CN107823291A - Chinese medicine composition of hypertension and preparation method thereof caused by a kind of conditioning diabetes - Google Patents

Chinese medicine composition of hypertension and preparation method thereof caused by a kind of conditioning diabetes Download PDF

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CN107823291A
CN107823291A CN201711244352.1A CN201711244352A CN107823291A CN 107823291 A CN107823291 A CN 107823291A CN 201711244352 A CN201711244352 A CN 201711244352A CN 107823291 A CN107823291 A CN 107823291A
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parts
root
chinese medicine
medicine composition
hypertension
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毛小达
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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Abstract

The invention discloses a kind of Chinese medicine composition for nursing one's health hypertension caused by diabetes, include the components of following parts by weight:2~60 parts of 5~40 parts of cherokee rose root, 5~60 parts of common melastoma root, 5~40 parts of Chinese mesona herb, 5~50 parts of root of pungent litse fruit, 5~50 parts of hispid fig root, 5~50 parts of white flower pomegranate root and lard.The Chinese medicine composition is using common melastoma root as monarch drug in a prescription, cherokee rose root, Chinese mesona herb, root of pungent litse fruit, lard, hispid fig root and white flower pomegranate root are ministerial drug, pass through the synergy of each component, applied to hypertension caused by diabetes, radical cure is adjusted to pancreas spleen kidney, internal islet function can not only be recovered, moreover it is possible to improve the metabolic disorder such as sugar, fat, protein, water and electrolyte so as to reach and keep normal level.

