CN107468550B

CN107468550B - Application of aged coal degradation liquid in cosmetics

Info

Publication number: CN107468550B
Application number: CN201710535186.4A
Authority: CN
Inventors: 秦谊; 李宝才; 张敉; 张惠芬; 戴伟锋; 角仕云
Original assignee: Kunming University of Science and Technology
Current assignee: Kunming University of Science and Technology
Priority date: 2017-07-04
Filing date: 2017-07-04
Publication date: 2021-03-02
Anticipated expiration: 2037-07-04
Also published as: CN107468550A

Abstract

The invention relates to application of the degraded liquid of the young coal in cosmetics, when the degraded liquid of the young coal is used as a main material or a matrix of the cosmetics, the degraded liquid of the young coal can generate or enhance the effects of shrinking pores, balancing grease secretion, regulating the pH value of skin, preserving moisture, removing cutin and the like of the cosmetics, and liquid cosmetics such as toner, smoothing toner, makeup remover, firming toner, beauty fluid, liquid mask and the like prepared by taking the degraded liquid of the young coal as the main material or the matrix have obvious functions and strong pertinence; no or little chemicals are added, so that the product is safe and has no side effect; the raw materials are easy to obtain, the cost is low, the preparation and industrialization are easy, and the application prospect is wide.

Description

Application of aged coal degradation liquid in cosmetics

Technical Field

The invention relates to application of a degradation liquid of young coal in cosmetics, belonging to the field of daily chemicals.

Background

At present, various cosmetics on the market are prepared by blending and processing chemical raw materials, and particularly contain various pigments, spices, preservatives, bactericides and special functional compounds (such as components for hair growing, hair dyeing, breast beautifying, body building, deodorization, freckle removal, sun protection and the like). Excessive chemical intervention may cause immediate or potential harm to the human body, such as allergic reactions, skin aging, cosmetic dermatitis, induction of carcinogenesis, and the like. Some cosmetics improve their own functions and safety by adding a small amount of natural active ingredients, but most of them are mainly chemicals. The cosmetics which are not added with or added with few chemicals and take natural substances from animals and plants as main raw materials or matrixes have more advantages in the aspects of use effect and safety, and are also research and development hotspots in the field of current international cosmetics.

The inventor's research group found a colorless and transparent distillate, which has a pH value of 2 to 3, when the oxidizing agent is used to perform oxidative degradation on the annual green coal such as brown coal, peat and the like, and is called the annual green coal degradation liquid. Researches find that the degradation liquid of the young coal contains a large amount of various small-molecular organic acids, a small amount of small-molecular alcohols and esters, and the whole solution is weakly acidic, tastes sour and heavy, is mild and non-irritating, and has strong astringency; and also a special featureThat is, although the small molecules are contained in a large number of types, the relative content of each small molecule is extremely low, the total organic matter content is also extremely low, and the solution density is 1.01 to 1.05g/cm³The same as pure water; meanwhile, no toxic substance was detected by chemical composition analysis (J. chem. pharm. Res., 2014, 6: 2456-2459). The annual green coal degradation liquid has the characteristics of weak acidity, strong astringency, no color, transparency, primary distillate, no heavy metal, no microorganism and the like, and is suitable for being applied to liquid cosmetics with certain functions.

Disclosure of Invention

The invention takes the degradation liquid of the youth coal as the main raw material or the substrate to prepare various liquid cosmetics, and applies the novel natural product to the field of cosmetics for the first time.

The invention provides application of a degraded solution of young coal in cosmetics, and fills the gap of application of a novel natural product in the field of daily chemicals by developing a series of liquid cosmetics taking the degraded solution of young coal as a main raw material or a matrix.

The application of the degradation liquid of the youth coal in cosmetics is the application of the degradation liquid of the youth coal as a main material or a matrix of the cosmetics, and chemicals are not added or are less added.

The aged coal degradation liquid is added into liquid cosmetics such as toner, smoothing toner, makeup remover, firming toner, beauty fluid and liquid mask, and by controlling reasonable addition amount and proper process conditions, the structure of the product is not damaged, adverse effect on the stability of the cosmetics is not brought, and quality problems such as color change, layering and the like are not caused.

