CN107753998A - A kind of feminine hygiene articles of bacteriostatic and disease prevention and preparation method thereof - Google Patents
A kind of feminine hygiene articles of bacteriostatic and disease prevention and preparation method thereof Download PDFInfo
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- CN107753998A CN107753998A CN201711260699.5A CN201711260699A CN107753998A CN 107753998 A CN107753998 A CN 107753998A CN 201711260699 A CN201711260699 A CN 201711260699A CN 107753998 A CN107753998 A CN 107753998A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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- Life Sciences & Earth Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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Abstract
The present invention relates to a kind of feminine hygiene articles of bacteriostatic and disease prevention, including the base fabric of bacteriostatic and disease prevention decoction is adsorbed；The decoction includes the active component of following parts by weight：30~60 parts of atractylodes chinensis, 10~20 parts of folium eucalypti extract, 10~20 parts of peppermint leaf extract, 20~40 parts of Rhizoma Chuanxiong extract, 20~40 parts of phellodendron extract.Invention also provides the preparation method of the feminine hygiene articles.The present invention has significant bacteriostatic and disease prevention effect, and product, after long-time is placed, antimicrobial stability is good, has good market popularization value.
Description
Technical field
The present invention relates to female article field, and in particular to a kind of feminine hygiene articles of bacteriostatic and disease prevention and its preparation side
Method.
Background technology
Women goes to toilet, and substitutes toilet paper with napkin, is easy to cause infection, is allowed to suffer from urethral system infection, bacillary, mould
The diseases such as property, trichomonas vaginitis and nonspecific vaginitis.These diseases are that the common disease of women, frequently-occurring disease are because of private parts
Caused by unclean, so, pudendum cleaning is kept to ensureing that body of women health is very critically important, especially before menstrual period or sexual intercourse
Afterwards, it is even more important.
Patent document CN102697671A discloses a kind of liquid medicine for wet tissue of bacteriostatic and disease prevention and preparation method thereof, the wet tissue medicine
The active component of water contains the composition of following parts by weight：Atractylis oil 0.1-5 parts, jamaicin 0.01-0.5 parts, eucalyptus oil 0.01-
0.5 part, borneol 0.01-0.05 parts, menthol 0.01-0.5 parts.With the patent similarly, existing feminine hygiene articles are most
Number is concerned only with prevention or therapeutic effect in itself, and the long-term stability concern for product is less, causes to promote in actual market
Aspect has certain difficulty.
The content of the invention
A kind of it is an object of the present invention to the defects of overcoming prior art, there is provided feminine hygiene articles of bacteriostatic and disease prevention.
Due to having adsorbed decoction in amenities base fabric provided by the invention, and contain complicated active component in medicine company,
On the premise of without using preservative it is long-term place after it is easily rotten, cause effect to decline.The present invention is by atractylodes chinensis, folium eucalypti
Extract, peppermint leaf extract, Rhizoma Chuanxiong extract and phellodendron extract share in the proper ratio, except dry with heat-clearing
It is wet, prevent outside the health-care effect of microorganism infection, the present invention be found surprisingly that said medicine extract combination use, through putting for a long time
Postpone and still be able to play good bacteriostasis efficacy.
Specifically, feminine hygiene articles provided by the invention include the base fabric for having adsorbed bacteriostatic and disease prevention decoction；The medicine
Liquid includes the active component of following parts by weight：30~60 parts of atractylodes chinensis, 10~20 parts of folium eucalypti extract, peppermint leaf extract
10~20 parts, 20~40 parts of Rhizoma Chuanxiong extract, 20~40 parts of phellodendron extract.
Preferably, 55~60 parts of atractylodes chinensis, 10~15 parts of folium eucalypti extract, 15~20 parts of peppermint leaf extract, river
25~30 parts of rhizome of chuanxiong extract, 30~35 parts of phellodendron extract.
The present invention is preferred by being carried out to the extracting method of each extract, can not only improve the concentration of principle active component
So as to improve therapeutic effect, while make to have in medicinal material other compositions of auxiliary effect to be fully extracted, with other medicinal materials into
Divide and play synergy together, make products obtained therefrom that there is good long-acting bacteriostatic effect.Specifically：
The extracting method of the atractylodes chinensis is as follows：Rhizoma atractylodis are taken, are sieved after drying and crushing, carry out CO2Supercritical extract,
Extract 2~5 hours, produce at 20~30MPa of pressure, 35~45 DEG C of temperature.
The extracting method of the folium eucalypti extract is as follows：Folium eucalypti medicinal material is taken, after soaking, steam distillation extraction 1~
5h, filtering, impurity is removed, is produced.
