CN102836306B - Traditional Chinese medicine combination for treating horse traumatic injuries and preparation method of same - Google Patents
Traditional Chinese medicine combination for treating horse traumatic injuries and preparation method of same Download PDFInfo
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Abstract
The invention provides a Chinese medicine combination for treating horse traumatic injuries and a preparation method of same. The Chinese medicine combination comprises the following medical raw materials of dragon blood, frankincense, myrrh, acacia catechu, keel, pyrite and musk and can further comprise peach kernel, safflower, corydalis tuber, resina liquidambaris, rhizoma drynariaes and sappan wood. The invention has the benefits that the Chinese medicine combination totally prepared from Chinese herbal medicines has a broad source of raw materials, is at a low cost and has a high therapeutic rate without medical residues or toxic side effect; the formula adopting medicines for activating blood, alleviating pain, removing stasis, stopping bleeding, dispersing swellings, relieving pus, reuniting bones and treating wounds is reasonable, and the purposes of promoting the healing of contusions, purulent wounds, fractures and other traumatic injuries, reuniting tendons and the bones, dispersing swellings, alleviating pain, relieving pus and regenerating tissue can be quickly achieved; the Chinese medicine combination can also be used for treating ruptured fistula, scrofula, breast tuberculosis and the like; and the Chinese medicine combination is preferably made into a paste which can be directly applied at traumatic injury parts, directly acts on focuses, quickly has effect and has good partial therapeutic effect on the wounds.
Description
Technical field
The present invention relates to the technology of pharmaceutical engineering field, relate in particular to a kind of Chinese medicine composition for the treatment of the horse traumatic injury and preparation method thereof.
Background technology
At present, China's horse keeping industry just grows stronger day by day, horse keeping and Equestrian competition sweep the country, and the contusion of horse, wound are that inevitably wound is self-evident to the health effect of horse.China horse is very slow with the veterinary drug production development, and the medicine of original creation is almost nil.Cure the symptoms, not the disease for Western medicine, easily produce the problems such as resistance and dependency, we turn on safe Chinese herbal medicine by sight.In addition, domestic field of veterinary, Chinese herbal medicine mainly be take powder, injection as main, and imprecise for the wound local efficacy, quality is unstable, and therefore developing a kind ofly has positive effect for the obvious Chinese medicine composition of wound local efficacy to treatment horses traumatic injury.
Summary of the invention
Technical problem to be solved by this invention is, overcoming prior art provides a kind of effective reduction toxic and side effects, instant effect, is difficult for developing immunity to drugs, effectively treat the traumatic injury of horse and the Chinese medicine composition and preparation method thereof of good treatment horse traumatic injury to the wound local efficacy.
In order to solve the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of the horse traumatic injury, wherein, described Chinese medicine composition comprises following raw medicinal material: Sanguis Draxonis, Olibanum, Myrrha, catechu, Os Draconis, Pyritum and Moschus.
The ratio of weight and number of the raw medicinal material in described Chinese medicine composition is preferably, Sanguis Draxonis 25-35 part, Olibanum 15-25 part, Myrrha 30-45 part, catechu 25-45 part, Os Draconis 12-28 part, Pyritum 12-28 part and Moschus 1-5 part.
The ratio of weight and number of the raw medicinal material in described Chinese medicine composition can also be more preferably, Sanguis Draxonis 28-30 part, Olibanum 18-22 part, Myrrha 39-41 part, catechu 29-41 part, Os Draconis 19-21 part, Pyritum 19-21 part and Moschus 1-3 part.
The ratio of weight and number of the raw medicinal material in described Chinese medicine composition again can be more preferably, 30 parts of Sanguis Draxonis, 20 parts of Olibanums, 40 parts of Myrrhas, 35 parts, catechu, 2 parts, 20 parts of Os Draconis, 20 parts of Pyritums and Moschus.
Described Chinese medicine composition can further include the Semen Persicae Flos Carthami, and ratio of weight and number is respectively 10～15 parts of Flos Carthami 8-12 parts of Semen Persicae.Be preferably 10 parts of 12 parts of Flos Carthami of Semen Persicae.
Described Chinese medicine composition can further include Rhizoma Corydalis, Resina Liquidambaris, Rhizoma Drynariae and Lignum Sappan, and ratio of weight and number is respectively Rhizoma Corydalis 15-25 part, Resina Liquidambaris 20-25 part, Rhizoma Drynariae 22-28 part and Lignum Sappan 10-15 part.Be preferably 12 parts of 20 parts of Rhizoma Corydalis, 23 parts of Resina Liquidambarises, 25 parts of Rhizoma Drynariae and Lignum Sappans.
