CN104491166A - Traditional Chinese medicine composition with auxiliary anesthetic effect - Google Patents
Traditional Chinese medicine composition with auxiliary anesthetic effect Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention belongs to the technical field of herbal anaesthesia of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition with an auxiliary anesthetic effect. The traditional Chinese medicine composition is prepared from the following Chinese medicinal raw materials: 1-3 parts of datura stramonium, 1-3 parts of henbane, 5-10 parts of passion flowers, 3-5 parts of daphne giraldii, 5-8 parts of fourstamen stephania roots, 3-5 parts of radix scutellariae, 3-5 parts of Chinese herbaceous peony, 1-3 parts of olibanum, 1-3 parts of myrrh, 1-3 parts of caulis spatholobi, 1-3 parts of hematoxylon, 1-3 parts of ligusticum wallichii, 3-5 parts of dragon bone, 1-3 parts of nacre, 3-5 parts of oyster, 1-3 parts of platycladi seeds, 1-3 parts of tuber fleeceflower stem and 1-3 parts of liquorice. A decoction is prepared. Due to the efficacies of the traditional Chinese medicines for narcotizing, easing pain, relieving spasm and checking convulsions, combination of the medicinal materials with the effects of relaxing tendons, activating collaterals, and relaxing skeletal muscle, and optimization of the medicine proportion, psychentonia is reduced, and the effect of auxiliary anesthesia analgesia before an operation is achieved.
Description
Technical field
The invention belongs to Chinese medicine anaesthesia technology field, particularly a kind of Chinese medicine composition with Supplementary Anesthesia effect.
Background technology
The implication of anesthesia with medicine or additive method, entire patient or local is temporarily lost sensibility, and carries out operative treatment to reach painless object.Anesthesiology uses the rationale of relevant anesthesia, clinical knowledge and technology to eliminate corrective surgery pain, and guarantee patient safety is the science that operation creates good conditions.Now, anesthesiology to have become in clinical medicine a special independent educational project, mainly comprising the research of Clinical Anaesthesiology, emergency resuscitation medical science, Intensive care therapeutics, Diagnosis and Treatment of Pain and other relevant medical and mechanism thereof, is the comprehensive branch of learning of a research anesthesia, analgesia, emergency resuscitation and serious symptom medical science.Wherein clinical anesthesia is the major part of modern anaesthesia.But existing anesthesia often because the disposable concentration entering human body is high and produce larger side effect, has the limitation that medical treatment cost is high, curative effect is short simultaneously.
Chinese patent (CN102861153A) discloses a kind of local anesthetic, is made up of pure Chinese medicine, but infiltration is slow, zest is large, be unfavorable for that operative incision heals, and is not suitable for and anaesthetizes operative incision, and actual popularization has certain restriction.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition with Supplementary Anesthesia effect, by the effect that the analgesia of Chinese medicine, spasmolytic are only jerked, compatibility is with the medical material of relaxing muscles and tendons and activating QI and blood in the collateral, lax skeletal muscle, by optimizing compatibility of drugs ratio, reduce psychentonia, reach the analgesia of preoperative Supplementary Anesthesia, the effect of postoperative continuous narcosis analgesic.
The invention provides a kind of Chinese medicine composition with Supplementary Anesthesia effect, formulated by the raw material of Chinese medicine of following parts by weight: Flos Daturae 1 ~ 3 part, Semen Hyoscyami 1 ~ 3 part, Herba Passiflorae Caeruleae 5 ~ 10 parts, Daphne Giraldii Nitsche 3 ~ 5 parts, Radix Stephaniae Tetrandrae 5 ~ 8 parts, Radix Scutellariae 3 ~ 5 parts, Radix Paeoniae 3 ~ 5 parts, Olibanum 1 ~ 3 part, Myrrha 1 ~ 3 part, Caulis Spatholobi 1 ~ 3 part, Lignum Sappan 1 ~ 3 part, Rhizoma Chuanxiong 1 ~ 3 part, Os Draconis 3 ~ 5 parts, Concha Margaritifera 1 ~ 3 part, Concha Ostreae 3 ~ 5 parts, Semen Platycladi 1 ~ 3 part, Caulis Polygoni Multiflori 1 ~ 3 part, 1 ~ 3 part, Radix Glycyrrhizae.
