CN102846870B - External anti-inflammatory drug from the Miao nationality and production process thereof - Google Patents

External anti-inflammatory drug from the Miao nationality and production process thereof Download PDF

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CN102846870B
CN102846870B CN201210304080.0A CN201210304080A CN102846870B CN 102846870 B CN102846870 B CN 102846870B CN 201210304080 A CN201210304080 A CN 201210304080A CN 102846870 B CN102846870 B CN 102846870B
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herba
externally applied
medical material
applied anti
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CN102846870A (en
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袁涛忠
何兆辉
黄玉珍
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Abstract

The invention relates to an external anti-inflammatory drug prepared from the raw materials of medicinal plants used by the Miao nationality. The external anti-inflammatory drug comprises the following components: 2-4 parts of honeysuckle, 1-3 parts of rhizoma cibotii, 1-3 parts of solidago decurrens, 1-2 parts of woad, 2-4 parts of fringed iris, 1-3 parts of dandelion and 2-3 parts of chrysanthemum. The external anti-inflammatory drug is an integrity of anti-inflammatory agent, cleaning agent, bath agent and antipruritic agent. The indications and usages of the external anti-inflammatory drug are more than those of the currently widely used drugs and preparations, such as Daktarin cream, calamine and menthol lotion, Jieeryin, Fu Yanjie, external zijin troches, Chuanbai anti-itching lotion, Shibiling anti-itching anti-inflammatory lotion and Sanwei heat-clearing anti-itching lotion. The preparation prepared from the formula contains no chemicals, and is a pure natural medicinal plant preparation; besides, the external anti-inflammatory drug has no toxic or side effect, or irritation on skin and mucosa of adult and infant, and is an essential household medicine.

Description

Miao ethnic group's externally applied anti-inflammation medicine and preparation technology
Technical field
The present invention relates to Miao ethnic group's medicinal plants is the externally applied anti-inflammation medicine that raw material is made.
Background technology
Women's gynecological inflammation, infantile eczema, baby's diaper dermatitis, child because of mosquito bite the scytitis that causes etc. be clinical common inflammation, be also the commonly encountered diseases in family health care.A lot of doctors, medicine enterprise are making great efforts safe, the evident in efficacy remedy,topical of innovation for these inflammation treatments.
At present, though have these medicines, the preparation of a multitude of names, all exist the not ideal enough or function singleness of curative effect limitation.So clinical, urgently develop a kind of nontoxic, non-stimulated to human body apparatus urogenitalis skin, mucosa, infant skin, mucosa, not strong containing broad-spectrum disease resistance pathogenic microorganism, the antiinflammation of chemical addition agent, applied range, externally applied anti-inflammation medicine evident in efficacy.
Antibiotic medicine of the present invention, that inventor is adhering under the prerequisite of Seedling medicine reality principle, according to spontaneous medical experience, application Seedling medicinal knowledge and modern medicine are gained knowledge Miao ethnic group's Category of the diseases such as the numerous different topical therapeutic of Miao ethnic group's prolonged application among the people " vulvitis; vaginitis; urethritis; infant eczema, diaper rash (baby's diaper dermatitis); miliaria alba; insect dermatitis " are analysed in depth after research to prescription again, the breen made from modern medicines preparation technique, clear and bright, the external preparation that has special aroma, stable in properties.
Summary of the invention
Main purpose of the present invention is to provide a kind of pure natural, to human body apparatus urogenitalis skin, mucosa, infant skin, mucosa are nontoxic, non-stimulated, not containing strong externally applied anti-inflammation medicine and the preparation technology of broad-spectrum disease resistance pathogenic microorganism, antiinflammation of chemical addition agent.
For achieving the above object, the technical solution adopted in the present invention is: a kind of externally applied anti-inflammation medicine, is comprised of the component of following weight ratio:
Radix Ophiopogonis (Latin name: Lonicera japonica Thunb; Miao: the nearly sound word of Bangx ghab dlad(Chinese: Bang Ga society)) 2~4 parts;
Rhizoma Cibotii (Latin name: Woodwardia japonica(L.F.) Smith; Miao: Ghaib xad jad(lid is lower good)) 1~3 part;
Herba Solidaginis (Latin name: Solidago decurrens Lour.; Miao: the good flat powder of Jab biex fiex()) 1~3 part;
Isatis indigotica Fort. (Latin name: Isatis indigotica Fort.; Miao: your nest of Nix vob()) 1~2 part;
Herba Iridis japonicae (Latin name: Iris japonica Thunb; Miao: Vob dak dlangd(nest reaches still)) 2~4 parts;
Herba Taraxaci (Latin name: Taraxacum mongolicum Hand.-Mazz.; Miao: Vob eb wel(nest is oh recessed)) 1~3 part;
Herba Dendranthematis indici (Latin name: Chrysanthemum indicum L.; Miao: Vob senb lot(nest item is glutinous)) 2~3 parts.
