CN102697671A - Bacterium and disease prevention wet wipe liquid medicament and preparation method thereof - Google Patents
Bacterium and disease prevention wet wipe liquid medicament and preparation method thereof Download PDFInfo
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- CN102697671A CN102697671A CN2012101717775A CN201210171777A CN102697671A CN 102697671 A CN102697671 A CN 102697671A CN 2012101717775 A CN2012101717775 A CN 2012101717775A CN 201210171777 A CN201210171777 A CN 201210171777A CN 102697671 A CN102697671 A CN 102697671A
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Abstract
The invention relates to a bacterium and disease prevention wet wipe liquid medicament and a preparation method thereof. The active ingredients of the wet wipe liquid medicament comprise the following components in part by weight: 0.1 to 5 parts of atractylis oil, 0.01 to 0.5 part of berberine, 0.01 to 0.5 part of eucalyptus oil, 0.01 to 0.05 part of borneol, and 0.01 to 0.5 part of menthol. Experiments show that the wet wipe provided by the invention has bacterium and disease prevention functions, no irritation or side effect to skins and vaginal mucosa, aromatic scent, and better effects than the prior art, and is convenient to carry.
Description
Technical field
The present invention relates to the wet tissue field, be specifically related to wet tissue liquid medicine of a kind of bacteriostatic and disease prevention and preparation method thereof.
Background technology
The women goes to toilet, and substitutes toilet paper with napkin, as easy as rolling off a logly causes infection, makes it to suffer from that the urethra system infects, diseases such as bacillary, mycotic, trichomonal vaginitis and nonspecific vaginitis.These diseases be women's commonly encountered diseases, frequently-occurring disease all be because of pudendum unclean due to; So, keep the pudendum cleaning to ensureing that body of women health is very very important, especially menstrual period or sexual intercourse front and back; Even more important, but there is following problem in women's pudendum cleaning supplies:
1) clear water cleans and can only play the single goal of cleaning, and does not have therapeutical effect such as sterilizing and itch-relieving;
2) soap and western medicine solution clean, though certain bactericidal action is arranged, life-time service has zest to skin and mucosa, and be prone to influence the normal PH of vagina, be easy to the breeding of pathogenic bacteria, mycete on the contrary, simultaneously, family uses the concentration that is difficult to grasp medicinal liquid;
3) though the Chinese medicine liquid for cleaning private part does not have untoward reaction such as skin, MMi, when being to use, need certain avoidance place, conditions such as the vessel of subsequent use cleaning, real is inconvenience;
4) finding disinfection wet tissue in the market mostly is hand disinfection before the meal, mainly is to kill gastrointestinal pathogen and hepatitis virus, is not suitable for pudendum and cleans.
One Chinese patent application 200510052052.4 relates to a kind of Rhizoma Atractylodis pharmic paper handkerchief; In paper handkerchief, added pure natural medical production; Thereby suppress growing of antibacterial, acarid, and antibacterial, acaricide, antipruritic are arranged, it can thoroughly kill face mite; To because of acarid and other infect diseases such as the various acne rosacea that cause, acne, acne, obvious curative effects is all arranged.
One Chinese patent application 92113051.1 discloses a kind of be used to the treat pharmaceutical composition of gynaecopathia and the wet tissue of processing with it.This medicine is made up of Fructus Cnidii, Radix Sophorae Flavescentis, Cortex Dictamni, Cortex Phellodendri, Radix Scutellariae, Semen Hydnocarpi, the Radix Stemonae, Pericarpium Granati, Herba Dianthi, Rhizoma Smilacis Glabrae, the Radix Angelicae Dahuricae.This patent compositions focuses on the treatment female gynecological disease, and focus on antipruritic, suitable life-time service, inapplicable to the healthy women of being badly in need of health care.
Existing treatment anal eczema, the medicine of female pelvic inflammation, acute urinary tract infection, pudendum pruritus due to damp pathogen " two wonderful balls " is processed by the powder mixes of Rhizoma Atractylodis and Cortex Phellodendri; Obey every day 2 times; Because the active component utilization rate is low in the medicine,, and there is not the preparation of external so dose is bigger.
Therefore, be badly in need of a kind ofly having bacteriostatic and disease prevention, aromatic refrigerant and comfortable wet tissue, guarantee numerous women's health care demand.
Summary of the invention
The wet tissue liquid medicine that the purpose of this invention is to provide a kind of bacteriostatic and disease prevention.