The extracting method of the peppermint leaf extract is as follows：Dried peppermint leaf medicinal material is taken, carries out CO2Supercritical extract, in pressure
Extract 2~5 hours, produce at 20~30MPa, 35~45 DEG C of temperature.
The extracting method of the Rhizoma Chuanxiong extract is as follows：Ligusticum chuanxiong Hort is taken, after soaking, steam distillation extraction 1~
5h, filtering, impurity is removed, is produced.
The extracting method of the phellodendron extract is as follows：Golden cypress medicinal material is taken, 2~5 are extracted with 70~80% alcohol reflux
It is secondary, 1~3h is extracted every time, is merged extract solution, is condensed into medicinal extract, produces.
Decoction of the present invention is using ethanol water, water, propane diols or glycerine as solvent, the use of preferably described solvent
Measure as 200~900 parts by weight.
Odor additive is can further include in the decoction；The odor additive includes pure natural spice or people
Work spices.Wherein：
One or more of the pure natural spice in elscholtiza, borneol, oriental wormwood, peppermint, yellow wormwood artemisia；The artificial flavors
Including plants essential oil and chemical synthesis essence；The plants essential oil is selected from Chinese torreya essential oil, mother chrysanthemum flower essential oil, daphne odera essential oil, pine
One or more in ball essential oil, mugwort oil, thyme essential oil, eucalyptus quintessence oil, tea tree ethereal oil and camphor tree essential oil.
Amenities provided by the invention can be specially sanitary napkin, adult diaper, protection pad, wet wipes or dry wipe.
The base fabric is selected from non-woven fabrics or wet-strength paper.Before adhering liquid medicine, the base fabric first carry out it is suitably sized, so
After carry out sterilization treatment.
Invention also provides a kind of method for the feminine hygiene articles for preparing bacteriostatic and disease prevention, comprise the following steps：
(1) 30~60 parts of atractylodes chinensis, 10~20 parts of folium eucalypti extract, 10~20 parts of peppermint leaf extract, Ligusticum wallichii carries
Take 20~40 parts of thing, 20~40 parts of phellodendron extract is standby；
(2) each component in step (1) is dissolved in solvent, stirred, filtered and remove deposit, take supernatant, mended
Solubilizer is to solvent total amount of adding to 500~900 parts；Or added again after further addition perfume additive in the supernatant
Solvent produces bacteriostatic and disease prevention decoction to solvent total amount of adding to 500~900 parts；
(3) the bacteriostatic and disease prevention decoction is attached in base fabric.
When institute's feminine hygiene articles of the present invention are sanitary napkin, protection pad or adult diaper, the step (3) is specific
For：By the bacteriostatic and disease prevention medicine liquid spray in base fabric, after drying, the top layer as sanitary napkin, protection pad or adult diaper.It is described
Spray makes the base fabric reach water suction saturation by decoction is defined.
When institute's feminine hygiene articles of the present invention are wet wipes, the step (3) is specially：With described antibacterial anti-
Sick decoction infiltrates base fabric, you can.In actual applications, the wet wipes should be independent packaging, to ensure using health.
When institute's feminine hygiene articles of the present invention are dry wipe, the step (3) is specially：Will be described antibacterial anti-
Sick medicine liquid spray is in base fabric, drying, you can.It is described sprinkling by decoction make the base fabric reach water suction saturation be defined.
The feminine hygiene articles of bacteriostatic and disease prevention provided by the invention can suppress bacteria breed, caused by prevention private parts is unclean
Various gynecological diseases, stability is good, has long-acting bacteriostatic, has extensive market application value.
Embodiment
Following examples are used to illustrate the present invention, but are not limited to the scope of the present invention.
In following embodiment：
The extracting method of the atractylodes chinensis is as follows：Rhizoma atractylodis are taken, are sieved after drying and crushing, carry out CO2Supercritical extract,
Extract 3 hours, produce at pressure 25MPa, 40 DEG C of temperature.
The extracting method of the folium eucalypti extract is as follows：Folium eucalypti medicinal material is taken, after soaking, steam distillation extraction 3h,
Filtering, impurity is removed, is produced.
The extracting method of the peppermint leaf extract is as follows：Dried peppermint leaf medicinal material is taken, carries out CO2Supercritical extract, in pressure
Extract 3 hours, produce at 25MPa, 40 DEG C of temperature.
The extracting method of the Rhizoma Chuanxiong extract is as follows：Ligusticum chuanxiong Hort is taken, after soaking, steam distillation extraction 3h,
Filtering, impurity is removed, is produced.
