and reducing the oral cavity dryness after use through trial investigation.

2. The thorn-reducing composition disclosed by the invention is added into toothpaste, so that the mouthfeel of the toothpaste can be obviously improved, and a fresh and clean brand-new feeling is given to the oral cavity. The trimethylglycine can enable the foam of the surfactant to be finer and softer, and the mouth feel to be fresh and moist. The composition is added into the mouthwash, the overall taste is essentially different from other similar products, the taste is closer to the flavor of a beverage, the mouth feeling is particularly mild and fresh, the mouth cavity is moist and soft after gargling, the glycol is durable, and particularly for the mouthwash containing ethanol, the composition can obviously reduce the sharp stimulation of the ethanol to the oral mucosa, so that the product is mild, has moderate stimulation, and is also a different feeling for people pursuing the stimulation.

The composition is added into the dentifrice, can make up the defects of the dentifrice, has the advantages of strong friction force, good stain removal and whitening effects, is particularly suitable for people drinking tea and smoking, has the defects of high content of abrasive, heavy dust taste, large irritation to oral mucosa and easy drying of oral cavity after use, can well solve the defects of the dentifrice, and makes the dentifrice become a new favorite of oral care products.

3. According to the invention, trimethylglycine, perillaseed and dipotassium glycyrrhizinate are applied to the oral care product as the thorn reducing composition for the first time, and the thorn reducing composition has multiple effects of reducing product irritation, improving product mouthfeel and reducing oral dryness after use, so that the overall mouthfeel of the oral care product is improved, and the pursuit of consumers for low-irritation products is met.

Detailed Description

The invention discloses a thorn-reducing composition, which consists of three components of trimethylglycine, perillaseed and dipotassium glycyrrhizinate; wherein the addition amount of the trimethylglycine is 0.5-10%, the addition amount of the perillaseed is 0.0005-0.05%, and the addition amount of the dipotassium glycyrrhizinate is 0.01-1.0%; the anti-acne composition is applied to oral care products such as toothpaste, mouthwash, tooth powder and the like, and the total addition amount of the anti-acne composition in the oral care products is controlled within 11.0%.

The thorn-reducing composition is applied to an oral care product, wherein the preferable adding amount of trimethylglycine is 1.0-5.0%, the preferable adding amount of perillartine is 0.002-0.02%, the preferable adding amount of dipotassium glycyrrhizinate is 0.05-0.5%, and the total adding amount of the thorn-reducing composition in the oral care product is controlled within 5.5%.

The following is a brief description of the monomer feed to which the compositions of the invention relate:

trimethylglycine, also known as betaine, is purified from the honey of beetroot, has slight cool and sweet taste, is widely applied to the fields of cosmetics, foods, health products and the like, and can reduce the chemical irritation of products, particularly the irritation of surfactants, in the cosmetics. The betaine is a cell-regulated penetrant, has the functions of keeping the oral mucosa moist, improving the moisture retention of the oral cavity and relieving xerostomia caused by the reduction of salivary secretion, can obviously improve the mouth feel of the product when being used in an oral care product, and endows the oral cavity with fresh, clean, moist and pleasant fresh feeling.

The perilla pepperweed is called as perilla essence, is white crystal at normal temperature, has slight fragrance of the perilla, is a novel food additive with high sweetness (the sweetness is 2000 times of sucrose), low calorie and no toxicity, and can remove unpleasant odors such as bitterness and acerbity, so that the taste is softer, and the aftertaste is purer and more comfortable.

The dipotassium glycyrrhizinate is white or white-like powder, has special sweet taste, the sweetness is about 150 times of that of cane sugar, the mouthfeel is pure, the sweetening time is long, and the dipotassium glycyrrhizinate has multiple effects of detoxifying, inhibiting bacteria, diminishing inflammation, resisting allergy and the like and is widely applied to industries such as medicines, foods, cosmetics and the like.

The invention is further illustrated by the following specific examples, which are intended to be purely exemplary of a more detailed description and are not intended to limit the invention in any way.

Example 1

A toothpaste containing the thorn-reducing composition comprises the following components in percentage by weight:

1% of trimethylglycine, 0.02% of perillartine, 0.05% of dipotassium glycyrrhizinate, 45% of calcium carbonate, 5% of silicon dioxide, 2% of polyethylene glycol, 18% of sorbitol, 1.0% of sodium carboxymethylcellulose, 0.5% of guar gum, 2.5% of sodium lauryl sulfate, 0.5% of cocamidopropyl betaine, 0.2% of sodium pyrophosphate, 0.2% of sodium saccharin, 0.2% of nipagin esters, 1.5% of essence and deionized water added to 100%.