Another object of the present invention provides the method for preparing of above-mentioned wet tissue liquid medicine.
The wet tissue liquid medicine of a kind of bacteriostatic and disease prevention provided by the invention, its active component contains the composition of following weight portion: Rhizoma Atractylodis oil 0.1-5 part, berberine 0.01-0.5 part, eucalyptus oil 0.01-0.5 part, Borneolum Syntheticum 0.01-0.5 part, Mentholum 0.01-0.5 part.
Preferably, wet tissue liquid medicine provided by the invention, its active component contains the composition of following weight portion: Rhizoma Atractylodis oil 0.5-3 part, berberine 0.01-0.1 part, eucalyptus oil 0.01-0.1 part, Borneolum Syntheticum 0.01-0.3 part, Mentholum 0.1-0.3 part.
Further preferred, wet tissue liquid medicine provided by the invention, its active component contains the composition of following weight portion: 1.9 parts of Rhizoma Atractylodis oils, 0.05 part of berberine, 0.08 part of eucalyptus oil, 0.013 part of Borneolum Syntheticum, 0.15 part of Mentholum.
In the said wet tissue liquid medicine,
Rhizoma Atractylodis oil can be through commercially available acquisition, and also can prepare through following method: Rhizoma Atractylodis are pulverized, and use supercritical extraction, collect volatile oil.
Concrete, Rhizoma Atractylodis oil prepares through following method: Rhizoma Atractylodis are dry, and baking temperature is no more than 60 ℃, pulverize, and cross the 20-40 mesh sieve, carry out CO
2Supercritical extraction is provided with extracting pressure 20-30MPa, and temperature 30-50 ℃, flow speed control extracted 2-5 hour at 20-50L/h, collected volatile oil.
Preferably, Rhizoma Atractylodis oil is prepared by following method: Rhizoma Atractylodis were pulverized 30 mesh sieves, carried out CO
2Supercritical extraction is provided with extracting pressure 25MPa, and 40 ℃ of temperature, flow speed control extracted 4 hours at 30-40L/h, collected volatile oil, promptly got.
Berberine, eucalyptus oil can commercially availablely obtain.
Wet tissue liquid medicine provided by the invention, its adjuvant are glycerol and 80-95% ethanol, wherein the consumption of glycerol be the active component gross weight 50-150 doubly, be preferably 80-130 doubly; Said ethanol is preferably the ethanol of 90-95%.
The present invention provides a kind of method for preparing above-mentioned wet tissue liquid medicine, and this method may further comprise the steps:
1) take by weighing Rhizoma Atractylodis oil, berberine and eucalyptus oil by prescription, subsequent use;
2) the Rhizoma Atractylodis oil mixing is dissolved in the ethanol of 80-95%, makes the Rhizoma Atractylodis oil alcoholic solution;
3) Herba Menthae, Borneolum Syntheticum are mixed, add berberine, Rhizoma Atractylodis oil alcoholic solution, eucalyptus oil and glycerol, mix homogeneously, the ethanol of adding 80-95%, the ultrasound wave dissolving promptly gets.
Preferably, the preparation of said Rhizoma Atractylodis oil alcoholic solution is that the ethanol with Rhizoma Atractylodis oil and 80-95% is 1 according to weight ratio: 10-30 is preferably 1: 15-30 prepares.
The present invention also provides the application of wet tissue liquid medicine in the wet tissue of preparation bacteriostatic and disease prevention.Concrete is is used for wet tissue the women goes to toilet, uses before and after menstrual period or the sexual intercourse, with protection female private part, prophylaxis of gynaecological disorders.
The present invention also provides the method for using of above-mentioned wet tissue liquid medicine, specifically: with the wet tissue liquid medicine dilute with water 1-100 that configures doubly, be preferably 10-50 doubly; Further be preferably 30 times, i.e. the water of 10kg wet tissue liquid medicine and 290kg dilution is sprayed at diluent on the wet tissue carrier again; With napkin moistening degree of being; With the wet tissue packaging seal after moistening, therefrom extract wet tissue during use out again, get final product.
Wet tissue liquid medicine provided by the invention has the following advantages:
1, the Rhizoma Atractylodis oil among the present invention, berberine, eucalyptus oil, Borneolum Syntheticum, five kinds of compositions of Mentholum are united use, have heat clearing and damp drying, eliminating turbid pathogen with aromatics, can prevent infected by microbes to have cleaning, comfortable, health-care effect during use.
