CN104666594B - It is a kind of to treat tinea pedis moxibustion item and preparation method thereof - Google Patents
It is a kind of to treat tinea pedis moxibustion item and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to technical field of traditional Chinese medicines, specifically disclose it is a kind for the treatment of tinea pedis moxibustion item, also disclose preparation method.The tinea pedis is prepared from the following raw materials in parts by weight with moxibustion item：40 50 parts of folium artemisiae argyi, 20 30 parts of tobacco leaf, 5 10 parts of corter pseudolaricis, 5 10 parts of favus skin, 5 10 parts of the fruit of summer cypress, 5 10 parts of kuh-seng, 5 10 parts of Cortex Phellodendri, 5 10 parts of borneol.Moxibustion monarch compatibility provided by the invention is clear, refining formula, various tinea pedis especially damp heat downward flowing type tinea pedis is treated, with the warm-heat effect of moxa-moxibustion, the efficacy of a drug is made to go directly affected part, it can get rid of evils outgoing, so that cult poison is reached outside with the hot gas of moxa-moxibustion, so that human functional activity of vital energy is orderly and clearly, achievees the effect that heat-clearing and damp-drying drug, desinsection removing toxic substances, dispelling wind and arresting itching, Clinical practice is with obvious effects to tinea pedis treating, and especially treating damp heat downward flowing type tinea pedis has the effect of highly significant.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to and it is a kind of to treat tinea pedis moxibustion item, also relate to its preparation side
Method.
Background technology
Tinea pedis is also referred to as tinea pedis, and for clinical common skin diseases, in China, incidence is higher, accounts for about Dermatology Outpatient Department case
7%-8%.Tinea pedis is that dermatophyte invades the mycotic infection of superficial part disease caused by epidermis, incidence between plantar toe and occupies superficial part
Nosomycosis is the first.The clinical treatment disease mostly uses western medicine at present, that is, passes through external application or oral simple and compound antifungal
It is treated, but still satisfied not to the utmost to fungal bacterial strain kill rate and inhibiting rate, and is also easy to produce drug resistance, late result is not good enough.
Invention content
Treating tinea pedis moxibustion item the object of the present invention is to provide a kind of, can get rid of evils outgoing, make cult poison with the hot gas of moxa-moxibustion and
It reaches outside, so that human functional activity of vital energy is orderly and clearly, achievees the effect that heat-clearing and damp-drying drug, desinsection removing toxic substances, dispelling wind and arresting itching, Clinical practice is to tinea pedis treating
With obvious effects, especially treating damp heat downward flowing type tinea pedis has the effect of highly significant.
The present invention also aims to provide a kind of preparation method for treating tinea pedis moxibustion item.
In order to achieve the goal above, the technical solution adopted in the present invention is：It is a kind of to treat tinea pedis moxibustion item, by following heavy
The raw material of amount number is made：
A kind of preparation method for treating tinea pedis moxibustion item, includes the following steps：
(1) each raw material is weighed by following parts by weight composition：40-50 parts of folium artemisiae argyi, 20-30 parts of tobacco leaf, 5-10 parts of corter pseudolaricis,
5-10 parts of favus skin, 5-10 parts of the fruit of summer cypress, 5-10 parts of kuh-seng, 5-10 parts of Cortex Phellodendri, 5-10 parts of borneol；
(2) it takes corter pseudolaricis, favus skin, the fruit of summer cypress, kuh-seng, Cortex Phellodendri, borneol to be ground into fine powder, sieves with 100 mesh sieve, after sieving
Fine powder mixed with folium artemisiae argyi, tobacco leaf, be made treatment tinea pedis moxibustion item.
Wherein, after corter pseudolaricis, favus skin, the fruit of summer cypress, kuh-seng, Cortex Phellodendri, borneol are ground into fine powder, the Chinese medicine in the fine powder
Particle diameter is no more than 0.15mm.
