CN107087609A - Microbicide compositions containing anthraquinone analog compound and S-Ethyl ethylthio sulfonate - Google Patents
Microbicide compositions containing anthraquinone analog compound and S-Ethyl ethylthio sulfonate Download PDFInfo
- Publication number
- CN107087609A CN107087609A CN201710167385.4A CN201710167385A CN107087609A CN 107087609 A CN107087609 A CN 107087609A CN 201710167385 A CN201710167385 A CN 201710167385A CN 107087609 A CN107087609 A CN 107087609A
- Authority
- CN
- China
- Prior art keywords
- ethyl ethylthio
- ethylthio sulfonate
- composition
- emodin
- aloe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
- A01N41/04—Sulfonic acids; Derivatives thereof
- A01N41/08—Sulfonic acid halides; alpha-Hydroxy-sulfonic acids; Amino-sulfonic acids; Thiosulfonic acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/06—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing keto or thioketo groups as part of a ring, e.g. cyclohexanone, quinone; Derivatives thereof, e.g. ketals
Abstract
The invention provides a kind of microbicide compositions, said composition includes two kinds of effective constituents As and B, and active component A is one kind in Physcion and aloe-emodin in anthraquinone analog compound, and active component B is that the weight ratio between S-Ethyl ethylthio sulfonate, two components is 1:1~300, preferably 1:10~250.Present invention also offers the Preparation method and use of said composition.Result of the test shows that the above-mentioned bactericidal composition synergy that the present invention is provided is obvious, it is often more important that amount of application is reduced, use cost reduction.The bactericidal composition can effectively prevent and treat some specific bacteriums or the fungal disease of crop.By the way that the bactericide of different mechanism of action and the mode of action is compounded, there is effect well in terms of germ resistance and raising prevention effect for expanding fungicidal spectrum and delaying.
Description
Technical field
It is more particularly to a kind of that there is the bactericidal composition for improving performance, tool the invention belongs to agriculture plant protection field
Say it is to be related to a kind of bactericidal composition comprising anthraquinone analog compound and S-Ethyl ethylthio sulfonate body.
Background technology
Physcion, aloe-emodin etc. belong to anthraquinone analog compound.In field of medicaments, these compounds are extensive
Using such as immunoregulation is acted on, scavenging activated oxygen effect, antibacterial, anti-inflammatory, antivirus action, diuresis, to cerebrum ischemia
The protective effect of damage, cardiovascu- lar effects, antitumor action.In recent years, these anthraquinone analog compounds are just progressively employed
In agriculture field, particularly Physcion and aloe-emodin, it be used to preventing and treating fungoid, bacillary or Disease,
It is notable to veterinary antibiotics, the powdery mildew of cereal, downy mildew, gray mold, anthracnose, eye spot disease preventive effect, while to people and animals' low toxicity,
Environmentally friendly, with other chemical agent no interactions resistances, with preferable uptake and translocation effect, lasting effect is strong.It, which is sterilized, makees
It is the biosynthesis by disturbing disease fungus cell membrane chitin with mechanism, suppresses sprouting, the life of mycelia of pathogen spore
The long, formation of haustorium, so as to block spreading for disease, also can induce crop and produces degeneration-resistant defense reaction, reach the effect of diseases prevention.
S-Ethyl ethylthio sulfonate (Ethylicin) is a kind of environment friendly agricultural with plant bionic structure of China's independent development, is belonged to
Efficiently, low toxicity, low-residual broad-spectrum germicide, during the mechanism of action is its molecular structureContain in group and phage molecule-
The substance reaction of SH bases, so as to suppress the eubolism of thalline.Current S-Ethyl ethylthio sulfonate is widely used in preventing and treating cotton wilt, Huang and withered
Disease, damping-off, anthracnose, rice blast, banded sclerotial blight, bacterial leaf-blight, bakanae disease, seedling rot, wheat class stripe disease, head blight,
Smut, fruit tree leaf spot, ring spot, anthracnose, gourd, fruit and vegetable downy mildew, bacterial wilt, anthracnose, droop, epidemic disease, angle spot
The multiple diseases such as disease.Relevant report shows that S-Ethyl ethylthio sulfonate is compounded with other bactericide such as triazole bactericidal agent, and protection effect can be improved
40%~75%, at present, the bactericide of S-Ethyl ethylthio sulfonate compounding is got the attention and applications well.
