CN101940686B - Chinese medicinal composition for treating traumatic injury and preparation method thereof - Google Patents
Chinese medicinal composition for treating traumatic injury and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal composition for treating traumatic injury and a preparation method thereof. The Chinese medicinal composition for treating the traumatic injury comprises the following crude medicaments in part by weight: 2 to 8 parts of sappan wood, 2 to 8 parts of safflower, 1 to 6 parts of cutch, 5 to 15 parts of vinegar frankincense, 0.5 to 5 parts of clove, 5 to 35 parts of calcined pyrite, 3 to 15 parts of vinegar myrrh, 8 to 20 parts of drynaria rhizome, 0.1 to 2 parts of roasted nux vomica, 2 to 8 parts of dragon's blood, 2 to 8 parts of Himalayan teasel root and 0.1 to 1.5 parts of borneol. The Chinese medicinal composition can be prepared to be a clinically suitable oral preparation according to a conventional Chinese medicinal preparation method; the Chinese medicinal composition can be added with the following crude medicaments in part by weight: 2 to 6 parts of turmeric, 1 to 5 parts of siphonostegia chinensis and 0.05 to 1.5 parts of minium; and the Chinese medicinal composition can be prepared to be a preparation for external application according to the conventional Chinese medicinal preparation method. Clinical curative effect observation confirms that the Chinese medicinal composition contributes to the growth of callus and has exactly curative effects for various fractures.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, relate in particular to Chinese medicine composition of a kind of treatment traumatic injury (comprising delayed union of fracture or disunion) and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Fracture is that the integrity or the seriality of bone is interrupted or destroys.Its clinical manifestation is local swelling, deformity, tenderness, pseudoarticulation formation, afunction.Fracture is divided into TF and pathologisch Bruch.By the wound causer is TF, how by due to the big violence; And skeleton itself is because of certain disease, and is not normal etc. like tumor, inflammation, incretion balance, and robustness is affected, even under extremely slight external force, also can cause fracture, and this fracture is called pathologisch Bruch.
After fracture took place, the limb function at position, damage place was limited.Fracture therebetween will be through quite long process from occurring to healing, and the short then several months exceedes year at most.The condition of fracture itself is the Fundamentals that influence healing process, and Therapeutic Method and drug application are most important to union of fracture.
Though fracture at ordinary times or motion the time all can take place.The reason of fracture can be divided into traumatic and pathologic two big classes.TF is many to be caused by direct violence and indirect violence; The former like explosive injury, crush injury, get injured by a fall; The latter can produce colles' fracture, supracondylar fracture of the humerus, fracture of the surgical neek of the humerus etc. like the place hands on floor of falling; Pathological fracture is meant that skeleton itself is ill, under normal or slight wound situation, causes fracture.Whether TF can communicate with the external world according to fracture again, and is divided into closure and open two big classes.In addition, have or not from the shape of the degree of violence, fracture and fracture end and stagger or be shifted.Also can be divided into fully with incomplete fracture or horizontal stroke, tiltedly, pulverizing, spiral, inlay fracture, the fracture that is shifted or does not have displacement is arranged.
The existing Chinese medicine composition that is used to treat fracture all in various degree exist slow, the defective such as curative effect is definite inadequately that takes effect.
Summary of the invention
Technical problem to be solved by this invention is the deficiency that overcomes prior art, and a kind of Chinese medicine composition that significant curative effect is arranged (comprising fracture) for traumatic injury is provided.
Technical problem to be solved by this invention realizes through following technical scheme:
A kind of Chinese medicine composition of treating traumatic injury is made up of each crude drug of following weight portion: Lignum Sappan 2-8 part, Flos Carthami 2-8 part, catechu 1-6 part; Olibanum (processed with vinegar) 5-15 part, Flos Caryophylli 0.5-5 part, Pyritum (calcined) 5-35 part; Myrrha (processed with vinegar) 3-15 part, Rhizoma Drynariae 8-20 part, Semen Strychni (processed) 0.1-2 part; Sanguis Draxonis 2-8 part, Radix Dipsaci 2-8 part, Borneolum Syntheticum 0.1-1.5 part.
