CN1077435C - Medicine for trachitis and its preparation - Google Patents

Medicine for trachitis and its preparation Download PDF

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CN1077435C
CN1077435C CN99102767A CN99102767A CN1077435C CN 1077435 C CN1077435 C CN 1077435C CN 99102767 A CN99102767 A CN 99102767A CN 99102767 A CN99102767 A CN 99102767A CN 1077435 C CN1077435 C CN 1077435C
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medicine
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CN1230429A (en
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王玉行
武守香
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Abstract

The present invention relates to a medicine for treating trachitis, and a manufacturing method thereof. The medicine is prepared from 1 to 5 parts of platycodon roots, 1 to 5 parts of milkwort, 5 to 20 parts of liquorice extractum powder, 1 to 5 parts of fritillary bulbs, 0.1 to 0.5 parts of bitter apricot seed, 1 to 5 parts of borneol, 0.2 to 0.6 parts of opium powder, 0.1 to 0.5 part of camphor, 2 to 10 parts of aminophylline, 0.001 to 0.01 part of hydrochloric acid clenbuterol, 0.2 to 0.6 part of hydrochloric acid dioxopromethazine, 0 to 0.5 part of prednisone acetate, 0 to 0.5 part of chlorphenamine, 2 to 10 parts of sulfalene oxazole, 0.5 to 5 parts of trimethoprim, 0.1 to 0.3 part of sodium benzoate and 4 to 8 parts of sodium bicarbonate by weight. The medicine combines many traditional Chinese medicines and western medicinal materials according to a proper proportion for mutual coordination and effect improvement in order to obtain the purpose of treating the root cause. The medicine has many effects of sterilization, inflammation removal and asthma alleviation, and particularly has a unique therapeutic effect on radically curing tracheitis.

