CN106719646A - A kind of microbicide compositions comprising anthraquinone analog compound and methoxy acrylic - Google Patents
A kind of microbicide compositions comprising anthraquinone analog compound and methoxy acrylic Download PDFInfo
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- CN106719646A CN106719646A CN201710007322.2A CN201710007322A CN106719646A CN 106719646 A CN106719646 A CN 106719646A CN 201710007322 A CN201710007322 A CN 201710007322A CN 106719646 A CN106719646 A CN 106719646A
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- China
- Prior art keywords
- physcion
- emodin
- aloe
- fluoxastrobin
- pyraclostrobin
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/06—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing keto or thioketo groups as part of a ring, e.g. cyclohexanone, quinone; Derivatives thereof, e.g. ketals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/88—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with three ring hetero atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
Abstract
The invention provides a kind of microbicide compositions comprising anthraquinone analog compound and methoxy acrylic, said composition includes two kinds of effective constituents As and B, active component A is selected from the one kind in Physcion and aloe-emodin in anthraquinone analog compound, active component B is in methoxy acrylic bactericide, selected from the one kind in pyraclostrobin, ZEN 90160, Fluoxastrobin and fluoxastrobin, the weight ratio between two components is 1:0.1~70.Present invention also offers the Preparation method and use of said composition.Result of the test shows that the above-mentioned bactericidal composition synergy that the present invention is provided is obvious, it is often more important that amount of application is reduced, use cost reduction.The bactericidal composition can effectively prevent and treat some specific bacteriums or the fungal disease of crop.Compounded by by the bactericide of different mechanism of action and the mode of action, there is effect well for expanding fungicidal spectrum and delaying germ resistance and improve the aspects such as prevention effect.
Description
Technical field
It is more particularly to a kind of with the bactericidal composition for improving performance, tool the invention belongs to agriculture plant protection field
Say it is to be related to a kind of microbicide compositions comprising anthraquinone analog compound and methoxy acrylic body.
Background technology
Physcion and aloe-emodin etc. belong to anthraquinone analog compound.In field of medicaments, these compounds are extensive
Using such as immunoregulation effect, scavenging activated oxygen effect, antibacterial, anti-inflammatory, antivirus action, diuresis, to cerebrum ischemia
The protective effect of damage, cardiovascu- lar effects, antitumor action.In recent years, these anthraquinone analog compounds are just progressively employed
In agriculture field, for preventing and treating fungi or bacterial disease, powdery mildew, downy mildew, gray mold to veterinary antibiotics, cereal etc.,
The multiple diseases such as anthracnose have good prevention effect, environmentally friendly while to people and animals' low toxicity, with other chemical agents without
Cross resistance, with preferable Uptake and translocation effect, lasting effect is strong.Its bactericidal action mechanism is by disturbing disease fungus cell
The biosynthesis of wall chitin, suppresses sprouting, the growth of mycelia, the formation of haustorium of pathogen spore, so as to block disease
Spread, also can induce crop and produce degeneration-resistant defense reaction, reach the effect of diseases prevention.
Pyraclostrobin, ZEN 90160, fluoxastrobin or Fluoxastrobin etc. belong to methoxy acrylic bactericide, tool
Have protection, treat, root out, osmosis, the features such as without carcinogenic and mutagenesis, can effectively prevent and treat sac fungus, basidiomycetes, Fungi Imperfecti
With the fungus-caused disease such as oomycetes.
Pyraclostrobin (pyraclostrobin) is new-type wide-spectrum bactericide.The mechanism of action：For mitochondrial respiratory suppresses
Agent be by synthesizing in cytochromes in prevent electro transfer.With protection, treatment, blade infiltration conduction.Pyrazoles ether bacterium
Emulsifiable concentrate shows have to powdery mildew of cucumber, downy mildew and banana freckle, leaf spot, sclerotiniose etc. through field control effectiveness test result
Preferable prevention effect.
ZEN 90160 (Picoxystrobin) is systemic fungicide, and controlling object wide spectrum is mainly used in preventing and treating wheat class
Foliage disease such as leaf blight, leaf rust, glume blight, brown spot, powdery mildew etc., with other methoxy acrylic bactericide phases
Than ZEN 90160 has stronger therapeutic effect to wheat leaf blessing disease, net blotch and moire disease.
Fluoxastrobin (Fluoxastrobin) mechanism of action is also mitochondrial respiratory inhibitor, i.e., by cytochrome b
Electro transfer suppresses mitochondrial breathing and between C1.Fluoxastrobin has excellent preventive effect to target etc., has to late blight
Good preventive effect；There is excellent preventive effect to vegetable Lay leaf spot etc., there is good preventive effect to downy mildew.
Fluoxastrobin (Azoxystrobin) belong to efficiently, wide spectrum series bactericidal agent, to almost all of mycota, (sac fungus is sub-
Door, Basidiomycotina, Mastigomycotina and Deuteromycotina) disease for example powdery mildew, rust, glume blight, net blotch, downy mildew,
Rice blast etc. has good activity.Can be used for cauline leaf spraying, Seed Treatment, can also carry out soil treatment, be mainly used in cereal,
Paddy rice, peanut, grape, potato, fruit tree, vegetables, coffee, lawn etc..
Actual agricultural chemicals experience have shown that, repeat and single-minded apply a kind of reactive compound to prevent and treat harmful fungoid very
The fast selective of fungal bacterial strain will be caused in the case of many, to reduce the danger of refractory fungal bacterial strain selectivity, at present generally
Harmful fungoid is prevented and treated using the mixture of different activities compound.Enter by by the reactive compound with the different mechanisms of action
Row combination, can delaying drug resistance generation, reduction amount of application, reduction cost accounting.
The content of the invention
The purpose of the present invention is directed to bactericide resistance and pedo relict problem in actual applications, filters out difference and kills
The bactericide of bacterium principle is compounded, and obtains a kind of new microbicide compositions, to improve bactericidal agent for preventing and treating effect, delaying drug resistance
Produce, reduce amount of application, reduce cost accounting.
Prevented and treated in agriculture field it is a further object to provide comprising two kinds of effective constituents As and B bactericidal compositions
The application of corps diseases.
The purpose of the present invention can be reached by following measures：
A kind of composition pesticide with synergistic effect, said composition includes two kinds of active components of A and B, and active component A is
In anthraquinone analog compound, selected from the one kind in Physcion or aloe-emodin, active component B is methoxy acrylic
In bactericide, selected from the one kind in pyraclostrobin, ZEN 90160, fluoxastrobin or Fluoxastrobin, the weight ratio between two components
It is 1:0.1~70.
Inventor is found by experiment that composition of the invention is for preventing and treating crops bacterium or fungal disease, preventing
Control synergy obvious, it is often more important that amount of application is reduced, reduce use cost.Compound structure type containing component A Yu component B
Difference, mechanism of action is different, and both can expand fungicidal spectrum at compounding, and can to a certain extent delay pathogen resistance
Produce the no interactions resistance and development speed, and component A and component B between.