Medicine of the present invention is made as spray or washing liquid conventionally, is convenient to hydro-peening or is watered take a shower or clean.Medicine of the present invention will be realized goal of the invention only needs component as above, but also can add other fragrant extract etc. in component of the present invention, additional other function or with the composite use of other preparation.
Further preferred: 2 parts described of 3 parts of 1 part of 2 parts of 2 parts of 3 parts of Radix Ophiopogoniss, Rhizoma Cibotii, Herba Solidaginiss, Isatis indigotica Fort., Herba Iridis japonicae, Herba Taraxacis, 3 parts, Herba Dendranthematis indici.
Further preferred: 2 parts described of 4 parts of 1 part of 3 parts of 3 parts of 3 parts of Radix Ophiopogoniss, Rhizoma Cibotii, Herba Solidaginiss, Isatis indigotica Fort., Herba Iridis japonicae, Herba Taraxacis, 2 parts, Herba Dendranthematis indici.
Further preferred: 3 parts described of 4 parts of 2 parts of 3 parts of 3 parts of 4 parts of Radix Ophiopogoniss, Rhizoma Cibotii, Herba Solidaginiss, Isatis indigotica Fort., Herba Iridis japonicae, Herba Taraxacis, 3 parts, Herba Dendranthematis indici.
Accordingly, the preparation technology of externally applied anti-inflammation medicine of the present invention, step comprises:
After this prescription pulverizing medicinal materials with the airtight dipping of 95% ethanol, with medicated powder even moistening degree of being expanded to fully;
Medicated powder after dipping evenly, degree of tightness as one man packs percolator into, adds 95% ethanol, and addition is 2 times of this prescription medical material weight, airtight dipping 48h; Described degree of tightness is exactly unanimously to make medicated powder degree of tightness consistent as far as possible, and for example evenly loose packing into, without compression.
With medical material 1000g outflow per minute 2mL speed percolation, synchronized 60% ethanol that adds, addition is 2 times of this prescription medical material weight; Collection is filtered and when liquid measure reaches 3.5 times of this prescription medical material weight, is obtained percolate (1);
Continuous percolation, the synchronized purified water that adds, addition is 2 times of this prescription medical material weight; Collection is filtered and when liquid measure reaches 2 times of this prescription medical material weight, is obtained percolate (2);
Continuous percolation is colourless only to the liquid of filtering, and obtains the continuous liquid of filtering;
Percolate (1), (2) obtain concentrated solution after reclaiming ethanol; The continuous liquid of filtering to adding this prescription medical material weight 1/2nd weight in concentrated solution, mix, standing, considered, then add the continuous liquid of filtering quantitative finished product.
Further, described recovery ethanol adopts reduced pressure distillation process to carry out.
Further, pulverizing medicinal materials is to medium powder fineness.The medium powder fineness that namely " Chinese Pharmacopoeia " stipulated.
Further, during the described airtight dipping medical material of 95% ethanol, the liquid-solid mass ratio of 95% ethanol and medical material powder is 2:1, airtight placement 2h.
Further, described purified product 1ml is equivalent to crude drug 1g.
After the product application of making by this technique, show this extraction scheme craft science, reasonable, novel, the quality of the pharmaceutical preparations meets every regulation requirement, remarkably productive, without toxicity, is convenient to produce and application.
In view of the chemical composition of Miao Ethnomedicine compound recipe very complicated, and the physical and chemical reaction occurring in processing and making process likely causes the chemical composition having disappear or produce new compound, therefore, finding the extraction of this Miao Ethnomedicine compound recipe is made its elaboration products (compound recipe) become " natural combination chemical combination storehouse " and produces the effect of " multiple target effect ", is the basic ideas of this prescription Miao Ethnomedicine separation and Extraction.From these basic ideas, inventor carries out preparation process design according to the character of this prescription Miao ethnic group medicinal plants and this composing prescription preparation application target, application approach.Object Shi Jiangben prescription Miao ethnic group medicinal plants processing of crude drugs is made application safety, definite effect, the stable in properties, controlled of the certain specification that is suitable for application form, and economic goods.
