CN107232213A - Microbicide compositions containing anthraquinone analog compound and polyoxin - Google Patents
Microbicide compositions containing anthraquinone analog compound and polyoxin Download PDFInfo
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- CN107232213A CN107232213A CN201710445699.6A CN201710445699A CN107232213A CN 107232213 A CN107232213 A CN 107232213A CN 201710445699 A CN201710445699 A CN 201710445699A CN 107232213 A CN107232213 A CN 107232213A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/06—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing keto or thioketo groups as part of a ring, e.g. cyclohexanone, quinone; Derivatives thereof, e.g. ketals
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Abstract
The invention provides a kind of microbicide compositions, said composition includes two kinds of effective constituents As and B, active component A is one kind in Physcion, aloe-emodin in anthraquinone analog compound, and active component B is that the weight ratio between polyoxin, two components is 10~1:2~100.Present invention also offers the Preparation method and use of said composition.Result of the test shows that the above-mentioned bactericidal composition synergy that the present invention is provided is obvious, it is often more important that amount of application is reduced, use cost reduction.The bactericidal composition can effectively prevent and treat some specific bacteriums or the fungal disease of crop.By the way that the bactericide of different mechanism of action and the mode of action is compounded, there is effect well in terms of germ resistance and raising prevention effect for expanding fungicidal spectrum and delaying.
Description
Technical field
It is more particularly to a kind of that there is the bactericidal composition for improving performance, tool the invention belongs to agriculture plant protection field
Say it is to be related to a kind of bactericidal composition comprising anthraquinone analog compound and polyoxin body.
Background technology
Physcion and aloe-emodin belong to anthraquinone analog compound.Extensively should in these compounds of field of medicaments
With such as immunoregulation effect, scavenging activated oxygen effect, antibacterial, anti-inflammatory, antivirus action, diuresis is damaged to cerebrum ischemia
The protective effect of wound, cardiovascu- lar effects, antitumor action.In recent years, these anthraquinone analog compounds are just progressively applied to
Agriculture field, for preventing and treating fungi or bacterial disease.
Physcion and aloe-emodin are the class highly active vegetables extracted from the root, stem of Chinese herbal medicine rheum officinale
The multiple diseases such as the powdery mildew of veterinary antibiotics, cereal etc., downy mildew, gray mold, anthracnose are had well by source bactericide
Prevention effect, at the same to people and animals' low toxicity, it is environmentally friendly, with other chemical agent no interactions resistances, passed with preferably interior inhale
Effect is led, lasting effect is strong.Its bactericidal action mechanism is the biosynthesis by disturbing disease fungus cell membrane chitin, suppresses disease
The sprouting of opportunistic pathogen spore, the growth of mycelia, the formation of haustorium, so as to block spreading for disease, also can induce crop generation degeneration-resistant
Defense reaction, reaches the effect of diseases prevention.
Polyoxin (polyoxin) is the metabolite produced by streptomyces aureus, belongs to the sterilization of broad-spectrum antibiotics class
Agent.With preferable uptake and translocation effect.Its mechanism of action is to disturb the biosynthesis of germ cell membrane chitin, makes thalline thin
Cell wall, which can not carry out biosynthesis, causes germ dead.After germ tube and mycelia contact medicament, local bulkiness, rupture, spilling cell
Inclusion, and normal development is unable to, cause death.Therefore also have and suppress the effect that germ production spore and scab expand.
Actual agricultural chemicals experience have shown that, repeat and single-minded apply a kind of reactive compound to prevent and treat harmful fungoid very
It will cause the fast selective of fungal bacterial strain in the case of many, it is current usual for the danger of reduction refractory fungal bacterial strain selectivity
Harmful fungoid is prevented and treated using the mixture of different activities compound.By the way that the reactive compound with the different mechanisms of action is entered
Row combination, can delaying drug resistance generation, reduction amount of application, reduction cost accounting.
The content of the invention
The purpose of the present invention is to be directed to bactericide resistance and pedo relict problem in actual applications, filters out difference and kills
The bactericide of bacterium principle is compounded, and obtains a kind of new microbicide compositions, to improve bactericidal agent for preventing and treating effect, delaying drug resistance
Produce, reduce amount of application, reduce cost accounting.