The said degradation liquid of the young coal refers in particular to the degradation liquid of the young coal as described in the granted invention patent "a production method of degradation liquid of the young coal and its use" (application number CN 201410006333.5), the meaning and preparation method of which can refer to the content of the patent.

The aged coal degradation liquid contains a large amount of various small molecular organic acids, is weak in acidity as a whole, has strong astringency, and can produce or enhance the effects of shrinking pores, balancing grease secretion, regulating skin pH value, moisturizing, removing cutin and the like of cosmetics when being used as main materials or matrixes of the cosmetics.

In the specific preparation, the youth coal degradation liquid can be added into related cosmetics as a simple aqueous phase matrix or material according to a conventional production method or a traditional process of the liquid cosmetics, and the preparation method has no difficulty or special points for a person skilled in the art.

The invention has the beneficial effects that:

(1) the cosmetic has simple formula, takes natural active substances as main raw materials or matrix, takes chemical raw materials as auxiliary materials, and does not add or adds few chemicals.

(2) The used natural product is colorless and transparent primary distillate, and has the characteristics of no toxicity, sterility, no heavy metal, extremely low substance content and high activity, and good use safety.

(3) Liquid cosmetics such as toner, smoothing toner, makeup remover, firming toner, beauty fluid, liquid mask and the like prepared by taking the annual green coal degradation liquid as a main material or a matrix have obvious functions and strong pertinence; is safe and has no side effect; the raw materials are easy to obtain, the cost is low, the preparation and industrialization are easy, and the application prospect is wide.

Detailed Description

The present invention is further illustrated by the following examples, but the scope of the invention is not limited to the above-described examples.

Example 1

The young coal degradation liquid firming lotion for astringing pores and balancing oil secretion has the following formula:

100mL of aged coal degradation liquid;

30mL of ethanol;

4g of D-sorbitol;

0.04mL of jasmine essential oil;

66mL of distilled water.

The aged coal degradation liquid toner is obtained after uniformly mixing according to a conventional method, and the phenomena of layering, color change, smoking and the like are not generated after mixing, and the aged coal degradation liquid toner is not layered, discolored, smelled and precipitated after being stored for four weeks at normal temperature.

And (3) evaluating the efficacy: the effect of firming water and balancing grease secretion of the aged coal degradation liquid is evaluated by adopting a world-recognized SEBUMETER method, and the effect of astringing pores is evaluated by photographing and observing. The specific method comprises the following steps: selecting 30 subjects with oily skin and large pores, wherein the subjects are 18-60 years old and half male and female, and no oil control product is used 7 days before the test; during the test, a subject is required to clean the face, after 8 hours, the oil content of the skin in 6 areas, namely the left and right cheekbones of the face, the left and right cheeks at the intersection of the nose tip and the pupil, and the left and right sides at the intersection of the temple and the mouth corner, is respectively measured by a multifunctional skin tester (MPA multifunctional skin test platform of CK company, Germany), the average value is used as data for trying the oil of the front face of the product of the embodiment, and meanwhile, the detail of local pores is observed and photographed; the test subject smears a sample of the whole face 1 time in the morning and at night respectively, slightly rubs and beats the face for about three minutes, and after continuously trying for 7 days, the oil content of the face is measured by the same method; observing and comparing the change condition of facial pores, and obviously reducing the pores into obvious effect; convergence is effective, and coarseness is still ineffective; the facial oil data before and after trial is subjected to significance analysis, the content of the facial oil is reduced compared with that before trial,Pless than 0.01 is significant effect,Pless than 0.05 is effective (whereinP< 0.05 means 0.01 <P< 0.05, same below), others are invalid; the ratio of the above cases in all the subjects is calculated respectively, and the sum of the effective rate and the effective rate is the total effective rate. The aged coal degradation liquid in the formula is replaced by distilled water with the same volume, other components and proportion are unchanged, a comparison group of firming toner is prepared, 30 test subjects are selected for comparison test, and the test results are shown in the following table 1:

TABLE 1

The results show that the total effective rate of the aged coal degradation liquid group is far higher than that of the control group no matter the effect of astringing pores or balancing grease secretion, and no adverse reaction of skin occurs. The aged coal degradation liquid firming lotion can effectively achieve the effects of astringing pores and balancing grease secretion, and the moisture retention agent D-sorbitol in the formula can also play a role in moisture retention.

Example 2

The formula of the youth coal degradation liquid toner for regulating the pH value of skin comprises the following components:

150mL of aged coal degradation liquid;

0.01g of sodium bicarbonate;

20mL of ethanol;

0.04mL of rose essential oil;

30mL of distilled water.

The youth coal degradation liquid toner is obtained after being uniformly mixed according to a conventional method, and the phenomena of layering, color change, smoking and the like are not generated after the toner is mixed, and the toner is not layered, discolored, smelled and precipitated after being stored for four weeks at normal temperature.

The toner can be used for cleaning face in cosmetic, and has neutral or weakly alkaline pH value due to use of cleaning products such as face cleaning milk, or other reasons. The toner has the effects of balancing the pH value of the skin, adjusting the moisture of the skin and rapidly restoring the skin to a normal physiological state, so that the damage of the external environment and bacteria to the skin is reduced, the sodium bicarbonate can balance the pH value of the aged coal degradation liquid, the toner has buffering property, the effect of adjusting the pH value of the skin is better achieved, and the toner has the function of astringing pores.

And (3) evaluating the efficacy: selecting 30 female subjects with oily skin or dry skin, wherein the age is 18-60 years; before the test, a subject cleans the face with the face cleaning product, smears a sample on the whole face, slightly rubs and beats the face for about three minutes, measures the pH value of the skin in the forehead area with a multifunctional skin tester after 8 hours, and continuously tests for 14 days 1 time every day; the number of times the pH was in the range of 5.0-6.0 was recorded, which is the normal pH range for skin, 12-14 times was significant, 9-11 times was significant, and others were not. The ratio of the three cases in all the subjects is calculated respectively, and the sum of the effective rate and the effective rate is the total effective rate. The aged coal degradation liquid in the formula is replaced by distilled water, other components and the proportion are unchanged, the skin toner is prepared, 30 test subjects are selected for comparison test, and the test results are shown in the following table 2:

TABLE 2

The results show that the aged coal degradation liquid group has higher total effective rate, no adverse skin reaction and basically no effect of the control group. The skin-care toner can effectively achieve the effect of regulating the pH value of the skin, and has the effects of astringing pores and balancing the secretion of grease.

Example 3

A moisturizing liquid mask of aged green coal degradation liquid comprises the following formula:

187mL of aged coal degradation liquid;

6mL of propylene glycol;

3g of trehalose;

1g of hyaluronic acid;

9402 g of carbomer;

1g of arginine;

menthol 0.2 g.

The liquid mask of the aged green coal degradation liquid is obtained after uniformly mixing according to a conventional method, and the phenomena of layering, color change, smoking and the like are not generated after mixing, and the liquid mask of the aged green coal degradation liquid is stored for four weeks at normal temperature without the occurrence of layering, color change, smell and precipitation. In the formula, the aged green coal degradation liquid is matched with micromolecular moisturizing components (propylene glycol and trehalose) to form a moisturizing system of the liquid mask together with macromolecular moisturizing components (hyaluronic acid), and carbomer and arginine form a thickening system of the liquid mask.

And (3) efficacy test: selecting 30 subjects with dry skin, wherein the age is 18-60 years, and the subjects are half of the age of the male and the female; the test method comprises the steps of (1) cleaning the face of a test subject before testing, respectively measuring the moisture content of the skin of 6 areas, namely the left and right cheekbones of the face, the left and right cheeks at the intersection of the nose tip and the pupil, and the left and right sides at the intersection of the temple and the mouth corner by using a multifunctional skin tester after 1 hour, and taking the average value as the data of the moisture of the skin in the front of a trial product; the subject smears the sample on the whole face, and gently kneads and beats the face for about three minutesAfter 8h, the moisture content of the face is measured by the same method; the facial moisture data before and after trial are subjected to significance analysis, compared with the data before trial, the facial moisture is increased,Pless than 0.01 is significant effect,Pless than 0.05 is effective, others are ineffective; the test was performed 1 time per day for 7 days. The ratio of the above three conditions of all the subjects in 7 days is calculated, and the sum of the significant efficiency and the effective rate is the total effective rate. The aged coal degradation liquid in the formula is replaced by distilled water, other components and the proportion are unchanged, a liquid mask is prepared, 30 test subjects are selected for comparison test, and the test results are shown in the following table 3:

TABLE 3

The results show that the total effective rate of a moisturizing system can be obviously improved by taking the annual green coal degradation liquid as a matrix, and the adverse skin reaction rate can be reduced.

