CN104435843A - Local anesthetic for surgical incisions - Google Patents
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/855—Clerodendrum, e.g. glorybower
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
Abstract
The invention belongs to the technical field of traditional Chinese medicine and in particular relates to a local anesthetic for surgical incisions. The local anesthetic is prepared from the following traditional Chinese medicine raw materials in parts by weight: 5-15 parts of hindu datura flower, 5-15 parts of henbane, 3-6 parts of Chinese Cherry, 5-8 parts of corydalis tuber, 5-10 parts of panax pseudoginseng, 3-6 parts of schizonepeta spike, 5-8 parts of erigeron breviscapus, 5-10 parts of rhizoma corydalis, 3-6 parts of bittersweet fruit, 3-6 parts of myrrh, 5-10 parts of blackspiked lovegrass herb with root, 3-6 parts of plant soot, 5-10 parts of passion flower, 5-8 parts of pearl powder, 5-8 parts of folium isatidis and 5-8 parts of liquorice. The preparation method comprises the following steps: preparing a dressing, and bandaging the dressing on the surgical incisions by using local anesthetic fibers. The effects of anesthetizing, relieving pain, performing spasmolysis and checking convulsions in the traditional Chinese medicine are compatible with the effects of drawing out poison, promoting granulation, removing stasis and relieving pain, the prepared dressing is bound to the surgical incisions are bandaged with the dressing made from the local anesthetic fibers, and the effects of continuously anesthetizing, relieving pain and promoting wound healing are achieved.
Description
Technical field
The invention belongs to Chinese medicine anaesthesia technology field, particularly a kind of local anesthetic for operative incision.
Background technology
Local anesthetic refer to those in the limited range of human body can temporarily, completely, reversibly block nerves conduction, namely certain part of human body is lost sensibility, so that the medicine that surgical operation carries out realizing under the situation that do not disappear.The local anaesthesia method of current employing has: such as carry out injecting or quiet note local anesthetic, but the method is often because the disposable concentration entering human body is high, and side effect that is that produce is large, has the limitation that medical treatment cost is high, curative effect is short simultaneously; Another kind method local anesthesia fiber (local anaesthesia fiber) is made dressing wrapping or sticks on human body wound mouth, play local anesthetic action, but mostly containing hormone and synthetic medicament in its component of the anaesthetic added, life-time service can bring injury in various degree to human body.
Chinese patent (CN102861153A) discloses a kind of local anesthetic, is made up of pure Chinese medicine, but infiltration is slow, zest is large, be unfavorable for that operative incision heals, and is not suitable for and anaesthetizes operative incision, and actual popularization has certain restriction.
Summary of the invention
The object of this invention is to provide a kind of local anesthetic for operative incision, by the effect that the analgesia of Chinese medicine, spasmolytic are only jerked, compatibility is with the effect of removing toxic substances and promoting tissue regeneration, the silt pain relieving that disappears, adopting local anesthesia fiber to make dressing wraps up in operative incision, reaches continuous narcosis analgesia, promotes the effect of wound healing.
The invention provides a kind of local anesthetic for operative incision, formulated by the raw material of Chinese medicine of following parts by weight: Flos Daturae 5 ~ 15 parts, Semen Hyoscyami 5 ~ 15 parts, seven lis of sons 3 ~ 6 parts, Rhizoma Corydalis 5 ~ 8 parts, Radix Notoginseng 5 ~ 10 parts, Herba Schizonepetae 3 ~ 6 parts, Herba Erigerontis 5 ~ 8 parts, Rhizoma Corydalis 5 ~ 10 parts, Fructus Solani Lyrati 3 ~ 6 parts, Myrrha 3 ~ 6 parts, Radix Cyanotis vagae 5 ~ 10 parts, Pulvis Fumi Carbonisatus 3 ~ 6 parts, Herba Passiflorae Caeruleae 5 ~ 10 parts, Margarita powder 5 ~ 8 parts, Folium Isatidis 5 ~ 8 parts, 5 ~ 8 parts, Radix Glycyrrhizae.