More preferably formulated by the raw material of Chinese medicine of following parts by weight: Flos Daturae 2 parts, Semen Hyoscyami 2 parts, Herba Passiflorae Caeruleae 8 parts, Daphne Giraldii Nitsche 4 parts, Radix Stephaniae Tetrandrae 6 parts, Radix Scutellariae 4 parts, Radix Paeoniae 4 parts, Olibanum 2 parts, Myrrha 2 parts, Caulis Spatholobi 2 parts, Lignum Sappan 2 parts, Rhizoma Chuanxiong 2 parts, Os Draconis 4 parts, Concha Margaritifera 2 parts, Concha Ostreae 4 parts, Semen Platycladi 2 parts, Caulis Polygoni Multiflori 2 parts, 2 parts, Radix Glycyrrhizae.
Preparation method takes raw material of Chinese medicine according to formula and joins in container, adds water to cover powder and soak 25-30 minute, then add water and no powder 5-7 centimetre, decocts with high heat and uses slow fire boiling 30-40 minute again instead to seething with excitement, get filtrate; And then add water and do not have powder 5-7 centimetre, decoct with high heat and uses slow fire boiling 30-40 minute again instead to boiling, then remove slag and get filtrate, twice filtrate merges.
Pharmacology analysis:
Flos Daturae: acrid in the mouth, warm in nature, poisonous; Effect relieving cough and asthma, pain relieving is calm; Asthma and cough, coldness and pain in the epigastrium, rheumatic arthralgia, children's's intermittent infantile convulsion; Surgical anesthesia.Modern pharmacology proves, it has certain analgesic activity, and can strengthen the analgesic activity of dolantin, and the threshold of pain that antagonism norepinephrine intracerebroventricular injection causes reduces and the weakening of dolantin analgesic activity.
Semen Hyoscyami: warm in nature, bitter in the mouth is pungent, enters the heart, stomach, liver three warp, poisonous, has the effect of determining epilepsy, pain relieving.Modern pharmacological research shows, Semen Hyoscyami contains alkaloid, is mainly hyoscyamine, atropine and scopolamine, and reasonable volume has obvious relexation to smooth muscle, and energy elevated intraocular pressure and paralysis accommodation, also can be used for the poisoning severe arrhythmia caused of antimony agent.
Herba Passiflorae Caeruleae: warm in nature, bitter in the mouth is nontoxic.For neuralgia, insomnia, the disease such as menstrual pain and dysentery, has anesthesia and sedation.
Daphne Giraldii Nitsche: sweet, temperature.Effect pain relieving, loose blood, enriches blood, has narcoticness.Herb is used as medicine, energy relieving rigidity of muscles and knitting bone, reducing swelling and alleviating pain; Root effect relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain; For rheumatic arthralgia, lumbago; Traumatic injury is controlled in external, fracture.Flower effect dispelling pathogenic wind for improving eyesight; For conjunctival congestion and pain of eye, nyctalopia.
Radix Stephaniae Tetrandrae: row water, rushes down damp-heat in lower-JIAO.Harness the river swollen tympanites, hygropyretic beriberi, brothers' spasm and pain, tinea scabies swells.Modern pharmacology proves tetrandrine, has hypotensive effect.
Radix Scutellariae: bitter in the mouth, cold in nature, enters the heart, lung, gallbladder, large intestine channel; There are heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive; Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.Modern pharmacology proves, Radix Scutellariae has the effects such as antibacterial action, antifungic action, antivirus action and antiinflammatory antiallergic action, and does not develop immunity to drugs.
Radix Paeoniae: Radix Paeoniae contains the multi-medicament such as peoniflorin and paeoniflorin composition, has the effect of blood vessel dilating, blood pressure lowering analgesia, heat clearing away spasmolytic, has higher medical value.
Olibanum: acrid in the mouth, heat, micro-poison; Enter the heart, liver, spleen channel; Function regulating qi and activating blood, analgesic therapy, chases after poison.Cure mainly coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Myrrha: bitter, pungent is flat; Enter liver, spleen, the heart, kidney channel.Function hair growing, speckle dispelling disappears trace, and softening the hard mass is except tumor, and except tinea more wound, teeth consolidating is good for gum, removing toxic substances etc.; Cure mainly alopecia capillary, black spot bruise, verruca plana, various eczema, gingiva is rotten to the corn, and poisonous insect stings wound etc.
Caulis Spatholobi: the dry stomach of invigorating middle warmer, blood stasis removing blood, tissue regeneration promoting blood, fluent passages through which vital energy circulates, controls summer filthy infection, wind arthralgia due to stagnation of blood disease.
Lignum Sappan: sweet, salty, Xin Liang; GUIXIN, liver, stomach, spleen channel.Function blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain; Cure mainly married woman's amenorrhea due to stagnation of blood, dysmenorrhea, postpartum stagnation cardiac and abdominal pain, puerperal blood faints, carbuncle, traumatic injury, tetanus.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For pacifying nerve, positive wind syndrome of head headache, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Os Draconis: property sweet-puckery flavor are flat; Enter the heart, liver, kidney, large intestine channel.Function tranquillization with heavy prescription, tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing; Cure mainly infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, and seminal emission stranguria with turbid discharge, tell nosebleed and have blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time.
Concha Margaritifera: salty, cold; Return liver, heart channel.Effect suppressing the hyperactive liver, YANG hyperactivity suppressing, arresting convulsion, hemostasis; Cure mainly dizziness, tinnitus, cardiopalmus, insomnia, demented, infantile convulsion, spits blood, epistaxis, metrorrhagia.
Concha Ostreae: tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving, restrains astringent or styptic treatment for spontaneous sweating, for insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, note of the ancient Chinese abdominal mass mass in the abdomen, spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache pantothenic acid.Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating, for spontaneous sweating, and seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.
Semen Platycladi: sweet is flat; GUIXIN, kidney, large intestine channel.Function tranquilizing by nourishing the heart, loosening bowel to relieve constipation.For restlessness of asrhenia type and insomnia, severe palpitation, the diseases such as dryness of the intestine constipation.
Caulis Polygoni Multiflori: sweet micro-hardship is flat; Enter the heart, spleen, kidney, Liver Channel.Control insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies.
Radix Glycyrrhizae: sweet in the mouth, property is put down; Enter spleen, stomach, lung meridian; Function invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, clear throat, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Chinese medicine of the present invention, the effect of only being jerked by the analgesia of Chinese medicine, spasmolytic, compatibility, with the medical material of relaxing muscles and tendons and activating QI and blood in the collateral, lax skeletal muscle, by optimizing compatibility of drugs ratio, reduces psychentonia, reaches the analgesia of preoperative Supplementary Anesthesia, the effect of postoperative continuous narcosis analgesic.
Outcome measure:
Effective: after taking medicine, in 15min, pain obviously weakens, injecting anesthetic medicine more than 50% in art can be reduced, have no adverse reaction and malaise symptoms;
Effective: after taking medicine, in 30min, pain obviously weakens, injecting anesthetic medicine more than 30% in art can be reduced, have no adverse reaction and malaise symptoms;
Invalid: to keenly feel in use procedure and do not alleviate, patients' neural's consciousness is under some influence, and has ill symptoms to occur.
Therapeutic outcome: use to 227 postoperative patients, operation consent is taken medicine half an hour, effective 144 examples, account for 63.4%, and effective 82 examples, account for 36.1%, and invalid 1 example, accounts for 0.5%.