Preferably, the weight portion of each crude drug is: 4 parts of Lignum Sappans, 4 parts on Flos Carthami, 4 parts in catechu, 10 parts of Olibanum (processed with vinegar), 3 parts of Flos Caryophyllis, 28 parts of Pyritum (calcined)s, 10 parts of Myrrha (processed with vinegar), 16 parts of Rhizoma Drynariae, 1.8 parts of Semen Strychni (processed), 4 parts of Sanguis Draxonis, 4 parts of Radix Dipsacis, 0.85 part of Borneolum Syntheticum.
In order to reach better therapeutic effect, Chinese medicine composition of the present invention contains Lignum Sappan 2-8 part, Flos Carthami 2-8 part, catechu 1-6 part; Olibanum (processed with vinegar) 5-15 part, Flos Caryophylli 0.5-5 part, Pyritum (calcined) 5-35 part, Myrrha (processed with vinegar) 3-15 part; Rhizoma Drynariae 8-20 part, Semen Strychni (processed) 0.1-2 part, Sanguis Draxonis 2-8 part; Radix Dipsaci 2-8 part, Borneolum Syntheticum 0.1-1.5 part also can add Rhizoma Curcumae Longae 2-6 part, siphonostegia chinensis 1-5 part and Plumbum preparatium 0.05-1.5 part; Preferred, the weight portion of each crude drug is: Lignum Sappan 2-8 part, Flos Carthami 2-8 part, catechu 1-6 part; Olibanum (processed with vinegar) 5-15 part, Flos Caryophylli 0.5-5 part, Pyritum (calcined) 5-35 part, Myrrha (processed with vinegar) 3-15 part; Rhizoma Drynariae 8-20 part, Semen Strychni (processed) 0.1-2 part, Sanguis Draxonis 2-8 part, Radix Dipsaci 2-8 part; Borneolum Syntheticum 0.1-1.5 part, 3 parts in Rhizoma Curcumae Longae, 2 parts of siphonostegia chinensiss, 0.1 part of Plumbum preparatium.
The inventor passes through clinical research for many years; In conjunction with the dialectical principle that combines with differential diagnosis of diseases; Summary is given birth to marrow, channels sootheing and network vessel quickening, strengthened the muscle symplectic bone with eliminating stasis to stop pain, benefit bone is the pharmaceutical composition of the present invention of the main rule of treatment, helps growth of spur, has obtained ideal therapeutic effect for the treatment fracture.
Lignum Sappan: these article are the dry duramen of pulse family Semen Caesalpiniae platymiscium Lignum Sappan Caesalpinia sappan L..More than felling autumn, remove white sapwood, drying.Meridian distribution of property and flavor: sweet, one-tenth is flat.GUIXIN, liver, spleen channel.Function cures mainly: promoting the circulation of blood blood stasis dispelling, reducing swelling and alleviating pain.Be used for the amenorrhea dysmenorrhea, postpartum stagnation, breast ventral spine pain, wound swells and ache.
Flos Carthami: be the tubular flower of feverfew Flos Carthami Carthamus tinctorius L..Nature and flavor are warm in nature, acrid in the mouth.Function cures mainly: the latus rectum of invigorating blood circulation, eliminating stasis to stop pain.Be used for that amenorrhea, dysmenorrhea, lochia are not all right, lump in the abdomen mass in the abdomen, traumatic injury.
Catechu: be the peeling branch of pulse family albizzia plant catechu tree Acacia catechu (L.f.) Willd., dried dry soft extracts.Gather winter branch, do, remove crust, be chopped to bulk, decocte with water concentrates drying.Meridian distribution of property and flavor: bitter, puckery, be slightly cold.Return lung meridian.Function cures mainly: the removing dampness promoting tissue regeneration and ulcer healing.Be used for ulcer being unable to heal, eczema, aphtha is fallen and is pounced on the pain of injury, traumatic hemorrhage.
Olibanum: these article are olive subject plant Boswellia carterii Birdw Boswellia carterii Birdw. and the oleo-gum-resin that belongs to several plants together thereof.Effect: regulating QI, to invigorate blood circulation, pain relieving chases after poison.Antibiotic, the flatulence that restrains, dispels, promote that wound scabs, promotes cytoactive, sharp digestion, diuresis, calmness, benefit body, sharp uterus, controls wound.
