CN105456509A - Plaster for treating spondylodynia and preparation method thereof - Google Patents

Plaster for treating spondylodynia and preparation method thereof Download PDF

Info

Publication number
CN105456509A
CN105456509A CN201511014096.8A CN201511014096A CN105456509A CN 105456509 A CN105456509 A CN 105456509A CN 201511014096 A CN201511014096 A CN 201511014096A CN 105456509 A CN105456509 A CN 105456509A
Authority
CN
China
Prior art keywords
parts
radix
radix aconiti
plaster
colophonium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201511014096.8A
Other languages
Chinese (zh)
Inventor
苗宗礼
苗康
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201511014096.8A priority Critical patent/CN105456509A/en
Publication of CN105456509A publication Critical patent/CN105456509A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125Camphor; Nuclear substituted derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/646Arachnids, e.g. spiders, scorpions, ticks or mites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/648Myriapods, e.g. centipedes or millipedes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/65Amphibians, e.g. toads, frogs, salamanders or newts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254Acanthopanax or Eleutherococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Insects & Arthropods (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides a plaster for treating spondylodynia and a preparation method thereof, and belongs to the technical field of traditional Chinese medicinal plasters. The plaster is prepared from the following raw materials in parts by weight: 15-20 parts of semen strychni, 5-8 parts of flos daturae, 7-10 parts of radix aconiti agrestis, 7-10 parts of radix aconiti, 7-10 parts of flos carthami, 5-8 parts of cinnamon, 7-10 parts of eucommia ulmoides, 7-10 parts of radix aconiti carmichaeli, 7-10 parts of achyranthes bidentata, 7-10 parts of saposhnicovia divaricata, 7-10 parts of ephedra, 7-10 parts of angelica sinensis, 7-10 parts of cortex acanthopanacis, 5-8 parts of asarum, 7-10 parts of pangolin scales, 7-10 parts of centipedes, 5-8 parts of garden balsam, 5-8 parts of phryma leptostachya, 5-8 parts of cassia twig, 20-60 parts of dried toads, 7-10 parts of borneol, 7-10 parts of scorpion, 30-60 parts of camphor, 200-300 parts of rosin and 30-100 parts of sesame oil. The plaster can be used for effectively treating spondylodynia and complications caused by spondylodynia so as to relieve pains of patients.