The treatment tinea pedis is preferably with the specification of moxibustion item：Diameter 18mm, length 200mm, weight 20g.
It is simply described below with the function of each raw material in moxibustion item in treatment tinea pedis provided by the invention：Folium artemisiae argyi, toil, raw temperature
Ripe heat, the property of pure sun can return the exhausted sun that hangs down, and pain 12 passes through, and walk three the moon, and rationale blood expels cold-dampness, with moxibustion fire, can thoroughly all warps and
Except all kinds of diseases and ailments, modern research shows that Chinese mugwort cigarette has antifungic action, main bacteria seed of the Chinese mugwort sootiness to tinea pedis：It is Trichophyton rubrum, cotton-shaped
14 kinds of pathogenic dermatophytes such as Epidermophyton, trichophyton gypseum, toes trichophyta, trichophyton interdigitale have different degrees of
Antibacterial action；Tobacco leaf, pungent-warm is toxic, has the function of removing toxicity for detumescence desinsection, treats favus of the scalp, tinea alba, the disease of the favus of the scalp, is reported according to clinic
Road tobacco leaf is really the outer good medicine for controlling mange, has stronger killing effect to fungi, treats tinea pedis with tobacco leaf, achieved and treated certainly
Effect；Corter pseudolaricis, pungent-warm is toxic, Anti-Puritic and insecticidal, and pharmaceutical research shows corter pseudolaricis as antifungal drug, toxic side effect
It is small, it is less drug resistance occur, especially there are very strong inhibiting effect, electron microscopy study to show to have lethal Trichophyton rubrum；Tinea alba
Skin controls all heat toxin wind, and foul wind, wind sore, mange are red rotten, modern research shows that favus skin is to Trichophyton rubrum, gypsum sample hair tinea
Bacterium, acrothesium floccosum have different degrees of inhibiting effect；The fruit of summer cypress is trembled with fear, and goes bladder hot, pruitus, except heat is very prompt, pharmacology
Studies have shown that supercritical extract summer cypress seed oil to tried bacterium staphylococcus aureus, staphylococcus epidermis, trichophyton gypseum,
The small full daughter bacteria of Trichophyton rubrum, wool has preferable bacteriostatic activity；Kuh-seng, wind-dispelling purging intense heat, the medicine of eliminating dampness worming, modern times grind
Study carefully it has proven convenient that kuh-seng is to the common causative fungi Trichophyton rubrum of tinea pedis, trichophyton gypseum, small armful of daughter bacteria of gypsum sample, cotton-shaped
Epidermophyton, trichophyton tonsurans inhibiting effect are stronger；Cortex Phellodendri, heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment, detumescence are dispelled corruption, under damp and hot
Note type tinea pedis merges localized bacterial infection more, and pharmacological research shows that Cortex Phellodendri not only makees Common fungi with stronger inhibition
With, and have suppression to a variety of pathogenic bacterias such as staphylococcus aureus, staphylococcus albus, hemolytic streptococcus, shigella dysenteriae
It makes and uses；Borneol, bitter, pungent, cool, heat dissipation analgesic, anti-corrosion, modern study carry out antimycotic reality by screening Chinese herbal medicine effective ingredients
Research is tested, borneol has stronger antifungic action.
