CN107669956A - Treat dog, the Chinese medicine preparation and preparation method thereof of cat otopathy - Google Patents
Treat dog, the Chinese medicine preparation and preparation method thereof of cat otopathy Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/78—Saururaceae (Lizard's-tail family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A61K9/00—Medicinal preparations characterised by special physical form
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Abstract
The invention discloses it is a kind of treat dog, cat otopathy Chinese medicine preparation and preparation method thereof, it is intended to solve that existing medicine is inconvenient for use, ineffective technical problem.The Chinese medicine preparation is made up of golden cypress, kuh-seng, the tuber of stemona, the root bark of shaggy-fruited dittany, Chinese Fevervine Herb, cordate houttuynia, peppermint, borneol bulk drug, by heating boil obtained by paste missible oil.The Chinese medicine preparation is by traditional Chinese medicine reasonable formula, and each component synergy, preventing and treating pet body surface bacterial fungus infectious effect is notable, be mainly used in treating microorganism and the acarids such as dog, cat ear infections fungi bacterium and caused by the illness such as itch, erythema, depilation；Its preparation method is simple, easy to use, is adapted to the needs of scale industrial production.
Description
Technical field
A kind of medicine in being used the present invention relates to animal, and in particular to Chinese medicine preparation for treating dog, cat otopathy and convenient drug administration
And preparation method thereof.
Background technology
With the development of social economy and the acceleration of urbanization process, people's cultural life and living standard are increasingly
Improve, social senilization's paces are accelerated, and the contacts between people are fewer and fewer, and raising pet has become many people's leisure, put
One of pine and emotion sustenance mode.
At present, pet has entered into common people house, turns into a kind of pastime of people's life.It is except bringing people
It is many it is happy beyond, mental health to the mankind, easing off the pressure is very helpful, often by people it is warm be referred to as that " companion moves
Thing ".However, pet also often suffers from various common diseases, wherein dog, cat otopathy is the most universal, such as otodectic mange.Cause
This, while raising pets quantity is more and more, Medical pet also increasingly causes social concerns.Although China's Medical pet exists
Quickly grow within nearly 10 years, but treatment method relies primarily on doctor trained in Western medicine, and traditional traditional Chinese veterinary medicine in China uses in terms of Medical pet
It is less, do not cause the attention of veterinary industry.
Otodectic mange is to parasitize caused a kind of parasitic disease in animal ear by itch mite or itch mite, is a kind of partial parasite
Worm, easily trigger duct scorching.Due to dog, cat ear around hair it is relatively more, duct is deep, and the inside is easy to collect
Dust, dirt, cleaning are also less susceptible to, and easily trigger disease, and therapeutic process is long, easily repeatedly.According to investigations, dog, notoedres cati
Infection rate is more than 20%, and the ear mite infection rate of rabbit is more than 50%.Ear mite seriously endangers animal health, influences the habit of pet
Property and behavior, influence the production performance of economic animal, or even cause death.
At present, the medicine of a variety for the treatment of animal's ear diseases on growing pet market be present, but mostly deposited
It is long in the course for the treatment of, curative effect unobvious, and occur that animal aches phenomenon of itching in therapeutic process, it is necessary to coordinate analgestic, antipruritic to make
With the problems such as easily causing various allergy, inflammation.And the preparation of animal ear mite more conventional at present mainly contains macrolide
The injection (such as ivermectin injection) of class anti-parasite medicine.Injection is Formulations for systemic administration, there is that dosage is big, cost
It is high, toxicity is big, in-convenience in use the shortcomings of.
As can be seen here, develop a kind of local convenient drug administration, administration less, the low cost pharmaceutical preparation that has no toxic side effect prevents and treats
Pet ear mite is very urgent.
The content of the invention
The technical problem to be solved in the present invention is to provide a kind of reasonable recipe, compatibility degree of having, raw material sources are extensive, to prescription
Just, have no toxic side effect, treatment dog, the Chinese medicine preparation and preparation method thereof of cat otopathy.