Description

A kind of plaster for the treatment of spondylopathy and preparation method thereof
Technical field
The present invention relates to a kind of plaster for the treatment of spondylopathy and preparation method thereof, belong to Chinese medicine plaster technical field.
Background technology
Spondylopathy is exactly sclerotin, intervertebral disc, ligament, the muscle generation pathological changes of vertebra, and then compressing, traction stimulate spinal cord, spinal nerves, blood vessel, vegetative nerve thus occur complicated and diversified symptom.Commonly encountered diseases kind is cervical spondylosis, lumbar spondylosis.Cardinal symptom: can not uprightly, headache, dizzy, blurred vision, hypomnesis, neck shoulder ache, inappetence, regurgitation, vomiting, weakness of the lower extremities, severe patient may cause paralysis.
The mode of current treatment spondylopathy is Drug therapy and operative treatment.Due to the affected part of spondylopathy and the central nervous system of people closely bound up, the risk of operative treatment is comparatively large, adopts Drug therapy at present more.In Drug therapy, plaster is the dosage form comparatively commonly used, and can to go directly affected part through skin in therapeutic process, docile more for convenience.But current existing plaster exists following problem: the first, the plaster of existing treatment vertebra disease often cannot effect a radical cure, and can only play the effect temporarily delaying ongoing disease, easy Relapse rate after drug withdrawal; Second, the neuropathic pain treatment effect that the plaster of existing treatment vertebra disease causes for spondylopathy is undesirable, and articuli intervertebrales damage is eased over the course for the treatment of, but pain, feeling of numbness still sustainable existence, bring larger misery to patient, reduce the quality of life of patient.Three, the existing plaster obvious therapeutic effect of complication thing that spondylopathy is caused.
Summary of the invention
The technical problem to be solved in the present invention is: overcome the deficiencies in the prior art, provides a kind of plaster for the treatment of spondylopathy and preparation method thereof, and the plaster of this treatment spondylopathy effectively can treat spondylopathy, and the complication that spondylopathy causes, and reduction of patient is painful.
The technical solution adopted for the present invention to solve the technical problems is: the plaster of this treatment spondylopathy, it is characterized in that, be made up of the raw material of following weight portion: Semen Strychni 15 ~ 20 parts, Flos Daturae 5 ~ 8 parts, Radix Aconiti Kusnezoffii 7 ~ 10 parts, Radix Aconiti 7 ~ 10 parts, 7 ~ 10 parts, Flos Carthami, Cortex Cinnamomi 5 ~ 8 parts, the Cortex Eucommiae 7 ~ 10 parts, Radix Aconiti Lateralis Preparata 7 ~ 10 parts, Radix Achyranthis Bidentatae 7 ~ 10 parts, Radix Saposhnikoviae 7 ~ 10 parts, 7 ~ 10 parts, Herba Ephedrae, Radix Angelicae Sinensis 7 ~ 10 parts, Cortex Acanthopancis 7 ~ 10 parts, Herba Asari 5 ~ 8 parts, Squama Manis scute 7 ~ 10 parts, Scolopendra 7 ~ 10 parts, Semen Impatientis 5 ~ 8 parts, Herba speranskiae tuberculatae 5 ~ 8 parts, Ramulus Cinnamomi 5 ~ 8 parts, Bufo siccus 20 ~ 60 parts, Scorpio 7 ~ 10 parts, Borneolum Syntheticum 7 ~ 10 parts, Camphora 30 ~ 60 parts, Colophonium 200 ~ 300 parts, Oleum sesami 30 ~ 150 parts.
The plaster of this treatment spondylopathy, it is characterized in that, be made up of the raw material of following weight portion: Semen Strychni 18 ~ 20 parts, Flos Daturae 6 ~ 7 parts, Radix Aconiti Kusnezoffii 7 ~ 9 parts, Radix Aconiti 7 ~ 9 parts, 7 ~ 9 parts, Flos Carthami, Cortex Cinnamomi 5 ~ 6 parts, the Cortex Eucommiae 7 ~ 9 parts, Radix Aconiti Lateralis Preparata 7 ~ 9 parts, Radix Achyranthis Bidentatae 7 ~ 9 parts, Radix Saposhnikoviae 7 ~ 9 parts, 7 ~ 9 parts, Herba Ephedrae, Radix Angelicae Sinensis 7 ~ 9 parts, Cortex Acanthopancis 7 ~ 9 parts, Herba Asari 6 ~ 7 parts, Squama Manis scute 7 ~ 9 parts, Scolopendra 7 ~ 9 parts, Semen Impatientis 6 ~ 7 parts, Herba speranskiae tuberculatae 6 ~ 7 parts, Ramulus Cinnamomi 6 ~ 7 parts, Bufo siccus 50 ~ 60 parts, Scorpio 7 ~ 9 parts, Borneolum Syntheticum 7 ~ 9 parts, Camphora 45 ~ 50 parts, Colophonium 200 ~ 250 parts, Oleum sesami 50 ~ 85 parts.
The plaster of this treatment spondylopathy, it is characterized in that, be made up of the raw material of following weight portion: Semen Strychni 20 parts, Flos Daturae 6 parts, Radix Aconiti Kusnezoffii 9 parts, Radix Aconiti 9 parts, 9 parts, Flos Carthami, Cortex Cinnamomi 5 parts, the Cortex Eucommiae 9 parts, Radix Aconiti Lateralis Preparata 9 parts, Radix Achyranthis Bidentatae 9 parts, Radix Saposhnikoviae 9 parts, 9 parts, Herba Ephedrae, Radix Angelicae Sinensis 9 parts, Cortex Acanthopancis 9 parts, Herba Asari 7 parts, Squama Manis scute 9 parts, Scolopendra 9 parts, Semen Impatientis 7 parts, Herba speranskiae tuberculatae 7 parts, Ramulus Cinnamomi 7 parts, Bufo siccus 55 parts, Scorpio 9 parts, Borneolum Syntheticum 9 parts, Camphora 50 parts, Colophonium 200 parts, Oleum sesami 60 ~ 80 parts.
The manufacture method of the plaster of this treatment spondylopathy, is characterized in that, adopts following steps:
1) method for making of Colophonium substrate: the Colophonium taken by weight ratio, Oleum sesami are added in temperature control pot, kettle temperature is controlled at 95 ~ 110 DEG C, until melted completely by Colophonium, namely obtain Colophonium substrate after stirring;
2) Semen Strychni, Flos Daturae, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Carthami, Cortex Cinnamomi, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Radix Achyranthis Bidentatae, Radix Saposhnikoviae, Herba Ephedrae, Radix Angelicae Sinensis, Cortex Acanthopancis, Herba Asari, Squama Manis scute, Scolopendra, Semen Impatientis, Herba speranskiae tuberculatae, Ramulus Cinnamomi, Bufo siccus and Scorpio is claimed by weight ratio, it is dropped in Chinese medicine grinder respectively, 400 ~ 500 mesh sieves are crossed after pulverizing, mix homogeneously, obtains medicated powder; Borneolum Syntheticum, Camphora were pulverized respectively 80 ~ 150 orders and obtained Borneolum Syntheticum powder and camphor powder;
3) by step 2) medicated powder that obtains adds in the Colophonium substrate that step 1) obtains, keeps Colophonium substrate temperature 95 ~ 110 DEG C, after stirring, obtain paste in adition process;
4) paste is cooled to 50 ~ 60 DEG C, in paste, adds step 2) gained Borneolum Syntheticum powder and camphor powder, be uniformly mixed and obtain plaster mastic;
5) by plaster mastic 30 ~ 60 grams, be pressed into the cake of thickness 2 ~ 5mm, cake be put on non-woven fabrics, obtain final product.
Semen Strychni, bitter, temperature; Return liver, spleen channel.Function cures mainly: removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.For rheumatoid arthritis stubborn, paralysis and numbness, injury from falling down, ulcer sore pain; Poliomyelitis sequela, rheumatoid arthritis.
Flos Daturae, pungent, temperature.Return lung, Liver Channel.Antiasthmatic-antitussive, analgesia, spasmolytic.For asthma and cough, coldness and pain in the epigastrium, rheumatic arthralgia, children's's intermittent infantile convulsion; Surgical anesthesia.
