CN102846870A - External anti-inflammatory drug from the Miao nationality and production process thereof - Google Patents

External anti-inflammatory drug from the Miao nationality and production process thereof Download PDF

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CN102846870A
CN102846870A CN2012103040800A CN201210304080A CN102846870A CN 102846870 A CN102846870 A CN 102846870A CN 2012103040800 A CN2012103040800 A CN 2012103040800A CN 201210304080 A CN201210304080 A CN 201210304080A CN 102846870 A CN102846870 A CN 102846870A
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herba
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CN102846870B (en
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袁涛忠
何兆辉
黄玉珍
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Abstract

The invention relates to an external anti-inflammatory drug prepared from the raw materials of medicinal plants used by the Miao nationality. The external anti-inflammatory drug comprises the following components: 2-4 parts of honeysuckle, 1-3 parts of rhizoma cibotii, 1-3 parts of solidago decurrens, 1-2 parts of woad, 2-4 parts of fringed iris, 1-3 parts of dandelion and 2-3 parts of chrysanthemum. The external anti-inflammatory drug is an integrity of anti-inflammatory agent, cleaning agent, bath agent and antipruritic agent. The indications and usages of the external anti-inflammatory drug are more than those of the currently widely used drugs and preparations, such as Daktarin cream, calamine and menthol lotion, Jieeryin, Fu Yanjie, external zijin troches, Chuanbai anti-itching lotion, Shibiling anti-itching anti-inflammatory lotion and Sanwei heat-clearing anti-itching lotion. The preparation prepared from the formula contains no chemicals, and is a pure natural medicinal plant preparation; besides, the external anti-inflammatory drug has no toxic or side effect, or irritation on skin and mucosa of adult and infant, and is an essential household medicine.

Description

Miao ethnic group's externally applied anti-inflammation medicine and preparation technology
Technical field
The present invention relates to Miao ethnic group's medicinal plants is the externally applied anti-inflammation medicine that raw material is made.
Background technology
Women's gynecological inflammation, infantile eczema, baby's diaper dermatitis, child because of mosquito bite the scytitis that causes etc. be clinical common inflammation, also be the commonly encountered diseases in the family health care.A lot of family, medicine enterprises of curing are in safe, the evident in efficacy remedy,topical of effort innovation for these inflammation treatments.
At present, though these medicines, the preparation of a multitude of names are arranged, all exist the not ideal enough or function singleness limitation of curative effect.So clinically demand urgently developing a kind of nontoxic, non-stimulated to human body apparatus urogenitalis skin, mucosa, infant skin, mucosa, the broad-spectrum disease resistance pathogenic microorganism, the antiinflammation that do not contain chemical addition agent are strong, applied range, externally applied anti-inflammation medicine evident in efficacy.
Antibiotic medicine of the present invention, that the inventor is under the prerequisite of adhering to Seedling medicine reality principle, according to spontaneous medical experience, use Seedling medicinal knowledge and modern medicine and gain knowledge Miao ethnic group's Category of the diseases such as numerous different topical therapeutic " vulvitis; vaginitis; urethritis; infant eczema, diaper rash (baby's diaper dermatitis); miliaria alba; insect dermatitis " of Miao ethnic group's prolonged application among the people is analysed in depth after the research again prescription, the breen made from the modern medicines preparation technique, clear and bright, external preparation that special aroma, stable in properties are arranged.
Summary of the invention
Main purpose of the present invention provides a kind of pure natural, to human body apparatus urogenitalis skin, mucosa, infant skin, mucosa are nontoxic, non-stimulated, do not contain strong externally applied anti-inflammation medicine and the preparation technology of broad-spectrum disease resistance pathogenic microorganism, antiinflammation of chemical addition agent.
