CN107801724A - Bactericidal composition and its application - Google Patents
Bactericidal composition and its application Download PDFInfo
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- CN107801724A CN107801724A CN201611140988.7A CN201611140988A CN107801724A CN 107801724 A CN107801724 A CN 107801724A CN 201611140988 A CN201611140988 A CN 201611140988A CN 107801724 A CN107801724 A CN 107801724A
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- amine
- thiophene
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
- A01N47/14—Di-thio analogues thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/82—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
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- General Health & Medical Sciences (AREA)
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention provides a kind of bactericidal composition and its application, belongs to agriculture chemical compounding field.The bactericidal composition, active ingredient are that first thiophene lures amine (A) and protective fungicide (B), and the weight ratio of (A) and (B) is 70：1‑1：70 protective fungicides (B) are Carbatene, ambam, zineb or Propineb.Active ingredient (A) has obvious synergistic effect with (B) compounding, can effectively reduce the amount of application of each single dose.Said composition can add the auxiliary element for allowing to use in remaining agricultural chemicals and be processed into any formulation.The bactericidal composition is mainly used in preventing and treating the fungus diseases such as black heart, early blight of tomato, rice blast, wheat powdery mildew, sigatoka.
Description
Technical field
The present invention relates to a kind of bactericidal composition, particularly relates to a kind of compounding that amine and protective fungicide are lured containing first thiophene
Microbicide compositions and its application.
Background technology
Agricultural chemicals has played great function, but not science with fast and effective and lower-price characteristic in agricultural is increased production without increasing the work force
Medication and single drug already lead to germ drug-fast constantly enhancing and pvs oryzae and oryzicola and are continuously increased, meanwhile, frequently make
Financial burden is also increased with agricultural chemicals, and result in environmental pollution and a series of serious ecological problems of agricultural product security and society
Problem.With the continuous improvement of people's living standards, concern to environmental protection, safety and quality to agricultural product are proposed
Higher requirement.Therefore, how Scientific Usage of Drugs, reduce the dosage of chemical pesticide, improve drug effect, turn into plant protection art urgent need
The problem of solution.
It is a kind of thiadiazole Plant activator that first thiophene, which lures amine, the general entitled N- of chemistry (5- methyl isophthalic acids, 3- thiazoles-
2- yls) -4- methyl isophthalic acids, 2,3- thiadiazoles -5- formamides, its structural formula is such as shown in (I).Current result of study shows, the change
Compound has induction disease resisting effect well to virus disease, and mechanism of action is the disease-resistant work of induction plant generation system, wide spectrum
Property.Plant disease-proof activator is a kind of novel agricultural chemicals to receive much concern in recent years, itself has no obvious bactericidal activity, but
Immunoactivator of the energy as plant, inducer of systemic acquired resistance, so as to reach the purpose of defending and fighting against diseases.Wherein, BTH
(diazosulfide, the production of Syngenta Co., Ltd of Switzerland) and TDL (tiadinil, Nihon Nihyaku Co., Ltd's production) are such medicament
Representative Cultivars, widely applied in agricultural production at present.Because first thiophene lures amine single dose to belong to activating plants agent, mainly
Resistance to disease is produced by the system of plant, but the plant to having fallen ill is without good therapeutic action.
Its structural formula of Carbatene is a kind of excellent protective fungicide, belongs to low-toxin farm chemicals such as shown in (II).Because it is killed
Bacterium scope is wide, is not likely to produce resistance, and prevention effect is substantially better than other same series bactericidal agents, so dosage is always big in the world
Volume production.It is the substitute products of other current protective fungicides, domestic most composite bactericides are all processed with Mancozeb
It is formulated, but MnZn preparation can cause crop trace element accumulation poisoning, by Field information in recent years, to preventing and treating the black star of pears
Disease, alternaria leaf spot of apple, vegetable category epidemic disease, downy mildew, field crop rust and other effects are notable.
Its structural formula of Mancozeb is a kind of excellent protective fungicide, belongs to low-toxin farm chemicals such as shown in (III).Due to it
Bactericidal range is wide, is not likely to produce resistance, and prevention effect is substantially better than other same series bactericidal agents, so dosage is always in the world
Large tonnage product.At present, domestic most composite bactericides are all formulated with Mancozeb processing, and manganese, zinc microelement are to making
Thing has obvious rush to strengthen, production-increasing function, by more than ten years Field information, to preventing and treating pear scab, alternaria leaf spot of apple, melon dish
Class epidemic disease, downy mildew, field crop rust and other effects are notable, effectively disease can be controlled to send out completely without other any bactericide
It is raw, it is steady quality, reliable.