In order to solve the above technical problems, the present invention adopts the following technical scheme that：
It is a kind of to treat dog, the Chinese medicine preparation of cat otopathy, it is made up of the bulk drug of following weight：15~35 parts of golden cypress, kuh-seng 15~
30 parts, 10~20 parts of the tuber of stemona, 5~15 parts of the root bark of shaggy-fruited dittany, 5~15 parts of Chinese Fevervine Herb, 5~15 parts of cordate houttuynia, peppermint 5~15
Part, 3~10 parts of borneol.
Preferably, described treatment dog, the Chinese medicine preparation of cat otopathy, are made up of the bulk drug of following weight：Golden cypress 25
Part, 15 parts of kuh-seng, 15 parts of the tuber of stemona, 10 parts of the root bark of shaggy-fruited dittany, 10 parts of Chinese Fevervine Herb, 10 parts of cordate houttuynia, 10 parts of peppermint, borneol 5
Part.
It is further preferred that the peppermint is standard items peppermint oil.
The preparation method of above-mentioned Chinese medicine preparation, including following preparation technology：
（1）Decoct for the first time：Bulk drug golden cypress, kuh-seng, the tuber of stemona, the root bark of shaggy-fruited dittany, Chinese Fevervine Herb, cordate houttuynia are weighed according to proportioning, is put into
Extractor, to extractor plus pure water, is boiled by intense fire, is then cooked by slow fire 25~35 min, by medical filtration to fluid reservoir, the dregs of a decoction
It is recycled to extractor；
（2）Second of decoction：Into the dregs of a decoction plus pure water is extremely equal with powder, boils by intense fire, is then cooked by slow fire 30 min, then will
Medical filtration to fluid reservoir, the dregs of a decoction are recycled to extractor；
（3）Concentration：The decoction for decocting extraction twice is merged, paste is concentrated into, obtains Chinese medicine paste；
（4）Borneol is weighed, is dissolved in after being milled to powder in organic solvent；
（5）Peppermint is weighed, the vaseline after mixing is added together with above-mentioned Chinese medicine paste, borneol, in atoleine, and add
Proper amount of surfactant, bleeding agent, mixing.
Preferably, in the step（1）In, addition pure water extremely exceedes the cm of powder 2~3.
Preferably, in step（4）In, the organic solvent is alcohol.
Preferably, in step（5）In, the vaseline, atoleine are with 1:6 volume ratio mixing.
Preferably, in step（5）In, the bleeding agent is azone.
Compared with prior art, advantageous effects of the invention are：
1. the present invention gropes meticulously by long-term, substantial amounts of practical studies, with reference to modern medicine pharmacological research achievement, develop
And obtain, be mainly used in treating dog, the microorganism such as feline pet ear infections bacterial fungus, and mite infection and caused by scabies
Itch, otitis, the illness such as depilation, therapeutic effect is notable, convenient drug administration, and can effectively avoid the dependence to chemicals.
2. be pure Chinese medicinal preparation in side of the present invention, with golden cypress, kuh-seng collectively as monarch drug in a prescription, heat-clearing, eliminating dampness, except itching；With hundred
Portion, the root bark of shaggy-fruited dittany, Chinese Fevervine Herb are desinsection, antibacterial, antipruritic as adjuvant；Using cordate houttuynia, peppermint, borneol as adjutant, clearing heat and detoxicating,
Ease pain, be antipruritic.
3. raw material sources of the present invention are extensive, by traditional Chinese medicine reasonable formula, specially, compatibility degree of having, each component cooperates with medicinal essence
Effect, all medicines share, curative effect are shown；Chinese medicine preparation of the present invention is paste missible oil, easy to use, is easy to preserve and carries, and nothing
Toxic side effect, treatment cycle is short, and therapeutic effect is obvious.
4. the preparation method of the medicament is simple in the present invention, no complicated equipment and cumbersome technique, scale is facilitated to grasp
Make, cost is cheap, remarkable in economical benefits.