The extracting method of the phellodendron extract is as follows：Take golden cypress medicinal material, with 75% alcohol reflux extract 3 times, every time
2h is extracted, merges extract solution, is condensed into medicinal extract, produces.
Embodiment 1
A kind of sanitary napkin of bacteriostatic and disease prevention is present embodiments provided, is prepared by the following method：
(1) atractylodes chinensis 57kg, folium eucalypti extract 13kg, peppermint leaf extract 18kg, Rhizoma Chuanxiong extract 27kg are taken, it is yellow
Cypress extract 32kg, it is standby；
(2) each component in step (1) is dissolved in solvent, stirred, filtered and remove deposit, take supernatant, mended
Solubilizer is to solvent total amount of adding to 700kg；
(3) by the bacteriostatic and disease prevention medicine liquid spray in base fabric, after drying, the top layer as sanitary napkin.
Embodiment 2
A kind of sanitary napkin of bacteriostatic and disease prevention is present embodiments provided, is prepared by the following method：
(1) atractylodes chinensis 60kg, folium eucalypti extract 15kg, peppermint leaf extract 20kg, Rhizoma Chuanxiong extract 30kg are taken, it is yellow
Cypress extract 35kg, it is standby；
(2) each component in step (1) is dissolved in solvent, stirred, filtered and remove deposit, take supernatant, mended
Solubilizer is to solvent total amount of adding to 500kg；
(3) by the bacteriostatic and disease prevention medicine liquid spray in base fabric, after drying, the top layer as sanitary napkin.
Embodiment 3
A kind of sanitary napkin of bacteriostatic and disease prevention is present embodiments provided, is prepared by the following method：
(1) atractylodes chinensis 55kg, folium eucalypti extract 10kg, peppermint leaf extract 15kg, Rhizoma Chuanxiong extract 25kg are taken, it is yellow
Cypress extract 30kg, it is standby；
(2) each component in step (1) is dissolved in solvent, stirred, filtered and remove deposit, take supernatant, mended
Solubilizer is to solvent total amount of adding to 900kg；
(3) by the bacteriostatic and disease prevention medicine liquid spray in base fabric, after drying, the top layer as sanitary napkin.
Embodiment 4
A kind of sanitary napkin of bacteriostatic and disease prevention is present embodiments provided, is prepared by the following method：
(1) atractylodes chinensis 30kg, folium eucalypti extract 10kg, peppermint leaf extract 10kg, Rhizoma Chuanxiong extract 20kg are taken, it is yellow
Cypress extract 20kg, it is standby；
(2) each component in step (1) is dissolved in solvent, stirred, filtered and remove deposit, take supernatant, mended
Solubilizer is to solvent total amount of adding to 500kg；
(3) by the bacteriostatic and disease prevention medicine liquid spray in base fabric, after drying, the top layer as sanitary napkin.
Embodiment 5
A kind of sanitary napkin of bacteriostatic and disease prevention is present embodiments provided, is prepared by the following method：
(1) atractylodes chinensis 60kg, folium eucalypti extract 20kg, peppermint leaf extract 20kg, Rhizoma Chuanxiong extract 40kg are taken, it is yellow
Cypress extract 40kg, it is standby；
(2) each component in step (1) is dissolved in solvent, stirred, filtered and remove deposit, take supernatant, mended
Solubilizer is to solvent total amount of adding to 900kg；
(3) by the bacteriostatic and disease prevention medicine liquid spray in base fabric, after drying, the top layer as sanitary napkin.
Embodiment 6
A kind of wet wipes of bacteriostatic and disease prevention are present embodiments provided, compared with Example 1, are differed only in：The step
Suddenly (3) are specially：Base fabric, every cloth for cleaning independent packaging are infiltrated with the bacteriostatic and disease prevention decoction, you can.
Embodiment 7
A kind of dry wipe of bacteriostatic and disease prevention is present embodiments provided, compared with Example 1, is differed only in：The step
Suddenly (3) are specially：By the bacteriostatic and disease prevention medicine liquid spray in base fabric, drying, you can.
Comparative example 1
Compared with Example 1, differ only in：The phellodendron extract is replaced with commercially available jamaicin.