Actual agricultural chemicals experience have shown that, repeat and single-minded apply a kind of reactive compound to prevent and treat harmful fungoid very
It will cause the fast selective of fungal bacterial strain in the case of many, it is current usual for the danger of reduction refractory fungal bacterial strain selectivity
Harmful fungoid is prevented and treated using the mixture of different activities compound.By the way that the reactive compound with the different mechanisms of action is entered
Row combination, can delaying drug resistance generation, reduction amount of application, reduction cost accounting.
The content of the invention
The purpose of the present invention is to be directed to bactericide resistance and pedo relict problem in actual applications, filters out difference and kills
The bactericide of bacterium principle is compounded, and obtains a kind of new microbicide compositions, to improve bactericidal agent for preventing and treating effect, delaying drug resistance
Produce, reduce amount of application, reduce cost accounting.
It is a further object to provide the preparation method comprising two kinds of effective constituents As and B bactericidal compositions and
Application in agriculture field preventing and treating corps diseases.
The purpose of the present invention can be reached by following measures：
A kind of microbicide compositions with synergistic effect, said composition includes two kinds of active components of A and B, active component A
For anthraquinone analog compound, active component B is that the weight ratio between S-Ethyl ethylthio sulfonate, two components is 1:1~300, wherein, Anthraquinones chemical combination
The one kind of thing in Physcion and aloe-emodin.
Inventor is found by experiment that composition of the invention is to be used to prevent and treat bacillary crops, fungoid or virus
Venereal disease is done harm to, and preventing and treating synergy is obvious, it is often more important that amount of application is reduced, and reduces use cost.Component A and component B compound knot
Structure type is different, and mechanism of action is different, and both can expand fungicidal spectrum at compounding, and can delay pathogen to a certain extent
No interactions resistance between the generation of resistance and development speed, and component A and component B.
Weight ratio between two components in microbicide compositions of the present invention is 1:10~300.To make the medicine between two components
Effect synergistic effect is more notable, and the weight ratio between component A and component the B component of weight two can further be optimized to 1：10~
250。
In a kind of preferred scheme, the weight ratio between A and the components of B two arbitrarily can enter in the range of following proportionings
Row adjustment：1：1、1：2、1：3、1：4、1：5、1：6、1：7、1：8、1：9、1：10、1：11、1：12、1：13、1：14、1：15、1：
16、1：17、1：18、1：19、1：20、1：21、1：22、1：23、1：24、1：25、1：26、1：27、1：28、1：29、1：30,1:
32、1:33、1:34、1:35、1:36、1:37、1:38、1:39、1:40、1:41、1:42、1:43、1:44、1:45、1:46、1:
47、1:48、1:49、1:50、1:51、1:52、1:53、1:54、1:55、1:56、1:57、1:58、159:、1:60、1:61、1:
62、1:63、1:64、1:65、1:66、1:67、1:68、1:69、1:70、1:71、1:72、1:73、1:74、1:75、1:76、1:
77、1:78、1:79、1:80、1:81、1:82、1:83、1:84、1:85、1:86、1:87、1:88、1:89、1:90、1:91、1:
92、1:93、1:94、1:95、1:96、1:97、1:98、1:99、1:100、1:110、1:120、1:130、1:140、1:150、1:
160、1:170、1:180、1:190、1:200、1:210、1:220、1:230、1:240、1:250、1:260、1:270、1:280、
1:290、1:300, it can also carry out selecting these ratios can be understood as in the range of two proportionings of any of the above are constituted
Weight ratio, can also include mol ratio.
The formulation allowed on agricultural chemicals can be made by active component and insecticides adjuvant or auxiliary material in the composition of the present invention.Enter one
Step, said composition constitutes agriculture by the active component of 2~90% parts by weight and the insecticides adjuvant of 98~10% parts by weight or auxiliary material
The formulation allowed on medicine.
The invention provides the bactericidal composition comprising component A and component B in terms of agriculture field preventing and treating corps diseases
Purposes, the particularly purposes in terms of the fungi of some crops or bacterial disease is prevented and treated.
Above-mentioned composition can specifically include insecticides adjuvant or auxiliary material, for example carrier, solvent, dispersant, wetting agent, gluing
One or more in agent, thickener, adhesive, surfactant and fertilizer etc..It can be mixed during administration conventional
Auxiliary agent.