It is a further object to provide prevented and treated comprising two kinds of effective constituents As and B bactericidal compositions in agriculture field
The application of corps diseases.
The purpose of the present invention can be reached by following measures：
A kind of microbicide compositions with synergistic effect, said composition includes two kinds of active components of A and B, wherein activity
Component A is anthraquinone analog compound, and active component B is polyoxin, and active component A and active component B weight ratio are 1:0.2~
100, wherein, the one kind of anthraquinone analog compound in Physcion or aloe-emodin.
Inventor is found by experiment that composition of the invention is to be used to prevent and treat crops bacterium or fungal disease, is prevented
Control synergy obvious, it is often more important that amount of application is reduced, reduce use cost.Compound structure type containing component A Yu component B
Difference, mechanism of action is different, and both can expand fungicidal spectrum at compounding, and can delay pathogen resistance to a certain extent
Produce the no interactions resistance between development speed, and component A and component B.
The weight between two components in microbicide compositions of the present invention is than the weight for active component A and active component B
Than 1:0.2~100.In a kind of preferred scheme, active component A and active component B weight ratio are 1:1~70, to make two groups
Drug effect synergistic effect between point is more notable, and both weight ratios can further preferred 1：1~50.
In a kind of preferred scheme, the weight ratio between A and the components of B two can be arbitrarily in the range of following proportionings
It is adjusted 10:1、9:2、8:1、7:2、6:1、5:2、4:1、3:2、2:1、1:1、1:2、1:3、1:4、1:5、1:6、1:7、1:8、
1:9、1:10、1:11、1:12、1:13、1:14、1:15、1:16、1:17、1:18、1:19、1:20、1:21、1:22、1:23、1:
24、1:25、1:26、1:27、1:28、1:29、1:30、1:31、1:32、1:33、1:34、1:35、1:36、1:37、1:38、1:
39、1:40、1:41、1:42、1:43、1:44、1:45、1:46、1:47、1:48、1:49、1:50、1:51、1:52、1:53、1:
54、1:55、1:56、1:57、1:58、1:59、1:60、1:61、1:62、1:63、1:64、1:65、1:66、1:67、1:68、1:
69、1:70,1:71、1:72、1:73、1:74、1:75、1:76、1:77、1:78、1:79、1:80、1:81、1:82、1:83、1:
84、1:85、1:86、1:87、1:88、1:89、1:90、1:91、1:92、1:93、1:94、1:95、1:96、1:97、1:98、1:
99、1:100, it can also be selected in the range of two proportionings of any of the above are constituted, these ratios can be understood as matter
Amount ratio, or both weight and volume ratio, mol ratio can also be included.
The formulation allowed on agricultural chemicals can be made by active component and insecticides adjuvant or auxiliary material in the composition of the present invention.Enter one
Step, agriculture is made by the active component of 2~85% parts by weight and the insecticides adjuvant of 98~15% parts by weight or auxiliary material in said composition
The formulation allowed on medicine.
The invention provides the bactericidal composition comprising component A and component B in terms of agriculture field preventing and treating corps diseases
Purposes, the particularly use in terms of the fungi of some crops (for example, veterinary antibiotics and cereal) or bacterial disease is prevented and treated
On the way.
Above-mentioned composition can specifically include insecticides adjuvant or auxiliary material, for example carrier, solvent, dispersant, wetting agent, gluing
One or more in agent, thickener, adhesive, surfactant and fertilizer etc..It can be mixed during administration conventional
Auxiliary agent.
Suitable auxiliary agent or auxiliary material can be solid or liquid, and they are typically the material commonly used during formulation,
For example natural or regeneration mineral matter, solvent, dispersant, wetting agent, adhesive, thickener, adhesive.
The application process of the present composition includes being used for the composition of the present invention into the aerial part of plant growth, especially
It is leaf portion or blade face.It can select to soak seed or be applied to controlling object surface.The frequency and amount of application of administration depend on pathogen
Biology and weather life condition.The growth place of plant, such as rice field can be soaked with the liquid preparation of composition, or
Composition is applied in soil by person in solid form, such as in granular form (soil application), and composition can be by soil through planting
Thing root enters in plant (systemic action).