Weight ratio between two components in microbicide compositions of the present invention is 1:0.1~70.To make the medicine between two components
Effect synergistic effect is more notable, and the weight ratio between the component of weight two of component A and component B can further optimize, specifically,
Physcion can further be optimized to 1 with pyraclostrobin, Fluoxastrobin, fluoxastrobin, the proportioning of ZEN 90160:1~60,
Aloe-emodin can further be optimized to 1 with pyraclostrobin, Fluoxastrobin, fluoxastrobin, the proportioning of ZEN 90160:1~50.
In a kind of preferred scheme, the weight ratio between A and the components of B two arbitrarily can enter in the range of following proportionings
Row adjustment 10:1、9:1、8:1、7:1、6:1、5:1、4:1、3:1、2:1、1:1、1:2、1:3、1:4、1:5、1:6、1:7、1:8、1:
9、1:10、1:11、1:12、1:13、1:14、1:15、1:16、1:17、1:18、1:19、1:20、1:21、1:22、1:23、1:24、
1:25、1:26、1:27、1:28、1:29、1:30、1:31、1:32、1:33、1:34、1:35、1:36、1:37、1:38、1:39、1:
40、1:41、1:42、1:43、1:44、1:45、1:46、1:47、1:48、1:49、1:50、1:51、1:52、1:53、1:54、1:
55、1:56、1:57、1:58、1:59、1:60、1:61、1:62、1:63、1:64、1:65、1:66、1:67、1:68、1:69、1:
70, it is also possible to selected in the range of two proportionings of any of the above are constituted, these ratios can be understood as weight ratio,
Mol ratio can be included.
Composition of the invention can be made the formulation allowed on agricultural chemicals by active component and insecticides adjuvant or auxiliary material.Enter one
Step, said composition constitutes agriculture by the active component of 2~85% weight portions and the insecticides adjuvant of 98~15% weight portions or auxiliary material
The formulation allowed on medicine.
The invention provides the bactericidal composition comprising component A and component B in terms of agriculture field preventing and treating corps diseases
Purposes, particularly in terms of fungi or bacterial disease that agriculture field prevents and treats some crops (such as veterinary antibiotics, cereal)
Purposes.
Above-mentioned composition can specifically include insecticides adjuvant or auxiliary material, for example carrier, solvent, dispersant, wetting agent, gluing
One or more in agent, thickener, adhesive, surfactant or fertilizer etc..Can mix during administration conventional
Auxiliary agent.
Suitable auxiliary agent or auxiliary material can be solid or liquid, and they are typically the material commonly used during formulation,
For example natural or regeneration mineral matter, solvent, dispersant, wetting agent, adhesive, thickener, adhesive.
The application process of the present composition includes being used for composition of the invention the aerial part of plant growth, especially
It is leaf portion or blade face.Can select to soak seed or be applied to controlling object surface.The frequency and amount of application of administration depend on pathogen
Biology and weather life condition.Can be by the growth place of plant, such as rice field is soaked with the liquid preparation of composition, or
In solid form be applied in soil composition by person, and such as in granular form (soil application), composition can be by soil through planting
Thing root enters in plant (systemic action).
Composition of the invention can be prepared into acceptable various formulations on agricultural chemicals, including but not limited to missible oil, suspension
Agent, wettable powder, water dispersible granules, pulvis, granula, aqua, aqueous emulsion, microemulsion, encapsulated form, mother liquor, female powder etc.,
In a kind of preferred scheme, formulation of the invention uses wettable powder, suspending agent, water dispersible granules, aqueous emulsion or microemulsion.Root
The purpose and ambient conditions to be reached according to the property of these compositions and using composition, can select composition to spray
Mist, atomizing, dust, broadcast sowing or sprinkle the method poured or the like and apply.
Composition of the invention can be prepared into various formulations with known method, by active ingredient and auxiliary agent, such as solvent,
Solid carrier, it is necessary to when can also uniformly mix together with surfactant, grind, be prepared into required formulation.
Above-mentioned solvent may be selected from aromatic hydrocarbon, preferably containing 8-12 carbon atom, such as xylene mixture or substituted benzene, phthalein
The octanoic acid of esters of gallic acid, such as Dibutyl phthalate or phthalandione two, such as fat hydrocarbon, thiacyclohexane or paraffin, alcohol and ethylene glycol and their ether
And ester, such as ethanol, ethylene glycol, ethylene glycol monomethyl；Ketone, such as cyclohexanone, such as highly polar solvent, N- methyl -2- pyrrolidines
Ketone, dimethyl sulfoxide (DMSO) or dimethylformamide, and vegetable oil, such as soybean oil.
Above-mentioned solid carrier, is such as used for pulvis and dispersibles the typically natural mineral fillers, such as talcum, kaolinite of agent
Soil, montmorillonite or atlapulgite.In order to manage the physical property of composition, it is also possible to add polymolecularity silicic acid or polymolecularity
Adsorpting polymerization thing carrier, such as granulated adsorptive carriers or non-adsorbed carrier, suitable granulated adsorptive carriers are porous types, such as floating
Stone, bentonite or bentonite；Suitable non-adsorbed carrier such as calcite or sand.Further, it is possible to use substantial amounts of inorganic in nature or having
The prefabricated material for granulating of machine property is used as carrier, particularly dolomite.
The chemical property of the active ingredient in composition of the invention, suitable surfactant is sulfomethylated lignin
Acid, naphthalene sulfonic acids, phenolsulfonic acid, alkali salt or amine salt, alkylaryl sulfonates, alkyl sulfate, alkylsulfonate, fat
The condensation product of alcohol sulfate, aliphatic acid and sulphated fatty alcohol glycol ether, also sulfonated naphthalene and naphthalene derivatives and formaldehyde, naphthalene or
Naphthalene sulfonic acids and phenol and the condensation product of formaldehyde, NONIN HS 240, ethoxylated isooctyl-phenol, octyl phenol, nonyl phenol,
Alkylaryl polyglycol ether, tributyl benzene polyglycol ether, three stearyl phenyl polyglycol ethers, alkyl aryl polyether alcohol,
Ethoxylated castor oil, polyoxyethylene alkyl ether, ethylene oxide condensation product, ethoxylation polyoxypropylene, bay acid polyethylene glycol
Ether acetal, sorbitol ester, lignin sulfite waste liquor and methylcellulose.
Two kinds of active ingredients show as synergistic effect in composition of the invention, and the activity of said composition is than using individualized
The expected summation of activity of compound, and the independent activity of single compound is more notable.Synergistic effect shows as allowing amount of application
Reduce, broader antifungal control spectrum, instant effect, more longlasting prevention effect, by only once or minority is several times using just
Plant pest fungi can preferably be controlled and the possible administration interval time is broadened.These characteristics are plant epiphyte controls
Especially needed in practice process processed.
Microbicide compositions of the invention can be applied to agriculture field preventing and treating corps diseases aspect, farming referred herein
Thing disease particularly uncinula necator, powdery mildew of cucumber, cucumber downy mildew, balsam pear powdery mildew, graw mold of tomato, wheat white powder
Disease, rice blast.But composition of the invention is in addition to it can prevent and treat foregoing disease, moreover it is possible to the specific illness of preventing and treating include but
It is not limited to wheat diseases (such as：Wheat scab, wheat powdery mildew, wheat rust etc.), rice disease (such as：Rice sheath blight disease, water
Rice false smut, paddy bacterial streak etc.), maize diseases (such as：Smut of maize, the leaf blight of corn, corn southern leaf blight), cucumber
Disease is (such as：Powdery mildew of cucumber, cucumber anthracnose, gray mold of cucumber, cucumber bacterial angular leaf spot etc.), tomato disease (such as：Tomato
Powdery mildew, anthracnose of tomato, tomato virus disease, tomato bacterial angular leaf spot etc.), grape disease (such as：Downy mildew of garpe, grape
Gray mold), apple disease (such as：Ring rot of apple, apple anthracnose etc.), citrus disease (such as：Oranges and tangerines scab simultaneously, oranges and tangerines anthrax
Disease), tobacco diseases (such as：Wildfire, Alternaria alternate), rape disease (such as：Sclerotinia rot of colza), cotton disease (such as：Cotton
Flower verticillium wilt, cotton wilt) etc..
Other features that bactericidal composition of the invention shows are mainly：1st, composition mixture of the invention has obvious
Synergistic effect；2nd, because two single dose chemical constitutions of this composition are widely different, the mechanism of action is entirely different, in the absence of friendship
Mutual resistance, can delay two single doses that produced resistance problem is used alone；3rd, composition of the invention is to crop safety, preventive effect
It is good.Tests prove that, microbicide compositions stable chemical nature of the present invention, synergy significantly, shows significantly to controlling object
Synergy and complementation.
Specific embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that specific embodiment described herein is only used to explain the present invention, limit is not used to
The fixed present invention, all any modification, equivalent and improvement made within the spirit and principles in the present invention etc., should be included in
Within protection scope of the present invention.
Percentage is weight percentage in all formulas of following examples.The processing work of the various preparations of the present composition
Skill is prior art, can be varied from according to different situations.
First, formulation prepares embodiment
(1) processing of suspending agent and embodiment
By active component activity packet A and active component B, with each component such as dispersant, wetting agent, thickener and water by matching somebody with somebody
Side ratio be well mixed, through sand milling and/or high speed shear after, obtain semi-finished product, after analysis mend be mixed with water filtering i.e.
Obtain finished product.
(1) active component A (Physcion) prepares suspending agent with pyraclostrobin
Embodiment 1：40% Physcion pyraclostrobin suspending agent
Physcion 20%, pyraclostrobin 20%, bentonite 3%, Magnesiumaluminumsilicate 2%, xanthans 1%, ethylene glycol
3%, calcium lignosulfonate 6%, water complements to 100%..
Embodiment 2：62% Physcion pyraclostrobin suspending agent
Physcion 2%, pyraclostrobin 60%, Sodium Benzoate 4%, white carbon 3%, glycerine 5%, poly alkyl alcohol
Oxygen ethene ether phosphate 6%, water complements to 100%.
(2) active component A (Physcion) prepares suspending agent with ZEN 90160
Embodiment 3：40% Physcion chlorfenapyr suspending agent
Physcion 20%, ZEN 90160 20%, remaining component is prepared according to the method for embodiment 1.
Embodiment 4：62% Physcion chlorfenapyr suspending agent
Physcion 2%, ZEN 90160 60%, remaining component is prepared according to the method for embodiment 2.
(3) active component A (Physcion) prepares suspending agent with Fluoxastrobin
Embodiment 5：40% Physcion Fluoxastrobin suspending agent
Physcion 20%, Fluoxastrobin 20%, remaining component is prepared according to the method for embodiment 1.
Embodiment 6：62% Physcion Fluoxastrobin suspending agent
Physcion 2%, Fluoxastrobin 60%, remaining component is prepared according to the method for embodiment 2.
(4) active component A (Physcion) prepares suspending agent with fluoxastrobin
Embodiment 7：40% Physcion fluoxastrobin suspending agent
Physcion 20%, fluoxastrobin 20%, remaining component is prepared according to the method for embodiment 1.
Embodiment 8：62% Physcion fluoxastrobin suspending agent
Physcion 2%, fluoxastrobin 60%, remaining component is prepared according to the method for embodiment 2.
(5) active component A (aloe-emodin) prepares suspending agent with pyraclostrobin
Embodiment 9：40% aloe-emodin pyraclostrobin suspending agent
Aloe-emodin 20%, pyraclostrobin 20%, remaining component is prepared according to the method for embodiment 1.
Embodiment 10：62% aloe-emodin pyraclostrobin suspending agent
Aloe-emodin 2%, pyraclostrobin 60%, remaining component is prepared according to the method for embodiment 2.
(6) active component A (aloe-emodin) prepares suspending agent with ZEN 90160
Embodiment 11：40% aloe-emodin chlorfenapyr suspending agent
Aloe-emodin 20%, ZEN 90160 20%, remaining component is prepared according to the method for embodiment 1.
Embodiment 12：62% aloe-emodin chlorfenapyr suspending agent
Aloe-emodin 2%, ZEN 90160 60%, remaining component is prepared according to the method for embodiment 2.
(7) active component A (aloe-emodin) prepares suspending agent with Fluoxastrobin
Embodiment 13：40% aloe-emodin Fluoxastrobin suspending agent
Aloe-emodin 20%, Fluoxastrobin 20%, remaining component is prepared according to the method for embodiment 1.
Embodiment 14：62% aloe-emodin Fluoxastrobin suspending agent
Aloe-emodin 2%, Fluoxastrobin 60%, remaining component is prepared according to the method for embodiment 2.
(8) active component A (aloe-emodin) prepares suspending agent with fluoxastrobin
Embodiment 15：40% aloe-emodin fluoxastrobin suspending agent
Aloe-emodin 20%, fluoxastrobin 20%, remaining component is prepared according to the method for embodiment 1.
Embodiment 16：62% aloe-emodin fluoxastrobin suspending agent
Aloe-emodin 2%, fluoxastrobin 60%, remaining component is prepared according to the method for embodiment 2.
(2) processing of aqueous emulsion and embodiment
By active component activity packet A and active component B, with each component such as dispersant, wetting agent, thickener and water by matching somebody with somebody
Side ratio be well mixed, through sand milling and/or high speed shear after, obtain semi-finished product, after analysis mend be mixed with water filtering i.e.
Obtain finished product.
(1) active component A (Physcion) prepares aqueous emulsion with pyraclostrobin
Embodiment 17：22% Physcion pyraclostrobin aqueous emulsion
Physcion 20%, pyraclostrobin 2%, alkyl polyoxyethanyl ether sulfonate 3%, polyoxyethylene octylphenyl
Ether 3%, neopelex 3%, glycerine 3%, sodium carboxymethyl starch 1%, water complements to 100%.