The preparation method when dosage form of above-mentioned any one described Chinese medicine composition is unguentum is:
The dosage form of described Chinese medicine composition is unguentum, and described preparation method comprises the following steps,
(1) take by weight other raw medicinal materials except Moschus and grind into powder and be dipped in the Oleum sesami that parts by weight are 30-50 part, remove slag after seven days, the oil of getting it filled is standby;
(2) take the Colophonium that parts by weight are 80-120 part and be boiled into brown color degree of being with copper pot slow fire, add the medicine oil of step (1), then be heated to 100-150 ℃, keep 20-40 minute, put to room temperature, be semi-solid state standby;
(3) take by weight Moschus, grind into powder in the semi-solid medicament that adds step (2) and mix well, enter the bottle sealing standby, obtain the unguentum finished product.
The present invention provides again a kind of preparation method of Chinese medicine composition of above-mentioned any one treatment horse traumatic injury, and wherein: the dosage form of described Chinese medicine composition is unguentum, and described preparation method comprises the following steps,
(1) take by weight other raw medicinal materials except Moschus and grind into powder and be dipped in the Oleum sesami that parts by weight are 30-50 part, remove slag after seven days, the oil of getting it filled is standby;
(2) take the Colophonium that parts by weight are 80-120 part and be boiled into brown color degree of being with copper pot slow fire, add the medicine oil of step (1), then be heated to 100-150 ℃, keep 20-40 minute, put to room temperature, be semi-solid state standby;
(3) take by weight Moschus, grind into powder in the semi-solid medicament that adds step (2) and mix well, enter the bottle sealing standby, obtain the unguentum finished product.
The present invention also provides a kind of preparation method of Chinese medicine composition of above-mentioned any one treatment horse traumatic injury, and wherein: the dosage form of described Chinese medicine composition is unguentum, and its preparation method comprises the following steps:
(1) take by weight other raw medicinal materials except Olibanum, Myrrha, Os Draconis and Pyritum, add weight to be equivalent to the alcoholic solution of 2～5 times of got raw medicinal material weight summation, flood 24～48 hours;
(2) decoct the impregnation liquid 2～4 times of backflow above-mentioned steps (1), merge the alcoholic solution reclaimed after above-mentioned decoction refluxes, add 4～10 parts of triethanolamine, 8～12 parts of glycerol, obtain decoction liquor standby;
(3) take by weight Os Draconis and Pyritum, add weight to be equivalent to 3～6 alcoholic solution of aforementioned drug weight summation, flood after 48～72 hours and filter, filtrate for later use;
(4) take by weight Olibanum and Myrrha, be placed in water-bath, add 15～30 parts of sodium laurylsulfates, 12～28 parts, vaseline, 15～35 parts of vegetable oil are heated to fusing, stirring and emulsifying in stirring and evenly mixing the decoction liquor that adds while hot step (2) to prepare;
(5) in the solution that the filtrate prepared by step (3) adds above-mentioned steps (4) to prepare, stir 30～60 minutes, make unguentum.
Beneficial effect of the present invention: the present invention is made by pure Chinese medicinal herbs, and wide material sources, cost are low, and cure rate is high, and the medicine noresidue, have no side effect; The employing medicine that analgesic therapy, removing stasis to stop bleeding, detumescence suppuration, synthetism are cured the wound of invigorating blood circulation, reasonable recipe, can reach fast promote to dampen, the purpose of the healing of the traumatic injury such as suppurative wound and fracture, reunion of fractured tendons and bones, detumescence, pain relieving, suppuration, granulation promoting; The present invention can also be used for the treatment of the treatment after the ulcerations such as fistula and lymphoid tuberculosis, tuberculosis of breast simultaneously, has the effects such as good blood circulation promoting and blood stasis dispelling, detumescence suppuration; The preferential unguentum that adopts, can directly carry out administration to the traumatic injury position, through focus, instant effect is good to the local efficacy of wound.
The specific embodiment
The invention provides a kind of Chinese medicine composition for the treatment of the horse traumatic injury, wherein, described Chinese medicine composition comprises following raw medicinal material: Sanguis Draxonis, Olibanum, Myrrha, catechu, Os Draconis, Pyritum and Moschus.
The ratio of weight and number of the raw medicinal material in described Chinese medicine composition is preferably, Sanguis Draxonis 25-35 part, Olibanum 15-25 part, Myrrha 30-45 part, catechu 25-45 part, Os Draconis 12-28 part, Pyritum 12-28 part and Moschus 1-5 part.
The ratio of weight and number of the raw medicinal material in described Chinese medicine composition can also be more preferably, Sanguis Draxonis 28-30 part, Olibanum 18-22 part, Myrrha 39-41 part, catechu 29-41 part, Os Draconis 19-21 part, Pyritum 19-21 part and Moschus 1-3 part.
