CN107753602A - A kind of Chinese medicine composition for treating leukaemia and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating leukaemia and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
Abstract
The invention discloses a kind of Chinese medicine composition for treating leukaemia, include the component of following parts by weight：5~60 parts of 5~40 parts of cherokee rose root, 5~60 parts of common melastoma root, 5~50 parts of hispid fig root, 5~50 parts of white flower pomegranate root and lard.The Chinese medicine composition for the treatment of leukaemia provided by the present invention, using common melastoma root as monarch drug in a prescription, cherokee rose root, lard, hispid fig root and white flower pomegranate root are ministerial drug, higher or relatively low applied to Platelet Index by the synergy of each component, structure adjusting radical cure is carried out to spleen kidney, controlled according to traditional Chinese medical science function of five internal organs is simultaneous, recover internal hemopoietic system, improve the adjustment various indexs of blood, it is kept normal level, thoroughly make hematopoietic function recovery normal for spleen conditioning.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition for treating leukaemia and its preparation side
Method.
Background technology
Leukaemia is mainly the malignant disease of hemopoietic system, is one of domestic ten big malignant tumours occurred frequently.It is characterized in bone
There is the unconfined hyperplasia of a large amount of leukaemias in marrow and other hematopoietic tissues, and enter peripheral blood, and normal plasma cell
Manufacture is substantially suppressed.For the early treatment of leukaemia, clinical more opinions carry out complex treatment, wherein based on chemotherapy,
Treatment by Chinese herbs can be merged can be used bone-marrow transplantation, can be played a part of radical cure with attenuation synergistic, conditions permit.Chemotherapy is leukaemia
Early treatment important method, can effective relief of symptoms, extend life cycle, and chemotherapy is also the necessary step before bone-marrow transplantation
Suddenly.From the point of view of present therapeutic scheme, chemotherapy is an important means, and the later stage still needs to change stem cell, and its chemotherapy process is made
The immunosupress of adult body, stomach and intestine suppress, and the toxic side effect to human body is very big.
The content of the invention
The first object of the present invention is to solve the above problems, there is provided a kind of Chinese medicine composition that can effectively treat leukaemia.
Technical scheme is used by realize the first purpose：
A kind of Chinese medicine composition for treating leukaemia, include the component of following parts by weight：5~40 parts of cherokee rose root, it is wild male
5~60 parts of red 5~60 parts of root, 5~50 parts of hispid fig root, 5~50 parts of white flower pomegranate root and lard.
Cherokee rose root, the evergreen climber of the rose family, alias：Jin Ying Jiang, de- bone are red, be the rosaceous plant fruit of Cherokee rose root or
Root skin.It is usually used in astringent sperm contracting urine, relieving diarrhea with astringents, there is the effect for the treatment of kidney deficiency gonorrhoea.
Common melastoma root, it is the root of Melastomateae plants tomonea, there is the effect of invigorating spleen to remove dampness, promoting blood circulation and hemostasis, control digestion
It is bad, have a stomachache, write dysentery, have blood in stool, bleeding from five sense organs or subcutaneous tissue, menorrhalgia, rheumatalgia pain and traumatic injury.
Hispid fig root, Urticales category moraceae plants, be moraceae plants ficus simplicissima root, be born in hillside, cheuch, roadside
In bushes, south China and the west and south are distributed.There are strengthening the spleen and tonifying the lung, dampness removing relaxing muscles and tendons.
White flower pomegranate root, Punicaceae plant category Punicaceae kind, for the root of the white pomegranate of Punicaceae plant or the white pomegranate of polyphyll.
Effect：Clearing heat and detoxicating, carbuncle that disappears dissipating bind, inducing diuresis for removing edema.
Lard, it is sweet, it is cool in nature, it is nontoxic；There is qi-restoratives, moisturize and detoxify.
Preferably, a kind of Chinese medicine composition for treating leukaemia, the component of following parts by weight is included：8 parts of cherokee rose root, it is wild
8 parts of 15 parts of tree peony root, 8 parts of hispid fig root, 8 parts of white flower pomegranate root and lard.
