CN103393953B - Traditional Chinese medicine ointment for promoting postoperative wound healing, and preparation method thereof - Google Patents
Traditional Chinese medicine ointment for promoting postoperative wound healing, and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine ointment for promoting postoperative wound healing, and a preparation method thereof. Raw materials for preparing effective components of the traditional Chinese medicine ointment comprise: balloonflower root, hibiscus mutabilis linn, cactus, angelica archang lica, hirsute gonostegia herb with root, spanishneedles herb, common bletilla tuber, cirsium japonicum, giant knotweed rhizome, wild aconite root, frankincense, dragon's blood, maifanite, tengyuch euonymus bark, common schizocapsa tuber and borneol. The traditional Chinese medicine ointment is prepared by adopting the modern advanced pharmaceutical technology, wherein the selected herbs have suitable compatibility, theories of the Chinese medical science and the modern medicine are met, effects of blood circulation activating, skin regeneration, heat clearing, pain relieving, sterilization and inflammation elimination can be provided, characteristics of wound granulation growth acceleration, wound membrane binding healing promotion, and no scar residue on the wound after healing are provided, and clinical applications confirm that the total efficiency is up to 95.6%, characteristics of safety, no toxic-side effect, and quick effect are provided, and the traditional Chinese medicine ointment is worthy of widely being used so as to promote postoperative wound healing.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of promote postoperative wound to heal Chinese medicine ointment and preparation method.
Background technology
Along with the development of modern medicine, the various disease of operative treatment has become a kind of important means of therapeutic treatment.Operation refer to utilize cutter, cut, the operation such as the medical apparatus and instruments such as pin excises patient's local body, stitching, cure or diagnose the illness, removing pathological tissues, damaged tissue repair, transplant organ, improves a kind of medical procedure of the function and morphology of body.
Medical operating can be divided into Sterile surgery, clean-contaminated operation, contaminated operation according to its otch.Sterile surgery relates to human body sterile region, surgical wound local NIP, not damaged; Clean-contaminated operation refers to and relates to lower respiratory tract, upper lower digestive tract, urogenital tract or the operation through above organ, posts and grows flora, may cause infection by contaminated operation wound during operation because operative site exists a large amount of human body; Contaminated operation refers to due to gastrointestinal tract, urinary tract, biliary tract body fluid overflows in a large number or open wound causes the serious tight dirty operation of surgical wound without expanding wound etc.Surgical wound is once by pathogen contamination, and be easy to produce and infect, even suppurate, severe patient even threatens the life of patient.
In addition, medical operating generally all carries out under narcotism, and after operation is carried out, anesthetic action disappears, and patient wound's hurt like hell very easily causes that the wound opened under the strain, then causes a series of post-operative complication.Therefore, after patient carries out medical operating, surgical wound needs to carry out special care.The large multipair postoperative patient of medical surgery of existence conditions carries out injection of antibiotics and anti-inflammation and analgesic drugs to alleviate patient's misery, reduces the occurrence probability of inflammation.Because Western medicine is large for the side effect of human body, and due to life-time service, pathogenic bacteria very easily forms Drug resistance, and curative effect is not remarkable.
Chinese medicine is as China's traditional medicine, and traumatism treatment with a long history, develops a kind of Chinese medicine ointment safely and effectively and help to solve the major subjects that postoperative wound healing problems has become a significantly study of pharmacy.
Summary of the invention
The invention provides a kind of promote postoperative wound to heal Chinese medicine ointment and preparation method, Chinese medicines of the present invention has effect of blood activating and promoting tissue regeneration, clearing away heat and alleviating pain, bactericidal antiphlogistic, wound granulation growth can be accelerated, promote to hinder conjunctiva healing, and after healing, scarless wound remains, and confirms through clinical practice, total effective rate is up to 95.6%, Atoxic side effect, instant effect, is worth being widely used in promoting postoperative wound healing.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Promote the Chinese medicine ointment that postoperative wound heals, the raw material composition parts by weight making described Chinese medicine ointment effective ingredient are:
Radix Platycodonis 45-75 part Hibisci Mutabilis 45-75 part Radix et Caulis Opuntiae Dillenii 45-75 part Radix Angelicae Dahuricae 45-75 part
Herba Gonostegiae hirtae 35-62 part Herba Bidentis Bipinnatae 35-60 part Pseudobulbus Bletillae (Rhizoma Bletillae) 28-54 part Radix Cirsii Japonici 28-54 part
Rhizoma Polygoni Cuspidati 25-52 part Radix Aconiti Kusnezoffii 23-52 part Olibanum 20-45 part Sanguis Draxonis 20-45 part
Maifanitum 15-35 part Rhizoma Euonymus 15-40 part Rhizoma Schizocapsae Plantagineae 15-40 part Borneolum Syntheticum 10-25 part.