Example 4

The cleansing water for the aged coal degradation liquid comprises the following components in percentage by weight:

167mL of annual green coal degradation liquid;

4g of dipropylene glycol;

2g of polyoxyethylene polypropylene glycol;

tween-805 mL;

20mL of ethanol;

mint essential oil 0.06 mL.

The cleansing water is obtained by uniformly mixing according to a conventional method, and the phenomena of layering, color change, smoking and the like are not generated after mixing, and the cleansing water is stored at normal temperature for four weeks without layering, color change, smell and precipitation. The cleansing water with the formula is mainly used for cleansing and cleaning skin, the aged coal degradation liquid has the effects of shrinking pores and controlling grease secretion, and by taking the aged coal degradation liquid as a matrix and matching with polyhydric alcohols containing oleophylic-hydrophilic amphiprotic nature and a surfactant, a more excellent cleaning function can be obtained, and meanwhile, the cleansing water has the effects of regulating the pH value of the skin, moisturizing and the like.

Trial test: selecting 30 female subjects with healthy facial skin, wherein the age is 18-60 years; the test subjects were made up uniformly and lightly during the test, and the sample prepared in this example was used for makeup removal; the subjects record the cleaning effect and the skin feel after washing of the product and score the cleaning effect and the skin feel according to the degree of feeling, the better the effect, the higher the score, and the specific scoring criteria are shown in Table 4 below; the sum of the scores of all the items is a comprehensive score, the comprehensive score is effective between 24 and 30, the comprehensive score is effective between 18 and 23, and the other comprehensive score is ineffective; 1 consecutive trial daily for 7 days. The ratio of the above three conditions of all the subjects in 7 days is calculated, and the sum of the significant efficiency and the effective rate is the total effective rate.

TABLE 4

The aged coal degradation liquid in the formula is replaced by distilled water, other components and the proportion are unchanged, the aged coal degradation liquid is prepared into a makeup remover, 30 test subjects are selected for comparison test, and the test results are shown in the following table 5:

TABLE 5

The result shows that the total effective rate of cleansing the skin by the cleansing water can be improved by taking the youth coal degradation liquid as a matrix, particularly the obvious effect rate can be obviously improved, and the adverse reaction rate of the skin can be reduced. The cleansing water for the aged coal degradation liquid can effectively achieve the effects of cleansing and skin cleaning, and has the effects of regulating the pH value of the skin and moisturizing.

Example 5

The formula of the young coal degradation liquid smoothing toner for removing cutin comprises the following components:

167mL of annual green coal degradation liquid;

5g of glycolic acid;

3g of malic acid;

10mL of 1, 3-butanediol;

8mL of propylene glycol;

4006 g of polyethylene glycol;

tea tree essential oil is 1 mL.

The aged coal degradation liquid smoothing toner is obtained after uniformly mixing according to a conventional method, and the phenomena of layering, color change, smoking and the like are not generated after mixing, and the phenomena of layering, color change, smell and precipitation are not generated after storage for four weeks at normal temperature. According to the formula, the aged green coal degradation liquid is matched with tartaric acid such as glycolic acid and malic acid to help the skin remove aged cutin accumulated on the outer layer, promote the activation and renewal of epidermal cells, and help to repair poor skin symptoms such as large pores, acne and comedo, and the aged green coal degradation liquid is matched with small-molecule moisturizing components such as 1, 3-butanediol and propylene glycol to form a moisturizing system of the smoothing toner.

