CN1075091A - The preparation method of NAOXUESHUAN PIAN - Google Patents
The preparation method of NAOXUESHUAN PIAN Download PDFInfo
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- CN1075091A CN1075091A CN 93110050 CN93110050A CN1075091A CN 1075091 A CN1075091 A CN 1075091A CN 93110050 CN93110050 CN 93110050 CN 93110050 A CN93110050 A CN 93110050A CN 1075091 A CN1075091 A CN 1075091A
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- China
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- preparation
- clear paste
- radix
- hirudo
- paeoniae rubra
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Abstract
A kind of preparation method of NAOXUESHUAN PIAN, its component comprise that Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Persicae, Radix Paeoniae Rubra, Hirudo, Cornu procaprae gutturosae half concentrate powder, artificial Calculus Bovis and Eupolyphaga Seu Steleophaga etc.Preparation method is that Radix Paeoniae Rubra is ground into fine powder, and Flos Carthami and Hirudo are carried out water extraction respectively, is condensed into clear paste; Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Persicae and Eupolyphaga Seu Steleophaga are carried out ethanol extraction; be condensed into clear paste, above-mentioned clear paste is mixed with the Radix Paeoniae Rubra fine powder, add the artificial Calculus Bovis; Cornu procaprae gutturosae half concentrates the powder mix homogeneously; film-making gets final product, and advantage of the present invention is to have stronger anti-thrombosis function, and dose is few; be easy to the patient accepts, preparation method is scientific and reasonable.
Description
The present invention relates to the preparation method of a kind of preparation method of Chinese patent medicine, particularly a kind of NAOXUESHUAN PIAN.
Cerebral thrombosis is old people's a frequently-occurring disease, sufferer serious threat people's physiological function and life, therefore market provides the medicine of various treatment cerebral thrombosiss, the NAOXUESHUAN PIAN of introducing to the market in recent years is the active drug at treatment cerebral thrombosis initial stage, clinical effective rate can reach more than 90%, but orally once reaches seven, has the big shortcoming of dose, like this patient is caused bigger burden, also influence therapeutic effect simultaneously.
The purpose of this invention is to provide a kind of novel NAOXUESHUAN PIAN, taking dose is little, the curative effect height, and the patient is easy to accept, and production technology is reasonable.
The preparation method that the invention provides NAOXUESHUAN PIAN is as follows:
Its prescription:
Each 8-9.5(weight portion of Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Persicae, Radix Paeoniae Rubra and Hirudo), Cornu procaprae gutturosae half concentrates powder, each 1-1.2(weight portion of artificial Calculus Bovis), Eupolyphaga Seu Steleophaga 2-2.3(weight portion).
Preparation method:
Radix Paeoniae Rubra is ground into fine powder; Flos Carthami is carried out water boiling and extraction; be condensed into clear paste; Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Persicae and Eupolyphaga Seu Steleophaga are carried out ethanol extraction, be condensed into clear paste, it is characterized in that: Hirudo is carried out water extraction; the simmer down to clear paste; above-mentioned each clear paste is mixed with the Radix Paeoniae Rubra fine powder, add artificial Calculus Bovis, Cornu procaprae gutturosae half concentrated powder mix homogeneously then, last film-making.
Instructions of taking: oral one time four, every day secondary.
Our experiments show that: compare with NAOXUESHUAN PIAN and existing like products that Hirudo extractum method is made, have stronger anti-thrombosis function, dose reduce near half, alleviate patient's burden, be easy to the patient accepts, production technology is scientific and reasonable.
Provide embodiments of the invention below.
Embodiment 1
It is as follows to write out a prescription: Flos Carthami,, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Persicae, Radix Paeoniae Rubra and each 900g of Hirudo, Cornu procaprae gutturosae half concentrates powder, each 112.5g of artificial Calculus Bovis, Eupolyphaga Seu Steleophaga 225g.