In treatment tinea pedis provided by the invention in moxibustion item, it is monarch drug in a prescription altogether that folium artemisiae argyi, tobacco leaf, which share, uses it in operation easily
The characteristic of combustion makes heating power act on affected part with Chinese mugwort cigarette, has the function that anti-bacterial, anti-itching；Corter pseudolaricis, favus skin, fruit of summer cypress three close
With for ministerial drug, three have desinsection, removing toxic substances, it is antipruritic the effect of, mixed again with folium artemisiae argyi, tobacco leaf after wearing into fine powder, can more help it
The work(of anti-bacterial, anti-itching；Kuh-seng, Cortex Phellodendri are supplementary drug, the work(for both having heat-clearing and damp-drying drug, desinsection antipruritic, wear into after fine powder with monarch
Medicine, ministerial drug compatibility, can more enhance the efficacy of a drug；Borneol is to make medicine, there is heat dissipation to relieve pain, the work(of antibacterial, is penetrated into after being ground into fine powder
It among all medicines and merges into each other, to make the efficacy of a drug go directly affected part.Moxibustion monarch compatibility provided by the invention is clear, prescription essence
Refining, treats various tinea pedis especially damp heat downward flowing type tinea pedis, with the warm-heat effect of moxa-moxibustion, so that the efficacy of a drug is gone directly affected part, can drive
Heresy is outgoing, and cult poison is made to be reached outside with the hot gas of moxa-moxibustion, so that human functional activity of vital energy is orderly and clearly, reaches heat-clearing and damp-drying drug, desinsection detoxifies, wind-dispelling stops
The effect itched, Clinical practice is with obvious effects to tinea pedis treating, and especially treating damp heat downward flowing type tinea pedis has the treatment of highly significant
Effect.
Specific implementation mode
The technical scheme of the invention is described in detail through specific implementation examples.
Embodiment 1
It is a kind of to treat tinea pedis moxibustion item, it is prepared from the following raw materials in parts by weight：
The treatment tinea pedis preparation method of moxibustion item, includes the following steps：
(1) each raw material is weighed by following parts by weight composition：40 parts of folium artemisiae argyi, 30 parts of tobacco leaf, 5 parts of corter pseudolaricis, favus skin 5
Part, 10 parts of the fruit of summer cypress, 10 parts of kuh-seng, 10 parts of Cortex Phellodendri, 5 parts of borneol；
(2) corter pseudolaricis, favus skin, the fruit of summer cypress, kuh-seng, Cortex Phellodendri, borneol is taken to be ground into fine powder, the Chinese medicinal granule in fine powder is straight
Diameter is no more than 0.15mm, sieves with 100 mesh sieve, the fine powder after sieving is mixed with folium artemisiae argyi, tobacco leaf, and treatment tinea pedis moxibustion item, moxibustion is made
The specification of item is：Diameter 18mm, length 200mm, weight 20g.
Embodiment 2
It is a kind of to treat tinea pedis moxibustion item, it is prepared from the following raw materials in parts by weight：
The treatment tinea pedis preparation method of moxibustion item, includes the following steps：
(1) each raw material is weighed by following parts by weight composition：50 parts of folium artemisiae argyi, 20 parts of tobacco leaf, 10 parts of corter pseudolaricis, favus skin 10
Part, 5 parts of the fruit of summer cypress, 5 parts of kuh-seng, 5 parts of Cortex Phellodendri, 10 parts of borneol；
(2) corter pseudolaricis, favus skin, the fruit of summer cypress, kuh-seng, Cortex Phellodendri, borneol is taken to be ground into fine powder, the Chinese medicinal granule in fine powder is straight
Diameter is no more than 0.15mm, sieves with 100 mesh sieve, the fine powder after sieving is mixed with folium artemisiae argyi, tobacco leaf, and treatment tinea pedis moxibustion item, moxibustion is made
The specification of item is：Diameter 18mm, length 200mm, weight 20g.
Embodiment 3
It is a kind of to treat tinea pedis moxibustion item, it is prepared from the following raw materials in parts by weight：
The treatment tinea pedis preparation method of moxibustion item, includes the following steps：
(1) each raw material is weighed by following parts by weight composition：45 parts of folium artemisiae argyi, 25 parts of tobacco leaf, 8 parts of corter pseudolaricis, favus skin 6
Part, 7 parts of the fruit of summer cypress, 6 parts of kuh-seng, 8 parts of Cortex Phellodendri, 6 parts of borneol；
(2) corter pseudolaricis, favus skin, the fruit of summer cypress, kuh-seng, Cortex Phellodendri, borneol is taken to be ground into fine powder, the Chinese medicinal granule in fine powder is straight
Diameter is no more than 0.15mm, sieves with 100 mesh sieve, the fine powder after sieving is mixed with folium artemisiae argyi, tobacco leaf, and treatment tinea pedis moxibustion item, moxibustion is made
The specification of item is：Diameter 18mm, length 200mm, weight 20g.
The application method for the treatment tinea pedis moxibustion item that embodiment 1-3 is provided：After cleaning affected part, patient takes seat, by foot
It is put on small stool, left hand auxiliary exposure affected part, the right hand holds moxibustion item, moxibustion item is lighted, big centered on affected part away from skin 1-2cm
The range of about 1-2cm carries out convolution moxibustion treatment.Often locate moxibustion 5-10min, feels that part is scorching hot with patient, be resistant to as degree.It is daily early
Each 1 time of evening.1 week as a treatment course.
Clinical effect trial
Test example 1
1, test method
240 tinea pedis patients are chosen, patient is affiliated hospital of Henan Prov. Inst. of Chinese Medicine ＆ Pharmacology Dermatology Outpatient Department patient, is adopted
Patient is divided into four groups by medical sequence with random digits table：Tinea pedis moxibustion item group, western medicine group, pure moxa stick control group, medicine
Moxa stick control group, every group of 60 people of patient.
Tinea pedis moxibustion item group：The treatment tinea pedis moxibustion item provided using the embodiment of the present invention 1；Each moxibustion 1 time daily morning and evening, is controlled
It is 1 week to treat the period.
Western medicine group：Using Da Kening, the entitled miconazole nitrate cream of drug, specification：20 grams/, the term of validity：5 years,
Xi'an Yang Sen pharmaceutical Co. Ltds produce；Affected part is respectively smeared daily morning and evening 1 time, treatment cycle is 1 week.
Pure moxa stick control group：Using Moxibustion strip made of pure folium artemisiae argyi, the specification of Moxibustion strip is：Diameter 18mm, length
200mm, weight 20g；Each moxibustion 1 time daily morning and evening, treatment cycle are 1 week.
Medicinal moxa roll control group：The control group medicinal moxa roll ingredient of use is same《Chinese acupuncture and moxibustion》The 7th phase of volume 29 in July, 2009
Medicinal moxa roll described in " medicinal moxa roll moxibustion treatment treats tinea pedis observation of curative effect " text, specially：50% moxa, 30% tobacco leaf silk, 10%
Cortex Phellodendri, 10% kuh-seng, control group medicinal moxa roll specification are diameter 14mm, length 200mm.Application method is the same as 1-3 of the embodiment of the present invention
The application method of the treatment tinea pedis moxibustion item of offer.
2, diagnostic criteria
2.1 Western medicine diagnostic criteria
With reference to the 6th edition《Skin cypridology》The diagnostic criteria of middle macerative erosive and vesicle tinea pedis.
1. macerative erosive：Skin is macerated bleach through moisture at skin lesion, exposes red rotten to the corn face after wiping epidermis；Good hair
Between the 4th, 5 toes or between the 3rd, 4 toes, it is often accompanied by violent itch；Often secondary bacterial infection, normal foul smelling due to scratching.Blister
Type：Be frequently located in vola, blister wall thickness and be not easy brokenly, content is transparent, in groups or is dispersed in distribution, and blister surrounding skin is normal, number
Blister absorbs and dries furfur in the future, constantly falls off in small eckband shape or sleeve-like；At warts if secondary bacterial infection；This
Type often has itch.
2. winter of falling ill light summer weight.
3. the direct microscopy of fungi and culture are positive.