Description

Chinese medicine composition of hypertension and preparation method thereof caused by a kind of conditioning diabetes
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition for nursing one's health hypertension caused by diabetes And preparation method thereof.
Background technology
As the deterioration of people's living standards continue to improve and environment, hypertension, high fat of blood, high cholesterol class are cardiovascular Patient increasingly increases.High blood pressure is a kind of chronic disease, and not only the incidence of disease is high, and is also the important danger of angiocardiopathy Dangerous factor, it can cause the infringement of hyperpietic's brain, the heart, kidney and blood vessel, and cerebral apoplexy, coronary heart disease, the heart can clinically occur The relevant diseases such as not normal, heart failure, renal insufficiency, arterial embolism are restrained, its death rate and disability rate are higher, serious influence Hyperpietic is physically and mentally healthy.
China hyperpietic cumulative year after year at present, medicine traditional Chinese and western medicine is various, and conventional has diuretics, blood vessel dilatation Agent, adrenergic receptor blocker, nervous centralis and sympathetic inhibitor etc..The most contraindication of these medicines and side effect compared with It is more, and patient is also easy to produce drug resistance to multi-medicament, wherein postural hypotension is clinical common side effect.In recent years, in The medicine of medical treatment high blood pressure is more developed and developed, and is found after clinical application for many years and observation, these are matched somebody with somebody Though side has certain the effect of improving blood glucose blood pressure, the taste number of prescription is on the high side, and cost of manufacture is high and can not recover kidney completely The function that pancreas spleen originally has, with the sharp increase of Hypertension number, the needs of Case treatment far can not be met.
The content of the invention
The first object of the present invention is to solve the above problems, there is provided a kind of Chinese medicine group for nursing one's health hypertension caused by diabetes Compound, the Chinese medicine composition can not only slow down, treat hypertension, moreover it is possible to recover internal islet function.
Technical scheme is used by realize the first purpose:The Chinese traditional medicine composition of hypertension caused by a kind of conditioning diabetes Thing, include the component of following parts by weight:5~40 parts of cherokee rose root, 5~60 parts of common melastoma root, 5~40 parts of Chinese mesona herb, Litsea pungens 2~60 parts of 5~50 parts of root, 5~50 parts of hispid fig root, 5~50 parts of white flower pomegranate root and lard.
Cherokee rose root, the evergreen climber of the rose family, alias:Jin Ying Jiang, de- bone are red, be the rosaceous plant fruit of Cherokee rose root or Root skin.It is usually used in astringent sperm contracting urine, relieving diarrhea with astringents, there is the effect for the treatment of kidney deficiency gonorrhoea.
Common melastoma root, it is the root of Melastomateae plants tomonea, there is the effect of invigorating spleen to remove dampness, promoting blood circulation and hemostasis, control digestion It is bad, have a stomachache, write dysentery, have blood in stool, bleeding from five sense organs or subcutaneous tissue, menorrhalgia, rheumatalgia pain and traumatic injury.
Chinese mesona herb, alias:Celestial grass, Mesona chinensis Benth, celestial being's jelly, firewood grass, it is the herb of labiate Chinese mesona herb, is distributed China South, originate in Guangdong.With clear heat, quench one's thirst, except heat toxin the effect of.Control heatstroke, quench one's thirst, hypertension, muscle, arthralgia.
Root of pungent litse fruit, alias:Wooden green pepper root, it is the root of canella Litsea euosma etc..The effect of root of pungent litse fruit, is with making With:Middle benefit gas qi-regulating, eliminating cold to stop pain.Cure mainly pancreas, prostate, stomachache with cool feeling, rheumatoid arthrosis ache, malaria, dysmenorrhoea.
Hispid fig root, Urticales category moraceae plants, be moraceae plants ficus simplicissima root, be born in hillside, cheuch, roadside In bushes, south China and the west and south are distributed.There are strengthening the spleen and tonifying the lung, dampness removing relaxing muscles and tendons.
White flower pomegranate root, Punicaceae plant category Punicaceae kind, for the root of the white pomegranate of Punicaceae plant or the white pomegranate of polyphyll. Effect:Clearing heat and detoxicating, carbuncle that disappears dissipating bind, inducing diuresis for removing edema.
Lard, it is sweet, it is cool in nature, it is nontoxic;There is qi-restoratives, moisturize and detoxify.
Preferably, a kind of Chinese medicine composition for nursing one's health hypertension caused by diabetes, the component of following parts by weight is included: 8 parts of cherokee rose root, 15 parts of common melastoma root, 10 parts of Chinese mesona herb, 15 parts of root of pungent litse fruit, 8 parts of hispid fig root, 8 parts of white flower pomegranate root and 8 parts of lard.
Preferably, a kind of Chinese medicine composition for nursing one's health hypertension caused by diabetes, the component of following parts by weight is included: 20 parts of cherokee rose root, 30 parts of common melastoma root, 20 parts of Chinese mesona herb, 25 parts of root of pungent litse fruit, 25 parts of hispid fig root, 25 parts of white flower pomegranate root With 25 parts of lard.
Preferably, a kind of Chinese medicine composition for nursing one's health hypertension caused by diabetes, the component of following parts by weight is included: 38 parts of cherokee rose root, 56 parts of common melastoma root, 35 parts of Chinese mesona herb, 48 parts of root of pungent litse fruit, 42 parts of hispid fig root, 42 parts of white flower pomegranate root With 45 parts of lard.
Preferably, the Chinese medicine composition of hypertension caused by conditioning diabetes of the invention, can directly pulverize or By this area conventional extraction techniques such as Hydrolysis kinetics of water extracting alcohol method or alcohol water lifting method as treatment composition activity into Point.The active component can be with pharmaceutically acceptable carrier or excipient.Wherein described pharmaceutically acceptable carrier or Excipient selects according to different dosage forms.The present invention Chinese medicine composition be prepared to tablet, pill, medicinal tea, capsule or Syrup.
The second object of the present invention is to provide a kind of preparation side for nursing one's health the Chinese medicine composition of hypertension caused by diabetes Method.
Technical scheme is used by realize the second purpose:The Chinese traditional medicine composition of hypertension caused by a kind of conditioning diabetes The preparation method of thing, comprises the following steps:
S1, each component in Chinese medicine composition cleaned, dedusting and sterilization processing;
S2, each component first put into pulverizer and carry out coarse crushing to 40~80 mesh;
S3 and then the component after coarse crushing is put into micro jet it is crushed to 1000~2000 mesh;
S4, carry out breaking-wall cell processing;
S5, carry out biological extraction processing;
S6, refined, product is finally made.
After the completion of above-mentioned steps, carry out in the edible packaging bag of metering threading or tabletting laminating adhesive is packed.
Preferably, sterilization processing is carried out by sunlight or ultraviolet in the step S1.
The beneficial effects of the invention are as follows:
1st, Chinese medicine composition provided by the present invention, using common melastoma root as monarch drug in a prescription, cherokee rose root, Chinese mesona herb, root of pungent litse fruit, pig Oil, hispid fig root and white flower pomegranate root are ministerial drug, by the synergy of each component, applied to high blood caused by diabetes Pressure, radical cure is adjusted to pancreas spleen kidney, internal islet function can not only be recovered, moreover it is possible to improvement sugar, fat, protein, The metabolic disorder such as water and electrolyte is so as to reaching and keep normal level.
2nd, preparation method of the invention extracts common melastoma root, cherokee rose root, Chinese mesona herb, wood by rational preparation technology Jiang Zigen, hispid fig root and white flower pomegranate root active ingredient, reduce the loss of active ingredient, prepare simple and convenient.
Embodiment
With reference to specific embodiment, the present invention is described further:
Embodiment one
The Chinese medicine composition of hypertension caused by a kind of conditioning diabetes that the present embodiment provides, including following parts by weight Component:8 parts of cherokee rose root, 15 parts of common melastoma root, 10 parts of Chinese mesona herb, 15 parts of root of pungent litse fruit, 8 parts of hispid fig root, white flower pomegranate 8 parts of 8 parts of root and lard.
Exemplified by producing 1000Kg Chinese medicine compositions:
It is degerming and coarse crushing is to 80 mesh that said components clean deinsectization respectively, put into after then being mixed ultra-fine Crushing mechanism carries out air-flow crushing to 2000 mesh, then carries out breaking-wall cell processing, then puts into the molten device of extraction and carry out biological extraction Take, then refined, finally carry out metering packing.
Embodiment two
The Chinese medicine composition of hypertension caused by a kind of conditioning diabetes that the present embodiment provides, including following parts by weight Component:20 parts of cherokee rose root, 30 parts of common melastoma root, 20 parts of Chinese mesona herb, 25 parts of root of pungent litse fruit, 25 parts of hispid fig root, white flower stone 25 parts of 25 parts of pomegranate root and lard.
Exemplified by producing 1000Kg Chinese medicine compositions:
It is degerming and coarse crushing is to 40 mesh that said components clean deinsectization respectively, put into after then being mixed ultra-fine Crushing mechanism carries out air-flow crushing to 1000 mesh, then carries out breaking-wall cell processing, then puts into the molten device of extraction and carry out biological extraction Take, then refined, finally carry out metering packing.
Embodiment three
The Chinese medicine composition of hypertension caused by a kind of conditioning diabetes that the present embodiment provides, including following parts by weight Component:38 parts of cherokee rose root, 56 parts of common melastoma root, 35 parts of Chinese mesona herb, 48 parts of root of pungent litse fruit, 42 parts of hispid fig root, white flower stone 50 parts of 42 parts of pomegranate root and lard.
Exemplified by producing 1000Kg Chinese medicine compositions:
Said components are extracted using traditional Chinese herbs by thermal reflux low temperature extraction low temperature concentration unit extractive technique, Chinese medicine thermal returns Stream low temperature extraction low temperature concentration unit extractive technique is to combine to decoct extraction, seepage pressure effects, adverse current extraction and backflow extracting four Kind extraction principle, the extraction of Chinese medicine, concentration two procedures are synchronously carried out, once completion traditional Chinese medicine extraction, novel concentrating process, and change Become with pressure in the traditional extractor and high temperature decocting process of normal pressure, utilize negative pressure of vacuum, reduce boiling point, carry out low temperature extraction low temperature Concentration, the operating temperature in extractor is set to control at 40 DEG C~100 DEG C, thickening temperature is controlled at 50 DEG C~80 DEG C, due to using Negative pressure of vacuum, Chinese herbal medicine cell accelerate expansion, force cell membrane to rupture rapidly, make intracellular active ingredient constantly separation with it is molten Go out.While indirect steam caused by extraction, concentration is entered into hot reflux condenser into hot condensate liquid, as novel solvent, continuous time Flow in the medicinal material in extractor, keep higher concentration poor, hot condensate liquid constantly by medicinal material layer, has played dynamic from top to bottom Diacolation effect is extracted, then extract solution continuously enters inspissator and concentrated.According to practical experience for many years and research, in negative pressure In the presence of low-temperature vaporization heat, concentration difference is bigger, and effective ingredient recovery rate is higher, and the hot condensate liquid of backflow is about in 2~3 hours Extractor original solvent is all changed once, makes the solute in extractor in medicinal material tissue in solute and dissolution fluid in the unit interval A higher concentration difference can be kept, extraction efficiency is higher.
Typical case
1st, Wu XX, female, 29 years old, there is family's tendentiousness, be diagnosed as diabetes after having given birth within 26 years old child, health after taking medicine 4 months It is multiple normal.
Examination in hospital data are within 2009:(1) casual plasma glucose concentration 14.1mmlo/ liters.(2) fasting plasma grape Sugared concentration 8.1mmol/ liters.(3) postprandial two hours plasma glucose concentrations 10.1mmol/ liters of carbohydrate tolerance test,
Take above-mentioned Chinese medicine composition after 4 months examination in hospital data be:(1) casual plasma glucose concentration 10.1mmlo/ liters.(2) fasting plasma glucose concentration 4.9mmol/ liters.(3) postprandial two hours plasma glucoses of carbohydrate tolerance test Sugared concentration 10.0mmol/ liters.
2nd, Lee XX, man, 58 years old, diabetes 8 years, diabetes type II was with hypertension, and control of taking medicine throughout the year is had no result, in hospital Beat insulin and maintain half a year, rehabilitation in 8 months is normal after taking above-mentioned Chinese medicine composition.
Take above-mentioned Chinese medicine composition after 8 months examination in hospital data be:(1) casual plasma glucose concentration 9.1mmlo/ Rise.(2) fasting plasma glucose concentration 5.3mmol/ liters.(3) postprandial two hours plasma glucose concentrations of carbohydrate tolerance test 9mmol/ liters.
3rd, Qiu XX, female, 65 years old, diabetes 5 years, Symptoms were dry, more, the fatigue and weak of urine frequency, hypertension, agriculture Village's domestic conditions difference does not conduct a survey to hospital, is determined as diabetes, takes the rehabilitation after 6 months of above-mentioned Chinese medicine composition.
It is to data of examination in hospital after rehabilitation:(1) casual plasma glucose concentration 9.8mmlo/ liters.(2) fasting blood Starch concentration of glucose 5.5mmol/ liters.(3) postprandial two hours plasma glucose concentrations 8.0mmol/ liters of carbohydrate tolerance test.
One of ordinary skill in the art will be appreciated that embodiment described here is to aid in reader and understands this hair Bright principle, it should be understood that protection scope of the present invention is not limited to such especially statement and embodiment.This area Those of ordinary skill can make according to these technical inspirations disclosed by the invention various does not depart from the other each of essence of the invention The specific deformation of kind and combination, these deform and combined still within the scope of the present invention.