More preferably formulated by the raw material of Chinese medicine of following parts by weight: Flos Daturae 12 parts, Semen Hyoscyami 10 parts, seven lis of sons 5 parts, Rhizoma Corydalis 7 parts, Radix Notoginseng 7 parts, Herba Schizonepetae 5 parts, Herba Erigerontis 6 parts, Rhizoma Corydalis 7 parts, Fructus Solani Lyrati 4 parts, Myrrha 5 parts, Radix Cyanotis vagae 8 parts, Pulvis Fumi Carbonisatus 5 parts, Herba Passiflorae Caeruleae 7 parts, Margarita powder 6 parts, Folium Isatidis 6 parts, 6 parts, Radix Glycyrrhizae.
Preparation method is made up of following steps: take raw material of Chinese medicine by above-mentioned weight portion, medicine except Margarita powder is put into 75% ethanol, ethanol did not have medical material 3 ~ 4cm, soak after 12 ~ 24 hours and take out, mash, dressing is made, with local anesthesia stapling at operative incision after mixing homogeneously with Margarita powder.
Pharmacology analysis:
Flos Daturae: acrid in the mouth, warm in nature, poisonous; Effect relieving cough and asthma, pain relieving is calm; Asthma and cough, coldness and pain in the epigastrium, rheumatic arthralgia, children's's intermittent infantile convulsion; Surgical anesthesia.Modern pharmacology proves, it has certain analgesic activity, and can strengthen the analgesic activity of dolantin, and the threshold of pain that antagonism norepinephrine intracerebroventricular injection causes reduces and the weakening of dolantin analgesic activity.
Semen Hyoscyami: warm in nature, bitter in the mouth is pungent, enters the heart, stomach, liver three warp, poisonous, has the effect of determining epilepsy, pain relieving.Modern pharmacological research shows, Semen Hyoscyami contains alkaloid, is mainly hyoscyamine, atropine and scopolamine, and reasonable volume has obvious relexation to smooth muscle, and energy elevated intraocular pressure and paralysis accommodation, also can be used for the poisoning severe arrhythmia caused of antimony agent.
Seven lis of sons: function cures mainly suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight is antipruritic.Dizzy for having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus.
Rhizoma Corydalis: nature and flavor are pungent, bitter, temperature, nontoxic; Return liver, stomach, the heart, lung, spleen channel.Function is invigorated blood circulation, dissipating blood stasis, regulates the flow of vital energy, pain relieving; Cure mainly all pains of trusted subordinate's waist knee joint, menoxenia, lump in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.
Radix Notoginseng: sweet in the mouth, micro-hardship, warm in nature, return lung, stomach, the heart, liver, large intestine channel.Function hemostasis dissipating blood stasis, subduing swelling and relieving pain, hemopoietic of enriching blood.Cure mainly obstruction of qi in the chest and cardialgia, blood stasis amenorrhea, lump in the abdomen, dysmenorrhea, postnatal blood stasis is suffered from abdominal pain, and spits blood, epistaxis, spitting of blood, metrorrhagia, traumatic hemorrhage, treating swelling and pain by traumatic injury, sore and toxic etc.Radix Notoginseng can be led to and can be mended, and can fall apart and can receive.
Herba Schizonepetae: function cures mainly the loose wind that induces sweat, rash.For flu, headache, measles, rubella, skin infection from the beginning of.Parch to black treating hematochezia, metrorrhagia, puerperal blood faints.
Herba Erigerontis: energy dredge the meridian passage and blood circulation promoting and blood stasis dispelling, expansion of cerebral vascular, reduction vascular resistance, improve cerebral circulation, increase heart and brain blood flow, improve immunologic function, cold in nature, micro-hardship, Gan Wenxin, have effect of be slightly cold removing toxic substances, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, dredge the meridian passage, anti-inflammatory analgetic.