This preparation process is deferred to the separating technology design principle of " safety, effectively, stable, homogeneous, economy ", according to the dissolution properties of various compositions in solvent in each medical material in this Miao Ethnomedicine prescription, select ethanol to make solvent, according to " percolation " (Chinese name republic pharmacopeia 2010 editions one), adopt accurate, easy, representative, quantifiable comprehensive evaluation index, this Miao Ethnomedicine prescription is carried out to compound recipe extraction.In extraction process, pay attention to solvent, the conditions such as the concentration of solvent, time are on extracting separated impact, have designed with opposed polarity solvent, variable concentrations solvent, at normal temperatures in same container, extract the extraction scheme of this prescription medicinal plants composition.
Miao ethnic group's medicinal plants that forms this prescription is loaded " Chinese Plants will " or as document such as " Plants From Guizhou will " all.What be wherein written into the Pharmacopoeia of the People's Republic of China has Radix Ophiopogonis, Herba Dendranthematis indici, Herba Solidaginis, Isatis indigotica Fort., a Herba Taraxaci; Rhizoma Cibotii is written into the 93rd page of " Guizhou Province's Chinese crude drug quality standard " version in 1988; Herba Iridis japonicae is written into the 495th page of " Plants From Guizhou will " the 6th volume.
Useful technique effect of the present invention:
This prescription is completely different with the prescription of the preparation of existing treatment " vaginitis, urethritis, infant eczema, diaper disease, erythema (red hip), miliaria alba, insect dermatitis ".With regard to application site, function and the usage of the single medicinal plants of this prescription, be all very different with the application of state-promulgated pharmacopoeia and contained these medicinal plants of medicine monograph.
The bioactive substance of the contained flavonoid of this composing prescription preparation, terpenoid, alkaloids, sterols, volatile oil, glucide class, organic acid etc. all comes from natural plants, they or directly act on body surface, mucosa, or absorb through skin, mucosa, given play to biological effect.The indigo alkaloid such as indirubin in preparation, Rhizoma Iridis Tectori isoflavone, phenolic acids, glycoside, volatile oil, sterols, Kaempferol-rutinoside, chlorogenic acid, isochlorogenic acid, taraxasterol, choline etc. has resisting pathogenic microbes, infection, antiinflammatory, suppress increasing of capillary of skin permeability, suppress the generation of prostaglandin E, analgesia, rheumatism, anastalsis, there is inhibition connective tissue proliferation, suppress glue unit synthetic, anti peroxidation of lipid, remove free radical, promote cardiovascular system blood flow, antiplatelet aggregation, improve immunity of organisms, the effect of selective control estrogen receptor.
This composing prescription preparation has more indication.In wide model application over more than 10 years, shown the antipathogen with wide spectrum, improved skin resistance, control inflammation rapidly, antipruritic, to promote damaged tissues regeneration and skin ulcer face healing, the effect of avoiding secondary infection.Be applied to topical therapeutic women's episioitis, vaginitis, can control inflammation rapidly, antipruritic, pain relieving, elimination swelling, rotten to the corn effect; Topical therapeutic women urethritis, has the effect of rapid alleviation frequent micturition, urgent micturition, dysurea; Topical therapeutic infant eczema, diaper rash have rapidly and control inflammation, and obviously shorten the course of disease, have pain relieving, eliminate erythema, pimple, herpes, antipruritic, promoting muscle growth functions; Topical therapeutic insect dermatitis, has antiallergic, disappear erythema, pimple, welt rapidly, the effect of control secondary infection; Topical therapeutic miliaria alba has the macule that disappears rapidly, pimple, antipruritic, to prevent secondary infection effect; Topical therapeutic condyloma acuminatum, genital herpes, shown have wide spectrum antipathogen, control inflammation rapidly, control and eliminate pimple, vesicle, erosion, ulcer sexually transmitted disease (STD) and become, control and have a joke, the vegetation that disappears, promote repair of damaged tissues, avoid the effect of secondary infection.Child takes a shower with this composing prescription preparation, can effectively prevent the skin infections such as infant eczema, diaper rash, miliaria alba, eliminates rapidly the effect that children's's skin is uncomfortable, protect the tender skin of children's; Women, with the demibain of this composing prescription preparation or flushing, can prevent vulvitis, vaginitis, the inflammation such as urethritis, prevention infection effectively.