2, pharmaceutical composition tool bacteriostat degerming of the present invention effect does not have any zest and side effect to skin and vaginal mucosa, fragrant odour, easy to carry, and effect is superior to prior art.
The specific embodiment
Following examples are used to explain the present invention, but are not used for limiting scope of the present invention.
Embodiment 1: the preparation of Rhizoma Atractylodis oil
Rhizoma Atractylodis are pulverized, and cross 30 mesh sieves, adopt CO
2Supercritical extraction is provided with extracting pressure 25MPa, and 40 ℃ of temperature, flow speed control extracted 4 hours at 30-40L/h, receives once oil per half an hour, until there being volatile oil to come together, and stops extraction, and according to the weight meter, the yield of volatile oil is 5%.
Embodiment 2: wet tissue liquid medicine
1, forms: Rhizoma Atractylodis oil 19g, berberine 0.5g, eucalyptus oil 0.8g, Borneolum Syntheticum 0.13g, Mentholum 1.5g.(adding up to 21.93g)
2, method for preparing:
1) take by weighing each composition according to proportioning, subsequent use;
2) take by weighing Rhizoma Atractylodis oil (according to the preparation of the method for the embodiment 1) 19g of formula ratio, be dissolved in 95% ethanol of 500g, fully after the dissolving, remove bottom white insoluble liq with separatory funnel, the upper strata alcoholic solution is derived, and obtains the Rhizoma Atractylodis oil alcoholic solution, and is subsequent use;
3) with Herba Menthae, Borneolum Syntheticum mix homogeneously, add berberine, Rhizoma Atractylodis oil alcoholic solution, eucalyptus oil and 2500g glycerol respectively, mix homogeneously, the ethanol standardize solution of adding 95% are to 10kg, and the ultrasound wave dissolving to the pink colour clear solution, promptly gets.
Embodiment 3: wet tissue liquid medicine
1, forms: Rhizoma Atractylodis oil 5g, berberine 0.1g, eucalyptus oil 0.1g, Borneolum Syntheticum 0.1g, Mentholum 0.5g.(adding up to 5.8g)
2, method for preparing:
1) take by weighing each composition according to proportioning, subsequent use;
2) take by weighing Rhizoma Atractylodis oil (according to the preparation of the method for the embodiment 1) 5g of formula ratio, be dissolved in 95% ethanol of 150g, fully after the dissolving, remove bottom white insoluble liq with separatory funnel, the upper strata alcoholic solution is derived, and obtains the Rhizoma Atractylodis oil alcoholic solution, and is subsequent use;
3) with Herba Menthae, Borneolum Syntheticum mix homogeneously, add berberine, Rhizoma Atractylodis oil alcoholic solution, eucalyptus oil and 500g glycerol respectively, mix homogeneously, the ethanol standardize solution of adding 95% are to 2kg, and the ultrasound wave dissolving to the pink colour clear solution, promptly gets.
Embodiment 4: wet tissue liquid medicine
1, forms: Rhizoma Atractylodis oil 10g, berberine 1g, eucalyptus oil 3g, Borneolum Syntheticum 3g, Mentholum 1g.(adding up to 18g)
2, method for preparing:
1) take by weighing each composition according to proportioning, subsequent use;
2) take by weighing Rhizoma Atractylodis oil (according to the preparation of the method for the embodiment 1) 10g of formula ratio, be dissolved in 95% ethanol of 100g, fully after the dissolving, remove bottom white insoluble liq with separatory funnel, the upper strata alcoholic solution is derived, and obtains the Rhizoma Atractylodis oil alcoholic solution, and is subsequent use;
3) with Herba Menthae, Borneolum Syntheticum mix homogeneously, add berberine, Rhizoma Atractylodis oil alcoholic solution, eucalyptus oil and 1500g glycerol respectively, mix homogeneously, the ethanol standardize solution of adding 90% are to 6kg, and the ultrasound wave dissolving to the pink colour clear solution, promptly gets.