The pharmacological effect of primary raw material medicine is summarized as follows in side：
Golden cypress：Bitter, it is cold in nature.Kidney, bladder warp.There is a heat-clearing and damp-drying drug, purging intense heat, except steaming, the effect of detoxification sore treatment.For sore swollen toxin,
Eczema wet sore.
Kuh-seng：Bitter, it is cold in nature.The thoughts of returning home, liver, stomach, large intestine, bladder warp.Heat-clearing and damp-drying drug, desinsection, diuresis.It is wet for eczema
Sore, pruitus, mange leprosy etc..
The tuber of stemona：It is sweet, bitter, tepor.Return lung passes through.Moistening lung to lower qi cough-relieving, desinsection.It is used for head louse, body louse, enterobiasis, private parts outside
Disturb and itch.
The root bark of shaggy-fruited dittany：It is bitter；It is salty；It is cold.Returns spleen warp, lung channel, small intestinl channel, stomach, bladder warp.Heat-clearing and damp-drying drug, dispelling wind and arresting itching, solution
Poison.For the rubella caused by wind-heat wet poison, eczema, mange, jaundice, damp-heat arthralgia etc..
Chinese Fevervine Herb：It is sweet, sour, it is mild-natured.The thoughts of returning home, liver, spleen, kidney channel.Expelling wind and removing dampness, promoting digestion and removing indigestion, cough-relieving, analgesic.External application
In dermatitis, eczema and sore swollen toxin.
Cordate houttuynia：It is sweet pungent salty, it is nontoxic.Return liver, lung two pass through, clearing heat and detoxicating, inducing diuresis to remove edema.For carbuncle swells, eczema, the favus of the scalp,
Mange etc..
Peppermint：It is pungent, it is cool.Enter lung channel, Liver Channel.Dispelling wind and heat from the body, head clearing, relieving sore-throat promoting eruption, soothing the liver promoting the circulation of qi.For skin wind
The diseases such as rash itching, measles without adequate eruption, it is also effective to carbuncle, subcutaneous ulcer, scabies, tinea, dermatitis rhus in addition.
Borneol：It is arduous, it is cool.Enter the heart, Liver Channel.Cure mainly high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, apoplexy coma due to blocking of the respiratory system shies epilepsy, summer-heat and damp blinds clear key, larynx
Numbness is deaf, aphtha tooth swells, sore carbuncle infantile malnutrition due to digestive disturbances or intestinalparasites hemorrhoid, red eye, swell pain, pterygium.
Embodiment
Technical scheme is described in detail with reference to specific embodiment, but following examples are not in any way
Limit the scope of the present invention.Involved reagent is commercially available conventional reagent unless otherwise instructed in following examples.
Embodiment 1
It is a kind of to treat dog, the Chinese medicine preparation of cat otopathy, it is made up of the following raw material medicine：
Monarch drug in a prescription：The g of golden cypress 25, the g of kuh-seng 15；Ministerial drug：The g of the tuber of stemona 15, the g of the root bark of shaggy-fruited dittany 10, the g of Chinese Fevervine Herb 10；Adjutant：Cordate houttuynia 10
G, the g of standard items peppermint oil 10, the g of borneol 5.
The preparation method of the Chinese medicine preparation is as follows：
（1）Decoct for the first time：The g of golden cypress 25, the g of kuh-seng 15, the g of the tuber of stemona 15, the g of the root bark of shaggy-fruited dittany 10, the g of Chinese Fevervine Herb 10, fish are weighed respectively
Raw meat 10 g of grass, extractor is put into, add pure water to 2~3cm of powder is exceeded to extractor, boil by intense fire, then slow fire keeps 25
~35 min, by medical filtration to fluid reservoir, the dregs of a decoction are recycled to extractor；
（2）Second of decoction：Into the dregs of a decoction plus pure water is extremely equal with powder, boils by intense fire, is then cooked by slow fire 25~35 min,
Medical filtration to fluid reservoir, the dregs of a decoction are recycled to extractor again；
（3）Concentration：The decoction for decocting extraction twice is merged, is mixed, is concentrated into paste, obtains Chinese medicine paste；
（4）5 g borneols are weighed, are dissolved in after being milled to powder in 5ml alcohol；
（5）10 g standard items peppermint oils are weighed, together with above-mentioned borneol, Chinese medicine paste, are placed in volume ratio as 1:6 vaseline
With in the mixture of atoleine, wherein vaseline and atoleine mixture is according to mixture:Medicine=20ml:1g addition
Amount addition, and proper amount of surfactant, azone are added, the Chinese medicine preparation is produced after mixing.
