CN107715010A - A kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis - Google Patents
A kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis, include the raw material of following parts by weight：20~40 parts of smilax, 20~40 parts of field pennycress, 20~40 parts of Sargent gloryvine, 18~25 parts of the seed of cowherb, 6~12 parts of fiveleaf akebia fruit, 15~25 parts of spina gleditsiae, 8~15 parts of acute turpinia leaf, 8~12 parts of Chinese holly, 1~3 part of additives, 0.5~1.5 part of penetrating agent.There is the present invention good kidney-nourishing dampness elimination, promoting blood circulation to lead to turbid, clearing heat and detoxicating, anti-inflammation, eliminating stagnation to stop pain and other effects, rapid-action for treating chronic prostatitis, evident in efficacy, total cure rate is up to 97%, and non-relapse after healing, without any side effects, the Chinese medicine compound prescription enema agent for the treatment of chronic prostatitis proposed by the present invention, its raw material is from reasonable, convenient material drawing, preparation method is simple, and it is low to prepare cost, gained enema agent is convenient to take, is worthy to be popularized.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, more particularly to a kind of Chinese medicine compound prescription bowel lavage for treating chronic prostatitis
Preparation.
Background technology
Chronic prostatitis refers to the chronic inflammation that the various causes of disease cause prostata tissue, is the most common disease of Urology Surgery.
Including chronic bacterial prostatitis and non-bacterial prostatitis two parts.Wherein chronic bacterial prostatitis is mainly disease
Pathogen infection, based on retrograde infection, pathogen is mainly staphylococcus, often there is urinary tract infections breaking-out medical history or preceding repeatedly
Persistently with the presence of pathogenic bacteria in row gland massage liquid.It is scorching caused by the reason for non-bacterial prostatitis is Various Complex and inducement
The crisscross pathological change that disease, immune, neuroendocrine participate in, it is main to cause using urethral stimulant symptom and chronic pelvic pain
Clinical manifestation, and often merge the disease of psychic symptoms, diverse clinical manifestations, the course of disease is slow, protracted course of disease.Prior art
In, based on drug therapy, treatment prostate medication thing mainly includes treatment of chronic prostatitis：Antibiotic, alpha-receptor retardance
Agent, galenical, non-steroid anti-inflammatory drug, M- ARBs and antidepressants and anxiolytic etc., said medicine are used to control
Though treating chronic prostatitis can obtain the effect of certain, the generally existing course for the treatment of length, weak curative effect, it is easy recur, side effect greatly, can not
The defects of radical cure, serious strike is caused to the treatment confidence of patient.In recent years, traditional Chinese medical herbal treatment chronic prostatitis into
In order to a kind of popular.It is used for chronic prostatitis Chinese medicine preparation generally existing complicated component however, existing, compatibility not science,
Materials inconvenience, slowly effect, curative effect leave a question open, and have the defects of certain side effect and preparation technology complexity, cost height etc..Based on upper
Statement is stated, the present invention proposes a kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis.
The content of the invention
The invention aims to solve shortcoming present in prior art, and the one kind proposed treats chronic prostate
Scorching Chinese medicine compound prescription enema agent.
A kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis, include the raw material of following parts by weight：Smilax 20
~40 parts, 20~40 parts of field pennycress, 20~40 parts of Sargent gloryvine, 18~25 parts of the seed of cowherb, 6~12 parts of fiveleaf akebia fruit, spina gleditsiae 15~
25 parts, 8~15 parts of acute turpinia leaf, 8~12 parts of Chinese holly, 1~3 part of additives, 0.5~1.5 part of penetrating agent.
Preferably, described a kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis, including following parts by weight
Raw material：25~35 parts of smilax, 25~35 parts of field pennycress, 25~35 parts of Sargent gloryvine, 20~24 parts of the seed of cowherb, fiveleaf akebia fruit 8~10
Part, 18~22 parts of spina gleditsiae, 10~14 parts of acute turpinia leaf, 9~11 parts of Chinese holly, 1.5~2.5 parts of additives, penetrating agent 0.8~
1.2 part.