Radix Aconiti Kusnezoffii, property is pungent, bitter, heat.GUIXIN, liver,kidney,spleen warp.Function is expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Radix Aconiti, property is pungent, bitter, heat.GUIXIN, liver,kidney,spleen warp.Function cures mainly: expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Flos Carthami, nature and flavor: pungent, temperature.Gui Jing: GUIXIN, Liver Channel.Function cures mainly: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Cortex Cinnamomi, hot in nature, acrid in the mouth, sweet.Return kidney, spleen, the heart, Liver Channel function to be dispersing cold for relieving pain, mend promoting blood circulation to restore menstrual flow.Fire is supporing yang, let the fire back to its origin.For trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, amenorrhea, dysmenorrhea, warming the meridian and promoting blood circulation.
The Cortex Eucommiae, nature and flavor are sweet micro-pungent, temperature.Return liver, kidney channel.Function is invigorating the liver and kidney, and bone and muscle strengthening is antiabortive.Cure mainly: spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, vaginal bleeding during pregnancy for falling, hypertension.
Radix Aconiti Lateralis Preparata, pungent, sweet, hot greatly.GUIXIN, kidney, spleen channel.Recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.For YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
Radix Achyranthis Bidentatae, this product is the dry root of amaranthaceous plant Radix Cyathulae.Bitter, sour, flat.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.For soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, dizziness due to hyperactivity of liver-YANG.
Radix Saposhnikoviae, property is pungent, sweet, tepor.Return lung, bladder, liver, spleen channel.Function is expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion.For feeling rheumatism or rheumatic arthralgia.
Herba Ephedrae, pungent, micro-hardship, temperature, returns lung, urinary bladder channel; Effect: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.Cure mainly: anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema; Be used for table disease to separate, asthma and cough.Herba ephedrae inclined profit warm in nature, pungent loose perspiration relaxes, and enhances the merit of nourishing the lung to arrest cough, wins with depressed lung-energy dispersing cough-relieving power.Separating for showing disease, asthma and cough, suppressing irritated tramsmitter release.
Radix Angelicae Sinensis, property sweet, acrid, warm.Return liver, the heart, spleen channel.Function is invigorated blood circulation for enriching blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For rheumatic arthralgia, injury from falling down, blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, dryness of the intestine constipation.
Cortex Acanthopancis, nature and flavor: pungent, bitter, temperature.Gui Jing: return liver, kidney channel.Function cures mainly: wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening.For rheumatic arthralgia, muscles and bones flaccidity is soft, children's's walking retardation in children, and body void is weak, edema, beriberi.
Herba Asari, nature and flavor: pungent, temperature.Return lung meridian, kidney channel, heart channel, Liver Channel, gallbladder meridian, spleen channel; Effect: induce sweat cold expelling; Wind-expelling pain-stopping; Warming the lung to resolve fluid-retention, sensible; Cure mainly: exterior syndrome due to wind-cold, headache, toothache, rheumatic arthralgia, phlegm retention cough with asthma, nasal obstruction, nasal sinusitis, aphtha, separately has antiinflammatory, immunosuppressant, local anesthesia effect.
Squama Manis scute, salty in the mouth; Cold nature, returns liver; Stomach warp, cures mainly blood circulation promoting and dispersing pathogen accumulation; To stimulate the menstrual flow stimulating milk secretion; Eliminating carbuncle is burst hard.Main blood stasis amenorrhea; Lump in the abdomen; Rheumatic arthralgia; Agalactia; Carbuncle; Scrofula.Squama Manis can reduce clotting time, reduce blood viscosity, can clear up lipid metabolism refuse in blood.
Scolopendra, this product is that the dry body nature and flavor of Scolopendridae animal Scolopendpa Subspinipes Mutilans L. KOCH are pungent, temperature; Return Liver Channel.Cure mainly endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.
Semen Impatientis, this product is the dry mature seed of Balsaminaceae plant Flos Impatientis.Micro-hardship, pungent, temperature; Return lung, Liver Channel.Clots absorbing sending down the abnormal ascending QI; Hard masses softening and resolving.Main warp closes; Dysmenorrhea; Dystocia; Retention of placenta in puerperal, dysphagic; Mass in the abdomen; Bone is choked; Dirty tooth; Sore swollen toxin.Semen Impatientis also has antibacterial action: all have inhibitory action in various degree to staphylococcus aureus, Hemolytic streptococcus, bacillus pyocyaneus, shigella flexneri, sonne bacillus, Bacillus typhi.
Herba speranskiae tuberculatae is euphorbia plant speranskia tuberculata, nature and flavor: bitter, cold.Function cures mainly: heat-clearing and toxic substances removing, removing heat from blood suppressing the hyperactive liver.For upper respiratory tract infection, tonsillitis, pharyngitis, bronchitis, pneumonia, lung abscess, gastroenteritis, hepatitis, appendicitis, mastitis, acute conjunctivitis, hypertension; Traumatic injury is controlled in external, traumatic hemorrhage, carbuncle furuncle infections, burn and scald, venom.
Ramulus Cinnamomi, nature and flavor: acrid, sweet, warm.Gui Jing: GUIXIN, lung, urinary bladder channel.Function cures mainly: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus.
Bufo siccus, Bufonidae animal Bufo siccus or Bufo melanostictus, the drying of removing internal organs is all.Pungent, cool.Enter the heart, liver, spleen, lung four warp.Broken crux, row water wets, removing toxic substances, parasite killing, analgesic therapy.Control furuncle, carbuncle on the back, carbuncle of yin nature scrofula, malignant boil, the lump in the abdomen hypochondriac lump, tympanites, edema, infantile malnutrition, chronic tracheitis.
Borneolum Syntheticum, this product is the crystallization obtained from the resin and volatile oil of Dipterocarpaceae trees, pungent, bitter, is slightly cold.GUIXIN, spleen, lung meridian.To have one's ideas straightened out refreshment, clearing away heat to alleviate pain.Faint for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, and conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
Scorpio, this product is the dry body of Buthidae animal Scorpio, pungent, flat; Poisonous.Return Liver Channel.Cure mainly and dispel the wind, relieving convulsion, dredging collateral, removing toxic substances, endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
Camphora, pungent, temperature.Sensible ward off dirty, warming middle-JIAO to relieve pain, dampness removing parasite killing.Vomit and diarrhoea for cold-damp, stomach abdomen pain; Scabies is controlled in external, tinea, dental caries are had a pain.
Colophonium, bitter sweet, temperature; Enter spleen, lung two warp, function cures mainly: dispel the wind, dampness, and evacuation of pus is drawn out pus by applying a plaster to the affected part, granulation promoting, pain relieving.Control carbuncle, furunculosis, hemorrhoid complicated by anal fistula, malignant boil.Scabies, bald in vain, incised wound, sprains, rheumatic arthralgia, leprosy pruritus.