The composition of the present invention can be prepared into acceptable various formulations on agricultural chemicals, including but not limited to missible oil, suspension
Agent, wettable powder, water dispersible granules, pulvis, granula, aqua, aqueous emulsion, microemulsion, poison bait, mother liquor, female powder etc., in one kind
In preferred scheme, formulation of the invention uses wettable powder, aqua, water dispersible granules, aqueous emulsion or microemulsion.According to these
The property of composition and the purpose to be reached using composition and ambient conditions, can be selected composition to spray, more
Mist, dust, broadcast sowing or sprinkle the method poured or the like and apply.
The composition of the present invention can be prepared into various formulations with known method, can be by active ingredient with helping
Agent, such as solvent, solid carrier, it is necessary to when can uniformly mix, grind together with surfactant, be prepared into required agent
Type.
Above-mentioned solvent may be selected from aromatic hydrocarbon, preferably containing 8-12 carbon atom, such as xylene mixture or substituted benzene, phthalein
The octanoic acid of esters of gallic acid, such as Dibutyl phthalate or phthalandione two, such as fat hydrocarbon, thiacyclohexane or paraffin, alcohol and ethylene glycol and their ether
And ester, such as ethanol, ethylene glycol, ethylene glycol monomethyl；Ketone, such as cyclohexanone, such as highly polar solvent, N- methyl -2- pyrrolidines
Ketone, dimethyl sulfoxide (DMSO) or dimethylformamide, and vegetable oil or vegetable oil, such as soybean oil.
Above-mentioned solid carrier, is such as used for the typically natural mineral fillers, such as talcum, kaolinite of pulvis and dispersible dose
Soil, montmorillonite or atlapulgite.In order to manage the physical property of composition, polymolecularity silicic acid or polymolecularity can also be added
Adsorpting polymerization thing carrier, such as granulated adsorptive carriers or non-adsorbed carrier, suitable granulated adsorptive carriers are porous types, such as floating
Stone, bentonite or bentonite；Suitable non-adsorbed carrier such as calcite or sand.Further, it is possible to use substantial amounts of inorganic in nature or having
The prefabricated material granulated of machine property is used as carrier, particularly dolomite.
The chemical property of active ingredient in the composition of the present invention, suitable surfactant is sulfomethylated lignin
Acid, naphthalene sulfonic acids, phenolsulfonic acid, alkali salt or amine salt, alkylaryl sulfonates, alkyl sulfate, alkylsulfonate, fat
The condensation product of alcohol sulfate, aliphatic acid and sulphated fatty alcohol glycol ether, also sulfonated naphthalene and naphthalene derivatives and formaldehyde, naphthalene or
Naphthalene sulfonic acids and phenol and the condensation product of formaldehyde, NONIN HS 240, ethoxylated isooctyl-phenol, octyl phenol, nonyl phenol,
Alkylaryl polyglycol ether, tributyl benzene polyglycol ether, three stearyl phenyl polyglycol ethers, alkyl aryl polyether alcohol,
Ethoxylated castor oil, polyoxyethylene alkyl ether, ethylene oxide condensation product, ethoxylation polyoxypropylene, bay acid polyethylene glycol
Ether acetal, sorbitol ester, lignin sulfite waste liquor and methylcellulose.
Two kinds of active ingredients show as synergistic effect in the composition of the present invention, and the activity of said composition is than using individualized
The expected summation of activity of compound, and the independent activity of single compound are more notable.Synergistic effect shows as allowing amount of application
Reduce, broader antifungal control spectrum, instant effect, more longlasting prevention effect, by only once or a small number of several times using more
Good control plant pest fungi and broaden the possible administration interval time.These characteristics are plant epiphyte control practices
During especially need.
In terms of the microbicide compositions of the present invention can be applied to agriculture field preventing and treating corps diseases, targeted specific disease
Disease includes but is not limited to wheat diseases (such as：Wheat scab, wheat powdery mildew, wheat rust etc.), rice disease (such as：Paddy rice
Banded sclerotial blight, rice green smut, rice blast, paddy bacterial streak etc.), maize diseases (such as：Smut of maize, corn are big
Pinta, corn southern leaf blight), cucumber disease (such as：The bacillary angle spot of cucumber downy mildew, powdery mildew of cucumber, cucumber anthracnose, cucumber
Disease etc.), tomato disease (such as：Anthracnose of tomato, graw mold of tomato, tomato bacterial angular leaf spot etc.), grape disease (such as：Grape
Downy mildew, grape grey mould, uncinula necator), apple disease (such as ring rot of apple, apple anthracnose), citrus disease (mandarin orange
Tangerine canker, citrus scab simultaneously, citrus anthracnose), tobacco diseases (wildfire) etc..
The other features shown of the bactericidal composition of the present invention are mainly shown as：1st, composition mixture of the invention tool
There is obvious synergistic effect；2nd, because two single dose chemical constitutions of this composition are widely different, the mechanism of action is entirely different, no
There is cross resistance, can delay two single doses that produced resistance problem is used alone；3rd, composition of the invention to crop safety,
Preventive effect is good.Tests prove that, microbicide compositions chemical property of the present invention is stable, and synergy significantly, is shown bright to controlling object
Aobvious synergy and complementation.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that specific embodiment described herein is not used to limit only to explain the present invention
The fixed present invention, any modifications, equivalent replacements and improvementsmade within the spirit and principles of the invention, should be included in
Within protection scope of the present invention.
Percentage is weight percentage in all formulas of following examples.The processing work of the various preparations of the present composition
Skill is prior art, can be varied from according to different situations.
First, formulation prepares embodiment
(1) processing of aqua and embodiment
By active component activity packet A and active component B, with each component such as dispersant, wetting agent, antifreezing agent and water by matching somebody with somebody
The ratio of side is well mixed, and obtains semi-finished product, and the filtering that is mixed with water is mended after analysis and is got product.
(1) active component A (Physcion) prepares aqua with polyoxin
Embodiment 1：20.5% Physcion polyoxin aqueous solution (1:40)
Physcion 0.5%, polyoxin 20%, xanthans 5%, sodium lignin sulfonate 8%, toluene 6%, ethylene glycol
5%, water complements to 100%.
Embodiment 2：11% Physcion polyoxin aqueous solution (1:10)
Physcion 1%, polyoxin 10%, carboxymethyl cellulose 5%, methyl naphthalene sulfonate formaldehyde condensate 8%,
Dimethylbenzene 6%, glycerine 5%, water complements to 100%.
Embodiment 3：25.5% Physcion polyoxin aqueous solution (1:50)
Physcion 0.5%, polyoxin 25%, remaining component is prepared according to the method for embodiment 1.
(2) active component A (aloe-emodin) polyoxin is with preparing aqua
Embodiment 4：20.5% aloe-emodin polyoxin aqueous solution
Aloe-emodin 0.5%, polyoxin 20%, remaining component is prepared according to the method for embodiment 1.
Embodiment 5：11% aloe-emodin polyoxin aqueous solution
Aloe-emodin 1%, polyoxin 10%, remaining component is prepared according to the method for embodiment 2.
Embodiment 6：25.5% aloe-emodin polyoxin aqueous solution
Aloe-emodin 0.5%, polyoxin 25%, remaining component is prepared according to the method for embodiment 1.
(2) processing of wettable powder and embodiment
Active components A and B activity composition and various auxiliary agents and filler etc. are sufficiently mixed in proportion, through ultrafine crusher powder
Obtained wettable powder after broken.
(1) active component A (Physcion) prepares wettable powder with polyoxin
Embodiment 7：6% Physcion Wettable polyoxin powder (5:1)
Physcion 5%, polyoxin 1%, xanthans 5%, lignosulfonates 6%, alkylsulfonate 6%, spray
Intercalation native 8%, precipitated calcium carbonate complements to 100%.
Embodiment 8：10.5% Physcion Wettable polyoxin powder (1:20)
Physcion 0.5%, polyoxin 10%, remaining component is prepared according to the method for embodiment 7.
Embodiment 9：56.8% Physcion Wettable polyoxin powder (1:70)
Physcion 0.8%, polyoxin 56%, remaining component is prepared according to the method for embodiment 7.
Embodiment 10：50.5% Physcion Wettable polyoxin powder (1:100)
Physcion 0.5%, polyoxin 50%, remaining component is prepared according to the method for embodiment 7.
(2) active component A (aloe-emodin) prepares wettable powder with polyoxin
Embodiment 11：6% aloe-emodin Wettable polyoxin powder
Aloe-emodin 5%, polyoxin 1%, remaining component is prepared according to the method for embodiment 7.
Embodiment 12：10.5% aloe-emodin Wettable polyoxin powder
Aloe-emodin 0.5%, polyoxin 10%, remaining component is prepared according to the method for embodiment 7.
Embodiment 13：56.8% aloe-emodin Wettable polyoxin powder
Aloe-emodin 0.8%, polyoxin 56%, remaining component is prepared according to the method for embodiment 7.
Embodiment 14：50.5% aloe-emodin Wettable polyoxin powder
Aloe-emodin 0.5%, polyoxin 50%, remaining component is prepared according to the method for embodiment 7.
(3) processing of microemulsion and embodiment
By active components A and active component B, mixed in the ratio of formula with solvent, surfactant, stabilizer, water
It is even, microemulsion product is made afterwards.
(1) active component A (Physcion) prepares microemulsion with polyoxin
Embodiment 15：7.5% Physcion polyoxin microemulsion (1:2)
Physcion 2.5%, polyoxin 5%, dimethyl sulfoxide (DMSO) 15%, the condensation of diphenyl phenol polyethenoxy polyformaldehyde
Thing 8%, magnesium stearate 6%, water complements to 100%.
Embodiment 16：15.5% Physcion polyoxin microemulsion (1:30)
Physcion 0.5%, polyoxin 15%, remaining component is prepared according to the method for embodiment 15.
Embodiment 17：45.5% Physcion polyoxin microemulsion (1:90)
Physcion 0.5%, polyoxin 45%, remaining component is prepared according to the method for embodiment 15.
(2) active component A (aloe-emodin) prepares microemulsion with polyoxin
Embodiment 18：7.5% aloe-emodin polyoxin microemulsion
Aloe-emodin 2.5%, polyoxin 5%, remaining component is prepared according to the method for embodiment 15.
Embodiment 19：15.5% aloe-emodin polyoxin microemulsion
Aloe-emodin 0.5%, polyoxin 15%, remaining component is prepared according to the method for embodiment 15.
Embodiment 20：45.5% aloe-emodin polyoxin microemulsion
Aloe-emodin 0.5%, polyoxin 45%, remaining component is prepared according to the method for embodiment 15.
2nd, drug effect checking test
(1) Assays Example
The incidence of whole strain blade is investigated according to experiment grade scale, disease index and prevention effect is calculated.
Prevention effect is converted into niqueMin (y), liquor strength (μ g/ml) is converted into logarithm value (x), with least square method
Concentration EC50 in calculating virulence equation and suppressing, the toxicity index and co-toxicity coefficient (CTC) of medicament are calculated according to the abundant methods of Sun Yun.
Survey toxicity index (ATI)=(standard agent EC50/ reagent agent EC50) * 100
A percentage composition+B medicament toxicity index * mixtures in theoretical toxicity index (TTI)=A medicament toxicity index * mixtures
Middle B percentage composition
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (ATI)/mixture theoretical toxicity index (TTI)] * 100
CTC≤80, composition shows as antagonism, 80 ＜ CTC ＜ 120, and composition shows as summation action, and CTC >=
120, composition shows as synergistic effect.
1st, Physcion and polyoxin compounding are tested tomato rust toxicity test
The Physcion of table 1. is compounded to tomato rust toxicity test interpretation of result with polyoxin
As a result (table 1) shows, Physcion is with polyoxin 1:In 0.5~100 ratio range, Physcion with
Polyoxin is compounded to be significantly improved to the prevention effect of tomato rust, illustrates that the two compounding has significantly to the preventing and treating of tomato rust
Synergistic effect.And summation action is then shown outside this range.