For achieving the above object, the technical solution adopted in the present invention is: a kind of externally applied anti-inflammation medicine is comprised of the component of following weight ratio:
Radix Ophiopogonis (Latin name: Lonicera japonica Thunb; Miao: the nearly sound word of Bangx ghab dlad(Chinese: list Ga She)) 2~4 parts;
Rhizoma Cibotii (Latin name: Woodwardia japonica(L.F.) Smith; Miao: good under the Ghaib xad jad(lid)) 1~3 part;
Herba Solidaginis (Latin name: Solidago decurrens Lour.; Miao: the good flat powder of Jab biex fiex()) 1~3 part;
Isatis indigotica Fort. (Latin name: Isatis indigotica Fort.; Miao: your nest of Nix vob()) 1~2 part;
Herba Iridis japonicae (Latin name: Iris japonica Thunb; Miao: Vob dak dlangd(nest reaches still)) 2~4 parts;
Herba Taraxaci (Latin name: Taraxacum mongolicum Hand.-Mazz.; Miao: Vob eb wel(nest is oh recessed)) 1~3 part;
Herba Dendranthematis indici (Latin name: Chrysanthemum indicum L.; Miao: Vob senb lot(nest item is glutinous)) 2~3 parts.
Medicine of the present invention is made as spray or washing liquid usually, is convenient to hydro-peening or is watered take a shower or cleaning.Medicine of the present invention will realize that goal of the invention only needs component as above, but also can add other fragrant extract etc. in the component of the present invention, additional other function or with the composite use of other preparation.
Further preferred: 3 parts of described Radix Ophiopogoniss, 2 parts of Rhizoma Cibotii, 2 parts of Herba Solidaginiss, 1 part of Isatis indigotica Fort., 3 parts of Herba Iridis japonicae, 2 parts of Herba Taraxacis, 3 parts in Herba Dendranthematis indici.
Further preferred: 3 parts of described Radix Ophiopogoniss, 3 parts of Rhizoma Cibotii, 3 parts of Herba Solidaginiss, 1 part of Isatis indigotica Fort., 4 parts of Herba Iridis japonicae, 2 parts of Herba Taraxacis, 2 parts in Herba Dendranthematis indici.
Further preferred: 4 parts of described Radix Ophiopogoniss, 3 parts of Rhizoma Cibotii, 3 parts of Herba Solidaginiss, 2 parts of Isatis indigotica Fort., 4 parts of Herba Iridis japonicae, 3 parts of Herba Taraxacis, 3 parts in Herba Dendranthematis indici.
Accordingly, the preparation technology of externally applied anti-inflammation medicine of the present invention, step comprises:
After this prescription pulverizing medicinal materials with the airtight dipping of 95% ethanol, with medicated powder even moistening degree of being expanded to fully;
Medicated powder behind the dipping is even, degree of tightness is as one man packed percolator into, adds 95% ethanol, and addition is 2 times of this prescription medical material weight, airtight dipping 48h; Described degree of tightness unanimously is exactly as far as possible so that the medicated powder degree of tightness is consistent, and for example evenly loose packing into need not to compress.
Flow out 2mL speed percolation with medical material 1000g per minute, synchronized adding 60% ethanol, addition is 2 times of this prescription medical material weight; Collection is filtered and is got percolate (1) when liquid measure reaches 3.5 times of this prescription medical material weight;
Continuous percolation, synchronized adding purified water, addition are 2 times of this prescription medical material weight; Collection is filtered and is got percolate (2) when liquid measure reaches 2 times of this prescription medical material weight;
Continuous percolation ends to the liquid of filtering is colourless, obtains the continuous liquid of filtering;
Percolate (1), (2) get concentrated solution behind Recycled ethanol; The continuous liquid of filtering that adds this prescription medical material weight 1/2nd weight in the concentrated solution, leaves standstill, considered at mixing, add again the continuous liquid of filtering quantitative finished product.
Further, described Recycled ethanol adopts reduced pressure distillation process to carry out.
Further, pulverizing medicinal materials is to the medium powder fineness." the medium powder fineness of Chinese pharmacopoeia regulation namely.
