CN103463293B

CN103463293B - Method for preparing traditional Chinese medicine composite for treating lumbar spinal stenosis

Info

Publication number: CN103463293B
Application number: CN201310457499.4A
Authority: CN
Inventors: 叶红
Original assignee: 叶红
Current assignee: Lin Lina
Priority date: 2013-09-30
Filing date: 2013-09-30
Publication date: 2015-02-04
Anticipated expiration: 2033-09-30
Also published as: CN103463293A

Abstract

The invention provides a method for preparing a traditional Chinese medicine composite for treating lumbar spinal stenosis. The method comprises the steps that raw medicine is dipped in water; the water adding amount is 2.5-3 times as much as the total weight of the raw medicine; after the medicine is dipped for one hour, the medicine is boiled for 50min-60min by slow fire; liquid medicine is filtered and medicine dregs can be obtained; water is added to the medicine dregs again; the water adding amount is 1-1.5 times of the total weight of the raw medicine; the medicine is boiled for 50min-60min by slow fire; liquid medicine is filtered; the liquid medicine obtained through the two times of filtration is combined, concentrated and dried; after the liquid medicine is dried to concentrated unguent with the moisture smaller than 30%, the unguent is dissolved in honey with the weight being 1.5-2 times as much as the total weight of the raw medicine; the raw medicine is composed of, by weight, 18-22 parts of cinnamon, 13-15 parts of moutan bark, 1-2 parts of asarum, 5-8 parts of dried rehmannia root, 8-10 parts of panax notoginseng, 10-12 parts of loranthus parasiticus and 1-1.5 parts of aconite.

Description

A kind of preparation method for the treatment of the Chinese medicine composition of lumbar spinal stenosis

Technical field

The present invention relates to the technical field of Chinese medicine composition, a kind of preparation method being used for the treatment of the Chinese medicine composition of lumbar spinal stenosis is particularly provided.

Background technology

Lumbar spinal stenosis refer to Lumbar Vertebral Canal, the isometrical line of lateral crypt and neural duct caused the congenital or day after tomorrow reduce cause horse hair or root compression and produce chronic lumbago and skelalgia, intermittent claudication is the syndrome of cardinal symptom, it has had a strong impact on the life of patient, work, study and work.Particularly along with the arriving gradually of China's aging society, there is lumbar spinal stenosis due to the degenerative change of lumbar vertebra soft tissue in increasing old people patient, and gerontal patient due to the time of morbidity long, state of an illness weight, it is very large to treat difficulty.

The more commonly operative treatment of current treatment lumbar spinal stenosis, the object of operative treatment alleviates lower limb indication, but for alleviating lumbago symptom effect and not obvious.Further, operation object is only mitigation symptoms instead of healing, and it can't make to have occurred the intervertebral disc of degenerative change and Minor articulus recovers normal, can not the naturally-aged process of vertebra degenerative change that cause such as age of tissue.Meanwhile, the Hazard ratio of operative treatment is comparatively large, may leave more sequela, or even causes injury, disables.

Except operative treatment, conservative medication is also the treatment means of more employing.Drug therapy is again with Western medicine and two kinds, Chinese medicine, and Western medicine is main or the effect of analgesic relief, remains index and does not effect a permanent cure.The such as YAOTONGNING etc. that Chinese medicine is relatively more conventional at present, formula is complicated, and effect is also desirable not enough.

Therefore, develop a kind of formula relatively simple, therapeutic effect obviously and can the lumbar spinal stenosis Chinese medicine composition for the treatment of both the principal and secondary aspects of a disease, be the important directions in TCM investigation field.

Summary of the invention

Namely object of the present invention is to provide a kind of novel formula relatively simple, and therapeutic effect obviously and can the lumbar spinal stenosis Chinese medicine composition for the treatment of both the principal and secondary aspects of a disease.

Lumbar spinal stenosis Chinese medicine composition described in the present invention is made up of following compositions: with parts by weight, Cortex cinnamomi japonici (Ramulus Cinnamomi) 18-22 part, Cortex Moutan 13-15 part, Herba Asari 1-2 part, Radix Rehmanniae 5-8 part, Radix Notoginseng 8-10 part, Herba Taxilli 10-12 part, Aconitum carmichjaelii Debx. 1-1.5 part.