2.2 tcm diagnosis standard
It is promulgated with reference to State Administration of Traditional Chinese Medicine in 1994《TCM Dermatology disease Standardization of diagnosis and curative effect》In it is damp and hot under
The syndrome differential diagnosis standard of note type tinea pedis：Intensive blister, rotten to the corn flowing water, contamination is in blocks, itch pain or has fever；Thin lingual fur
Huang, slippery and rapid pulse；Fungal culture and microscopy are the positive.
3, the standard of curative effect evaluation
It is promulgated within 1993 according to the Ministry of Public Health《Antibacterials guideline of clinical investigations》Carry out efficacy evaluation.With skin lesion,
The degree of resolution of symptoms, the direct microscopy of fungi and culture negative conversion rate are foundation.
Depletion exponential=[total mark before (total mark after total mark-treatment before treatment) ÷ treatments] × 100%.
By recovery from illness, it is effective, progressive, it is invalid 4 grades evaluation.
Recovery from illness：Skin lesion, symptom completely disappear, depletion exponential 100%, and the direct microscopy of fungi and/or culture are negative；
It is effective：Skin lesion, resolution of symptoms index 60%-99% after treatment, itch degree is substantially reduced, and the direct microscopy of fungi is cloudy
Property or visible a small amount of broken, deformation mycelia, spore, culture it is negative；
Progress：In 20%-59%, the direct microscopy of fungi can positive and culture feminine gender for skin lesion, resolution of symptoms index after treatment；
In vain：Skin lesion, resolution of symptoms index ＜ 20% after treatment, Mycology examination are positive.
Recovery from illness and effective merging are calculated as total effective.
4, therapeutic effect counts
Each group curative effect is relatively shown in Table 1.
1 each group curative effect of table compares tables of data
As shown in Table 1, tinea pedis moxibustion item group total effective rate is 88.33%, is better than western medicine group, and P ＜ 0.05 have notable
Statistical significance；Tinea pedis moxibustion item group is better than pure moxa stick control group, and P ＜ 0.05 have significant statistical significance；Tinea pedis moxibustion item
Group is better than medicinal moxa roll control group, and P ＜ 0.05 have significant statistical significance.It is indicated above, what the embodiment of the present invention 1 provided
The effect for the treatment of tinea pedis moxibustion is significantly better than Da Kening, pure moxa stick and medicinal moxa roll control group.
Test example 2
Treatment tinea pedis 350 cases of moxibustion clinical treatment provided using the embodiment of the present invention 3, wherein man 190, female
160, the oldest 71 years old, age reckling 19 years old.The course of disease is most 1 month short, longest 40 years.It was treated through 1 week, recovery from illness 210,
Effective 130, it is progress 10,0 invalid, total effective rate is up to 100%.The result shows that the treatment foot that the embodiment of the present invention 3 provides
For tinea with moxibustion item to various tinea pedis, especially damp heat downward flowing type tinea pedis has the effect of highly significant.
Model case
1, Sun, man, 28 years old, bilateral interdigit had intensive phlysis, local skin acute pruritus then to be flowed after galling
Water.After the tinea pedis moxibustion moxibustion 2 weeks of the embodiment of the present invention 2, blister is without itch is without the direct microscopy of fungi is negative, clinical
Recovery from illness.
2, Song, female, 46 years old, moist skin soaking bleached at skin lesion between the 4th, 5 toes between bilateral toes the 3rd, 4 toes,
Expose red rotten to the corn face after wiping epidermis, with violent itch, foul smelling.With the tinea pedis moxibustion moxibustion 1 of the embodiment of the present invention 3
Zhou Hou, skin color is normal at skin lesion between the 4th, 5 toes between bilateral toes the 3rd, 4 toes, and itch is without stench is without fungi is straight
Connect microscopy feminine gender, clinical recovery.
3, bend certain, man, 57 years old, bilateral interdigit and foot bottom had in groups or are dispersed in a blister of distribution, itch unbearably, blister wall
Thick and be not easy brokenly, content is transparent, and blister surrounding skin is normal.After the tinea pedis moxibustion moxibustion 1 week of the embodiment of the present invention 1,
Bilateral interdigit and foot bottom blister are without itch is without the direct microscopy of fungi is negative, clinical recovery.