The manufacturing process comprises the following steps:

1) weighing perillartine, nipagin esters and essence, adding into a container A, and stirring for dissolving;

2) adding deionized water into the premixing pot B, adding trimethylglycine, dipotassium glycyrrhizinate, saccharin sodium, cocamidopropyl betaine and sodium pyrophosphate, and stirring to dissolve;

3) adding calcium carbonate, silicon dioxide, sodium carboxymethylcellulose, guar gum and sodium lauryl sulfate into a powder mixer;

4) sucking the liquid materials in the polyethylene glycol, the sorbitol and the premixing pot B into a paste making machine in a vacuum state, starting a scraper and stirring, sucking the powder materials into a powder mixer, opening the homogenizing after the powder materials are completely sucked, and performing homogenizing and degassing for 30 minutes;

5) vacuum degassing for 30 min, sucking the raw materials in the container A, homogenizing and degassing for 10 min, and obtaining the paste after the inspection is qualified.

Example 2

5% of trimethylglycine, 0.002% of perillartine, 0.5% of dipotassium glycyrrhizinate, 30% of calcium hydrophosphate, 10% of aluminum hydroxide, 3% of silicon dioxide, 5% of propylene glycol, 10% of glycerol, 10% of sorbitol, 0.5% of sodium carboxymethylcellulose, 0.5% of xanthan gum, 2.2% of sodium lauryl sulfate, 0.5% of sodium lauroyl sarcosinate, 0.2% of sodium pyrophosphate, 0.2% of acesulfame, 0.1% of parabens, 1.0% of essence and 100% of deionized water.

The manufacturing process comprises the following steps:

2) adding deionized water into the premixing pot B, adding trimethyl glycine, dipotassium glycyrrhizinate, acesulfame potassium, sodium lauroyl sarcosinate and sodium pyrophosphate, and stirring for dissolving;

3) adding calcium hydrogen phosphate, aluminum hydroxide, silicon dioxide, sodium carboxymethylcellulose, xanthan gum and sodium lauryl sulfate into a powder mixer;

4) sucking the liquid materials in the propylene glycol, the glycerol, the sorbitol and the premixing pot B into a paste making machine in a vacuum state, starting a scraper and stirring, sucking the powder materials into a powder mixer, opening homogenization after the powder materials are completely sucked, and performing homogenization and degassing for 30 minutes;

Example 3

3% of trimethylglycine, 0.05% of perillartine, 0.3% of dipotassium glycyrrhizinate, 20% of silicon dioxide, 3% of polyethylene glycol, 52% of sorbitol, 0.8% of sodium carboxymethylcellulose, 0.2% of carrageenan, 1.8% of sodium lauryl sulfate, 0.2% of sodium pyrophosphate, 0.05% of saccharin sodium, 0.3% of sodium benzoate, 1.0% of essence, 0.2% of titanium dioxide and deionized water added to 100%.

The manufacturing process comprises the following steps:

1) weighing perillaseed and essence, adding into the container A, and stirring for dissolving;

2) adding deionized water into the premixing pot B, adding trimethylglycine, dipotassium glycyrrhizinate, saccharin sodium and sodium pyrophosphate, and stirring for dissolving;

3) adding silicon dioxide, sodium carboxymethylcellulose, carrageenan, sodium lauryl sulfate and titanium dioxide into a powder mixer;

Example 4

A mouthwash containing a thorn reducing composition comprises the following components in percentage by weight:

10% of trimethylglycine, 0.0005% of perilla pepperweed, 0.01% of dipotassium glycyrrhizinate, 10% of glycerol, 10% of ethanol, 0.5% of tween, 0.01% of tamarind, 0.1% of parabens, 0.5% of essence, and the balance of deionized water, a pigment and a pH regulator.

The manufacturing process comprises the following steps:

adding trimethylglycine, dipotassium glycyrrhizinate, sweeten and pigment into deionized water, and stirring to dissolve to form a water phase; adding perillaseed, nipagin esters and essence into ethanol, stirring for dissolving, adding glycerol and tween, stirring to obtain transparent system, adding water phase, stirring to obtain transparent liquid, and regulating pH to a specified range; and finally standing, filtering and filling.

Example 5

0.5% of trimethylglycine, 0.05% of perillartine, 0.8% of dipotassium glycyrrhizinate, 10% of propylene glycol, 20% of sorbitol, 5% of xylitol, 1% of poloxamer, 1% of PEG-40 hydrogenated castor oil, 0.2% of saccharin sodium, 0.3% of sodium benzoate, 0.2% of essence, and the balance of deionized water, pigment and a pH regulator.