The ratio of weight and number of the raw medicinal material in described Chinese medicine composition again can be more preferably, 30 parts of Sanguis Draxonis, 20 parts of Olibanums, 40 parts of Myrrhas, 35 parts, catechu, 2 parts, 20 parts of Os Draconis, 20 parts of Pyritums and Moschus.
Described Chinese medicine composition can further include the Semen Persicae Flos Carthami, and ratio of weight and number is respectively 10～15 parts of Flos Carthami 8-12 parts of Semen Persicae.Be preferably 10 parts of 12 parts of Flos Carthami of Semen Persicae.
Described Chinese medicine composition can further include Rhizoma Corydalis, Resina Liquidambaris, Rhizoma Drynariae and Lignum Sappan, and ratio of weight and number is respectively Rhizoma Corydalis 15-25 part, Resina Liquidambaris 20-25 part, Rhizoma Drynariae 22-28 part and Lignum Sappan 10-15 part.Be preferably 12 parts of 20 parts of Rhizoma Corydalis, 23 parts of Resina Liquidambarises, 25 parts of Rhizoma Drynariae and Lignum Sappans.
The preparation method when dosage form of above-mentioned any one described Chinese medicine composition is unguentum is:
(1) take by weight other raw medicinal materials except Moschus and grind into powder and be dipped in the Oleum sesami that parts by weight are 30-50 part, remove slag after seven days, the oil of getting it filled is standby;
(2) take the Colophonium that parts by weight are 80-120 part and be boiled into brown color degree of being with copper pot slow fire, add the medicine oil of step (1), then be heated to 100-150 ℃, keep 20-40 minute, put to room temperature, be semi-solid state standby;
(3) take by weight Moschus, grind into powder in the semi-solid medicament that adds step (2) and mix well, enter the bottle sealing standby, obtain the unguentum finished product.
The present invention provides again a kind of preparation method of Chinese medicine composition of above-mentioned any one treatment horse traumatic injury, and wherein: the dosage form of described Chinese medicine composition is unguentum, and described preparation method comprises the following steps,
(1) take by weight other raw medicinal materials except Moschus and grind into powder and be dipped in the Oleum sesami that parts by weight are 30-50 part, remove slag after seven days, the oil of getting it filled is standby;
(2) take the Colophonium that parts by weight are 80-120 part and be boiled into brown color degree of being with copper pot slow fire, add the medicine oil of step (1), then be heated to 100-150 ℃, keep 20-40 minute, put to room temperature, be semi-solid state standby;
(3) take by weight Moschus, grind into powder in the semi-solid medicament that adds step (2) and mix well, enter the bottle sealing standby, obtain the unguentum finished product.
The present invention also provides a kind of preparation method of Chinese medicine composition of above-mentioned any one treatment horse traumatic injury, and wherein: the dosage form of described Chinese medicine composition is unguentum, and its preparation method comprises the following steps:
(1) take by weight other raw medicinal materials except Olibanum, Myrrha, Os Draconis and Pyritum, add weight to be equivalent to the alcoholic solution of 2～5 times of got raw medicinal material weight summation, flood 24～48 hours;
(2) decoct the impregnation liquid 2～4 times of backflow above-mentioned steps (1), merge the alcoholic solution reclaimed after above-mentioned decoction refluxes, add 4～10 parts of triethanolamine, 8～12 parts of glycerol, obtain decoction liquor standby;
(3) take by weight Os Draconis and Pyritum, add weight to be equivalent to 3～6 alcoholic solution of aforementioned drug weight summation, flood after 48～72 hours and filter, filtrate for later use;
(4) take by weight Olibanum and Myrrha, be placed in water-bath, add 15～30 parts of sodium laurylsulfates, 12～28 parts, vaseline, 15～35 parts of vegetable oil are heated to fusing, stirring and emulsifying in stirring and evenly mixing the decoction liquor that adds while hot step (2) to prepare;
(5) in the solution that the filtrate prepared by step (3) adds above-mentioned steps (4) to prepare, stir 30～60 minutes, make unguentum.
The pharmacology of described each component is as follows:
Sanguis Draxonis: have another name called blood outstanding person, Sanguis Draxonis, blood agglomeration, Sanguis Draxonis, sea wax, dragon's blood etc.Sweet in the mouth, salty, property is flat.Enter the heart, liver, spleen channel.Promoting blood circulation to remove blood stasis, analgesic therapy, hemostasia and promoting granulation, sore.Cure mainly congestion amenorrhea, dysmenorrhea, postpartum stagnation; The lump in the abdomen mass in the abdomen, breast ventral spine pain; Traumatic injury, congestion swells and ache; Traumatic hemorrhage, ulcer being unable to heal.Tang Materia Medica: main the five internal organs pathogen, leukorrhagia, pain relieving, removing mass blood, gold creation meat.