Further, during the airtight dipping medical material of described 95% ethanol, the liquid-solid mass ratio of 95% ethanol and medical material powder is 2:1, airtight placement 2h.
Further, described purified product 1ml is equivalent to crude drug 1g.
The product of making by this technique shows this extraction scheme craft science, reasonable, novel after using, and the quality of the pharmaceutical preparations meets every regulation requirement, and is remarkably productive, without toxicity, is convenient to produce and use.
In view of the chemical constituent of Miao Ethnomedicine compound recipe very complicated, and the chemical constituent that the physical and chemical reaction that occurs in processing and making process might cause having disappears or the generation novel compound, therefore, finding extraction to this Miao Ethnomedicine compound recipe to make its elaboration products (compound recipe) become " natural combination chemical combination storehouse " and produce the effect of " multiple target effect ", is the basic ideas of this prescription Miao Ethnomedicine separation and Extraction.From these basic ideas, the inventor carries out the preparation process design according to the character of this prescription Miao ethnic group medicinal plants and this composing prescription preparation application target, application approach.Purpose is this prescription Miao ethnic group medicinal plants processing of crude drugs to be made application safety, definite effect, the stable in properties, controlled of the certain specification that is suitable for application form, and economic goods.
This preparation process is deferred to the separating technology design principle of " safety, effectively, stable, homogeneous, economy ", according to the dissolution properties of various compositions in solvent in each medical material in this Miao Ethnomedicine prescription, select ethanol to make solvent, according to " percolation " (Chinese name republic pharmacopeia 2010 editions one one), adopt accurate, easy, representative, quantifiable comprehensive evaluation index, this Miao Ethnomedicine prescription is carried out compound recipe extract.In the extraction process, pay attention to solvent, the conditions such as the concentration of solvent, time are on extracting the impact that separates, and have designed with opposed polarity solvent, variable concentrations solvent, at normal temperatures in the same container, extract the extraction scheme of this prescription medicinal plants composition.
Miao ethnic group's medicinal plants that forms this prescription is loaded " Chinese Plants will " or as documents such as " Plants From Guizhou will " all.What wherein be written into the Pharmacopoeia of the People's Republic of China has Radix Ophiopogonis, Herba Dendranthematis indici, Herba Solidaginis, Isatis indigotica Fort., a Herba Taraxaci; Rhizoma Cibotii is written into the 93rd page of " Guizhou Province's Chinese crude drug quality standard " version in 1988; Herba Iridis japonicae is written into the 495th page of " Plants From Guizhou will " the 6th volume.
Useful technique effect of the present invention:
This prescription is completely different with the prescription of the preparation of existing treatment " vaginitis, urethritis, infant eczema, diaper disease, erythema (red hip), miliaria alba, insect dermatitis ".With regard to application site, function and the usage of the single medicinal plants of this prescription, all the application with contained these medicinal plants of state-promulgated pharmacopoeia and medicine monograph is very different.
The bioactive substance of the contained flavonoid of this composing prescription preparation, terpenoid, alkaloids, sterols, volatile oil, glucide class, organic acid etc. all comes from natural plants, they or directly act on body surface, mucosa, or through skin, mucosa absorption, given play to biological effect.The indigo alkaloid such as indirubin in the preparation, the Rhizoma Iridis Tectori isoflavone, phenolic acids, glycoside, volatile oil, sterols, Kaempferol-rutinoside, chlorogenic acid, isochlorogenic acid, taraxasterol, choline etc. has resisting pathogenic microbes, infection, antiinflammatory, suppress increasing of capillary of skin permeability, suppress the generation of prostaglandin E, analgesia, rheumatism, anastalsis, has the inhibition connective tissue proliferation, it is synthetic to suppress glue unit, anti peroxidation of lipid, remove free radical, promote the cardiovascular system blood flow, antiplatelet aggregation improves immunity of organisms, the effect of selective control estrogen receptor.