Preparation method: it is standby at first Radix Paeoniae Rubra to be ground into fine powder; Then the Flos Carthami water is decocted, at twice, each 1 hour, fry in shallow oil to such an extent that medicinal liquid merges with twice, be condensed into the clear paste of relative density 1.25; Hirudo is decocted with water three times, and amount of water is followed successively by 6,5,5 times, decocts 2 hours for the first time, is 1.5 hours for the second time, for the third time, fries in shallow oil to such an extent that medicinal liquid merges, filters, is condensed into the clear paste of relative density 1.24 with three times; Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Persicae and Eupolyphaga Seu Steleophaga respectively with 70% ethanol extraction twice, are extracted medicinal liquid with each time and merge, be condensed into the clear paste of relative density 1.25; Three kinds of clear paste are mixed with the Radix Paeoniae Rubra fine powder, add artificial Calculus Bovis, Cornu procaprae gutturosae half then and concentrate the powder mix homogeneously, granulate, dry, be pressed into 5780, sugar coating is promptly.
Embodiment 2
It is as follows to write out a prescription: Flos Carthami,, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Persicae, Radix Paeoniae Rubra and each 925g of Hirudo, Cornu procaprae gutturosae half concentrates powder, each 100g of artificial Calculus Bovis, Eupolyphaga Seu Steleophaga 212.5g.
Preparation method: Flos Carthami is condensed into the clear paste of relative density 1.27 through twice water extraction; Hirudo is condensed into the clear paste of relative density 1.27 through three water extraction; With Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Persicae and Eupolyphaga Seu Steleophaga ethanol extraction twice, be condensed into the clear paste of relative density 1.27, other requires with embodiment 1.
Claims (3)
1, a kind of preparation method of NAOXUESHUAN PIAN, its component comprises Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Persicae, Radix Paeoniae Rubra, Hirudo, Cornu procaprae gutturosae half concentrates powder, artificial Calculus Bovis and Eupolyphaga Seu Steleophaga; Preparation method is: Radix Paeoniae Rubra is ground into fine powder; Flos Carthami is carried out water boiling and extraction; be condensed into clear paste; Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Persicae and Eupolyphaga Seu Steleophaga are carried out ethanol extraction; be condensed into clear paste, it is characterized in that: Hirudo is carried out water extraction, be condensed into clear paste; above-mentioned each clear paste is mixed with the Radix Paeoniae Rubra fine powder, add artificial Calculus Bovis, Cornu procaprae gutturosae half concentrated powder mix homogeneously then.
2, preparation method according to claim 1 is characterized in that: Hirudo carries out water extracting method for decocting with water three times, and amount of water is followed successively by 6,5,5 times, decocts 2 hours for the first time, respectively decocts 1.5 hours for the second time, for the third time.
3, preparation method according to claim 1 is characterized in that: the relative density of Hirudo clear paste is 1.20-1.27.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93110050 CN1075091A (en) | 1993-01-18 | 1993-01-18 | The preparation method of NAOXUESHUAN PIAN |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93110050 CN1075091A (en) | 1993-01-18 | 1993-01-18 | The preparation method of NAOXUESHUAN PIAN |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1075091A true CN1075091A (en) | 1993-08-11 |
Family
ID=4987958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 93110050 Pending CN1075091A (en) | 1993-01-18 | 1993-01-18 | The preparation method of NAOXUESHUAN PIAN |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1075091A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1101692C (en) * | 2000-09-26 | 2003-02-19 | 袁曙光 | Method for preparing Chinese medicine for curing apoplexy and hemiparalysis |
| CN100350928C (en) * | 2005-05-30 | 2007-11-28 | 浙江海正药业股份有限公司 | Cerebral apoplexy treating effervescence tablet and its preparation method |
| CN100350929C (en) * | 2005-05-30 | 2007-11-28 | 浙江海正药业股份有限公司 | Cerebral apoplexy treating dry extract and its preparation process and use |
-
1993
- 1993-01-18 CN CN 93110050 patent/CN1075091A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1101692C (en) * | 2000-09-26 | 2003-02-19 | 袁曙光 | Method for preparing Chinese medicine for curing apoplexy and hemiparalysis |
| CN100350928C (en) * | 2005-05-30 | 2007-11-28 | 浙江海正药业股份有限公司 | Cerebral apoplexy treating effervescence tablet and its preparation method |
| CN100350929C (en) * | 2005-05-30 | 2007-11-28 | 浙江海正药业股份有限公司 | Cerebral apoplexy treating dry extract and its preparation process and use |
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| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |