CN105232667A - External use Chinese herba preparation for treatment of herpes zoster syndrome and preparation method thereof - Google Patents
External use Chinese herba preparation for treatment of herpes zoster syndrome and preparation method thereof Download PDFInfo
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- CN105232667A CN105232667A CN201510843894.5A CN201510843894A CN105232667A CN 105232667 A CN105232667 A CN 105232667A CN 201510843894 A CN201510843894 A CN 201510843894A CN 105232667 A CN105232667 A CN 105232667A
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Abstract
The invention discloses an external use Chinese herba preparation for treatment of a herpes zoster syndrome and a preparation method thereof. The external use Chinese herba preparation is prepared from, by weight, 20-70 g of gamboge, 10-50 g of realgar, 5-25 g of dried alum, 10-50 g of coptis chinensis, 0.5-1.5 g of musk and 1900-2100 ml of 75%-95% ethyl alcohol. The effective medicinal compositions are prepared into solvent to be applied to wounded parts. The external use Chinese herba preparation has a special effect on treatment of viral diseases such as herpes zoster, ulcer carbuncle and mosquito injuries, medicine can go deep into subcutaneous tissue to kill viruses, the medicine can take effect quickly, the course of treatment is short, the treatment rate is high, and the effective rate reaches 100%.
Description
Technical field
The present invention relates to and a kind ofly treat Chinese medicine for outer use of herpes zoster disease and preparation method thereof.
Technical background
Herpes zoster is the acute skin mucosa infection disease caused by varicella zoster virus.After viral infection with latent form long-term existence in the ganglionic cell of spinal nerves or cranial nerve, after being activated by some factor, virus arrives skin from one or several neuroganglion along corresponding peripheral nerve, causes recurrent infection, i.e. herpes zoster.Clinically with occur suddenly, along the herpes of neural zonal distribution, one-sided distribution, dense clusters for feature, pain is obvious.Clinical herpes zoster, be main mainly with intravenous drip acyclovir and vidarabine, cytosine arabinoside antiviral therapy, and be aided with intramuscular injection interferon, curative effect is slow, side effect is large.
Traditional Chinese medical science Chinese medicine for outer use treatment herpes zoster is effective, and short treating period, cure rate is high, side effect is little.
Summary of the invention
The technical problem to be solved in the present invention is to provide the Chinese medicine for outer use and preparation method thereof of a kind of instant effect, short treating period, treatment herpes zoster disease that cure rate is high.
For solving the problems of the technologies described above, the present invention is made up of the pharmacodynamic raw materials of following weight portion: Resina garciniae 20-70g, Realgar 10-50g, dried Alumen 5-25g, Rhizoma Coptidis 10-50g, Moschus 0.5-1.5g, 75-95% ethanol 1900-2100ml.
As optimal way, be made up of the pharmacodynamic raw materials of following weight portion: Resina garciniae 40-60g, Realgar 20-40g, dried Alumen 10-20g, Rhizoma Coptidis 20-40g, Moschus 0.8-1.2g, 80-95% ethanol 1950-2050ml.
More preferably be made up of the pharmacodynamic raw materials of following weight portion: Resina garciniae 50g, Realgar 30g, dried Alumen 15g, Rhizoma Coptidis 30g, Moschus 1g, 90-95% ethanol 2000ml.
Preparation method of the present invention comprises the following steps:
A, take Resina garciniae, Realgar, dried Alumen, Rhizoma Coptidis, Moschus by formula ratio, be ground into the fine powder of below 100 orders respectively;
B, the alcoholic solution 1900-2100ml that the Rhizoma Coptidis crushed is added, soaking and stirring 5-7 days, filters medicinal residues for subsequent use;
C, the powder of Resina garciniae, Realgar, dried Alumen is fully mixed after, put into the alcoholic solution soaking and stirring of soaking Rhizoma Coptidis, after 3 days, filter out medicinal residues;
D, in the solution filtering out medicinal residues, add Moschus powder and stir evenly, sterilizing bottling is the external preparation for the treatment of herpes zoster.
Using method of the present invention: Chinese medicine preparation is embrocated affected part 3-10 times every day by patient.