This composing prescription preparation has more indication.Wide model over more than 10 years has shown the antipathogen with wide spectrum in using, and improves skin resistance, controls inflammation rapidly, antipruritic, as to promote damaged tissues regeneration and skin ulcer face healing, the effect of avoiding secondary infection.Be applied to the topical therapeutic women's episioitis, vaginitis can control inflammation rapidly, antipruritic, pain relieving, elimination swelling, rotten to the corn effect; Topical therapeutic women urethritis has the effect of rapid alleviation frequent micturition, urgent micturition, dysurea; Topical therapeutic infant eczema, diaper rash have rapidly and control inflammation, and obviously shorten the course of disease, pain relieving is arranged, eliminate erythema, pimple, herpes, antipruritic, promoting muscle growth functions; The topical therapeutic insect dermatitis has antiallergic, rapidly disappear erythema, pimple, welt, the effect of control secondary infection; Topical therapeutic miliaria alba has the macule that disappears rapidly, pimple, antipruritic, as to prevent secondary infection effect; The topical therapeutic condyloma acuminatum, genital herpes has shown antipathogen with wide spectrum, has controlled inflammation rapidly, control and eliminate pimple, vesicle, erosion, ulcer sexually transmitted disease (STD) and become, control and have a joke, the vegetation that disappears, promote repair of damaged tissues, avoid the effect of secondary infection.The child takes a shower with this composing prescription preparation, can effectively prevent the skin infections such as infant eczema, diaper rash, miliaria alba, eliminates rapidly the effect that children's's skin is uncomfortable, protect the tender skin of children's; The women can prevent vulvitis, vaginitis, the inflammation such as urethritis, prevention infection effectively with the demibain of this composing prescription preparation or flushing.
And the externally applied anti-inflammation medicine of this prescription integrates antiinflammatory, irrigation, bath shampoo, pruritus etc., its indication and purposes more than so far still clean, external zijin troche, Chuanbaizhiyang Lotion of the miconazole of extensive use, calamine and menthol lotion, JIEERYIN, woman's inflammation, execute than the medicines such as Ling Zhiyangxiaoyanshui, San Wei Qing Re Zhi Yang Xiji, preparation.And this composing prescription preparation does not add chemical agent, is pure natural medicinal plants preparation; To the adult with infant skin, mucosa, do not have toxic and side effects, nonirritant.
The specific embodiment
The below provides preferred prescription and the preparation technology embodiment of externally applied anti-inflammation medicine of the present invention.
Embodiment one
2 parts of Radix Ophiopogoniss, 1 part of Rhizoma Cibotii, 1 part of Herba Solidaginis, 1 part of Isatis indigotica Fort., 2 parts of Herba Iridis japonicae, 1 part of Herba Taraxaci, 2 parts in Herba Dendranthematis indici; Total amount 1000g.
Preparation process:
Medical material all was crushed to 50 mesh sieve fineness together, added 2kg95% ethanol, airtight dipping medical material 2h; Can obtain the medicated powder that sufficiently uniformly moistening is expanded;
Medicated powder behind the dipping is even, degree of tightness is as one man packed percolator into, and for guaranteeing that degree of tightness is consistent, the spy arranges the dividing plate with holes of layering; Add 2kg 95% ethanol, airtight dipping 48h;
Flow out 2mL speed percolation with medical material 1000g per minute, synchronized adding 60% ethanol, addition is 2kg; Collection is filtered and is got percolate (1) when liquid measure reaches 3.5kg;
Continuous percolation, synchronized adding purified water, addition are 2kg; Collection is filtered and is got percolate (2) when liquid measure reaches 2kg;
Continuous percolation ends to the liquid of filtering is colourless, obtains the continuous liquid of filtering;
Percolate (1), (2) get concentrated solution behind Recycled ethanol; The continuous liquid of filtering that adds this prescription medical material weight 1/2nd weight in the concentrated solution, leaves standstill, considered at mixing, and it is quantitative that 1ml is equivalent to the finished product of crude drug 1g to add the continuous liquid of filtering again.
Embodiment two
3 parts of Radix Ophiopogoniss, 2 parts of Rhizoma Cibotii, 2 parts of Herba Solidaginiss, 1 part of Isatis indigotica Fort., 3 parts of Herba Iridis japonicae, 2 parts of Herba Taraxacis, 3 parts in Herba Dendranthematis indici; Total amount 1000g.
Preparation process:
Medical material all was crushed to 30 mesh sieve fineness together, added 2kg95% ethanol, airtight dipping medical material 2h; Obtain the medicated powder that sufficiently uniformly moistening is expanded;
Medicated powder behind the dipping percolator of evenly, loosely packing into adds 2kg 95% ethanol, airtight dipping 48h;
Flow out 2mL speed percolation with medical material 1000g per minute, synchronized adding 60% ethanol, addition is 2kg; Collection is filtered and is got percolate (1) when liquid measure reaches 3.5kg;
Continuous percolation, synchronized adding purified water, addition are 2kg; Collection is filtered and is got percolate (2) when liquid measure reaches 2kg;
Continuous percolation ends to the liquid of filtering is colourless, obtains the continuous liquid of filtering;
Percolate (1), (2) get concentrated solution behind Recycled ethanol; The continuous liquid of filtering that adds this prescription medical material weight 1/2nd weight in the concentrated solution, leaves standstill, considered at mixing, and it is quantitative that 1ml is equivalent to the finished product of crude drug 1g to add the continuous liquid of filtering again.
Embodiment three
3 parts of Radix Ophiopogoniss, 3 parts of Rhizoma Cibotii, 3 parts of Herba Solidaginiss, 1 part of Isatis indigotica Fort., 4 parts of Herba Iridis japonicae, 2 parts of Herba Taraxacis, 2 parts in Herba Dendranthematis indici; Total amount 1000g.
Preparation method is with embodiment one.
Embodiment four
4 parts of Radix Ophiopogoniss, 3 parts of Rhizoma Cibotii, 3 parts of Herba Solidaginiss, 2 parts of Isatis indigotica Fort., 4 parts of Herba Iridis japonicae, 3 parts of Herba Taraxacis, 3 parts in Herba Dendranthematis indici; Total amount 1000g.
Preparation method is with embodiment one.
This composing prescription preparation is applicable to women's episioitis, vaginitis, and urethritis, infant eczema, diaper rash, the topical therapeutic of the skin infection illness such as insect dermatitis, miliaria alba is applicable to condyloma acuminatum, the topical therapeutic of genital herpes; Also be applicable to prevent the skin infections such as infant eczema, diaper rash, miliaria alba, be applicable to prevent women's episioitis, vaginitis, the inflammation such as urethritis.
Usage and dosage:
A. local wiping: get sterilized cotton swabs (gauze) and dip this preparation wiping affected part or dip this preparation with gauze and roll over to open and be applied to the affected part.
B. the demibain of being grown up: with this preparation and clean warm water 1:19 or 1:49(V:V) after the dilution, be used for demibain.Use every day 1~2 time or do not wait for several times, according to being used for the treatment of or being used for prevention and decide, general prevention once a day, and employing 1:49(V:V) concentration gets final product.
C. child's shower: with this preparation and clean warm water 1:49 or 1:99(V:V) after the dilution, be used for the child and take a shower.Use every day 1~2 time or do not wait for several times, according to being used for the treatment of or being used for prevention and deciding.
D. gynaecologic processing: be applicable to the treatment of the daily flushing cleaning vagina of women and vagina.With this preparation and clean warm water 1:9 or 1:19(V:V) after the dilution, pour into special flusher, be used for flushing.Every day 1-2 time or several do not wait, and decide according to being used for the treatment of or being used for to prevent.
E. soak: be used for male patients with condyloma acuminata, the topical therapeutic of skin lesion due to the genital herpes.This preparation and clean warm water 1:9 or 1::19(V:V) after the dilution, contain to enter to soak with in the container, soak the skin lesion position, each 20~30 minutes, decided according to the patient every day for several times.
Points for attention:
A. this preparation is the external preparation of topical therapeutic (prevention) usefulness, whether carries out simultaneously associated treatment or systemic treatment when using this preparation for treating and should be determined according to conditions of patients by the doctor.
B. demibain, flushing, immersion institute water must be clean warm water, and water temperature is between 37~40 ℃.
C. each demibain, soak finish after, wipe away driedly, keep the skin lesion part clean, dry.
D. menstrual period or colporrhagia phase are forbidden gynaecologic processing, the careful gynaecologic processing of using of anemia of pregnant woman.
E. flusher must be used aseptic irrigator.
F. a people one usefulness such as " bubble basin ", " soak use container ", " flusher ", " bath towel " are forbidden cross-reference.
G. Zuo Yu Time has the people to manage, as the dizzy Li evil of Halo occuring, emitting the Should such as cold sweat to stop immediately demibain.
The effect of this composing prescription preparation
This composing prescription preparation in the application over year, shows safety more than 10, effectively.Do not occur Mucocutaneous paying property of thorn, without sensitization, nontoxic, have no side effect.Be used for topical therapeutic " vaginitis, vulvitis, pruritus vulvae; vulval ulcer, female urethra is scorching, bady's diaper disease, erythema, miliaria alba and mosquito bite " and have uniqueness, significant effect, especially with " demibain " control female vagina, vulvitis, urethritis, " demibain " combination " flushing " control female vagina, " demibain " treatment vulvitis, pruritus vulvae and " children, children's take a shower " prevention bady's diaper disease, erythema, miliaria alba etc. can be received the therapeutic effect that gets instant result.Therapeutic effect than the similar preparation of doctor trained in Western medicine, the traditional Chinese medical science has comparative advantages.Now be the health-care good product of herbal.
1, observe for " children, children's take a shower " more than 30 examples, they with this preparation wiping control infant eczema, diaper rash, obtain remarkable result at cradle, after 3 months, use this preparation " shower " person, all do not suffer from eczema, diaper rash, erythema, preventive effect is remarkable.
2, more than 100 routine women use this preparation " demibain " and wiping treatment urethritis, vulvitis, pruritus vulvae, in for the first time treatment, frequent micturition, urgent micturition, dysurea symptom, pruritus vulvae causalgia symptom etc. are alleviated at once, for the second time after the treatment, above-mentioned symptom and leucorrhea abnormal lapse to gradually, light disease person clinical cure.Receive the therapeutic effect that gets instant result.Daily for cleaning " privates ", effectively prevented urethritis, vaginitis, the generation of vulvitis.
3, prevent and treat miliaria alba with this preparation in " children, children's take a shower ", after once taking a shower, " miliaria " that has occured gradually row disappears, and secondary infection does not occur; Summer and autumn with this preparation in taking a shower ", effectively prevent and treat child, child's miliaria alba.
4, with this preparation for treating " insect dermatitis ", received at once antipruritic, ease the pain and swelling, the prevention secondary infection positive effect.
5, the cauliflower form vegetation with the wiping of this preparation, soaking therapy male patients with condyloma acuminata more than 10 examples one all interior condyloma acuminatum is eliminated, and secondary infection is controlled; With the wiping of this preparation, soaking therapy genital herpes more than 10 examples, red and swollen, pain disappears; The dry incrustation of rotten to the corn face after vesicle is broken is without secondary infection.

Claims (10)

1. externally applied anti-inflammation medicine is comprised of the component of following weight ratio:
2~4 parts of Radix Ophiopogoniss;
1~3 part of Rhizoma Cibotii;
1~3 part of Herba Solidaginis;
1~2 part of Isatis indigotica Fort.;
2~4 parts of Herba Iridis japonicae;
1~3 part of Herba Taraxaci;
2~3 parts in Herba Dendranthematis indici.