Flos Caryophylli: be Myrtaceae syzygium species plant Flos Caryophylli (Eugenia caryophyllata Thunb. [E.aromatica Baill.; Syzygium aromatica (L) Merr.et Perry], with alabastrum and its fruit medicine.Effect: warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.Cure mainly: control singultus, vomiting, regurgitation, dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, ringworm.
Pyritum: be promoting blood circulation, removing blood stasis and relieving pain medicine commonly used.These article are sulfide-based mineral yellow iron mine family pyrite.Nature,taste and action: suffering, flat.Dissipating blood stasis, synthetism, pain relieving.Cure mainly usage: be used for treating swelling and pain by traumatic injury, the muscles and bones folding is hindered.Go into the diffusing clothes of ball more; External is ground into powder to transfer and is applied.
Myrrha: be the gum resin of olive subject plant myrrh or Alan's fort myrrh.Effect: the blood blood stasis removing that looses, subduing swelling and relieving pain.Meridian distribution of property and flavor: hardship, suffering, flat.Cure mainly: control traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.
Rhizoma Drynariae: meridian distribution of property and flavor: hardship, temperature.Return kidney, Liver Channel.Function cures mainly: the kidney invigorating bone strengthening continues and hinders pain relieving.Be used for lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, and the muscles and bones folding is hindered; The external treatment alopecia areata, vitiligo.
Semen Strychni: meridian distribution of property and flavor: hardship, cold, poisonous.Function cures mainly: removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.Be used for the rheumatoid arthritis stubborn paralysis and numbness, injury from falling down, ulcer sore pain; Poliomyelitis sequela, rheumatoid arthritis.Paralysis and numbness, myasthenia gravis etc.
Sanguis Draxonis: be the resin in babassu Sanguis Draxonis fruit and the trunk.Function cures mainly: control treating swelling and pain by traumatic injury, ecchymoma due to internal injury; Continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time.
Radix Dipsaci: these article are the dry root of Dipsacaceae plant Radix Dipsaci Dipsacus asperoides C.Y.Cheng et T.M.Ai (or Dipsacusa sper Wall).Meridian distribution of property and flavor: bitter, hot, tepor.Return liver, kidney channel.Function cures mainly: invigorating the liver and kidney, and bone and muscle strengthening, continuous folding is hindered, and ends metrorrhagia.Be used for soreness of the waist and knees, rheumatic arthralgia, metrorrhagia, vaginal bleeding during pregnancy, injury from falling down.
Rhizoma Curcumae Longae: be the dry root of zingiberaceous plant RADIX CURCUMAE Curcuma wenyujin Y.H.Chen et C.Ling.Nature and flavor with return through: hot, bitter, temperature.Return liver, spleen channel.Function with cure mainly: removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia.Be used for amenorrhea due to stagnation of blood, menalgia, the breast side of body twinges, rheumatic arthralgia, shoulder arm pain, injury from falling down.
Siphonostegia chinensis: be the dry herb of goatweed Herba Siphonostegiae.Siphonostegia chinensis (Herba Siphonostegiae) Herba siphonostegiae main product in northeast, ground such as Hebei, Henan, Shandong.Nature and flavor and effect: bitter in the mouth, warm in nature.There is removing blood stasis to stimulate the menstrual flow, the function of healing up sore and subduing swelling.Be used for the amenorrhea lump in the abdomen, postnatal blood stasis, traumatic injury, incised wound is hemorrhage, burn due to hot liquid or fire, carbuncle.
The used crude drug of the present invention all can be bought from common pharmacy and obtain, and its specification meets national medical standard.
Another technical problem to be solved by this invention provides a kind of method for preparing above-mentioned Chinese medicine composition.
Pharmaceutical composition of the present invention can be prepared into oral formulations or externally applied formulation according to the conventional method for preparing of extract oral or external preparation; Described oral formulations can be granule, tablet, powder, capsule, pill; Preferably, described pill watered pill preferably; Described externally applied formulation can be an emplastrum etc.
A kind of method for preparing above-mentioned Chinese medicine composition comprises:
(1) takes by weighing each crude drug by said weight portion;
(2) each crude drug is mixed, be ground into 80-200 purpose powder, promptly get.