Embodiment 18：22% Physcion pyraclostrobin aqueous emulsion
Physcion 2%, pyraclostrobin 20%, dimethyl sulfoxide (DMSO) 6%, dimethylformamide 5%, isooctyl acetate
5%th, calcium dodecyl benzene sulfonate 2%, water complements to 100%.
(2) active component A (Physcion) prepares aqueous emulsion with ZEN 90160
Embodiment 19：22% Physcion ZEN 90160 aqueous emulsion
Physcion 20%, ZEN 90160 2%, remaining component is prepared according to the method for embodiment 17.
Embodiment 20：22% Physcion ZEN 90160 aqueous emulsion
Physcion 2%, ZEN 90160 20%, remaining component is prepared according to the method for embodiment 18.
(3) active component A (Physcion) prepares aqueous emulsion with Fluoxastrobin
Embodiment 21：22% Physcion azoxystrobin water emulsion
Physcion 20%, Fluoxastrobin 2%, remaining component is prepared according to the method for embodiment 17.
Embodiment 22：22% Physcion azoxystrobin water emulsion
Physcion 2%, Fluoxastrobin 20%, remaining component is prepared according to the method for embodiment 18.
(4) active component A (Physcion) prepares aqueous emulsion with fluoxastrobin
Embodiment 23：22% Physcion fluoxastrobin aqueous emulsion
Physcion 20%, fluoxastrobin 2%, remaining component is prepared according to the method for embodiment 17.
Embodiment 24：22% Physcion fluoxastrobin aqueous emulsion
Physcion 2%, fluoxastrobin 20%, remaining component is prepared according to the method for embodiment 18.
(5) active component A (aloe-emodin) prepares aqueous emulsion with pyraclostrobin
Embodiment 25：22% aloe-emodin pyraclostrobin aqueous emulsion
Aloe-emodin 20%, pyraclostrobin 2%, remaining component is prepared according to the method for embodiment 17.
Embodiment 26：22% aloe-emodin pyraclostrobin aqueous emulsion
Aloe-emodin 2%, pyraclostrobin 20%, remaining component is prepared according to the method for embodiment 18.
(6) active component A (aloe-emodin) prepares aqueous emulsion with ZEN 90160
Embodiment 27：22% aloe-emodin ZEN 90160 aqueous emulsion
Aloe-emodin 20%, ZEN 90160 2%, remaining component is prepared according to the method for embodiment 17.
Embodiment 28：22% aloe-emodin ZEN 90160 aqueous emulsion
Aloe-emodin 2%, ZEN 90160 20%, remaining component is prepared according to the method for embodiment 18.
(7) active component A (aloe-emodin) prepares aqueous emulsion with Fluoxastrobin
Embodiment 29：22% aloe-emodin azoxystrobin water emulsion
Aloe-emodin 20%, Fluoxastrobin 2%, remaining component is prepared according to the method for embodiment 17.
Embodiment 30：22% aloe-emodin azoxystrobin water emulsion
Aloe-emodin 2%, Fluoxastrobin 20%, remaining component is prepared according to the method for embodiment 18.
(8) active component A (aloe-emodin) prepares aqueous emulsion with fluoxastrobin
Embodiment 31：22% aloe-emodin fluoxastrobin aqueous emulsion
Aloe-emodin 20%, fluoxastrobin 2%, remaining component is prepared according to the method for embodiment 17.
Embodiment 32：22% aloe-emodin fluoxastrobin aqueous emulsion
Aloe-emodin 2%, fluoxastrobin 20%, remaining component is prepared according to the method for embodiment 18.
(3) processing of wettable powder and embodiment
Active components A and B activity composition and various auxiliary agents and filler etc. are sufficiently mixed in proportion, through ultrafine crusher powder
Prepared wettable powder after broken.
(1) active component A (Physcion) prepares wettable powder with pyraclostrobin
Embodiment 33：41% Physcion pyraclostrobin wettable powder
Physcion 1%, pyraclostrobin 40%, neopelex 3%, sodium lignin sulfonate 5%, diatom
Soil 8%, kaolin complements to 100%.
Embodiment 34：31.5% Physcion pyraclostrobin wettable powder
Physcion 1.5%, pyraclostrobin 30%, pull open powder 3%, bentonite 2%, alkyl polyoxyethanyl ether sulfonic acid
Salt 3%, white carbon 1%, diatomite complements to 100%.
(2) active component A (Physcion) prepares wettable powder with ZEN 90160
Embodiment 35：41% Physcion chlorfenapyr wettable powder
Physcion 1%, ZEN 90160 40%, remaining component is prepared according to the method for embodiment 33.
Embodiment 36：31.5% Physcion chlorfenapyr wettable powder
Physcion 1.5%, ZEN 90160 30%, remaining component is prepared according to the method for embodiment 34.
(3) active component A (Physcion) prepares wettable powder with Fluoxastrobin
Embodiment 37：41% Physcion Fluoxastrobin wettable powder
Physcion 1%, Fluoxastrobin 40%, remaining component is prepared according to the method for embodiment 33.
Embodiment 38：31.5% Physcion Fluoxastrobin wettable powder
Physcion 1.5%, Fluoxastrobin 30%, remaining component is prepared according to the method for embodiment 34.
(4) active component A (Physcion) prepares wettable powder with fluoxastrobin
Embodiment 39：41% Physcion fluoxastrobin wettable powder
Physcion 1%, fluoxastrobin 40%, remaining component is prepared according to the method for embodiment 33.
Embodiment 40：31.5% Physcion fluoxastrobin wettable powder
Physcion 1.5%, fluoxastrobin 30%, remaining component is prepared according to the method for embodiment 34.
(5) active component A (aloe-emodin) prepares wettable powder with pyraclostrobin
Embodiment 41：41% aloe-emodin pyraclostrobin wettable powder
Aloe-emodin 1%, pyraclostrobin 40%, remaining component is prepared according to the method for embodiment 33.
Embodiment 42：31.5% aloe-emodin pyraclostrobin wettable powder
Aloe-emodin 1.5%, pyraclostrobin 30%, remaining component is prepared according to the method for embodiment 34.
(6) active component A (aloe-emodin) prepares wettable powder with ZEN 90160
Embodiment 43：41% aloe-emodin chlorfenapyr wettable powder
Aloe-emodin 1%, ZEN 90160 40%, remaining component is prepared according to the method for embodiment 33.
Embodiment 44：31.5% aloe-emodin chlorfenapyr wettable powder
Aloe-emodin 1.5%, ZEN 90160 30%, remaining component is prepared according to the method for embodiment 34.
(7) active component A (aloe-emodin) prepares wettable powder with Fluoxastrobin
Embodiment 45：41% aloe-emodin Fluoxastrobin wettable powder
Aloe-emodin 1%, Fluoxastrobin 40%, remaining component is prepared according to the method for embodiment 33.
Embodiment 46：31.5% aloe-emodin Fluoxastrobin wettable powder
Aloe-emodin 1.5%, Fluoxastrobin 30%, remaining component is prepared according to the method for embodiment 34.