Suitable auxiliary agent or auxiliary material can be solid or liquid, and they are typically the material commonly used during formulation,
For example natural or regeneration mineral matter, solvent, dispersant, wetting agent, adhesive, thickener, adhesive.
The application process of the present composition includes being used for the composition of the present invention into the aerial part of plant growth, especially
It is leaf portion or blade face.It can select to soak seed or be applied to controlling object surface.The frequency and amount of application of administration depend on pathogen
Biology and weather life condition.The growth place of plant, such as rice field can be soaked with the liquid preparation of composition, or
Composition is applied in soil by person in solid form, such as in granular form (soil application), and composition can be by soil through planting
Thing root enters in plant (systemic action).
The composition of the present invention can be prepared into acceptable various formulations on agricultural chemicals, including but not limited to missible oil, suspension
Agent, wettable powder, water dispersible granules, pulvis, granula, aqua, aqueous emulsion, microemulsion, encapsulated form, mother liquor, female powder etc.,
In a kind of preferred scheme, formulation of the invention uses wettable powder, suspending agent, water dispersible granules, aqueous emulsion or microemulsion.Root
The purpose and ambient conditions to be reached according to the property of these compositions and using composition, can select composition to spray
Mist, atomizing, dust, broadcast sowing or sprinkle the method poured or the like and apply.
The composition of the present invention can be prepared into various formulations with known method, can be by active ingredient with helping
Agent, such as solvent, solid carrier, it is necessary to when can uniformly mix, grind together with surfactant, be prepared into required agent
Type.
Above-mentioned solvent may be selected from aromatic hydrocarbon, preferably containing 8-12 carbon atom, such as xylene mixture or substituted benzene, phthalein
The octanoic acid of esters of gallic acid, such as Dibutyl phthalate or phthalandione two, such as fat hydrocarbon, thiacyclohexane or paraffin, alcohol and ethylene glycol and their ether
And ester, such as ethanol, ethylene glycol, ethylene glycol monomethyl；Ketone, such as cyclohexanone, such as highly polar solvent, N- methyl -2- pyrrolidines
Ketone, dimethyl sulfoxide (DMSO) or dimethylformamide, and vegetable oil or vegetable oil, such as soybean oil.
Above-mentioned solid carrier, is such as used for the typically natural mineral fillers, such as talcum, kaolinite of pulvis and dispersible dose
Soil, montmorillonite or atlapulgite.In order to manage the physical property of composition, polymolecularity silicic acid or polymolecularity can also be added
Adsorpting polymerization thing carrier, such as granulated adsorptive carriers or non-adsorbed carrier, suitable granulated adsorptive carriers are porous types, such as floating
Stone, bentonite or bentonite；Suitable non-adsorbed carrier such as calcite or sand.Further, it is possible to use substantial amounts of inorganic in nature or having
The prefabricated material granulated of machine property is used as carrier, particularly dolomite.
The chemical property of active ingredient in the composition of the present invention, suitable surfactant is sulfomethylated lignin
Acid, naphthalene sulfonic acids, phenolsulfonic acid, alkali salt or amine salt, alkylaryl sulfonates, alkyl sulfate, alkylsulfonate, fat
The condensation product of alcohol sulfate, aliphatic acid and sulphated fatty alcohol glycol ether, also sulfonated naphthalene and naphthalene derivatives and formaldehyde, naphthalene or
Naphthalene sulfonic acids and phenol and the condensation product of formaldehyde, NONIN HS 240, ethoxylated isooctyl-phenol, octyl phenol, nonyl phenol,
Alkylaryl polyglycol ether, tributyl benzene polyglycol ether, three stearyl phenyl polyglycol ethers, alkyl aryl polyether alcohol,
Ethoxylated castor oil, polyoxyethylene alkyl ether, ethylene oxide condensation product, ethoxylation polyoxypropylene, bay acid polyethylene glycol
Ether acetal, sorbitol ester, lignin sulfite waste liquor and methylcellulose.
Two kinds of active ingredients show as synergistic effect in the composition of the present invention, and the activity of said composition is than using individualized
The expected summation of activity of compound, and the independent activity of single compound are more notable.Synergistic effect shows as allowing amount of application
Reduce, broader antifungal control spectrum, instant effect, more longlasting prevention effect, by only once or a small number of several times using more
Good control plant pest fungi and broaden the possible administration interval time.These characteristics are plant epiphyte control practices
During especially need.