The method of the above-mentioned Chinese medicine composition of another kind of preparation comprises:
(1) takes by weighing each crude drug by said weight portion;
(2) Lignum Sappan, Flos Carthami, Rhizoma Drynariae and Radix Dipsaci water are decocted, merging filtrate is condensed into thick paste or drying and crushing, and is subsequent use;
(3) with catechu, Olibanum (processed with vinegar), Flos Caryophylli, Pyritum (calcined), Myrrha (processed with vinegar), Semen Strychni (processed), Sanguis Draxonis and Borneolum Syntheticum mix, and are ground into powder and mix with above-mentioned thick paste or medicated powder, and drying is pulverized, and adds the adjuvant preparations shaping, promptly gets.
The method that another prepares above-mentioned Chinese medicine composition comprises:
(1) takes by weighing each crude drug by said weight portion;
(2) with Lignum Sappan, Flos Carthami, catechu; Olibanum (processed with vinegar), Flos Caryophylli, Myrrha (processed with vinegar); Rhizoma Drynariae, Semen Strychni (processed), Radix Dipsaci; Rhizoma Curcumae Longae and siphonostegia chinensis mix with vegetable oil soaks (consumption of vegetable oil only needs crude drug and do not get final product, and its consumption is more or a little less, can not cause substantial effect to enforcement of the present invention);
(3) there is the vegetable oil of material medicine to heat immersion, material medicine exploded after sallow remove medicinal residues, get medicine oil;
(4) the oily continuation heating of medicine is tempered, add the Plumbum preparatium in the medicine oil after tempering, be cooled to 60 ℃, add Borneolum Syntheticum, Pyritum (calcined) and Sanguis Draxonis, stir,, process externally applied formulation behind the one-tenth cream with the cold water cooling.
The usage of Chinese medicine composition of the present invention and consumption: with fracture site with clamping plate or plaster fixation after, spread on fracture with emplastrum of the present invention (each force on contain approximately crude drug 8-15 gram) heating back is outer, changed dressings once in every 1-3 days, treating 15 days continuously is a course of treatment.
The specific embodiment
Below further describe the present invention through embodiment, it should be understood that these embodiment only are used for the purpose of illustration, never limit protection scope of the present invention.
The preparation of embodiment 1 emplastrum
Take by weighing each raw material (unit: g): Lignum Sappan 400, Flos Carthami 400, catechu 400, Olibanum (processed with vinegar) 1000, Flos Caryophylli 300 by following weight; Pyritum (calcined) 2800, Myrrha (processed with vinegar) 1000, Rhizoma Drynariae 1600, Semen Strychni (processed) 180, Sanguis Draxonis 400; Radix Dipsaci 400, Borneolum Syntheticum 85, Rhizoma Curcumae Longae 300, siphonostegia chinensis 200, Plumbum preparatium 10;
With Lignum Sappan, Flos Carthami, catechu, Olibanum (processed with vinegar), Flos Caryophylli, Myrrha (processed with vinegar), Rhizoma Drynariae, Semen Strychni, Radix Dipsaci, Rhizoma Curcumae Longae and siphonostegia chinensis are soaked with vegetable oil 8000 grams; There is the vegetable oil of material medicine to heat immersion, material medicine exploded after sallow remove medicinal residues, get medicine oil; Medicine oil is continued heating temper in getting a little medicine oil droplet entry, oil droplet scatters and is as the criterion when assembling; Add the Plumbum preparatium in the medicine oil after tempering, behind the pilling and pasting, be cooled to 60 ℃, add the Borneolum Syntheticum of porphyrize, Pyritum (calcined) and Sanguis Draxonis stir, and after the cold water cooling, get an amount of the stand in the paper back, promptly get.