Embodiment 5: wet tissue liquid medicine
1, forms: Rhizoma Atractylodis oil 10g, berberine 1g, eucalyptus oil 1g, Borneolum Syntheticum 1g, Mentholum 1g.(adding up to 14g)
2, method for preparing:
1) take by weighing each composition according to proportioning, subsequent use;
2) take by weighing Rhizoma Atractylodis oil (according to the preparation of the method for the embodiment 1) 10g of formula ratio, be dissolved in 95% ethanol of 250g, fully after the dissolving, remove bottom white insoluble liq with separatory funnel, the upper strata alcoholic solution is derived, and obtains the Rhizoma Atractylodis oil alcoholic solution, and is subsequent use;
3) with Herba Menthae, Borneolum Syntheticum mix homogeneously, add berberine, Rhizoma Atractylodis oil alcoholic solution, eucalyptus oil and 2100g glycerol respectively, mix homogeneously, the ethanol standardize solution of adding 90% are to 8kg, and the ultrasound wave dissolving to the pink colour clear solution, promptly gets.
Embodiment 6: wet tissue liquid medicine
1, forms: Rhizoma Atractylodis oil 5g, berberine 0.5g, eucalyptus oil 0.5g, Borneolum Syntheticum 0.1g, Mentholum 0.5g (adding up to 6.6g).
2, method for preparing:
1) take by weighing each composition according to proportioning, subsequent use;
2) take by weighing Rhizoma Atractylodis oil (according to the preparation of the method for the embodiment 1) 5g of formula ratio, be dissolved in 95% ethanol of 135g, fully after the dissolving, remove bottom white insoluble liq with separatory funnel, the upper strata alcoholic solution is derived, and obtains the Rhizoma Atractylodis oil alcoholic solution, and is subsequent use;
3) with Herba Menthae, Borneolum Syntheticum mix homogeneously, add berberine, Rhizoma Atractylodis oil alcoholic solution, eucalyptus oil and 330g glycerol respectively, mix homogeneously, the ethanol standardize solution of adding 95% are to 1.3kg, and the ultrasound wave dissolving to the pink colour clear solution, promptly gets.
Experimental example 1: effect experiment
One, selects married woman totally 100 people, be divided into 1 group of 2,3 groups of embodiment and Comparative Examples at random, used for 1 week, its experimental result is added up.Wherein Comparative Examples 1 is formed with reference to " two wonderful balls ", and according to proportioning and the method for preparing preparation of embodiment 2, Rhizoma Atractylodis oil and berberine are processed by 0.7g and 0.03g.
1, the zest to skin, vaginal mucosa influences: the result sees table 1
Table 1: to the zest influence of skin, vaginal mucosa
Table 1 result shows: have 38 routine women to think that product is used for having zest behind the pudendum (account for total number of persons 76%) in the Comparative Examples 1; 2 groups of embodiment are reactionless to have the implementations of stimulation to take place; Only there is 1 women's reaction to have zest among the embodiment 3; The back is introduced according to this women, and she is exactly irritated skin originally.
Prompting: pharmaceutical composition of the present invention is used for wet tissue, and skin and guiding mucosa are not had any zest and side effect, and effect is superior to prior art.
2, the common sensation after the use: see table 2
Table 2: use aftersensation
Table 2 result shows: in the Comparative Examples 1, with the back common sensation relatively real more comfortable 38 examples (38%) are arranged, embodiment 2, embodiment 3 respectively have 78 examples (78%), 80 examples (80%).
Prompting: pharmaceutical composition of the present invention is used for wet tissue, use the back common sensation comfortable, and effect is superior to prior art.
Two, bacteriostatic test:
Select embodiment 2 medicinal liquids, embodiment 3 medicinal liquids, Comparative Examples 1 medicinal liquid (processed by 0.7g and 0.03g by Rhizoma Atractylodis oil and berberine; Method for preparing is with embodiment 2) carry out bacteriostatic experiment operation; Experimentation is: get 8 culture dishs; The medicinal liquid that adds isodose respectively, the culture dish of embodiment 2 herb liquids of packing into is labeled as A, A1; The culture dish of embodiment 3 herb liquids of packing into is labeled as B, B1; The culture dish of the Comparative Examples of packing into 1 herb liquid is labeled as C, C1; The culture dish of distilled water of packing into is labeled as D, D1.