2nd, aloe-emodin and polyoxin compounding are tested wheat sharp eyespot toxicity test
The aloe-emodin of table 2. is compounded to wheat sharp eyespot toxicity test interpretation of result with polyoxin
As a result (table 2) shows, aloe-emodin is with polyoxin 1:In 0.5~100 ratio range, aloe-emodin with
Polyoxin is compounded to be significantly improved to the prevention effect of wheat sharp eyespot, illustrates that the two compounding has significantly to wheat sharp eyespot preventing and treating
Synergistic effect.And summation action is then shown outside this range.
(2) field efficacy checking test
Test method：At the initial stage of a disease, first time spraying is carried out immediately, and second of dispenser is carried out after 7 days, 4 are each handled
Individual cell, each square meter of cell 20.In 11 days investigation statisticses incidences before medicine and after second medicine, each 5 points of cell is random
Sampling, 5 plants of crops of every investigation, investigates percentage and classification that the lesion area in whole strain per blade accounts for blade area, calculates
Disease index and prevention effect.
It is expected that preventive effect (%)=X+Y-XY/100 (wherein, X, Y are single dose preventive effect)
Grade scale：
0 grade：Disease-free spot；
1 grade：Leaf spot lesion is less than 5, and length is less than 1cm；
3 grades：Leaf spot lesion 6-10, part scab length is more than 1cm；
5 grades：Leaf spot lesion 11-25, part scab is linked to be piece, and lesion area accounts for the 10-25% of leaf area；
7 grades：Leaf spot lesion more than 26, scab is linked to be piece, and lesion area accounts for the 26-50% of leaf area；
9 grades：Scab is linked to be piece, and more than 50% or the full leaf that lesion area accounts for leaf area are withered.
1st, Physcion and polyoxin compounding field efficacy experiment
The Physcion of table 3 is with polyoxin to apple tree graywall prevention effect
Measurement result (table 4) shows that the compounding of Physcion and polyoxin is substantially carried to apple tree graywall preventive effect
Height, illustrates that the two compounding has significant synergistic effect to apple tree graywall.
2nd, aloe-emodin and polyoxin compounding field efficacy experiment
The aloe-emodin of table 4 is with polyoxin mixture to gray mold of cucumber prevention effect
Measurement result (table 4) shows that aloe-emodin is significantly improved with polyoxin mixture to the preventive effect of gray mold of cucumber,
Illustrate that the two compounding has significant synergistic effect to gray mold of cucumber.
Claims (10)
1. a kind of microbicide compositions, it is characterised in that described composition includes two kinds of active components of A and B, active component A is
Anthraquinone analog compound, active component B is polyoxin, and active component A and active component B weight ratio are 1:0.2~100, its
In, the one kind of anthraquinone analog compound in Physcion or aloe-emodin.
2. microbicide compositions according to claim 1, it is characterised in that active component A and active component B weight ratio
For 1:1~70.
3. microbicide compositions according to claim 1, it is characterised in that the weight ratio of Physcion and polyoxin
For 1:1~50.
4. microbicide compositions according to claim 1, it is characterised in that the weight ratio of aloe-emodin and polyoxin
For 1:1~50.
5. the microbicide compositions according to any one in Claims 1 to 4, it is characterised in that said composition by activity into
Divide and the formulation allowed on agricultural chemicals is made with insecticides adjuvant or auxiliary material.
6. microbicide compositions according to claim 5, it is characterised in that said composition by 2~85% parts by weight activity
The formulation allowed on agricultural chemicals is made in the insecticides adjuvant or auxiliary material of component and 98~15% parts by weight.
7. microbicide compositions according to claim 5, it is characterised in that described formulation be wettable powder, aqua,
Water dispersible granules, aqueous emulsion or microemulsion.
8. the microbicide compositions according to claim 5 or 6, it is characterised in that the insecticides adjuvant or auxiliary material, which are selected from, to be carried
One or more in body, solvent, dispersant, wetting agent, adhesive, thickener, adhesive, surfactant and fertilizer.
9. the microbicide compositions in claim 1~8 described in any one are in terms of agriculture field preventing and treating corps diseases
Purposes.
10. the purposes described in claim 9, it is characterised in that fungi or phytosis of the described corps diseases for crops
Evil；
Described crops are veterinary antibiotics and cereal.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109938045A (en) * | 2019-02-27 | 2019-06-28 | 江苏辉丰生物农业股份有限公司 | Composition pesticide containing toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Physcion |
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