CN107468595A - A kind of plant bacteriostatic hand sanitizer and preparation method - Google Patents
A kind of plant bacteriostatic hand sanitizer and preparation method Download PDFInfo
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- CN107468595A CN107468595A CN201710905374.1A CN201710905374A CN107468595A CN 107468595 A CN107468595 A CN 107468595A CN 201710905374 A CN201710905374 A CN 201710905374A CN 107468595 A CN107468595 A CN 107468595A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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Abstract
It is as follows comprising main component and mass fraction the invention provides a kind of plant bacteriostatic hand sanitizer：10 40 parts of plant Aqueous extracts, 0.5 5 parts of solubilizer, 10 30 parts of surfactant, 0.5 5 parts of NMF, 0.01 0.8 parts of pH adjusting agents.A kind of plant bacteriostatic hand sanitizer of the present invention, fungistatic effect is good, and moisturizing is moistened after washing.
Description
Technical field
The present invention relates to bacteriostatic hand sanitizer, more particularly to a kind of plant bacteriostatic hand sanitizer and preparation method.
Background technology
At present, as the improvement of people's living standards, people begin to focus on sanitary precaution and maintenance in life.Particularly
For child, sanitary precaution is focused more on.For child, it is usual thing that disease enters from hand.Usually, both hands contact object compares
It is more, so as to increase the chance of contact bacterium, if not washing one's hands, contacting foodstuff, skin are directly removed, some diseases may be caused.This
When, if taking the mode washed one's hands, the antibacterial hand-washing article of energy, such as bacteriostatic hand sanitizer are particularly taken, can greatly be reduced
Bacterium touch opportunity.At present, on the market, hand cleanser that can be antibacterial is fewer, though there is bacteriostatic hand sanitizer, and the artificial conjunction of addition
Into chemical reagent reach fungistatic effect.And artificial synthesized bacteriostatic agent more or less has certain harm to environment.Cause
This, from antibacterial plant, by special processing method, is prepared into fungistatic effect, environment amenable washes one's hands
Liquid, it is necessary.
The content of the invention
Present invention aim to address subproblem present in existing hand cleanser, there is provided a kind of plant bacteriostatic hand sanitizer and
Preparation method.
The purpose of the present invention is achieved through the following technical solutions：
A kind of plant bacteriostatic hand sanitizer, it is as follows comprising main component and mass fraction：
Preferably, it is as follows comprising main component and mass fraction：
Preferably, it is as follows comprising main component and mass fraction：
Preferably, the plant Aqueous extracts are with grass-leaved sweetflag, radix scutellariae, kuh-seng, the fruit of summer cypress, oriental wormwood, cape jasmine, Honeysuckle flower, company
Stick up, snakegourd, aloe, Asian puccoon, ginger, purslane, cordate houttuynia, fevervine, folium sennae, selfheal, at least one of dandelion,
With water example 1 in mass ratio:5-1:1 boil the decoction of water extraction.
Preferably, the solubilizer is selected from least one of Cremophor RH40, nonyl phenol polyethers -14.
Preferably, the surfactant is selected from laureth sodium sulfovinate, laruyl alcohol sodium sulfovinate, coconut oleoyl amine third
Base glycine betaine, lauroylamidopropyl betaine, lauramide both sexes guanidine-acetic acid sodium, coconut oleoyl amine both sexes guanidine-acetic acid sodium, lauroyl
At least one of sodium sarcosinate.
Preferably, the NMF is selected from least one of glycerine, propane diols, butanediol.
Preferably, the preservative is at least one of hydantoins (DMDM), Kathon CG.
Preferably, the chelating agent is disodium ethylene diamine tetraacetate (EDTA-2Na)；Described pH adjusting agent be citric acid,
At least one of acetic acid, lactic acid.
Preferably, also containing deionized water and preservative.
Another aspect of the invention is a kind of preparation method of plant bacteriostatic hand sanitizer, comprise the following steps：
(1) preparation of plant Aqueous extracts：Deionized water and solubilizer are added after dried plant is crushed, soaks 2-3 hours,
After be warming up to 85-95 DEG C, insulation is filtered after boiling 2-3 hours, obtains plant Aqueous extracts；
(2) plant Aqueous extracts, deionized water are placed in main cooker, add chelating agent with 40 revs/min, 5-10 points of stirring
Clock；
(3) surfactant is added, stirs and is warming up to 80-85 DEG C, with 40 revs/min, stirring is to being completely dissolved；
(4) 35-40 DEG C is cooled to, adds NMF, pH value regulator, regulation pH value to 5.5-6.5；
(5) preservative is added, with 40 revs/min, 10-15 minutes is stirred, filters and plant bacteriostatic hand sanitizer is made；
The mass fraction of the main component is as follows：Plant Aqueous extracts：10-40 parts；Solubilizer：0.1-5 parts；Surface-active
Agent：10-30 parts；NMF：0.5-5 parts；PH adjusting agent：0.01-0.8 parts.