And the externally applied anti-inflammation medicine of this prescription integrates antiinflammatory, irrigation, bath shampoo, pruritus etc., its indication and purposes more than so far still clean, external zijin troche, Chuanbaizhiyang Lotion of the miconazole of extensive use, calamine and menthol lotion, JIEERYIN, woman's inflammation, execute than the medicines such as Ling Zhiyangxiaoyanshui, San Wei Qing Re Zhi Yang Xiji, preparation.And this composing prescription preparation does not add chemical agent, it is pure natural medicinal plants preparation; To adult with infant skin, mucosa, there is no toxic and side effects, nonirritant.
The specific embodiment
Preferred prescription and the preparation technology embodiment of externally applied anti-inflammation medicine of the present invention are provided below.
Embodiment mono-
2 parts of Radix Ophiopogoniss, 1 part of Rhizoma Cibotii, 1 part of Herba Solidaginis, 1 part of Isatis indigotica Fort., 2 parts of Herba Iridis japonicae, 1 part of Herba Taraxaci, 2 parts, Herba Dendranthematis indici; Total amount 1000g.
Preparation process:
Medical material was all crushed to 50 mesh sieve fineness together, added 2kg95% ethanol, airtight dipping medical material 2h; Can obtain the medicated powder that moistening is sufficiently uniformly expanded;
Medicated powder after dipping evenly, degree of tightness as one man packs percolator into, and for guaranteeing that degree of tightness is consistent, spy arranges the dividing plate with holes of layering; Add 2kg 95% ethanol, airtight dipping 48h;
With medical material 1000g outflow per minute 2mL speed percolation, synchronized 60% ethanol that adds, addition is 2kg; Collection is filtered and when liquid measure reaches 3.5kg, is obtained percolate (1);
Continuous percolation, the synchronized purified water that adds, addition is 2kg; Collection is filtered and when liquid measure reaches 2kg, is obtained percolate (2);
Continuous percolation is colourless only to the liquid of filtering, and obtains the continuous liquid of filtering;
Percolate (1), (2) obtain concentrated solution after reclaiming ethanol; The continuous liquid of filtering to adding this prescription medical material weight 1/2nd weight in concentrated solution, mix, standing, considered, then add the continuous liquid of filtering quantitative that 1ml is equivalent to the finished product of crude drug 1g.
Embodiment bis-
3 parts of Radix Ophiopogoniss, 2 parts of Rhizoma Cibotii, 2 parts of Herba Solidaginiss, 1 part of Isatis indigotica Fort., 3 parts of Herba Iridis japonicae, 2 parts of Herba Taraxacis, 3 parts, Herba Dendranthematis indici; Total amount 1000g.
Preparation process:
Medical material was all crushed to 30 mesh sieve fineness together, added 2kg95% ethanol, airtight dipping medical material 2h; Obtain the medicated powder that moistening is sufficiently uniformly expanded;
Medicated powder after dipping evenly, loosely packs percolator into, adds 2kg 95% ethanol, airtight dipping 48h;
With medical material 1000g outflow per minute 2mL speed percolation, synchronized 60% ethanol that adds, addition is 2kg; Collection is filtered and when liquid measure reaches 3.5kg, is obtained percolate (1);
Continuous percolation, the synchronized purified water that adds, addition is 2kg; Collection is filtered and when liquid measure reaches 2kg, is obtained percolate (2);
Continuous percolation is colourless only to the liquid of filtering, and obtains the continuous liquid of filtering;
Percolate (1), (2) obtain concentrated solution after reclaiming ethanol; The continuous liquid of filtering to adding this prescription medical material weight 1/2nd weight in concentrated solution, mix, standing, considered, then add the continuous liquid of filtering quantitative that 1ml is equivalent to the finished product of crude drug 1g.
Embodiment tri-
3 parts of Radix Ophiopogoniss, 3 parts of Rhizoma Cibotii, 3 parts of Herba Solidaginiss, 1 part of Isatis indigotica Fort., 4 parts of Herba Iridis japonicae, 2 parts of Herba Taraxacis, 2 parts, Herba Dendranthematis indici; Total amount 1000g.
Preparation method is with embodiment mono-.
Embodiment tetra-
4 parts of Radix Ophiopogoniss, 3 parts of Rhizoma Cibotii, 3 parts of Herba Solidaginiss, 2 parts of Isatis indigotica Fort., 4 parts of Herba Iridis japonicae, 3 parts of Herba Taraxacis, 3 parts, Herba Dendranthematis indici; Total amount 1000g.
Preparation method is with embodiment mono-.