Raw material composition and the parts by weight of making described Chinese medicine ointment effective ingredient are:
Radix Platycodonis 65 parts of Hibisci Mutabilis 65 parts of Radix et Caulis Opuntiae Dilleniis 65 parts of Radixs Angelicae Dahuricae 65 parts
Herba Gonostegiae hirtae 54 portions of Herba Bidentis Bipinnatae 52 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) 46 portions of Radix Cirsii Japonicis 46 parts
Rhizoma Polygoni Cuspidati 44 parts of Radix Aconiti Kusnezoffiis 44 parts of Olibanums 35 parts of Sanguis Draxonis 35 parts
Maifanitum 30 parts of Rhizoma Euonymus 30 parts of Rhizoma Schizocapsae Plantagineaes 30 parts of Borneolum Syntheticums 20 parts.
Raw material composition and the parts by weight of making described Chinese medicine ointment effective ingredient are:
Radix Platycodonis 57 parts of Hibisci Mutabilis 57 parts of Radix et Caulis Opuntiae Dilleniis 57 parts of Radixs Angelicae Dahuricae 57 parts
Herba Gonostegiae hirtae 48 portions of Herba Bidentis Bipinnatae 46 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) 39 portions of Radix Cirsii Japonicis 39 parts
Rhizoma Polygoni Cuspidati 36 parts of Radix Aconiti Kusnezoffiis 37 parts of Olibanums 30 parts of Sanguis Draxonis 30 parts
Maifanitum 25 parts of Rhizoma Euonymus 25 parts of Rhizoma Schizocapsae Plantagineaes 25 parts of Borneolum Syntheticums 16 parts.
Raw material composition and the parts by weight of making described Chinese medicine ointment effective ingredient are:
Radix Platycodonis 49 parts of Hibisci Mutabilis 49 parts of Radix et Caulis Opuntiae Dilleniis 49 parts of Radixs Angelicae Dahuricae 49 parts
Herba Gonostegiae hirtae 40 portions of Herba Bidentis Bipinnatae 40 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) 32 portions of Radix Cirsii Japonicis 32 parts
Rhizoma Polygoni Cuspidati 28 parts of Radix Aconiti Kusnezoffiis 30 parts of Olibanums 25 parts of Sanguis Draxonis 25 parts
Maifanitum 20 parts of Rhizoma Euonymus 20 parts of Rhizoma Schizocapsae Plantagineaes 20 parts of Borneolum Syntheticums 12 parts.
A preparation method for the Chinese medicine ointment promoting postoperative wound to heal, comprises following processing step:
(1) get Radix Platycodonis, Hibisci Mutabilis, Radix et Caulis Opuntiae Dillenii, Herba Gonostegiae hirtae and Rhizoma Schizocapsae Plantagineae to clean, dry, put into container, add the distilled water of 8-10 times amount, soak after 4-5 hour, boil 3-4 hour, extract; Again add 6-8 times amount distilled water, boil 2-3 hour, extract; Finally, add 4-6 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, reserved filtrate is for subsequent use;
(2) get Herba Bidentis Bipinnatae and Radix Cirsii Japonici to clean, cutting, mashes strand juice, filters, stays juice for subsequent use;
(3) get the Radix Angelicae Dahuricae, Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Radix Aconiti Kusnezoffii, Sanguis Draxonis and Maifanitum to clean, dry, grind into powder, cross 180 order fine powders, for subsequent use;
(4) get Olibanum to clean, put in pot to fry with slow fire and slightly see melting point to surface, slightly in yellow, take out after cooling, grind into powder, cross 120 order fine powders;
(5) get Rhizoma Euonymus cleaning, drying, mill with stone grinder, mill and add a small amount of water simultaneously, obtain extract for subsequent use;
(6) get Borneolum Syntheticum, grind into powder, add 95% alcoholic solution of 4 times amount, stir and make it to dissolve completely, filter, obtain filtrate for subsequent use;
(7) by the filtrate obtained by above-mentioned steps (1)-(6), juice, fine powder and extract mixing, utilize modern advanced pharmacy science and technology, make Chinese medicine ointment, be the Chinese medicine ointment of described promotion postoperative wound healing.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Platycodonis: bitter in the mouth, pungent, property is put down; Return lung meridian.Lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus." detailed outline " carries: " main aphtha of the mouth and tongue, Akamu swells and ache.”