Its structural formula of ambam belongs to organic sulphur preparation such as shown in (IV).Sterling is colourless crystallization, water-soluble.Industrial goods
For weak yellow liquid, in neutral or alkalescent, there is rotten-egg odour.Chemical property is relatively stable, but easy after the high temperature more than 40 DEG C
Decompose.Ambam controlling disease mainly shields, and because decoction can penetrate into plant epidermis, has therapeutic action concurrently again.To people
Poultry low toxicity.Main formulation 45%, the 50% ambam aqueous solution.
Its structural formula of zineb is protectiveness organosulfureous fungicide such as shown in (V).Sterling is pale powder, industrial goods
For canescence or pale yellow powder, there is sulfur-containing aroma.It is unstable under the conditions of alkalescence, high temperature, humidity, day illumination are shone.To people and animals
Low toxicity, but have stimulation to the skin, nose, throat of people.To plant safety non-pollution.Zineb is safe to plant, chemically
Matter work ripple, is easily oxidized to different thiocyanation compound in water, has strong suppression to make the enzyme for containing-SH bases in pathogen body
With, and germ spore can be directly killed, suppress the germination of spore, prevent in germ invaded plantses body, but in invaded plantses body
The mycelial lethal effect of cause of disease it is smaller.
Its structural formula of Propineb is a kind of wide spectrum, quick-acting protective fungicides such as shown in (VI).Alias：Safe and sound life.System
Agent：70% Wettable propineb powder.Physicochemical property：70% Wettable propineb powder is cream-coloured powder.With special gas
Taste, density 0.28, pH5.2, suspension stability are more than 75%, and MEBO ribbon gauze is less than 120 seconds, and water content is less than 2.5%, normal temperature storage
Deposit stability more than 2 years.Toxicity：By Chinese pesticide toxicity grading criteria, Propineb belongs to less toxic bactericide.It is nontoxic to honeybee.Make
Use mechanism：The bactericidal mechanism of Propineb is the oxidation for suppressing pyruvic acid in pathogen body.
The content of the invention
For the above situation, the present invention provides a kind of bactericidal composition and its application, to meet the needs of agricultural production, group
Active component included in compound has mutually synergistic effect to improve preventive effect and is beneficial to delay the drug-fast generation of germ.
The bactericidal composition of the present invention, its active ingredient are that first thiophene lures amine and protective fungicide, and first thiophene lures amine and protection
Property bactericide weight ratio be 70：1-1：70, preferable ratio is 30：1-1：30, preferably 15：1-1：15, remaining is in agricultural chemicals
Allow to use and acceptable auxiliary element.
Protective fungicide of the present invention is more preferably any in Carbatene, ambam, zineb or Propineb
It is a kind of.
In the composition of the present invention auxiliary agent that uses include wetting agent, dispersant, emulsifying agent, solvent and filler etc. and its
He is beneficial to the known substance that active ingredient is stablized in the formulation and drug effect plays, and is all to commonly use in pesticidal preparations or allow to use
Various composition, have no specific restriction, possess composition and dosage and determined according to recipe requirements by simple experiment.
The bactericidal composition of the present invention can be prepared into any one formulation of suitable agricultural use with known method, than
Preferable formulation is wettable powder, soluble powder, aqua, suspending agent, microemulsion or water dispersible granules.
Composition described in the invention can be provided in the form of finished product preparation, i.e., each material is blended in composition,
The composition of composition can also be provided with unit dose form, directly mixed, be then diluted to required in bucket or tank using preceding
Concentration.
The multiple diseases that the bactericidal composition of the present invention can be used on the crops such as preventing and treating rice, wheat, vegetables, fruit tree are especially
It is suitable for preventing and treating the plant diseases such as black heart, downy mildew, anthracnose, powdery mildew, rice blast, early blight.The present invention's
Composition can be applied by common method, such as cast, injection, spraying, dusting or spread, and its amount of application is with weather condition or work
Thing state change.
Compared with prior art, the beneficial effects of the present invention are：1st, compared with single dose, there is compounding obvious collaboration to increase
Effect acts on, and improves prevention effect；2nd, composition is made up of two kinds of different active ingredients of mechanism of action, is advantageous to overcome and is prolonged
The drug-fast generation of slow germ；3rd, composite reagent reduces dosage, so as to reduce cost and alleviate the pollution to environment；
4th, compared with bactericide is used alone, producing the risk of poisoning reduces.
Below equation calculating is used in experiment：
Calculate inhibiting rate of the medicament to germ.Then inhibiting rate is changed into probit value (y), concentration changes into logarithm value
(x) toxicity regression curve equation y=a+bx of each medicament to germ, and concentration EC effectively in suppression, are obtained50Value and phase relation
Number r.