This composing prescription preparation is applicable to women's episioitis, vaginitis, and urethritis, infant eczema, diaper rash, the topical therapeutic of the skin infection illness such as insect dermatitis, miliaria alba, is applicable to condyloma acuminatum, the topical therapeutic of genital herpes; Also be applicable to prevent the skin infections such as infant eczema, diaper rash, miliaria alba, be applicable to prevent women's episioitis, vaginitis, the inflammation such as urethritis.
Usage and dosage:
A. local wiping: get sterilized cotton swabs (gauze) and dip this preparation wiping affected part or dip this preparation with gauze and roll over to open and be applied to affected part.
B. the demibain of being grown up: by this preparation and clean warm water 1:19 or 1:49(V:V) after dilution, for demibain.Apply every day 1~2 time or for several times not etc., according to being used for the treatment of or determine for prevention, general prevention once a day, and employing 1:49(V:V) concentration.
C. child's shower: by this preparation and clean warm water 1:49 or 1:99(V:V), after dilution, for child, take a shower.Apply every day 1~2 time or for several times not etc., according to being used for the treatment of or determining for prevention.
D. gynaecologic processing: be applicable to the treatment of the clean vagina of the daily flushing of women and vagina.By this preparation and clean warm water 1:9 or 1:19(V:V) after dilution, pour into special flusher, for rinsing.Every day 1-2 time or for several times not etc., according to being used for the treatment of or determining for prevention.
E. soak: for male patients with condyloma acuminata, the topical therapeutic of skin lesion due to genital herpes.This preparation and clean warm water 1:9 or 1::19(V:V) after dilution, contain immersion with in container, soak skin lesion position, each 20~30 minutes, for several times, determined according to patient every day.
Points for attention:
A. this preparation is the external preparation of topical therapeutic (prevention) use, whether carries out associated treatment or systemic treatment simultaneously and should according to conditions of patients, be determined by doctor while using this preparation for treating.
B. demibain, flushing, immersion institute water must be clean warm water, and water temperature is between 37~40 ℃.
C. each demibain, soak and finish after, wipe away dryly, keep skin lesion local clean, dry.
D. menstrual period or colporrhagia phase are forbidden gynaecologic processing, and anemia of pregnant woman is cautious use of gynaecologic processing.
E. flusher must be used aseptic irrigator.
F. people's one use such as " bubble basin ", " immersion container ", " flusher ", " bath towel ", forbids cross-reference.
G. Zuo Yu Time has people to manage, as the dizzy Li evil of Halo occurred, emitting the Should such as cold sweat to stop immediately demibain.
The effect of this composing prescription preparation
This composing prescription preparation in the application over year, shows safety more than 10, effectively.Do not occur Mucocutaneous paying property of thorn, without sensitization, nontoxic, have no side effect.For topical therapeutic " vaginitis, vulvitis, pruritus vulvae; vulval ulcer, female urethra is scorching, bady's diaper disease, erythema, miliaria alba and mosquito bite ", there is uniqueness, significant effect, especially with " demibain " control female vagina, vulvitis, urethritis, " demibain " combination " flushing " control female vagina, " demibain " treatment vulvitis, pruritus vulvae and " children, children's take a shower " prevention bady's diaper disease, erythema, miliaria alba etc. can be received the therapeutic effect getting instant result.Therapeutic effect compared with the similar preparation of doctor trained in Western medicine, the traditional Chinese medical science has comparative advantages.Now the health-care good product of herbal.
1, observe for " children, children's take a shower " more than 30 examples, they,, in this preparation wiping control infant eczema, diaper rash for cradle, obtain remarkable result, after 3 months, use this preparation " shower " person, all do not suffer from eczema, diaper rash, erythema, preventive effect is remarkable.
2, more than 100 routine women use this preparation " demibain " and wiping treatment urethritis, vulvitis, pruritus vulvae, in treatment for the first time, frequent micturition, urgent micturition, dysurea symptom, pruritus vulvae causalgia symptoms etc. are alleviated at once, for the second time after treatment, above-mentioned symptom and leucorrhea abnormal lapse to gradually, light disease person clinical cure.Receive the therapeutic effect getting instant result.Daily for clean " privates ", effectively prevented urethritis, vaginitis, the generation of vulvitis.
3, with this preparation, in " children, children's take a shower ", prevent and treat miliaria alba, after once taking a shower, " miliaria " having occurred gradually row disappears, and secondary infection does not occur; Summer and autumn with this preparation in taking a shower ", effectively prevent and treat child, child's miliaria alba.