Hibisci Mutabilis: taste is micro-pungent, cool in nature.Heat-clearing and toxic substances removing, detumescence and apocenosis, cooling blood for hemostasis.For cough due to lung-heat, menorrhagia, leucorrhea; Carbuncle furuncle is controlled in external, mastitis, lymphadenitis, parotitis, burn and scald, venom, traumatic injury.
Radix et Caulis Opuntiae Dillenii: bitter in the mouth, cool in nature; Enter the heart, lung, stomach three warp.Heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, benefiting stomach and stopping pain, antitussive.For taste-blindness rate, acute dysentery, cough; Mumps is controlled in external, mastitis, carbuncle furuncle and phyma poison, venom, burn and scald." Luchuan book on Chinese herbal medicine " carries: " eliminating inflammation and expelling toxin, evacuation of pus granulation promoting.Cure mainly carbuncle furuncle and phyma, cough.”
The Radix Angelicae Dahuricae: pungent, temperature; Attach to the lung and stomach meridians.Expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping.Profit blood vessels, expelling wind and cold, eliminating dampness and dredging channels, is widely used in the treatment of the diseases such as soft tissue contusion, hyperosteogeny, muscular strain, rheumatic myositis, fracture, costal chondritis, scapulohumeral periarthritis, intercostal neuralgia.The Radix Angelicae Dahuricae all has inhibitory action to escherichia coli, dysentery bacterium, Bacillus proteus, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus, vibrio cholera, Bacillus tuberculosis etc.
Herba Gonostegiae hirtae: sweet in the mouth, micro-hardship, property is flat, cool, nontoxic.Heat-clearing and toxic substances removing, spleen invigorating, hemostasis.Main treatment skin ulcer, carbuncle, scrofula, dysentery, women leucorrhea, infantile malnutrition, spits blood, traumatic hemorrhage." Yunnan Chinese herbal medicine " carries: " synthetism granulation promoting, antiinflammatory antidiarrheal.Control dysentery, dysmenorrhea.”
Herba Bidentis Bipinnatae: bitter in the mouth, cold nature.Heat-clearing and toxic substances removing, expelling wind and removing dampness, promoting blood circulation and detumescence.Cure mainly malaria, diarrhoea, dysentery, hepatitis, acute nephritis, stomachache, dysphagic, acute appendicitis, laryngopharynx swelling and pain, traumatic injury, snake bite and insect sting.Modern medicine study confirms, the ethanol immersion of Herba Bidentis Bipinnatae has bacteriostasis to gram-positive bacterium in vitro, and flower, stem also have bacteriostasis to staphylococcus aureus.
Pseudobulbus Bletillae (Rhizoma Bletillae): acrid in the mouth, hardship, sweet, puckery, cold nature; Return lung, liver, stomach warp.Tonifying the lung, hemostasis, detumescence, granulation promoting, sore.Control lung and hinder hemoptysis, epistaxis, incised wound is hemorrhage, swollen ulcer drug, canker sores, and soup fire is burnt, rhagadia manus et pedis." Bencao Tujing " carry: " control incised wound not to be recovered, in carbuncle side multiplex it." modern medicine study confirmation, it is active that Pseudobulbus Bletillae (Rhizoma Bletillae) can strengthen platelet factor III, significantly shortens clotting time and thrombinogen formation time, and suppress plasmin enzymatic activity, have anastalsis to local hemorrhage, its water decoction has antibacterial action.