The co-toxicity coefficient (CTC values) of mixture is calculated by formula (1), formula (2), formula (3)：
In formula：ATI-mixture actual measurement toxicity index；
The LC of S-standard antiseptic agent50, unit is milligrams per liter (mg/L)；
The LC of M-mixture50, unit is milligrams per liter (mg/L).
TTI=A × PA+B×PB························(2)
In formula：TTI-mixture theoretical toxicity index；
A-A medicament toxicity index；
PAPercentage composition of-A the medicaments in mixture, unit are percentage (%)；
B-B medicament toxicity index；
PBPercentage composition of-B the medicaments in mixture, unit are percentage (%).
In formula：CTC-co-toxicity coefficient.
The co-toxicity coefficient (CTC) >=120 of complex preparation shows as synergistic effect；CTC≤80 show as antagonism；80 ﹤
CTC ﹤ 120 show as summation action.
Embodiment
To make embodiments of the invention technical problems to be solved, technical scheme and advantage clearer, below by apparatus
Body embodiment is described in detail, but the present invention is limited to absolutely not these examples.As described below is only the preferable embodiment of the present invention,
Only to explain the present invention, the limitation to the scope of the claims of the present invention therefore can not be interpreted as.It should be pointed out that it is all
All any modification, equivalent and improvement done within the spirit and principles in the present invention etc., it should be included in the protection of the present invention
Within the scope of.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Agricultural chemicals is made in the combination of active principles of different agricultural chemicals, is current exploitation and develops novel pesticide and preventing and treating agriculturally
A kind of effective and quick way of resistance germ.After the pestsides synthesis of different cultivars, a large amount of three kinds of effects classes are typically exhibited
Type：Summation action, synergistic effect and antagonism.The good composite formula of compound synergic, can significantly improve actual preventing and treating
Effect, the usage amount of agricultural chemicals is reduced, be the important of integrated control disease so as to help to delay the drug-fast generation speed of germ
Means.
When two kinds of bactericide selecting of the present invention lure amine for effective constituents A first thiophene, active ingredient B be Carbatene, ambam,
Zineb or Propineb, there is good synergistic effect, rather than just the simple superposition of two kinds of medicaments.
In order to prevent and treat the important disease on the crops such as corn in agricultural production, rice, wheat, inventor is with rice blast
The synergy for luring first thiophene amine and Carbatene, ambam, zineb or Propineb to be compounded for experiment disease is studied, and screens first
Thiophene lures the optimum proportioning amount ranges of amine and Carbatene, ambam, zineb or Propineb, the preventing and treating for field diseases.
First thiophene lures the indoor harmacological effect determination test of amine and Carbatene compounding to sigatoka：
For trying pathogen：Sigatoka bacterium
Test method：Using live body method, each processing is repeated 5 times, and lesion diameter is measured after 6d, calculates EC50With common poison
Coefficient, result of the test are shown in Table 1.
Table 1
Note：Co-toxicity coefficient CTC >=120 indicate synergistic effect, and 80 ＜ CTC ＜ 120 represent summation action, the table of CTC≤80
It is shown with antagonism.
Toxicity Determination result is shown, in weight than 70：1-1：70, particularly 30：1-1：30, especially 15：1-
1：In the range of 15, first thiophene lures amine and Carbatene compounding has obvious synergistic effect, the synergy effect of compounding to sigatoka
Fruit becomes apparent, and prevention effect is excellent and is better than single dose kind.
First thiophene lures the indoor harmacological effect determination test of amine and ambam compounding to wheat powdery mildew, and result of the test is shown in Table 2.
Table 2
| Reagent agent | EC50 | Regression equation | CTC |
| First thiophene lures amine (A) | 43.01 | Y=2.7510+1.3767X | —— |
| Ambam (B) | 26.64 | Y=2.8536+1.5057X | —— |
| (A：B)70：1 | 31.57 | Y=2.6401+1.5740X | 135.1 |
| 30：1 | 29.88 | Y=2.4383+1.7363X | 141.2 |
| 15：1 | 24.92 | Y=2.2812+1.9467X | 166.2 |
| 1：1 | 21.19 | Y=2.5798+1.8250X | 155.3 |
| 1：15 | 20.68 | Y=2.7320+1.7241X | 132 |
| 1：30 | 20.88 | Y=2.8491+1.6299X | 129.2 |
| 1：70 | 21.92 | Y=2.8680+1.5900X | 122.2 |
Note：Co-toxicity coefficient CTC >=120 indicate synergistic effect, and 80 ＜ CTC ＜ 120 represent summation action, the table of CTC≤80
It is shown with antagonism.
