CN106309561A - Medicine for treating toothache and preparation method thereof - Google Patents
Medicine for treating toothache and preparation method thereof Download PDFInfo
- Publication number
- CN106309561A CN106309561A CN201610723971.8A CN201610723971A CN106309561A CN 106309561 A CN106309561 A CN 106309561A CN 201610723971 A CN201610723971 A CN 201610723971A CN 106309561 A CN106309561 A CN 106309561A
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- Prior art keywords
- radix
- medicine
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- gram
- mel
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/33—Cactaceae (Cactus family), e.g. pricklypear or Cereus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a medicine for treating a toothache and a preparation method thereof. The medicine is mainly prepared from mulberry roots, lotus leaves, spica prunellae, bitter gourds and cacti according to a certain weight ratio. The medicine has the functions of dispelling summer-heat, clearing away heat and toxic materials, promoting qi and activating blood, clearing away summer-heat and damp, and clearing the liver and resolving stasis, and is fast in effect taking, good in treatment effect and capable of preventing relapse when used for treating a toothache.
Description
Technical field
The present invention relates to a kind of medicine treating toothache and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Toothache refers to the pain that tooth causes because of a variety of causes, for one of symptom common in oral disease, it is seen that in
Dental caries, pulpitis, periapical periodontitis, tooth trauma, dentin hypersensitiveness, wedge shaped defect etc..The traditional Chinese medical science then think toothache with diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, stomach
Heated is contained, and hyperactivity of fire of suffering from a deficiency of the kidney is relevant.Owing to western medicine side effect is big, therefore the Chinese medicine of effectively treatment toothache is existed by people
Demand, up to now, does not the most find the relevant report about the present invention greatly.
Summary of the invention
The research of the present inventor's foundation theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found and effectively treat toothache
Medicine, thus complete the present invention.
It is an object of the invention to provide the Chinese medicine composition of a kind of effective treatment toothache.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention is to select Radix Mori, Folium Nelumbinis, Spica Prunellae, Fructus Momordicae charantiae, Radix et Caulis Opuntiae Dillenii, Mel to be combined preparation, by this
A little drug regimens make each efficacy of drugs produce synergism such that it is able to effectively treat toothache.Radix Mori is wherein selected to be because
Its nature and flavor warm up, nontoxic, control frightened, bones and muscles pain, hypertension, conjunctival congestion, thrush.Folium Nelumbinis is selected to be because its nature and flavor pained, flat, enter
The heart, liver, spleen channel, have clearing away summer-heat and eliminating dampness, sending up the lucid YANG, the function of hemostasis, controls diarrhea due to summer heat and dampness, dizziness, aqueous vapor edema, thunder-headache, tells
Blood, epistaxis, metrorrhagia, have blood in stool, puerperal blood faints.Spica Prunellae is selected to be because its nature and flavor toil, cold, enter liver, gallbladder meridian, have liver heat removing, dissipate
The function of knot, controls scrofula, goiter, acute mastitis, breast carcinoma, mesh pearl nyctalgia, and photophobia is shed tears, the vertigo, facial hemiparalysis, bones and muscles pain,
Pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia.Fructus Momordicae charantiae is selected to be because its nature and flavor bitter, cold, enter the heart, spleen, stomach three
Warp, has clearing away summer-heat to wash heat, improving eyesight, the function of removing toxic substances, controls calentura excessive thirst taking fluids profusely, heatstroke, dysentery, acute conjunctivitis pain, carbuncle erysipelas, dislikes
Skin ulcer.Radix et Caulis Opuntiae Dillenii is selected to be because its nature and flavor bitter, cold, enter the heart, lung, stomach three warp, have promoting flow of QI and blood, the function of heat-clearing and toxic substances removing, control the heart
Peratodynia, mass in the abdomen, dysentery, hemorrhoidal bleeding, cough, laryngalgia, lung abscess, acute mastitis, furuncle, burn, snakebite.Mel is selected to be because its property
Sweet in the mouth, flat, enter lung, spleen, large intestine channel, have invigorating middle warmer, moisturize, pain relieving, the function of removing toxic substances, control xeropulmonary cough, dryness of the intestine constipation, pain of gastric cavity
Bitterly, nasal sinusitis, aphtha, the burning hot wound of soup, solve Aconitum Carmichaeli.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, the consumption of each component under
All there is in stating weight range preferable curative effect:
Radix Mori 10-15 gram, 15-25 gram of Folium Nelumbinis, Spica Prunellae 15-25 gram, 15-25 gram of Fructus Momordicae charantiae, Radix et Caulis Opuntiae Dillenii 15-25 gram, Mel 5-15
Gram.