Attached several routine case is described further:
Case 1: prunus mume (sieb.) sieb.et zucc. so-and-so, man, 12 years old, before carrying out Appendectomy, because of poor to the toleration of Western medicine anaesthetic, there is larger side effect, then give herbal anesthetic Supplementary Anesthesia of the present invention, reduce the dosage of anesthetics half, without pain after 15min, continuous action in operation process, without the need to administration again.
Case 2: Cao, female, 56 years old, gives Chinese medicine Supplementary Anesthesia of the present invention agent, carries out Supplementary Anesthesia before carrying out mammary cancer surgery, reduces the dosage of anesthetics 30%, and without pain after 20min, continuous action in operation process, without the need to administration again.
Detailed description of the invention
Embodiment 1:
There is a Chinese medicine composition for Supplementary Anesthesia effect, formulated by the raw material of Chinese medicine of following parts by weight: Flos Daturae 2 parts, Semen Hyoscyami 2 parts, Herba Passiflorae Caeruleae 8 parts, Daphne Giraldii Nitsche 4 parts, Radix Stephaniae Tetrandrae 6 parts, Radix Scutellariae 4 parts, Radix Paeoniae 4 parts, Olibanum 2 parts, Myrrha 2 parts, Caulis Spatholobi 2 parts, Lignum Sappan 2 parts, Rhizoma Chuanxiong 2 parts, Os Draconis 4 parts, Concha Margaritifera 2 parts, Concha Ostreae 4 parts, Semen Platycladi 2 parts, Caulis Polygoni Multiflori 2 parts, 2 parts, Radix Glycyrrhizae.
Preparation method takes raw material of Chinese medicine according to formula and joins in container, adds water to cover powder and soak 30 minutes, then add water and do not have powder 6 centimetres, decocts with high heat and uses slow fire boiling again instead 35 minutes to boiling, get filtrate; And then add water and do not have powder 6 centimetres, decoct with high heat and uses slow fire boiling again instead 35 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
Embodiment 2:
There is a Chinese medicine composition for Supplementary Anesthesia effect, formulated by the raw material of Chinese medicine of following parts by weight: Flos Daturae 1 part, Semen Hyoscyami 3 parts, Herba Passiflorae Caeruleae 5 parts, Daphne Giraldii Nitsche 5 parts, Radix Stephaniae Tetrandrae 5 parts, Radix Scutellariae 5 parts, Radix Paeoniae 3 parts, Olibanum 3 parts, Myrrha 1 part, Caulis Spatholobi 3 parts, Lignum Sappan 1 part, Rhizoma Chuanxiong 3 parts, Os Draconis 3 parts, Concha Margaritifera 3 parts, Concha Ostreae 3 parts, Semen Platycladi 3 parts, Caulis Polygoni Multiflori 1 part, 3 parts, Radix Glycyrrhizae.
Preparation method takes raw material of Chinese medicine according to formula and joins in container, adds water to cover powder and soak 25 minutes, then add water and do not have powder 5 centimetres, decocts with high heat and uses slow fire boiling again instead 30 minutes to boiling, get filtrate; And then add water and do not have powder 5 centimetres, decoct with high heat and uses slow fire boiling again instead 30 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
Embodiment 3:
There is a Chinese medicine composition for Supplementary Anesthesia effect, formulated by the raw material of Chinese medicine of following parts by weight: Flos Daturae 3 parts, Semen Hyoscyami 1 part, Herba Passiflorae Caeruleae 10 parts, Daphne Giraldii Nitsche 3 parts, Radix Stephaniae Tetrandrae 8 parts, Radix Scutellariae 3 parts, Radix Paeoniae 5 parts, Olibanum 1 part, Myrrha 3 parts, Caulis Spatholobi 1 part, Lignum Sappan 3 parts, Rhizoma Chuanxiong 1 part, Os Draconis 5 parts, Concha Margaritifera 1 part, Concha Ostreae 5 parts, Semen Platycladi 1 part, Caulis Polygoni Multiflori 3 parts, 1 part, Radix Glycyrrhizae.