2. a kind of externally applied anti-inflammation medicine according to claim 1 is characterized in that: 3 parts of described Radix Ophiopogoniss, 2 parts of Rhizoma Cibotii, 2 parts of Herba Solidaginiss, 1 part of Isatis indigotica Fort., 3 parts of Herba Iridis japonicae, 2 parts of Herba Taraxacis, 3 parts in Herba Dendranthematis indici.
3. a kind of externally applied anti-inflammation medicine according to claim 1 is characterized in that: 3 parts of described Radix Ophiopogoniss, 3 parts of Rhizoma Cibotii, 3 parts of Herba Solidaginiss, 1 part of Isatis indigotica Fort., 4 parts of Herba Iridis japonicae, 2 parts of Herba Taraxacis, 2 parts in Herba Dendranthematis indici.
4. a kind of externally applied anti-inflammation medicine according to claim 1 is characterized in that: 4 parts of described Radix Ophiopogoniss, 3 parts of Rhizoma Cibotii, 3 parts of Herba Solidaginiss, 2 parts of Isatis indigotica Fort., 4 parts of Herba Iridis japonicae, 3 parts of Herba Taraxacis, 3 parts in Herba Dendranthematis indici.
5. according to claim 1 and 2 or 3 or 4 described a kind of externally applied anti-inflammation medicines, it is characterized in that: described externally applied anti-inflammation medicine is prepared as spray or washing liquid.
6. the preparation technology of externally applied anti-inflammation medicine according to claim 5, step comprises:
After this prescription pulverizing medicinal materials with the airtight dipping of 95% ethanol, with medicated powder even moistening degree of being expanded to fully;
Medicated powder behind the dipping is even, degree of tightness is as one man packed percolator into, adds 95% ethanol, and addition is 2 times of this prescription medical material weight, airtight dipping 48h;
Flow out 2mL speed percolation with medical material 1000g per minute, synchronized adding 60% ethanol, addition is 2 times of this prescription medical material weight; Collection is filtered and is got percolate (1) when liquid measure reaches 3.5 times of this prescription medical material weight;
Continuous percolation, synchronized adding purified water, addition are 2 times of this prescription medical material weight; Collection is filtered and is got percolate (2) when liquid measure reaches 2 times of this prescription medical material weight;
Continuous percolation ends to the liquid of filtering is colourless, obtains the continuous liquid of filtering;
Percolate (1), (2) get concentrated solution behind Recycled ethanol; The continuous liquid of filtering that adds this prescription medical material weight 1/2nd weight in the concentrated solution, leaves standstill, considered at mixing, add again the continuous liquid of filtering quantitative finished product.
7. the preparation technology of a kind of externally applied anti-inflammation medicine according to claim 6 is characterized in that: described Recycled ethanol adopts reduced pressure distillation process to carry out.
8. the preparation technology of a kind of externally applied anti-inflammation medicine according to claim 6 is characterized in that: described pulverizing medicinal materials is to the medium powder fineness.
9. the preparation technology of a kind of externally applied anti-inflammation medicine according to claim 6, it is characterized in that: during the airtight dipping medical material of described 95% ethanol, the liquid-solid mass ratio of 95% ethanol and medical material powder is 2:1, airtight placement 2h.
10. the preparation technology of a kind of externally applied anti-inflammation medicine according to claim 6, it is characterized in that: described purified product 1ml is equivalent to crude drug 1g.
CN201210304080.0A 2012-08-23 2012-08-23 External anti-inflammatory drug from the Miao nationality and production process thereof Expired - Fee Related CN102846870B (en)

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CN103655053A (en) * 2013-12-09 2014-03-26 江门市江海区光盛贸易有限公司 Underpants type sanitary napkin with heat-clearing and itch-relieving function
CN103655055A (en) * 2013-12-09 2014-03-26 江门市江海区光盛贸易有限公司 Hook-and-loop fastener pants type sanitary towel

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