Oleum sesami, sweet, cool.Enter meridian of Hand-YANG MING.Function cures mainly: moistening dryness for relaxing bowels, removing toxic substances, granulation promoting.Control dryness of the intestine constipation, ascarid, abdominal pain due to retention of food, skin ulcer swells, ulcer, scabies, chapped skin.
Applicant finds under study for action: the numbness of spinal lesions, pain cause the symptom of maximum misery, not only affects the orthobiosis of patient, also affect the mood of patient.And the complication that spondylopathy causes often is difficult to radical cure, bring long-standing problem to patient.Over the course for the treatment of, the joint injury that often there is spinal lesions is treated effective or cures, but the pain of patient, feeling of numbness and spondylopathy complication thereof take effect slowly or be difficult to the problem of radical cure.Its subject matter is: responding well to treatment of the disease of the joint of affected part, ligament and muscle is fast, but nerve injury treatment around affected part slowly and be difficult to cure, and existing plaster is of short duration alleviating pain.The symptom of spondylopathy and complication thereof is many to stimulate due to neural blood vessel and damage causes, and wherein complication is many stimulates spinal cord, spinal nerves, blood vessel, vegetative nerve thus the disease of the health multiple organ occurred due to compressing, traction.
Applicant devises Flos Daturae, Radix Aconiti Kusnezoffii, Radix Aconiti, Herba Asari and Bufo siccus coupling in formula, by the pain of the mechanism rapid recovery joint affected part of narcotic analgesic, reduces the misery of patient.Semen Strychni, Flos Carthami, Cortex Cinnamomi, Radix Achyranthis Bidentatae, Radix Saposhnikoviae, Semen Impatientis, Scolopendra and Scorpio coupling can warming the meridian and promoting blood circulation, relieving convulsion pain relieving, accelerate the blood circulation of joint affected part, repair impaired neurocyte gradually, to treat spondylopathy complication.The Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Squama Manis scute, Cortex Acanthopancis, Herba Ephedrae, Herba speranskiae tuberculatae, Bufo siccus can strengthening the tendons and bones, antiinflammatory toxin expelling, dispersing swelling and dissipating binds, discharges the toxin of joint affected part deposition, recovers the normal function of articular cartilage, ligament, muscular tissue.Squama Manis scute, Scolopendra, Bufo siccus and Scorpio, can help the toxin of discharging the alluvial of shutdown affected part.
In formula: Semen Strychni, Radix Aconiti Kusnezoffii, Radix Aconiti, Radix Aconiti Lateralis Preparata are crude drug.Crude drug is namely without the vegetable drug of any process of preparing Chinese medicine.Semen Strychni, Radix Aconiti Kusnezoffii, Radix Aconiti and Radix Aconiti Lateralis Preparata stir with 95 ~ 110 DEG C of Colophonium substrate in the step 3) of rear continuous preparation, Colophonium in Colophonium substrate and Oleum sesami coupling can play collaborative effect of drawing out pus by applying a plaster to the affected part, and obviously can reduce the untoward reaction that brings of toxicity of Semen Strychni, Radix Aconiti Kusnezoffii, Radix Aconiti, Radix Aconiti Lateralis Preparata under the effect of high temperature and Colophonium substrate.The Rhizoma Pinelliae of 1 ~ 10 part also can be added in formula of the present invention.Bufo siccus used in formula of the present invention is that the drying of removing internal organs is all, is preferably Bufo siccus.Study through applicant and find that in plaster of the present invention, Bufo siccus not easily replaces with toad clothing or Venenum Bufonis, it is undesirable that Bufo siccus equivalent replaces with toad clothing effect when treating the disease of articular cartilage damage, and Venenum Bufonis therapeutic effect is inferior to toad clothing.And after applicant finds that Bufo siccus equivalent replaces with Venenum Bufonis, effective percentage without significant difference, but in some cases patient occur having palpitation, rapid breathing, insomnia untoward reaction, be changed to the plaster of the present invention of equal consumption proportion after stopping using, be then difficult ill symptoms.Applicant considers that spondylopathy is mainly in middle-older patient, and its internal organs are comparatively weak, and therefore can only use Bufo siccus in formula of the present invention, its therapeutic effect is good, and safety is higher.
Applicant finds under study for action: evident in efficacy in the short time after existing spondylopathy plaster treatment, but there is the problem of easily recurrence.Confirm that this problem causes because the fibrous ring of vertebra place periarticular ligament (as supraspinal ligament, interspinal ligaments, ligamenta flava, anterior longitudinal ligament), articuli intervertebrales follows the string after deliberation, existing plaster can only shor time treatment but still there is the risk of recurrence.In formula, applicant designs Semen Strychni 15 ~ 20 parts, Flos Daturae 5 ~ 8 parts, Radix Aconiti Kusnezoffii 7 ~ 10 parts, Radix Aconiti 7 ~ 10 parts, 7 ~ 10 parts, Flos Carthami, Cortex Cinnamomi 5 ~ 8 parts, the Cortex Eucommiae 7 ~ 10 parts, Radix Aconiti Lateralis Preparata 7 ~ 10 parts, Radix Achyranthis Bidentatae 7 ~ 10 parts, Radix Saposhnikoviae 7 ~ 10 parts, 7 ~ 10 parts, Herba Ephedrae, Radix Angelicae Sinensis 7 ~ 10 parts, Cortex Acanthopancis 7 ~ 10 parts, Herba Asari 5 ~ 8 parts, Squama Manis scute 7 ~ 10 parts, Scolopendra 7 ~ 10 parts, Semen Impatientis 5 ~ 8 parts, Herba speranskiae tuberculatae 5 ~ 8 parts, Ramulus Cinnamomi 5 ~ 8 parts, Bufo siccus 20 ~ 60 parts, Scorpio 7 ~ 10 parts, the formula of Borneolum Syntheticum 7 ~ 10 parts and Camphora 30 ~ 60 parts can be widely used in treatment joint type disease, comprise vertebral articulations and knee joint, elbow joint, carpal joint, finger-joint.But arbitrarily collocation possesses extensive curative effect in this ratio range, total effective rate is more than 85%, wherein treat slight joint injury cure rate and can reach more than 95%, but specific aim is not possessed for the treatment of the joint disease of severe and moderate, and cure rate is relatively on the low side.Applicant finally determines after deliberation: Semen Strychni 18 ~ 20 parts, Flos Daturae 6 ~ 7 parts, Radix Aconiti Kusnezoffii 7 ~ 9 parts, Radix Aconiti 7 ~ 9 parts, 7 ~ 9 parts, Flos Carthami, Cortex Cinnamomi 5 ~ 6 parts, the Cortex Eucommiae 7 ~ 9 parts, Radix Aconiti Lateralis Preparata 7 ~ 9 parts, Radix Achyranthis Bidentatae 7 ~ 9 parts, Radix Saposhnikoviae 7 ~ 9 parts, 7 ~ 9 parts, Herba Ephedrae, Radix Angelicae Sinensis 7 ~ 9 parts, Cortex Acanthopancis 7 ~ 9 parts, Herba Asari 6 ~ 7 parts, Squama Manis scute 7 ~ 9 parts, Scolopendra 7 ~ 9 parts, Semen Impatientis 6 ~ 7 parts, Herba speranskiae tuberculatae 6 ~ 7 parts, Ramulus Cinnamomi 6 ~ 7 parts, Bufo siccus 50 ~ 60 parts, Scorpio 7 ~ 9 parts, Borneolum Syntheticum 7 ~ 9 parts, the consumption proportion that Camphora is 45 ~ 50 parts, the plaster prepared with this proportioning can have the elasticity of efficient recovery articuli intervertebrales place connective tissue, when degree or severe spondylopathy, cure rate can reach more than 90% in the treatment.Wherein, the formula consumption instant effect cure rate of Semen Strychni 20 parts, Flos Daturae 6 parts, Radix Aconiti Kusnezoffii 9 parts, Radix Aconiti 9 parts, 9 parts, Flos Carthami, Cortex Cinnamomi 5 parts, the Cortex Eucommiae 9 parts, Radix Aconiti Lateralis Preparata 9 parts, Radix Achyranthis Bidentatae 9 parts, Radix Saposhnikoviae 9 parts, 9 parts, Herba Ephedrae, Radix Angelicae Sinensis 9 parts, Cortex Acanthopancis 9 parts, Herba Asari 7 parts, Squama Manis scute 9 parts, Scolopendra 9 parts, Semen Impatientis 7 parts, Herba speranskiae tuberculatae 7 parts, Ramulus Cinnamomi 7 parts, Bufo siccus 55 parts, Scorpio 9 parts, Borneolum Syntheticum 9 parts, Camphora 50 parts is high, reaches 100% to treatment cervical spondylotic radiculopathy cure rate.