Preparation method takes raw material of Chinese medicine according to formula and joins in container, adds water to cover powder and soak 30 minutes, then add water and do not have powder 7 centimetres, decocts with high heat and uses slow fire boiling again instead 40 minutes to boiling, get filtrate; And then add water and do not have powder 7 centimetres, decoct with high heat and uses slow fire boiling again instead 40 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
Below the present invention be described in detail, the above, be only the preferred embodiment of the present invention, when not limiting the scope of the present invention, namely allly does impartial change according to the application's scope and modify, all should still belong in covering scope of the present invention.
Claims (2)
1. there is a Chinese medicine composition for Supplementary Anesthesia effect, it is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Flos Daturae 1 ~ 3 part, Semen Hyoscyami 1 ~ 3 part, Herba Passiflorae Caeruleae 5 ~ 10 parts, Daphne Giraldii Nitsche 3 ~ 5 parts, Radix Stephaniae Tetrandrae 5 ~ 8 parts, Radix Scutellariae 3 ~ 5 parts, Radix Paeoniae 3 ~ 5 parts, Olibanum 1 ~ 3 part, Myrrha 1 ~ 3 part, Caulis Spatholobi 1 ~ 3 part, Lignum Sappan 1 ~ 3 part, Rhizoma Chuanxiong 1 ~ 3 part, Os Draconis 3 ~ 5 parts, Concha Margaritifera 1 ~ 3 part, Concha Ostreae 3 ~ 5 parts, Semen Platycladi 1 ~ 3 part, Caulis Polygoni Multiflori 1 ~ 3 part, 1 ~ 3 part, Radix Glycyrrhizae.
2. a kind of Chinese medicine composition with Supplementary Anesthesia effect as claimed in claim 1, is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Flos Daturae 2 parts, Semen Hyoscyami 2 parts, Herba Passiflorae Caeruleae 8 parts, Daphne Giraldii Nitsche 4 parts, Radix Stephaniae Tetrandrae 6 parts, Radix Scutellariae 4 parts, Radix Paeoniae 4 parts, Olibanum 2 parts, Myrrha 2 parts, Caulis Spatholobi 2 parts, Lignum Sappan 2 parts, Rhizoma Chuanxiong 2 parts, Os Draconis 4 parts, Concha Margaritifera 2 parts, Concha Ostreae 4 parts, Semen Platycladi 2 parts, Caulis Polygoni Multiflori 2 parts, 2 parts, Radix Glycyrrhizae.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105596584A (en) * | 2015-09-21 | 2016-05-25 | 钱培培 | Traditional Chinese medicine preparation special for local anesthesia and preparation method thereof |
| CN105663431A (en) * | 2016-02-24 | 2016-06-15 | 林立朋 | Medicine composition used for clinical anesthesia and preparation method thereof |
| CN106581534A (en) * | 2016-12-30 | 2017-04-26 | 陈海燕 | Medicine composition used for toothache surgery anesthesia and preparation method of medicine composition |
| CN108272904A (en) * | 2018-04-21 | 2018-07-13 | 王晓璐 | The portrait or photograph of the deceased rings low anesthesia plant extracts and its manufacturing method after a kind of |
-
2014
- 2014-12-30 CN CN201410844059.9A patent/CN104491166A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105596584A (en) * | 2015-09-21 | 2016-05-25 | 钱培培 | Traditional Chinese medicine preparation special for local anesthesia and preparation method thereof |
| CN105663431A (en) * | 2016-02-24 | 2016-06-15 | 林立朋 | Medicine composition used for clinical anesthesia and preparation method thereof |
| CN106581534A (en) * | 2016-12-30 | 2017-04-26 | 陈海燕 | Medicine composition used for toothache surgery anesthesia and preparation method of medicine composition |
| CN108272904A (en) * | 2018-04-21 | 2018-07-13 | 王晓璐 | The portrait or photograph of the deceased rings low anesthesia plant extracts and its manufacturing method after a kind of |
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