Rhizoma Corydalis: warm in nature, acrid in the mouth is bitter, enters the heart, spleen, liver, lung, is the quality goods of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, is especially world-famous for effect of pain relieving.Li Shizhen (1518-1593 A.D.) concludes Rhizoma Corydalis in Compendium of Material Medica " invigorate blood circulation, regulate the flow of vital energy, pain relieving, diuresis " four large effects, and praises highly Rhizoma Corydalis " can the stagnation of QI in promoting the circulation of blood, stasis in gas, therefore specially control upper and lower all pains all over the body ".
Fructus Solani Lyrati: acid, flat, nontoxic.Control conjunctival congestion, toothache.
Myrrha: bitter, pungent is flat; Enter liver, spleen, the heart, kidney channel.Function hair growing, speckle dispelling disappears trace, and softening the hard mass is except tumor, and except tinea more wound, teeth consolidating is good for gum, removing toxic substances etc.; Cure mainly alopecia capillary, black spot bruise, verruca plana, various eczema, gingiva is rotten to the corn, and poisonous insect stings wound etc.
Radix Cyanotis vagae: sweet is flat.Function cures mainly dispelling, collateral-activating, inducing diuresis and reducing edema, moves back weakness.For rheumatic arthritis, lumbago and skelalgia, oedema due to nephritis, deficiency-heat is not moved back; Eczema is controlled in external, tinea pedis, knife injury.
Pulvis Fumi Carbonisatus: nature and flavor are pungent, temperature; Enter liver, lung, stomach warp.Function is stopped blooding, removing food stagnancy, sterilizing powdered medicine fire; Cure mainly haematemesis, epistaxis, have blood in stool, metrorrhagia, leukorrhagia, food stagnation, dysentery, jaundice, laryngopharynx swelling and pain, aphtha of the mouth and tongue, ecthyma, white bareheaded skin ulcer, traumatic hemorrhage.
Herba Passiflorae Caeruleae: warm in nature, bitter in the mouth is nontoxic.For neuralgia, insomnia, the disease such as menstrual pain and dysentery, has anesthesia and calmness.
Margarita powder: salty in the mouth is sweet cold nontoxic, relieving palpitation point order; Margarita is coated with face, makes us moist good color.Be coated with brothers, peeling skin hangnail; Pendant expectorant, except speckle, antidiarrheal; Except children's's fever (of children) accompanied by fear, peace soul; Only to pass out semen nebulousurine, separate pox and treat poison.
Folium Isatidis: bitter in the mouth is Great Cold, nontoxic; Enter liver, the heart, stomach warp.Function heat clearing away, removing toxic substances, removing heat from blood, hemostasis.Cure mainly epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas, spit blood, epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.
Radix Glycyrrhizae: sweet in the mouth, property is put down; Enter spleen, stomach, lung meridian; Function invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, clear throat, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Chinese medicine of the present invention, the effect of only being jerked by the analgesia of Chinese medicine, spasmolytic, compatibility, with the effect of removing toxic substances and promoting tissue regeneration, the silt pain relieving that disappears, adopts local anesthesia fiber to make dressing and wraps up in operative incision, reaches continuous narcosis analgesia, promotes the effect of wound healing.
Outcome measure:
Effective: in use procedure, operative incision pain disappears, and wound healing is all right, has no adverse reaction and malaise symptoms;
Effective: in use procedure, operative incision pain obviously reduces, and wound healing is all right, has no adverse reaction and malaise symptoms;
Invalid: in use procedure, operative incision pain does not alleviate, patients' neural's consciousness is under some influence, and has ill symptoms to occur.
Therapeutic outcome: use to 562 postoperative patients, changes once, within 5 days, is a course for the treatment of for 1 day.After using 1 course for the treatment of Chinese medicine of the present invention, effective 550 examples, account for 97.9%, and effective 10 examples, account for 1.8%, and invalid 2 examples, account for 0.3%.