4, with this preparation for treating " insect dermatitis ", received at once antipruritic, ease the pain and swelling, prevention secondary infection positive effect.
5, by the cauliflower form vegetation of the wiping of this preparation, one week interior condyloma acuminatum of soaking therapy male patients with condyloma acuminata more than 10 example, be eliminated, secondary infection is controlled; By the wiping of this preparation, soaking therapy genital herpes more than 10 examples, red and swollen, pain disappears; The dry incrustation of rotten to the corn face after vesicle is broken, without secondary infection.

Claims (10)

1. an externally applied anti-inflammation medicine, the component that medicine material is following weight ratio:
2~4 parts of Radix Ophiopogoniss;
1~3 part of Rhizoma Cibotii;
1~3 part of Herba Solidaginis;
1~2 part of Isatis indigotica Fort.;
2~4 parts of Herba Iridis japonicae;
1~3 part of Herba Taraxaci;
2~3 parts, Herba Dendranthematis indici.
2. a kind of externally applied anti-inflammation medicine according to claim 1, is characterized in that: 2 parts described of 3 parts of 1 part of 2 parts of 2 parts of 3 parts of Radix Ophiopogoniss, Rhizoma Cibotii, Herba Solidaginiss, Isatis indigotica Fort., Herba Iridis japonicae, Herba Taraxacis, 3 parts, Herba Dendranthematis indici.
3. a kind of externally applied anti-inflammation medicine according to claim 1, is characterized in that: 2 parts described of 4 parts of 1 part of 3 parts of 3 parts of 3 parts of Radix Ophiopogoniss, Rhizoma Cibotii, Herba Solidaginiss, Isatis indigotica Fort., Herba Iridis japonicae, Herba Taraxacis, 2 parts, Herba Dendranthematis indici.
4. a kind of externally applied anti-inflammation medicine according to claim 1, is characterized in that: 3 parts described of 4 parts of 2 parts of 3 parts of 3 parts of 4 parts of Radix Ophiopogoniss, Rhizoma Cibotii, Herba Solidaginiss, Isatis indigotica Fort., Herba Iridis japonicae, Herba Taraxacis, 3 parts, Herba Dendranthematis indici.
5. according to a kind of externally applied anti-inflammation medicine described in claim 1 or 2 or 3 or 4, it is characterized in that: described externally applied anti-inflammation medicine is prepared as spray or washing liquid.
6. the preparation technology of externally applied anti-inflammation medicine according to claim 5, step comprises:
After this prescription pulverizing medicinal materials with the airtight dipping of 95% ethanol, with medicated powder even moistening degree of being expanded to fully;
Medicated powder after dipping evenly, degree of tightness as one man packs percolator into, adds 95% ethanol, and addition is 2 times of this prescription medical material weight, airtight dipping 48h;
With medical material 1000g outflow per minute 2mL speed percolation, synchronized 60% ethanol that adds, addition is 2 times of this prescription medical material weight; Collection is filtered and when liquid measure reaches 3.5 times of this prescription medical material weight, is obtained percolate (1);
Continuous percolation, the synchronized purified water that adds, addition is 2 times of this prescription medical material weight; Collection is filtered and when liquid measure reaches 2 times of this prescription medical material weight, is obtained percolate (2);
Continuous percolation is colourless only to the liquid of filtering, and obtains the continuous liquid of filtering;
Percolate (1), (2) obtain concentrated solution after reclaiming ethanol; The continuous liquid of filtering to adding this prescription medical material weight 1/2nd weight in concentrated solution, mix, standing, considered, then add the continuous liquid of filtering quantitative finished product.
7. the preparation technology of a kind of externally applied anti-inflammation medicine according to claim 6, is characterized in that: described recovery ethanol adopts reduced pressure distillation process to carry out.
8. the preparation technology of a kind of externally applied anti-inflammation medicine according to claim 6, is characterized in that: described pulverizing medicinal materials is to medium powder fineness.
9. the preparation technology of a kind of externally applied anti-inflammation medicine according to claim 6, is characterized in that: during the described airtight dipping medical material of 95% ethanol, the liquid-solid mass ratio of 95% ethanol and medical material powder is 2:1, airtight placement 2h.
10. the preparation technology of a kind of externally applied anti-inflammation medicine according to claim 6, is characterized in that: described purified product 1ml is equivalent to crude drug 1g.
CN201210304080.0A 2012-08-23 2012-08-23 External anti-inflammatory drug from the Miao nationality and production process thereof Expired - Fee Related CN102846870B (en)

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