Toxicity Determination result is shown, in weight than 70：1-1：70, particularly 30：1-1：30, especially 15：1-
1：In the range of 15, first thiophene lures amine and ambam compounding has obvious synergistic effect, the synergy effect of compounding to wheat powdery mildew
Fruit becomes apparent, and prevention effect is excellent and is better than single dose kind.
First thiophene lures the indoor harmacological effect determination test of amine and zineb compounding to cucumber downy mildew, and result of the test is shown in Table 3.
Table 3
| Reagent agent | EC50 | Regression equation | CTC |
| First thiophene lures amine (A) | 42.92 | Y=2.7459+1.3806X | —— |
| Zineb (B) | 26.38 | Y=2.8752+1.4949X | —— |
| (A：B)70：1 | 30.79 | Y=1.9345+2.0594X | 138.2 |
| 30：1 | 28.99 | Y=1.9247+2.1030X | 145.1 |
| 15：1 | 26.23 | Y=2.0430+2.0842X | 157.5 |
| 1：1 | 21.57 | Y=2.3958+1.9524X | 151.5 |
| 1：15 | 22.37 | Y=2.8034+1.6276X | 120.9 |
| 1：30 | 22.05 | Y=3.1143+1.4036X | 121.1 |
| 1：70 | 22.10 | Y=3.1084+1.4070X | 120 |
Note：Co-toxicity coefficient CTC >=120 indicate synergistic effect, and 80 ＜ CTC ＜ 120 represent summation action, the table of CTC≤80
It is shown with antagonism.
Toxicity Determination result is shown, in weight than 70：1-1：70, particularly 30：1-1：30, especially 15：1-
1：In the range of 15, first thiophene lures amine and zineb compounding has obvious synergistic effect, the synergy effect of compounding to cucumber downy mildew
Fruit becomes apparent, and prevention effect is excellent and is better than single dose kind.
First thiophene lures the indoor harmacological effect determination test of amine and Propineb compounding to early blight of tomato, and result of the test is shown in Table 4.
Table 4
Note：Co-toxicity coefficient CTC >=120 indicate synergistic effect, and 80 ＜ CTC ＜ 120 represent summation action, the table of CTC≤80
It is shown with antagonism.
Toxicity Determination result is shown, in weight than 70：1-1：70, particularly 30：1-1：30, especially 15：1-
1：In the range of 15, first thiophene lures amine and Propineb compounding has obvious synergistic effect, the synergy effect of compounding to early blight of tomato
Fruit becomes apparent, and prevention effect is excellent and is better than single dose kind.
The bactericidal composition of the present invention can be prepared into any one formulation of suitable agricultural use with known method, than
Preferable formulation is wettable powder, soluble powder, suspending agent, aqua, microemulsion or water dispersible granules.Hundred in all formulas
Ratio is divided to be weight percentage.The processing technology of the various formulations of the present composition is prior art, can according to different situations
To be varied from.
Embodiment 1：71% first thiophene lures amine Carbatene suspending agent
Component：First thiophene lures amine 1%, Carbatene 70%, methyl naphthalene sulfonate formaldehyde condensate 1%, sodium lignin sulfonate
3%, xanthan agent 2%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation method：Each component is mixed, is well mixed through high speed shear, then 2-3 hours are sanded by sand mill, makes to put down
Equal particle diameter reaches 1-5 microns, you can 51% first thiophene is made and lures amine mancozeb suspending agent.
Embodiment 2：51% first thiophene lures amine thioneb wettable powder
Component：First thiophene lures amine 1%, Carbatene 50%, neopelex 6%, lignin sodium naphthalene sulfonate 12%, in vain
Carbon black 25%, talcum powder complements to 100%.
Preparation method：Each component is well mixed, by mechanical crushing, then after air-flow crushing, is well mixed, you can
31% first thiophene is made and lures amine mancozeb wettable powder.
Embodiment 3：31% first thiophene lures amine Carbatene oil-suspending agent
Component：First thiophene lures amine 1%, Carbatene 30%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：Active compound, emulsifying agent, Ricinate, organobentonite and methyl oleate etc. are weighed by formula rate
Each component is standby, through high speed shear mixing with, then 2-3h is sanded by sand mill, makes its average grain diameter in 2-5 microns,
Both obtain 26% first thiophene and lure amine Mancozeb oil-suspending agent.
Embodiment 4：16% first thiophene lures amine Carbatene microemulsion
Component：First thiophene lures amine 1%, Carbatene 15%, nonionic surfactant agriculture breast 600#3%, anionic surface work
Property agent agriculture breast 500#3%, dimethylbenzene 1%, methanol 5%, water supply 100%.