The manufacturing process comprises the following steps:

adding trimethylglycine, dipotassium glycyrrhizinate, saccharin sodium, sodium benzoate, xylitol and pigment into deionized water, and stirring to dissolve to form a water phase; adding perillaseed and essence into propylene glycol, stirring for dissolving, adding sorbitol, PEG-40 hydrogenated castor oil and poloxamer, stirring to obtain transparent system, adding water phase, stirring to obtain transparent liquid, and regulating pH to a specified range; and finally standing, filtering and filling.

Example 6

A dentifrice containing a composition for reducing dental caries comprises the following components by weight percent: 5% of trimethylglycine, 0.02% of perillartine, 1.0% of dipotassium glycyrrhizinate, 70% of calcium carbonate, 10% of silicon dioxide, 3% of sodium lauryl sulfate, 0.2% of saccharin sodium, 0.1% of parabens, 1.5% of essence and 100% of deionized water.

The manufacturing process comprises the following steps:

dissolving trimethylglycine, dipotassium glycyrrhizinate and saccharin sodium in water phase; uniformly mixing calcium carbonate, silicon dioxide and sodium lauryl sulfate, spraying the water phase into the powder while stirring, finally spraying the essence dissolving perillaseed and nipagin ester into the powder while stirring, conveying the powder to a grinding machine for grinding uniformly until no particles are observed visually, sieving by a 150-mesh sieve, and packaging.

Example 7

A dentifrice containing a composition for reducing dental caries comprises the following components by weight percent:

3% of trimethylglycine, 0.05% of perillartine, 0.5% of dipotassium glycyrrhizinate, 70% of calcium hydrophosphate, 15% of aluminum hydroxide, 4% of sodium lauryl sulfate, 1% of sodium lauroyl sarcosinate, 0.5% of acesulfame, 0.3% of sodium benzoate, 2.5% of essence and deionized water added to 100%.

The manufacturing process comprises the following steps:

dissolving trimethylglycine, dipotassium glycyrrhizinate, acesulfame potassium, sodium benzoate and sodium lauroyl sarcosinate in water; uniformly mixing calcium hydrogen phosphate, aluminum hydroxide and sodium lauryl sulfate, spraying the water phase into the powder while stirring, finally spraying the essence dissolving perillaseed into the powder while stirring, conveying the powder to a grinding machine for grinding uniformly until no particles are observed visually, sieving with a 150-mesh sieve, and packaging.

Clinical trial part

1. Oral mucosa irritation test for animals

First test group: 5 healthy and early-adult golden yellow hamster are selected, the same strain is male and female, the test sample is the original toothpaste sample of the example 1, and the negative control sample is 0.9% sodium chloride injection.

Second test group: 5 healthy and early-adult golden yellow hamster are selected, the same strain is male and female, the test sample is a blank toothpaste original sample without the puncture reducing composition, and the negative control sample is 0.9% sodium chloride injection.

Placing a sample (diameter is not more than 5mm) into the buccal pouch of one side of golden yellow hamster, taking the other side as a control sample, taking the sample once a day, 5 minutes each time, 21 days continuously, removing coating after each contact, flushing the buccal pouch with physiological saline, carrying out visual observation and recording the change of buccal pouch mucous epithelium and crusted hoof tissues, adding each observation score, dividing the obtained sum by the observed total number to obtain the average score of each animal, scoring according to the oral reaction scoring system specified in table 1, carrying out visual observation on the buccal pouch 24 hours after the last contact, killing the mice painlessly, taking a tissue sample of the representative part of the buccal pouch, placing the tissue sample into a proper fixing solution for fixing, carrying out histopathological evaluation, evaluating the stimulation reaction of oral tissues by a microscope, scoring each tissue according to the scoring system specified in table 2, adding the microscopic evaluation scores of all animals in the test group, and dividing the obtained result by the observed total number, the average score of the test group is obtained, the average score of the control group is calculated by the same method, and the maximum score is 16. The mean scores of the test groups were subtracted from the mean scores of the control groups to give the stimulation index (see table 3).

TABLE 1 oral reaction visual scoring System

Reaction (erythema and eschar formation)	Score recording
		No erythema	0
Extremely slight erythema (barely visible)	1
		Clear erythema	2
Moderate erythema	3
		Severe erythema (mauve) to eschar formation	4

TABLE 2 tissue response microscopy scoring system

TABLE 3 irritation index

Stimulation index	Extent of reaction
		0	Is free of
1～4	Is extremely light
		5～8	Mild degree of
9～11	Of moderate degree
		12～16	Severe degree

The average scores for visual inspection are shown in table 4:

TABLE 4 average score by visual inspection

	Average score of negative control group	Mean score of test sample groups
			First test group	0.2	0.4
Second test group	0.2	0.8

From table 4, it is known that: there was no significant difference between the buccal mucosal epithelial tissues of the control group and the test sample group in the first test group, and there was a significant difference between the buccal mucosal epithelial tissues of the control group and the test sample group in the second test group.