(8) active component A (aloe-emodin) prepares wettable powder with fluoxastrobin
Embodiment 47：41% aloe-emodin fluoxastrobin wettable powder
Aloe-emodin 1%, fluoxastrobin 40%, remaining component is prepared according to the method for embodiment 33.
Embodiment 48：31.5% aloe-emodin fluoxastrobin wettable powder
Aloe-emodin 1.5%, fluoxastrobin 30%, remaining component is prepared according to the method for embodiment 34.
(4) processing of microemulsion and embodiment
By active components A and B, it is well mixed in the ratio of formula with solvent, surfactant, stabilizer, water, is obtained afterwards
Microemulsion product.
(1) active component A (Physcion) prepares microemulsion with pyraclostrobin
Embodiment 49：25.5% Physcion pyraclostrobin microemulsion
Physcion 0.5%, pyraclostrobin 25%, dimethyl sulfoxide (DMSO) 12%, methyl naphthalene sulfonate formaldehyde condensate
7%, lauryl sodium sulfate 2%, calcium stearate 4%, water complements to 100%.
Embodiment 50：18.3% Physcion pyraclostrobin microemulsion
Physcion 0.3%, pyraclostrobin 18%, Isopropanediol 15%, detergent alkylate naphthalene sulfonic acids calcium 11%, firmly
Resin acid sodium 5%, water complements to 100%.
(2) active component A (Physcion) prepares microemulsion with ZEN 90160
Embodiment 51：25.5% Physcion ZEN 90160 microemulsion
Physcion 0.5%, ZEN 90160 25%, remaining component is prepared according to the method for embodiment 49.
Embodiment 52：18.3% Physcion ZEN 90160 microemulsion
Physcion 0.3%, ZEN 90160 18%, remaining component is prepared according to the method for embodiment 50.
(3) active component A (Physcion) prepares microemulsion with Fluoxastrobin
Embodiment 53：25.5% Physcion azoxystrobin microemulsion
Physcion 0.5%, Fluoxastrobin 25%, remaining component is prepared according to the method for embodiment 49.
Embodiment 54：18.3% Physcion azoxystrobin microemulsion
Physcion 0.3%, Fluoxastrobin 18%, remaining component is prepared according to the method for embodiment 50.
(4) active component A (Physcion) prepares microemulsion with fluoxastrobin
Embodiment 55：25.5% Physcion fluoxastrobin microemulsion
Physcion 0.5%, fluoxastrobin 25%, remaining component is prepared according to the method for embodiment 49.
Embodiment 56：18.3% Physcion fluoxastrobin microemulsion
Physcion 0.3%, fluoxastrobin 18%, remaining component is prepared according to the method for embodiment 50.
(5) active component A (aloe-emodin) prepares microemulsion with pyraclostrobin
Embodiment 57：25.5% aloe-emodin pyraclostrobin microemulsion
Aloe-emodin 0.5%, pyraclostrobin 25%, remaining component is prepared according to the method for embodiment 49.
Embodiment 58：18.3% aloe-emodin pyraclostrobin microemulsion
Aloe-emodin 0.3%, pyraclostrobin 18%, remaining component is prepared according to the method for embodiment 50.
(6) active component A (aloe-emodin) prepares microemulsion with ZEN 90160
Embodiment 59：25.5% aloe-emodin ZEN 90160 microemulsion
Aloe-emodin 0.5%, ZEN 90160 25%, remaining component is prepared according to the method for embodiment 49.
Embodiment 60：18.3% aloe-emodin ZEN 90160 microemulsion
Aloe-emodin 0.3%, ZEN 90160 18%, remaining component is prepared according to the method for embodiment 50.
(7) active component A (aloe-emodin) prepares microemulsion with Fluoxastrobin
Embodiment 61：25.5% aloe-emodin azoxystrobin microemulsion
Aloe-emodin 0.5%, Fluoxastrobin 25%, remaining component is prepared according to the method for embodiment 49.
Embodiment 62：18.3% aloe-emodin azoxystrobin microemulsion
Aloe-emodin 0.3%, Fluoxastrobin 18%, remaining component is prepared according to the method for embodiment 50.
(8) active component A (aloe-emodin) prepares microemulsion with fluoxastrobin
Embodiment 63：25.5% aloe-emodin fluoxastrobin microemulsion
Aloe-emodin 0.5%, fluoxastrobin 25%, remaining component is prepared according to the method for embodiment 49.
Embodiment 64：18.3% aloe-emodin fluoxastrobin microemulsion
Aloe-emodin 0.3%, fluoxastrobin 18%, remaining component is prepared according to the method for embodiment 50.
(5) processing of water dispersible granules and embodiment
It is well mixed, active component activity packet A and active component B through gas in the ratio of formula with auxiliary agent and filler
Stream is ground into wettable powder, adds a certain amount of water mixing extruder grain, water dispersible granules is obtained after drying screening and produces
Product.
(1) active component A (Physcion) and pyraclostrobin are for water dispersible granules
Embodiment 65：85.2% Physcion pyraclostrobin water dispersible granule
Physcion 1.2%, pyraclostrobin 84%, Arabic gum 2%, bentonite 2%, sodium acid carbonate 3%, polypropylene
Acid amides 2%, white carbon supply to 100%.
Embodiment 66：85.2% Physcion water dispersible granule
Physcion 1.2%, ZEN 90160 84%, remaining component is prepared according to the method for embodiment 65.
Embodiment 67：85.4% Physcion azoxystrobin water dispersible granule
Physcion 1.2%, Fluoxastrobin 84%, remaining component is prepared according to the method for embodiment 65.
Embodiment 68：85.2% Physcion fluoxastrobin water dispersible granules
Physcion 1.4%, fluoxastrobin 84%, remaining component is prepared according to the method for embodiment 65.
Embodiment 69：85.2% aloe-emodin pyraclostrobin water dispersible granule
Aloe-emodin 1.2%, pyraclostrobin 84%, remaining component is prepared according to the method for embodiment 65.
Embodiment 70：85.2% aloe-emodin water dispersible granule
Aloe-emodin 1.2%, ZEN 90160 84%, remaining component is prepared according to the method for embodiment 65.
Embodiment 71：85.2% aloe-emodin azoxystrobin water dispersible granule
Aloe-emodin 1.2%, Fluoxastrobin 84%, remaining component is prepared according to the method for embodiment 65.
Embodiment 72：85.2% aloe-emodin fluoxastrobin water dispersible granules
Aloe-emodin 1.2%, fluoxastrobin 84%, remaining component is prepared according to the method for embodiment 65.
2nd, drug effect checking test
(1) Assays Example
The incidence of whole strain blade is investigated according to experiment grade scale, disease index and prevention effect is calculated.
Prevention effect is converted into niqueMin (y), liquor strength (μ g/ml) is converted into logarithm value (x), with least square method
Concentration EC50 in calculating virulence equation and suppressing, the toxicity index and co-toxicity coefficient (CTC) of medicament are calculated according to the abundant methods of Sun Yun.