Preferably, described a kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis, including following parts by weight
Raw material：30 parts of smilax, 30 parts of field pennycress, 30 parts of Sargent gloryvine, 22 parts of the seed of cowherb, 9 parts of fiveleaf akebia fruit, 20 parts of spina gleditsiae, acute turpinia leaf
12 parts of leaf, 10 parts of Chinese holly, 2 parts of additives, 1 part of penetrating agent.
Preferably, the smilax, field pennycress, the mass ratio of Sargent gloryvine are 1~2:1~2:1~2.
Preferably, the additives are that mass ratio is 18~25:1 aqueous gelatin solution and the mixture of tannic acid, the rush
Penetration enhancer is menthol.
The invention also provides a kind of preparation method for the Chinese medicine compound prescription enema agent for treating chronic prostatitis, including with
Lower step：
S1, by the smilax of the proportion, field pennycress, Sargent gloryvine, the seed of cowherb, acute turpinia leaf and Chinese holly clean drain after
It is added in decocting for Chinese herbal medicine tank, by solid-liquid ratio 1:9.5~12, add purified water soak 0.5~1h after, boil with high heat change slow fire after
It is continuous to decoct 0.2~0.4h, then obtain extract solution A through 175~225 mesh sieve net filtrations；
S2, after the fiveleaf akebia fruit of the proportion and spina gleditsiae are cleaned, it is placed in 75~100 DEG C of drying box and dries to perseverance
Weight, is then added in medicinal herb grinder, fully crushes to obtain 40~80 mesh traditional Chinese medicine fine powder B；
S3, by solid-liquid ratio 1:10~14, the traditional Chinese medicine fine powder B of gained in step S2 is added to 45~65 DEG C of 95% ethanol
In, after 15~22min of ultrasonic extraction, obtain extract solution C；
S4, add 75% ethanol to alcohol content to be 46.5~50.5% the extract solution A of gained in step S1, add step S3
The extract solution C of middle gained, after being uniformly mixed, 28~37h is stood, mixed liquor is filtered to obtain through 250~325 mesh accurate filters
D；
S5, under conditions of 50~60 DEG C, the mixed liquor D of gained in step S4 is concentrated under reduced pressure into relative density as 1.2
~1.25, medicinal extract E is obtained, the additives of the proportion and penetrating agent are added in medicinal extract E, in the environment of 55~68 DEG C, with
After 550~650r/min rotating speed is uniformly mixed, sterilizing, which dispenses, to be produced.
Preferably, traditional Chinese medicine fine powder B particle diameter is 60 mesh in the step S2.
Preferably, medicinal extract E relative density is 1.22 in the step S5.
A kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis proposed by the present invention, from smilax, field pennycress,
Sargent gloryvine, the seed of cowherb, fiveleaf akebia fruit, spina gleditsiae, acute turpinia leaf and the taste Chinese medicine preparation of Chinese holly eight are major ingredient, using smilax, are lost
Sauce grass and the compatibility of Sargent gloryvine act synergistically, and the viscosity and permeability of enema agent as obtained by adding auxiliary material increase, it has good
Turbid, clearing heat and detoxicating, anti-inflammation, eliminating stagnation to stop pain and other effects are led in kidney-nourishing dampness elimination well, promoting blood circulation, are risen for treating chronic prostatitis
Effect is fast, and evident in efficacy, total cure rate is up to 97%, and non-relapse after healing, without any side effects, treatment proposed by the present invention
The Chinese medicine compound prescription enema agent of chronic prostatitis, its raw material is from rationally, and convenient material drawing, preparation method is simple, prepares cost
Low, gained enema agent is convenient to take, is worthy to be popularized.
Embodiment
The present invention is made with reference to specific embodiment further to explain.