In formula of the present invention, Resina garciniae have another name called beautiful yellow, the moon is yellow, nature and flavor acid, puckery, poisonous; Detumescence, removing toxic substances, hemostasis, parasite killing; Cure mainly swollen ulcer drug, stubborn dermatitis malignant boil, bleeding due to trauma, ulcerative gingivitis, decayed tooth, burn.Qing Dynasty ZHAO Xue-Min supplementary Amplifications of the Compendium of Materia Medica meaning: control carbuncle, hemostasis removing toxic substances, holds back incised wound, also can parasite killing, and control cutter axe lifeless thing and injure burn and scald, bamboo wood thrusts meat, all clear skin ulcers.Modern medicine study proves, Resina garciniae anti-inflammation, and the diseases such as granulation promoting exceedes skin ulcer, external curing skin infection have specially good effect; " dermatitis research " is called: Resina garciniae externally treating herpes zoster and herpes simplex have good efficacy.Experimental result preliminary proof, Resina garciniae has direct repression to herpesvirus, and local topical can kill herpesvirus at short notice, is the monarch drug in formula of the present invention.Realgar, another name gold stone, dark yellow, waist Huang, red orpiment, orpiment, acrid in the mouth is bitter, warm in nature, poisonous; Dampness is detoxified, sterilizing and itch-relieving; Cure mainly malaria cold and heat, the disease due to latent summer-heat pathogen dysentery, worm disease suffer from abdominal pain, scabies malignant boil, the diseases such as worm venom.Dried Alumen, nature and flavor are sour and astringent, poisonous, enter lung, taste, large intestine channel; Expectorant, dampness, antidiarrheal, hemostasis, removing toxic substances, parasite killing; Control epilepsy, sore throat, remorse saliva is stopped up very, and hepatitis, jaundice, general edema with yellowish skin, taste-blindness rate, uterine prolapse, leucorrhea, dysentery, epistaxis, aphtha of the mouth and tongue, skin ulcer hemorrhoid scabies, water, fire, insect bite, forge with granulation promoting but water.Rhizoma Coptidis, has another name called Wang Lian, Zhi Lian, nature and flavor bitter cold, enters the heart, spleen, stomach, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication; For damp and hot feeling of fullness, vomiting, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, and conjunctival congestion acid regurgitation, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated, burn and scald etc.Realgar, dried Alumen, Rhizoma Coptidis are the ministerial drugs in the invention of this formula, and three share, and effectively can kill herpesvirus by helping monarch drug, can respectively play a role according to drug effect again.Realgar is exactly the key agents for the treatment of scabies malignant boil, worm venom in recipe in many ancient times; Dried Alumen plays effect of granulation promoting, convergence, removing toxic substances in formula of the present invention; Rhizoma Coptidis parasite killing, dampness, pathogenic fire purging, removing toxic substances, with monarch drug compatibility, strengthen drug effect, bring out the best in each other.Moschus, has another name called Moschus, and umbilicus is fragrant, and fragrant umbilicus, property and flavor of peppery and warm, enters the heart, spleen, Liver Channel.To have one's ideas straightened out refreshment, promoting blood circulation to restore menstrual flow, pain relieving is hastened parturition; For excess syndrome of stroke coma, no matter constipation due to cold pathogen, heat-blockage, all effectively; Treatment of ulcer toxic swelling, laryngopharynx swelling and pain, blood stasis amenorrhea, note of the ancient Chinese abdominal mass, trusted subordinate's sudden pain, traumatic injury, the cards such as anemofrigid-damp arthralgia are the adjuvant drugs in the invention of this formula.The property that Moschus is walked to alter is very strong, opens away and alters, can the stasis of blood in promoting the circulation of blood stagnant, the heap soil or fertilizer over and around the roots of opening meridians is held back, and stimulate the menstrual flow removing obstruction for relieving pain, and the medicine of helping the monarch and his subjects goes directly focus, kills banded virus.Ethanol, sweet, bitter, pungent, warm, enter the heart, liver, lung, stomach warp, promoting blood circulation, resisting cold gas, controls wind and cold arthralgia pain, and muscle arteries and veins contraction is anxious, the thoracic obstruction, trusted subordinate's cold type of pain.Chinese medicine is thought, the capable medicine gesture of ethanol energy of high concentration, thoroughly skin, is to make medicine in the invention of this formula.The monarch and his subjects' adjuvant drug, through the immersion of ethanol, can soak into skin, antalgesic-antipruritic, effectively kills subcutaneous banded virus.Full side's compatibility is reasonable, evident in efficacy.
The present invention has specially good effect to viral dermatosis such as treatment herpes zoster, carbuncle skin infection, mosquito wound etc., and medicine deep and thoroughly subcutaneously can kill virus, and Chinese medicine preparation is embrocated affected part 3-10 times every day by patient, the same day pain relief, herpes reduces, and general patient fully recovered in 7 days, and severe one all exceedes in January.Its instant effect, short treating period, controls that to exceed rate high, effective percentage 100%.
Detailed description of the invention:
Embodiment 1
Resina garciniae 20g, Realgar 50g, dried Alumen 5g, Rhizoma Coptidis 50g, Moschus 0.5g, 95% ethanol 1900ml.
Embodiment 2
Resina garciniae 70g, Realgar 10g, dried Alumen 25g, Rhizoma Coptidis 10g, Moschus 1.5g, 75% ethanol 2100ml.
Embodiment 3
Resina garciniae 40g, Realgar 40g, dried Alumen 10g, Rhizoma Coptidis 40g, Moschus 0.8g, 95% ethanol 1950ml.
Embodiment 4
Resina garciniae 60g, Realgar 20g, dried Alumen 20g, Rhizoma Coptidis 20g, Moschus 1.2g, 80% ethanol 2050ml.
Embodiment 5
Resina garciniae 50g, Realgar 30g, dried Alumen 15g, Rhizoma Coptidis 30g, Moschus 1g, 95% ethanol 2000ml.