In terms of the microbicide compositions of the present invention can be applied to agriculture field preventing and treating corps diseases, farming referred herein
Thing disease particularly Fusarium and Verticillium wilts, damping-off, anthracnose, rice blast, banded sclerotial blight, bacterial leaf-blight, evil seedling
Disease, seedling rot, powdery mildew of cereals, stripe disease, head blight, smut, fruit tree leaf spot, ring spot, anthracnose, gourd, fruit and vegetable are white
Powder disease, downy mildew, gray mold, bacterial wilt, anthracnose, droop, epidemic disease, angular leaf spot, oilseed rape downy mildew etc..But the present invention
Composition is in addition to it can prevent and treat foregoing disease, moreover it is possible to which the specific illness of preventing and treating includes but is not limited to rice disease (such as：Paddy rice bacterium
Property streak etc.), maize diseases (such as：Smut of maize, the leaf blight of corn, corn southern leaf blight), citrus disease (such as：Citrus scab
Disease), tobacco diseases (such as：Wildfire, Alternaria alternate etc.), rape disease (such as：Sclerotinia sclerotiorum), potato class disease it is (sweet
Potato black spot, sweet potato root rot, dry rot of potato, potato scab, Chinese yam spot stripe, Chinese yam anthracnose etc.), soybean disease
Evil (purple spot of soybean, downy mildew, root rot etc.).
Other features for showing of bactericidal composition of the present invention are mainly：1st, composition mixture of the invention has obvious
Synergistic effect；2nd, because two single dose chemical constitutions of this composition are widely different, the mechanism of action is entirely different, in the absence of friendship
Mutual resistance, can delay two single doses that produced resistance problem is used alone；3rd, composition of the invention is to crop safety, preventive effect
It is good.Tests prove that, microbicide compositions chemical property of the present invention is stable, and synergy significantly, is shown significantly to controlling object
Synergy and complementation.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that specific embodiment described herein is not used to limit only to explain the present invention
The fixed present invention, any modifications, equivalent replacements and improvementsmade within the spirit and principles of the invention, should be included in
Within protection scope of the present invention.
Percentage is weight percentage in all formulas of following examples.The processing work of the various preparations of the present composition
Skill is prior art, can be varied from according to different situations.
First, formulation prepares embodiment
(1) processing of suspending agent and embodiment
By active component active component A and active component B, with each component such as dispersant, wetting agent, thickener and water by matching somebody with somebody
The ratio of side is well mixed, and after sand milling and/or high speed shear, obtains semi-finished product, is mended after analysis and is mixed with water filtering i.e.
Obtain finished product.
(1) active component A (Physcion) prepares suspending agent with S-Ethyl ethylthio sulfonate
Embodiment 1：60.2% Physcion S-Ethyl ethylthio sulfonate suspending agent
Physcion 0.2%, S-Ethyl ethylthio sulfonate 60%, methyl naphthalene sulfonate formaldehyde condensate 8%, xanthans 5%, dimethylbenzene
6%, ammonium sulfate 5%, water complements to 100%.
Embodiment 2：25.5% Physcion S-Ethyl ethylthio sulfonate suspending agent
Physcion 0.5%, S-Ethyl ethylthio sulfonate 25%, remaining component is prepared according to the method for embodiment 1.
(2) active component A (aloe-emodin) prepares suspending agent with S-Ethyl ethylthio sulfonate
Embodiment 3：60.2% aloe-emodin S-Ethyl ethylthio sulfonate suspending agent
Aloe-emodin 0.2%, S-Ethyl ethylthio sulfonate 60%, remaining component is prepared according to the method for embodiment 1.
Embodiment 4：25.5% aloe-emodin S-Ethyl ethylthio sulfonate suspending agent
Aloe-emodin 0.5%, S-Ethyl ethylthio sulfonate 25%, remaining component is prepared according to the method for embodiment 1.
(2) processing of missible oil and embodiment
By active component activity packet A and active component B, mixed with each component such as solvent, emulsifying agent by the ratio being formulated,
It is agitated it is uniform after, obtain single-phase transparent liquid, add that solvent is well mixed to produce missible oil after analysis.