Compared with prior art, the beneficial effect that a kind of plaster for the treatment of spondylopathy of the present invention and preparation method thereof has is:
1, the plaster of this treatment spondylopathy effectively can treat spondylopathy, and the complication that spondylopathy causes, and reduction of patient is painful.The total effective rate of the plaster of this treatment spondylopathy can reach 93%.For the joint affected part pain instant effect that cervical spondylosis, lumbar spondylosis cause, can the misery of rapid recovery patient, can effect a radical cure after using the course for the treatment of.Have good therapeutic effect for spondylopathy complication, effective percentage can reach 95%.
2, the plaster of this treatment spondylopathy is for the inflammation of knee joint, elbow joint, carpal joint, finger-joint and articular nerve pain thereof, and all have good therapeutic effect, effective percentage can reach 98%.
Detailed description of the invention
Embodiment 1 ~ 5 is detailed description of the invention of the present invention's a kind of plaster for the treatment of spondylopathy of the present invention and preparation method thereof, and wherein embodiment 1 is most preferred embodiment.
embodiment 1
The present embodiment formula is made up of the raw material of following weight portion: Semen Strychni 20 parts, Flos Daturae 6 parts, Radix Aconiti Kusnezoffii 9 parts, Radix Aconiti 9 parts, 9 parts, Flos Carthami, Cortex Cinnamomi 5 parts, the Cortex Eucommiae 9 parts, Radix Aconiti Lateralis Preparata 9 parts, Radix Achyranthis Bidentatae 9 parts, Radix Saposhnikoviae 9 parts, 9 parts, Herba Ephedrae, Radix Angelicae Sinensis 9 parts, Cortex Acanthopancis 9 parts, Herba Asari 7 parts, Squama Manis scute 9 parts, Scolopendra 9 parts, Semen Impatientis 7 parts, Herba speranskiae tuberculatae 7 parts, Ramulus Cinnamomi 7 parts, Bufo siccus 55 parts, Scorpio 9 parts, Borneolum Syntheticum 9 parts, Camphora 50 parts, Colophonium 200 parts, Oleum sesami 60 ~ 80 parts.
The preparation method of the present embodiment is:
1) method for making of Colophonium substrate: the Colophonium taken by weight ratio, Oleum sesami are added in temperature control pot, kettle temperature is controlled at 95 ~ 110 DEG C, until melted completely by Colophonium, namely obtain Colophonium substrate after stirring;
2) Semen Strychni, Flos Daturae, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Carthami, Cortex Cinnamomi, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Radix Achyranthis Bidentatae, Radix Saposhnikoviae, Herba Ephedrae, Radix Angelicae Sinensis, Cortex Acanthopancis, Herba Asari, Squama Manis scute, Scolopendra, Semen Impatientis, Herba speranskiae tuberculatae, Ramulus Cinnamomi, Bufo siccus and Scorpio is claimed by weight ratio, it is dropped in Chinese medicine grinder respectively, 500 mesh sieves are crossed after pulverizing, mix homogeneously, obtains medicated powder; Borneolum Syntheticum, Camphora were pulverized respectively 150 orders and obtained Borneolum Syntheticum powder and camphor powder;
3) by step 2) medicated powder that obtains adds in the Colophonium substrate that step 1) obtains, keeps Colophonium substrate temperature 100 ~ 110 DEG C, after stirring, obtain paste in adition process;
4) paste is cooled to 50 ~ 55 DEG C, in paste, adds step 2) gained Borneolum Syntheticum powder and camphor powder, be uniformly mixed and obtain plaster mastic;
5) by plaster mastic 30 ~ 60 grams, be pressed into the cake of thickness 2 ~ 5mm, cake be put on non-woven fabrics, obtain final product.
embodiment 2
The present embodiment formula is made up of the raw material of following weight portion: Semen Strychni 20 parts, Flos Daturae 7 parts, Radix Aconiti Kusnezoffii 7 parts, Radix Aconiti 9 parts, 7 parts, Flos Carthami, Cortex Cinnamomi 6 parts, the Cortex Eucommiae 7 parts, Radix Aconiti Lateralis Preparata 9 parts, Radix Achyranthis Bidentatae 7 parts, Radix Saposhnikoviae 9 parts, 7 parts, Herba Ephedrae, Radix Angelicae Sinensis 9 parts, Cortex Acanthopancis 7 parts, Herba Asari 7 parts, Squama Manis scute 7 parts, Scolopendra 9 parts, Semen Impatientis 7 parts, Herba speranskiae tuberculatae 6 parts, Ramulus Cinnamomi 7 parts, Bufo siccus 50 parts, Scorpio 9 parts, Borneolum Syntheticum 7 parts, Camphora 45 parts, Colophonium 200 parts, Oleum sesami 50 parts.
The preparation method of the present embodiment is:
1) method for making of Colophonium substrate: the Colophonium taken by weight ratio, Oleum sesami are added in temperature control pot, kettle temperature is controlled at 100 ~ 110 DEG C, until melted completely by Colophonium, namely obtain Colophonium substrate after stirring;
2) Semen Strychni, Flos Daturae, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Carthami, Cortex Cinnamomi, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Radix Achyranthis Bidentatae, Radix Saposhnikoviae, Herba Ephedrae, Radix Angelicae Sinensis, Cortex Acanthopancis, Herba Asari, Squama Manis scute, Scolopendra, Semen Impatientis, Herba speranskiae tuberculatae, Ramulus Cinnamomi, Bufo siccus and Scorpio is claimed by weight ratio, it is dropped in Chinese medicine grinder respectively, 400 mesh sieves are crossed after pulverizing, mix homogeneously, obtains medicated powder; Borneolum Syntheticum, Camphora were pulverized respectively 100 orders and obtained Borneolum Syntheticum powder and camphor powder;
3) by step 2) medicated powder that obtains adds in the Colophonium substrate that step 1) obtains, keeps Colophonium substrate temperature 95 ~ 110 DEG C, after stirring, obtain paste in adition process;
4) paste is cooled to 55 ~ 60 DEG C, in paste, adds step 2) gained Borneolum Syntheticum powder and camphor powder, be uniformly mixed and obtain plaster mastic;
5) by plaster mastic 30 ~ 60 grams, be pressed into the cake of thickness 2 ~ 5mm, cake be put on non-woven fabrics, obtain final product.
embodiment 3
The present embodiment formula is made up of the raw material of following weight portion: Semen Strychni 18 parts, Flos Daturae 6 parts, Radix Aconiti Kusnezoffii 9 parts, Radix Aconiti 7 parts, 9 parts, Flos Carthami, Cortex Cinnamomi 5 parts, the Cortex Eucommiae 9 parts, Radix Aconiti Lateralis Preparata 7 parts, Radix Achyranthis Bidentatae 9 parts, Radix Saposhnikoviae 7 parts, 9 parts, Herba Ephedrae, Radix Angelicae Sinensis 7 parts, Cortex Acanthopancis 9 parts, Herba Asari 6 parts, Squama Manis scute 9 parts, Scolopendra 7 parts, Semen Impatientis 6 parts, Herba speranskiae tuberculatae 7 parts, Ramulus Cinnamomi 6 parts, Bufo siccus 60 parts, Scorpio 9 parts, Borneolum Syntheticum 9 parts, Camphora 50 parts, Colophonium 250 parts, Oleum sesami 85 parts.
The preparation method of the present embodiment is:
1) method for making of Colophonium substrate: the Colophonium taken by weight ratio, Oleum sesami are added in temperature control pot, kettle temperature is controlled at 95 ~ 100 DEG C, until melted completely by Colophonium, namely obtain Colophonium substrate after stirring;
2) Semen Strychni, Flos Daturae, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Carthami, Cortex Cinnamomi, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Radix Achyranthis Bidentatae, Radix Saposhnikoviae, Herba Ephedrae, Radix Angelicae Sinensis, Cortex Acanthopancis, Herba Asari, Squama Manis scute, Scolopendra, Semen Impatientis, Herba speranskiae tuberculatae, Ramulus Cinnamomi, Bufo siccus and Scorpio is claimed by weight ratio, it is dropped in Chinese medicine grinder respectively, 450 mesh sieves are crossed after pulverizing, mix homogeneously, obtains medicated powder; Borneolum Syntheticum, Camphora were pulverized respectively 80 orders and obtained Borneolum Syntheticum powder and camphor powder;
3) by step 2) medicated powder that obtains adds in the Colophonium substrate that step 1) obtains, keeps Colophonium substrate temperature 95 ~ 110 DEG C, after stirring, obtain paste in adition process;
4) paste is cooled to 55 ~ 60 DEG C, in paste, adds step 2) gained Borneolum Syntheticum powder and camphor powder, be uniformly mixed and obtain plaster mastic;
5) by plaster mastic 30 ~ 60 grams, be pressed into the cake of thickness 2 ~ 5mm, cake be put on non-woven fabrics, obtain final product.
embodiment 4
The present embodiment formula is made up of the raw material of following weight portion: Semen Strychni 15 parts, Flos Daturae 8 parts, Radix Aconiti Kusnezoffii 7 parts, Radix Aconiti 10 parts, 10 parts, Flos Carthami, Cortex Cinnamomi 5 parts, the Cortex Eucommiae 10 parts, Radix Aconiti Lateralis Preparata 10 parts, Radix Achyranthis Bidentatae 7 parts, Radix Saposhnikoviae 10 parts, 7 parts, Herba Ephedrae, Radix Angelicae Sinensis 7 parts, Cortex Acanthopancis 10 parts, Herba Asari 5 parts, Squama Manis scute 10 parts, Scolopendra 10 parts, Semen Impatientis 8 parts, Herba speranskiae tuberculatae 5 parts, Ramulus Cinnamomi 5 parts, Bufo siccus 20 parts, Scorpio 7 parts, Borneolum Syntheticum 10 parts, Camphora 30 parts, Colophonium 250 parts, Oleum sesami 150 parts.
The preparation method of the present embodiment is with embodiment 1.
embodiment 5
The present embodiment formula is made up of the raw material of following weight portion: Semen Strychni 20 parts, Flos Daturae 5 parts, Radix Aconiti Kusnezoffii 10 parts, Radix Aconiti 7 parts, 7 parts, Flos Carthami, Cortex Cinnamomi 8 parts, the Cortex Eucommiae 7 parts, Radix Aconiti Lateralis Preparata 7 parts, Radix Achyranthis Bidentatae 10 parts, Radix Saposhnikoviae 7 parts, 10 parts, Herba Ephedrae, Radix Angelicae Sinensis 10 parts, Cortex Acanthopancis 7 parts, Herba Asari 8 parts, Squama Manis scute 7 parts, Scolopendra 7 parts, Semen Impatientis 5 parts, Herba speranskiae tuberculatae 8 parts, Ramulus Cinnamomi 8 parts, Bufo siccus 60 parts, Scorpio 10 parts, Borneolum Syntheticum 7 parts, Camphora 60 parts, Colophonium 300 parts, Oleum sesami 100 parts.
The preparation method of the present embodiment is with embodiment 1.
clinical practice of the present invention is summarized as follows:
A kind of plaster heating for the treatment of spondylopathy of the present invention, after plaster mastic is softening, is affixed on affected part.Every note plaster docile time is 2 ~ 3 days, and 3 subsides are 1 course for the treatment of.Can continuously every using continuously or interval 1 ~ 2 day between the course for the treatment of.Less than ten years old children and anemia of pregnant woman are cautious use of.
By to using 1737 routine patients of plaster of the present invention to enter Clinical efficacy, chief complaint and symptom as follows:
Cervical spondylosis: neck is turned round pain, cervical pain, had the pins and needles, arm is numb, facial lightning pain, cervical curvature straighten, disease comprise in above symptom one or more.
Lumbar spondylosis: lumbago, have the pins and needles, low level lumbago, tired time waist ache or distending pain, the soreness of waist, reflexive lumbago, medial leg sensory deprivation, swollen and unable, the stiff sense of lumbar vertebra pain waist of waist acid, comprise in above symptom one or more.
Spondylopathy complication: dysphagia, dysphagia, neck heart syndrome, blood pressure raise or reduction, chest pain, lower extremity paralysis, to damping off, comprises one or more in above symptom.
Arthritis: the inflammation referring to knee joint, elbow joint, carpal joint, finger-joint.Clinical manifestation be joint red, swollen, hot, bitterly, dysfunction and joint deformity.
Curative effect judging standard: table 1 is the therapeutic effect added up after 3 ~ 4 courses for the treatment of.The total case statistical result of plaster in clinical treatment that in table 1, data obtain for embodiment 1 ~ 5.According to the improvement situation of above-mentioned symptom, be divided into whole alleviation, partial rcsponse and without alleviation, cure and all alleviated by patient suffers from each symptom; Effectively suffered from symptom partial rcsponse by patient, partial symptoms does not improve; It is invalid that by patient, to be suffered from symptom without any improvement.According to the above, total effective rate is whole cure rate and portion's obvious effective rate sum.When adding up: while suffering from cervical spondylosis or lumbar spondylosis as patient, also with the symptom of complication, so this patient is recorded as cervical spondylosis or lumbar spondylosis 1 example, spondylopathy complication 1 example; As patient suffers from cervical spondylosis or lumbar spondylosis, but the symptom that do not develop complications, so this patient is recorded as cervical spondylosis or lumbar spondylosis 1 example.
Table 1 uses a kind of statistical effect for the treatment of the plaster of spondylopathy of the present invention
Can be found out by table 1, in 3 ~ 4 courses for the treatment of, total cure rate can reach 85%, and effective percentage can reach 93%.Over the course for the treatment of applicant find plaster of the present invention for the pain of joint affected part, numb this kind of sense of discomfort respond well to treatment fast, docile this law invention plaster can be effective after 30 ~ 60 minutes, pain, the numb this kind of sense of discomfort of joint affected part disappear, alleviate the misery of patient, improve the treatment enthusiasm of patient.Secondly applicant finds through statistics: wherein, and embodiment 1 is in treatment cervical spondylotic radiculopathy 103 example, and cure rate can reach 100%.Applicant finds that the therapeutic effect of the complication that plaster of the present invention causes for spondylopathy is obvious over the course for the treatment of, can be effective after using 2nd ~ 3 hours first, after cervical spondylosis or lumbar spondylosis are cured, its complication also can be cured equally, improves the quality of life of patient.In upper table, case stops using the plaster for the treatment of spondylopathy of the present invention to start timing, after a year and a half, carries out tracking return visit: cure after further consultation in patient and occur without disease recurrent cases the 1503 example healing patients that upper table is cured.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (4)