Claims (7)

1. a kind of Chinese medicine composition for nursing one's health hypertension caused by diabetes, it is characterised in that include the group of following parts by weight Point:5~40 parts of cherokee rose root, 5~60 parts of common melastoma root, 5~40 parts of Chinese mesona herb, 5~50 parts of root of pungent litse fruit, hispid fig root 5~ 50 parts, 2~60 parts of 5~50 parts of white flower pomegranate root and lard.
2. it is according to claim 1 conditioning diabetes caused by hypertension Chinese medicine composition, it is characterised in that including with The component of lower parts by weight:8 parts of cherokee rose root, 15 parts of common melastoma root, 10 parts of Chinese mesona herb, 15 parts of root of pungent litse fruit, hispid fig root 8 Part, 8 parts of 8 parts of white flower pomegranate root and lard.
3. it is according to claim 1 conditioning diabetes caused by hypertension Chinese medicine composition, it is characterised in that including with The component of lower parts by weight:20 parts of cherokee rose root, 30 parts of common melastoma root, 20 parts of Chinese mesona herb, 25 parts of root of pungent litse fruit, hispid fig root 25 Part, 25 parts of 25 parts of white flower pomegranate root and lard.
4. it is according to claim 1 conditioning diabetes caused by hypertension Chinese medicine composition, it is characterised in that including with The component of lower parts by weight:38 parts of cherokee rose root, 56 parts of common melastoma root, 35 parts of Chinese mesona herb, 48 parts of root of pungent litse fruit, hispid fig root 42 Part, 45 parts of 42 parts of white flower pomegranate root and lard.
5. according to the Chinese medicine composition of hypertension caused by any described conditioning diabetes of Claims 1 to 4, its feature exists In:The Chinese medicine composition is prepared to tablet, pill, medicinal tea, capsule or syrup.
A kind of 6. preparation side of the Chinese medicine composition of hypertension caused by conditioning diabetes as described in Claims 1 to 4 is any Method, it is characterised in that comprise the following steps:
S1, each component in Chinese medicine composition cleaned, dedusting and sterilization processing;
S2, each component first put into pulverizer and carry out coarse crushing to 40~80 mesh;
S3 and then the component after coarse crushing is put into micro jet it is crushed to 1000~2000 mesh;
S4, carry out breaking-wall cell processing;
S5, carry out biological extraction processing;
S6, refined, product is finally made.
7. the preparation method of the Chinese medicine composition of hypertension, its feature caused by conditioning diabetes according to claim 6 It is:Sterilization processing is carried out by sunlight or ultraviolet in the step S1.
CN201711244352.1A 2017-11-30 2017-11-30 Chinese medicine composition of hypertension and preparation method thereof caused by a kind of conditioning diabetes Pending CN107823291A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114404474A (en) * 2022-03-18 2022-04-29 刘凤和 Formula for tonifying qi and generating blood and preparation method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101129526A (en) * 2007-03-29 2008-02-27 王成禄 Chinese medicine for treating diabetes
CN102406171A (en) * 2011-11-28 2012-04-11 赣南医学院 Health-care food for preventing and treating diabetes and hypertension and preparation method thereof
CN105249469A (en) * 2015-11-24 2016-01-20 冯林 Blood-pressure-lowering instant powder and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101129526A (en) * 2007-03-29 2008-02-27 王成禄 Chinese medicine for treating diabetes
CN102406171A (en) * 2011-11-28 2012-04-11 赣南医学院 Health-care food for preventing and treating diabetes and hypertension and preparation method thereof
CN105249469A (en) * 2015-11-24 2016-01-20 冯林 Blood-pressure-lowering instant powder and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114404474A (en) * 2022-03-18 2022-04-29 刘凤和 Formula for tonifying qi and generating blood and preparation method

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