(1) active component A (Physcion) prepares missible oil with S-Ethyl ethylthio sulfonate
Embodiment 5：50.5% Physcion S-Ethyl ethylthio sulfonate missible oil
Physcion 0.5%, S-Ethyl ethylthio sulfonate 50%, calcium dodecyl benzene sulfonate 15%, dimethylbenzene complements to 100%.
Embodiment 6：22% Physcion S-Ethyl ethylthio sulfonate missible oil
Physcion 2%, S-Ethyl ethylthio sulfonate 20%, remaining component is prepared according to the method for embodiment 5.
(2) active component A (aloe-emodin) prepares missible oil with S-Ethyl ethylthio sulfonate
Embodiment 7：50.5% aloe-emodin S-Ethyl ethylthio sulfonate missible oil
Aloe-emodin 0.5%, S-Ethyl ethylthio sulfonate 50%, remaining component is prepared according to the method for embodiment 5.
Embodiment 8：22% aloe-emodin S-Ethyl ethylthio sulfonate missible oil
Aloe-emodin 2%, S-Ethyl ethylthio sulfonate 20%, remaining component is prepared according to the method for embodiment 5.
(3) processing of wettable powder and embodiment
Active components A and B activity composition and various auxiliary agents and filler etc. are sufficiently mixed in proportion, through ultrafine crusher powder
Obtained wettable powder after broken.
(1) active component A (Physcion) prepares wettable powder with S-Ethyl ethylthio sulfonate
Embodiment 9：20% Physcion S-Ethyl ethylthio sulfonate wettable powder
Physcion 10%, S-Ethyl ethylthio sulfonate 10%, lignosulfonates 6%, alkylsulfonate 6%, xanthans 5% is swollen
Profit soil 8%, precipitated calcium carbonate complements to 100%.
Embodiment 10：45.3% Physcion S-Ethyl ethylthio sulfonate wettable powder
Physcion 0.3%, S-Ethyl ethylthio sulfonate 45%, remaining component is prepared according to the method for embodiment 9.
(2) active component A (aloe-emodin) prepares wettable powder with S-Ethyl ethylthio sulfonate
Embodiment 11：20% aloe-emodin S-Ethyl ethylthio sulfonate wettable powder
Aloe-emodin 10%, S-Ethyl ethylthio sulfonate 10%, remaining component is prepared according to the method for embodiment 9.
Embodiment 12：45.3% aloe-emodin S-Ethyl ethylthio sulfonate wettable powder
Aloe-emodin 0.3%, S-Ethyl ethylthio sulfonate 45%, remaining component is prepared according to the method for embodiment 9.
(4) processing of microemulsion and embodiment
By active components A and S-Ethyl ethylthio sulfonate, it is well mixed with solvent, surfactant, stabilizer, water in the ratio of formula,
Microemulsion product is made afterwards.
(1) active component A (Physcion) prepares microemulsion with S-Ethyl ethylthio sulfonate
Embodiment 13：50.2% Physcion S-Ethyl ethylthio sulfonate microemulsion
Physcion 0.2%, S-Ethyl ethylthio sulfonate 50%, dimethyl sulfoxide (DMSO) 15%, the condensation of diphenyl phenol polyethenoxy polyformaldehyde
Thing 8%, magnesium stearate 6%, water complements to 100%.
Embodiment 14：40.2% Physcion S-Ethyl ethylthio sulfonate microemulsion
Physcion 0.2%, S-Ethyl ethylthio sulfonate 40%, remaining component is prepared according to the method for embodiment 13.
(2) active component A (aloe-emodin) prepares microemulsion with S-Ethyl ethylthio sulfonate
Embodiment 15：50.2% aloe-emodin S-Ethyl ethylthio sulfonate microemulsion
Aloe-emodin 0.2%, S-Ethyl ethylthio sulfonate 50%, remaining component is prepared according to the method for embodiment 13.
Embodiment 16：40.2% aloe-emodin S-Ethyl ethylthio sulfonate microemulsion
Aloe-emodin 0.2%, S-Ethyl ethylthio sulfonate 40%, remaining component is prepared according to the method for embodiment 13.
2nd, drug effect checking test
(1) Assays Example
The incidence of whole strain blade is investigated according to experiment grade scale, disease index and prevention effect is calculated.