Embodiment 2
It is a kind of to treat dog, the Chinese medicine preparation of cat otopathy, it is made up of the following raw material medicine：
Monarch drug in a prescription：The g of golden cypress 15, the g of kuh-seng 30；Ministerial drug：The g of the tuber of stemona 19, the g of the root bark of shaggy-fruited dittany 15, the g of Chinese Fevervine Herb 15；Adjutant：Cordate houttuynia 8
G, the g of standard items peppermint oil 15, the g of borneol 8.
The preparation method of the Chinese medicine preparation is same as Example 1.
Embodiment 3
It is a kind of to treat dog, the Chinese medicine preparation of cat otopathy, it is made up of the following raw material medicine：
Monarch drug in a prescription：The g of golden cypress 30, the g of kuh-seng 20；Ministerial drug：The g of the tuber of stemona 10, the g of the root bark of shaggy-fruited dittany 15, the g of Chinese Fevervine Herb 14；Adjutant：Cordate houttuynia 15
G, the g of standard items peppermint oil 5, the g of borneol 10.
The Chinese medicine preparation is prepared by preparation method same as Example 1.
Chinese medicine preparation prepared by the embodiment of the present invention 1 is used for the treatment of shepherd dog otopathy, and its treatment results is tested
Card, detailed process are as follows：
1）Medicine：The medicine that the medicine that experimental group uses is prepared for the embodiment of the present invention 1, the treatment that control group uses
Medicine is your health, is purchased from Nanjing Golden Shield animal pharmaceutical estate Co., Ltd.
2）Treatment method and result：Choose 600 shepherd dogs for suffering from otopathy（Otitis, ear mite, ear itch）, random point
For eight groups, i.e. experimental group 1 to 4, control group 1 to 4, every group 25, every group sets three repetitions.Control group and experimental group illness shepherd
The administration time of dog, dosage and disease condition are all consistent, specific therapeutic process and treatment results such as table 1 below, table 2.
For identical illness it can be seen from table 1, table 2, in identical medicine dosage, identical treatment time
On, Chinese medicine preparation prepared by the present invention is substantially better than control group in therapeutic effect.
Model case
1. in May, 2016, Guangzhou Ya Ya pet clinics, win U.S. dog within 2 years old, ear itch often rubs table leg, and claw is scratched；Otoscope
Check that ear canal wall is congested, damaged, there is inflammation, secretion microexamination finds there is acarid.
One bottle of the Chinese medicine preparation prepared using the present invention, 2 times a day, one time 2~3 drop, after treating 3 days,
Phone interrogation, symptom have mitigated, and are fully recovered after one week.
2. in August, 2016, Zhumadian post health pets hospital, 3 years old cat one of seeing and treating patients, cardinal symptom is ear itch, ear
Hair comes off, and duct microscopy finds there is inflammation, secretion, is fungal infection by the micro- sem observation of its secretion.Use the present invention
Chinese medicine preparation（Ear relaxes missible oil）One bottle, 2 times a day, one time 2 drop, further consultation after 3 days, symptom substantially mitigates.Then, supplement
Nutrition is continuing with Chinese medicine preparation prepared by the present invention, is fully recovered after one week.