Chinese medicine for outer use of the present invention, prepare according to the following steps:
A. take Resina garciniae, Realgar, dried Alumen, Rhizoma Coptidis, Moschus by formula ratio, be ground into the fine powder of below 100 orders;
B. the Rhizoma Coptidis crushed is added the ethanol 1900-2100ml soaking and stirring 5-7 days of 75-95%, filter medicinal residues for subsequent use;
C., after the powder of Resina garciniae, Realgar, dried Alumen fully being mixed, put into the alcoholic solution soaking and stirring of soaking Rhizoma Coptidis, after 3 days, filter out medicinal residues;
D. in the solution filtering out medicinal residues, add Moschus powder and stir evenly, sterilizing bottling is the external preparation for the treatment of herpes zoster.
The using method of invention formulation, Chinese medicine preparation is embrocated affected part 3-10 times every day by patient.The same day pain relief, herpes reduces, general patient 7 days recovery from illness, and severe one is fullyed recover from an illness in 2 weeks and exceeded, and the patient that skin ulcer face is comparatively large, sick time is longer fully recovers for 4 weeks.
Chinese medicine for external application of the present invention, to 100 routine Patients with Herpes Zosters, carries out clinical effective rate observation, effective percentage 100%.
Clinical efficacy result is as follows:
1st group, within herpes zoster area 5cm 30 example, embrocate affected part every day 3-6 times, the same day pain relief, herpes reduction of area is little; By the 5th day, 18 routine herpess are had to disappear; To the 7th day, other 12 routine herpess disappeared.
2nd group, herpes zoster area 5-10cm patient 35 example, embrocate affected part every day 6-8 times, the same day pain relief, herpes reduction of area is little; 7th, 11 routine herpess are had to disappear; 11st, 15 routine herpess are had again to disappear; To the 14th day, other 9 routine herpess disappeared.
3rd group, herpes zoster area be greater than 10cm patient 30 example, embrocate affected part every day 8-10 times, the same day pain relief, herpes reduction of area is little; In two weeks, 13 routine herpess disappear; 3rd week, 11 routine herpess are had to disappear; 4th week, other 6 routine herpess all disappear.
Above efficacy result, illustrates formula Chinese medicine for external application effective percentage 100% of the present invention.
Claims (5)
1. treat a Chinese medicine for outer use for herpes zoster disease, the raw material composition and the weight proportion thereof that it is characterized in that making this Chinese medicine for outer use effective ingredient are: Resina garciniae 20-70g, Realgar 10-50g, dried Alumen 5-25g, Rhizoma Coptidis 10-50g, Moschus 0.5-1.5g, 75-95% ethanol 1900-2100ml.
2. the Chinese medicine for outer use of the treatment herpes zoster disease according to right 1, the raw material composition and the weight proportion thereof that it is characterized in that making this Chinese medicine for outer use effective ingredient are: Resina garciniae 40-60g, Realgar 20-40g, dried Alumen 10-20g, Rhizoma Coptidis 20-40g, Moschus 0.8-1.2g, 80-95% ethanol 1950-2050ml.
3. the Chinese medicine for outer use of the treatment herpes zoster disease according to right 1, the raw material composition and the weight proportion thereof that it is characterized in that making this Chinese medicine for outer use effective ingredient are: Resina garciniae 50g, Realgar 30g, dried Alumen 15g, Rhizoma Coptidis 30g, Moschus 1g, 90-95% ethanol 2000ml.
4. the preparation method of the Chinese medicine for outer use of the treatment herpes zoster disease according to any one of right 1-3, its feature comprises the following steps:
A, take Resina garciniae, Realgar, dried Alumen, Rhizoma Coptidis, Moschus by formula ratio, be ground into the fine powder of below 100 orders respectively;
B, the alcoholic solution 1900-2100ml that the Rhizoma Coptidis crushed is added, soaking and stirring 5-7 days, filters medicinal residues for subsequent use;
C, the powder of Resina garciniae, Realgar, dried Alumen is fully mixed after, put into the alcoholic solution soaking and stirring of soaking Rhizoma Coptidis, after 3 days, filter out medicinal residues;
D, in the solution filtering out medicinal residues, add Moschus powder and stir evenly, sterilizing bottling is the external preparation for the treatment of herpes zoster.
5. the Chinese medicine for outer use using method for the treatment of herpes zoster disease according to claim 4, Chinese medicine preparation is embrocated affected part 3-10 times every day by patient.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105687310A (en) * | 2016-03-12 | 2016-06-22 | 海涛 | Mongolian medicine preparation for treating herpes zoster |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1442172A (en) * | 2003-04-02 | 2003-09-17 | 李淑凤 | External use medicine for treating blister sore |
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- 2015-11-30 CN CN201510843894.5A patent/CN105232667A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1442172A (en) * | 2003-04-02 | 2003-09-17 | 李淑凤 | External use medicine for treating blister sore |
Non-Patent Citations (1)
| Title |
|---|
| 邹铁建: "藤黄在皮肤病外治中的应用", 《中医外治杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105687310A (en) * | 2016-03-12 | 2016-06-22 | 海涛 | Mongolian medicine preparation for treating herpes zoster |
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Application publication date: 20160113 |