Embodiment one
A kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis proposed by the present invention, include the original of following parts by weight
Material：20 parts of smilax, 25 parts of field pennycress, 40 parts of Sargent gloryvine, 18 parts of the seed of cowherb, 6 parts of fiveleaf akebia fruit, 15 parts of spina gleditsiae, acute turpinia leaf 8
Part, 8 parts of Chinese holly, 1 part of additives, 0.5 part of penetrating agent, wherein additives are that mass ratio is 18:1 aqueous gelatin solution and tannic acid
Mixture；Penetrating agent is menthol.
Its preparation method, comprise the following steps：
S1, by the smilax of the proportion, field pennycress, Sargent gloryvine, the seed of cowherb, acute turpinia leaf and Chinese holly clean drain after
It is added in decocting for Chinese herbal medicine tank, by solid-liquid ratio 1:9.5, after adding purified water immersion 0.5h, boil to change with high heat and continue boiling by slow fire
0.2h, then obtain extract solution A through 175 mesh sieve net filtrations；
S2, after the fiveleaf akebia fruit of the proportion and spina gleditsiae are cleaned, it is placed in 75 DEG C of drying box and dries to constant weight, then
It is added in medicinal herb grinder, fully crushes to obtain 40 mesh traditional Chinese medicine fine powder B；
S3, by solid-liquid ratio 1:10, the traditional Chinese medicine fine powder B of gained in step S2 is added in 45 DEG C of 95% ethanol, ultrasound
After extracting 15min, extract solution C is obtained；
S4, add 75% ethanol to alcohol content to be 46.5% the extract solution A of gained in step S1, add gained in step S3
Extract solution C, after being uniformly mixed, stand 28h, filter to obtain mixed liquor D through 250 mesh accurate filters；
S5, under conditions of 50 DEG C, the mixed liquor D of gained in step S4 is concentrated under reduced pressure into relative density as 1.2, must be soaked
Cream E, the additives of the proportion and penetrating agent are added in medicinal extract E, in the environment of 55 DEG C, stirred with 550r/min rotating speed
Mix after being well mixed, sterilizing, which dispenses, to be produced.
Embodiment two
A kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis proposed by the present invention, include the original of following parts by weight
Material：40 parts of smilax, 30 parts of field pennycress, 20 parts of Sargent gloryvine, 25 parts of the seed of cowherb, 12 parts of fiveleaf akebia fruit, 25 parts of spina gleditsiae, acute turpinia leaf
15 parts, 12 parts of Chinese holly, 3 parts of additives, 1.5 parts of penetrating agent, wherein additives are that mass ratio is 25:1 aqueous gelatin solution with
The mixture of tannic acid；Penetrating agent is menthol.
Its preparation method, comprise the following steps：
S1, by the smilax of the proportion, field pennycress, Sargent gloryvine, the seed of cowherb, acute turpinia leaf and Chinese holly clean drain after
It is added in decocting for Chinese herbal medicine tank, by solid-liquid ratio 1:12, after adding purified water immersion 1h, boil to change with high heat and continue boiling by slow fire
0.4h, then obtain extract solution A through 225 mesh sieve net filtrations；
S2, after the fiveleaf akebia fruit of the proportion and spina gleditsiae are cleaned, it is placed in 100 DEG C of drying box and dries to constant weight, so
After be added in medicinal herb grinder, fully crush to obtain 80 mesh traditional Chinese medicine fine powder B；
S3, by solid-liquid ratio 1:14, the traditional Chinese medicine fine powder B of gained in step S2 is added in 65 DEG C of 95% ethanol, ultrasound
After extracting 22min, extract solution C is obtained；
S4, add 75% ethanol to alcohol content to be 50.5% the extract solution A of gained in step S1, add gained in step S3
Extract solution C, after being uniformly mixed, stand 37h, filter to obtain mixed liquor D through 325 mesh accurate filters；
S5, under conditions of 60 DEG C, the mixed liquor D of gained in step S4 is concentrated under reduced pressure into relative density as 1.25, obtained
Medicinal extract E, the additives of the proportion and penetrating agent are added in medicinal extract E, in the environment of 68 DEG C, with 650r/min rotating speed
After being uniformly mixed, sterilizing, which dispenses, to be produced.