Comparative example 2
Compared with Example 1, differ only in, the formula referenced patent document CN102697671A embodiments 2 of liquid medicine are public
The formula opened, is specifically comprised：Atractylis oil 19g, jamaicin 0.5g, eucalyptus oil 0.8g, borneol 0.13g, menthol 1.5g.(close
Count 21.93g)
Preparation method：
1) each composition is weighed according to proportioning, it is standby；
2) Atractylis oil for weighing formula ratio (prepares) 19g according to the method for embodiment 1, is dissolved in 500g 95% ethanol,
Fully after dissolving, bottom white insoluble liq is removed with separatory funnel, the export of upper strata alcoholic solution, obtains rhizoma atractylodis oleyl alcohol, it is standby
With；
3) peppermint, borneol are well mixed, are separately added into jamaicin, rhizoma atractylodis oleyl alcohol, eucalyptus oil and 2500g glycerine,
Well mixed, the ethanol constant volume for adding 95% arrives 10kg, and ultrasonic wave dissolves, to pink colour clear solution, produced.
Experimental example：Long-acting bacteriostatic is tested
After the sanitary napkin that embodiment 1~5 and comparative example 1~2 are provided is placed 0,5,10 month at normal temperatures respectively, test
Bacteriostasis rate, blank control are undressed blank sterilizing non-woven fabrics.Experimental strain：Staphylococcus aureus, Candida albicans,
Escherichia coli, Pseudomonas aeruginosa, hemolytic streptococcus；Specific experiment step refers to《15979-2002 disposable sanitary articles health
Standard》Regulation.As a result as shown in table 1~3.
Table 1：0 month bacteriostasis rate (%)
| Staphylococcus aureus | Candida albicans | Escherichia coli | Pseudomonas aeruginosa | Hemolytic streptococcus | |
| Blank control | 0 | 0 | 0 | 0 | 0 |
| Embodiment 1 | 99.1 | 98.7 | 99.8 | 99.2 | 98.8 |
| Embodiment 2 | 98.9 | 99.2 | 99.1 | 99.5 | 99.0 |
| Embodiment 3 | 99.2 | 98.9 | 98.7 | 98.5 | 99.0 |
| Embodiment 4 | 98.4 | 97.9 | 98.1 | 98.1 | 98.3 |
| Embodiment 5 | 98.5 | 98.7 | 97.9 | 98.8 | 99.0 |
| Comparative example 1 | 97.9 | 98.0 | 98.2 | 98.5 | 97.6 |
| Comparative example 2 | 97.6 | 98.0 | 97.2 | 98.1 | 98.2 |
Table 2：5 months bacteriostasis rates (%)
| Staphylococcus aureus | Candida albicans | Escherichia coli | Pseudomonas aeruginosa | Hemolytic streptococcus | |
| Blank control | 0 | 0 | 0 | 0 | 0 |
| Embodiment 1 | 98.2 | 97.7 | 98.0 | 98.1 | 97.9 |
| Embodiment 2 | 97.4 | 98.4 | 98.5 | 97.9 | 98.2 |
| Embodiment 3 | 98.2 | 97.9 | 97.3 | 97.7 | 98.2 |
| Embodiment 4 | 96.8 | 96.1 | 95.7 | 96.2 | 97.7 |
| Embodiment 5 | 97.1 | 97.2 | 96.9 | 97.3 | 95.8 |
| Comparative example 1 | 92.3 | 94.4 | 93.9 | 94.6 | 93.8 |
| Comparative example 2 | 95.8 | 95.1 | 94.9 | 94.3 | 94.0 |
Table 3：10 months bacteriostasis rates (%)
From result above, product provided by the invention has good fungistatic effect, and is being not added with preservative
In the case of through long-term biocidal property of placing keep stable.
Although above the present invention is made to retouch in detail with general explanation, embodiment and experiment
State, but on the basis of the present invention, it can be made some modifications or improvements, this is apparent to those skilled in the art
's.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, are belonged to claimed
Scope.
Claims (10)
- A kind of 1. feminine hygiene articles of bacteriostatic and disease prevention, it is characterised in that the base fabric including having adsorbed bacteriostatic and disease prevention decoction；It is described Decoction includes the active component of following parts by weight：30~60 parts of atractylodes chinensis, 10~20 parts of folium eucalypti extract, dried peppermint leaf extraction 10~20 parts of thing, 20~40 parts of Rhizoma Chuanxiong extract, 20~40 parts of phellodendron extract.
- 2. feminine hygiene articles according to claim 1, it is characterised in that the decoction includes the activity of following parts by weight Composition：55~60 parts of atractylodes chinensis, 10~15 parts of folium eucalypti extract, 15~20 parts of peppermint leaf extract, Rhizoma Chuanxiong extract 25 ~30 parts, 30~35 parts of phellodendron extract.