Preferable amount is
Radix Mori 12 grams, 20 grams of Folium Nelumbinis, Spica Prunellae 20 grams, 20 grams of Fructus Momordicae charantiae, Radix et Caulis Opuntiae Dillenii 20 grams, Mel 10 grams.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Mori: pick decontamination, dries；
2, Folium Nelumbinis: clean with water, cut off the base of a fruit and edge, shredding, dry；
3, Spica Prunellae: take crude drug, except discarding stalk, blade and impurity, sieve dedusting bits；
4, Fructus Momordicae charantiae: after autumn gather, section, dry；
5, Radix et Caulis Opuntiae Dillenii: extract fresh Radix et Caulis Opuntiae Dillenii according to quantity；
6, Mel: take pure Mel, temper with slow fire, filters skimming.
Two, preparation
1, the Radix Mori after concocting, Folium Nelumbinis, Spica Prunellae, Fructus Momordicae charantiae, Radix et Caulis Opuntiae Dillenii puts into decocting container, and add water 6 times amount, soaks 100
After minute, intense fire decocts boiling, then with slow fire boiling 20 minutes, filters to obtain first time decoction liquor, first time decoction liquor poured into
In container；
2, add water 4 times amount by the medicinal residues of filtration, and intense fire boils, then with slow fire boiling 20 minutes, filters to obtain second time decoction liquor；
3, twice decoction liquor is added the Mel mixing and stirring after concocting, be divided into 2 doses to take.
In prescription, Fructus Momordicae charantiae has clearing away summer-heat to wash heat, improving eyesight, and the function of removing toxic substances is monarch drug；Folium Nelumbinis clearing away summer-heat and eliminating dampness, sending up the lucid YANG, only
Blood；Radix et Caulis Opuntiae Dillenii has promoting flow of QI and blood, the function of heat-clearing and toxic substances removing, and the two is ministerial drug, and three taste medicines jointly play clearing away summer-heat and wash heat, heat clearing away solution
Poison, promoting flow of QI and blood, clearing away summer-heat and eliminating dampness, the effect of sending up the lucid YANG, treatment toothache effect is comprehensive, and washs heat with clearing away summer-heat, heat-clearing and toxic substances removing, OK
Gas is invigorated blood circulation, and clearing away summer-heat and eliminating dampness is that master can be effected a permanent cure, and Mel has invigorating middle warmer, moisturizes, pain relieving, and the function of removing toxic substances is adjuvant drug, and Spica Prunellae has liver heat removing,
The function of eliminating stagnation is for making medicine, and medicine all with remainder is to take stopgap measures.
Medicine of the present invention has clearing away summer-heat and washs heat, heat-clearing and toxic substances removing, promoting flow of QI and blood, clearing away summer-heat and eliminating dampness, the function of liver heat removing eliminating stagnation, is used for
Treatment toothache, short treating period, instant effect, non-relapse after healing.
The beneficial effect of of the present invention medicine is expanded on further below by way of test example, these test examples include this
The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention:
Taking rabbit 30, male and female dual-purpose, body weight 2.0 2.5kg, divide two groups, often group 15, one of which is overdose test
Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is that administration by gavage is given
Medicine, twice daily, serve on 7 days, observes every day and is administered reaction, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad
Toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept toothache out-patient's totally 23 example for medical treatment.