Claims (8)
1. a kind of treat dog, the Chinese medicine preparation of cat otopathy, it is characterised in that is made up of the bulk drug of following parts by weight：Golden cypress 15
~35 parts, 15~30 parts of kuh-seng, 10~20 parts of the tuber of stemona, 5~15 parts of the root bark of shaggy-fruited dittany, 5~15 parts of Chinese Fevervine Herb, cordate houttuynia 5~15
Part, 5~15 parts of peppermint, 3~10 parts of borneol.
2. treatment dog according to claim 1, the Chinese medicine preparation of cat otopathy, it is characterised in that by the raw material of following weight
Medicine is made：25 parts of golden cypress, 15 parts of kuh-seng, 15 parts of the tuber of stemona, 10 parts of the root bark of shaggy-fruited dittany, 10 parts of Chinese Fevervine Herb, 10 parts of cordate houttuynia, peppermint
10 parts, 5 parts of borneol.
3. treatment dog according to claim 1 or 2, the Chinese medicine preparation of cat otopathy, it is characterised in that the peppermint is standard
Savor peppermint oil.
4. treated described in claim 1 dog, cat otopathy Chinese medicine preparation preparation method, it is characterised in that including following step
Suddenly：
（1）Decoct for the first time：Bulk drug golden cypress, kuh-seng, the tuber of stemona, the root bark of shaggy-fruited dittany, Chinese Fevervine Herb, cordate houttuynia are weighed according to the proportioning,
To after itself plus water, boil by intense fire, be then cooked by slow fire 25~35 min, filter to obtain decoction, dregs of a decoction recovery；
（2）Second of decoction：Add water to equal with powder into the recovery dregs of a decoction, boil by intense fire, be then cooked by slow fire 30 min, then
The decoction of filtering；
（3）Concentration：The decoction for decocting extraction twice is merged, paste is concentrated into, obtains Chinese medicine paste；
（4）Borneol is weighed, is dissolved in after being milled to powder in organic solvent；
（5）Peppermint is weighed, the vaseline after mixing is added together with above-mentioned Chinese medicine paste, borneol, in atoleine, and add
Proper amount of surfactant, bleeding agent, mixing.
5. it is according to claim 4 treatment dog, cat otopathy Chinese medicine preparation preparation method, it is characterised in that described
Step（1）In, add and add water to more than the cm of powder 2~3.
6. it is according to claim 4 treatment dog, cat otopathy Chinese medicine preparation preparation method, it is characterised in that in step
（4）In, the organic solvent is alcohol.
7. it is according to claim 4 treatment dog, cat otopathy Chinese medicine preparation preparation method, it is characterised in that in step
（5）In, the vaseline, atoleine are with 1:6 volume ratio mixing.
8. it is according to claim 4 treatment dog, cat otopathy Chinese medicine preparation preparation method, it is characterised in that in step
（5）In, the bleeding agent is azone.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109331134A (en) * | 2018-12-18 | 2019-02-15 | 丹东瑞丰动物药业有限责任公司 | A kind of Chinese medicine and preparation method thereof for treating dog notoedres cati disease |
| CN115177697A (en) * | 2022-07-28 | 2022-10-14 | 殷竹君 | Traditional Chinese medicine preparation for treating intractable otitis media and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101564519A (en) * | 2009-06-05 | 2009-10-28 | 中国人民解放军军事医学科学院军事兽医研究所 | External medicine for treating parasitic infection, fungal infection and bacterial infection of pets and preparation method thereof |
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| 张泉鑫等: "《犬猫疾病 第2版》", 30 June 2007, 北京：中国农业出版社 * |
| 张谦: "动物耳病的病因与临床症状", 《养殖技术顾问》 * |
| 王兆凤,庞华夫: "宠物犬耳病的防治", 《中国畜牧兽医文摘》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109331134A (en) * | 2018-12-18 | 2019-02-15 | 丹东瑞丰动物药业有限责任公司 | A kind of Chinese medicine and preparation method thereof for treating dog notoedres cati disease |
| CN115177697A (en) * | 2022-07-28 | 2022-10-14 | 殷竹君 | Traditional Chinese medicine preparation for treating intractable otitis media and preparation method thereof |
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Application publication date: 20180209 |