The preparation of embodiment 2 emplastrumes
Take by weighing each raw material (unit: g): Lignum Sappan 200, Flos Carthami 200, catechu 100, Olibanum (processed with vinegar) 500, Flos Caryophylli 50 by following weight; Pyritum (calcined) 500, Myrrha (processed with vinegar) 300, Rhizoma Drynariae 800, Semen Strychni (processed) 10, Sanguis Draxonis 200; Radix Dipsaci 200, Borneolum Syntheticum 10, Rhizoma Curcumae Longae 200, siphonostegia chinensis 100, Plumbum preparatium 5;
With Lignum Sappan, Flos Carthami, catechu, Olibanum (processed with vinegar), Flos Caryophylli, Myrrha (processed with vinegar), Rhizoma Drynariae, Semen Strychni, Radix Dipsaci, Rhizoma Curcumae Longae and siphonostegia chinensis are soaked with vegetable oil 8000 grams; There is the vegetable oil of material medicine to heat immersion, material medicine exploded after sallow remove medicinal residues, get medicine oil; Medicine oil is continued heating temper in getting a little medicine oil droplet entry, oil droplet scatters and is as the criterion when assembling; Add the Plumbum preparatium in the medicine oil after tempering, behind the pilling and pasting, be cooled to 60 ℃, add the Borneolum Syntheticum of porphyrize, Pyritum (calcined) and Sanguis Draxonis stir, and with the cold water cooling, get an amount of the stand in the paper back, promptly get.
The preparation of embodiment 3 emplastrumes
Take by weighing each raw material (unit: g): Lignum Sappan 800, Flos Carthami 800, catechu 600, Olibanum (processed with vinegar) 1500, Flos Caryophylli 500 by following weight; Pyritum (calcined) 3500, Myrrha (processed with vinegar) 1500, Rhizoma Drynariae 2000, Semen Strychni (processed) 200, Sanguis Draxonis 800; Radix Dipsaci 800, Borneolum Syntheticum 150, Rhizoma Curcumae Longae 600, siphonostegia chinensis 500, Plumbum preparatium 80;
With Lignum Sappan, Flos Carthami, catechu, Olibanum (processed with vinegar), Flos Caryophylli, Myrrha (processed with vinegar), Rhizoma Drynariae, Semen Strychni, Radix Dipsaci, Rhizoma Curcumae Longae and siphonostegia chinensis are soaked with vegetable oil 8000 grams; There is the vegetable oil of material medicine to heat immersion, material medicine exploded after sallow remove medicinal residues, get medicine oil; Medicine oil is continued heating temper in getting a little medicine oil droplet entry, oil droplet scatters and is as the criterion when assembling; Add the Plumbum preparatium in the medicine oil after tempering, behind the pilling and pasting, be cooled to 60 ℃, add the Borneolum Syntheticum of porphyrize, Pyritum (calcined) and Sanguis Draxonis stir, and with the cold water cooling, get an amount of the stand in the paper back, promptly get.
The preparation of embodiment 4 powders
Take by weighing each raw material (unit: g): Lignum Sappan 200, Flos Carthami 200, catechu 200, Olibanum (processed with vinegar) 500, Flos Caryophylli 150, Pyritum (calcined) 500, Myrrha (processed with vinegar) 500, Rhizoma Drynariae 500, Semen Strychni (processed) 85, Sanguis Draxonis 1000, Radix Dipsaci 200, Borneolum Syntheticum 50 by following weight; Above-mentioned each crude drug is mixed, be ground into 80-200 purpose powder, promptly get.
The preparation of embodiment 5 watered pill
Following weight is taken by weighing each raw material (unit: g): Lignum Sappan 400, Flos Carthami 400, catechu 400, Olibanum (processed with vinegar) 1000, Flos Caryophylli 300, Pyritum (calcined) 2800, Myrrha (processed with vinegar) 1000, Rhizoma Drynariae 1600, Semen Strychni (processed) 180, Sanguis Draxonis 400, Radix Dipsaci 400, Borneolum Syntheticum 85;
Lignum Sappan, Flos Carthami, Rhizoma Drynariae and Radix Dipsaci are added water 6-10 times of weight decoct 2-3 time, decocted 1.5-2 hour at every turn, decoction liquor filters, and merging filtrate is condensed into thick paste or drying and crushing, and is subsequent use;
With catechu, Olibanum (processed with vinegar), Flos Caryophylli, Pyritum (calcined), Myrrha (processed with vinegar), Semen Strychni (processed), Sanguis Draxonis and Borneolum Syntheticum mix, and are ground into 120-150 purpose powder and mix with above-mentioned thick paste or medicated powder, and drying is pulverized.Get the ethanol system soft material of 50%-80% medicated powder with 30%-60%, process the ball mould, reuse residue medicated powder is wetting agent with the ethanol of 10%-50%, with the big or small satisfactory pill of the general one-tenth of ball mould.