Embodiment three
A kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis proposed by the present invention, include the original of following parts by weight
Material：30 parts of smilax, 30 parts of field pennycress, 30 parts of Sargent gloryvine, 22 parts of the seed of cowherb, 9 parts of fiveleaf akebia fruit, 20 parts of spina gleditsiae, acute turpinia leaf
12 parts, 10 parts of Chinese holly, 2 parts of additives, 1 part of penetrating agent, wherein additives are that mass ratio is 22:1 aqueous gelatin solution and tan
The mixture of acid；Penetrating agent is menthol.
Its preparation method, comprise the following steps：
S1, by the smilax of the proportion, field pennycress, Sargent gloryvine, the seed of cowherb, acute turpinia leaf and Chinese holly clean drain after
It is added in decocting for Chinese herbal medicine tank, by solid-liquid ratio 1:10.5, after adding purified water immersion 0.8h, boil to change with high heat and continue boiling by slow fire
0.3h, then obtain extract solution A through 200 mesh sieve net filtrations；
S2, after the fiveleaf akebia fruit of the proportion and spina gleditsiae are cleaned, it is placed in 85 DEG C of drying box and dries to constant weight, then
It is added in medicinal herb grinder, fully crushes to obtain 60 mesh traditional Chinese medicine fine powder B；
S3, by solid-liquid ratio 1:12, the traditional Chinese medicine fine powder B of gained in step S2 is added in 55 DEG C of 95% ethanol, ultrasound
After extracting 18min, extract solution C is obtained；
S4, add 75% ethanol to alcohol content to be 48.5% the extract solution A of gained in step S1, add gained in step S3
Extract solution C, after being uniformly mixed, stand 34h, filter to obtain mixed liquor D through 280 mesh accurate filters；
S5, under conditions of 55 DEG C, the mixed liquor D of gained in step S4 is concentrated under reduced pressure into relative density as 1.22, obtained
Medicinal extract E, the additives of the proportion and penetrating agent are added in medicinal extract E, in the environment of 62 DEG C, with 600r/min rotating speed
After being uniformly mixed, sterilizing, which dispenses, to be produced.
Example IV
A kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis proposed by the present invention, include the original of following parts by weight
Material：25 parts of smilax, 25 parts of field pennycress, 25 parts of Sargent gloryvine, 20 parts of the seed of cowherb, 8 parts of fiveleaf akebia fruit, 18 parts of spina gleditsiae, acute turpinia leaf
10 parts, 9 parts of Chinese holly, 1.5 parts of additives, 0.8 part of penetrating agent, wherein additives are that mass ratio is 19:1 aqueous gelatin solution with
The mixture of tannic acid；Penetrating agent is menthol.
Its preparation method, comprise the following steps：
S1, by the smilax of the proportion, field pennycress, Sargent gloryvine, the seed of cowherb, acute turpinia leaf and Chinese holly clean drain after
It is added in decocting for Chinese herbal medicine tank, by solid-liquid ratio 1:10, after adding purified water immersion 0.7h, boil to change with high heat and continue boiling by slow fire
0.25h, then obtain extract solution A through 185 mesh sieve net filtrations；
S2, after the fiveleaf akebia fruit of the proportion and spina gleditsiae are cleaned, it is placed in 80 DEG C of drying box and dries to constant weight, then
It is added in medicinal herb grinder, fully crushes to obtain 50 mesh traditional Chinese medicine fine powder B；
S3, by solid-liquid ratio 1:11, the traditional Chinese medicine fine powder B of gained in step S2 is added in 50 DEG C of 95% ethanol, ultrasound
After extracting 16min, extract solution C is obtained；
S4, add 75% ethanol to alcohol content to be 47.5% the extract solution A of gained in step S1, add gained in step S3
Extract solution C, after being uniformly mixed, stand 30h, filter to obtain mixed liquor D through 275 mesh accurate filters；
S5, under conditions of 55 DEG C, the mixed liquor D of gained in step S4 is concentrated under reduced pressure into relative density as 1.2, must be soaked
Cream E, the additives of the proportion and penetrating agent are added in medicinal extract E, in the environment of 60 DEG C, stirred with 580r/min rotating speed
Mix after being well mixed, sterilizing, which dispenses, to be produced.