Attached several routine case is described further:
Case 1: king so-and-so, female, 28 years old, cuts because of side and causes operative incision in natural labor process, after producing, Episiomy Wounds pain is strong, wound healing is slow, serious obstruction postpartum recovery, gives local anesthetic of the present invention then, carries out continuous narcosis to operative incision, in use procedure, incision pain sense disappears, and after 1 course for the treatment of, it is good that wound healing is cut in side.
Case 2: Zhao so-and-so, man, 26 years old, after carrying out operation for appendicitis, there is the situation of inflammation, disunion in operative incision, with having an intense pain, then give local anesthetic of the present invention, continuous narcosis is carried out to operative incision, in use procedure, incision pain sense disappears, and after 1 course for the treatment of, operative incision healing is good.
Detailed description of the invention
Embodiment 1:
For a local anesthetic for operative incision, formulated by the raw material of Chinese medicine of following parts by weight: Flos Daturae 12 parts, Semen Hyoscyami 10 parts, seven lis of sons 5 parts, Rhizoma Corydalis 7 parts, Radix Notoginseng 7 parts, Herba Schizonepetae 5 parts, Herba Erigerontis 6 parts, Rhizoma Corydalis 7 parts, Fructus Solani Lyrati 4 parts, Myrrha 5 parts, Radix Cyanotis vagae 8 parts, Pulvis Fumi Carbonisatus 5 parts, Herba Passiflorae Caeruleae 7 parts, Margarita powder 6 parts, Folium Isatidis 6 parts, 6 parts, Radix Glycyrrhizae.
Preparation method is made up of following steps: take raw material of Chinese medicine by above-mentioned weight portion, medicine except Margarita powder is put into 75% ethanol, ethanol did not have medical material 3.5cm, soak after 18 hours and take out, mash, dressing is made, with local anesthesia stapling at operative incision after mixing homogeneously with Margarita powder.
Embodiment 2:
For a local anesthetic for operative incision, formulated by the raw material of Chinese medicine of following parts by weight: Flos Daturae 5 parts, Semen Hyoscyami 15 parts, seven lis of sons 3 parts, Rhizoma Corydalis 8 parts, Radix Notoginseng 5 parts, Herba Schizonepetae 6 parts, Herba Erigerontis 5 parts, Rhizoma Corydalis 10 parts, Fructus Solani Lyrati 3 parts, Myrrha 6 parts, Radix Cyanotis vagae 5 parts, Pulvis Fumi Carbonisatus 6 parts, Herba Passiflorae Caeruleae 5 parts, Margarita powder 8 parts, Folium Isatidis 5 parts, 8 parts, Radix Glycyrrhizae.
Preparation method is made up of following steps: take raw material of Chinese medicine by above-mentioned weight portion, medicine except Margarita powder is put into 75% ethanol, ethanol did not have medical material 3cm, soak after 12 hours and take out, mash, dressing is made, with local anesthesia stapling at operative incision after mixing homogeneously with Margarita powder.
Embodiment 3:
For a local anesthetic for operative incision, formulated by the raw material of Chinese medicine of following parts by weight: Flos Daturae 15 parts, Semen Hyoscyami 5 parts, seven lis of sons 6 parts, Rhizoma Corydalis 5 parts, Radix Notoginseng 10 parts, Herba Schizonepetae 3 parts, Herba Erigerontis 8 parts, Rhizoma Corydalis 5 parts, Fructus Solani Lyrati 6 parts, Myrrha 3 parts, Radix Cyanotis vagae 10 parts, Pulvis Fumi Carbonisatus 3 parts, Herba Passiflorae Caeruleae 10 parts, Margarita powder 5 parts, Folium Isatidis 8 parts, 5 parts, Radix Glycyrrhizae.