Olibanum: have another name called smoked Lu Xiang, horse hair is fragrant, nipple is fragrant, the perfume (or spice) that collapses, it pool is fragrant, Moller is fragrant, many gals Luo Xiang etc.Acrid in the mouth, hardship, warm in nature.Enter the heart, liver, spleen channel.Invigorate blood circulation, circulation of qi promoting, pain relieving, detumescence and promoting granulation.For traumatic injury, skin infection carbuncle, congestion blocks all diseases etc." not Lu ": treat the edema due to wind pathogen poison swollen, remove bad odor.Treat the urticaria poison of itching.Supplement to the Herbal: treat deaf, the apoplexy locked mouth, married woman's vim and vigour, can send out wine, manages air-cooledly, stops large intestine and let out Bleach, treats all skin ulcers and make internal diabetes.
Myrrha: have another name called myrrh, bright Myrrha.Bitter in the mouth, suffering, property is flat.Enter liver, spleen, the heart, kidney channel.Promoting blood circulation and stopping pain, detumescence and promoting granulation.Cure mainly breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, lump in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain etc.
Catechu: another name CATECHU, Catechu, gambier.Bitter in the mouth, puckery, cold nature.Return lung meridian.But removing heat-phlegm for oral administration, for the cough due to lung-heat; External can be invigorated blood circulation and be cured the wound, hemopoietic granulation promoting, removing dampness sore.For controlling wound congestive edema, hemorrhage and carbuncle sore, eczema, ulcerative gingivitis etc.
Os Draconis: have another name called Lu Hu and lose life, that gal bone, Os Draconis, Os Draconis (calcined), five OS DRACONISs, green grass or young cropsization Os Draconis, OS DRACONIS, Os Draconis.Sweet in the mouth, puckery, property is flat.Enter the heart, liver, kidney, large intestine channel.Tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, and spontaneous sweating, the seminal emission stranguria with turbid discharge, telling nosebleed and having blood in stool, bleeding not during menses, the dysentery proctoptosis, ulcer does not close up etc. for a long time.
Pyritum: acrid in the mouth, property is flat, has eliminating stasis to stop pain, and the effect of reunion of fractured tendons and bones, cure mainly traumatic injury, the tendon breaking fracture, blood stasis pain, gather, goiter, skin infection, the cards such as scald, " Japan hanako materia medica ": evacuation of pus, repercussive blood, reuniting the fractured tendons and bones, the rear blood heresy of managing property, feel at ease, and spasmolytic is throbbed with fear.With wine mill clothes.
Moschus: have another name called river deer, Moschus, umbilicus perfume (or spice), four flavors are smelly, smelly son, cured son, fragrant, the living perfume of hearty cord, MOSCHUS etc.Hot, warm, nontoxic, the bitter in the mouth of property.Enter the heart, spleen, Liver Channel, the refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain, the lower tire of hastening parturition.The function of having one's ideas straightened out, warding off dirty, dredging collateral, scattered silt is arranged.Cure mainly excess syndrome of stroke coma, anemofrigid-damp arthralgia, apoplexy, syncope due to accumulation of phlegm, infantile convulsion, attacked by pestiferous factors unhappiness, trusted subordinate's sudden pain, traumatic injury, swollen ulcer drug, difficult labour, stillborn fetus, retention of placenta etc.
Semen Persicae: another name Radix Fici Hirtae core, almond core, large Semen Persicae.Bitter in the mouth, sweet, property is flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.For amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation, blood stasis symptom, lung abscess, acute appendicitis etc.The special medicine closed for blood stasis blood.Bitter to let out stagnant blood, sweet with tissue regeneration promoting blood." medicine justice ": Semen Persicae, bitter in the mouth can rush down heat in blood, and the body profit can be grown dryness of the intestine.If it is multiplex that gross weight grinds, walk Liver Channel, main broken blood-retention, water, and pain all over month by month, extremity wood numbness, left hemiplegia, left sufficient patient, relax through the promoting the circulation of blood of invigorating blood circulation with it, the merit that eliminating blood stasis to promote regeneration of blood is arranged, if few use is mashed in peeling, enter large intestine, controlling blood depletion just closes, the dry dyschezia of blood, with its make moist removing heat from blood and blood, have relieving accumulation of pathogens to lead to stagnant power.