Actual measurement toxicity index (ATI)=(standard agent EC50/ reagent agent EC50) * 100
Percentage composition+B medicament toxicity index * the mixtures of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixtures
The percentage composition of middle B
Co-toxicity coefficient (CTC)=[mixture surveys toxicity index (ATI)/mixture theoretical toxicity index (TTI)] * 100
CTC≤80, composition shows as antagonism, 80 ＜ CTC ＜ 120, and composition shows as summation action, and CTC >=
120, composition shows as synergistic effect.
1st, Physcion and pyraclostrobin compounding are tested pepper powdery mildew toxicity test
The Physcion of table 1. is compounded to pepper powdery mildew toxicity test interpretation of result with pyraclostrobin
As a result (table 1) show, in Physcion：Pyraclostrobin=1:In 1~70 interval range, Physcion with
Pyraclostrobin compounds and the prevention effect of pepper powdery mildew is significantly improved, and illustrates that the two compounding has aobvious to pepper powdery mildew preventing and treating
The synergistic effect of work.And outside above protection domain, both then show the effect of addition.
2nd, Physcion and ZEN 90160 compounding are tested cauliflower downy mildew toxicity test
The Physcion of table 2. is compounded to cauliflower downy mildew toxicity test interpretation of result with ZEN 90160
| Medicament title | EC50(ug/mL) | ATI | TTI | CTC |
| Physcion | 1.70 | 100.00 | \ | \ |
| ZEN 90160 | 16.31 | 10.42 | \ | \ |
| Physcion：ZEN 90160=1:80 | 12.55 | 13.55 | 11.53 | 117.57 |
| Physcion：ZEN 90160=1:70 | 11.51 | 14.77 | 11.68 | 126.40 |
| Physcion：ZEN 90160=1:60 | 10.84 | 15.68 | 11.89 | 131.89 |
| Physcion：ZEN 90160=1:50 | 10.23 | 16.61 | 12.18 | 136.44 |
| Physcion：ZEN 90160=1:40 | 9.68 | 17.56 | 12.60 | 139.33 |
| Physcion：ZEN 90160=1:30 | 8.90 | 19.10 | 13.31 | 143.54 |
| Physcion：ZEN 90160=1:20 | 7.52 | 22.60 | 14.69 | 153.90 |
| Physcion：ZEN 90160=1:10 | 6.56 | 25.91 | 18.56 | 139.57 |
| Physcion：ZEN 90160=1:1 | 2.33 | 72.91 | 55.21 | 132.06 |
| Physcion：ZEN 90160=1:0.1 | 1.47 | 115.56 | 91.86 | 125.81 |
| Physcion：ZEN 90160=1:0.05 | 1.48 | 114.99 | 95.73 | 120.11 |
As a result (table 2) show, in Physcion：ZEN 90160=1:In 0.1~70 interval range, Physcion with
ZEN 90160 compounds and the prevention effect of cauliflower downy mildew is significantly improved, and illustrates that the two compounding has to the preventing and treating of cauliflower downy mildew
Significant synergistic effect.And outside above protection domain, both then show the effect of addition.
3rd, Physcion and azoxystrobin compound are tested Hemintho-sporum leaf spot of rice plants toxicity test
The Physcion of table 3. is with azoxystrobin compound to Hemintho-sporum leaf spot of rice plants toxicity test interpretation of result
As a result (table 3) show, in Physcion：Fluoxastrobin=1:In 0.1~70 interval range, Physcion with it is phonetic
Bacterium ester compounds and the prevention effect of Hemintho-sporum leaf spot of rice plants is significantly improved, and illustrates that the two compounding has significantly to Hemintho-sporum leaf spot of rice plants preventing and treating
Synergistic effect.And outside above protection domain, both then show the effect of addition.
4th, Physcion and fluoxastrobin compounding are tested eggplant bacterial wilt toxicity test
The Physcion of table 4. is compounded to eggplant bacterial wilt toxicity test interpretation of result with fluoxastrobin
| Medicament title | EC50(ug/mL) | ATI | TTI | CTC |
| Physcion | 2.41 | 100.00 | \ | \ |
| Fluoxastrobin | 15.14 | 15.92 | \ | \ |
| Physcion：Fluoxastrobin=1:80 | 12.98 | 18.57 | 16.96 | 109.53 |
| Physcion：Fluoxastrobin=1:70 | 11.34 | 21.26 | 17.10 | 124.30 |
| Physcion：Fluoxastrobin=1:60 | 10.65 | 22.64 | 17.30 | 130.88 |
| Physcion：Fluoxastrobin=1:50 | 10.17 | 23.70 | 17.57 | 134.90 |
| Physcion：Fluoxastrobin=1:40 | 9.77 | 24.67 | 17.97 | 137.27 |
| Physcion：Fluoxastrobin=1:30 | 9.01 | 26.75 | 18.63 | 143.58 |
| Physcion：Fluoxastrobin=1:20 | 7.82 | 30.83 | 19.92 | 154.72 |
| Physcion：Fluoxastrobin=1:10 | 6.89 | 34.97 | 23.56 | 148.41 |
| Physcion：Fluoxastrobin=1:1 | 3.34 | 72.25 | 57.96 | 124.66 |
| Physcion：Fluoxastrobin=1:0.1 | 2.15 | 112.20 | 92.36 | 121.49 |
| Physcion：Fluoxastrobin=1:0.05 | 2.19 | 110.21 | 96.00 | 114.81 |
As a result (table 4) show, in Physcion：Fluoxastrobin=1:In 0.1~70 interval range, Physcion with
Fluoxastrobin compounds and the prevention effect of eggplant bacterial wilt is significantly improved, and illustrates that the two compounding has significantly to the preventing and treating of eggplant bacterial wilt
Synergistic effect.And outside above protection domain, both then show the effect of addition.
5th, aloe-emodin and pyraclostrobin compounding are tested garlic leaf blight toxicity test
The aloe-emodin of table 5. is compounded to garlic leaf blight toxicity test interpretation of result with pyraclostrobin
| Medicament title | EC50(ug/mL) | ATI | TTI | CTC |
| Aloe-emodin | 1.85 | 100.00 | \ | \ |
| Pyraclostrobin | 17.48 | 10.58 | \ | \ |
| Aloe-emodin：Pyraclostrobin=1:80 | 13.48 | 13.73 | 11.68 | 117.47 |
| Aloe-emodin：Pyraclostrobin=1:70 | 12.60 | 14.68 | 11.84 | 124.00 |
| Aloe-emodin：Pyraclostrobin=1:60 | 11.91 | 15.53 | 12.05 | 128.92 |
| Aloe-emodin：Pyraclostrobin=1:50 | 11.35 | 16.30 | 12.33 | 132.20 |
| Aloe-emodin：Pyraclostrobin=1:40 | 10.53 | 17.57 | 12.76 | 137.66 |
| Aloe-emodin：Pyraclostrobin=1:30 | 9.43 | 19.62 | 13.46 | 145.71 |
| Aloe-emodin：Pyraclostrobin=1:20 | 8.13 | 22.76 | 14.84 | 153.42 |
| Aloe-emodin：Pyraclostrobin=1:10 | 6.51 | 28.42 | 18.71 | 151.90 |
| Aloe-emodin：Pyraclostrobin=1:1 | 2.54 | 72.70 | 55.29 | 131.49 |
| Aloe-emodin：Pyraclostrobin=1:0.1 | 1.61 | 115.04 | 91.87 | 125.22 |
| Aloe-emodin：Pyraclostrobin=1:0.05 | 1.70 | 109.08 | 95.74 | 113.94 |
As a result (table 5) show, in aloe-emodin：Pyraclostrobin=1:In 0.1~70 interval range, aloe-emodin
The prevention effect of garlic leaf blight is significantly improved with pyraclostrobin compounding, illustrates that the two compounding has to garlic leaf blight preventing and treating
Significant synergistic effect.And outside above protection domain, both then show the effect of addition.