Preferably, if patient adds following weight in itself with hypertension in the Chinese medicine composition for the treatment of leukaemia
The component of number：5~40 parts of Chinese mesona herb.
Chinese mesona herb, alias：Celestial grass, Mesona chinensis Benth, celestial being's jelly, firewood grass, it is the herb of labiate Chinese mesona herb, is distributed China
South, originate in Guangdong.With clear heat, quench one's thirst, except heat toxin the effect of.Control heatstroke, quench one's thirst, hypertension, muscle, arthralgia.
Preferably, a kind of Chinese medicine composition for treating leukaemia, the component of following parts by weight is included：8 parts of cherokee rose root, it is wild
8 parts of 15 parts of tree peony root, 10 parts of Chinese mesona herb, 8 parts of hispid fig root, 8 parts of white flower pomegranate root and lard.
Preferably, if her white blood cell is low or insufficiency of vital energy and blood, added in the Chinese medicine composition for the treatment of leukaemia with
The component of lower parts by weight：5~40 parts of jujube, 5~40 parts of the Radix Astragali, 1~40 part of saline cistanche, 1~40 part of red ginseng, hawthorn 1~40
Part, 5~40 parts of rice sprout, 5~40 parts of Fructus Aurantii, 1~40 part of almond.
Jujube, there is the effect of tonifying middle-Jiao and Qi, nourishing blood and tranquilization, strengthening the spleen and stomach.Control spleen eating less, weak loose stool, hysteria of womam.
It is the good health nutrient of the patient such as weakness of the spleen and the stomach, insufficiency of vital energy and blood, lassitude, insomnia.
The Radix Astragali, also known as astragali, it is the dry root of legume astragalus mongolicus or Astragalus membranacus.There are invigorating qi for strengthening superficies, diuresis to disappear
The effect of swollen, pus draining and toxin expelling, expelling pus and promoting granulation.Have enhancing body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and
Wide antibacterial action.
Saline cistanche, it is the fleshy stem of orobanchaceae plant cistanche or desert cistanche, fan saline cistanche etc..Have kidney tonifying, strengthening the essence, moisturize,
Laxation effect, cure mainly impotence in male, female sterility, band under, metrorrhagia, waist and knee crymodynia, blood depletion constipation.
Red ginseng, red ginseng are called circle ginseng, ginseng, be the effect of red ginseng reinforce vital energy, veins takes off admittedly, nourishing qi to stop, red ginseng
Effect be tonifying Qi, enriching yin, beneficial blood, promote the production of body fluid, cardiac stimulant, stomach invigorating, calmness, control it is physically weak to be taken off, cold weak pulse of limb, under Qi dysfunction in blood control, uterine bleeding
Blood, heart failure, cardiogenic shock.
Hawthorn, is made medicinal with fruit, is had food digesting stomach fortifying, is activated blood circulation and dispersed blood clots, the function of convergence and dysentery.To meat product phlegm and retained fluid, feeling of fullness
Acid regurgitation, rush down dysentery intestines wind, pain in the back hernia, postpartum postpartum abdominal pain, lochiorrhagia, pediatric milk food stagnation etc. are effective in cure.
Rice sprout, alias tiller rice, paddy tiller, rice tiller, rice bud.Effect：Promoting digestion and removing indigestion, spleen benefiting and stimulating the appetite.Control dyspepsia stagnation, turgor is let out
Rush down, insufficiency of the spleen few food, beriberi edema.
Fructus Aurantii, is rutaceae bitter orange and its drying immature fruit of variety, is relieving stagnant Qi, OK the effect of Fructus Aurantii
Phlegm, disperse accumulations, the effect of Fructus Aurantii are to control septum pectorale feeling of fullness, the distending pain in hypochondrium, accumulation of food in the stomach and intes tine due to indigestion.
Almond, there are the moist dryness of the lung, relieving cough and asthma, the effect of relaxing bowel.Cough due to consumptive disease, asthma are cured mainly, chest and abdomen are against vexed, intestines
Dry constipation, dry and hard excrement.
Preferably, a kind of Chinese medicine composition for treating leukaemia, the component of following parts by weight is included：8 parts of cherokee rose root, it is wild
15 parts of tree peony root, 8 parts of hispid fig root, 8 parts of white flower pomegranate root, 8 parts of jujube, 8 parts of the Radix Astragali, 8 parts of saline cistanche, 8 parts of red ginseng, hawthorn
8 parts, 8 parts of rice sprout, 8 parts of Fructus Aurantii, 8 parts of 8 parts of almond and lard.
Preferably, a kind of Chinese medicine composition for treating leukaemia of the invention, can directly pulverize or by ability
Active component of the conventional extraction techniques such as Hydrolysis kinetics of water extracting alcohol method or alcohol water lifting method in domain as the composition for the treatment of.The work
Property composition can be with pharmaceutically acceptable carrier or excipient.Wherein described pharmaceutically acceptable carrier or excipient according to
Different dosage form and select.The Chinese medicine composition of the present invention is prepared to tablet, pill, medicinal tea, capsule or syrup.
The second object of the present invention is to provide a kind of preparation method for the Chinese medicine composition for treating leukaemia.
Technical scheme is used by realize the second purpose：
A kind of preparation method for the Chinese medicine composition for treating leukaemia, comprises the following steps：
S1, each component in Chinese medicine composition cleaned and sterilization processing；
S2, each component mixed, then coarse crushing is into powder, and powder is counted accurately as 100~150 mesh；
S3, the powder after coarse crushing is put into micro jet it is crushed to 1000~2000 mesh；
S4, carry out breaking-wall cell processing and biological extraction processing；
S5, refined, product is finally made.
The beneficial effects of the invention are as follows：
1st, it is provided by the present invention treatment leukaemia Chinese medicine composition, using common melastoma root as monarch drug in a prescription, cherokee rose root, lard,
Hispid fig root and white flower pomegranate root are ministerial drug, higher or relatively low applied to Platelet Index by the synergy of each component,
Structure adjusting radical cure is carried out to spleen kidney, controlled according to traditional Chinese medical science function of five internal organs is simultaneous, recovers internal hemopoietic system, improves adjustment blood
Various indexs, it is kept normal level, thoroughly make hematopoietic function recovery normal for spleen conditioning.
2nd, the preparation method of the Chinese medicine composition for the treatment of leukaemia provided by the present invention, by rational preparation technology,
The active ingredient of each component is extracted, reduces the loss of active ingredient, is prepared simple and convenient.
Embodiment
With reference to specific embodiment, the present invention is described further：
Embodiment one
A kind of Chinese medicine composition for treating leukaemia that the present embodiment provides, include the component of following parts by weight：Jin Ying
8 parts of 8 parts of root, 15 parts of common melastoma root, 8 parts of hispid fig root, 8 parts of white flower pomegranate root and lard.
Exemplified by producing 1000Kg Chinese medicine compositions：
Said components are cleaned and sterilization processing, after then mixing coarse crushing then put into super into 120 mesh powders
1000 mesh are crushed in Tiny pore pulverizer；Breaking-wall cell processing is carried out again, then is put into the molten device of extraction and carried out biological extraction,
Refined again, finally carry out metering packing.
Embodiment two
A kind of Chinese medicine composition for treating leukaemia that the present embodiment provides, include the component of following parts by weight：Jin Ying
8 parts of 8 parts of root, 15 parts of common melastoma root, 10 parts of Chinese mesona herb, 8 parts of hispid fig root, 8 parts of white flower pomegranate root and lard.
Exemplified by producing 1000Kg Chinese medicine compositions：
Said components are cleaned and sterilization processing, after then mixing coarse crushing then put into super into 150 mesh powders
1500 mesh are crushed in Tiny pore pulverizer；Breaking-wall cell processing is carried out again, then is put into the molten device of extraction and carried out biological extraction,
Refined again, finally carry out metering packing.
Embodiment three
A kind of Chinese medicine composition for treating leukaemia that the present embodiment provides, include the component of following parts by weight：Jin Ying
25 parts of 25 parts of root, 35 parts of common melastoma root, 25 parts of Chinese mesona herb, 27 parts of hispid fig root, 27 parts of white flower pomegranate root and lard.
Exemplified by producing 1000Kg Chinese medicine compositions：
Said components are cleaned and sterilization processing, after then mixing coarse crushing then put into super into 130 mesh powders
1700 mesh are crushed in Tiny pore pulverizer；Breaking-wall cell processing is carried out again, then is put into the molten device of extraction and carried out biological extraction,
Refined again, finally carry out metering packing.
Example IV
A kind of Chinese medicine composition for treating leukaemia that the present embodiment provides, include the component of following parts by weight：Jin Ying
8 parts of root, 15 parts of common melastoma root, 8 parts of hispid fig root, 8 parts of white flower pomegranate root, 8 parts of jujube, 8 parts of the Radix Astragali, 8 parts of saline cistanche, red ginseng
8 parts, 8 parts of hawthorn, 8 parts of rice sprout, 8 parts of Fructus Aurantii, 8 parts of 8 parts of almond and lard.
Exemplified by producing 1000Kg Chinese medicine compositions：
Said components are cleaned and sterilization processing, after then mixing coarse crushing then put into super into 100 mesh powders
2000 mesh are crushed in Tiny pore pulverizer；Breaking-wall cell processing is carried out again, then is put into the molten device of extraction and carried out biological extraction,
Refined again, finally carry out metering packing.
Embodiment five
A kind of Chinese medicine composition for treating leukaemia that the present embodiment provides, include the component of following parts by weight：Jin Ying
35 parts of root, 55 parts of common melastoma root, 45 parts of hispid fig root, 45 parts of white flower pomegranate root, 35 parts of jujube, 35 parts of the Radix Astragali, saline cistanche 35
50 parts of part, 35 parts of red ginseng, 35 parts of hawthorn, 35 parts of rice sprout, 35 parts of Fructus Aurantii, 35 parts of almond and lard.
Exemplified by producing 1000Kg Chinese medicine compositions：
Said components are extracted using traditional Chinese herbs by thermal reflux low temperature extraction low temperature concentration unit extractive technique, Chinese medicine thermal returns
Stream low temperature extraction low temperature concentration unit extractive technique is to combine to decoct extraction, seepage pressure effects, adverse current extraction and backflow extracting four
Kind extraction principle, the extraction of Chinese medicine, concentration two procedures are synchronously carried out, once completion traditional Chinese medicine extraction, novel concentrating process, and change
Become with pressure in the traditional extractor and high temperature decocting process of normal pressure, utilize negative pressure of vacuum, reduce boiling point, carry out low temperature extraction low temperature
Concentration, the operating temperature in extractor is set to control at 40 DEG C~100 DEG C, thickening temperature is controlled at 50 DEG C~80 DEG C, due to using
Negative pressure of vacuum, Chinese herbal medicine cell accelerate expansion, force cell membrane to rupture rapidly, make intracellular active ingredient constantly separation with it is molten
Go out.While indirect steam caused by extraction, concentration is entered into hot reflux condenser into hot condensate liquid, as novel solvent, continuous time
Flow in the medicinal material in extractor, keep higher concentration poor, hot condensate liquid constantly by medicinal material layer, has played dynamic from top to bottom
Diacolation effect is extracted, then extract solution continuously enters inspissator and concentrated.According to practical experience for many years and research, in negative pressure
In the presence of low-temperature vaporization heat, concentration difference is bigger, and effective ingredient recovery rate is higher, and the hot condensate liquid of backflow is about in 2~3 hours
Extractor original solvent is all changed once, makes the solute in extractor in medicinal material tissue in solute and dissolution fluid in the unit interval
A higher concentration difference can be kept, extraction efficiency is higher.
Typical case
First, health XX, man, 9 years old, Third school grade at primary school, performance symptom was weakness of limbs, and spiritual difference sleepy of attending class is felt, build
Become thin, skin surface occurs being on a small quantity maculopapule.
It is below the blood routine comprehensive analysis and marrow picture analysis of examination in hospital：
Blood routine comprehensive analysis：
1st, show positive cell, normochromic anemia, visible normoblast in Blood piece, net stagnant red blood cell and reduce.
2nd, blood platelet：There is plate, the 3rd function blood coagulation work(in 10 × 109/L, Platelet Size, deformity, blood platelet
Can be abnormal.
3rd, leucocyte：36 × 109/L of quantity of leucocyte.
Marrow picture analysis：Initial cell ratio is more than 40%.
It is diagnosed as acute leukemia.
The symptom disappearance after 1 month of above-mentioned Chinese medicine composition is taken, subsequently continues examination in hospital after taking 4 months and reports, it is extensive
It is multiple normal.
2nd, woods XX, man, 53 years old, certain pharmaceutical factory company general manager, shows that four pin are powerless, arthralgia, bleeding gums, walks
Road is difficult, and chemotherapy is crossed once, and skin gray, hospital is diagnosed as chronic myelogenous leukemia.Patient is production medicine, and itself also understands
Many medicines, it is believed that this disease can be cured without medicine.It is initially that pole is mismatched, is given up for lost under the advice of layman.Take above-mentioned
Chinese medicine composition after 1 month symptom mitigation it is a lot, continue examination in hospital after taking a year and a half and return to one's perfect health.
3rd, XX is opened, man, 13 years old, performance symptom was petechial hemorrhage, and persistent fever, bone tenderness, spirit is poor, is fallen ill one month
Afterwards blood Integrated Checkout has been done in hospital：
1st, show positive cell, normochromic anemia, visible normoblast in Blood piece, net stagnant red blood cell and reduce.
2nd, 8 × 109/L of blood platelet, Platelet Size, deformity, huge blood platelet occurs.
3rd, 296 × 109/L of quantity of leucocyte.
4th, color ultrasound shows hepatosplenomegaly.
The inspection of microscopy blood film is coordinated to be diagnosed as acute leukemia.
Symptom mitigation is many after taking above-mentioned Chinese medicine composition two weeks, continues the various fingers of examination in hospital after taking 6 months
Mark reaches normal level.
One of ordinary skill in the art will be appreciated that embodiment described here is to aid in reader and understands this hair
Bright principle, it should be understood that protection scope of the present invention is not limited to such especially statement and embodiment.This area
Those of ordinary skill can make according to these technical inspirations disclosed by the invention various does not depart from the other each of essence of the invention
The specific deformation of kind and combination, these deform and combined still within the scope of the present invention.
Claims (8)
1. a kind of Chinese medicine composition for treating leukaemia, it is characterised in that include the component of following parts by weight：Cherokee rose root 5~
40 parts, 5~60 parts of common melastoma root, 5~50 parts of hispid fig root, 5~60 parts of 5~50 parts of white flower pomegranate root and lard.
2. the Chinese medicine composition for the treatment of leukaemia according to claim 1, it is characterised in that including following parts by weight
Component：8 parts of 8 parts of cherokee rose root, 15 parts of common melastoma root, 8 parts of hispid fig root, 8 parts of white flower pomegranate root and lard.
3. the Chinese medicine composition for the treatment of leukaemia according to claim 1, it is characterised in that also including following parts by weight
Component：5~40 parts of Chinese mesona herb.
4. the Chinese medicine composition for the treatment of leukaemia according to claim 3, it is characterised in that including following parts by weight
Component：8 parts of 8 parts of cherokee rose root, 15 parts of common melastoma root, 10 parts of Chinese mesona herb, 8 parts of hispid fig root, 8 parts of white flower pomegranate root and lard.
5. the Chinese medicine composition for the treatment of leukaemia according to claim 1, it is characterised in that also including following parts by weight
Component：5~40 parts of jujube, 5~40 parts of the Radix Astragali, 1~40 part of saline cistanche, 1~40 part of red ginseng, 1~40 part of hawthorn, rice sprout 5~
40 parts, 5~40 parts of Fructus Aurantii, 1~40 part of almond.
6. the Chinese medicine composition for the treatment of leukaemia according to claim 5, it is characterised in that including following parts by weight
Component：8 parts of cherokee rose root, 15 parts of common melastoma root, 8 parts of hispid fig root, 8 parts of white flower pomegranate root, 8 parts of jujube, 8 parts of the Radix Astragali, meat desert
8 parts of 8 parts of Rong, 8 parts of red ginseng, 8 parts of hawthorn, 8 parts of rice sprout, 8 parts of Fructus Aurantii, 8 parts of almond and lard.
7. according to the Chinese medicine composition of any described treatment leukaemia of claim 1~6, it is characterised in that：The Chinese medicine group
Compound is prepared to tablet, pill, medicinal tea, capsule or syrup.
8. a kind of preparation method of the Chinese medicine composition for the treatment of leukaemia as described in claim 1~6 is any, its feature exist
In comprising the following steps：
S1, each component in Chinese medicine composition cleaned and sterilization processing；
S2, each component mixed, then coarse crushing is into powder, and powder is counted accurately as 100~150 mesh；
S3, the powder after coarse crushing is put into micro jet it is crushed to 1000~2000 mesh；
S4, carry out breaking-wall cell processing and biological extraction processing；
S5, refined, product is finally made.
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| PCT/CN2018/083122 WO2019104931A1 (en) | 2017-11-30 | 2018-04-13 | Traditional chinese medicine composition for treating leukaemia and preparation method therefor |
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| WO2019104931A1 (en) * | 2017-11-30 | 2019-06-06 | 毛小达 | Traditional chinese medicine composition for treating leukaemia and preparation method therefor |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112088775A (en) * | 2020-06-30 | 2020-12-18 | 灵山县山霖生物技术有限公司 | Method for raising seedlings of hispid fig in test tube |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1518996A (en) * | 2003-01-24 | 2004-08-11 | 范崇宏 | A series of Chinese traditional medicine for treating blood disease |
| CN102327462A (en) * | 2011-09-27 | 2012-01-25 | 中国中医科学院西苑医院 | Traditional Chinese medicine for treating qi and blood insufficiency asthenia diseases of leukemia patients after chemotherapy and method for preparing traditional Chinese medicine preparations |
| CN106389647A (en) * | 2016-11-15 | 2017-02-15 | 林树芳 | Medicine for treating blood diseases |
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| CN106620372A (en) * | 2015-10-27 | 2017-05-10 | 张丕友 | Traditional Chinese medicine composition used for treating leukemia |
| CN107753602A (en) * | 2017-11-30 | 2018-03-06 | 毛小达 | A kind of Chinese medicine composition for treating leukaemia and preparation method thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1518996A (en) * | 2003-01-24 | 2004-08-11 | 范崇宏 | A series of Chinese traditional medicine for treating blood disease |
| CN102327462A (en) * | 2011-09-27 | 2012-01-25 | 中国中医科学院西苑医院 | Traditional Chinese medicine for treating qi and blood insufficiency asthenia diseases of leukemia patients after chemotherapy and method for preparing traditional Chinese medicine preparations |
| CN106389647A (en) * | 2016-11-15 | 2017-02-15 | 林树芳 | Medicine for treating blood diseases |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2019104931A1 (en) * | 2017-11-30 | 2019-06-06 | 毛小达 | Traditional chinese medicine composition for treating leukaemia and preparation method therefor |
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Application publication date: 20180306 |