Flos Carthami: claim again Flos Carthami, thorn Flos Carthami, Flos Carthami, golden red flower.Acrid in the mouth, warm in nature.GUIXIN, Liver Channel.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Cure mainly amenorrhea due to stagnation of blood, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury, the macule of the swollen blood stasis of heat, puerperal blood faints, the stagnant stomachache of the stasis of blood, obstruction of qi in the chest and cardialgia, accumulation of blood, traumatic injury congestive edema, arthralgia, paralysis due to windstroke, macular eruption being dark-purple etc." medicine justice ": Flos Carthami, kind tonneau passages through which vital energy circulates, be gas medicine in blood, can rush down and can mend, and wonderful justice is respectively arranged.If multiplex three, four money, too hot temperature, wander away blood.With Lignum Sappan removing blood stasis blood, to close Cortex Cinnamomi and stimulate the menstrual flow and close, assistant is returned, Chinese herbaceous peony is controlled all over or breast abdomen pricking caused by the stagnation of QI and blood, and this its row is led and invigorates blood circulation also.If use less seven, eight minutes, with dispersing liver-energy, to help the sea of blood, the void of enriching blood greatly, this its adjust smooth and and blood also; If, only with two, three minutes, enter the heart to join painstaking effort, dismiss heart channel pathogenic fire, make the blood mediation, this its nourishing and hemopoietic are also; The justice of component number, meagre.
Rhizoma Corydalis: another name: Rhizoma Corydalis, corydalis tuber, rhizoma corydalis, Rhizoma Corydalis.Acrid in the mouth, hardship, warm in nature.Return spleen, heart channel.Invigorate blood circulation, circulation of qi promoting, pain relieving.For all pain diseases of stagnation of QI-blood, anesthesia, calmness, relieving convulsion is coughed etc.Cure mainly all pains of trusted subordinate's waist knee joint; Menoxenia; Lump in the abdomen; Metrorrhagia; Puerperal blood faints; Lochiorrhea; Traumatic injury.Analgesia, calmness, syngignoscism are arranged." detailed outline ": invigorate blood circulation, promoting the circulation of QI, pain relieving, diuresis.Rhizoma Corydalis, the stagnation of QI in the energy promoting the circulation of blood, stasis in gas, thus specially control upper and lower all pains all over the body, among using, simply fantastic." Bencao Jingshu ": Rhizoma Corydalis, Wen Zeneng and smooth, and freely gas is capable; Xin Zeneng moistens and wanders away, and the blood of wandering away is lived.Blood lively atmosphere row, thus can main removing blood stasis and puerperal all cause of disease blood person of doing." book on Chinese herbal medicine is looked for the truth ": Rhizoma Corydalis, no matter be that blood is gas, amass and loose person, taking this power can be sensible, warm in nature with it, and in QI and blood, can manage it can be smooth, and acrid in the mouth can moisten and can fall apart in QI and blood, and so manage upper and lower all pains all over the body, the merit of often walking alone is many.
Resina Liquidambaris: have another name called that Resina Liquidambaris, maple fat, white glue, Folium Symplocoris Caudatae, glue are fragrant, uncle is according to Ga Er (mongolian medicine name) etc.Acrid in the mouth, hardship, property is flat.Return spleen, lung, Liver Channel.Expelling wind and activating blood circulation, removing toxic substances pain relieving, hemostasis, granulation promoting.For carbuncle, skin ulcer rash, scrofula, toothache, arthralgia pain, paralysis, spit blood, epistaxis, spitting of blood, traumatic hemorrhage, chapped skin etc.
Rhizoma Drynariae: have another name called: hair cyrtomium fortunei, drynaria baronii, hair Rhizoma Zingiberis Recens, monkey Rhizoma Zingiberis Recens, the broken benefit of stone, flying apsaras Mus, Niu Feilong, sudden wind, moth grass etc.Bitter in the mouth, warm in nature.Return liver, kidney channel.The kidney invigorating bone strengthening, continue and hinder pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; The external treatment alopecia areata, vitiligo.
Lignum Sappan: have another name called Soviet Union's a tree, used in making timber for boats, the Soviet side, lignum sappan, lowland swamp wood, palm fibre wood, Ramulus et Folium Bischofiae Javanicae, red bavin etc.Sweet in the mouth, salty, hot, property is flat.GUIXIN, Liver Channel.Invigorate blood circulation and cure the wound, blood stasis dispelling stimulates the menstrual flow.For traumatic injury, the fracture injury of tendon and muscle, the stasis of blood is stagnant to swell and ache, amenorrhea due to stagnation of blood, postpartum stagnation stomachache, dysmenorrhea, trusted subordinate's pain, carbuncle sore tumefacting virus etc.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how the application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
Embodiment 1:
A kind of Chinese medicine composition for the treatment of the horse traumatic injury comprises following raw medicinal material: Sanguis Draxonis 30g, Olibanum 20g, Myrrha 40g, catechu 35g, Os Draconis 20g, Pyritum 20g and Moschus 2g.
Preparation method comprises the following steps:
(1) other raw medicinal materials that take by weight except Moschus are ground into powder in the Oleum sesami that is dipped into 50g, after seven days, remove slag, and the oil of getting it filled is standby;
(2) Colophonium that takes 100g is boiled into brown color degree of being with copper pot slow fire, adds the medicine oil of step (1), then is heated to 120 ℃, keeps 30 minutes, puts to room temperature, is semi-solid state standby;
(3) take by weight Moschus, grind into powder in the semi-solid medicament that adds step (2) and mix well, enter the bottle sealing standby, obtain the unguentum finished product.
Embodiment 2:
A kind of Chinese medicine composition for the treatment of the horse traumatic injury comprises following raw medicinal material: Sanguis Draxonis 28g, Olibanum 22g, Myrrha 41g, catechu 30g, Os Draconis 19g, Pyritum 19, Moschus 3g, Semen Persicae 12g Flos Carthami 10g.
The dosage form of Chinese medicine composition is unguentum, and its preparation method comprises the following steps:
(1) take by weight other raw medicinal materials except Olibanum, Myrrha, Os Draconis and Pyritum, add weight to be equivalent to the alcoholic solution of 4 times of got raw medicinal material weight summation, flood 48 hours;
(2) decoct the impregnation liquid 3 times of backflow above-mentioned steps (1), merge the alcoholic solution reclaimed after above-mentioned decoction refluxes, add triethanolamine 8g, glycerol 10g, obtain decoction liquor standby;
(3) take by weight Os Draconis and Pyritum, add weight to be equivalent to 5 alcoholic solution of aforementioned drug weight summation, flood after 72 hours and filter, filtrate for later use;
(4) take by weight Olibanum and Myrrha, be placed in water-bath, add sodium laurylsulfate 25g, vaseline 20g, vegetable oil 35g is heated to fusing, stirring and emulsifying in the decoction liquor that stirring and evenly mixing also adds step (2) to prepare while hot;
(5) in the solution that the filtrate prepared by step (3) adds above-mentioned steps (4) to prepare, stir 50 minutes, make unguentum.
Embodiment 3:
A kind of Chinese medicine composition for the treatment of the horse traumatic injury comprises following raw medicinal material: Sanguis Draxonis 30g, Olibanum 18g, Myrrha 39g, catechu 41g, Os Draconis 21g, Pyritum 20g, Moschus 2g, Rhizoma Corydalis 20g, Resina Liquidambaris 23g, Rhizoma Drynariae 25g and Lignum Sappan 12g.
Preparation method comprises the following steps:
(1) other raw medicinal materials that take by weight except Moschus are ground into powder in the Oleum sesami that is dipped into 45g, after seven days, remove slag, and the oil of getting it filled is standby;
(2) Colophonium that takes 120g is boiled into brown color degree of being with copper pot slow fire, adds the medicine oil of step (1), then is heated to 150 ℃, keeps 40 minutes, puts to room temperature, is semi-solid state standby;
(3) take by weight Moschus, grind into powder in the semi-solid medicament that adds step (2) and mix well, enter the bottle sealing standby, obtain the unguentum finished product.
Embodiment 4:
A kind of Chinese medicine composition for the treatment of the horse traumatic injury, comprise following raw medicinal material: Sanguis Draxonis 35g, Olibanum 25g, Myrrha 35g, catechu 25g, Os Draconis 15g, Pyritum 15, Moschus 5g, Semen Persicae 15g, Flos Carthami 8g, Rhizoma Corydalis 15g, Resina Liquidambaris 20g, Rhizoma Drynariae 23g and Lignum Sappan 15g.
The dosage form of Chinese medicine composition is unguentum, and its preparation method comprises the following steps:
(1) take by weight other raw medicinal materials except Olibanum, Myrrha, Os Draconis and Pyritum, add weight to be equivalent to the alcoholic solution of 5 times of got raw medicinal material weight summation, flood 48 hours;
(2) decoct the impregnation liquid 3 times of backflow above-mentioned steps (1), merge the alcoholic solution reclaimed after above-mentioned decoction refluxes, add triethanolamine 10g, glycerol 12g, obtain decoction liquor standby;
(3) take by weight Os Draconis and Pyritum, add weight to be equivalent to 6 alcoholic solution of aforementioned drug weight summation, flood after 60 hours and filter, filtrate for later use;
(4) take by weight Olibanum and Myrrha, be placed in water-bath, add sodium laurylsulfate 28g, vaseline 25g, vegetable oil 32g is heated to fusing, stirring and emulsifying in the decoction liquor that stirring and evenly mixing also adds step (2) to prepare while hot;
(5) in the solution that the filtrate prepared by step (3) adds above-mentioned steps (4) to prepare, stir 60 minutes, make unguentum.