6th, aloe-emodin and ZEN 90160 compounding are tested lettuce powdery mildew toxicity test
The aloe-emodin of table 6. is compounded to lettuce powdery mildew toxicity test interpretation of result with ZEN 90160
As a result (table 6) show, in aloe-emodin：ZEN 90160=1:In 0.1~70 interval range, aloe-emodin with
ZEN 90160 compounds and the prevention effect of lettuce powdery mildew is significantly improved, and illustrates that the two compounding has significantly to lettuce controlling powdery mildew
Synergistic effect.And outside above protection domain, both then show the effect of addition.
7th, aloe-emodin and azoxystrobin compound are tested verdant downy mildew toxicity test
The aloe-emodin of table 7. is with azoxystrobin compound to verdant downy mildew toxicity test interpretation of result
| Medicament title | EC50(ug/mL) | ATI | TTI | CTC |
| Aloe-emodin | 1.59 | 100.00 | \ | \ |
| Fluoxastrobin | 15.45 | 10.29 | \ | \ |
| Aloe-emodin：Fluoxastrobin=1:80 | 11.76 | 13.52 | 11.40 | 118.62 |
| Aloe-emodin：Fluoxastrobin=1:70 | 11.02 | 14.43 | 11.55 | 124.91 |
| Aloe-emodin：Fluoxastrobin=1:60 | 10.60 | 15.00 | 11.76 | 127.54 |
| Aloe-emodin：Fluoxastrobin=1:50 | 10.00 | 15.89 | 12.05 | 131.90 |
| Aloe-emodin：Fluoxastrobin=1:40 | 9.23 | 17.22 | 12.48 | 138.02 |
| Aloe-emodin：Fluoxastrobin=1:30 | 8.44 | 18.84 | 13.18 | 142.88 |
| Aloe-emodin：Fluoxastrobin=1:20 | 7.41 | 21.44 | 14.56 | 147.26 |
| Aloe-emodin：Fluoxastrobin=1:10 | 6.22 | 25.58 | 18.45 | 138.69 |
| Aloe-emodin：Fluoxastrobin=1:1 | 2.17 | 73.31 | 55.15 | 132.94 |
| Aloe-emodin：Fluoxastrobin=1:0.1 | 1.38 | 114.83 | 91.84 | 125.03 |
| Aloe-emodin：Fluoxastrobin=1:0.05 | 1.45 | 109.99 | 95.73 | 114.89 |
As a result (table 7) show, in aloe-emodin：Fluoxastrobin=1:In 0.1~70 interval range, aloe-emodin with it is phonetic
Bacterium ester compounds and the prevention effect of verdant downy mildew is significantly improved, and illustrates that the two compounding has significant increasing to the preventing and treating of verdant downy mildew
Effect is acted on.And outside above protection domain, both then show the effect of addition.
8th, aloe-emodin and fluoxastrobin compounding are tested sorghum leaf blight toxicity test
The aloe-emodin of table 8. is compounded to sorghum leaf blight toxicity test interpretation of result with fluoxastrobin
As a result (table 7) show, in aloe-emodin：Fluoxastrobin=1:In 0.1~70 interval range, aloe-emodin with
Fluoxastrobin compounds and the prevention effect of sorghum leaf blight is significantly improved, and illustrates that the two compounding has significantly to the preventing and treating of sorghum leaf blight
Synergistic effect.And outside above protection domain, both then show the effect of addition.
(2) field efficacy checking test
Test method：At the initial stage of a disease, first time spraying is carried out immediately, and second dispenser is carried out after 7 days, each treatment 4
Individual cell, each square meter of cell 20.In 11 days investigation statisticses incidences before medicine and after second medicine, 5 points of each cell is random
Sampling, 5 plants of crops of every investigation, investigates the lesion area in whole strain per blade and accounts for the percentage of blade area and be classified, and calculates
Disease index and prevention effect.
Expected preventive effect (%)=X+Y-XY/100 (wherein, X, Y are single dose preventive effect)
Grade scale：
0 grade：Disease-free spot；
1 grade：Leaf spot lesion is less than 5, and length is less than 1cm；
3 grades：Leaf spot lesion 6-10, part scab length is more than 1cm；
5 grades：Leaf spot lesion 11-25, part scab is linked to be piece, and lesion area accounts for the 10-25% of leaf area；
7 grades：Leaf spot lesion more than 26, scab is linked to be piece, and lesion area accounts for the 26-50% of leaf area；
9 grades：Scab is linked to be piece, and more than 50% or the full leaf that lesion area accounts for leaf area are withered.
1st, Physcion and pyraclostrobin compounding field efficacy experiment
The Chrysophanol of table 9. is with pyraclostrobin mixture to cowpea spot blight prevention effect
Measurement result (table 9) shows that Chrysophanol is significantly improved with the compounding of pyraclostrobin to cowpea spot blight preventive effect, is said
Bright the two compounding has significant synergistic effect to cowpea spot blight.
2nd, Physcion and ZEN 90160 compounding field efficacy experiment
The Chrysophanol of table 10. is with ZEN 90160 mixture to early blight of celery prevention effect
Measurement result (table 10) shows that Physcion is substantially carried with the compounding of ZEN 90160 to early blight of celery preventive effect
Height, illustrates that the two compounding has significant synergistic effect to early blight of celery.
3rd, Physcion and azoxystrobin compound field efficacy are tested
The Physcion of table 11 is with Fluoxastrobin mixture to balsam pear controlling powdery mildew effect
Measurement result (table 11) shows that Physcion is significantly improved with Fluoxastrobin mixture to balsam pear powdery mildew preventive effect,
Illustrate that the two compounding has significant synergistic effect to balsam pear powdery mildew.
4th, Physcion and fluoxastrobin compounding field efficacy experiment
The Physcion of table 12. is with fluoxastrobin mixture to peronophythora litchi prevention effect
Measurement result (table 12) shows that Physcion is substantially carried with fluoxastrobin mixture to peronophythora litchi preventive effect
Height, illustrates that the two compounding has significant synergistic effect to peronophythora litchi.
5th, aloe-emodin and pyraclostrobin compounding field efficacy experiment
The aloe-emodin of table 13. is with pyraclostrobin mixture to ginger anthracnose prevention effect
Measurement result (table 13) shows that aloe-emodin is substantially carried with pyraclostrobin mixture to ginger anthracnose preventive effect
Height, illustrates that the two compounding has significant synergistic effect to ginger anthracnose.