1. treat the plaster of spondylopathy for one kind, it is characterized in that, be made up of the raw material of following weight portion: Semen Strychni 15 ~ 20 parts, Flos Daturae 5 ~ 8 parts, Radix Aconiti Kusnezoffii 7 ~ 10 parts, Radix Aconiti 7 ~ 10 parts, 7 ~ 10 parts, Flos Carthami, Cortex Cinnamomi 5 ~ 8 parts, the Cortex Eucommiae 7 ~ 10 parts, Radix Aconiti Lateralis Preparata 7 ~ 10 parts, Radix Achyranthis Bidentatae 7 ~ 10 parts, Radix Saposhnikoviae 7 ~ 10 parts, 7 ~ 10 parts, Herba Ephedrae, Radix Angelicae Sinensis 7 ~ 10 parts, Cortex Acanthopancis 7 ~ 10 parts, Herba Asari 5 ~ 8 parts, Squama Manis scute 7 ~ 10 parts, Scolopendra 7 ~ 10 parts, Semen Impatientis 5 ~ 8 parts, Herba speranskiae tuberculatae 5 ~ 8 parts, Ramulus Cinnamomi 5 ~ 8 parts, Bufo siccus 20 ~ 60 parts, Scorpio 7 ~ 10 parts, Borneolum Syntheticum 7 ~ 10 parts, Camphora 30 ~ 60 parts, Colophonium 200 ~ 300 parts, Oleum sesami 30 ~ 150 parts.
2. a kind of plaster for the treatment of spondylopathy according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: Semen Strychni 18 ~ 20 parts, Flos Daturae 6 ~ 7 parts, Radix Aconiti Kusnezoffii 7 ~ 9 parts, Radix Aconiti 7 ~ 9 parts, 7 ~ 9 parts, Flos Carthami, Cortex Cinnamomi 5 ~ 6 parts, the Cortex Eucommiae 7 ~ 9 parts, Radix Aconiti Lateralis Preparata 7 ~ 9 parts, Radix Achyranthis Bidentatae 7 ~ 9 parts, Radix Saposhnikoviae 7 ~ 9 parts, 7 ~ 9 parts, Herba Ephedrae, Radix Angelicae Sinensis 7 ~ 9 parts, Cortex Acanthopancis 7 ~ 9 parts, Herba Asari 6 ~ 7 parts, Squama Manis scute 7 ~ 9 parts, Scolopendra 7 ~ 9 parts, Semen Impatientis 6 ~ 7 parts, Herba speranskiae tuberculatae 6 ~ 7 parts, Ramulus Cinnamomi 6 ~ 7 parts, Bufo siccus 50 ~ 60 parts, Scorpio 7 ~ 9 parts, Borneolum Syntheticum 7 ~ 9 parts, Camphora 45 ~ 50 parts, Colophonium 200 ~ 250 parts, Oleum sesami 50 ~ 85 parts.
3. a kind of plaster for the treatment of spondylopathy according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: Semen Strychni 20 parts, Flos Daturae 6 parts, Radix Aconiti Kusnezoffii 9 parts, Radix Aconiti 9 parts, 9 parts, Flos Carthami, Cortex Cinnamomi 5 parts, the Cortex Eucommiae 9 parts, Radix Aconiti Lateralis Preparata 9 parts, Radix Achyranthis Bidentatae 9 parts, Radix Saposhnikoviae 9 parts, 9 parts, Herba Ephedrae, Radix Angelicae Sinensis 9 parts, Cortex Acanthopancis 9 parts, Herba Asari 7 parts, Squama Manis scute 9 parts, Scolopendra 9 parts, Semen Impatientis 7 parts, Herba speranskiae tuberculatae 7 parts, Ramulus Cinnamomi 7 parts, Bufo siccus 55 parts, Scorpio 9 parts, Borneolum Syntheticum 9 parts, Camphora 50 parts, Colophonium 200 parts, Oleum sesami 60 ~ 80 parts.
4. a kind of manufacture method for the treatment of the plaster of spondylopathy described in any one of claim 1 ~ 3, is characterized in that, adopts following steps:
1) method for making of Colophonium substrate: the Colophonium taken by weight ratio, Oleum sesami are added in temperature control pot, kettle temperature is controlled at 95 ~ 110 DEG C, until melted completely by Colophonium, namely obtain Colophonium substrate after stirring;
2) Semen Strychni, Flos Daturae, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Carthami, Cortex Cinnamomi, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Radix Achyranthis Bidentatae, Radix Saposhnikoviae, Herba Ephedrae, Radix Angelicae Sinensis, Cortex Acanthopancis, Herba Asari, Squama Manis scute, Scolopendra, Semen Impatientis, Herba speranskiae tuberculatae, Ramulus Cinnamomi, Bufo siccus and Scorpio is claimed by weight ratio, it is dropped in Chinese medicine grinder respectively, 400 ~ 500 mesh sieves are crossed after pulverizing, mix homogeneously, obtains medicated powder; Borneolum Syntheticum, Camphora were pulverized respectively 80 ~ 150 orders and obtained Borneolum Syntheticum powder and camphor powder;
3) by step 2) medicated powder that obtains adds in the Colophonium substrate that step 1) obtains, keeps Colophonium substrate temperature 95 ~ 110 DEG C, after stirring, obtain paste in adition process;
4) paste is cooled to 50 ~ 60 DEG C, in paste, adds step 2) gained Borneolum Syntheticum powder and camphor powder, be uniformly mixed and obtain plaster mastic;
5) by plaster mastic 30 ~ 60 grams, be pressed into the cake of thickness 2 ~ 5mm, cake be put on non-woven fabrics, obtain final product.
CN201511014096.8A 2015-12-31 2015-12-31 Plaster for treating spondylodynia and preparation method thereof Pending CN105456509A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201511014096.8A CN105456509A (en) 2015-12-31 2015-12-31 Plaster for treating spondylodynia and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201511014096.8A CN105456509A (en) 2015-12-31 2015-12-31 Plaster for treating spondylodynia and preparation method thereof