Radix Cirsii Japonici: sweet in the mouth, hardship, cool in nature, nontoxic; GUIXIN, Liver Channel.Cure mainly haematemesis, epistaxis, hematuria, stranguria with blood, metrorrhagia, leukorrhagia, hemorrhoidal hamorrhage, acute appendicitis, carbuncle and ulcer toxic swelling, furuncle.Modern medicine study confirms, the aqueous solution of Radix Cirsii Japonici has anesthetic action; The generation of Radix Cirsii Japonici to thrombokinase has facilitation, and can suppress pathogenic bacteria generation.
Rhizoma Polygoni Cuspidati: mildly bitter flavor, cold nature; Return liver, gallbladder, lung meridian.Heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, postnatal blood stasis does not Xia ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, traumatic injury, carbuncle sore tumefacting virus.Modern medicine study confirms, Huzhang has obvious anastalsis to traumatic hemorrhage, and for oral administration also have anastalsis to upper gastrointestinal hemorrhage, and Rhizoma Polygoni Cuspidati extract has antipyretic effect, has convergence, protects from infection and antiinflammation to scald wound.
Radix Aconiti Kusnezoffii: acrid in the mouth, hardship, hot in nature, very toxic.Expelling wind and removing dampness, dispersing cold for relieving pain, opens expectorant, detumescence.Cure mainly anemofrigid-damp arthralgia, arthralgia, wind syndrome of head is had a headache, apoplectic dyscinesia, trusted subordinate's cold type of pain, and colic of cold type is had a pain, traumatic injury, swelling and pain due to blood stasis, carbuncle of yin nature toxic swelling; External narcotic analgesic.Modern medicine study confirms, the Radix Aconiti Kusnezoffii alkali that Radix Aconiti Kusnezoffii includes has local anesthesia effect, and can anti-inflammatory analgesic.
Olibanum: bitter in the mouth, property are pungent, warm; Enter the heart, liver, spleen channel.Invigorate blood circulation, circulation of qi promoting, pain relieving.Cure mainly the epigastric pain of the stasis blocking stagnation of QI, rheumatic arthralgia, traumatic injury, dysmenorrhea, puerperal abdonimal pain." detailed outline " carries: " all poison of eliminating carbuncle cellulitis, the heart is protected in Tuoli, and analgesic therapy of invigorating blood circulation, stretches muscle, controls married woman's difficult labour, injured." modern medicine study confirmation, Olibanum has analgesia bacteriostasis.
Sanguis Draxonis: sweet in the mouth, micro-salty, property is put down, mild toxicity; GUIXIN, Liver Channel.Dissipating blood stasis analgesic therapy, hemostasis, promoting tissue regeneration and ulcer healing.Cure mainly traumatic injury, ecchymoma due to internal injury, dysmenorrhea, postpartum stagnation is suffered from abdominal pain, continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time and hemorrhoid.Tang Materia Medica carries: " main the five internal organs pathogen, leukorrhagia, pain relieving, removing mass blood, gold creation meat.”
Maifanitum: sweet in the mouth, warm in nature, nontoxic; Return liver, stomach, kidney channel.Detoxicating and resolving stagnation of pathogens, removing the necrotic tissue and promoting granulation, except cold damp eliminating, the liver benefiting stomach invigorating, blood circulation promoting and blood stasis dispelling, diuresis fossil, life lengthening.Cure mainly carbuncle carbuncle on the back, acne, eczema, beriberi, miliaria, finger is chapped, chloasma, toothache, oral ulcer, rheumatic arthralgia, lumbago and backache, chronic hepatitis, gastritis, dysentery, diabetes, neurasthenia, wound is red and swollen, hypertension, senile sclerosis of blood vessels, tumor, lithangiuria.
Rhizoma Euonymus: property is put down, lightly seasoned; Enter Liver Channel.Hemostasia and promoting granulation, cures mainly knife injury.