Trial test: and evaluating the effect of the youth coal degradation liquid on removing cutin by smoothing skin water by adopting a mode of combining functional detection and sensory evaluation. The specific method comprises the following steps: selecting 30 volunteers as test subjects, wherein the age is 18-60 years, the male and female are half, and no cutin removing skin care product is used 7 days before the test; when the test is started, a test subject is required to clean the face, the moisture content of the skin in 6 areas, namely the left and right cheekbones of the face, the left and right cheeks at the intersection line of the nose tip and the pupil and the left and right sides at the intersection line of the temple and the mouth corner, is respectively measured by a multifunctional skin tester after 1h, and the average value is used as the data of the moisture of the skin in the front of the trial product; smearing a sample of the whole face by a test subject, slightly kneading and beating the face for about three minutes, and respectively taking the sample in the morning and the evening every day; measuring the facial moisture content by the same method after 30 days, and scoring according to the percentage increase of the facial moisture content, wherein the increase is 1 score of 0 or less, 2 score of 0-5.99%, 3 score of 6.00-10.99%, 4 score of 11.00-20.00% and 5 score of more than 20.00%; meanwhile, three sensory indexes of removing cutin, softening cutin and smoothing skin are set, and the test subjects score the trial effects respectively, wherein the scoring interval is 1-5, and the better the effect is, the higher the score is; the sum of the score of the moisture index and the scores of the three sensory indexes is a comprehensive score, the comprehensive score is effective within 16-20, effective within 12-15 and ineffective in others; the ratio of the above cases in all the subjects is calculated respectively, and the sum of the effective rate and the effective rate is the total effective rate. The aged coal degradation liquid in the formula is replaced by distilled water, other components and proportion are unchanged, the aged coal degradation liquid is prepared into smoothing toner, 30 test subjects are selected for carrying out a control test, and the test results are shown in the following table 6:

TABLE 6

The results show that the total effective rate of softening skin water to remove cutin can be obviously improved by taking the youth coal degradation liquid as a matrix, particularly the effective rate can be obviously improved, and the adverse reaction rate of skin can be reduced. The aged coal degradation liquid smoothing toner can effectively achieve the effect of removing cutin, and has the effects of astringing pores, adjusting the pH value of skin, moisturizing and the like.

Example 6

The youth coal degradation liquid whitening emulsion comprises the following formula:

176mL of aged coal degradation liquid;

5g of arbutin;

3g of magnesium ascorbyl phosphate;

kojic acid dipalmitate 4 g;

6g of oleyl alcohol polyoxyethylene ether;

4g of glycerin monostearate;

2mL of pomegranate essential oil.

The whitening emulsion of the aged green coal degradation liquid is prepared by a conventional method, and the phenomena of layering, color change, smoking and the like are not found after mixing, and the whitening emulsion is not layered, discolored, smelled and precipitated after being stored for four weeks at normal temperature. The formula takes the youth coal degradation liquid as a matrix, is matched with a plurality of compounds with different whitening ways, has the functions of astringing pores, balancing grease secretion, adjusting the pH value of skin and the like while generating obvious whitening effect, has the functions of softening and loosening cutin, can enable active ingredients to permeate into the skin more easily by taking the youth coal degradation liquid as the matrix, promotes the activation and the renewal of epidermal cells, and enhances the whitening effect.

Evaluation of efficacy: selecting 30 female subjects with healthy facial skin, wherein the female subjects are 18-60 years old and do not use any whitening product within 30 days before the test begins; during the test, the test subject is required to clean the face, after 1 hour, the melanin contents of the skin in 6 areas, namely the left and right cheekbones of the face, the left and right cheeks at the intersection of the nose tip and the pupil, and the left and right sides at the intersection of the temple and the mouth corner, are respectively measured by a multifunctional skin tester, and the average value is used as the data of the melanin content of the skin before the product of the embodiment is tested; applying the whole face sample by the subject 1 time each day in the morning and evening, continuously trying for 60 days, and measuring the melanin content of the facial skin by the same method; the facial skin melanin content data before and after the trial is subjected to significance analysis, compared with the data before the trial, the facial skin melanin content is reduced,Pless than 0.01 is significant effect,Pless than 0.05 is effective, others are ineffective; the ratio of the above three cases in all the subjects is calculated respectively, and the sum of the significant efficiency and the effective rate is the total effective rate. The youth coal degradation liquid in the formula is replaced by distilled water, other components and the proportion are unchanged, the youth coal degradation liquid is prepared into a whitening emulsion, 30 test subjects are selected for carrying out a control test, and the test results are shown in the following table 7:

TABLE 7

The result shows that the total effective rate of whitening of the emulsion can be obviously improved by taking the youth coal degradation liquid as a matrix, and the adverse reaction rate of skin can be reduced.

Claims

1. The application of the degradation liquid of the annual green coal in the preparation of cosmetics is the degradation liquid of the annual green coal described in the patent with the application number of 201410006333.5.