Wherein, each component preferably, 20 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi), Cortex Moutan 10 parts, Herba Asari 1 part, Radix Rehmanniae 6 parts, Radix Notoginseng 8 parts, Herba Taxilli 10 parts, Aconitum carmichjaelii Debx. 1.2 parts.

In medication process, for ease of taking, Chinese medicine composition in the present invention can be prepared as follows, specifically take each crude drug by said components proportioning, then crude drug is soaked, amount of water with the 2.5-3 of all crude drug gross weights doubly, soak time one hour, then slow fire decocting 50-60min, leach medicinal liquid, obtain medicinal residues, then medicinal residues are added water again, amount of water is 1-1.5 times of crude drug gross weight, slow fire decocting 50-60min, leach medicinal liquid, twice is leached medicinal liquid to merge, carry out concentrated oven dry, dry as after moisture is less than the concentrated ointment of 30%, dissolved in crude drug gross weight 1.5-2 Mel doubly.

Mechanism of making up a prescription of the present invention: China's Traditional Chinese medical theory is thought, the main cause of lumbar spinal stenosis is due to qi depression to blood stasis, wind-cold damp pathogen, suffer from a deficiency of the kidney caused by.For above-mentioned symptom, present invention employs these common, cheap Chinese crude drugs of Cortex cinnamomi japonici (Ramulus Cinnamomi), Cortex Moutan, Herba Asari, Radix Rehmanniae, Radix Notoginseng, Herba Taxilli and Aconitum carmichjaelii Debx..

Concrete, the Cortex cinnamomi japonici (Ramulus Cinnamomi) in formula belongs to India section, property of medicine temperature, and taste is micro-sweet, pungent, there is cold-dispelling pain-relieving, effect that warming the spleen stomach, warm Liver and kidney, vomiting are had loose bowels, clinically there is analgesia, spasmolysis is remarkable.Being usually used in the fear of cold for administering insufficiency of kidney-YANG, cold extremities, chills and pain of the waist and kness clinically, also can be used for the dyspnea due to deficiency of failure of the kidney in receiving QI, QI rising in reverse order.

The Cortex Moutan property of medicine is slightly cold, bitter in the mouth, pungent, and GUIXIN, liver, kidney channel, have effect of clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, cures mainly heat and enter nutrient blood, maculae caused by violent heat pathogen, night fever abating at dawn, hematemesis and epistaxis, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus and fall to flutter the pain of injury.Meanwhile, modern pharmacological research shows, Cortex Moutan has antiallergic, antiinflammatory, antitumor, calmness, analgesia, blood pressure lowering, hypnosis, immunomodulating and antiendotoxin and the effect such as antipyretic.

Herba Asari is aristolochiaceae plant Herba Asari or magnificent thin dry herb, property of medicine temperature, taste great Xin; GUIXIN, lung, kidney channel, have expelling wind and cold, understand things pain-stopping, the effect of warming the lung to resolve fluid-retention.

Radix Rehmanniae is the dried root of scrophulariaceae rehmannia glutinosa plant, and its property of medicine is cool, sweet in the mouth, hardship, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, effect of YIN nourishing and the production of body fluid promoting, nutrient blood is entered, maculae caused by violent heat pathogen, hematemesis and epistaxis for heat, consumption of YIN caused by febrile disease, crimson tongue excessive thirst, constipation is hindered in Tianjin, fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst.

Radix Notoginseng is the root of araliaceae ginseng plant Radix Notoginseng, property of medicine temperature, sweet and slightly bitter taste, return liver, stomach, the heart, large intestine channel, nontoxic, there is effect of dissipating blood stasis hemostasis, subduing swelling and relieving pain, be mainly used in haematemesis, hemoptysis, have blood in stool, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling etc.

Herba Taxilli is the band leaf branch stem of Loranthaceae evergreen dwarf shrub plant Herba Taxilli, mild in medicine property, and taste is dry, bitter, return liver, kidney channel, nontoxic, there is effect of invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, be mainly used in that limbs are hemiplegia, rheumatic arthralgia, soreness of the waist and knees, muscles and bones are unable etc.

Aconitum carmichjaelii Debx. is the parent root of Ranunculaceae aconitum plant Aconitum carmichjaelii Debx., property of medicine heat, acrid in the mouth, hardship, large poison, GUIXIN, liver,kidney,spleen warp, have expelling wind and removing dampness, effect of antalgic, is mainly used in anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic etc.