Beneficial effects of the present invention：The plant bacteriostatic hand sanitizer of the present invention, it is especially added with the natural plant with fungistatic effect
Thing, it can effectively suppress bacterium.Wherein,
Grass-leaved sweetflag, high concentration leachate have inhibitory action to Common Pathogenic dermatophyte.《Collected statements on the herbal foundation》Record, tool
Control mouth of keeping silent and dislike dysentery；《General Records of Holy Universal Relief》Record to have and control cholera vomiting and diarrhoea incessantly；The also extensive use in various nationalities' medication, such as
《Yunnan medicine record》It is documented in dai medicine " herb controls pruitus "；《Medicine is planted by Yi nationality》Record rhizome treatment chronic bronchitis, suppurative angle
Film is scorching, bacillary dysentery, enteritis.
Radix scutellariae decoction has wider antimicrobial spectrum in vitro, to typhoid bacillus, shigella dysenteriae, Pseudomonas aeruginosa, Bordetella pertussis,
Staphylococcus, streptococcus, Diplococcus pneumopniae, diplococcus meningitidis etc. have inhibitory action.Infected by influenza, Leptospira and
A variety of pathomycetes also have inhibitory action banksia rose streptococcus, it is golden yellow with staphylococcus albus, it is typhoid bacillus, shigella dysenteriae, big
Enterobacteria and a variety of bacterium.《This warp》Main all hot jaundice are recorded, intestines Bleach, profit is let out, relieves oedema or abdominal distension through diuresis or purgation, lower blood closes, (controlling) malignant sore, subcutaneous ulcer erosion, fiery ulcer.
《Japan hanako materia medica》Recording radix scutellariae has lower gas, the main hot disease of day row, furunculosis, apocenosis.Control acute mastitis, carbuncle on the back.《Book on Chinese herbal medicine is just》Record yellow
A kind of reed mentioned in ancient books has dissolving phlegm profit gas, relieving asthma and cough, only loses blood, and moves back alternative fever and chill, and wind-heat is damp and hot, headache, solves pestilence, clearing, treats consumptive lung disease lung carbuncle,
Acute mastitis carbuncle on the back, the heat for fleshy exterior of dispelling especially, therefore control macula, mouse fistula, sore, cute conjunctivitis；The heat of real cool lower Jiao of person, can remove dysentery characterized by blood in the stool, and heat stores wing
Guang, the five puckery pains of leaching, large intestine close knot, have blood in stool, leak blood.《The medicinal herbs among the people of science》Recording radix scutellariae has washout wound, there is anti-corrosion work
With.Modern pharmacology research shows that radix scutellariae has antibacterial action：The concentration of radix scutellariae decoction 100%, flat band method experiment, to shigella dysenteriae,
Typhoid bacillus, paratyphosum Bacterium, comma bacillus, Escherichia coli, proteus, Pseudomonas aeruginosa, staphylococcus, hemolytic vessel used to hold grain at the imperial sacrifice coccus
(a, B), Diplococcus pneumopniae, corynebacterium diphtheriae etc. have inhibitory action.Radix scutellariae decoction test tube method experiment 1：1280 concentration can suppress typhoid fever
Bacillus, hemolytic streptococcus a, 1：640 concentration suppress hemolytic streptococcus B, Diplococcus pneumopniae and shigella flexneri, people's tuberculosis
Bacillus H37,1：320 concentration can suppress comma bacillus, Shigella shigae；1：Sonne bacillus has suppression during 80 concentration
Effect.Radix scutellariae alcohol immersion liquid 0.5g/ml or 0.05g/ml, with agar slant culture, decoction and culture medium 1：1 mixing, to green pus bar
Bacterium has inhibitory action.Radix scutellariae alcohol immersion liquid 2g/ml concentration, Plating are tested to Escherichia coli, tangerine grass bacillus, staphylococcus aureus
There is inhibitory action.Radix scutellariae decoction, alcohol extracting agent 1g/ml concentration, there is suppression effect to meningococcus when being tested with flat band method.Radix scutellariae
There is antifungic action：Radix scutellariae decocting liquid, test tube slant method test 4% concentration and suppress dog denticle born of the same parents bacterium and trichophyton, 8% concentration
Suppress oidium schoenleinii, 10% concentration suppresses the mutation of oidium schoenleinii Mongolia, 15% concentration suppress homocentricity trichophyta and
Rust trichophyta.Radix scutellariae flooding agent 1：3 concentration in vitro to trichophyton, Trichophyton concentricum, oidium schoenleinii,
Microsporon audouini, wool sample microsporum, epidermophyton rubrum, K, W, family name Epidermophyton, star nocardia
Etc. there is different degrees of bacteriostasis.