Rhizoma Schizocapsae Plantagineae: bitter in the mouth, cold in nature, poisonous.Heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, regulating QI to relieve pain, preventing the attack (or recurrence) of malaria.For laryngopharynx swelling and pain, acute gastroenteritis, urinary tract infection, toothache, chronic gastritis, taste-blindness rate, rheumatic arthritis, menoxenia, malaria, traumatic injury; Sore swollen toxin is controlled in external, traumatic hemorrhage." choosing of Simao, Yunnan Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, anti-inflammatory analgetic.Control gastric and duodenal ulcers, hypertension, hepatitis, stomachache, scald, burn, skin infection.”
Borneolum Syntheticum: acrid in the mouth, hardship, cool in nature; Enter the heart, lung meridian.Logical all keys, loose stagnated fire, removing nebula improving eyesight, reducing swelling and alleviating pain, refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.Zhang Jingyue " book on Chinese herbal medicine just " carries: " the micro-sweet great Xin of taste, it is cool to ice to apply user, and the male power of gas is sharp.This is non-thermal, has the moon also in sun.Kind loose gas, loose blood, loose fire, loose stagnant, sensible, ward off evil, by trusted subordinate's pathogen.”
The present invention compared with prior art, has following beneficial effect:
Chinese medicine ointment of the present invention adopts modern advanced medical pharmaceutical technology to make, selected medical material compatibility is suitable, meets the traditional Chinese medical science and modern medicine theory, has effect of blood activating and promoting tissue regeneration, clearing away heat and alleviating pain, bactericidal antiphlogistic, wound granulation growth can be accelerated, promote the healing of wound conjunctiva, and after healing, scarless wound remains, and confirms through clinical practice, total effective rate is up to 95.6%, safe without toxic side effect, instant effect, is worth being widely used in promoting postoperative wound healing.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine ointment effective ingredient of the present invention and weight are:
Radix Platycodonis 70g Hibisci Mutabilis 70g Radix et Caulis Opuntiae Dillenii 70g Radix Angelicae Dahuricae 70g
Herba Gonostegiae hirtae 58g Herba Bidentis Bipinnatae 58g Pseudobulbus Bletillae (Rhizoma Bletillae) 52g Radix Cirsii Japonici 52g
Rhizoma Polygoni Cuspidati 49g Radix Aconiti Kusnezoffii 48g Olibanum 40g Sanguis Draxonis 40g
Maifanitum 33g Rhizoma Euonymus 35g Rhizoma Schizocapsae Plantagineae 35g Borneolum Syntheticum 23g.
The preparation method of Chinese medicine ointment of the present invention, comprises following processing step:
(1) get Radix Platycodonis, Hibisci Mutabilis, Radix et Caulis Opuntiae Dillenii, Herba Gonostegiae hirtae and Rhizoma Schizocapsae Plantagineae to clean, dry, put into container, add the distilled water of 8-10 times amount, soak after 4-5 hour, boil 3-4 hour, extract; Again add 6-8 times amount distilled water, boil 2-3 hour, extract; Finally, add 4-6 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, reserved filtrate is for subsequent use;
(2) get Herba Bidentis Bipinnatae and Radix Cirsii Japonici to clean, cutting, mashes strand juice, filters, stays juice for subsequent use;
(3) get the Radix Angelicae Dahuricae, Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Radix Aconiti Kusnezoffii, Sanguis Draxonis and Maifanitum to clean, dry, grind into powder, cross 180 order fine powders, for subsequent use;
(4) get Olibanum to clean, put in pot to fry with slow fire and slightly see melting point to surface, slightly in yellow, take out after cooling, grind into powder, cross 120 order fine powders;
(5) get Rhizoma Euonymus cleaning, drying, mill with stone grinder, mill and add a small amount of water simultaneously, obtain extract for subsequent use;
(6) get Borneolum Syntheticum, grind into powder, add 95% alcoholic solution of 4 times amount, stir and make it to dissolve completely, filter, obtain filtrate for subsequent use;
(7) by the filtrate obtained by above-mentioned steps (1)-(6), juice, fine powder and extract mixing, utilize modern advanced pharmacy science and technology, make Chinese medicine ointment, be the Chinese medicine ointment of described promotion postoperative wound healing.