Description

The medicine and the manufacture method thereof of treatment tracheitis
The present invention relates to medicine and manufacture method thereof, refer in particular to a kind of medicine and manufacture method thereof for the treatment of tracheitis.
Present tracheitis harm humans healthy seriously, particularly infant and old people Geng Yi suffer from tracheitis, generally cooperate the downern inflammation-diminishing and cough-controlling again with antibiotic, but the general treatment effect is slow, can only mitigate the disease, can not thoroughly cure, cause outbreak repeatedly.
The inventor is engaged in curative activity decades, through long term studies and practice, creates technical scheme of the present invention.
The object of the present invention is to provide a kind of medicine and manufacture method thereof for the treatment of tracheitis, by with plurality of Chinese and Western medicine material by the medicine that appropriate proportioning is combined into, have sterilization, relieving asthma, multiple efficacies such as antiinflammatory, reach the purpose of radical cure tracheitis.
The object of the present invention is achieved like this: a kind of medicine for the treatment of tracheitis is characterized in that this medicine forms (parts by weight) by following compositions and proportioning:
Radix Platycodonis 1-5, Radix Polygalae 1-5, Radix Glycyrrhizae extractum powder 5-20, Bulbus Fritillariae Cirrhosae 1-5, Semen Armeniacae Amarum 0.1-0.5, Borneolum Syntheticum 1-5, powdered opium 0.2-0.6, Camphora 0.1-0.5, aminophylline 2-10, clenbuterol hydrochloride 0.001-0.01, dioxopromethazine hydrochloride 0.2-0.6, prednisolone acetate 0-0.5, chlorphenamine 0-0.5, Sulfamethoxazole 2-10, trimethoprim 0.5-5, sodium benzoate 0.1-0.3, sodium bicarbonate 4-8.
Wherein the molecular formula of aminophylline is C 2H 8N 2(C 7H 8N 4O 2) 2H 2O,
The molecular formula of clenbuterol hydrochloride is C 12H 18ClN 2OHCl,
The molecular formula of dioxopromethazine hydrochloride is C 17H 20N 2O 2SHCl,
The molecular formula of prednisolone acetate is C 23H 28O 6,
The molecular formula of chlorphenamine is C 16H 14ClN 3O.
A kind of manufacture method for the treatment of the tracheitis medicine is characterized in that this manufacture method comprises the steps:
(1) select each ingredient and proportioning (parts by weight):
Radix Platycodonis 1-5, Radix Polygalae 1-5, Radix Glycyrrhizae extractum powder 5-20, Bulbus Fritillariae Cirrhosae 1-5, Semen Armeniacae Amarum 0.1-0.5, Borneolum Syntheticum 1-5, powdered opium 0.2-0.6, Camphora 0.1-0.5, aminophylline 2-10, clenbuterol hydrochloride 0.001-0.01, dioxopromethazine hydrochloride 0.2-0.6, prednisolone acetate 0-0.5, chlorphenamine 0-0.5, Sulfamethoxazole 2-10, trimethoprim 0.5-5, sodium benzoate 0.1-0.3, sodium bicarbonate 4-8.
(2) pulverize mix homogeneously:
Above-mentioned each composition is dried pulverizing respectively, cross the following screen cloth of 80 orders and make fine powder, remix is made mixing fine powders; Or with each composition elder generation mix homogeneously, oven dry was pulverized the following screen cloth of 80 orders and was made mixing fine powders again.
(3) sterilization formed package:
The mixing fine powders of above-mentioned (two) is carried out sterilization treatment with conventional method, make tablet or incapsulate with the tablet machine tabletting and make the capsule molding, dosage form is 0.3-0.5 gram, is packaged into medicine of the present invention.
Major advantage of the present invention is:
1, medicine of the present invention by appropriate proportioning combination, is coordinated potentiation with plurality of Chinese and Western medicine material mutually, reaches the purpose of effecting a permanent cure, and the multiple efficacies of have sterilization, antiinflammatory, relievining asthma has unique curative effect to the radical cure tracheitis especially.Radix Platycodonis wherein has lung qi dispersing, sore-throat relieving, eliminates the phlegm, the effect of cough-relieving; Radix Polygalae wherein has the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminates the phlegm, the repercussive effect; Radix Glycyrrhizae extractum wherein has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, get a breathing space relieving asthma, the effect of coordinating the actions of various ingredients in a prescription; Bulbus Fritillariae Cirrhosae wherein has the effect of clearing heat and moistening lung, preventing phlegm from forming and stopping coughing; Semen Armeniacae Amarum wherein has the lowering the adverse-rising QI to subdue asthma cough-relieving, hot effect falls in loosening bowel to relieve constipation; Borneolum Syntheticum