In 8 culture dishs, implant 1 of identical bacterial population respectively, cultivate after three days, it is experimentized.See table 3:
Table 3: bacteriostatic experiment
Table 3 result shows: after cultivating three days through culture dish, A is suitable with the A1 bacterial population, and B is suitable with the B1 bacterial population, and C is suitable with the C1 bacterial population, and D is suitable with the D1 bacterial population.Bacterial population in contrast A (A1), B (B1), C (C1), D (D1) culture dish, discovery: A (A1) is suitable with the middle bacterial population of B (B1), and bacterial population is far smaller than bacterial population among the C (C1) among A (A1), the B (B1), and the middle bacterial population of C (C1) is much smaller than the total bacterial population of D (D1).That is: bacterial population in bacterial population＜blank control group in bacterial population＜Comparative Examples 1 among the bacterial population ≈ embodiment 3 among the embodiment 2.
Prompting: pharmaceutical composition of the present invention has certain bacteriostatic and disease prevention effect, and effect is superior to prior art.
Three, be that other embodiment and other proportionings of the present invention are experimentized simultaneously, find that the effect of effect and embodiment 2 of all the other embodiment is similar.
Four, experiment conclusion: pharmaceutical composition tool bacteriostatic and disease prevention provided by the invention effect, skin and vaginal mucosa there are not any zest and side effect, fragrant odour, easy to carry, effect is superior to prior art.
Experimental example 2: product inspection
Embodiments of the invention have been carried out the observation of color and luster, abnormal smells from the patient, the detection of physical and chemical index and microorganism detection, touchstone is seen table 4.
Table 4: wet tissue touchstone
Wet tissue liquid medicine through the embodiment of the invention is provided is tested, and the wet tissue liquid medicine among the present invention is the transparent emulsus homogeneous of pink colour liquid, does not have deposition and tangible oil droplet; Specify abnormal smells from the patient (Rhzoma Atractylodis Lanceae volatile oil mixing eucalyptus oil abnormal smells from the patient), detect its pH value all within the 6.5-7.8 scope, total number of bacterial colonies in the embodiment of the invention＜100 (cfu/g or cfu/mL), fungus colony sum＜30 (cfu/g or cfu/mL).All not detecting escherichia coli, pathogenic suppuration bacterium, bacteriostasis rate in the embodiments of the invention reaches more than 80%.
Reach a conclusion through assay: pharmaceutical composition provided by the invention is stable and controllable for quality.
Though, used general explanation, the specific embodiment and test in the preceding text, the present invention has been done detailed description, on basis of the present invention, can to some modifications of do or improvement, this will be apparent to those skilled in the art.Therefore, these modifications or the improvement on the basis of not departing from spirit of the present invention, made all belong to the scope that requirement of the present invention is protected.
Claims (10)
1. the wet tissue liquid medicine of a bacteriostatic and disease prevention is characterized in that, its active component contains the composition of following weight portion: Rhizoma Atractylodis oil 0.1-5 part, berberine 0.01-0.5 part, eucalyptus oil 0.01-0.5 part, Borneolum Syntheticum 0.01-0.5 part, Mentholum 0.01-0.5 part.
2. wet tissue liquid medicine according to claim 1 is characterized in that, its active component contains the composition of following weight portion: Rhizoma Atractylodis oil 0.5-3 part, berberine 0.01-0.1 part, eucalyptus oil 0.01-0.1 part, Borneolum Syntheticum 0.01-0.3 part, Mentholum 0.1-0.3 part.
3. wet tissue liquid medicine according to claim 1 is characterized in that, its active component contains the composition of following weight portion: 1.9 parts of Rhizoma Atractylodis oils, 0.05 part of berberine, 0.08 part of eucalyptus oil, 0.013 part of Borneolum Syntheticum, 0.15 part of Mentholum.
4. according to each described wet tissue liquid medicine of claim 1-3, it is characterized in that Rhizoma Atractylodis oil is prepared by following method: Rhizoma Atractylodis are pulverized, and use supercritical extraction, collect volatile oil.
5. wet tissue liquid medicine according to claim 4 is characterized in that, Rhizoma Atractylodis oil prepares through following method: Rhizoma Atractylodis are pulverized, and cross the 20-40 mesh sieve, carry out CO
2Supercritical extraction is provided with extracting pressure 20-30MPa, and temperature 30-50 ℃, flow speed control extracted 2-5 hour at 20-50L/h, collected volatile oil.
6. wet tissue liquid medicine according to claim 5 is characterized in that, Rhizoma Atractylodis oil is prepared by following method: Rhizoma Atractylodis are dry, pulverize 30 mesh sieves, carry out CO
2Supercritical extraction is provided with extracting pressure 25MPa, and 40 ℃ of temperature, flow speed control extracted 4 hours at 30-40L/h, collected volatile oil, promptly got.