Prevention effect is converted into niqueMin (y), liquor strength (μ g/ml) is converted into logarithm value (x), with least square method
Concentration EC50 in calculating virulence equation and suppressing, the toxicity index and co-toxicity coefficient (CTC) of medicament are calculated according to the abundant methods of Sun Yun.
Survey toxicity index (ATI)=(standard agent EC50/ reagent agent EC50) * 100
A percentage composition+B medicament toxicity index * mixtures in theoretical toxicity index (TTI)=A medicament toxicity index * mixtures
Middle B percentage composition
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (ATI)/mixture theoretical toxicity index (TTI)] * 100
CTC≤80, composition shows as antagonism, 80 ＜ CTC ＜ 120, and composition shows as summation action, and CTC >=
120, composition shows as synergistic effect.
1st, Physcion and S-Ethyl ethylthio sulfonate compounding are tested rape powdery mildew toxicity test
The Physcion of table 1. is compounded to rape powdery mildew toxicity test interpretation of result with S-Ethyl ethylthio sulfonate
As a result (table 1) shows, in Physcion：S-Ethyl ethylthio sulfonate=1:In 1~300 interval range, Physcion and second
Allicin is compounded to be significantly improved to the prevention effect of rape powdery mildew, illustrates that the two compounding has significant increasing to rape controlling powdery mildew
Effect is acted on.And Physcion：S-Ethyl ethylthio sulfonate=1:Outside 1~300 interval range, both then show the effect of addition.
2nd, aloe-emodin and S-Ethyl ethylthio sulfonate compounding are tested root rot toxicity test
The aloe-emodin of table 2. is compounded to root rot toxicity test interpretation of result with S-Ethyl ethylthio sulfonate
| Medicament title | EC50(ug/mL) | ATI | TTI | CTC |
| Aloe-emodin | 3.78 | 100.00 | \ | \ |
| S-Ethyl ethylthio sulfonate | 76.25 | 4.96 | \ | \ |
| Aloe-emodin：S-Ethyl ethylthio sulfonate=1:350 | 64.30 | 5.88 | 5.23 | 112.38 |
| Aloe-emodin：S-Ethyl ethylthio sulfonate=1:300 | 56.88 | 6.65 | 5.28 | 125.97 |
| Aloe-emodin：S-Ethyl ethylthio sulfonate=1:250 | 52.55 | 7.19 | 5.34 | 134.75 |
| Aloe-emodin：S-Ethyl ethylthio sulfonate=1:200 | 47.36 | 7.98 | 5.43 | 146.92 |
| Aloe-emodin：S-Ethyl ethylthio sulfonate=1:150 | 43.12 | 8.77 | 5.59 | 156.85 |
| Aloe-emodin：S-Ethyl ethylthio sulfonate=1:100 | 43.39 | 8.71 | 5.90 | 147.63 |
| Aloe-emodin：S-Ethyl ethylthio sulfonate=1:50 | 39.98 | 9.46 | 6.82 | 138.57 |
| Aloe-emodin：S-Ethyl ethylthio sulfonate=1:10 | 20.70 | 18.26 | 13.60 | 134.28 |
| Aloe-emodin：S-Ethyl ethylthio sulfonate=1:1 | 5.71 | 66.19 | 52.48 | 126.12 |
| Aloe-emodin：S-Ethyl ethylthio sulfonate=1:0.1 | 3.55 | 106.33 | 91.36 | 116.39 |
As a result (table 2) shows, in aloe-emodin：S-Ethyl ethylthio sulfonate=1:In 1~300 interval range, aloe-emodin and second
Allicin is compounded to be significantly improved to the prevention effect of root rot, illustrates that the two compounding has significant increasing to root rot preventing and treating
Effect is acted on.And aloe-emodin：S-Ethyl ethylthio sulfonate=1:Outside 1~300 interval range, both then show the effect of addition.
(2) field efficacy checking test
Test method：At the initial stage of a disease, first time spraying is carried out immediately, and second of dispenser is carried out after 7 days, 4 are each handled
Individual cell, each square meter of cell 20.In 11 days investigation statisticses incidences before medicine and after second medicine, each 5 points of cell is random
Sampling, 5 plants of crops of every investigation, investigates percentage and classification that the lesion area in whole strain per blade accounts for blade area, calculates
Disease index and prevention effect.