wherein has the effect of the refreshment of having one's ideas straightened out, clearing away heat to alleviate pain; Powdered opium wherein have relieving asthma, the antidiarrheal effect; Camphora wherein has the effect that antiinflammatory is relievingd asthma; Aminophylline wherein has loose smooth muscle, the effect of promoting urination to remove dampness; Clenbuterol hydrochloride wherein is the exciting medicine of adrenoceptor, has the effect of sterilization, dehumidifying; Dioxopromethazine hydrochloride wherein is a cough medicine; It is the adrenocortical hormone medicine that prednisolone acetate is wherein arranged, and has the effect of antiinflammatory, dehumidifying; Chlorphenamine wherein is an anticonvulsant drug, has calmness, hypnotic effect; Sulfamethoxazole wherein is the antibiotic medicine; Trimethoprim wherein is the medicine that is good for the stomach; Sodium bicarbonate wherein has the effect that the protection gastric mucosa is avoided stimulating; Sodium benzoate wherein is an antiseptic, has all medicines of the prolongation effect of effect duration.
2, manufacture method of the present invention is very simple, and raw material abundance, inexpensive does not need special equipment and complicated program, is fit to extensive the manufacturing and small lot batch manufacture on the basis of the existing conditions no matter how simple and crude, is with a wide range of applications.
The present invention is further described below in conjunction with preferred embodiment.
Embodiment 1
The medicine of treatment tracheitis of the present invention is made up of following compositions and proportioning:
Radix Platycodonis 2.3 grams, Radix Polygalae 2.3 grams, Radix Glycyrrhizae extractum powder 12 grams, Bulbus Fritillariae Cirrhosae 2 grams, Semen Armeniacae Amarum 0.2 gram, Borneolum Syntheticum 2.4 grams, powdered opium 0.35 gram, Camphora 0.2 gram, aminophylline 5 grams, clenbuterol hydrochloride 0.03 gram, dioxopromethazine hydrochloride 0.35 gram, prednisolone acetate 0.2 gram, chlorphenamine 0.2 gram, Sulfamethoxazole 5.2 grams, trimethoprim 1 gram, sodium bicarbonate 5 grams, sodium benzoate 0.2 gram.
Its manufacture method is:
(1) at first press mentioned component and proportioning and select raw material:
Radix Glycyrrhizae extractum powder method for making wherein is with the Radix Glycyrrhizae chopping, decocts three times with clear water according to a conventional method, and the aqueous extract that merges three times concentrates, dry, pulverizing, and it is standby to make Radix Glycyrrhizae extractum powder; Semen Armeniacae Amarum is wherein fried to yellow standby with conventional method peeling, reuse slow fire;
(2) pulverize mix homogeneously;
Above-mentioned each composition is dried pulverizing respectively, cross the following screen cloth of 80 orders and make fine powder, remix is made mixing fine powders; Or with each composition elder generation mix homogeneously, oven dry was pulverized the following screen cloth of 80 orders and was made mixing fine powders again;
(3) sterilization formed package:
The mixing fine powders of above-mentioned (two) is carried out sterilization treatment with conventional method, make tablet or incapsulate with the tablet machine tabletting and make the capsule molding, dosage form is 0.3-0.5 gram, is packaged into medicine of the present invention.
Embodiment 2:
The medicine of treatment tracheitis of the present invention is made up of following compositions and proportioning:
Radix Platycodonis 4 grams, Radix Polygalae 2 grams, Radix Glycyrrhizae extractum powder 15 grams, Bulbus Fritillariae Cirrhosae 2.5 grams, Semen Armeniacae Amarum 0.25 gram, Borneolum Syntheticum 3 grams, powdered opium 0.3 gram, Camphora 0.3 gram, aminophylline 3 grams, clenbuterol hydrochloride 0.02 gram, dioxopromethazine hydrochloride 0.25 gram, prednisolone acetate 0.3 gram, Sulfamethoxazole 4 grams, trimethoprim 2 grams, sodium bicarbonate 7 grams, sodium benzoate 0.15 gram.
Its mfg. method is with embodiment 1, so do not repeat.
Embodiment 3:
Clinical drug effect of the present invention.
Each composition all belongs to the ingredient that has no side effect in the medicine of the present invention, respectively has different medicinal efficacies, after appropriate proportioning combination, effect with mutual Synergistic, from clinical practice for many years, cured the tracheitis patient of 1,100 examples, existing 10 cases of only lifting wherein are as follows:
1, Mr. Wang is 18 years old, suffers from bronchitis 2 years, and cold is promptly sent out slightly, during sick sending out cough more than, abundant expectoration is rare clearly, rhinorrhea with clear discharge is breathed heavily and sound.Obey each 1 of medicine of the present invention, every day 3 times, a week back state of an illness takes a favorable turn, the bimester after recover.
