CN107822991A - A kind of feminine care wet tissue of bacteriostatic and disease prevention - Google Patents

A kind of feminine care wet tissue of bacteriostatic and disease prevention Download PDF

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Publication number
CN107822991A
CN107822991A CN201711259806.2A CN201711259806A CN107822991A CN 107822991 A CN107822991 A CN 107822991A CN 201711259806 A CN201711259806 A CN 201711259806A CN 107822991 A CN107822991 A CN 107822991A
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China
Prior art keywords
wet tissue
feminine care
care wet
bacteriostatic
decoction
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CN201711259806.2A
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Inventor
孟君
李伏君
滕晖
蒋加拉
伍实花
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Zhuzhou Qianjin Pharmaceutical Co Ltd
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Zhuzhou Qianjin Pharmaceutical Co Ltd
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Priority to CN201711259806.2A priority Critical patent/CN107822991A/en
Publication of CN107822991A publication Critical patent/CN107822991A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208Tissues; Wipes; Patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/37Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
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Abstract

The present invention relates to a kind of feminine care wet tissue of bacteriostatic and disease prevention, it is prepared by the method comprised the following steps:(1) rhizoma atractylodis, the coptis, folium eucalypti and peppermint are taken respectively, are dried, are mixed after crushing, obtain mixed material;(2) CO 2 fluid of the mixed material by the use of ethanol water as entrainer is subjected to supercritical extract, obtains extract;(3) extract is diluted with the solvent being made up of ethanol and propane diols, takes filtrate after filtering, obtain bacteriostatic and disease prevention decoction;(4) decoction is attached in base fabric, produced.The feminine care wet tissue of bacteriostatic and disease prevention provided by the invention can prevent bacterium infection of the women caused by private parts is unclean, so as to prevent the diseases such as urethral system infection, bacillary, mycotic, trichomonas vaginitis and nonspecific vaginitis;And stability is good, still there is good fungistatic effect after long-term placement, there is extensive market application value.

