CN107580501A - 用于靶向epcam阳性膀胱癌的给药策略 - Google Patents
用于靶向epcam阳性膀胱癌的给药策略 Download PDFInfo
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- CN107580501A CN107580501A CN201680027485.0A CN201680027485A CN107580501A CN 107580501 A CN107580501 A CN 107580501A CN 201680027485 A CN201680027485 A CN 201680027485A CN 107580501 A CN107580501 A CN 107580501A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6861—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from kidney or bladder cancer cell
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- C07K16/3038—Kidney, bladder
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
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- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
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- Immunology (AREA)
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- Molecular Biology (AREA)
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- Toxicology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Inorganic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562132251P | 2015-03-12 | 2015-03-12 | |
| US62/132,251 | 2015-03-12 | ||
| US201562267386P | 2015-12-15 | 2015-12-15 | |
| US62/267,386 | 2015-12-15 | ||
| PCT/US2016/022085 WO2016145354A1 (en) | 2015-03-12 | 2016-03-11 | Dosing strategies for targeting epcam positive bladder cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107580501A true CN107580501A (zh) | 2018-01-12 |
Family
ID=56879327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680027485.0A Pending CN107580501A (zh) | 2015-03-12 | 2016-03-11 | 用于靶向epcam阳性膀胱癌的给药策略 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10583198B2 (enExample) |
| EP (1) | EP3268041A4 (enExample) |
| JP (1) | JP6847846B2 (enExample) |
| CN (1) | CN107580501A (enExample) |
| AU (1) | AU2016228760B2 (enExample) |
| CA (1) | CA2979400A1 (enExample) |
| HK (1) | HK1249731A1 (enExample) |
| WO (1) | WO2016145354A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115109164A (zh) * | 2022-06-07 | 2022-09-27 | 博际生物医药科技(杭州)有限公司 | 靶向epcam和cd3的双特异性抗体 |
| WO2023222024A1 (en) * | 2022-05-18 | 2023-11-23 | Bj Bioscience Inc. | Bispecific antibodies targeting epcam and cd3 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2826735C (en) | 2003-04-30 | 2019-06-04 | University Of Zurich | Methods for treating cancer using an immunotoxin |
| DK3052525T3 (da) | 2013-10-02 | 2019-10-07 | Viventia Bio Inc | Anti-epcam-antistoffer og anvendelsesfremgangsmåder |
| JP6824183B2 (ja) | 2015-03-12 | 2021-02-03 | セセン バイオ,インコーポレイテッド | Epcam陽性膀胱癌の処置方法 |
| AU2016228760B2 (en) | 2015-03-12 | 2020-07-16 | Viventia Bio Inc. | Dosing strategies for targeting EPCAM positive bladder cancer |
| PL3426271T3 (pl) | 2016-03-10 | 2025-11-24 | Cg Oncology, Inc. | Sposoby leczenia guzów litych terapią skojarzoną |
| JP2020516590A (ja) * | 2017-04-14 | 2020-06-11 | コールド ジェネシス, インコーポレイテッド | 膀胱癌の治療方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1816352A (zh) * | 2003-04-30 | 2006-08-09 | 苏黎世大学 | 使用一种免疫毒素治疗癌症的方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5082767A (en) | 1989-02-27 | 1992-01-21 | Hatfield G Wesley | Codon pair utilization |
| IL98528A0 (en) | 1990-06-21 | 1992-07-15 | Merck & Co Inc | Pharmaceutical compositions containing hybrid for killing bladder cancer cells |
| US20030148463A1 (en) | 1997-04-14 | 2003-08-07 | Micromet Ag | Novel method for the production of anti-human antigen receptors and uses thereof |
| GB9709421D0 (en) | 1997-05-10 | 1997-07-02 | Zeneca Ltd | Chemical compounds |
| CA2295189C (en) | 1997-06-06 | 2010-11-23 | Tanox Pharma B.V. | Type-1 ribosome-inactivating protein |
| ATE267215T1 (de) | 1997-12-08 | 2004-06-15 | Lexigen Pharm Corp | Heterodimäre fusionsproteine zur verwendung für gezielte immuntherapie und allgemeine immunerregung |
| US6280742B1 (en) | 1998-06-17 | 2001-08-28 | Zonagen, Inc. | Methods and materials for the treatment of prostatic carcinoma |
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Also Published As
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|---|---|
| AU2016228760B2 (en) | 2020-07-16 |
| US20180104355A1 (en) | 2018-04-19 |
| WO2016145354A1 (en) | 2016-09-15 |
| CA2979400A1 (en) | 2016-09-15 |
| US10583198B2 (en) | 2020-03-10 |
| AU2016228760A1 (en) | 2017-10-05 |
| JP2018512402A (ja) | 2018-05-17 |
| EP3268041A1 (en) | 2018-01-17 |
| EP3268041A4 (en) | 2018-09-05 |
| JP6847846B2 (ja) | 2021-03-24 |
| HK1249731A1 (zh) | 2018-11-09 |
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