4, Mr. Li, male, left side interdigit, vola and dorsal portion have the dry white scales of skin that peel off, in small eckband shape or
Sleeve-like constantly falls off, the partially visible red phlysis of skin lesion, local skin acute pruritus after falling off.With the embodiment of the present invention 2
Tinea pedis moxibustion moxibustion 1 week after, the white scales of skin that peel off is without itch is without the direct microscopy of fungi is negative, clinical recovery.
5, hole, female, 35 years old, bilateral interdigit and right side foot bottom itch unbearably, there is phlysis, secondary thin after galling
There is warts in bacterium infection, with stench.After the tinea pedis moxibustion moxibustion 1 week of the embodiment of the present invention 3, itch without, warts disappears,
Stench is without Bacteria Culture is negative, and the direct microscopy of fungi is negative, clinical recovery.
Claims (4)
1. a kind for the treatment of tinea pedis moxibustion item, which is characterized in that be prepared from the following raw materials in parts by weight：
2. a kind of preparation method for treating tinea pedis moxibustion item, which is characterized in that include the following steps：
(1) each raw material is weighed by following parts by weight composition：40-50 parts of folium artemisiae argyi, 20-30 parts of tobacco leaf, 5-10 parts of corter pseudolaricis, tinea alba
5-10 parts of skin, 5-10 parts of the fruit of summer cypress, 5-10 parts of kuh-seng, 5-10 parts of Cortex Phellodendri, 5-10 parts of borneol；
(2) it takes corter pseudolaricis, favus skin, the fruit of summer cypress, kuh-seng, Cortex Phellodendri, borneol to be ground into fine powder, sieves with 100 mesh sieve, it will be thin after sieving
Powder is mixed with folium artemisiae argyi, tobacco leaf, and treatment tinea pedis moxibustion item is made.
3. the preparation method for the treatment of tinea pedis moxibustion item according to claim 2, which is characterized in that the Chinese medicine in the fine powder
Particle diameter is no more than 0.15mm.
4. the preparation method for the treatment of tinea pedis moxibustion item according to claim 2, which is characterized in that the treatment tinea pedis moxibustion
The specification of item is：Diameter 18mm, length 200mm, weight 20g.
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| CN105030888A (en) * | 2015-07-14 | 2015-11-11 | 华北理工大学 | Traditional Chinese medicine ointment for treating scale keratotic tinea manuum and tinea pedis |
| CN106236922A (en) * | 2016-08-30 | 2016-12-21 | 重庆主流生物工程有限公司 | A kind of Chinese medicine composition treating tinea pedis or tinea pedis and preparation method thereof |
| CN106344837A (en) * | 2016-11-14 | 2017-01-25 | 河南中医药大学 | Traditional Chinese medicine composition for treating dermatophytosis |
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| CN1323615A (en) * | 2001-06-01 | 2001-11-28 | 周志伦 | Bathing talcum powder |
| CN101797294A (en) * | 2010-01-20 | 2010-08-11 | 赵中央 | Chinese medicinal liquid for treating dermatophytosis |
| CN103751491A (en) * | 2011-10-13 | 2014-04-30 | 何克诚 | Medicament for treating dermatophytosis, psoriasis, dermatitis and flat wart, and treating method |
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|---|---|---|---|---|
| CN1323615A (en) * | 2001-06-01 | 2001-11-28 | 周志伦 | Bathing talcum powder |
| CN101797294A (en) * | 2010-01-20 | 2010-08-11 | 赵中央 | Chinese medicinal liquid for treating dermatophytosis |
| CN103751491A (en) * | 2011-10-13 | 2014-04-30 | 何克诚 | Medicament for treating dermatophytosis, psoriasis, dermatitis and flat wart, and treating method |
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