The decoction of kuh-seng has inhibitory action, right to tubercle bacillus, shigella dysenteriae, staphylococcus aureus, Escherichia coli
A variety of dermatophytes also have inhibitory action.《Haigoushen》Record kuh-seng and " control heat toxin wind, the fidgety raw sore of musculus cutaneus, red leprosy eyebrow takes off, and master removes
Big heat is drowsiness, controls crymodynia in abdomen, middle to dislike stomachache, except body is vexed, controls trusted subordinate's accumulation.”《The southern regions of the Yunnan Province book on Chinese herbal medicine》Recording kuh-seng has " cool blood, solution
Heat toxin, scabies leprosy, impetigo poison.Pruitus is treated, blood wind tinea sore, naughty white bits, discharging fresh blood stool, is had blood in stool.Disappear wind, detumescence poison, phlegm
Poison.”《Tang materia medica》Record and " control shin acid, treat and dislike worm.
The flooding agent (1: 3) of the fruit of summer cypress to oidium schoenleinii, the small gemma tinea bacterium of Du Ang Shi difficult to understand, rust budlet tinea bacterium,
The dermatophytes such as the small gemma tinea bacterium of ulotrichy, star nocardia, there is different degrees of suppression.
Oriental wormwood can suppress a variety of bacillus, coccus effect.《Prescriptions worth thousand gold》Record oriental wormwood and control pruritus life scabies all over：Oriental wormwood is disregarded
How much, boiling down juice washes it.《General Records of Holy Universal Relief》Record oriental wormwood and control wind scabies addiction gizzard, skin is swollen to itch.Modern medicine in vitro test proves, mattress
Old decoction is to staphylococcus aureus, corynebacterium diphtheriae, bacillus anthracis, typhoid bacillus, paratyphoid bacillus A, Pseudomonas aeruginosa, big
Enterobacteria, bacterium flexneri, Shigella shigae, diplococcus meningitidis, hay bacillus etc. have different degrees of suppression to make
With.10% decoction can completely inhibit the growth of Bacillus tuberculosis.1：100 concentration has suppression to human-like with bacillus tuberculosis bovis
Make and use.Capillarisin in vitro test has antagonism to the antibacterial action of chloramphenicol.Capillin has higher resist
Bacterium acts on, and especially to skin pathogenicity der Pilz powerful, shows as bactericidal action, at 100 DEG C of high temperature above of long-time
Reason, its antimicrbial power do not lower still.The growth and breeding of scarlet hair tinea mattress can also be prevented completely under 0.25 μ g/ml concentration.Artemisia scoparia
Lactone has antiinflammatory action to edema caused by mouse carrageenan.Acetic acid writhing test and hot plate method show analgesic activity.
Cape jasmine can suppress staphylococcus aureus and dermatophyte.《Mei Shi collection proved recipes》Record, cape jasmine controls erysipelas poison, pounds
Water dresses it.
Honeysuckle flower has broad-spectrum antibacterial action, can suppress gold containing compositions such as chlorogenic acid, volatile oil, flavonoids, triterpenoid saponins
The multiple pathogenic microorganisms such as the pathogenic bacteria such as staphylococcus aureus, shigella dysenteriae, Leptospira, influenza virus and pathogenic moulds.
The capsule of weeping forsythia has broad-spectrum antibacterial action, have to staphylococcus aureus, Hayes shigella dysenteriae very strong inhibitory action,
Other pathogenic bacteria, influenza virus, fungi can be suppressed.《This warp》The record main fever and chills of the capsule of weeping forsythia, mouse impotence, scrofula, Carbuncle swells dislikes sore, goiter and tumor,
Knot heat.《Jade firewood doctor's order》Record the capsule of weeping forsythia and control the broken raw sore of tongue：The money of the capsule of weeping forsythia five, the money of golden cypress three, the money of radix glycyrrhizae two.Decocting, which contains, gargles.
Research shows snakegourd decoction or preserved material, has suppression to make to the Gram-negative enteral pathogenic bacteria such as Escherichia coli in vitro
With；And to staphylococcus, Diplococcus pneumopniae, α-hemolytic streptococcus, Bacillus influenzae, Microsporon audouini and star
Nocadia etc. also has certain inhibitory action.
Aloe has sterilization antiinflammatory action, can suppress a variety of dermatophytes and Bacillus tuberculosis.《The south of the Five Ridges is gathered medicinal herbs record》Note
Carry aloe stasis eliminatings and dissipate poison：Chinese aloe leaf and salt are mashed, and are applied sore and are worn.
Asian puccoon has inhibitory action to pathogenic microorganisms such as staphylococcus aureus, Escherichia coli, influenza viruses.《Haigoushen》
Record Asian puccoon and " control malignant sore, Guo tinea.”《Detailed outline》Record and " control macula, acne poison, promoting blood circulation and cooling blood, profit large intestine.”