Embodiment five
A kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis proposed by the present invention, include the original of following parts by weight
Material：35 parts of smilax, 35 parts of field pennycress, 35 parts of Sargent gloryvine, 24 parts of the seed of cowherb, 11 parts of fiveleaf akebia fruit, 22 parts of spina gleditsiae, acute turpinia leaf
14 parts, 11 parts of Chinese holly, 2.5 parts of additives, 1.2 parts of penetrating agent, wherein additives are that mass ratio is 24:1 aqueous gelatin solution
With the mixture of tannic acid；Penetrating agent is menthol.
Its preparation method, comprise the following steps：
S1, by the smilax of the proportion, field pennycress, Sargent gloryvine, the seed of cowherb, acute turpinia leaf and Chinese holly clean drain after
It is added in decocting for Chinese herbal medicine tank, by solid-liquid ratio 1:11, after adding purified water immersion 0.9h, boil to change with high heat and continue boiling by slow fire
0.35h, then obtain extract solution A through 210 mesh sieve net filtrations；
S2, after the fiveleaf akebia fruit of the proportion and spina gleditsiae are cleaned, it is placed in 90 DEG C of drying box and dries to constant weight, then
It is added in medicinal herb grinder, fully crushes to obtain 70 mesh traditional Chinese medicine fine powder B；
S3, by solid-liquid ratio 1:13, the traditional Chinese medicine fine powder B of gained in step S2 is added in 60 DEG C of 95% ethanol, ultrasound
After extracting 20min, extract solution C is obtained；
S4, add 75% ethanol to alcohol content to be 49% the extract solution A of gained in step S1, add gained in step S3
Extract solution C, after being uniformly mixed, 35h is stood, mixed liquor D is filtered to obtain through 300 mesh accurate filters；
S5, under conditions of 60 DEG C, the mixed liquor D of gained in step S4 is concentrated under reduced pressure into relative density as 1.24, obtained
Medicinal extract E, the additives of the proportion and penetrating agent are added in medicinal extract E, in the environment of 65 DEG C, with 620r/min rotating speed
After being uniformly mixed, sterilizing, which dispenses, to be produced.
By the Chinese medicine compound prescription enema agent of the treatment chronic prostatitis prepared in the embodiment of the present invention one~tri- with it is commercially available
Certain treatment chronic prostatitis Chinese medicine preparation (making to ratio), be respectively used to treatment with different degrees of urination it is not smooth,
Each 200 of the patients with chronic prostatitis (choosing of the symptoms such as vesical tenesmus, frequent micturition, urgent urination, drop are white, the soreness of waist, perineum falling inflation sense
There was no significant difference in sex, age, the course of disease, the state of an illness etc. for the chronic prostatitis taken, has comparativity), in treatment phase 1
In~5 months, follow-up care effect, following parameter is drawn：
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto,
Any one skilled in the art the invention discloses technical scope in, technique according to the invention scheme and its
Inventive concept is subject to equivalent substitution or change, should all be included within the scope of the present invention.
Claims (8)
1. a kind of Chinese medicine compound prescription enema agent for treating chronic prostatitis, it is characterised in that include the raw material of following parts by weight：
20~40 parts of smilax, 20~40 parts of field pennycress, 20~40 parts of Sargent gloryvine, 18~25 parts of the seed of cowherb, 6~12 parts of fiveleaf akebia fruit, soap
15~25 parts of angle thorn, 8~15 parts of acute turpinia leaf, 8~12 parts of Chinese holly, 1~3 part of additives, 0.5~1.5 part of penetrating agent.