Acute toxicity test:
60 of application NIH mices, the SPF level, male and female half and half, body weight 16～22g, carry out acute toxicity testing.Mice is divided into two groups at random, i.e. the administration group 2 of the administration group 1 of the Chinese medicine composition of the administration embodiment of the present invention 1 and the Chinese medicine composition of the administration embodiment of the present invention 4, and before experiment, fasting is 12 hours.Administration group 1 and administration group 2 directly spread upon the Chinese medicine preparation of embodiments of the invention 1 and embodiment 4 preparations on mice extremity or skin of abdomen respectively, administration in 1 day 2 times, delivery time 6 hours, after administration, Continuous Observation is 14 days, and records toxic reaction and the death toll of mice.Experimental result shows: after administration, mice has no notable difference, experiment Continuous Observation 14 days, the mice overall health of patients, ingest, drinking-water, body weight gain is all normal.Therefore Chinese medicine acute toxicity of the present invention is low, clinical drug safety.
Clinical trial:
Chinese medicine composition avirulence of the present invention, directly smear or paste affected part and get final product, easy to use, direct effect affected part, instant effect.For fresh wound, after general Surgery Treatment, can use the mastic of embodiment 1 or embodiment 2 prescriptions to be coated in flap coverage on gauze, every 2 days, change dressings once; For suppurative wound, wound surface rinses with 0.1% potassium permanganate solution, wraps up after then can smearing the ointment of embodiment 1 or embodiment 2 prescriptions, within every 2 days, changes dressings once; For fistula, first with hydrogen peroxide, rinse fistula, immerse meche after then the mastic of embodiment 1 or embodiment 2 prescriptions being melted, then meche is filled in fistula, within every 2 days, change dressings once; For traumatic injury such as fracture, the paste application that can directly the prescription of embodiment 3 or embodiment 4 be made is to affected part, the paste application that also prescription of embodiment 3 or embodiment 4 can be made is to flap coverage on gauze, if during extremity fracture, to fracture site implement reduction, pinch flat broken bone, the fracture end contact is reached reset or para-position after paste unguentum, then fix with clamping plate or plaster bandage.During application, Chinese medicine composition of the present invention directly can be smeared or pasted in affected part by per kilogram of body weight 0.4-0.6g crude drug; According to teenager horsemanship training base, Qingdao and Ao Shanwei stud-farm, Qingdao statistical data are shown, the prescription of embodiment 1 or embodiment 2 is obvious especially and instant effect for new and old wound, contusion, suppurative wound and fistula texts, the prescription of embodiment 3 or embodiment 4 is obvious especially and instant effect for the miscellaneous fracture texts, general continuous use can be cured various traumatic injury or the wounds such as contusion, fresh wound, suppurative wound and fracture in 5-60 days, treatment time is short, clinical cure rate reaches 97%, and cure rate is high.
Model case 1
Teenager horsemanship training base, Qingdao
In trail riding, due to horse, when changing lower limb, having pedaled empty falls down, perhaps because the intention etc. that the horseman commands mistake or horses to misread the horseman causes wrestling, above-mentioned accident usually causes fracture or the damages such as horses extremity or rib, after fracture occurs, ill domestic animal has an intense pain, the normal perspiration in after elbow or burst inboard.During bone splits, tenderness appears.Affected part swelling, after 24 hours, swelling reaches peak.Suffering limb can not be bent and stretched, and limping or three limbs bound forward.Due to swelling and fracture site displacement, the limbs distortion appears.During full fracture, abnormal movement, appear in movable its distal end portion, at non-joint part, joint sample activity occurs, and can hear or feel the crunch of bone stump.X-ray takes the photograph sheet or perspective is made a definite diagnosis.
This training base is successively accepted 16 example fracture horses, wherein 11 routine extremity open fractures, 5 routine extremity and the non-open fractures of rib for medical treatment year August in May, 2012 to 2012.According to the horses situation, adopted respectively the Chinese medicine composition of the embodiment of the present invention 3 and the Chinese medicine composition of the embodiment of the present invention 4, within every 2 days, change dressings once; Result is: wherein 5, after administration 15-25 days, observe respectively, and suffer from horse and all fully recover; Wherein 4, after successive administration 25-35 days, observe respectively, suffer from horse and all fully recover; Wherein 7, after successive administration 35-42 days, observe respectively, suffer from horse and all fully recover.