Usage and dosage: external-applied ointment, uniform application is in wound for cream of getting it filled (selecting ointment amount according to wound length), and within every four hours, smear once, within seven days, be a course for the treatment of, a course for the treatment of gets final product healing of wound, continues use and can dispel operative scar two to three courses for the treatment of.
Embodiment 2
The raw material composition of Chinese medicine ointment effective ingredient of the present invention and weight are:
Radix Platycodonis 65g Hibisci Mutabilis 65g Radix et Caulis Opuntiae Dillenii 65g Radix Angelicae Dahuricae 65g
Herba Gonostegiae hirtae 54g Herba Bidentis Bipinnatae 52g Pseudobulbus Bletillae (Rhizoma Bletillae) 46g Radix Cirsii Japonici 46g
Rhizoma Polygoni Cuspidati 44g Radix Aconiti Kusnezoffii 44g Olibanum 35g Sanguis Draxonis 35g
Maifanitum 30g Rhizoma Euonymus 30g Rhizoma Schizocapsae Plantagineae 30g Borneolum Syntheticum 20g.
The present embodiment Chinese medicine ointment preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine ointment effective ingredient of the present invention and weight are:
Radix Platycodonis 57g Hibisci Mutabilis 57g Radix et Caulis Opuntiae Dillenii 57g Radix Angelicae Dahuricae 57g
Herba Gonostegiae hirtae 48g Herba Bidentis Bipinnatae 46g Pseudobulbus Bletillae (Rhizoma Bletillae) 39g Radix Cirsii Japonici 39g
Rhizoma Polygoni Cuspidati 36g Radix Aconiti Kusnezoffii 37g Olibanum 30g Sanguis Draxonis 30g
Maifanitum 25g Rhizoma Euonymus 25g Rhizoma Schizocapsae Plantagineae 25g Borneolum Syntheticum 16g.
The present embodiment Chinese medicine ointment preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine ointment effective ingredient of the present invention and weight are:
Radix Platycodonis 49g Hibisci Mutabilis 49g Radix et Caulis Opuntiae Dillenii 49g Radix Angelicae Dahuricae 49g
Herba Gonostegiae hirtae 40g Herba Bidentis Bipinnatae 40g Pseudobulbus Bletillae (Rhizoma Bletillae) 32g Radix Cirsii Japonici 32g
Rhizoma Polygoni Cuspidati 28g Radix Aconiti Kusnezoffii 30g Olibanum 25g Sanguis Draxonis 25g
Maifanitum 20g Rhizoma Euonymus 20g Rhizoma Schizocapsae Plantagineae 20g Borneolum Syntheticum 12g.
The present embodiment Chinese medicine ointment preparation method processing step and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine ointment promoting postoperative wound healing, select just complete patient 180 example of operation to carry out clinical observation, patient is divided into two groups at random, treatment group 90 example, wherein man 45 example, women 45 example, age 5-60 year, 32.1 years old mean age, course of disease 1-5 days, average 1.3 days; Matched group 90 example, wherein male 46 example, women 44 example, age 6-58 year, 31.8 years old mean age, course of disease 1-5 days, average 1.2 days.Two groups of patient's postoperative wounds are basically identical, without significant difference, have comparability, keep on a diet all on request for two groups.
2, treatment group patient uses Chinese medicine ointment of the present invention, getting it filled, uniform application is in wound for cream (selecting ointment amount according to wound length), and within every four hours, smearing once, seven days is a course for the treatment of, a course for the treatment of gets final product healing of wound, continues use and can dispel operative scar two to three courses for the treatment of; Matched group injection drug for diminishing inflammation and antibiosis.
3, Outcome measure:
(1) effective: post-operative wound healed rapidly in 7 days, after healing, cicatrix fades away.
(2) take a turn for the better: wound healing is slow, healing time 7-15 days, after healing, skin leaves slight cicatrix.
(3) invalid: operation wound heal was more than 15 days, and in agglutination, have performance of suppurating, after healing, skin leaves cicatrix.