It is expected that preventive effect (%)=X+Y-XY/100 (wherein, X, Y are single dose preventive effect)
Grade scale：
0 grade：Disease-free spot；
1 grade：Leaf spot lesion is less than 5, and length is less than 1cm；
3 grades：Leaf spot lesion 6-10, part scab length is more than 1cm；
5 grades：Leaf spot lesion 11-25, part scab is linked to be piece, and lesion area accounts for the 10-25% of leaf area；
7 grades：Leaf spot lesion more than 26, scab is linked to be piece, and lesion area accounts for the 26-50% of leaf area；
9 grades：Scab is linked to be piece, and more than 50% or the full leaf that lesion area accounts for leaf area are withered.
1st, Physcion and S-Ethyl ethylthio sulfonate compounding field efficacy experiment
The Physcion of table 3 is with S-Ethyl ethylthio sulfonate mixture to Chinese yam spot stripe prevention effect
Measurement result (table 3) shows that Physcion is significantly improved with S-Ethyl ethylthio sulfonate mixture to the preventive effect of Chinese yam spot stripe, is said
The two bright compounding has significant synergistic effect to Chinese yam spot stripe.
2nd, aloe-emodin and S-Ethyl ethylthio sulfonate compounding field efficacy experiment
The aloe-emodin of table 4 is with S-Ethyl ethylthio sulfonate mixture to wildfire prevention effect
Measurement result (table 4) shows that aloe-emodin is significantly improved with S-Ethyl ethylthio sulfonate mixture to the preventive effect of wildfire, is said
The two bright compounding has significant synergistic effect to wildfire.
Claims (8)
1. a kind of microbicide compositions, it is characterised in that described composition includes two kinds of active components of A and B, active component A is
Anthraquinone analog compound, active component B is that the weight ratio between S-Ethyl ethylthio sulfonate, two components is 1:1~300, wherein, anthraquinone analog compound
One kind in Physcion and aloe-emodin.
2. microbicide compositions according to claim 1, it is characterised in that active component A and active component B weight ratio
For 1:10~300.
3. microbicide compositions according to claim 1, it is characterised in that Physcion or aloe-emodin and second garlic
The weight ratio of element is 1:10~250.
4. the microbicide compositions according to any one in claims 1 to 3, it is characterised in that said composition by activity into
Divide and the formulation allowed on agricultural chemicals is made with insecticides adjuvant or auxiliary material.
5. microbicide compositions according to claim 4, it is characterised in that said composition by 2~90% parts by weight activity
Component and the formulation allowed on insecticides adjuvant or auxiliary material the composition agricultural chemicals of 98~10% parts by weight.
6. the microbicide compositions according to claim 4 or 5, it is characterised in that described formulation be suspending agent, missible oil, can
WP, microemulsion.
7. the microbicide compositions according to claim 4,5 or 6, it is characterised in that the insecticides adjuvant or auxiliary material, which are selected from, to be carried
One or more in body, solvent, dispersant, wetting agent, adhesive, thickener, adhesive, surfactant and fertilizer.