A kind of 2. Chinese medicine compound prescription enema agent for treating chronic prostatitis according to claim 1, it is characterised in that bag
Include the raw material of following parts by weight：25~35 parts of smilax, 25~35 parts of field pennycress, 25~35 parts of Sargent gloryvine, the seed of cowherb 20~24
Part, 8~10 parts of fiveleaf akebia fruit, 18~22 parts of spina gleditsiae, 10~14 parts of acute turpinia leaf, 9~11 parts of Chinese holly, additives 1.5~2.5
Part, 0.8~1.2 part of penetrating agent.
A kind of 3. Chinese medicine compound prescription enema agent for treating chronic prostatitis according to claim 1, it is characterised in that bag
Include the raw material of following parts by weight：30 parts of smilax, 30 parts of field pennycress, 30 parts of Sargent gloryvine, 22 parts of the seed of cowherb, 9 parts of fiveleaf akebia fruit, gleditsia sinensis
20 parts of thorn, 12 parts of acute turpinia leaf, 10 parts of Chinese holly, 2 parts of additives, 1 part of penetrating agent.
A kind of 4. Chinese medicine compound prescription enema agent for treating chronic prostatitis according to claim 1, it is characterised in that institute
It is 1~2 to state smilax, field pennycress, the mass ratio of Sargent gloryvine:1~2:1~2.
A kind of 5. Chinese medicine compound prescription enema agent for treating chronic prostatitis according to claim 1, it is characterised in that institute
It is that mass ratio is 18~25 to state additives:1 aqueous gelatin solution and the mixture of tannic acid, the penetrating agent are menthol.
6. a kind of preparation method of Chinese medicine compound prescription enema agent for treating chronic prostatitis according to claim 1, its
It is characterised by, comprises the following steps：
S1, by the smilax of the proportion, field pennycress, Sargent gloryvine, the seed of cowherb, acute turpinia leaf and Chinese holly clean drain after add
Into decocting for Chinese herbal medicine tank, by solid-liquid ratio 1:9.5~12, after adding purified water to soak 0.5~1h, boil with high heat and change slow fire and continue to decoct
0.2~0.4h is boiled, then obtains extract solution A through 175~225 mesh sieve net filtrations；
S2, after the fiveleaf akebia fruit of the proportion and spina gleditsiae are cleaned, it is placed in 75~100 DEG C of drying box and dries to constant weight, so
After be added in medicinal herb grinder, fully crush to obtain 40~80 mesh traditional Chinese medicine fine powder B；
S3, by solid-liquid ratio 1:10~14, the traditional Chinese medicine fine powder B of gained in step S2 is added in 45~65 DEG C of 95% ethanol,
After 15~22min of ultrasonic extraction, extract solution C is obtained；
S4, add 75% ethanol to alcohol content to be 46.5~50.5% the extract solution A of gained in step S1, add institute in step S3
The extract solution C obtained, after being uniformly mixed, 28~37h is stood, mixed liquor D is filtered to obtain through 250~325 mesh accurate filters；
S5, under conditions of 50~60 DEG C, by the mixed liquor D of gained in step S4 be concentrated under reduced pressure into relative density for 1.2~
1.25, medicinal extract E is obtained, the additives of the proportion and penetrating agent are added in medicinal extract E, in the environment of 55~68 DEG C, with 550
After~650r/min rotating speed is uniformly mixed, sterilizing, which dispenses, to be produced.
7. a kind of preparation method of Chinese medicine compound prescription enema agent for treating chronic prostatitis according to claim 1, its
It is characterised by, traditional Chinese medicine fine powder B particle diameter is 60 mesh in the step S2.
8. a kind of preparation method of Chinese medicine compound prescription enema agent for treating chronic prostatitis according to claim 1, its
It is characterised by, medicinal extract E relative density is 1.22 in the step S5.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112107643A (en) * | 2020-09-25 | 2020-12-22 | 江西中医药大学 | Chinese medicinal compound oral preparation for treating chronic nonbacterial prostatitis and preparation process thereof |
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| WO2000007604A1 (en) * | 1998-08-03 | 2000-02-17 | Wheeler Ronald E | Prostate formula |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000007604A1 (en) * | 1998-08-03 | 2000-02-17 | Wheeler Ronald E | Prostate formula |
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Application publication date: 20180223 |