7. according to each described wet tissue liquid medicine of claim 1-6, it is characterized in that its adjuvant is the ethanol of glycerol and 80-95%.
8. a method for preparing each described wet tissue liquid medicine of claim 1-7 is characterized in that, this method may further comprise the steps:
1) take by weighing Rhizoma Atractylodis oil, berberine and eucalyptus oil by prescription, subsequent use;
2) the Rhizoma Atractylodis oil mixing is dissolved in the ethanol of 80-95%, makes the Rhizoma Atractylodis oil alcoholic solution;
3) Herba Menthae, Borneolum Syntheticum are mixed, add berberine, Rhizoma Atractylodis oil alcoholic solution, eucalyptus oil and glycerol, mix homogeneously, the ethanol of adding 80-95%, the ultrasound wave dissolving promptly gets.
9. method according to claim 8 is characterized in that, the preparation of said Rhizoma Atractylodis oil alcoholic solution is that the ethanol with Rhizoma Atractylodis oil and 90-95% is 1 according to weight ratio: 10-30 is preferably 1: 15-25 prepares.
10. the application of each described wet tissue liquid medicine of claim 1-7 in the wet tissue of preparation bacteriostatic and disease prevention.
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104524551A (en) * | 2014-12-26 | 2015-04-22 | 上海华新生物高技术有限公司 | Preparation and application of novel interferon alpha-2b wet tissue |
| CN104586972A (en) * | 2014-12-31 | 2015-05-06 | 四川中农致远生物科技有限公司 | Rhizoma coptidis extract solution for prevention and control of mastitis of dairy cattle and preparation method thereof |
| CN107560918A (en) * | 2017-09-22 | 2018-01-09 | 漯河医学高等专科学校 | A kind of pathological tissue specimen fixer |
| CN107754001A (en) * | 2017-12-04 | 2018-03-06 | 株洲千金药业股份有限公司 | A kind of feminine care non-woven fabrics for preventing and treating puerperal infection and its application |
| CN107753998A (en) * | 2017-12-04 | 2018-03-06 | 株洲千金药业股份有限公司 | A kind of feminine hygiene articles of bacteriostatic and disease prevention and preparation method thereof |
| CN107754000A (en) * | 2017-12-04 | 2018-03-06 | 株洲千金药业股份有限公司 | A kind of feminine care non-woven fabrics of bacteriostatic and disease prevention and its application |
| CN107929801A (en) * | 2017-12-04 | 2018-04-20 | 株洲千金药业股份有限公司 | A kind of feminine care non-woven fabrics for preventing menstruation infection and its application |
| CN111576078A (en) * | 2020-05-27 | 2020-08-25 | 龙游旭荣纸业有限公司 | Preparation process and production equipment of antibacterial paper towel |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104524551A (en) * | 2014-12-26 | 2015-04-22 | 上海华新生物高技术有限公司 | Preparation and application of novel interferon alpha-2b wet tissue |
| CN104586972A (en) * | 2014-12-31 | 2015-05-06 | 四川中农致远生物科技有限公司 | Rhizoma coptidis extract solution for prevention and control of mastitis of dairy cattle and preparation method thereof |
| CN107560918A (en) * | 2017-09-22 | 2018-01-09 | 漯河医学高等专科学校 | A kind of pathological tissue specimen fixer |
| CN107754001A (en) * | 2017-12-04 | 2018-03-06 | 株洲千金药业股份有限公司 | A kind of feminine care non-woven fabrics for preventing and treating puerperal infection and its application |
| CN107753998A (en) * | 2017-12-04 | 2018-03-06 | 株洲千金药业股份有限公司 | A kind of feminine hygiene articles of bacteriostatic and disease prevention and preparation method thereof |
| CN107754000A (en) * | 2017-12-04 | 2018-03-06 | 株洲千金药业股份有限公司 | A kind of feminine care non-woven fabrics of bacteriostatic and disease prevention and its application |
| CN107929801A (en) * | 2017-12-04 | 2018-04-20 | 株洲千金药业股份有限公司 | A kind of feminine care non-woven fabrics for preventing menstruation infection and its application |
| CN111576078A (en) * | 2020-05-27 | 2020-08-25 | 龙游旭荣纸业有限公司 | Preparation process and production equipment of antibacterial paper towel |
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| Publication number | Publication date |
|---|---|
| CN102697671B (en) | 2013-12-11 |
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