The clinical observation on the therapeutic effect test of Test Example 1 traditional Chinese medicine composition for treating fracture of the present invention
One, clinical data
Accept fracture patient 186 examples altogether for medical treatment, be divided into two test group at random; Wherein, test I organizes 93 examples, wherein, and arm open fracture 59 examples, arm closed fracture 34 examples.Test II organizes 93 examples, wherein, and arm open fracture 56 examples, arm closed fracture 37 examples.Two groups of patients do not have significant difference at aspects such as age, the patient's condition, the courses of disease.
Two, supply the reagent thing: the emplastrum that embodiment of the invention 1-4 is prepared.
Three, efficacy assessment standard (arm fracture):
Excellent: do not have into the displacement of angle and lateral deviation, forearm rotary moveable functional rehabilitation is normal.Very: be no more than 10 degree along bone physiology orphan degree angulation deformity, forearm rotary moveable functional rehabilitation is normal.Can: angulation deformity is about 15 degree, and antetheca rotary moveable function is unrestricted.Difference: angulation deformity is greater than 15 degree, and the activity of forearm spinfunction is obviously restricted.
Four, Therapeutic Method
Test group: adopt outpatient service or hospitalization.(for example adopt conventional doctor trained in Western medicine method treatment earlier for fracture patient; Suitable steel plate is selected in debridement for use after the reduction of the fracture, screw or intramedullary needle internal fixation; The plaster slab external fixation); To supply reagent thing plaster (each is forced on and contains crude drug 8-15 gram approximately) heating to spread on fracture outside the back again, change dressings once in every 2-3 days, treating 15 days continuously is a course of treatment.Wherein, test I group adopts the prepared emplastrum of embodiment 1-3 to treat; Test II group adopts embodiment 4 prepared powder (oral: each 2-3g crude drug, every day 3 times) or embodiment 5 prepared watered pill to treat.
Five, therapeutic outcome
Test I group: 21 days the earliest clinical healing time, 108 days at the latest, average 30.5 days.Wherein, excellent: 81 examples (87.09%), good: 9 examples (9.6%), can: 2 examples (2.18%), poor: 1 example (1.09%), acceptance rate reaches 96.69%.
Test II group: 27 days the earliest clinical healing time, 128 days at the latest, average 35.5 days.Wherein, excellent: 72 examples (77.4%), good: 10 examples (10.7%), can: 7 examples (7.5%), differ from 4 examples (4.3%), acceptance rate is 88.1%.
Clinical observation on the therapeutic effect is the result show; Chinese medicine composition of the present invention all has definite curative effect for all kinds of fracture; Wherein, the clinical efficacy of the emplastrum of embodiment 1-3 treatment fracture significantly is superior to the therapeutic effect of watered pill of powder or the embodiment 5 of embodiment 4, and the two has significant difference.
Claims (10)
1. a Chinese medicine composition of treating traumatic injury is characterized in that, comprises that each crude drug of following weight portion is processed: Lignum Sappan 2-8 part, Flos Carthami 2-8 part; Catechu 1-6 part, Olibanum (processed with vinegar) 5-15 part, Flos Caryophylli 0.5-5 part, Pyritum (calcined) 5-35 part; Myrrha (processed with vinegar) 3-15 part, Rhizoma Drynariae 8-20 part, Semen Strychni (processed) 0.1-2 part; Sanguis Draxonis 2-8 part, Radix Dipsaci 2-8 part, Borneolum Syntheticum 0.1-1.5 part.
2. according to the Chinese medicine composition of claim 1, it is characterized in that the weight portion of each crude drug is: 4 parts of Lignum Sappans, 4 parts on Flos Carthami, 4 parts in catechu; 10 parts of Olibanum (processed with vinegar), 3 parts of Flos Caryophyllis, 28 parts of Pyritum (calcined)s, 10 parts of Myrrha (processed with vinegar), 16 parts of Rhizoma Drynariae; 1.8 parts of Semen Strychni (processed), 4 parts of Sanguis Draxonis, 4 parts of Radix Dipsacis, 0.85 part of Borneolum Syntheticum.