Ginger extract is to staphylococcus aureus, staphylococcus albus, typhoid bacillus, bacterium sonnei, green pus bar
Bacterium has obvious inhibiting effect, and it is acted on concentration in dependence especially with staphylococcus aureus and staphylococcus albus
Inhibitory action is most strong.
The decoction of purslane has inhibitory action to various shigella dysenteriae, typhoid bacillus, staphylococcus aureus in vitro.Horse
Bitterroot is widely used in various nationalities' medication.【Tibetan medicine】,《Chinese Tibetan medicine》Purslane is recorded, herb cures mainly dysentery, red white
Under band, enteritis, gonorrhoea：Furunculosis erysipelas is controlled in external application.【Hani medicine】,《Yunnan medicine record》Record, Portulaca oleracea aerial parts control dysentery, abdomen
Rush down, blood strangury.《Yunnan province will》Record：Complete stool is used to suffer from diarrhoea, dysentery, blood strangury.《Ethnic drug will two》Record herb and cure mainly diarrhoea, dysentery
Disease, blood strangury.【Towards medicine】,《Towards medicine will》Record herb and control clearing heat and detoxicating, quench the thirst, desinsection, for dysentery, all swollen malignant sores, metal-inflicted wound is interior
Fistula.【Maonan's medicine】,《Osmanthus medicine is compiled》Record herb and control dysentery, enteritis, diarrhea.【Seedling medicine】,《Osmanthus medicine is compiled》Record herb and control dysentery, intestines
Inflammation diarrhoea, sore-throat, toothache, nameless sores or boils.《Yunnan medicine record》Record herb and control enteritis, suffer from diarrhoea, dysentery, ephritis, urethral infection
Oedema, canker, hemorrhoid hemorrhage, sore-throat, toothache, nameless sores or boils, ulcerative carbuncle.《Yunnan province will》Record complete stool and be used for urinary tract infection,
Oedema, canker, sore-throat, toothache；It is used for nameless sores or boils outside.【Nahsi medicine】,《Yunnan medicine record》Record herb and control enteritis, dysentery.
【Was's medicine】,《Middle Was's medicine》Record herb and be used for red-white dysentery, bruise blood stasis and swelling pain.【Precious jade medicine】,《Osmanthus medicine is compiled》Record herb and control dysentery
Disease, enteritis, diarrhea, cough with lung heat.《Yunnan province will》Record complete stool and be used for cough with lung heat, ephritis, dysentery, enteritis, hemorrhoid hemorrhage.【Yi nationality
Medicine】,《Osmanthus medicine is compiled》Record herb and control dysentery, fracture.《Dali provides will》Record herb and control dysentery, enteritis, pertussis, pulmonary tuberculosis,
Carbuncle furuncle.【Strong medicine】,《Osmanthus medicine is compiled》Record herb and control dysentery, enteritis, diarrhea, hepatitis, pneumonia, gastrorrhagia, leukorrhea, uterine hemorrhage, malignant boil
Sore, eczema, herpes zoster.【Jingpo medicine】ngimang：Control dysentery, enteritis, mastitis《Dehong medicine is recorded》.【Lisu medicine】Ou Bu Russia：
Herb controls acute gastroenteritis, dysentery, appendicitis, mastitis, hemorrhoid hemorrhage, leukorrhea；Outer treatment sore swells pain, eczema《Nujiang medicine》.
【Dong's medicine】Scold upright stone tablet god：Herb controls dysentery, enteritis, diarrhea, fracture《Osmanthus medicine is compiled》.Upright stone tablet god is scold, scolding must：Herb cures mainly dysentery, enteritis,
Fracture《Ethnic drug will two》.Ma Cha (MalNguedc)：Herb controls bacillary dysentery, diarrhoea, has blood in stool.【Full medicine】Ye Luo gives less, ant dish：
Fresh cauline leaf is cooked for stop dysentery；Raw cauline leaf smashes juice and mixes a little white sugar, mixing in water for oral taking treatment appendicitis, analgesic；Honey is added to boil clothes a little,
Treat pulmonary tuberculosis.
Decanoy acetaldehyde in cordate houttuynia is to staphylococcus aureus, Diplococcus pneumopniae, alpha streptococcus, Bacillus influenzae, card
A variety of Gram-positives and the negative bacterias such as his coccus, typhoid bacillus and tubercle bacillus, there is different degrees of inhibitory action.
《The southern regions of the Yunnan Province book on Chinese herbal medicine》Hemorrhoid can be controlled by recording cordate houttuynia：Cordate houttuynia, decoct soup order watery wine clothes, repeatedly kick into three clothes.Its slag is smoked to be washed, and having purulence, person bursts,
Disappear certainly without purulence person.《Accumulate virtue an Empirical formula》Record cordate houttuynia controls furunculosis and had a pain：Cordate houttuynia mash it is deposited it, pain one, two when, can not go
Grass, pain is latter, is cured within 2nd.