Description

A kind of feminine care wet tissue of bacteriostatic and disease prevention
Technical field
The present invention relates to female article field, and in particular to a kind of feminine care wet tissue its preparation method of bacteriostatic and disease prevention.
Background technology
Women goes to toilet, and substitutes toilet paper with napkin, is easy to cause infection, is allowed to suffer from urethral system infection, bacillary, mould The diseases such as property, trichomonas vaginitis and nonspecific vaginitis.These diseases are that the common disease of women, frequently-occurring disease are because of private parts Caused by unclean, so, pudendum cleaning is kept to ensureing that body of women health is very critically important, especially before menstrual period or sexual intercourse Afterwards, it is even more important.
Patent document CN102697671A discloses a kind of liquid medicine for wet tissue of bacteriostatic and disease prevention and preparation method thereof, the wet tissue medicine The active component of water contains the composition of following parts by weight:Atractylis oil 0.1-5 parts, jamaicin 0.01-0.5 parts, eucalyptus oil 0.01- 0.5 part, borneol 0.01-0.05 parts, menthol 0.01-0.5 parts.Although the wet tissue that the patent provides has bacteriostatic and disease prevention effect, To skin and vaginal mucosa without any excitant and side effect.With the patent similarly, most of existing feminine hygiene articles It is concerned only with prevention or therapeutic effect in itself, and the stability of product is closed when in use, in the case of especially long-term placement to product Note less, cause have certain difficulty in actual market popularization practical.
The content of the invention
A kind of it is an object of the present invention to the defects of overcoming prior art, there is provided the feminine care wet tissue of bacteriostatic and disease prevention.By Contain liquid component in wet tissue, place easily and occur going bad so as to influence the antibacterial of wet tissue in the case where being added without preservative Effect, wet tissue provided by the invention to raw material extracting method by optimizing, so as to true in the case where being not added with preservative Protecting products obtained therefrom has good stability.
Specifically, the invention provides a kind of feminine care wet tissue of bacteriostatic and disease prevention, the method by comprising the following steps It is prepared:
(1) rhizoma atractylodis, the coptis, folium eucalypti and peppermint are taken respectively, are dried, are mixed after crushing, obtain mixed material;
(2) CO 2 fluid of the mixed material by the use of ethanol water as entrainer is subjected to supercritical extract, Obtain extract;
(3) extract is diluted with the solvent being made up of ethanol and propane diols, takes filtrate after filtering, obtain bacteriostatic and disease prevention medicine Liquid;
(4) decoction is attached in base fabric, produced.
The present invention obtains extract using carbon dioxide supercritical extraction.By supercritical carbon dioxide and material to be separated Contact, make it that selectively polarity size, boiling point the height composition different with molecular size range be extracted successively.Due to The extracting object of the present invention is compound, therefore in extraction, the extraction of traditional Chinese medicine ingredients promotes other Chinese medicines due to the effect of dissolving each other The extraction of composition, and active ingredient is highly concentrated, impurity is few, and appearance color is preferable, has collaboration supplementary result.It is of the invention abundant The characteristic of each component in compound is considered, selects entrainer to carry out assisted extraction, so as to improve the selectivity of supercritical fluid, with Ensure that the target product of the present invention can be proposed farthest, while prevention effect is improved, the hair beyond the present invention Existing, the extract obtained by said extracted method has good stability after being prepared into wet tissue, has extremely strong market should With value.
The present invention is by largely putting into practice discovery, when the entrainer is the ethanol water of volumetric concentration 70~90%, Optimal extraction effect can be obtained, and gained wet tissue product has optimal stability.The preferably entrainer of the invention Dosage is the 1~10% of the mixed material quality.As the present invention preferred scheme, the carbon dioxide supercritical extraction Pressure is 20~40Mpa, and temperature is 30~50 DEG C.
The solvent that the present invention uses is formed by ethanol and mixed with propylene glycol.The present invention by largely putting into practice discovery, using by Both solvent mixed is diluted to the extract, can make the excitant in extraction process while being extracted Impurity sedimentation that is strong and influenceing stable effective ingredients, is then removed by follow-up settling step, so as to further improve The stability of wet tissue product.As the preferred scheme of the present invention, the solvent is by ethanol and propane diols with volume ratio 1~2:5~7 Mix.
The degree of step (3) described dilution can realize that preventing and treating and avoids menstruation infection effect with what this area was appreciated that Overstimulation is advisable, and in order to balance using effect and skin irritation, the extract is preferably diluted to former extraction by the present invention Take 70~90 times that liquid accumulates.
In order to improve market acceptance, the present invention adds natural perfume material or artificial flavors before filtration;Preferably, the day Right one or more of the spices in elscholtiza, borneol, oriental wormwood, peppermint, yellow wormwood artemisia;The artificial flavors be selected from plants essential oil and/ Or chemical synthesis essence, the plants essential oil are selected from Chinese torreya essential oil, mother chrysanthemum flower essential oil, daphne odera essential oil, pinecone essential oil, argy wormwood One or more in oil, thyme essential oil, eucalyptus quintessence oil, tea tree ethereal oil and camphor tree essential oil.
The base fabric is selected from non-woven fabrics or wet-strength paper.Before adhering liquid medicine, the base fabric first carry out it is suitably sized, so After carry out sterilization treatment.
Attachment of the present invention refers to soak base fabric with the decoction or the decoction is sprayed in base fabric.The spraying Specially:After carrying out atomization process to the decoction, high-pressure injection is in base fabric.
As a preferred embodiment of the present invention, the raw material is preferably the combination of following parts by weight:Rhizoma atractylodis 20~30 1~5 part of part, 10~30 parts of the coptis, 5~15 parts of folium eucalypti and peppermint.
In actual applications, the wet tissue should be independent packaging, to ensure using health.
The feminine care wet tissue of bacteriostatic and disease prevention provided by the invention can prevent bacterium sense of the women caused by private parts is unclean Dye, so as to prevent the diseases such as urethral system infection, bacillary, mycotic, trichomonas vaginitis and nonspecific vaginitis;It is and steady It is qualitative good, still there is good fungistatic effect after long-term placement, there is extensive market application value.
Embodiment
Following examples are used to illustrate the present invention, but are not limited to the scope of the present invention.
Embodiment 1
A kind of feminine care wet tissue of bacteriostatic and disease prevention is present embodiments provided, is prepared by the following method:
(1) difference rhizoma atractylodis 25kg, coptis 20kg, folium eucalypti 10kg, peppermint 3kg, dry, mixed after crushing, obtain mixed material;
(2) using the mixed material, by the use of the ethanol water of concentration 70% as entrainer, (dosage of entrainer is described The CO 2 fluid 10%) of mixed material quality, supercritical extract is carried out at being 40 DEG C in 30Mpa, temperature, must be extracted Liquid;
(3) with ethanol and propane diols with volume ratio 1.5:The extract is diluted to former extraction by 6 solvents mixed 80 times of liquid product, take filtrate, produce bacteriostatic and disease prevention decoction after filtering;
(4) high-pressure injection produces wet tissue by cutting, in the base fabric of sterilizing after the decoction being carried out into atomization process, Every wet tissue carries out independent packaging.
Embodiment 2
Compared with Example 1, differ only in, the step (1), (2) are specially:
(1) difference rhizoma atractylodis 20kg, coptis 10kg, folium eucalypti 5kg, peppermint 1kg, dry, mixed after crushing, obtain mixed material;
(2) using the mixed material, by the use of the ethanol water of concentration 70% as entrainer, (dosage of entrainer is described The CO 2 fluid 1%) of mixed material quality, supercritical extract is carried out at being 30 DEG C in 20Mpa, temperature, obtains extract.
Embodiment 3
Compared with Example 1, differ only in, the step (1), (2) are specially:
(1) difference rhizoma atractylodis 30kg, coptis 30kg, folium eucalypti 15kg, peppermint 5kg, dry, mixed after crushing, obtain mixed material;
Using the mixed material, by the use of the ethanol water of concentration 90% as entrainer, (dosage of entrainer is the mixing The CO 2 fluid 10%) of material quality, supercritical extract is carried out at being 50 DEG C in 40Mpa, temperature, obtains extract.
Embodiment 4
Compared with Example 1, differ only in, the solvent that the step (3) uses is by ethanol and propane diols with volume ratio For 1:10 mix.
Embodiment 5
Compared with Example 1, differ only in, the solvent that the step (3) uses is by ethanol and propane diols with volume ratio For 1:2 mix.
Comparative example 1
Compared with Example 1, differ only in, the solvent of step (3) described dilution is 70% ethanol water.
Comparative example 2
Compared with Example 1, differ only in, the formula referenced patent document CN102697671A embodiments 2 of liquid medicine are public The formula opened, is specifically comprised:Atractylis oil 19g, jamaicin 0.5g, eucalyptus oil 0.8g, borneol 0.13g, peppermint oil 1.5g.(close Count 21.93g)
Preparation method:
1) each composition is weighed according to proportioning, it is standby;
2) Atractylis oil for weighing formula ratio (prepares) 19g according to the method for embodiment 1, is dissolved in 500g 95% ethanol, Fully after dissolving, bottom white insoluble liq is removed with separatory funnel, the export of upper strata alcoholic solution, obtains rhizoma atractylodis oleyl alcohol, it is standby With;
3) peppermint, borneol are well mixed, are separately added into jamaicin, rhizoma atractylodis oleyl alcohol, eucalyptus oil and 2500g glycerine, Well mixed, the ethanol constant volume for adding 95% arrives 10kg, and ultrasonic wave dissolves, to pink colour clear solution, produced.
Passing through according to high-pressure injection after the decoction is carried out into atomization process with the step of embodiment 1 (4) identical mode Cut, in the base fabric of sterilizing, produce wet tissue, every wet tissue carries out independent packaging.
Experimental example:Long-term bacteriostatic experiment
After the wet tissue that each embodiment and comparative example are provided is placed 0,2,6 month at normal temperatures respectively, bacteriostasis rate is tested, it is empty White control is undressed blank sterilizing non-woven fabrics.Experimental strain:Staphylococcus aureus, Candida albicans, Escherichia coli, Pseudomonas aeruginosa, hemolytic streptococcus;Specific experiment step refers to《15979-2002 disposable sanitary articles sanitary standards》Rule It is fixed.As a result as shown in table 1~3.
Table 1:0 month bacteriostasis rate (%)
Staphylococcus aureus Candida albicans Escherichia coli Pseudomonas aeruginosa Hemolytic streptococcus
Blank control 0 0 0 0 0
Embodiment 1 99.7 99.6 99.1 99.5 99.3
Embodiment 2 99.0 99.1 99.6 99.5 99.4
Embodiment 3 99.4 99.8 99.6 99.4 99.0
Embodiment 4 98.0 98.2 98.4 98.9 98.2
Embodiment 5 98.9 99.2 99.0 98.5 99.0
Comparative example 1 96.5 97.9 96.2 97.2 98.1
Comparative example 2 98.0 98.2 97.9 98.9 99.0
Table 2:2 months bacteriostasis rates (%)
Staphylococcus aureus Candida albicans Escherichia coli Pseudomonas aeruginosa Hemolytic streptococcus
Blank control 0 0 0 0 0
Embodiment 1 99.1 99.1 98.5 99.0 98.9
Embodiment 2 98.5 98.8 99.0 99.2 99.0
Embodiment 3 99.2 99.1 99.0 99.0 98.9
Embodiment 4 97.5 97.6 98.0 98.2 97.5
Embodiment 5 97.9 98.8 98.5 97.5 98.0
Comparative example 1 95.9 96.4 95.5 96.1 96.8
Comparative example 2 95.3 97.6 95.8 97.6 95.8
Table 3:6 months bacteriostasis rates (%)
From result above, wet tissue provided by the invention has good fungistatic effect, and is being not added with preservative In the case of through long-term biocidal property of placing keep stable.
Although above the present invention is made to retouch in detail with general explanation, embodiment and experiment State, but on the basis of the present invention, it can be made some modifications or improvements, this is apparent to those skilled in the art 's.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, are belonged to claimed Scope.

