CN103689010B - Medicine for hog house disinfection - Google Patents
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Abstract
The technical problem to be solved in the present invention is to provide a kind of medicine aiming at hog house disinfection.Adopt this Chinese medicine composition to have pig farm sterilization and the prevention of disease to draw materials conveniently, without poisoning, cost is low, and meat is without the advantage such as sorrow of commodity inspection.In order to solve the problems of the technologies described above, the invention provides a kind of medicine of hog house disinfection, it comprises: azedarach, camphortree leaf, myrrh, climbing groundsel, Lygodium japonicum, goldenrod, frankincense, honeysuckle, peppermint, orange peel, moutan bark, Chinese tuliptree bark, dandelion, denseflower indigo leaf, Lappula echinata and grassleaf sweetflag leaf, amounts to 16 taste Chinese medicinal herbses.
Description
Technical field
The present invention relates to the field of Chinese medicines, specifically a kind of medicine for hog house disinfection.
Background technology
Current piggery major part is all using lime as disinfectant.But there are many professional raising farmer usings method improper, cause Disinfection Effect bad.Specialist, in order to follow the line of least resistance, disposablely buys much quicklime, once cannots be used up, and continues to be used as to sterilize later.This is incorrect, because quicklime chemical name is in calcium oxide, namely generates loose white lime after adding water, if quicklime is placed in the container of sealing, also moisture in air can be absorbed, age lime, i.e. slaked lime, the hydroxide ion only having this dissociation to go out just has bactericidal action.If white lime is put of long duration, with the carbonic acid gas chemically reactive in air, the calcium carbonate not having hydroxide ion will be generated, completely lost the effect of sterilizing.If fresh white lime, certain Disinfection Effect can be played.If infrequently change fresh white lime, and clothes, instrument etc. are not sterilized and still germ, virus can be brought in mew.If white lime is directly sprinkling upon in mew on ground, easily by the limb hoof of pig and skin burn, or to eat food the food (being stained with white lime) and burn oral cavity and digestive tract fallen to the ground because of pig.Lime dust can be caused when liming powder in addition to fly upward in a large number, pig is sucked in respiratory tract, the respiratory symptom such as cause cough, sneeze.
Raise pigs on a large scale, easily grow a lot of germ, in line with the principle being conducive to epidemic preventing sanitary, completely inadequate to the cleaning cleaning of pig house every day, it is indispensable for being equipped with disinfection apparatus management, disinfection is the problem that each pig farm be everybody knows, but is having a lot of raiser to think little of sterilization; Or do not know how to go sterilization, look on the surface and sterilized, in fact do not reach the object of sterilization.
The sterilization of pig house is different with extraneous sterilization, and because place does not have ight soil, pig house has the residues such as the anxious afterbirth of a large amount of fecalurias.And ight soil is can not being interrupted of constantly discharging, so thorough disinfection pig house need produce pig house pig, hog house disinfection generally on every Mondays to twice, at least one times.About the use of thimerosal, some people thinks that concentration is the bigger the better, so in real work, the concentration of groups of people's proportioning, exceeds the ratio of explanation; Or some people is in order to save, the concentration of proportioning is less than the concentration on specification, and these are all wrong.
Summary of the invention
For the problems referred to above, the technical problem to be solved in the present invention is to provide a kind of medicine aiming at hog house disinfection.Adopt this Chinese medicine composition to have pig farm sterilization and the prevention of disease to draw materials conveniently, without poisoning, cost is low, and meat is without the advantage such as sorrow of commodity inspection.
In order to solve the problems of the technologies described above, the invention provides a kind of medicine of hog house disinfection, it comprises: azedarach, camphortree leaf, myrrh, climbing groundsel, Lygodium japonicum, goldenrod, frankincense, honeysuckle, peppermint, orange peel, moutan bark, Chinese tuliptree bark, dandelion, denseflower indigo leaf, Lappula echinata and grassleaf sweetflag leaf, amounts to 16 taste Chinese medicinal herbses.
Wherein, the ratio of weight and number of each component in described medicine is, described azedarach 50 ~ 60 weight portion, described camphortree leaf 30 ~ 35 weight portion, described myrrh 15 ~ 20 weight portion, described climbing groundsel 15 ~ 20 weight portion, described Lygodium japonicum 15 ~ 20 weight portion, described goldenrod 10 ~ 15 weight portion, described frankincense 20 ~ 25 weight portion, described honeysuckle 10 ~ 15 weight portion, described peppermint 10 ~ 15 weight portion, described orange peel 20 ~ 25 weight portion, described moutan bark 10 ~ 15 weight portion, described Chinese tuliptree bark 20 ~ 25 weight portion, described dandelion 20 ~ 25 weight portion, described denseflower indigo leaf 20 ~ 25 weight portion, described Lappula echinata 10 ~ 15 weight portion and described grassleaf sweetflag leaf 15 ~ 20 weight portion.
For solving the problems of the technologies described above, present invention also offers a kind of medicine for hog house disinfection, described medicine is prepared from by the following method:
The first step, loads azedarach, myrrh, Lappula echinata, orange peel, moutan bark, Chinese tuliptree bark in multi-function extractor, adds alcohol heating reflux and extracts, merge extract, centrifugal, filter, obtain filtered fluid, reduced pressure concentration reclaims ethanol, obtain medicinal extract, by medicinal extract stored refrigerated, enter in spray dryer dry subsequently, pulverize with cracker and sieve, obtaining granularity is 50 ~ 100 object powder;
Second step, will remain herbal raw material difference boiling 2 ~ 4 times, merge respective decoction liquor, filter, left undisturbed overnight, extract supernatant, reduced pressure concentration, except anhydrating, is dried to dry cream respectively, pulverizes and sieves, and obtains 70 ~ 120 order powder;
3rd step, drops into above-mentioned powder in agitator during use and is stirred to evenly under normal temperature and pressure conditions, be added in warm water and obtain described disinfection of Chinese drug medicine.
The pig house cleaned out and pig, can use medicine of the present invention directly to spray, rinse or spread upon on pig house and porcine skin, not only sterilizing, prevent disease, also has the effect repelled mosquitoes and flies with deodorizing.
Wherein, the ratio of described medicine and warm water is 1:10.
As preferably, can also add acetic acid ratio in described medicine is 1:10.
As preferably, sulphanilamide crystal powder 10 ~ 15 weight portion in described medicine, can also be added.
Beneficial effect of the present invention:
Relative to of the prior art for disinfection and prophylactic sterilization method, the present invention adopts this Chinese medicine composition to have remarkable result to disinfection and prevent disease, and the present invention draws materials conveniently, and safety is without poisoning, cost is low, and meat is without the advantage such as sorrow of commodity inspection.
the pharmacology and the property of medicine that the present invention relates to Chinese medicine material are as follows:
Azedarach:
Not [nature and flavor] " not Lu ": " be slightly cold." " Japan hanako materia medica ": " is bitter, micro-poison." " medical center nationality is wanted ": " is bitter greatly, Great Cold."
[function cures mainly] heat-clearing, eliminating dampness, desinsection.Control roundworm, pinworm, rubella, mange.
[pharmacological action] 1, anthelmintic action: show through pig test, this medicine decoction or alcohol extract all have suppression so that paralysis effect to ascaris suum.The active ingredient of driving ascarid effect is toosendanin, stronger than the effect of ethanol extract.The toosendanin of low concentration (1:5000-9000), obvious excitation is had to whole piece ascaris suum and sections (head and middle part) thereof, show as spontaneous activity to strengthen, there is abnormal violent contraction off and on, destroy its laws of motion (movable strengthen with weaken alternate), continue 10-24 hour, finally proceed to spasmodic contraction gradually.Toosendanin through polypide epidermis, can directly act on Ascaris Suum muscle, upsets its energy metabolism, causes contraction fatigue and spasm.The melia toosendan rope of this concentration to the excitation of roundworm neuro-muscular not block by atropine, prompting toosendanin is not cholinomimetic.The toosendanin of high concentration (l:1000) neuromere to ascaris suum particularly head has paralysis effect.This paralysis effect may be the result of shrinking in intermittent cramp after polypide is subject to drug effect.Measure the cholinesterase activity of polypide homogenate respectively through Ammon method and Warburg apparatus and breathe glycolysis, result proves all to have no significant effect, and shows that toosendanin is not worked by glycometabolism.Separately as can be seen from the experimental result of the ATP in Ascaris Suum muscle and Phos, toosendanin can make the katabolism of ATP accelerate, thus causes roundworm have energy short supply and cause fatigue of contraction, and is excreted.The azedarach liquid (25%-50%) of high concentration also has paralysis effect to mouse pinworm in vitro.2, on the impact of respiratory center: heavy dose of toosendanin (every rat, vein or intramuscular injection 2mg) can cause rats breathing exhaustion.This is mainly because this composition is to the inhibitory action of maincenter.Medulla oblongata respiratory center position directly gives toosendanin (every rat 0.10-0.15mg), can support the above results.Central stimulant nikethamidum has slight antagonism to the respiration inhibition that toosendanin causes.3, on the impact of Neuromuscular Transmission Function: toosendanin has the contraction of muscle irreversibly checking indirect stimulation and cause to rat, but the excitatory transmission do not affected the nerves, do not reduce muscle to the reaction directly stimulated yet; Toosendanin is 1 and optionally acts on presynaptic Phrenic nerve diaphragm blocking agent.Its site of action is at presynaptic nerve teminal, and the mode of action suppresses the acetylcholine release brought out of exciting nerve.Electron microscope observation shows that the submicroscopic structure of toosendanin to small white mouse neuromuscular junction has obvious effect, shows that synaptic cleft width increases and synaptic vesicle decreased number.These two kinds changes appear at same joint time different.4, anti-botulismus: toosendanin has therapeutic action to botulismus animal.To the mouse of lethal dose A type botulismus, within poisoning latter 6 hours, give toosendanin, have obvious therapeutic action; To the monkey of lethal dose A type botulismus, within poisoning latter 24 hours, give toosendanin, animal more than half can be cured; To the mouse of Type B botulismus, toosendanin also has protective effect.In addition, toosendanin obviously can strengthen the therapeutic action of antitoxic serum to botulismus white mice and rabbits.5, on the impact of heart nipple myoelectricity and mechanical property: make the time-histories (APD90) of fast response current potential multipole to 90% extend chinaberry element concentration dependent, Ik1 is blocked with barium chloride, the effect that toosendanin extends APD90 can be cancelled, long response time electricity e Huai Pian PD is extended toosendanin and convergent force (FC) strengthens, after barium chloride, can cancel the above-mentioned effect of toosendanin, but the effect extending APD exists.In addition, toosendanin can make isolated frog heart shrink allorhythmic pulse, continues can automatically recover for l hour.6, other effects: chinaberry element (200mg/kg) rabbit gavage and concentration are 0.2 × 10(-4) toosendanin of mg all has remarkable increase to the tension force of rabbit in place and isolated rabbit intestines and convergent force.Concentration is 0.2 × l0(-3) toosendanin of mg can make myenteron present spasmodic contraction.This excitation can resist by diphenhydramine, and not block by atropine.10% azedarach infusion has inhibitory action to multiple pathogenic fungus.Melia extract for treating mouse experiment Manson's schistosomiasis, confirms there is certain curative effect from the animal body internal memory aspect such as borer population and hatching test alive.
Camphortree leaf:
[nature and flavor] " Luchuan book on Chinese herbal medicine ": " bitter is pungent, temperature."
[function cures mainly] dispels the wind, dehumidifying, pain relieving, desinsection.Control treating rheumatic ostealgia, traumatic injury, mange.
Myrrh:
[nature and flavor] are bitter, pungent, flat.
[function] is antibacterial, antimicrobial, anti-inflammatory, convergence, tool balosam speciality, deodorizing, ventosity of dispelling, sterilization, diuresis, stimulate the menstrual flow, reduce phlegm, killing fungus, excitation, sharp stomach, urge sweat, mend body, sharp uterus, control wound, to ripe dry and cracked to take off coarse skin helpful.
Climbing groundsel:
[meridian distribution of property and flavor] is bitter, sweet, cold, pungent, cool.Nontoxic.
[function cures mainly] is clearing heat and detoxicating, desinsection, improving eyesight.Modern pharmacological research: 1, antibacterial action, has stronger antibacterial action to Shigella shigae, staphylococcus aureus, cured sample bacillus anthracis.2, anti-conveyor screw effect.3, Trichomonas vaginalis effect is suppressed." Chinese medicine voluminous dictionary " report is used for the treatment of: various diseases associated with inflammation scabies impetigo poison, eczema, Trichomonas vaginalis, various vaginitis, cervicitis, ulcer, hemorrhoid etc.
Lygodium japonicum:
[nature and flavor] are cold in nature, and taste is sweet.Return bladder, small intestinl channel;
[function] has antibacterial, diuresis, for the infection of the upper respiratory tract, mumps, urinary tract infections etc.
Goldenrod:
[meridian distribution of property and flavor] is pungent, bitter, flat.Enter liver, courage two warp.
[function] wind and heat dispersing, anti-inflammation.For anemopyretic cold headache, (chill is avoided) is clearing heat and detoxicating, and detumescence is except pain.The infection of the upper respiratory tract, tonsillitis, abscess of throat, bronchitis, pneumonia, pulmonary tuberculosis hemoptysis, anxious, chronic nephritis, infantile malnutrition, traumatic injury is controlled in external application, venomous snake bite, sore swollen toxin, mastitis, 1, antibacterial action: decoction (causes inflammation of suppurating to staphylococcus aureus in vitro, skin scabies carbuncle, infant bronchitis), Pseudomonas aeruginosa (pneumonia), dysentery (acute bacillary dysentery), (enteron aisle injures typhoid bacillus, avoid and be cautious use of for a long time, easily hemorrhage), Diplococcus pneumopniae (lobar pneumonia), α-hemolytic streptococcus (tonsillitis) and red moss bacterium, Candida albicans (belongs to fungi and causes the fungal infection of the hand, onychomycosis, the ringworm of the foot, women's colpomycosis) all there is inhibitory action.
Honeysuckle:
[nature and flavor] property is sweet, cold;
[function] has heat-clearing, removing toxic substances, anti-inflammatory, antibacterial effect.Compendium of Material Medica is carried " honeysuckle, being good at poison, therefore control ulcer, pyogenic infections, sore tinea ... ".Since ancient times, honeysuckle is usually used in clearing heat and detoxicating, the heating for the treatment of warm disease, toxic-heat and blood stasis, the diseases such as large carbuncle, also for anemopyretic cold, and the illnesss such as bronchitis.Modern pharmacological research shows, honeysuckle has the effects such as antibacterial, antiviral, anti-inflammatory, antipyretic, immunity moderation.
The loose poison of heat-clearing, Compendium of Material Medica is carried " honeysuckle, being good at poison, therefore control ulcer, pyogenic infections, sore tinea ... ".Since ancient times, honeysuckle is usually used in clearing heat and detoxicating, the heating for the treatment of warm disease, toxic-heat and blood stasis, the diseases such as large carbuncle.Modern pharmacological research shows, honeysuckle has the effect traditional Chinese medical science such as antibacterial, antiviral, anti-inflammatory, antipyretic, immunity moderation and thinks, honeysuckle is cold in nature, taste is sweet, gas is flat, has clearing heat and detoxicating effect, can treat the diseases such as hot malicious early stage of pyogenic infection of skin, ulcer furunculosis.And have the loose effect of a surname concurrently.Honeysuckle antipyretic and antidote functions is quite strong.Honeysuckle can delay the pathology effect of Respirovirus to cell, is clearing heat and detoxicating representative medicine, and hot malicious essence is except containing multiple pathogenic microorganisms, and microbial toxin also accounts for critical positions.Caused by the endotoxin that honeysuckle preparation lumbar injection obviously can reduce Pseudomonas aeruginosa, the leukocyte count of rabbit declines, and deviation to the left phenomenon etc. has obvious antagonism.The honeysuckle compatibility root of large-flowered skullcap is prepared into poisoning symptom and the death that preparation obviously can alleviate Pseudomonas aeruginosa endotoxin caused rabbit.
Peppermint:
[meridian distribution of property and flavor] is cool in nature, taste is pungent;
The effect of [function] anti-irritant causes tracheae to produce new secretion, and makes the mucus of stiff be easy to get rid of, thus have eliminate the phlegm, the effect of sterilization.
It is one of Chinese conventional Chinese medicine.It is pungent cool property sweating antipyretic medicine, controls influenza, the disease such as headache, hot eyes, body heat, throat, gum swell and ache.Place is with controlling neuralgia, pruitus, fash and eczema etc.The peppermint of light friend Greenhouse Fruit Picking is again the fresh vegetable on dining table in the Spring Festival.Clearly good to eat.Usually with peppermint for tea, clear away heart-fire improving eyesight.Peppermint has extremely strong sterilization antibacterial action, often drinks its energy preventing viral flu, mouth disease, makes breath freshening.Gargle with mint tea juice, can be anti-halitosis in advance.Steam face with mint tea mist, also have the effect of shrinking pore.Apply by the blade steeping tea and can feel refrigerant on eyes, can eye fatigue be removed.It is said and can be used for the another name that peppermint also has " eyes grass " treating eye illness.
Orange peel:
Orange peel, gives out golden yellow clear bright pericarp, except fragrant sour-sweet taste, also has one simple and elegant flowery odour, can promote appetite, skin maintenance, minimizing sense of fatigue.Sweet strongly fragrant fruital, is applicable to drinking together with other flowers and plants very much.
Citrus is nutritious and one of maximum fruit of consumption figure.Pulp flavor is splendid, and juice sweet taste is beautiful, also often makes popular drink.Can be made into candy and jelly etc. after orange peel processing, is the traditional Chinese medical science conventional " dried orange peel " after drying; Blade, flower and fruit can refine essential oil, perfume.Pomace and pericarp also can obtain through refining pectin and aromatic oil orange peel brews up, and regulates the flow of vital energy, effect of stopping coughing and removing phlegm during orange peel can be utilized wide, and orange peel bubble green tea, can reduce phlegm and internal heat and separate phlegm, anti-inflammation, therefore cough ant phlegm person drink is useful.
Moutan bark: tree peony not only has ornamental value, but also there is very high medical value.Being processed into " root bark of tree peony " by the root of tree peony, is famous and precious Chinese herbal medicine.Its cold nature, taste is pungent, nontoxic, enter the heart, liver, kidney three warp, have loose hemostasis, purify the blood and blood, pain relieving, the effect of stimulating the menstrual flow, reduce blood pressure in addition, effect of anti-inflammation, clothes can be lengthened the life by beneficial body for a long time.Nourish blood and liver, the loose strongly fragrant stasis of blood of dispelling, be applicable to chloasma faciei, skin senescence, normal drink qi and blood is lived lung, and appearance is ruddy, improves menstrual disorder, dysmenorrhoea, only abnormal sweating, night sweat.
Chinese tuliptree bark:
[nature and flavor] are pungent; Warm in nature
[function cures mainly] dispels rheumatism; Loose cold cough-relieving.Main air pain of dampness syndrome; Cough due to wind-cold evil
[usage and dosage] takes orally: decoct soup, 9 ~ 15g.
[1]
Pharmacological action
Antibacterial action heartwood ethanol extract has antibacterial action, effective to staphylococcus aureus, M. smegmatis, Candida albicans and aspergillus niger etc., proves that antibiotic effective ingredient is dehydroglaucin (dehydroglaucine) further.
Denseflower indigo leaf:
[meridian distribution of property and flavor] taste is pungent; Bitter; Warm in nature.
[function cures mainly] desinsection; The antipruritic ringworm of the foot; Scabies.
Lappula echinata:
[meridian distribution of property and flavor] toil, flat, poisonous.1. Tang Materia Medica: " bitter, flat, slightly poisonous." 2. " detailed outline ": " and toil, slightly poisonous." 3. " medical center bun is wanted ": " toil, temperature." enter spleen, stomach, Liver Channel; " herbal classic is met former " " " enter to faint cloudy Liver Channel.”
[effect] desinsection, clearing heat and detoxicating, strengthening the spleen and stomach.
[curing mainly] controls abdominal pain due to enterositosis, Trichomonas vaginalis; It has anthelmintic action, and 1% Lappula echinata is joined in 5 dropping human physiology saline solution 25ml, 37 DEG CZai Fang National People's Congress tapeworms of heating, and result 1-2 minute namely dead.
Grassleaf sweetflag leaf:
[nature and flavor] are pungent, temperature enters the heart, lung two warp.
[function cures mainly] detoxification sore treatment, desinsection.Control sore scabies, leprosy, impetigo.
embodiment:
Embodiment 1, formula: described azedarach 50g, described camphortree leaf 30g, described myrrh 15g, described climbing groundsel 15g, described Lygodium japonicum 15g, described goldenrod 10g, described frankincense 20g, described honeysuckle 10g, described peppermint 10g, described orange peel 20g, described moutan bark 10g, described Chinese tuliptree bark 20g, described dandelion 20g, described denseflower indigo leaf 20g, described Lappula echinata 10g and described grassleaf sweetflag leaf 15g.
Preparation process is as follows:
The first step, loads azedarach, myrrh, Lappula echinata, orange peel, moutan bark, Chinese tuliptree bark in multi-function extractor, adds alcohol heating reflux and extracts, merge extract, centrifugal, filter, obtain filtered fluid, reduced pressure concentration reclaims ethanol, obtain medicinal extract, by medicinal extract stored refrigerated, enter in spray dryer dry subsequently, pulverize with cracker and sieve, obtaining granularity is 50 ~ 100 object powder;
Second step, will remain herbal raw material difference boiling 2 ~ 4 times, merge respective decoction liquor, filter, left undisturbed overnight, extract supernatant, reduced pressure concentration, except anhydrating, is dried to dry cream respectively, pulverizes and sieves, and obtains 70 ~ 120 order powder;
3rd step, drops into above-mentioned powder in agitator during use and is stirred to evenly under normal temperature and pressure conditions, be added in warm water and obtain described disinfection of Chinese drug medicine.
The pig house cleaned out and pig, can use medicine of the present invention directly to spray, rinse or spread upon on pig house and porcine skin, not only sterilizing, prevent disease, also has the effect repelled mosquitoes and flies with deodorizing.
Wherein, the ratio of described medicine and warm water is 1:10.
As preferably, can also add acetic acid ratio in described medicine is 1:10.
As preferably, sulphanilamide crystal powder 10g in described medicine, can also be added.
Embodiments of the invention 1 medicine is to the acute toxicity experience of mouse
1. experimental animal
The healthy KM mouse of SPF level, 30, male and female half and half, body weight 20-25g; Purchased from scientific tcm institute of Shandong Province Experimental Animal Center
2. detect reagent serum AST, ALT detection kit purchased from Beijing Zhong Sheng company
3. checkout equipment
Micro-200 semiautomatic biochemistry detector, analytical balance, disscting instrument, syringe, test tube etc.
4. test method
After the adaptability of 3 days are raised, be divided at random 5 groups (male and female half and half), often organize each 10; Control group, 4 various dose groups (be only respectively 76mg/, only, only, 357.6mg/ only for 219.9mg/ for 152.1mg/).Mouse free choice feeding, drinking-water, in feeding process, every day changes water, the next day change bedding and padding.Whole experimental period is 7 days.
5. testing index and method
(1) clinicing symptom observation: every day viewing test mouse the state of mind, diet situation, every day entry morbidity death condition.
(2) pathological observation: dead mouse is carried out cuing open inspection and observes internal organ change.
(3) growth indexes is observed: carry out routine weighing to test mouse; Off-test, slaughters that mouse weighs in, the heavy organ index of internal organs measures: cut open inspection kunming mice, core dirty, spleen, liver, kidney, testis, ovary, weigh, calculate organ index according to the following formula: organ index=internal organs weight/body weight × 100.
(4) liver function change is observed: after off-test, slaughter mouse, take blood separation of serum, measures AST, ALT.
6. data processing: above data acquisition SPSS11.0 carries out analytic statistics.
Clinicing symptom observation
Experimental group mouse, the state of mind and diet wish, to external world respond have no obvious exception.Each group of mouse morbidity and death condition are as following table 1.
Table 1
Pathological observation: experimental group, mouse carries out cuing open inspection and observes to have no and observe the obvious pathological change of internal organs after slaughtering.
Growth indexes is observed: off-test, slaughters that mouse weighs in, internal organs weight analysis is in table 2.
Table 2
Liver function change is observed
After off-test, slaughter mouse, take blood separation of serum, measure AST, ALT in table 3.It is not remarkable that result shows each group of data difference compared with normal healthy controls group, is all in normal range (NR).
Table 3
Even if prove that the present invention all has no adverse reaction for the animal drunk or eat medicine of the present invention by mistake by mistake by upper experiment.
Clinical trial
By 480 health pig (male and female half and half, body weight is between 150kg ~ 200kg) be divided into two groups at random, group I is that pig house uses disinfection apparatus and control group after using herbal sprinkling of the present invention, group II be the pig house method that uses disinfection apparatus and disinfection tool also to use to lime as a control group.
Each group of pig free choice feeding, drinking-water, Routine Management; Raise identical number of days, pig symptom is observed during 9:00 and 16:00 every day, dead pig is weighed, anatomic observation pathological change, and perform detailed record, carry out weighing to not dead pig, dissecting for ten days to test, and recorded pathology situation, after having tested, data statistics is carried out to sick/dead rate of test, sick pig rate=sick pig number ÷ pig sum.Concrete outcome is in table 4.
Table 4
| Pig number | Sick pig number | Sick pig rate % | |
| Group I | 240 | 0 | 0 |
| Group II | 240 | 15 | 6.25% |
Embodiment 2, formula:
Described azedarach 60g, described camphortree leaf 35g, described myrrh 20g, described climbing groundsel 20g, described Lygodium japonicum 20g, described goldenrod 15g, described frankincense 25g, described honeysuckle 15g, described peppermint 15g, described orange peel 25g, described moutan bark 15g, described Chinese tuliptree bark 25g, described dandelion 25g, described denseflower indigo leaf 25g, described Lappula echinata 15g and described grassleaf sweetflag leaf 20g;
Preparation method's using method is identical with embodiment 1.
Embodiments of the invention 2 medicine is to the acute toxicity experience of mouse
Test method is identical with the test method of embodiment 1,
Even if experiment proves that the present invention all has no adverse reaction for the animal drunk or eat medicine of the present invention by mistake by mistake.
Clinical trial
By 480 health pig (male and female half and half, body weight is between 150kg ~ 200kg) be divided into two groups at random, group I is that pig house uses disinfection apparatus and control group after using herbal sprinkling of the present invention, group II be the pig house method that uses disinfection apparatus and disinfection tool also to use to lime as a control group.
Each group of pig free choice feeding, drinking-water, Routine Management; Raise identical number of days, pig symptom is observed during 9:00 and 16:00 every day, dead pig is weighed, anatomic observation pathological change, and perform detailed record, carry out weighing to not dead pig, dissecting for ten days to test, and recorded pathology situation, after having tested, data statistics is carried out to sick/dead rate of test, sick pig rate=sick pig number ÷ pig sum.Concrete outcome is in table 5.
Table 5
All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (3)
1. the medicine of a hog house disinfection, it is characterized in that: be by azedarach, camphortree leaf, myrrh, climbing groundsel, Lygodium japonicum, goldenrod, frankincense, honeysuckle, peppermint, orange peel, moutan bark, Chinese tuliptree bark, dandelion, denseflower indigo leaf, Lappula echinata and grassleaf sweetflag leaf, amount to 16 taste Chinese medicinal herbs compositions.
2. the medicine of a kind of hog house disinfection according to claim 1, it is characterized in that: the ratio of weight and number of each component in described medicine is, described azedarach 50 ~ 60 weight portion, described camphortree leaf 30 ~ 35 weight portion, described myrrh 15 ~ 20 weight portion, described climbing groundsel 15 ~ 20 weight portion, described Lygodium japonicum 15 ~ 20 weight portion, described goldenrod 10 ~ 15 weight portion, described frankincense 20 ~ 25 weight portion, described honeysuckle 10 ~ 15 weight portion, described peppermint 10 ~ 15 weight portion, described orange peel 20 ~ 25 weight portion, described moutan bark 10 ~ 15 weight portion, described Chinese tuliptree bark 20 ~ 25 weight portion, described dandelion 20 ~ 25 weight portion, described denseflower indigo leaf 20 ~ 25 weight portion, described Lappula echinata 10 ~ 15 weight portion and described grassleaf sweetflag leaf 15 ~ 20 weight portion.
3. the medicine of a kind of hog house disinfection according to claim 1 and 2 any one, is further characterized in that: medicine of the present invention is prepared from by the following method:
The first step, loads azedarach, myrrh, Lappula echinata, orange peel, moutan bark, Chinese tuliptree bark in multi-function extractor, adds alcohol heating reflux and extracts, merge extract, centrifugal, filter, obtain filtered fluid, reduced pressure concentration reclaims ethanol, obtain medicinal extract, by medicinal extract stored refrigerated, enter in spray dryer dry subsequently, pulverize with cracker and sieve, obtaining granularity is 50 ~ 100 object powder;
Second step, will remain herbal raw material difference boiling 2 ~ 4 times, merge respective decoction liquor, filter, left undisturbed overnight, extract supernatant, reduced pressure concentration, except anhydrating, is dried to dry cream respectively, pulverizes and sieves, and obtains 70 ~ 120 order powder;
3rd step, drops into above-mentioned powder in agitator during use and is stirred to evenly under normal temperature and pressure conditions, be added in warm water and obtain described disinfection of Chinese drug medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310660511.1A CN103689010B (en) | 2013-12-09 | 2013-12-09 | Medicine for hog house disinfection |
Applications Claiming Priority (1)
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| CN104488532A (en) * | 2014-12-30 | 2015-04-08 | 广西乐业县顾式茶有限公司 | Method for space auxiliary sterilization of livestock houses by natural fragrance of grasses and flowers |
| CN105148309A (en) * | 2015-08-25 | 2015-12-16 | 郎溪县凌达养猪专业合作社 | Swine excrement deodorant containing Chinese herbal medicinal ingredients |
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| CN105211131A (en) * | 2015-08-25 | 2016-01-06 | 郎溪县凌达养猪专业合作社 | Pigsty sterilizing preparation |
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| CN106035428A (en) * | 2016-05-26 | 2016-10-26 | 安徽禹王养殖有限公司 | Chinese herbal medicine sanitizer used in pig farm and preparing method thereof |
| CN106305610A (en) * | 2016-08-23 | 2017-01-11 | 合肥申仁养殖有限公司 | Culture method of breast-feed sows |
| CN106342963A (en) * | 2016-08-28 | 2017-01-25 | 广西兴胜农牧有限公司 | Hog house disinfectant |
| CN106344942A (en) * | 2016-08-28 | 2017-01-25 | 广西兴胜农牧有限公司 | Hog house disinfecting method |
| CN106342951A (en) * | 2016-08-28 | 2017-01-25 | 广西兴胜农牧有限公司 | Disinfectant special for pigpen |
| CN106359282A (en) * | 2016-08-31 | 2017-02-01 | 李宏强 | Baby rex rabbit confined farming method |
| CN106857709A (en) * | 2017-03-14 | 2017-06-20 | 滁州新源农业科技有限公司 | One kind raises region pond bactericide and preparation method scattered for black pig |
| CN107396886A (en) * | 2017-08-25 | 2017-11-28 | 贵港正邦农牧科技有限公司 | A kind of fast well-fattened pig-breeding method |
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| CN109042348A (en) * | 2018-08-09 | 2018-12-21 | 广西辽大农业科技集团股份有限公司 | A kind of piggery system |
| CN114631481A (en) * | 2020-12-15 | 2022-06-17 | 广东诸阁靓动物药业有限公司 | Prevent virus infection's novel pig house |
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