The average histopathological observation scores are shown in table 5:

TABLE 5 average histopathological Scoring

From table 5, it is known that: the control group in the first test group had intact epithelial tissue, no leukocyte infiltration and edema, essentially no vascular congestion, and a mean score of 0.4. The test group showed histological appearance similar to the control group, with an average score of 0.6, a stimulation index of 0.2 and no irritation of the toothpaste of example 1.

The control group in the second test group had intact epithelial tissue, no leukocyte infiltration and edema, essentially no vascular congestion, and a mean score of 0.4. The test group had intact epithelial tissue, no leukocyte infiltration, essentially no vascular congestion, minimal edema, an average score of 1.0, a stimulation index of 0.6, and no irritation in the blank toothpaste without the irritation-reducing composition.

As shown by animal oral mucosa irritation tests, the toothpaste containing the irritation-reducing composition has a good effect of obviously reducing irritation of the product, and by analogy, the oral care product containing the irritation-reducing composition also has a good effect of reducing irritation of the product, so that the expected purpose is achieved.

2. Taste testing

The effect of the toothpaste prepared in example 3 on the improvement of mouthfeel was evaluated: 30 oral care product investigators with professional training of a company are selected as trial objects, the subjects brush the teeth twice in the morning and at night, and questionnaires are evaluated after trial for 10 days, and the results are shown in table 6.

TABLE 6 toothpaste taste questionnaire

The investigation result is unexpectedly satisfactory, and the overall mouthfeel is generally reflected by a test person to be particularly good, particularly the feeling after use is more obvious, the oral cavity is particularly mild and moist after use, and the oral cavity has no bad feeling of drying after use of the commercial toothpaste. The composition has important effects on reducing the irritation of the product and improving the mouthfeel of the product.

The above embodiments are merely illustrative and not restrictive, and modifications may be made to the embodiments without departing from the spirit and scope of the present invention.

Claims

1. Use of a reduced irritation composition in the manufacture of an oral care product, characterized by: the thorn-reducing composition consists of three components of trimethylglycine, perillaseed and dipotassium glycyrrhizinate; the addition amount of the trimethylglycine is 1.0-5.0%, the addition amount of the perillaseed is 0.002-0.02%, and the addition amount of the dipotassium glycyrrhizinate is 0.05-0.5%; the total amount of the thorn-reducing composition in the oral care product is controlled within 11.0%.

2. Use of a spur-reducing composition according to claim 1 in the manufacture of an oral care product, wherein: the total addition amount of the thorn-reducing composition in the preparation of the oral care product is within 5.5 percent.

3. Use of a spur-reducing composition according to claim 1 in the manufacture of an oral care product, wherein: the oral care product is one of toothpaste, mouthwash and dentifrice products.

4. An oral care product comprising a reduced irritation composition characterized by: the oral care product is toothpaste which is composed of the following raw material components in percentage by weight:

5. The oral care product containing a spur-reducing composition according to claim 4, wherein:

the abrasive is one or a mixture of two of calcium carbonate, calcium hydrophosphate, silicon dioxide and aluminum hydroxide;

the humectant is one or a mixture of sorbitol, glycerol, polyethylene glycol and propylene glycol;

the thickening agent is one or a mixture of more of sodium carboxymethylcellulose, xanthan gum, guar gum and carrageenan;

the surfactant is one or more of sodium lauryl sulfate, sodium lauroyl sarcosinate and cocamidopropyl betaine;

the sweetener is one or a mixture of saccharin sodium and acesulfame potassium;

the preservative is one or a mixture of two of sodium benzoate and nipagin ester.

6. An oral care product comprising a reduced irritation composition characterized by: the oral care product is a mouthwash, and the mouthwash is composed of the following raw material components in percentage by weight:

7. The oral care product containing a spur-reducing composition according to claim 6, wherein:

the humectant is one or a mixture of sorbitol, glycerol and propylene glycol;

the surfactant is one or more of tween, poloxamer and PEG-40 hydrogenated castor oil;

the sweetener is one or two of saccharin sodium, sucralose and thaumatin;

the preservative is one or a mixture of sodium benzoate and nipagin ester;

the collutory may also contain ethanol, xylitol, etc.

8. An oral care product comprising a reduced irritation composition characterized by: the oral care product is dentifrice which is prepared from the following raw materials in percentage by weight:

9. The oral care product containing a spur-reducing composition according to claim 8, wherein:

the sweetener is one or a mixture of saccharin sodium and acesulfame potassium;