Model case 2
Ao Shanwei stud-farm, Qingdao
This stud-farm is successively accepted 8 examples for medical treatment year August in May, 2012 to 2012 and is caused the wound horses because of frightened or run etc., 3 suppurative wounds wherein, 5 fresh wounds.Suppurative wound is fresh wound because of after antibacterial infects, the inflammation of wound section, swelling, heat, pain, in wound, slough liquefaction forms pus and flows out from wound.Fresh wound horses are ligament, the muscle of extremity and breast abdominal part position, the wound of tendon, skin is imperfect, the partial skin tissue has obvious scar, skin breakdown and external haemorrhage, and amount of bleeding is more, wound splits obviously, sharp ache, tissue injury is serious, and wound surface is not whole, without the joint dislocation, the osteocomma avulsion of juxtra-articular skeleton appears in part.According to the horses situation, adopted respectively the Chinese medicine composition of the administration embodiment of the present invention 1 or the Chinese medicine composition of the embodiment of the present invention 2, within every 2 days, change dressings once; Result is: observe after administration 5-15 days respectively, suffer from horse and all fully recover.
All above-mentioned these intellectual properties of primary enforcement, do not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above, be only preferred embodiment of the present invention, is not the present invention to be done to the restriction of other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not break away from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (3)
1. a Chinese medicine composition for the treatment of the horse traumatic injury, it is characterized in that, the ratio of weight and number of the raw medicinal material in described Chinese medicine composition is, Sanguis Draxonis 25-35 part, Olibanum 15-25 part, Myrrha 30-45 part, catechu 25-45 part, Os Draconis 12-28 part, Pyritum 12-28 part, Moschus 1-5 part, 10～15 parts, Semen Persicae, Flos Carthami 8-12 part, Rhizoma Corydalis 15-25 part, Resina Liquidambaris 20-25 part, Rhizoma Drynariae 22-28 part and Lignum Sappan 10-15 part;
The dosage form of described Chinese medicine composition is unguentum, and its preparation method comprises the following steps,
(1) take by weight other raw medicinal materials except Moschus and grind into powder and be dipped in the Oleum sesami that parts by weight are 30-50 part, remove slag after seven days, the oil of getting it filled is standby;
(2) take the Colophonium that parts by weight are 80-120 part and be boiled into brown color degree of being with copper pot slow fire, add the medicine oil of step (1), then be heated to 100-150 ℃, keep 20-40 minute, put to room temperature, be semi-solid state standby;
(3) take by weight Moschus, grind into powder in the semi-solid medicament that adds step (2) and mix well, enter the bottle sealing standby, obtain the unguentum finished product.
2. the Chinese medicine composition for the treatment of as claimed in claim 1 horse traumatic injury, it is characterized in that: the ratio of weight and number of the part material medical material in described Chinese medicine composition is, Sanguis Draxonis 28-30 part, Olibanum 18-22 part, Myrrha 39-41 part, catechu 29-41 part, Os Draconis 19-21 part, Pyritum 19-21 part and Moschus 1-3 part.
3. the Chinese medicine composition for the treatment of as claimed in claim 1 horse traumatic injury is characterized in that: the ratio of weight and number of the part material medical material in described Chinese medicine composition is, 30 parts of Sanguis Draxonis, 20 parts of Olibanums, 40 parts of Myrrhas, 35 parts, catechu, 2 parts, 20 parts of Os Draconis, 20 parts of Pyritums and Moschus.
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| CN101919946A (en) * | 2009-06-17 | 2010-12-22 | 芦根虎 | Plaster for treating bone fracture |
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| CN1165011A (en) * | 1996-12-16 | 1997-11-19 | 刘彦如 | Enternal use adhesive plaster for treatment of rheumatism |
| CN101919946A (en) * | 2009-06-17 | 2010-12-22 | 芦根虎 | Plaster for treating bone fracture |
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Inventor after: Zhang Jianjun Inventor after: Zou Zhigang Inventor after: Rong Meijie Inventor after: Zou Jingqing Inventor after: Guo Haipeng Inventor after: Li Chengxiu Inventor before: Zhang Jianjun Inventor before: Zou Zhigang Inventor before: Zhang Zhipeng Inventor before: Rong Meijie Inventor before: Zhang Xiaojun |
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Address after: 266221 No. 23 tobacco green road, Qingdao, Shandong, Jimo Patentee after: Qingdao Federer prosperous biological Polytron Technologies Inc Address before: 266200, No. 57, Wenhua Road, Jimo, Shandong, Qingdao province (South Gate Village) Patentee before: Qingdao Deray Junfa Biologictechnology Co., Ltd. |