- 3. feminine hygiene articles according to claim 1 or 2, it is characterised in that the extracting method of the atractylodes chinensis It is as follows：Rhizoma atractylodis are taken, are sieved after drying and crushing, carry out CO2Supercritical extract, extract at 20~30MPa of pressure, 35~45 DEG C of temperature Take 2~5 hours, produce；And/or：The extracting method of the folium eucalypti extract is as follows：Folium eucalypti medicinal material is taken, after soaking, steam distillation extracts 1~5h, mistake Filter, impurity is removed, is produced；And/or：The extracting method of the peppermint leaf extract is as follows：Dried peppermint leaf medicinal material is taken, carries out CO2Supercritical extract, pressure 20~ Extract 2~5 hours, produce at 30MPa, 35~45 DEG C of temperature；And/or：The extracting method of the Rhizoma Chuanxiong extract is as follows：Ligusticum chuanxiong Hort is taken, after soaking, steam distillation extracts 1~5h, mistake Filter, impurity is removed, is produced；And/or：The extracting method of the phellodendron extract is as follows：Take golden cypress medicinal material, with 70~80% alcohol reflux extract 2~5 times, often 1~3h of secondary extraction, merge extract solution, be condensed into medicinal extract, produce.
- 4. according to the feminine hygiene articles described in claims 1 to 3 any one, it is characterised in that the decoction is with ethanol water As solvent, the dosage of preferably described solvent is 200~900 parts by weight for solution, water, propane diols or glycerine.
- 5. according to the feminine hygiene articles described in Claims 1 to 4 any one, it is characterised in that also include in the decoction Odor additive；The odor additive includes pure natural spice or artificial flavors.
- 6. feminine hygiene articles according to claim 5, it is characterised in that the pure natural spice be selected from elscholtiza, borneol, One or more in oriental wormwood, peppermint, yellow wormwood artemisia；The artificial flavors include plants essential oil and chemical synthesis essence；The plant Essential oil be selected from Chinese torreya essential oil, mother chrysanthemum flower essential oil, daphne odera essential oil, pinecone essential oil, mugwort oil, thyme essential oil, eucalyptus quintessence oil, One or more in tea tree ethereal oil and camphor tree essential oil.
- 7. according to the feminine hygiene articles described in claim 1~6 any one, it is characterised in that the amenities is to defend Raw towel, adult diaper, protection pad, wet wipes or dry wipe.
- 8. feminine hygiene articles according to claim 7, it is characterised in that the base fabric is selected from non-woven fabrics or wet-strength paper.
- A kind of 9. method for the feminine hygiene articles for preparing bacteriostatic and disease prevention, it is characterised in that comprise the following steps：(1) 30~60 parts of atractylodes chinensis, 10~20 parts of folium eucalypti extract, 10~20 parts of peppermint leaf extract, Rhizoma Chuanxiong extract 20~40 parts, 20~40 parts of phellodendron extract is standby；(2) each component in step (1) is dissolved in solvent, stirred, filtered and remove deposit, take supernatant, add molten Agent is to solvent total amount of adding to 500~900 parts；Or solvent is added again after further addition perfume additive in the supernatant To solvent total amount of adding to 500~900 parts, bacteriostatic and disease prevention decoction is produced；(3) the bacteriostatic and disease prevention decoction is attached in base fabric.
- 10. according to the method for claim 9, it is characterised in that when the feminine hygiene articles be sanitary napkin, protection pad or into During people's diaper, the step (3) is specially：By the bacteriostatic and disease prevention medicine liquid spray in base fabric, after drying, as sanitary napkin, The top layer of protection pad or adult diaper；When the feminine hygiene articles are wet wipes, the step (3) is specially：Base is infiltrated with the bacteriostatic and disease prevention decoction Cloth, you can；When the feminine hygiene articles are dry wipe, the step (3) is specially：The bacteriostatic and disease prevention medicine liquid spray is existed In base fabric, drying, you can.
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| CN108273118A (en) * | 2018-03-15 | 2018-07-13 | 广西中医药大学 | Chinese medicine antibacterial sanitary napkin containing graphene oxide-copper silver nanoparticle compound |
| CN108434509A (en) * | 2018-03-15 | 2018-08-24 | 广西中医药大学 | Chinese medicine antibacterial paper diaper detachably containing graphene oxide-copper silver nanoparticle compound |
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| CN108434509A (en) * | 2018-03-15 | 2018-08-24 | 广西中医药大学 | Chinese medicine antibacterial paper diaper detachably containing graphene oxide-copper silver nanoparticle compound |
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Application publication date: 20180306 |