6th, aloe-emodin and ZEN 90160 compounding field efficacy experiment
The aloe-emodin of table 14. is with ZEN 90160 mixture to oat leaf spot prevention effect
Measurement result (table 14) shows that aloe-emodin is significantly improved with ZEN 90160 mixture to oat leaf spot preventive effect,
Illustrate that the two compounding has significant synergistic effect to oat leaf spot.
7th, aloe-emodin and azoxystrobin compound field efficacy are tested
The aloe-emodin of table 15. is with Fluoxastrobin mixture to Kiwi berry Control of Lecanosticta Acicola effect
Measurement result (table 15) shows that aloe-emodin is significantly improved with Fluoxastrobin mixture to macaque peach blight preventive effect,
Illustrate that the two compounding has significant synergistic effect to macaque peach blight.
8th, aloe-emodin and fluoxastrobin compounding field efficacy experiment
The aloe-emodin of table 16. is with fluoxastrobin mixture to mango controlling powdery mildew effect
Measurement result (table 16) shows that aloe-emodin is significantly improved with fluoxastrobin mixture to mango white powder preventive effect, is said
Bright the two compounding has significant synergistic effect to mango powdery mildew.
Claims (9)
1. a kind of composition pesticide, it is characterised in that described composition includes two kinds of active components of A and B, and active component A is anthracene
Quinones, described anthraquinone analog compound is selected from the one kind in Physcion or aloe-emodin, and active component B is first
Epoxide acrylic bactericide, it is phonetic that described methoxy acrylic bactericide is selected from pyraclostrobin, ZEN 90160, fluorine
One kind in bacterium ester or Fluoxastrobin, the weight ratio between two components is 1:0.1~70.
2. composition pesticide according to claim 1, it is characterised in that the weight of the active component A and active component B
Than being 1:1~60.
3. composition pesticide according to claim 1, it is characterised in that the active component A is Physcion, described
Active component B be pyraclostrobin, wherein the weight ratio of Physcion and pyraclostrobin is 1:1~60.
4. the composition pesticide according to any one in claims 1 to 3, it is characterised in that said composition is by active component
The formulation allowed on agricultural chemicals is made with insecticides adjuvant or auxiliary material.
5. composition pesticide according to claim 4, it is characterised in that said composition by 2~85% weight portions activearm
Divide the formulation allowed on insecticides adjuvant or auxiliary material the composition agricultural chemicals with 98~15% weight portions.
6. composition pesticide according to claim 4, it is characterised in that described formulation is suspending agent, aqueous emulsion, wettable
Property pulvis, water dispersible granules or microemulsion.
7. the composition pesticide according to claim 4 or 5, it is characterised in that the insecticides adjuvant or auxiliary material be selected from carrier,
One or more in solvent, dispersant, wetting agent, adhesive, thickener, adhesive, surfactant or fertilizer.
8. the composition pesticide in claims 1 to 3 described in any one agriculture field preventing and treating corps diseases in terms of use
On the way.
9. application according to claim 8, it is characterised in that in terms of agriculture field prevents and treats veterinary antibiotics, cereal disease
Purposes.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106719750A (en) * | 2017-02-22 | 2017-05-31 | 佛山市瑞生通科技有限公司 | A kind of bactericidal composition of pyraclostrobin-containing and Physcion |
| CN109938045A (en) * | 2019-02-27 | 2019-06-28 | 江苏辉丰生物农业股份有限公司 | Composition pesticide containing toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Physcion |
| CN113016817A (en) * | 2021-04-22 | 2021-06-25 | 中国农业科学院烟草研究所 | Bactericidal composition for preventing and treating powdery mildew of tobacco and preparation method thereof |
| CN113349202A (en) * | 2021-07-13 | 2021-09-07 | 广西壮族自治区亚热带作物研究所（广西亚热带农产品加工研究所） | Biological pesticide for preventing and treating macadamia nut leaf blight |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104957188A (en) * | 2009-07-30 | 2015-10-07 | 马罗内生物创新公司 | Plant pathogen inhibitor combinations and methods of use |
| CN105309489A (en) * | 2014-06-30 | 2016-02-10 | 陕西美邦农药有限公司 | Bactericidal composition containing polygonum cuspidatum extract and pyraclostrobin |
| CN105309494A (en) * | 2014-07-07 | 2016-02-10 | 陕西美邦农药有限公司 | Sterilization composition containing Rhizoma Polygoni Cuspidati extract and fluoxastrobin or picoxystrobin |
| CN105309488A (en) * | 2014-06-25 | 2016-02-10 | 陕西美邦农药有限公司 | Bactericidal composition containing polygonum cuspidatum extract and azoxystrobin or kresoxim-methyl |
| CN106342832A (en) * | 2016-08-29 | 2017-01-25 | 田文华 | Fluoxastrobin and physcion containing sterilization composition |
-
2017
- 2017-01-05 CN CN201710007322.2A patent/CN106719646A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104957188A (en) * | 2009-07-30 | 2015-10-07 | 马罗内生物创新公司 | Plant pathogen inhibitor combinations and methods of use |
| CN105309488A (en) * | 2014-06-25 | 2016-02-10 | 陕西美邦农药有限公司 | Bactericidal composition containing polygonum cuspidatum extract and azoxystrobin or kresoxim-methyl |
| CN105309489A (en) * | 2014-06-30 | 2016-02-10 | 陕西美邦农药有限公司 | Bactericidal composition containing polygonum cuspidatum extract and pyraclostrobin |
| CN105309494A (en) * | 2014-07-07 | 2016-02-10 | 陕西美邦农药有限公司 | Sterilization composition containing Rhizoma Polygoni Cuspidati extract and fluoxastrobin or picoxystrobin |
| CN106342832A (en) * | 2016-08-29 | 2017-01-25 | 田文华 | Fluoxastrobin and physcion containing sterilization composition |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106719750A (en) * | 2017-02-22 | 2017-05-31 | 佛山市瑞生通科技有限公司 | A kind of bactericidal composition of pyraclostrobin-containing and Physcion |
| CN109938045A (en) * | 2019-02-27 | 2019-06-28 | 江苏辉丰生物农业股份有限公司 | Composition pesticide containing toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Physcion |
| CN113016817A (en) * | 2021-04-22 | 2021-06-25 | 中国农业科学院烟草研究所 | Bactericidal composition for preventing and treating powdery mildew of tobacco and preparation method thereof |
| CN113349202A (en) * | 2021-07-13 | 2021-09-07 | 广西壮族自治区亚热带作物研究所（广西亚热带农产品加工研究所） | Biological pesticide for preventing and treating macadamia nut leaf blight |
| CN113349202B (en) * | 2021-07-13 | 2022-04-08 | 广西壮族自治区亚热带作物研究所（广西亚热带农产品加工研究所） | Biological pesticide for preventing and treating macadamia nut leaf blight |
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