3. according to claim 1 or 2 described Chinese medicine compositions, it is characterized in that: be prepared into oral formulations according to Chinese medicine conventional formulation method; Described oral formulations comprises granule, tablet, powder, capsule or pill.
4. according to the Chinese medicine composition of claim 1, it is characterized in that, also contain each crude drug of following weight portion: Rhizoma Curcumae Longae 2-6 part, siphonostegia chinensis 1-5 part and Plumbum preparatium 0.05-0.8 part.
5. according to the described Chinese medicine composition of claim 4, it is characterized in that, be prepared into outer application preparation according to Chinese medicine conventional formulation method.
6. according to the described Chinese medicine composition of claim 5, it is characterized in that described outer application preparation is obedient unguentum.
7. method for preparing claim 1 or 2 described Chinese medicine compositions comprises:
(1) takes by weighing each crude drug by said weight portion;
(2) Lignum Sappan, Flos Carthami, Rhizoma Drynariae and Radix Dipsaci water are decocted, merging filtrate is condensed into thick paste, and is subsequent use;
(3) with catechu, Olibanum (processed with vinegar), Flos Caryophylli, Pyritum (calcined), Myrrha (processed with vinegar), Semen Strychni (processed), Sanguis Draxonis and Borneolum Syntheticum mix, and are ground into powder and mix with above-mentioned thick paste, and drying is pulverized, and adds the adjuvant preparations shaping, promptly gets.
8. method for preparing claim 4 or 5 described Chinese medicine compositions comprises:
(1) takes by weighing each crude drug by said weight portion;
(2) with Lignum Sappan, Flos Carthami, catechu, Olibanum (processed with vinegar), Flos Caryophylli, Myrrha (processed with vinegar), Rhizoma Drynariae, Semen Strychni (processed), Radix Dipsaci, Rhizoma Curcumae Longae and siphonostegia chinensis mix with vegetable oil soaks;
(3) there is the vegetable oil of material medicine to heat immersion, material medicine exploded after sallow remove medicinal residues, get medicine oil;
(4) the oily continuation heating of medicine is tempered, add the Plumbum preparatium in the medicine oil after tempering, be cooled to 60 ℃, add Borneolum Syntheticum, Pyritum (calcined) and Sanguis Draxonis, stir,, process externally applied formulation behind the one-tenth cream with the cold water cooling.
9. claim 1 or 2 described Chinese medicine compositions are treated the purposes in the traumatic injury medicine in preparation; Wherein, described traumatic injury comprises fracture.
10. claim 3 or 4 described Chinese medicine compositions are treated the purposes in the traumatic injury medicine in preparation; Wherein, described traumatic injury comprises fracture.
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| CN105213683A (en) * | 2015-09-28 | 2016-01-06 | 三穗县中医医院 | A kind of medicine and preparation method thereof for the treatment of traumatic injury, soft tissue injury |
| CN105106521A (en) * | 2015-10-16 | 2015-12-02 | 韩守江 | Analgesic for traumatic injuries |
| CN105168315A (en) * | 2015-10-19 | 2015-12-23 | 郑州中医骨伤病医院 | Zijin blood-dissipating pill for treating soft tissue contusion and early fracture |
| CN106110189A (en) * | 2016-07-19 | 2016-11-16 | 周继英 | A kind of Chinese medicine composition treating traumatic injury |
| CN107213423A (en) * | 2017-06-07 | 2017-09-29 | 李建运 | A kind of bone-setting ointment and preparation method thereof |
| CN111568986B (en) * | 2020-05-18 | 2021-12-14 | 葛亚金 | Chinese medicinal oral prescription for setting fracture, external ointment and preparation method thereof |
| CN111603546A (en) * | 2020-06-23 | 2020-09-01 | 河南省正骨研究院 | Ointment for treating acute injury and preparation method thereof |
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| CN101422552A (en) * | 2007-10-29 | 2009-05-06 | 郭继焕 | Traditional Chinese medicine black plaster capable of activating blood circulation to dissipate blood stasis, knitting bone and alleviating pain and preparation technique thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101422552A (en) * | 2007-10-29 | 2009-05-06 | 郭继焕 | Traditional Chinese medicine black plaster capable of activating blood circulation to dissipate blood stasis, knitting bone and alleviating pain and preparation technique thereof |
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