CN107412678A - A kind of new medicine composition for treating diabetes and preparation method thereof - Google Patents

A kind of new medicine composition for treating diabetes and preparation method thereof Download PDF

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Publication number
CN107412678A
CN107412678A CN201710663275.7A CN201710663275A CN107412678A CN 107412678 A CN107412678 A CN 107412678A CN 201710663275 A CN201710663275 A CN 201710663275A CN 107412678 A CN107412678 A CN 107412678A
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medicine composition
root
diabetes
chinese medicine
new medicine
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罗娟
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Chengdu Feilong Water Treatment Technology Institute
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Chengdu Feilong Water Treatment Technology Institute
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/41Crassulaceae (Stonecrop family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives

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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of new medicine composition for treating diabetes provided according to the understanding mechanism of TCM treatment of diabetes, each component and its mass parts ratio of the Chinese medicine composition are as follows:90~160g of the root of kudzu vine, 50~120g of pilose antler, 30~70g of silkworm chrysalis, 30~100g of semen allii tuberosi, 150~350g of saururus chinensis, 30~100g of root tuber of aromatic turmeric, 80~160g of paris polyphylla, 2~4g of the coptis, 90~160g of giant knotweed, 150~360g of stringy stonecrop;Medicine provided by the invention is a good Chinese prescription.