2, Mr. Zhang is 61 years old, cough throughout the year, and the half the circumference of the sleeve where it joins the shoulder of panting, larynx sound is rung, and expectorant glues foam, coughs difficulty and coughs up and tell, and the sweating swift pulse is an asthma type chronic bronchitis through the many-side inspection, takes medicines such as clenbuterol, aminophylline throughout the year, and curative effect is very little, and diet day subtracts, and body weight is gradually light.Obey medicine of the present invention, each 2, every day secondary, the state of an illness takes a favorable turn after January, continues to take medicine half a year recovery from illness.
3, Mrs Qian: 29 years old, suffered from bronchitis 3 years, cough night very, itching of the throat, with the passing of time excessive phlegm uncomfortable in chest does not heal, medicine disease controlling such as informal dress BAICHUANPENG, effect is not good enough.Recommend to obey medicine of the present invention after one week through the people, do not cough night, and amount of expectoration is gradually few, obeys for two weeks again and recovers.
4, Mrs Jiang: 60 years old, to suffer from emphysema and reach 15 years, cough is more than, coughs a large amount of sticking expectorant, moving slightly just breathless, body void to the utmost point, action must the people be helped, weather has slightly and turns cold, the state of an illness increases the weight of, and just uses medicines such as penicillin, gentamycin, dexamethasone, and outbreak is repeatedly often arranged.Obey each 2 of medicine of the present invention, every day 3 times, life just can be taken care of oneself after January, is almost recovered after half a year, can go to work in the fields.
5, Mr. Sun: 33 years old, coal miner was suffered from bronchitis 2 years, spat every day incessantly, breathed heavily and sound.Obey ten weeks of medicine of the present invention, amount of expectoration is gradually few, continues clothes and recovers in 4 weeks.
6, Mr. Zhou: 70 years old, to suffer from surplus the bronchitis 20 year, cough is spat, and is moving then breathe heavily very; Weather is cool slightly, and the state of an illness increases the weight of, and with a large amount of inflammation-diminishing and cough-controlling Drug therapys, effect all is unsatisfied with.Take medicine of the present invention after 2 weeks, the state of an illness takes a favorable turn, and continues to take medicine 5 months, and health has recovered health gradually, is almost recovered.
7, CHENNU scholar: 52 years old, suffered from emphysema 5 years, body constitution is relatively poor, and life must the people be looked after, and goes to many hospitals such as Jinan, Liaocheng all to fail to cure.Recommend through the people, take medicine of the present invention January, life just can be taken care of oneself, and can go to work in the fields the half a year of continuing again to take medicine, and she meets the people just to overstate: this medicine is a miraculous cure.
8, Mr. Shi: 27 years old, suffered from chronic bronchitis 4 years, through Drug therapys such as dioxopromethazine commonly used, tetracyclines, cough does not still alleviate.Change clothes medicine of the present invention after 2 weeks, cough with asthma obviously alleviates, and continues to take medicine and recovers half a year.
9, Mr. Zhao: 63 years old, the retired cadre suffered from bronchitis and had a surplus in 3 years, cough all day, and night, more so but amount of expectoration was few, movingly slightly just breathed heavily.Obey each 2 of medicine of the present invention, every day 3 times, do not cough night after two weeks, still has slight asthma, continues to take medicine, and is almost recovered after half a year.
10, Mrs Zheng: 48 years old, suffer from emphysema and had a surplus in 6 years, cough a large amount of sticking expectorant every day, the making a deficient case more deficient of just panting of working slightly, it is not good enough to eat curative effect of medication such as clenbuterol, BAICHUANPENG, and health is also relatively poor.Take medicine of the present invention after February, sticking expectorant does not have, and diet increases, and health takes a favorable turn, and can go to work in the fields, and the recovery from illness in March continues to take medicine.
Medicine of the present invention in a word has the significant curative effect of diseases such as the acute and chronic tracheitis of radical cure, bronchitis, emphysema, asthma.