Fevervine can suppress the effect of staphylococcus aureus, shigella flexneri.《Book on Chinese herbal medicine asks former》Record and " it is wet swollen to manage pin
It is rotten, snakebite, beaten with rice and eat and apply ".《The Illustrated Book on Plants》Record and " for wash, removing toxic substances, go wind, heat-clearing, cold dispelling.Apply unknown swollen
Poison, and mend muscles and bones.”
Folium sennae antibacterial action folium sennae immersion liquid has inhibitory action to various bacteria, such as Escherichia coli, proteus, dysentery
Bacillus, alpha streptococcus and Candida albicans and some pathogenic dermatophytes.It is antimycotic：25% flooding agent test tube method, it is right
Microsporon audouini, star-shaped nocardia have inhibitory action.
Selfheal can suppress shigella dysenteriae, typhoid bacillus, comma bacillus, Escherichia coli, Bacillus tuberculosis, grape ball
Bacterium.《Sheng Nong's herbal classic》：" main fever and chills, scrofula, mouse fistula, head sore, break disease.Dissipate goitre knot gas, pin swells arthritis with fixed pain caused by dampness.”《Hygienic easily letter side》Note
Carry selfheal and mash to apply to control to flutter and hinder metal-inflicted wound.Pharmacological action：Decoction, water-leach liquor, alcohol-water leachate and the ethanol of selfheal
Leachate can obviously reduce experimental animal blood pressure, and stem, leaf, fringe and herb have antihypertensive effect, but the effect of fringe is more apparent；Decoct
Agent is in vitro to shigella dysenteriae, typhoid bacillus, comma bacillus, Escherichia coli, proteus, staphylococcus and Bacillus tuberculosis
There is certain inhibitory action.
Dandelion has stronger killing action to staphylococcus aureus, hemolytic streptococcus, to a variety of bacillus, fungi,
Virus has inhibitory action.《Bencao Tujing》：Sore is applied, controls evil thorn and dermatitis contacta again.《Detailed outline is picked up any lost article from the road》：Treat all poisonous insect snakebites.
Also it is widely used in various nationalities' medication.Such as《Cover and plant medicine will》Record dandelion and control acute mastitis, pestilence, lymphnoditis, jaundice,
Bitter taste, thirsty, fever, stomach energy, do not feel like eating, " precious day " disease, food poisoning, old heat.《Seedling medicine》Record herb and control mastitis,
Control scabies.《Yunnan province will》Record and be used for sore carbuncle, venomous snake bite outside dandelion.《Moral dai medicine》Record radix tarxaci and control impetigo.《Soil
Family's medicine》Record herb and control pinkeye, milk carbuncle, lung-fire, sore furuncle poison.
Embodiment
In order to which the present invention is better described, with reference to the embodiment of the present invention, to the technical scheme in the embodiment of the present invention
It is clearly and completely described.
The preparation method of herein described plant bacteriostatic hand sanitizer, comprises the following steps：
1. prepared by plant Aqueous extracts：It will be weighed from the dried plant that pharmacy buys by proportioning, and then crush, add in proportion
Enter deionized water and solubilizer, soak 2 hours, then heat to 85 DEG C, insulation boils 2 hours, then filters, obtains vegetation water
Extract.
2. a certain amount of plant Aqueous extracts, deionized water are placed in main cooker, chelating agent is added with 40 revs/min, stirring 5
Minute.
3. adding load weighted surfactant, 85 DEG C are stirred and are warming up to, with 40 revs/min, stirring is to being completely dissolved.
4. being then cooled between 40 DEG C, NMF is added, adds pH value regulator, regulation pH value to 6.0.
5. adding preservative, with 40 revs/min, stir 10 minutes, filtering and discharging.
Embodiment 1-10 product is prepared using the above method.
Embodiment 1
A kind of plant bacteriostatic hand sanitizer, it is as follows comprising component and mass fraction：
Wherein, plant Aqueous extracts are by grass-leaved sweetflag, radix scutellariae, kuh-seng, the fruit of summer cypress, oriental wormwood, cape jasmine, Honeysuckle flower, the capsule of weeping forsythia, snakegourd
Each 5 parts dry products from pharmacy's purchase, after crushed, (i.e. dried plant powder presses 1 with water with 40 points of water:5) solubilising, is added
0.5 part of agent Cremophor RH40, soak 2 hours, then heat to 85-95 DEG C, insulation boils 2 hours, during which needs slow
Stirring.Then filter, both obtain plant Aqueous extracts.