Preparation method is made up of following steps: take raw material of Chinese medicine by above-mentioned weight portion, medicine except Margarita powder is put into 75% ethanol, ethanol did not have medical material 4cm, soak after 24 hours and take out, mash, dressing is made, with local anesthesia stapling at operative incision after mixing homogeneously with Margarita powder.
Below the present invention be described in detail, the above, be only the preferred embodiment of the present invention, when not limiting the scope of the present invention, namely allly does impartial change according to the application's scope and modify, all should still belong in covering scope of the present invention.
Claims (2)
1. for a local anesthetic for operative incision, it is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Flos Daturae 5 ~ 15 parts, Semen Hyoscyami 5 ~ 15 parts, seven lis of sons 3 ~ 6 parts, Rhizoma Corydalis 5 ~ 8 parts, Radix Notoginseng 5 ~ 10 parts, Herba Schizonepetae 3 ~ 6 parts, Herba Erigerontis 5 ~ 8 parts, Rhizoma Corydalis 5 ~ 10 parts, Fructus Solani Lyrati 3 ~ 6 parts, Myrrha 3 ~ 6 parts, Radix Cyanotis vagae 5 ~ 10 parts, Pulvis Fumi Carbonisatus 3 ~ 6 parts, Herba Passiflorae Caeruleae 5 ~ 10 parts, Margarita powder 5 ~ 8 parts, Folium Isatidis 5 ~ 8 parts, 5 ~ 8 parts, Radix Glycyrrhizae.
2. a kind of local anesthetic for operative incision as claimed in claim 1, is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Flos Daturae 12 parts, Semen Hyoscyami 10 parts, seven lis of sons 5 parts, Rhizoma Corydalis 7 parts, Radix Notoginseng 7 parts, Herba Schizonepetae 5 parts, Herba Erigerontis 6 parts, Rhizoma Corydalis 7 parts, Fructus Solani Lyrati 4 parts, Myrrha 5 parts, Radix Cyanotis vagae 8 parts, Pulvis Fumi Carbonisatus 5 parts, Herba Passiflorae Caeruleae 7 parts, Margarita powder 6 parts, Folium Isatidis 6 parts, 6 parts, Radix Glycyrrhizae.
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| CN201410757936.9A CN104435843A (en) | 2014-12-10 | 2014-12-10 | Local anesthetic for surgical incisions |
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| CN201410757936.9A CN104435843A (en) | 2014-12-10 | 2014-12-10 | Local anesthetic for surgical incisions |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105663821A (en) * | 2016-02-02 | 2016-06-15 | 钱浩 | Preparation method of anesthetic drug composition |
| CN105749331A (en) * | 2016-03-02 | 2016-07-13 | 山东睿鹰先锋制药有限公司 | Salvia sclarea wound dressing and preparation method thereof |
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| CN102908527A (en) * | 2012-11-12 | 2013-02-06 | 陈为宝 | Drug for post-perineotomy local anesthesia and analgesia |
| CN103536701A (en) * | 2012-07-10 | 2014-01-29 | 罗文礼 | Traditional Chinese medicinal composition with enhanced pain-relieving and calming effects and preparation method thereof |
| CN104043146A (en) * | 2014-06-25 | 2014-09-17 | 陈文灵 | Medical sponge for anesthesia department and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103536701A (en) * | 2012-07-10 | 2014-01-29 | 罗文礼 | Traditional Chinese medicinal composition with enhanced pain-relieving and calming effects and preparation method thereof |
| CN102908527A (en) * | 2012-11-12 | 2013-02-06 | 陈为宝 | Drug for post-perineotomy local anesthesia and analgesia |
| CN104043146A (en) * | 2014-06-25 | 2014-09-17 | 陈文灵 | Medical sponge for anesthesia department and preparation method thereof |
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| CN105663821A (en) * | 2016-02-02 | 2016-06-15 | 钱浩 | Preparation method of anesthetic drug composition |
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