Claims (10)

1. the feminine care wet tissue of a kind of bacteriostatic and disease prevention, it is characterised in that be prepared by the method comprised the following steps:
(1) rhizoma atractylodis, the coptis, folium eucalypti and peppermint are taken respectively, are dried, are mixed after crushing, obtain mixed material;
(2) CO 2 fluid of the mixed material by the use of ethanol water as entrainer is subjected to supercritical extract, must extracted Take liquid;
(3) extract is diluted with the solvent being made up of ethanol and propane diols, takes filtrate after filtering, obtain bacteriostatic and disease prevention decoction;
(4) decoction is attached in base fabric, produced.
2. feminine care wet tissue according to claim 1, it is characterised in that the entrainer is volumetric concentration 70~90% Ethanol water.
3. feminine care wet tissue according to claim 1 or 2, it is characterised in that the dosage of the entrainer is described mixed Close the 1~10% of material quality.
4. the feminine care wet tissue according to claims 1 to 3 any one, it is characterised in that the carbon dioxide is super to be faced The pressure of boundary's extraction is 20~40Mpa, and temperature is 30~50 DEG C.
5. feminine care wet tissue according to claim 1, it is characterised in that step (3) solvent is by ethanol and the third two Alcohol is with volume ratio 1~2:5~7 mix.
6. feminine care wet tissue according to claim 1, it is characterised in that add natural perfume before step (3) described filtering Material or artificial flavors;
Preferably, one or more of the natural perfume material in elscholtiza, borneol, oriental wormwood, peppermint, yellow wormwood artemisia;The artificial fragrant Material is selected from plants essential oil and/or chemical synthesis essence, and the plants essential oil is selected from Chinese torreya essential oil, mother chrysanthemum flower essential oil, daphne odera essence One or more in oil, pinecone essential oil, mugwort oil, thyme essential oil, eucalyptus quintessence oil, tea tree ethereal oil and camphor tree essential oil.
7. feminine care wet tissue according to claim 1, it is characterised in that the base fabric is selected from non-woven fabrics or wet-strength paper.
8. feminine care wet tissue according to claim 7, it is characterised in that the attachment refers to soak base with the decoction The decoction is sprayed in base fabric by cloth.
9. feminine care wet tissue according to claim 8, it is characterised in that the spraying is specially:The decoction is carried out After atomization process, high-pressure injection is in base fabric.
10. the feminine care wet tissue according to claim 1~9 any one, it is characterised in that in step (1), take rhizoma atractylodis 20~30 parts, 10~30 parts of the coptis, 5~15 parts of folium eucalypti, 1~5 part of peppermint.
CN201711259806.2A 2017-12-04 2017-12-04 A kind of feminine care wet tissue of bacteriostatic and disease prevention Pending CN107822991A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107753349A (en) * 2017-12-04 2018-03-06 株洲千金药业股份有限公司 A kind of feminine care wet tissue for preventing and treating menstruation infection

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106727094A (en) * 2015-11-20 2017-05-31 青岛华南盛源果业有限公司 A kind of wet tissue for ladies only

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106727094A (en) * 2015-11-20 2017-05-31 青岛华南盛源果业有限公司 A kind of wet tissue for ladies only

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107753349A (en) * 2017-12-04 2018-03-06 株洲千金药业股份有限公司 A kind of feminine care wet tissue for preventing and treating menstruation infection
CN107753349B (en) * 2017-12-04 2021-01-26 株洲千金药业股份有限公司 Female nursing wet tissue for preventing and treating menstrual infection

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Application publication date: 20180323