4, therapeutic outcome:
Treatment group: effective 48 examples, take a turn for the better 38 examples, and invalid 4 examples, total effective rate is 95.6%.
Matched group: effective 26 examples, take a turn for the better 39 examples, and without turning 25 examples, total effective rate is 72.2%.
Above result display, the total effective rate for the treatment of group is apparently higher than matched group.
Model case is illustrated:
1, field, man, 13 years old, student, people from Linyi, Shandong.Before half a year, suffer from acute appendicitis, carry out operative treatment, after operation terminates, uses Chinese medicine ointment of the present invention to smear surgical wound place, use 6 days, namely wound heals, continuation 2 courses for the treatment of of use, and cicatrix that wound stays disappears, and period, wound was without suppuration.
2, gold certain, female, 27 years old, guide, people from Dalian.Leg open fracture, post-operative wound stylolite suppurates to some extent, uses Chinese medicine ointment of the present invention 7 days, wound healing, continues 2 courses for the treatment of of use, and scarless wound remains, and period, wound suppuration was without recurrence.
3, the Qin, female, 45 years old, workman, Pingliang, Gansu people.Suffer from breast cancer late period, do chest resection operation, four courses for the treatment of of postoperative use Chinese medicine ointment of the present invention, period has no wound suppuration, and wound healing is fast, and healing status is good, and after using, scarless wound remains, and the cloudy day rains without scratchiness.
4, Chen, man, 65 years old, peasant, people from Xi'an, Shaanxi.Did inguinal hernia prosthesis before three months, postoperative Chinese medicine ointment of the present invention used to wound, use 8 days wound healings, continue to use to 3 the course for the treatment of scarless wound remain, period has no postoperative wound and suppurates.
Claims (5)
1. promote to it is characterized in that the Chinese medicine ointment that postoperative wound heals: raw material composition and the parts by weight of making described Chinese medicine ointment effective ingredient are:
Radix Platycodonis 45-75 part Hibisci Mutabilis 45-75 part Radix et Caulis Opuntiae Dillenii 45-75 part Radix Angelicae Dahuricae 45-75 part
Herba Gonostegiae hirtae 35-62 part Herba Bidentis Bipinnatae 35-60 part Pseudobulbus Bletillae (Rhizoma Bletillae) 28-54 part Radix Cirsii Japonici 28-54 part
Rhizoma Polygoni Cuspidati 25-52 part Radix Aconiti Kusnezoffii 23-52 part Olibanum 20-45 part Sanguis Draxonis 20-45 part
Maifanitum 15-35 part Rhizoma Euonymus 15-40 part Rhizoma Schizocapsae Plantagineae 15-40 part Borneolum Syntheticum 10-25 part.
2. a kind of Chinese medicine ointment promoting postoperative wound to heal according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine ointment effective ingredient are:
Radix Platycodonis 65 parts of Hibisci Mutabilis 65 parts of Radix et Caulis Opuntiae Dilleniis 65 parts of Radixs Angelicae Dahuricae 65 parts
Herba Gonostegiae hirtae 54 portions of Herba Bidentis Bipinnatae 52 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) 46 portions of Radix Cirsii Japonicis 46 parts
Rhizoma Polygoni Cuspidati 44 parts of Radix Aconiti Kusnezoffiis 44 parts of Olibanums 35 parts of Sanguis Draxonis 35 parts
Maifanitum 30 parts of Rhizoma Euonymus 30 parts of Rhizoma Schizocapsae Plantagineaes 30 parts of Borneolum Syntheticums 20 parts.
3. a kind of Chinese medicine ointment promoting postoperative wound to heal according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine ointment effective ingredient are:
Radix Platycodonis 57 parts of Hibisci Mutabilis 57 parts of Radix et Caulis Opuntiae Dilleniis 57 parts of Radixs Angelicae Dahuricae 57 parts
Herba Gonostegiae hirtae 48 portions of Herba Bidentis Bipinnatae 46 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) 39 portions of Radix Cirsii Japonicis 39 parts
Rhizoma Polygoni Cuspidati 36 parts of Radix Aconiti Kusnezoffiis 37 parts of Olibanums 30 parts of Sanguis Draxonis 30 parts
Maifanitum 25 parts of Rhizoma Euonymus 25 parts of Rhizoma Schizocapsae Plantagineaes 25 parts of Borneolum Syntheticums 16 parts.