Embodiment 2
A kind of plant bacteriostatic hand sanitizer, it is as follows comprising component and mass fraction：
Wherein, plant Aqueous extracts be by aloe, Asian puccoon, ginger, purslane, cordate houttuynia, fevervine, folium sennae, selfheal,
Each 5 parts dry products from pharmacy's purchase of dandelion, after crushed, (i.e. dried plant powder presses 1 with water with 60 points of water:1.5),
3 parts of solubilizer nonyl phenol polyethers -14 are added, are soaked 2 hours, then heat to 85-95 DEG C, insulation boils 2 hours, during which need to delay
Slow stirring.Then filter, both obtain plant Aqueous extracts.
Embodiment 3
A kind of plant bacteriostatic hand sanitizer, it is as follows comprising component and mass fraction：
Wherein, plant Aqueous extracts are each by kuh-seng, the fruit of summer cypress, oriental wormwood, cape jasmine, Honeysuckle flower, the capsule of weeping forsythia, snakegourd, aloe, Asian puccoon
5 parts of dry products from pharmacy's purchase, after crushed, (i.e. dried plant powder presses 1 with water with 40 points of water:1) solubilizer, is added
0.5 part of Cremophor RH40, soak 2 hours, then heat to 85-95 DEG C, insulation boils 2 hours, during which need to slowly stir
Mix.Then filter, both obtain plant Aqueous extracts.
Embodiment 4
A kind of plant bacteriostatic hand sanitizer, it is as follows comprising component and mass fraction：
Wherein, plant Aqueous extracts be by aloe, Asian puccoon, ginger, purslane, cordate houttuynia, fevervine, folium sennae, selfheal,
Each 5 parts dry products from pharmacy's purchase of dandelion, after crushed, (i.e. dried plant powder presses 1 with water with 40 points of water:1), add
Enter -14 0.5 parts of solubilizer nonyl phenol polyethers, soak 2 hours, then heat to 85-95 DEG C, insulation boils 2 hours, during which needs
It is slowly stirred.Then filter, both obtain plant Aqueous extracts.
Embodiment 5
A kind of plant bacteriostatic hand sanitizer, it is as follows comprising component and mass fraction：
Wherein, plant Aqueous extracts are each by oriental wormwood, cape jasmine, Honeysuckle flower, the capsule of weeping forsythia, snakegourd, aloe, Asian puccoon, ginger, purslane
5 parts of dry products from pharmacy's purchase, after crushed, (i.e. dried plant powder presses 1 with water with 40 points of water:1) solubilizer, is added
0.5 part of Cremophor RH40, soak 2 hours, then heat to 85-95 DEG C, insulation boils 2 hours, during which need to slowly stir
Mix.Then filter, both obtain plant Aqueous extracts.
Embodiment 6
A kind of plant bacteriostatic hand sanitizer, it is as follows comprising component and mass fraction：
Wherein, plant Aqueous extracts are each by oriental wormwood, cape jasmine, Honeysuckle flower, the capsule of weeping forsythia, snakegourd, aloe, Asian puccoon, ginger, purslane
5 parts of dry products from pharmacy's purchase, after crushed, (i.e. dried plant powder presses 1 with water with 40 points of water:5) solubilizer, is added
0.5 part of Cremophor RH40, soak 2 hours, then heat to 85-95 DEG C, insulation boils 2 hours, during which need to slowly stir
Mix.Then filter, both obtain plant Aqueous extracts.
Embodiment 7
A kind of plant bacteriostatic hand sanitizer, it is as follows comprising component and mass fraction：
Wherein, plant Aqueous extracts are by Honeysuckle flower, the capsule of weeping forsythia, snakegourd, aloe, Asian puccoon, ginger, purslane, cordate houttuynia, chicken arrow
Each 5 parts dry products from pharmacy's purchase of rattan, after crushed, (i.e. dried plant powder presses 1 with water with 40 points of water:3), add and increase
0.5 part of solvent Cremophor RH40, soak 2 hours, then heat to 85-95 DEG C, insulation boils 2 hours, during which need to delay
Slow stirring.Then filter, both obtain plant Aqueous extracts.
Embodiment 8
A kind of plant bacteriostatic hand sanitizer, it is as follows comprising component and mass fraction：
Wherein, plant Aqueous extracts are by grass-leaved sweetflag, kuh-seng, Honeysuckle flower, the capsule of weeping forsythia, snakegourd, Asian puccoon, ginger, cordate houttuynia, Pu Gong
Each 5 parts dry products from pharmacy's purchase of English, after crushed, (i.e. dried plant powder presses 1 with water with 40 points of water:2), add and increase
0.5 part of solvent Cremophor RH40, soak 2 hours, then heat to 85-95 DEG C, insulation boils 2 hours, during which need to delay
Slow stirring.Then filter, both obtain plant Aqueous extracts.