Description

A kind of new medicine composition for treating diabetes and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of new medicine composition for treating diabetes, particularly The field of the new medicine composition used for diabetic and preparation method thereof.
Background technology
Motherland's medical science thinks:Diabetes are one group of metabolic diseases characterized by hyperglycaemia.Hyperglycaemia is due to then pancreas Island element hyposecretion or its biological agent are damaged, or both have concurrently and cause.Long-standing hyperglycaemia during diabetes, causes various Tissue, particularly eye, kidney, heart, blood vessel, the chronic lesion of nerve and dysfunction.
Clinical manifestation:
A. drink, diuresis more than, eat and become thin more
Occur typical " three-many-one-little " symptom during severe hyperglycemia, be more common in type 1 diabetes.Generation ketosis or DKA When " three-many-one-little " symptom become apparent.
B. fatigue and weak, it is fat
It is more common in diabetes B.Diabetes B premorbid often has obesity, if cannot diagnose in time, body weight can be gradually reduced.
So, a kind of Chinese medicine composition for imitating treatment diabetes how is just found, is that those skilled in the art urgently will Solve the problems, such as.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment diabetes, people gradually appreciate Chinese traditional treatment The advantages of diabetes, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment sugar The present situation of disease is urinated, the purpose of the present invention is to be to provide a kind of new medicine composition for treating diabetes, to solve diabetes The problem of patient gets well early.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts Than can effectively treat above-mentioned diabetes.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:There is provided and a kind of treat the new of diabetes Type Chinese medicine composition and preparation method thereof, it is characterised in that each component and its mass parts ratio of the Chinese medicine composition are as follows It is shown:
90~160g of the root of kudzu vine, 50~120g of pilose antler, 30~70g of silkworm chrysalis, 30~100g of semen allii tuberosi, 150~350g of saururus chinensis, root tuber of aromatic turmeric 30~100g, 80~160g of paris polyphylla, 2~4g of the coptis, 90~160g of giant knotweed, 150~360g of stringy stonecrop.
A kind of new medicine composition for treating diabetes and preparation method thereof, it is characterised in that the Chinese medicine composition Each component and its mass parts than as follows:
100~130g of the root of kudzu vine, 60~105g of pilose antler, 38~60g of silkworm chrysalis, 38~90g of semen allii tuberosi, 180~310g of saururus chinensis, root tuber of aromatic turmeric 38~90g, 90~130g of paris polyphylla, 2.5~3.5g of the coptis, 100~140g of giant knotweed, 180~320g of stringy stonecrop.
A kind of new medicine composition for treating diabetes and preparation method thereof, it is characterised in that " preferred plan " Chinese medicine composition each component and its mass parts than as follows:
Root of kudzu vine 115g, pilose antler 95g, silkworm chrysalis 52g, semen allii tuberosi 80g, saururus chinensis 280g, root tuber of aromatic turmeric 80g, paris polyphylla 115g, the coptis 3g, giant knotweed 120g, stringy stonecrop 280g.
A kind of new medicine composition for treating diabetes and preparation method thereof, it is characterised in that methods described is included such as Lower step is prepared:
A, after above-mentioned raw materials Chinese medicine being picked impurity, dust and dried, it is stand-by to be ground into superfine end according to mass parts ratio;
B, the method for preparing Chinese medicine capsules according to traditional common process and auxiliary material, ground superfine myrrh thing is sieved Afterwards, it is put into medicine device and is well mixed in the lump with auxiliary material, is then prepared into capsule(Total length is 23.3mm after its capsule is sealed, Medicinal powder capacity 0.4~0.5g/ grains), then sterilize, dispense, sealing.
A kind of new medicine composition for treating diabetes and preparation method thereof, it is characterised in that the instructions of taking is: By the capsule medicine prepared three times a day to take, once a dose in the morning, afternoon and evening, dosage 3g(6)/ time, warm water is sent Clothes.One month is a course for the treatment of.2~4 courses for the treatment of of medication, " three-many-one-little " and other all diseases disappear.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
The root of kudzu vine, nature and flavor:It is sweet, pungent, cool, have expelling pathogenic factors from muscles and skin bring down a fever, promote the production of body fluid, promoting eruption, Shengyang Zhixie the effect of, for treating fever caused by exogenous pathogens Headache, stiff nape and back, it is thirsty, quench one's thirst, measles without adequate eruption, hot dysentery, diarrhea, hypertension neck pain;
Pilose antler, nature and flavor:It is sweet, salty, warm, there is the effect of invigorating kidney yang, benefiting essence-blood, strengthening the bones and muscles, tune punching times, torr sore poison, for treating Under impotence involuntary emission, uterus cold infertile, thin thin, the tired, chilly of god, dizziness and tinnitus deafness, spinal column crymodynia, muscles and bones impotence, uterine bleeding band, cloudy subcutaneous ulcer The disease such as do not hold back;
Silkworm chrysalis, nature and flavor:It is sweet, salty, mild-natured, there is desinsection to treat infantile malnutrition due to digestive disturbances or intestinalparasites, the effect of promoting the production of body fluid to quench thirst, for treat tuberculosis, infantile malnutrition, Heating, roundworm disease, the disease such as quench one's thirst;
Semen allii tuberosi, nature and flavor:It is pungent, sweet, warm, there is the effect of warm filling liver kidney, establishing-Yang controlling nocturnal emission with astringent drugs, for treating impotence and seminal emission, waist and knee acid Bitterly, under enuresis frequent micturition, gonorrhoea band;
Saururus chinensis, nature and flavor:It is sweet, pungent, cold, there is the effect of clearing heat and detoxicating, inducing diuresis to remove edema, it is puckery for treating difficult urination, leaching drip Bitterly, leukorrhea, urinary tract infections, nephritic dropsy, the diseases such as sore swollen toxin, eczema are controlled outside;
Root tuber of aromatic turmeric, nature and flavor:It is pungent, bitter, cold, have regulating qi to disperse stagnation, heart fire-clearing upset-relieving, normalizing gallbladder to cure jaundice the effect of, for treat closed dysmenorrhea, Chest and abdomen swelling and pain, shouting pain, pyreticosis coma, epilepsy is gone mad, jaundice;
Paris polyphylla, nature and flavor:It is bitter, cold, it is slightly poisonous, there is the effect of clearing heat and detoxicating, swelling and pain relieving, for treating popular second Type encephalitis, stomachache, appendicitis, scrofula, tonsillitis, parotitis, mastitis, poisonous snake, insect-bite, sore swollen toxin;
The coptis, nature and flavor:It is bitter, cold, have clearing heat-fire, eliminating dampness, removing toxic substances the effect of, enter for treating pyreticosis heresy the heart channel of Hang-Shaoyin high fever, Irritated, delirium or the hematemesis of the absurd row of the urgent blood of excess heat, the damp and hot feeling of stuffiness in chest, diarrhea, dysentery, the vexed insomnia of heart-fire hyperactivity, gastropyretic vomiting Or rapid digestion of food and polyorexia, irascibility red eye, swell pain and pathopyretic ulcer, serious case of furuncle septicemia, swelling and aching of gum, aphthae, Ting ear, swelling of vulva, hemorrhoid The diseases such as blood, eczema, scald;
Giant knotweed, nature and flavor:Slight bitter, be slightly cold, have expelling wind and removing dampness, scattered stasis pain, it is relieving cough and reducing sputum the effect of, for treating joint numbness Bitterly, jaundice with damp-heat pathogen, Amenorrhea, abdominal mass, scald, injury from falling down, carbuncle sore tumefacting virus, coughing with a lot of sputum;
Stringy stonecrop, nature and flavor:It is sweet, light, cool, there is the effect of eliminating dampness and heat, removing toxic substances, for treating jaundice with damp-heat pathogen, difficult urination, carbuncle Swollen sore, acute hepatitis, chronic hepatitis.
Medicine of the present invention is the principle based on TCM treatment of diabetes, from the pathomechanism according to diabetes and pharmacological action Think:Diabetes one are demonstrate,proved, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, is had well to above-mentioned disease Therapeutic effect.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned diabetes, the medicine prepared using the formula Thing good drug efficacy, it is quick, it is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the tool of the present invention Body embodiment is described in further detail:
Embodiment 1:
A kind of new medicine composition for treating diabetes, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows:
Root of kudzu vine 115g, pilose antler 95g, silkworm chrysalis 52g, semen allii tuberosi 80g, saururus chinensis 280g, root tuber of aromatic turmeric 80g, paris polyphylla 115g, the coptis 3g, giant knotweed 120g, stringy stonecrop 280g.
Embodiment 2:
A kind of new medicine composition for treating diabetes, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows:
Root of kudzu vine 130g, pilose antler 105g, silkworm chrysalis 60g, semen allii tuberosi 90g, saururus chinensis 310g, root tuber of aromatic turmeric 90g, paris polyphylla 130g, Huang Even 3.5g, giant knotweed 140g, stringy stonecrop 320g.
Embodiment 3:
A kind of new medicine composition for treating diabetes, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows:
Root of kudzu vine 160g, pilose antler 120g, silkworm chrysalis 70g, semen allii tuberosi 100g, saururus chinensis 350g, root tuber of aromatic turmeric 100g, paris polyphylla 160g, Coptis 4g, giant knotweed 160g, stringy stonecrop 360g.
Model case
Through clinical conditions diabetic totally 1260, the age is 860 of more than 59 years old, only 400 for 59 years old with Under." three-many-one-little " and other symptoms disappear in 1260 patients 955, effective 135, invalid 170.It is total effective Rate is up to 86.5%.