8. the microbicide compositions in claim 1~7 described in any one are in terms of agriculture field preventing and treating corps diseases
Purposes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710167385.4A CN107087609A (en) | 2017-03-21 | 2017-03-21 | Microbicide compositions containing anthraquinone analog compound and S-Ethyl ethylthio sulfonate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710167385.4A CN107087609A (en) | 2017-03-21 | 2017-03-21 | Microbicide compositions containing anthraquinone analog compound and S-Ethyl ethylthio sulfonate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107087609A true CN107087609A (en) | 2017-08-25 |
Family
ID=59648882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710167385.4A Withdrawn CN107087609A (en) | 2017-03-21 | 2017-03-21 | Microbicide compositions containing anthraquinone analog compound and S-Ethyl ethylthio sulfonate |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107087609A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109938045A (en) * | 2019-02-27 | 2019-06-28 | 江苏辉丰生物农业股份有限公司 | Composition pesticide containing toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Physcion |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1515152A (en) * | 2003-08-29 | 2004-07-28 | 湖北省农业科学植保土肥研究所 | Application of antraquinone derivative as pesticide for controlling plant diseases |
| CN1860875A (en) * | 2005-05-12 | 2006-11-15 | 青岛科技大学 | Microemulsion of S-Ethyl ethylthio sulfonate and its prepn. method |
| CN102674981A (en) * | 2012-06-11 | 2012-09-19 | 内蒙古永业农丰生物科技有限责任公司 | Preparation and application of compound chemical fertilizer capable of promoting growth and health of plants |
| CN104145961A (en) * | 2014-08-13 | 2014-11-19 | 海南正业中农高科股份有限公司 | Composition comprising ethylicin and dithianon |
| CN104642312A (en) * | 2015-02-13 | 2015-05-27 | 兰州大学 | Rheum officinale free anthraquinone composition for preventing plant powdery mildew and nano emulsion preparation |
-
2017
- 2017-03-21 CN CN201710167385.4A patent/CN107087609A/en not_active Withdrawn
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1515152A (en) * | 2003-08-29 | 2004-07-28 | 湖北省农业科学植保土肥研究所 | Application of antraquinone derivative as pesticide for controlling plant diseases |
| CN1860875A (en) * | 2005-05-12 | 2006-11-15 | 青岛科技大学 | Microemulsion of S-Ethyl ethylthio sulfonate and its prepn. method |
| CN102674981A (en) * | 2012-06-11 | 2012-09-19 | 内蒙古永业农丰生物科技有限责任公司 | Preparation and application of compound chemical fertilizer capable of promoting growth and health of plants |
| CN104145961A (en) * | 2014-08-13 | 2014-11-19 | 海南正业中农高科股份有限公司 | Composition comprising ethylicin and dithianon |
| CN104642312A (en) * | 2015-02-13 | 2015-05-27 | 兰州大学 | Rheum officinale free anthraquinone composition for preventing plant powdery mildew and nano emulsion preparation |
Non-Patent Citations (1)
| Title |
|---|
| 王雪等: "三十七种生物农药对西瓜细菌性果斑病菌的室内抑菌效果测定", 《北方园艺》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109938045A (en) * | 2019-02-27 | 2019-06-28 | 江苏辉丰生物农业股份有限公司 | Composition pesticide containing toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Physcion |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105494387B (en) | A kind of composition pesticide | |
| CN101690480B (en) | Pesticide composition containing methoxy acrylic bactericide and application thereof | |
| CN101690483B (en) | Bactericidal composition containing triazole class compounds | |
| CN102763657A (en) | Germicide composite with synergistic effect | |
| CN106942240B (en) | A kind of microbicide compositions comprising emodin derivates and benzoisothiazolinone | |
| CN108338173A (en) | A kind of bactericidal composition including benzoisothiazolinone class and fluorine thiazole pyrrole ethyl ketone | |
| CN102630679A (en) | Pesticide composition containing orysastrobin | |
| CN106719646A (en) | A kind of microbicide compositions comprising anthraquinone analog compound and methoxy acrylic | |
| CN109315400A (en) | A kind of microbicide compositions | |
| CN106259366B (en) | A kind of microbicide compositions | |
| CN106561720B (en) | The bactericidal composition of class containing benzoisothiazolinone and toVerticilliumdahliaActivitie Activitie S of Relative activator protein | |
| CN106857511A (en) | A kind of microbicide compositions comprising emodin derivates Yu pyrazol acid amide compounds | |
| CN106818783A (en) | A kind of microbicide compositions comprising BIT class and tetraconazole | |
| CN106234392B (en) | A kind of microbicide compositions | |
| CN106212480B (en) | A kind of microbicide compositions | |
| CN109845736A (en) | Bactericidal composition containing toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Physcion | |
| CN104756993B (en) | Bactericidal composition containing metconazole | |
| CN108338165A (en) | A kind of microbicide compositions including emodin derivates and polysaccharide | |
| CN106172437B (en) | A kind of microbicide compositions | |
| CN106070245B (en) | A kind of microbicide compositions | |
| CN107087609A (en) | Microbicide compositions containing anthraquinone analog compound and S-Ethyl ethylthio sulfonate | |
| CN107372528A (en) | A kind of bactericidal composition and its application containing prothioconazoles and S-Ethyl ethylthio sulfonate | |
| CN106376578B (en) | A kind of microbicide compositions | |
| CN107232213A (en) | Microbicide compositions containing anthraquinone analog compound and polyoxin | |
| CN109526958A (en) | Microbicide compositions containing rheum emodin and metconazole |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170825 |