4. a kind of Chinese medicine ointment promoting postoperative wound to heal according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine ointment effective ingredient are:
Radix Platycodonis 49 parts of Hibisci Mutabilis 49 parts of Radix et Caulis Opuntiae Dilleniis 49 parts of Radixs Angelicae Dahuricae 49 parts
Herba Gonostegiae hirtae 40 portions of Herba Bidentis Bipinnatae 40 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) 32 portions of Radix Cirsii Japonicis 32 parts
Rhizoma Polygoni Cuspidati 28 parts of Radix Aconiti Kusnezoffiis 30 parts of Olibanums 25 parts of Sanguis Draxonis 25 parts
Maifanitum 20 parts of Rhizoma Euonymus 20 parts of Rhizoma Schizocapsae Plantagineaes 20 parts of Borneolum Syntheticums 12 parts.
5. a preparation method for the Chinese medicine ointment promoting postoperative wound to heal as described in any one of claim 1-4, is characterized in that: comprise following processing step:
(1) get Radix Platycodonis, Hibisci Mutabilis, Radix et Caulis Opuntiae Dillenii, Herba Gonostegiae hirtae and Rhizoma Schizocapsae Plantagineae to clean, dry, put into container, add the distilled water of 8-10 times amount, soak after 4-5 hour, boil 3-4 hour, extract; Again add 6-8 times amount distilled water, boil 2-3 hour, extract; Finally, add 4-6 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, reserved filtrate is for subsequent use;
(2) get Herba Bidentis Bipinnatae and Radix Cirsii Japonici to clean, cutting, mashes strand juice, filters, stays juice for subsequent use;
(3) get the Radix Angelicae Dahuricae, Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Radix Aconiti Kusnezoffii, Sanguis Draxonis and Maifanitum to clean, dry, grind into powder, cross 180 order fine powders, for subsequent use;
(4) get Olibanum to clean, put in pot to fry with slow fire and slightly see melting point to surface, slightly in yellow, take out after cooling, grind into powder, cross 120 order fine powders;
(5) get Rhizoma Euonymus cleaning, drying, mill with stone grinder, mill and add a small amount of water simultaneously, obtain extract for subsequent use;
(6) get Borneolum Syntheticum, grind into powder, add 95% alcoholic solution of 4 times amount, stir and make it to dissolve completely, filter, obtain filtrate for subsequent use;
(7) by the filtrate obtained by above-mentioned steps (1)-(6), juice, fine powder and extract mixing, make Chinese medicine ointment, be the Chinese medicine ointment of described promotion postoperative wound healing.
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| CN105232856B (en) * | 2015-11-16 | 2018-08-14 | 张少峰 | A kind of pharmaceutical composition and its application for postoperative wound healing |
| CN105617273A (en) * | 2016-02-19 | 2016-06-01 | 季新玲 | Pharmaceutic preparation for promoting wound healing and application thereof |
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| CN106728358A (en) * | 2017-02-16 | 2017-05-31 | 牡丹江医学院 | A kind of Chinese medicine composition of promotion wound healing after operation |
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| CN109200220A (en) * | 2018-11-29 | 2019-01-15 | 吴斌 | A kind for the treatment of of wounds Chinese medicine composition and preparation method thereof |
| CN109350634A (en) * | 2018-12-10 | 2019-02-19 | 河北中医学院 | A kind of Chinese medicine composition and preparation method thereof for promoting wound healing |
| TW202122102A (en) * | 2019-12-10 | 2021-06-16 | 蔡禮安 | Plant extracts and preparation method thereof |
| CN114984125A (en) * | 2022-07-05 | 2022-09-02 | 贵州省人民医院 | Medicine for promoting wound healing and preparation method thereof |
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| CN1895485A (en) * | 2006-06-22 | 2007-01-17 | 贾付成 | Medicine for treating burn and scald |
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