Claims (3)

  1. A kind of 1. new medicine composition for treating diabetes, it is characterised in that each component of the Chinese medicine composition and its Mass parts are than as follows:
    90~160g of the root of kudzu vine, 50~120g of pilose antler, 30~70g of silkworm chrysalis, 30~100g of semen allii tuberosi, 150~350g of saururus chinensis, root tuber of aromatic turmeric 30~100g, 80~160g of paris polyphylla, 2~4g of the coptis, 90~160g of giant knotweed, 150~360g of stringy stonecrop.
  2. 2. the new medicine composition for the treatment of diabetes according to claim 1, it is characterised in that the Chinese medicine composition Each component and its mass parts than as follows:
    100~130g of the root of kudzu vine, 60~105g of pilose antler, 38~60g of silkworm chrysalis, 38~90g of semen allii tuberosi, 180~310g of saururus chinensis, root tuber of aromatic turmeric 38~90g, 90~130g of paris polyphylla, 2.5~3.5g of the coptis, 100~140g of giant knotweed, 180~320g of stringy stonecrop.
  3. 3. the new medicine composition of the treatment diabetes according to claim 1 to 2, it is characterised in that the Chinese medicine group The each component and its mass parts of compound are than as follows:
    Root of kudzu vine 115g, pilose antler 95g, silkworm chrysalis 52g, semen allii tuberosi 80g, saururus chinensis 280g, root tuber of aromatic turmeric 80g, paris polyphylla 115g, the coptis 3g, giant knotweed 120g, stringy stonecrop 280g.
CN201710663275.7A 2017-08-05 2017-08-05 A kind of new medicine composition for treating diabetes and preparation method thereof Withdrawn CN107412678A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111135247A (en) * 2020-01-22 2020-05-12 河南中医药大学 Traditional Chinese medicine for treating stage IV diabetic nephropathy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111135247A (en) * 2020-01-22 2020-05-12 河南中医药大学 Traditional Chinese medicine for treating stage IV diabetic nephropathy

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