Embodiment 9
A kind of plant bacteriostatic hand sanitizer, it is as follows comprising component and mass fraction：
Wherein, plant Aqueous extracts are by grass-leaved sweetflag, kuh-seng, Honeysuckle flower, the capsule of weeping forsythia, snakegourd, Asian puccoon, ginger, cordate houttuynia, Pu Gong
Each 5 parts dry products from pharmacy's purchase of English, after crushed, (i.e. dried plant powder presses 1 with water with 40 points of water:2), add and increase
0.5 part of solvent Cremophor RH40, soak 2 hours, then heat to 85-95 DEG C, insulation boils 2 hours, during which need to delay
Slow stirring.Then filter, both obtain plant Aqueous extracts.
Embodiment 10
A kind of plant bacteriostatic hand sanitizer, it is as follows comprising component and mass fraction：
Wherein, plant Aqueous extracts are by grass-leaved sweetflag, radix scutellariae, kuh-seng, the fruit of summer cypress, oriental wormwood, cape jasmine, Honeysuckle flower, the capsule of weeping forsythia, Chinese juniper
Each 2.5 parts of building, aloe, Asian puccoon, ginger, purslane, cordate houttuynia, fevervine, folium sennae, selfheal, dandelion is bought from pharmacy
Dry products, after crushed, (i.e. dried plant powder and water press 1 with 55 points of water:1.2) solubilizer PEG-40 hydrogenations, are added
0.5 part of castor oil, soak 2 hours, then heat to 85-95 DEG C, insulation boils 2 hours, during which need to be slowly stirred.Then cross
Filter, both obtain plant Aqueous extracts.
In above-mentioned 10 embodiments, foaming abundancy degree in use is all abundanter than commercially available prod.It is mainly attributed to
Surfactant activity content is high.The fungistatic effect compared with commercially available common non-bacteriostatic hand sanitizer, above-mentioned 10 embodiments have
There is different fungistatic effects, illustrate selected plant, after water extracts, being added in inside hand cleanser has certain antibacterial effect
Fruit.The fungistatic effect compared with commercially available bacteriostatic hand sanitizer, effect is slightly poor, and the bacteriostatic agent for being primarily due to commercially available hand cleanser is artificial
Synthesis, fungistatic effect are efficient.It is antibacterial as traditional draft, there is certain bacteriostasis efficacy still to receive.The product mainly rises
Effect is plant Aqueous extracts, i.e., the effective ingredients in plant extracted by water extraction mode, has in use certain
Fungistatic effect.Bacteriostatic agent is synthesized compared to traditional artificial chemistry, milder is more green.
It is better obvious for embodiment 10 in above-mentioned 10 embodiments, mainly select specific draft to plant
Thing combines, and phase mutual cooperates with antibacterial synergistic effect.Aqueous extracts concentration is high in embodiment 10, and dosage is big.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto,
Any one skilled in the art is in the technical scope of present disclosure, the change or replacement that can readily occur in,
It should all be included within the scope of the present invention.Therefore, protection scope of the present invention should be with the protection of claims
Scope is defined.
Claims (11)
1. a kind of plant bacteriostatic hand sanitizer, it is characterised in that as follows comprising main component and mass fraction：
2. plant bacteriostatic hand sanitizer according to claim 1, it is characterised in that comprising main component and mass fraction such as
Under：
3. plant bacteriostatic hand sanitizer according to claim 1, it is characterised in that comprising main component and mass fraction such as
Under：
4. according to any described plant bacteriostatic hand sanitizers of claim 1-3, it is characterised in that the plant Aqueous extracts are to use stone
Calamus, radix scutellariae, kuh-seng, the fruit of summer cypress, oriental wormwood, cape jasmine, Honeysuckle flower, the capsule of weeping forsythia, snakegourd, aloe, Asian puccoon, ginger, purslane, fish raw meat
At least one of grass, fevervine, folium sennae, selfheal, dandelion, with water example 1 in mass ratio:5-1:1 carries out boiling water extraction
Decoction.
5. according to any described plant bacteriostatic hand sanitizers of claim 1-3, it is characterised in that the solubilizer is selected from PEG-40
At least one of rilanit special, nonyl phenol polyethers -14.
6. according to any described plant bacteriostatic hand sanitizers of claim 1-3, it is characterised in that the surfactant is selected from the moon
Laureth sodium sulfovinate, laruyl alcohol sodium sulfovinate, Cocoamidopropyl betaine, lauroylamidopropyl betaine, lauroyl
At least one of amine both sexes guanidine-acetic acid sodium, coconut oleoyl amine both sexes guanidine-acetic acid sodium, sodium lauroyl sarcosine.
7. according to any described plant bacteriostatic hand sanitizers of claim 1-3, it is characterised in that the NMF be selected from glycerine,
At least one of propane diols, butanediol.
8. according to any described plant bacteriostatic hand sanitizers of claim 1-3, it is characterised in that the preservative is hydantoins
(DMDM), at least one of Kathon CG.
9. according to any described plant bacteriostatic hand sanitizers of claim 1-3, it is characterised in that the chelating agent is ethylenediamine tetraacetic
Acetic acid disodium (EDTA-2Na)；Described pH adjusting agent is at least one of citric acid, acetic acid, lactic acid.
10. according to any described plant bacteriostatic hand sanitizers of claim 1-3, it is characterised in that also containing deionized water and prevent
Rotten agent.
11. a kind of preparation method of plant bacteriostatic hand sanitizer, it is characterised in that comprise the following steps：
(1) preparation of plant Aqueous extracts：Deionized water and solubilizer are added after dried plant is crushed, is soaked 2-3 hours, it is rear to rise
Temperature to 85-95 DEG C, after boiling 2-3 hours filter, and obtains plant Aqueous extracts by insulation；
(2) plant Aqueous extracts, deionized water are placed in main cooker, add chelating agent with 40 revs/min, stir 5-10 minutes；
(3) surfactant is added, stirs and is warming up to 80-85 DEG C, with 40 revs/min, stirring is to being completely dissolved；
(4) 35-40 DEG C is cooled to, adds NMF, pH value regulator, regulation pH value to 5.5-6.5；
(5) preservative is added, with 40 revs/min, 10-15 minutes is stirred, filters and plant bacteriostatic hand sanitizer is made；
The mass fraction of the main component is as follows：Plant Aqueous extracts：10-40 parts；Solubilizer：0.1-5 parts；Surfactant：
10-30 parts；NMF：0.5-5 parts；PH adjusting agent：0.01-0.8 parts.
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| CN107854370A (en) * | 2017-12-25 | 2018-03-30 | 芜湖皖江知识产权运营中心有限公司 | A kind of antibacterial delicate fragrance type hand cleanser and preparation method thereof |
| CN108308203A (en) * | 2018-01-31 | 2018-07-24 | 南京紫源康医药科技有限公司 | A kind of preparation method of Chinese medicinal compound extract, extract and bacteria inhibiting composition |
| CN108324677A (en) * | 2018-05-16 | 2018-07-27 | 浙江艳庄化妆品有限公司 | A kind of vanishing cream for being suitable for sensitive skin crowd and using |
| CN109055058A (en) * | 2018-08-24 | 2018-12-21 | 中山市洁莹生物科技有限公司 | A kind of plant bacteriostatic hand sanitizer and preparation method thereof |
| CN109276499A (en) * | 2018-11-14 | 2019-01-29 | 浙江海洋大学 | A kind of the natural plants hand cleanser and preparation method of preservative free |
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| CN108308203A (en) * | 2018-01-31 | 2018-07-24 | 南京紫源康医药科技有限公司 | A kind of preparation method of Chinese medicinal compound extract, extract and bacteria inhibiting composition |
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| CN108324677B (en) * | 2018-05-16 | 2019-09-10 | 浙江艳庄化妆品有限公司 | A kind of vanishing cream used suitable for sensitive skin crowd |
| CN109055058A (en) * | 2018-08-24 | 2018-12-21 | 中山市洁莹生物科技有限公司 | A kind of plant bacteriostatic hand sanitizer and preparation method thereof |
| CN109276499A (en) * | 2018-11-14 | 2019-01-29 | 浙江海洋大学 | A kind of the natural plants hand cleanser and preparation method of preservative free |
| CN111202770A (en) * | 2018-11-22 | 2020-05-29 | 深圳波顿香料有限公司 | Antibacterial Chinese herbal medicine compound preparation, preparation method and hand sanitizer |
| CN111450019A (en) * | 2020-04-21 | 2020-07-28 | 恒创化学科技(常州)有限公司 | Antibacterial no-wash hand sanitizer and preparation method thereof |
| CN111467288A (en) * | 2020-05-25 | 2020-07-31 | 四川涑爽医疗用品有限公司 | Hand-washing-free disinfectant and preparation method thereof |
| CN111603422A (en) * | 2020-06-23 | 2020-09-01 | 广州市华晟健康产业有限公司 | Silver ion antibacterial hand sanitizer and preparation method and application thereof |
| KR102251911B1 (en) * | 2020-06-23 | 2021-05-12 | 로우비 (광저우) 헬스 인더스트리 컴퍼니 리미티드 | Silver ion bacteriostatic hand sanitizer and preparation method and application thereof |
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| WO2021258654A1 (en) * | 2020-06-23 | 2021-12-30 | 广州市华晟健康产业有限公司 | Silver ion antibacterial hand sanitizer, preparation method therefor, and application thereof |
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Application publication date: 20171215 |