Preparation method：Emulsifying agent and pesticide original medicine are mixed to form solution, other solvents are added, in high-speed stirred condition
In lower instillation water, transparent o/w type microemulsions are formed.
Embodiment 5：2% first thiophene lures amine Carbatene oil-suspending agent
Component：First thiophene lures amine 1%, Carbatene 1%, calcium dodecyl benzene sulfonate 4%, NPE 6%, castor
Sesame oil APEO 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 6：16% first thiophene lures amine Carbatene oil-suspending agent
Component：First thiophene lures amine 15%, Carbatene 1%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 7：31% first thiophene lures amine Carbatene suspending agent
Component：First thiophene lures amine 30%, Carbatene 1%, methyl naphthalene sulfonate formaldehyde condensate 1%, sodium lignin sulfonate
3%, xanthan agent 2%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 8：51% first thiophene lures amine Carbatene water dispersible granules
Component：First thiophene lures amine 50%, Carbatene 1%, Negel 5%, sodium lignin sulfonate 7%, dodecyl
Sodium sulfonate 2%, ammonium sulfate 5%, kaolin complementary.
Preparation method：Each component is well mixed, obtains mixture, mixture, again through air-flow crushing, obtains through mechanical crushing
To secondary mixture, secondary mixture quality 10%-15% water is added into secondary mixture, is well mixed, then through extruding
It is granulated, forms column or spherical particle, be finally dried, that is, obtain 31% first thiophene and lure amine Mancozeb water-dispersible grain
Agent.
Embodiment 9：71% first thiophene lures amine Carbatene microemulsion
Component：First thiophene lures amine 70%, Carbatene 1%, nonionic surfactant agriculture breast 600#3%, anionic surface work
Property agent agriculture breast 500#3%, dimethylbenzene 1%, methanol 5%, water supply 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 10：71% first thiophene lures amine zineb oil-suspending agent
Component：First thiophene lures amine 1%, zineb 70%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 11：51% first thiophene lures amine zineb oil-suspending agent
Component：First thiophene lures amine 1%, zineb 50%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 12：31% first thiophene lures amine zineb microemulsion
Component：First thiophene lures amine 1%, zineb 30%, nonionic surfactant agriculture breast 600#3%, anionic surface work
Property agent agriculture breast 500#3%, dimethylbenzene 1%, methanol 5%, water supply 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 13：16% first thiophene lures amine zineb microemulsion
Composition：First thiophene lures amine 1%, zineb 15%, nonionic surfactant agriculture breast 600#3%, anionic surface work
Property agent agriculture breast 500#3%, dimethylbenzene 1%, methanol 5%, water supply 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 14：2% first thiophene lures amine zineb suspending agent
Composition：First thiophene lures amine 1%, zineb 1%, methyl naphthalene sulfonate formaldehyde condensate 1%, sodium lignin sulfonate 3%,
Xanthan agent 2%, bentonite 1%, glycerine 5%, water complements to 100%.Preparation method：With the preparation side of above-mentioned equal formulation
Method.
Embodiment 15：16% first thiophene lures amine zineb oil-suspending agent
Composition：First thiophene lures amine 15%, zineb 1%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 16：31% first thiophene lures amine zineb suspending agent
Composition：First thiophene lures amine 30%, zineb 1%, methyl naphthalene sulfonate formaldehyde condensate 1%, sodium lignin sulfonate
3%, xanthan agent 2%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 17：51% first thiophene lures amine zineb suspending agent
Composition：First thiophene lures amine 50%, zineb 1%, methyl naphthalene sulfonate formaldehyde condensate 1%, sodium lignin sulfonate
3%, xanthan agent 2%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 18：71% first thiophene lures amine water dispersion granules agent of dithane
Component：First thiophene lures amine 70%, zineb 1%, Negel 5%, sodium lignin sulfonate 7%, dodecyl
Sodium sulfonate 2%, ammonium sulfate 5%, kaolin complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 19：71% first thiophene lures amine Propineb oil-suspending agent
Composition：First thiophene lures amine 1%, Propineb 70%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 20：51% first thiophene lures amine Propineb oil-suspending agent
Composition：First thiophene lures amine 1%, Propineb 50%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 21：31% first thiophene lures amine Propineb microemulsion
Composition：First thiophene lures amine 1%, Propineb 30%, nonionic surfactant agriculture breast 600#3%, anionic surface work
Property agent agriculture breast 500#3%, dimethylbenzene 1%, methanol 5%, water supply 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 22：16% first thiophene lures amine Propineb microemulsion
Component：First thiophene lures amine 1%, Propineb 15%, nonionic surfactant agriculture breast 600#3%, anionic surface work
Property agent agriculture breast 500#3%, dimethylbenzene 1%, methanol 5%, water supply 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 23：2% first thiophene lures amine Propineb suspending agent
Composition：First thiophene lures amine 1%, Propineb 1%, methyl naphthalene sulfonate formaldehyde condensate 1%, sodium lignin sulfonate 3%,
Xanthan agent 2%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 24：16% first thiophene lures amine Propineb oil-suspending agent
Composition：First thiophene lures amine 15%, Propineb 1%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 25：31% first thiophene lures amine Propineb suspending agent
Composition：First thiophene lures amine 30%, Propineb 1%, methyl naphthalene sulfonate formaldehyde condensate 1%, sodium lignin sulfonate
3%, xanthan agent 2%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 26：51% first thiophene lures amine Propineb suspending agent
Composition：First thiophene lures amine 50%, Propineb 1%, methyl naphthalene sulfonate formaldehyde condensate 1%, sodium lignin sulfonate
3%, xanthan agent 2%, bentonite 1%, glycerine 5%, water complements to 100%.Preparation method：With the preparation of above-mentioned equal formulation
Method.
Embodiment 27：71% first thiophene lures amine Propineb water dispersible granules
Composition：First thiophene lures amine 70%, Propineb 1%, Negel 5%, sodium lignin sulfonate 7%, dodecyl
Sodium sulfonate 2%, ammonium sulfate 5%, kaolin complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 28：71% first thiophene lures amine ambam oil-suspending agent
Composition：First thiophene lures amine 1%, ambam 70%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 29：51% first thiophene lures amine ambam oil-suspending agent
Composition：First thiophene lures amine 1%, ambam 50%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 30：31% first thiophene lures amine ambam microemulsion
Composition：First thiophene lures amine 1%, ambam 30%, nonionic surfactant agriculture breast 600#3%, anionic surface work
Property agent agriculture breast 500#3%, dimethylbenzene 1%, methanol 5%, water supply 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 31：16% first thiophene lures amine ambam microemulsion
Component：First thiophene lures amine 1%, ambam 15%, nonionic surfactant agriculture breast 600#3%, anionic surface work
Property agent agriculture breast 500#3%, dimethylbenzene 1%, methanol 5%, water supply 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 32：2% first thiophene lures amine Propineb suspending agent
Composition：First thiophene lures amine 1%, Propineb 1%, methyl naphthalene sulfonate formaldehyde condensate 1%, sodium lignin sulfonate 3%,
Xanthan agent 2%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 33：16% first thiophene lures amine ambam oil-suspending agent
Composition：First thiophene lures amine 15%, ambam 1%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 34：31% first thiophene lures amine ambam suspending agent
Composition：First thiophene lures amine 30%, ambam 1%, methyl naphthalene sulfonate formaldehyde condensate 1%, sodium lignin sulfonate
3%, xanthan agent 2%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 35：51% first thiophene lures amine ambam suspending agent
Composition：First thiophene lures amine 50%, ambam 1%, methyl naphthalene sulfonate formaldehyde condensate 1%, sodium lignin sulfonate
3%, xanthan agent 2%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Embodiment 36：71% first thiophene lures amine ambam water dispersible granules
Composition：First thiophene lures amine 70%, ambam 1%, Negel 5%, sodium lignin sulfonate 7%, dodecyl
Sodium sulfonate 2%, ammonium sulfate 5%, kaolin complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Comparative example 1：31% first thiophene lures amine Bordeaux mixture microemulsion
Composition：First thiophene lures amine 1%, Bordeaux mixture 30%, nonionic surfactant agriculture breast 600#3%, anionic surface
Activating agent agriculture breast 500#3%, dimethylbenzene 1%, methanol 5%, water supplies 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Comparative example 2,2% first thiophene lure amine Mancozeb oil-suspending agent
Component：First thiophene lures amine 1%, Mancozeb 1%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Comparative example 3：2% first thiophene lures amine Bordeaux mixture oil-suspending agent
Component：First thiophene lures amine 1%, Bordeaux mixture 1%, calcium dodecyl benzene sulfonate 4%, NPE 6%,
Castor oil polyoxyethylene ether 5%, organobentonite 1.5%, methyl oleate complementary.
Preparation method：With the preparation method of above-mentioned equal formulation.
Comparative example 4,31% first thiophene lure amine mancozeb suspending agent
Component：First thiophene lures amine 30%, Mancozeb 1%, methyl naphthalene sulfonate formaldehyde condensate 1%, sodium lignin sulfonate
3%, xanthan agent 2%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation method：With the preparation method of above-mentioned equal formulation.
Pesticidal preparations rice blast made from above-described embodiment and comparative example is tested
Test process：Experiment is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).This experiment
Dosing sets three concentration for the treatment of respectively according to the difference of each composition, and comparison medicament is that the commercially available first thiophene of agricultural chemicals 6% lures respectively
Amine suspending agent and the control of 70% Carbatene suspending agent and clear water.
Test method：Each plot area is 50cm2, it is repeated 4 times, the inspection drug effect method after investigating and preventing and treating before dispenser
For：Taken a little per cell diagonal, every is extracted 10 plants of investigation, account for whole blade area with the lesion area on every plant of blade hundred
Point rate is classified, and result of the test see the table below 5：
The first thiophene of table 5 lures the prevention effect of amine and Carbatene compounding to rice blast
The field efficacy result of table 5 shows, in weight than 1：70-70：In the range of 1, first thiophene lures amine and Carbatene compound synergic
Positive effect, particularly 1：30-30：1 scope, especially 15：1-1：In the range of 15, there is excellent preventing and treating to rice blast
Effect, prevention effect is better than single dose kind, and prevention effect is better than first thiophene and lures amine and other protective fungicide (such as maneb
Zinc, Bordeaux mixture) compounding.
Pesticidal preparations cucumber downy mildew made from above-described embodiment and comparative example is tested
Test process：Experiment is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).This experiment
Dosing sets three concentration for the treatment of respectively according to the difference of each composition, and comparison medicament is that the commercially available first thiophene of agricultural chemicals 6% lures respectively
Amine suspending agent and the control of 65% zineb and clear water.
Test method：Each plot area is 50cm2, it is repeated 4 times, the inspection drug effect method after investigating and preventing and treating before dispenser
For：Taken a little per cell diagonal, every is extracted 10 plants of investigation, account for whole blade area with the lesion area on every plant of blade hundred
Point rate is classified, and result of the test see the table below 6：
The first thiophene of table 6 lures the prevention effect of amine and zineb compounding to cucumber downy mildew
The field efficacy result of table 6 shows, in weight than 1：70-70：In the range of 1, first thiophene lures amine and zineb compound synergic
Positive effect, particularly 1：30-30：1 scope, especially 15：1-1：In the range of 15, there is excellent preventing and treating to cucumber downy mildew
Effect, prevention effect is better than single dose kind, and prevention effect is better than first thiophene and lures amine and other protective fungicide (such as maneb
Zinc, Bordeaux mixture) compounding.
Pesticidal preparations early blight of tomato made from above-described embodiment and comparative example is tested
Test process：Experiment is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).This experiment
Dosing sets three concentration for the treatment of respectively according to the difference of each composition, and comparison medicament is that the commercially available first thiophene of agricultural chemicals 6% lures respectively
Amine suspending agent and the control of 70% Propineb and clear water.
Test method：Each plot area is 50cm2, it is repeated 4 times, the inspection drug effect method after investigating and preventing and treating before dispenser
For：Taken a little per cell diagonal, every is extracted 10 plants of investigation, account for whole blade area with the lesion area on every plant of blade hundred
Point rate is classified, and result of the test see the table below 7：
The first thiophene of table 7 lures the prevention effect of amine and Propineb compounding to early blight of tomato
The field efficacy result of table 7 shows, in weight than 1：70-70：In the range of 1, first thiophene lures amine and Propineb compound synergic
Positive effect, particularly 1：30-30：1 scope, especially 15：1-1：In the range of 15, there is excellent preventing and treating to cucumber virosis
Effect, prevention effect is better than single dose kind, and prevention effect is better than first thiophene and lures amine and other protective fungicide (such as maneb
Zinc, Bordeaux mixture) compounding.
Pesticidal preparations wheat powdery mildew made from above-described embodiment and comparative example is tested
Test process：Experiment is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).This experiment
Dosing sets three concentration for the treatment of respectively according to the difference of each composition, and comparison medicament is that the commercially available first thiophene of agricultural chemicals 6% lures respectively
Amine suspending agent and the control of 43% ambam and clear water.
Test method：Each plot area is 50cm2, it is repeated 4 times, the inspection drug effect method after investigating and preventing and treating before dispenser
For：Taken a little per cell diagonal, every is extracted 10 plants of investigation, account for whole blade area with the lesion area on every plant of blade hundred
Point rate is classified, and result of the test see the table below 8：
The first thiophene of table 8 lures the prevention effect of amine and ambam compounding to wheat powdery mildew
The field efficacy result of table 8 shows, in weight than 1：70-70：In the range of 1, first thiophene lures amine and ambam compound synergic
Positive effect, particularly 1：30-30：1 scope, especially 15：1-1：In the range of 15, there is excellent preventing and treating to wheat powdery mildew
Effect, prevention effect is better than single dose kind, and prevention effect is better than first thiophene and lures amine and other protective fungicide (such as maneb
Zinc, Bordeaux mixture) compounding.