Claims (4)

1, a kind of medicine for the treatment of tracheitis, it is characterized in that: this medicine is grouped into by the one-tenth of following portions by weight:
Radix Platycodonis 1-5, Radix Polygalae 1-5, Radix Glycyrrhizae extractum powder 5-20, Bulbus Fritillariae Cirrhosae 1-5, Semen Armeniacae Amarum 0.1-0.5, Borneolum Syntheticum 1-5, powdered opium 0.2-0.6, Camphora 0.1-0.5, aminophylline 2-10, clenbuterol hydrochloride 0.001-0.01, dioxopromethazine hydrochloride 0.2-0.6, prednisolone acetate 0-0.5, chlorphenamine 0-0.5, Sulfamethoxazole 2-10, trimethoprim 0.5-5, sodium benzoate 0.1-0.3, sodium bicarbonate 4-8.
2, the medicine of treatment tracheitis as claimed in claim 1 is characterized in that: this medicine is made up of following compositions:
Radix Platycodonis 2.3 grams, Radix Polygalae 2.3 grams, Radix Glycyrrhizae extractum powder 12 grams, Bulbus Fritillariae Cirrhosae 2 grams, Semen Armeniacae Amarum 0.2 gram, Borneolum Syntheticum 2.4 grams, powdered opium 0.35 gram, Camphora 0.2 gram, aminophylline 5 grams, clenbuterol hydrochloride 0.03 gram, dioxopromethazine hydrochloride 0.35 gram, prednisolone acetate 0.2 gram, chlorphenamine 0.2 gram, Sulfamethoxazole 5.2 grams, trimethoprim 1 gram, sodium bicarbonate 5 grams, sodium benzoate 0.2 gram.
3, the medicine of treatment tracheitis as claimed in claim 1 is characterized in that: this medicine is made up of following compositions:
Radix Platycodonis 4 grams, Radix Polygalae 2 grams, Radix Glycyrrhizae extractum powder 15 grams, Bulbus Fritillariae Cirrhosae 2.5 grams, Semen Armeniacae Amarum 0.25 gram, Borneolum Syntheticum 3 grams, powdered opium 0.3 gram, Camphora 0.3 gram, aminophylline 3 grams, clenbuterol hydrochloride 0.02 gram, dioxopromethazine hydrochloride 0.25 gram, prednisolone acetate 0.3 gram, Sulfamethoxazole 4 grams, trimethoprim 2 grams, sodium bicarbonate 7 grams, sodium benzoate 0.15 gram.
4, the manufacture method of the described treatment tracheitis of a kind of claim 1 medicine is characterized in that this manufacture method comprises the steps:
(1) select each ingredient to count with parts by weight:
Radix Platycodonis 1-5, Radix Polygalae 1-5, Radix Glycyrrhizae extractum powder 5-20, Bulbus Fritillariae Cirrhosae 1-5, Semen Armeniacae Amarum 0.1-0.5, Borneolum Syntheticum 1-5, powdered opium 0.2-0.6, Camphora 0.1-0.5, aminophylline 2-10, clenbuterol hydrochloride 0.001-0.01, dioxopromethazine hydrochloride 0.2-0.6, prednisolone acetate 0-0.5, chlorphenamine 0-0.5, Sulfamethoxazole 2-10, trimethoprim 0.5-5, sodium benzoate 0.1-0.3, sodium bicarbonate 4-8;
(2) pulverize mix homogeneously:
Above-mentioned each composition is dried pulverizing respectively, cross the following screen cloth of 80 orders and make fine powder, remix is made mixing fine powders; Or with each composition elder generation mix homogeneously, oven dry was pulverized the following screen cloth of 80 orders and was made mixing fine powders again;
(3) sterilization formed package:
The mixing fine powders of above-mentioned (two) is carried out sterilization treatment with conventional method, make tablet or incapsulate with the tablet machine tabletting and make the capsule molding, dosage form is 0.3-0.5 gram, is packaged into medicine of the present invention.
CN99102767A 1999-03-02 1999-03-02 Medicine for trachitis and its preparation Expired - Fee Related CN1077435C (en)

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Application Number Priority Date Filing Date Title
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CN1077435C true CN1077435C (en) 2002-01-09

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103784708A (en) * 2013-12-12 2014-05-14 济南新起点医药科技有限公司 Compound licorice mixture for meat chicken
CN104840719A (en) * 2015-05-15 2015-08-19 孟智琴 Medicament for treating bronchitis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1122702A (en) * 1994-11-07 1996-05-22 肖汉伦 Medicine for curing trachitis, asthma and pneumonectasis
CN1137409A (en) * 1996-05-10 1996-12-11 郑枢邦 Medicine for treatment of cough and asthma

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1122702A (en) * 1994-11-07 1996-05-22 肖汉伦 Medicine for curing trachitis, asthma and pneumonectasis
CN1137409A (en) * 1996-05-10 1996-12-11 郑枢邦 Medicine for treatment of cough and asthma

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