Publications (1)

Publication Number Publication Date
CN105456509A true CN105456509A (en) 2016-04-06

Family

ID=55594966

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201511014096.8A Pending CN105456509A (en) 2015-12-31 2015-12-31 Plaster for treating spondylodynia and preparation method thereof

Country Status (1)

Country Link
CN (1) CN105456509A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106620108A (en) * 2017-02-09 2017-05-10 周志强 Toxin eliminating and pain alleviating ointment
CN110960660A (en) * 2019-11-28 2020-04-07 广州市希丽生物科技服务有限公司 Traditional Chinese medicine plaster for dredging collaterals and removing stasis and preparation method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1359704A (en) * 2000-12-22 2002-07-24 牛品中 Process for preparing patch for treatment of cervicodynia
CN1895642A (en) * 2005-07-12 2007-01-17 侯保君 Traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain and preparation method thereof
CN102836177A (en) * 2012-09-13 2012-12-26 杜晓光 Traditional Chinese medicine preparation for treating osteopathia
CN103933141A (en) * 2014-04-03 2014-07-23 汪建华 Plaster for treating osteoarthritis, and preparation method thereof
CN104398718A (en) * 2014-11-06 2015-03-11 候纪海 Plaster for treating pains in neck, shoulder, waist and legs, and making method thereof
CN104815263A (en) * 2015-04-27 2015-08-05 朱道明 Plaster for treating osteoproliferation of cervical vertebra and lumbar vertebra

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1359704A (en) * 2000-12-22 2002-07-24 牛品中 Process for preparing patch for treatment of cervicodynia
CN1895642A (en) * 2005-07-12 2007-01-17 侯保君 Traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain and preparation method thereof
CN102836177A (en) * 2012-09-13 2012-12-26 杜晓光 Traditional Chinese medicine preparation for treating osteopathia
CN103933141A (en) * 2014-04-03 2014-07-23 汪建华 Plaster for treating osteoarthritis, and preparation method thereof
CN104398718A (en) * 2014-11-06 2015-03-11 候纪海 Plaster for treating pains in neck, shoulder, waist and legs, and making method thereof
CN104815263A (en) * 2015-04-27 2015-08-05 朱道明 Plaster for treating osteoproliferation of cervical vertebra and lumbar vertebra

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106620108A (en) * 2017-02-09 2017-05-10 周志强 Toxin eliminating and pain alleviating ointment
CN110960660A (en) * 2019-11-28 2020-04-07 广州市希丽生物科技服务有限公司 Traditional Chinese medicine plaster for dredging collaterals and removing stasis and preparation method thereof

Similar Documents

Publication Publication Date Title
CN104147577A (en) Plaster used for promoting generation of bone callus and treating fracture
CN101239132B (en) Strong bone-setting medicament for treating bone fracture and traumatic injury
CN101049430A (en) External ointment for treating bone fracture
CN105362711A (en) Plaster for treating pain of bone injury and preparation method thereof
CN103417780A (en) Bone fracture treatment plaster
CN101239131B (en) Blood-stasis-dissipating blood-circulation-promoting fast fracture-setting medicament
CN101264146A (en) Externally-applied Chinese herbal medicine for treating muscle and joint disease and preparation thereof
CN100431577C (en) Medicine for treating femoral head necrosis and femur neck fracture and preparation method thereof
CN103736069B (en) One is treated rheumatismal plaster and preparation method thereof
CN109276632A (en) A kind of Medical cold application and preparation method thereof
CN102626505A (en) Massaging paste based on Chinese medicinal herbs and preparation method thereof
CN104873851A (en) Internal and external traditional-Chinese-medicine composition for treating bedsore
CN101569738A (en) Plaster for treating mastitis, hyperplasia of mammary glands, breast lumps, join thydrops, traumatic injury, preparation method and application thereof
CN105456509A (en) Plaster for treating spondylodynia and preparation method thereof
CN114533831B (en) Traditional Chinese medicine composition with effects of warming middle-jiao, dispelling cold, eliminating dampness, promoting blood circulation, removing obstruction in channels and relieving pain and heat-covered bag thereof
CN104587206A (en) Medicament for treating bedsore and preparation method of medicament
CN101317942B (en) Bone-setting alcohol
CN103977367A (en) Traditional Chinese medicament for treating qi-stagnation blood-aggregation type bedsore and preparation method thereof
CN103223078A (en) Traditional Chinese medicine used for treating knee osteoarthritis through iontophoresis
CN102743550B (en) Medicine composition for accelerating healing after fracture surgery, preparation method and application
CN101954040A (en) Externally-applied medicament for treating hyperosteogeny and preparation method thereof
CN101797291B (en) Traditional Chinese medicine for treating osteoproliferation
CN101628063A (en) Externally-applied plaster for treating synovitis
CN104524080A (en) Traditional Chinese medicine preparation for treating injuries from falls, fractures, contusions and strains and preparation method
CN104491670A (en) Traditional Chinese medicine composition for treating chronic pelvic inflammatory disease

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20160406