Pesticidal preparations preventing and treating rice blast, wheat powdery mildew, cucumber downy mildew made from above-described embodiment and comparative example
The field control effectiveness test result of the diseases such as disease shows that first thiophene lures amine and Carbatene, ambam, zineb or Propineb in the present invention
Weight than 70：1-1：It is 30 to have certain Complex synergism, particularly weight ratio in the range of 70：1-1：30, especially
15：1-1：In the range of 15, after first thiophene lures amine and Carbatene, ambam, zineb or Propineb compounding, to disease-controlling effect
Excellent, compared with bactericide single dose, Complex synergism is obvious, can effectively preventing disease.
Described above is the preferred embodiment of the present invention, it is noted that for those skilled in the art
For, on the premise of principle of the present invention is not departed from, some improvements and modifications can also be made, these improvements and modifications
It should be regarded as protection scope of the present invention.
Claims (9)
- A kind of 1. bactericidal composition, it is characterised in that：Active ingredient is that first thiophene lures amine and protective fungicide, and the first thiophene lures amine Weight ratio with protective fungicide is 70：1-1：70.
- 2. bactericidal composition according to claim 1, it is characterised in that：The first thiophene lures the weight of amine and protective fungicide Amount is than being 30：1-1：30.
- 3. bactericidal composition according to claim 1, it is characterised in that：The first thiophene lures the weight of amine and protective fungicide Amount is than being 15：1-1：15.
- 4. according to any described bactericidal compositions of claim 1-3, it is characterised in that：The protective fungicide is Dai Sen Connection, ambam, zineb or Propineb.
- 5. bactericidal composition according to claim 4, it is characterised in that：Also aided in the bactericidal composition containing pesticidal preparations Composition, so that the formulation for being adapted to agriculturally use is made.
- 6. bactericidal composition according to claim 5, it is characterised in that：The pesticidal preparations auxiliary element is solvent, breast One or more in agent, dispersant, stabilizer, antifreezing agent or wetting agent.
- 7. bactericidal composition according to claim 5, it is characterised in that：The formulation of the bactericidal composition is wettable powder Agent, soluble powder, aqua, suspending agent, microemulsion or water dispersible granules.
- 8. the application of any described bactericidal compositions of claim 1-3, it is characterised in that：For preventing and treating plant epiphyte class disease Evil.
- 9. the application of bactericidal composition according to claim 8, it is characterised in that：For prevent and treat black heart, downy mildew, kind Eggplant early blight, rice blast, wheat powdery mildew, sigatoka.
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| CN114982751A (en) * | 2022-07-01 | 2022-09-02 | 河北双吉化工有限公司 | Production process of pesticide water dispersible granules with good stability |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101091490A (en) * | 2007-01-12 | 2007-12-26 | 南开大学 | New type heterocycle bactericide and composition |
| CN102524269A (en) * | 2012-01-17 | 2012-07-04 | 利尔化学股份有限公司 | Bactericidal composition, pesticide and application thereof |
| CN105010358A (en) * | 2014-04-17 | 2015-11-04 | 利尔化学股份有限公司 | Bactericidal composition and application thereof |
| CN105010357A (en) * | 2014-04-23 | 2015-11-04 | 利尔化学股份有限公司 | Sterilization composition and application thereof |
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2016
- 2016-12-12 CN CN201611140988.7A patent/CN107801724A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101091490A (en) * | 2007-01-12 | 2007-12-26 | 南开大学 | New type heterocycle bactericide and composition |
| CN102524269A (en) * | 2012-01-17 | 2012-07-04 | 利尔化学股份有限公司 | Bactericidal composition, pesticide and application thereof |
| CN105010358A (en) * | 2014-04-17 | 2015-11-04 | 利尔化学股份有限公司 | Bactericidal composition and application thereof |
| CN105010357A (en) * | 2014-04-23 | 2015-11-04 | 利尔化学股份有限公司 | Sterilization composition and application thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114982751A (en) * | 2022-07-01 | 2022-09-02 | 河北双吉化工有限公司 | Production process of pesticide water dispersible granules with good stability |
| CN114982751B (en) * | 2022-07-01 | 2023-10-03 | 河北双吉化工有限公司 | Production process of pesticide water dispersible granule with good stability |
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