In we, Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Taxilli, Herba Asari, Aconitum carmichjaelii Debx. are the genus of warm the kidney invigorating, can play the effect significantly making up yang deficiency deficiency of the kidney, and Cortex Moutan then can play the effectiveness dispelling monarch fire, share to avoid the hyperfunction of the kidney yang caused by temperature compensation with Radix Rehmanniae; Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Notoginseng and Cortex Moutan all have effect of promoting the circulation of blood blood stasis dispelling, and Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Asari, Radix Notoginseng and Aconitum carmichjaelii Debx. are also by the effectiveness that can play significant warming the interior pain relieving simultaneously.Moreover temperature in we, cold and use, with Wen Weizhu, suit the medicine to the illness well in the symptom of caused by liver and kidney deficiency, congestion retardance.Adopt Chinese herbal medicine that is nontoxic or micro-poison in we, the Herba Asari larger for toxicity and Aconitum carmichjaelii Debx., strict its consumption of control, so that its effect can be played on a small quantity for use more simultaneously.

Can say, Chinese medicine composition of the present invention rationally, forbid, each component coordinative role, has the curative effect of significant wind-damp dispelling, invigorating the liver and kidney, dredge the meridian passage, strengthening the tendons and bones, promoting the circulation of blood blood stasis dispelling by compatibility.

Detailed description of the invention

Below by specific embodiment, the curative effect of Chinese medicine composition of the present invention for lumbar spinal stenosis is described, adopts marking system as diagnosis and treatment standard, specifically see table 1.

The formula of Chinese medicine composition used is 20 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi), Cortex Moutan 10 parts, Herba Asari 1 part, Radix Rehmanniae 6 parts, Radix Notoginseng 8 parts, Herba Taxilli 10 parts, Aconitum carmichjaelii Debx. 1.2 parts, said components proportioning is taken each crude drug, then crude drug is soaked, amount of water is with 3 times of all crude drug gross weights, soak time one hour, then slow fire decocting 60min, leach medicinal liquid, obtain medicinal residues, then medicinal residues are added water again, amount of water is 1.5 times of crude drug gross weight, slow fire decocting 50min, leach medicinal liquid, twice is leached medicinal liquid to merge, carry out concentrated oven dry, dry as after moisture is less than the concentrated ointment of 30%, dissolved in the Mel of crude drug gross weight 1.5 times.Dosage is that the consumption of a day is 2g in Cortex cinnamomi japonici (Ramulus Cinnamomi) in crude drug, and administration time continues 6 months.

Medication for case be and be diagnosed as lumbar spinal stenosis and without the sufferer of obvious curative effects more than taking YAOTONGNING JIAONANG half a year, wherein male 5 example, women 3 example, the age from 55-80 year, average 72 years old.

Table 2 is the scale before and after sufferer medication, can think, when scoring improvement more than 10 points (most symptom be improved significantly) for effective, scoring improvement more than 6 points (most of partial symptoms improves) for effectively, scoring improvement more than 2 points for (having symptom to improve) for minor effect, improvement of marking be less than 2 points be invalid, visible, 8 routine sufferers no matter symptom weight, all after continuing to take Chinese medicine of the present invention half a year, obtain curative effect, wherein effective have 1 example, be effectively 4 examples, all the other 3 examples also all obtain certain curative effect.Visible Chinese medicine of the present invention has good therapeutic effect for lumbar spinal stenosis.

Claims

1. treat the preparation method of the Chinese medicine composition of lumbar spinal stenosis for one kind, it is characterized in that: first crude drug is soaked, amount of water with the 2.5-3 of all crude drug gross weights doubly, soak time one hour, then slow fire decocting 50-60min, leach medicinal liquid, obtain medicinal residues, then again added water by medicinal residues, amount of water is 1-1.5 times of crude drug gross weight, slow fire decocting 50-60min, leach medicinal liquid, twice is leached medicinal liquid and merge, carry out concentrated oven dry, dry as after moisture is less than the concentrated ointment of 30%, dissolved in the Mel of crude drug gross weight 1.5-2 times;

Wherein, described crude drug is made up of following compositions: with parts by weight, Cortex cinnamomi japonici (Ramulus Cinnamomi) 18-22 part, Cortex Moutan 13-15 part, Herba Asari 1-2 part, Radix Rehmanniae 5-8 part, Radix Notoginseng 8-10 part, Herba Taxilli 10-12 part, Aconitum carmichjaelii Debx. 1-1.5 part.