2, diagnostic criteria
Classical symptom is swelling and aching of gum, dysmasesis, thirsty halitosis, or time pain time only, meet caloric stimulation pain, buccal swelling
Deng.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each take 1 dose, take every day 3 times, within 7 days, be a course for the treatment of, take 1 continuously
The course for the treatment of.
4, efficacy assessment standard
Effective: toothache transference cure, recover normal, recovery from illness；
Taking a turn for the better: patient's swelling and aching of gum, dysmasesis, the phenomenon of thirsty halitosis alleviates, and toothache symptom is clearly better, and progressively recovers；
Invalid: not reach improvement standard person.
5, therapeutic outcome (see table)
In above-mentioned treatment, by Drug therapy patient with toothache 23 example of the present invention, effective 20 examples of result, obvious effective rate is 86.96%, good
Turning 2 examples, improvement rate is 8.7%, invalid 1 example, and total effective rate is 95.66%.
Claims (3)
1. the medicine treating toothache, it is characterised in that: it is made up of the crude drug in following weight range:
Radix Mori 10-15 gram, 15-25 gram of Folium Nelumbinis, Spica Prunellae 15-25 gram, 15-25 gram of Fructus Momordicae charantiae, Radix et Caulis Opuntiae Dillenii 15-25 gram, Mel 5-15
Gram.
Medicine the most according to claim 1, the consumption of the most each crude drug is:
Radix Mori 12 grams, 20 grams of Folium Nelumbinis, Spica Prunellae 20 grams, 20 grams of Fructus Momordicae charantiae, Radix et Caulis Opuntiae Dillenii 20 grams, Mel 10 grams.
The preparation method of medicine the most according to claim 1 or claim 2, it comprises the following steps:
(1) get the raw materials ready
1, Radix Mori: pick decontamination, dries；
2, Folium Nelumbinis: clean with water, cut off the base of a fruit and edge, shredding, dry；
3, Spica Prunellae: take crude drug, except discarding stalk, blade and impurity, sieve dedusting bits；
4, Fructus Momordicae charantiae: after autumn gather, section, dry；
5, Radix et Caulis Opuntiae Dillenii: extract fresh Radix et Caulis Opuntiae Dillenii according to quantity；
6, Mel: take pure Mel, temper with slow fire, filters skimming；
(2) prepare
(1) Radix Mori after concocting, Folium Nelumbinis, Spica Prunellae, Fructus Momordicae charantiae, Radix et Caulis Opuntiae Dillenii puts into decocting container, and add water 6 times amount, soaks 100
After minute, intense fire decocts boiling, then with slow fire boiling 20 minutes, filters to obtain first time decoction liquor, first time decoction liquor poured into
In container；
(2) add water 4 times amount by the medicinal residues of filtration, and intense fire boils, then with slow fire boiling 20 minutes, filters to obtain second time decoction liquor；
(3) twice decoction liquor is added the Mel mixing and stirring after concocting, be divided into 2 doses to take.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610723971.8A CN106309561A (en) | 2016-08-26 | 2016-08-26 | Medicine for treating toothache and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610723971.8A CN106309561A (en) | 2016-08-26 | 2016-08-26 | Medicine for treating toothache and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106309561A true CN106309561A (en) | 2017-01-11 |
Family
ID=57791353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610723971.8A Withdrawn CN106309561A (en) | 2016-08-26 | 2016-08-26 | Medicine for treating toothache and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106309561A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107233402A (en) * | 2017-05-22 | 2017-10-10 | 余新潮 | It is a kind of to treat compound oral syrup of toothache and preparation method thereof |
-
2016
- 2016-08-26 CN CN201610723971.8A patent/CN106309561A/en not_active Withdrawn
Non-Patent Citations (1)
| Title |
|---|
| 谢文英: "《名医珍藏祖传偏方》", 31 May 2014 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107233402A (en) * | 2017-05-22 | 2017-10-10 | 余新潮 | It is a kind of to treat compound oral syrup of toothache and preparation method thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170111 |