CN107496860A - A kind of capsule medicine for treating diabetes and preparation method thereof - Google Patents

A kind of capsule medicine for treating diabetes and preparation method thereof Download PDF

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Publication number
CN107496860A
CN107496860A CN201710684834.2A CN201710684834A CN107496860A CN 107496860 A CN107496860 A CN 107496860A CN 201710684834 A CN201710684834 A CN 201710684834A CN 107496860 A CN107496860 A CN 107496860A
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medicine
chinese
diabetes
ginseng
capsule
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孙素蓉
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Chengdu Fengmi Biotechnology Co Ltd
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Chengdu Fengmi Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate

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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of capsule medicine for treating diabetes provided according to the understanding mechanism of TCM treatment of diabetes, each component and its mass parts ratio of the medicine are as follows:90~350g of the Radix Astragali, 150~300g of Chinese yam, 100~160g of sealwort, 30~160g of ginseng, 100~160g of chrysanthemum, 100~160g of radix polygonati officinalis, 50~150g of the fruit of Chinese wolfberry, 30~80g of American Ginseng, 60~160g of balsam pear, 150~300g of lotus rhizome, 30~100g of ginger, 100~160g of the root of kudzu vine, medicine provided by the invention are a good Chinese prescriptions.

Description

A kind of capsule medicine for treating diabetes and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for treating diabetes, particularly for sugar The field of the capsule medicine that urine patient uses and preparation method thereof.
Background technology
Doctor thinks:Diabetes are one group of metabolic diseases characterized by hyperglycaemia.Hyperglycaemia is due to then insulin Hyposecretion or its biological agent are damaged, or both have concurrently and cause.Long-standing hyperglycaemia during diabetes, causes various groups Knit, particularly eye, kidney, heart, blood vessel, the chronic lesion of nerve, dysfunction.
Clinical manifestation:
A. drink, diuresis more than, eat and become thin more
Occur typical " three-many-one-little " symptom during severe hyperglycemia, be more common in type 1 diabetes.Generation ketosis or DKA When " three-many-one-little " symptom become apparent.
B. fatigue and weak, it is fat
It is more common in diabetes B.Diabetes B premorbid often has obesity, if cannot diagnose in time, body weight can be gradually reduced.
So, a kind of Chinese medicine composition for imitating treatment diabetes how is just found, is that those skilled in the art urgently will Solve the problems, such as.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment diabetes, people gradually appreciate Chinese traditional treatment The advantages of diabetes, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment sugar The present situation of disease is urinated, the purpose of the present invention is to be to provide a kind of capsule medicine for treating diabetes, to solve diabetic The problem of getting well early.The medicine be using common Chinese medicine as raw material, can by selecting rational medicine and mass parts ratio Effectively treat above-mentioned diabetes.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:A kind of glue for treating diabetes is provided Wafer medicine and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows:
90~350g of the Radix Astragali, 150~300g of Chinese yam, 100~160g of sealwort, 30~160g of ginseng, 100~160g of chrysanthemum, radix polygonati officinalis 100~160g, 50~150g of the fruit of Chinese wolfberry, 30~80g of American Ginseng, 60~160g of balsam pear, 150~300g of lotus rhizome, ginger 30~ 100g, 100~160g of the root of kudzu vine.
A kind of capsule medicine for treating diabetes and preparation method thereof, it is characterised in that each component of the medicine And its mass parts are than as follows:
100~310g of the Radix Astragali, 180~260g of Chinese yam, 115~130g of sealwort, 38~130g of ginseng, 115~130g of chrysanthemum, radix polygonati officinalis 115~130g, 58~130g of the fruit of Chinese wolfberry, 38~70g of American Ginseng, 70~130g of balsam pear, 180~260g of lotus rhizome, ginger 38~ 90g, 115~130g of the root of kudzu vine.
A kind of capsule medicine for treating diabetes and preparation method thereof, it is characterised in that the medicine of " preferred plan " The each component and its mass parts of thing are than as follows:
Radix Astragali 280g, Chinese yam 230g, sealwort 118g, ginseng 115g, chrysanthemum 118g, radix polygonati officinalis 118g, fruit of Chinese wolfberry 115g, American Ginseng 60g, balsam pear 115g, lotus rhizome 230g, ginger 80g, root of kudzu vine 118g.
A kind of capsule medicine for treating diabetes and preparation method thereof, it is characterised in that methods described includes following step Suddenly it is prepared:
A. ginseng, American Ginseng and the Radix Astragali are removed(It is ground into fine powder)Outside, after above-mentioned other raw material Chinese medicines being picked into impurity and dust, press Decocted a drug wrapped according to mass parts than being ground into coarse altogether;
B. 1. the raw material Chinese medicine wrapped is put into cold boiling water and soaks 60min, then again by soaked medicine and soak medicine Clarified solution be put into the lump in marmite, injected medicine 65mm cold boiling water carry out first time high heat decoction, wait decoct arrive 15min When, turn slow fire and boil 45 min, leaching decoction;2. the tepor boiling water that medicine 60mm was re-injected in the dregs of a decoction carries out second of intense fire Decoct, when 10min is arrived in decoction, turn slow fire and boil 35 min, leaching decoction;3. decoction mixing twice is condensed into clear cream, it is cold To room temperature, adding ethanol makes alcohol content stir up to 70~80wt%, stand 22~26 hours, take supernatant, reclaim ethanol Afterwards again by supernatant concentration into clear cream.
C. the method for preparing Chinese medicine capsules according to tradition, after ground fine powder is crossed into 100 mesh sieves, produces superfine myrrh Powder is 1.;Clear cream is added in medicinal powder, it is filling into capsule after mixing, sterilizing, drying, crushing, produce capsule 2., 3. and then throw Light, sterilization, sealed packaging.
A kind of capsule medicine for treating diabetes and preparation method thereof, it is characterised in that the instructions of taking is:Will system The capsule medicine got ready is three times a day to take, and early, middle and late once a dose, dosage 3g(5)/ time, take within one hour after meal (Taboo:1. serious renal insufficiency, diabetes mellitus DKA, stupor, insulin-dependent diabetic and pregnant woman prohibit With;Monitoring blood glucose is please noted during medication, and dosage is adjusted according to blood glucose), while the conditioning that is careful in one's diet, three meals in a day will advise Rule, food-intake and dieting are controlled, to be eaten less such as frying and containing sugared high, 20 days are a course for the treatment of, 3~5 courses for the treatment of of taking medicine, blood glucose Substantially delayed or controlled, so as to reduce the generation of complication.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
The Radix Astragali, nature and flavor:Sweet, tepor, there is the effect of invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation, for treating the deficiency of vital energy Weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, burst for a long time and does not holds back, The diseases such as flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes, chronic rephrilis protinuria, diabetes;
Chinese yam, nature and flavor:It is sweet, flat, have tonifying spleen, support lung, reinforce the kidney, strengthening the essence the effect of, for treat splenasthenic diarrhea, deficiency of food edema, Deficiency syndrome of the lung cough and asthma, quench one's thirst, pass out semen, with, kidney deficiency frequent micturition, the diseases such as carbuncle swells, scrofula are controlled in external application;
Sealwort, nature and flavor:It is sweet, flat, have Yin nourishing and lung moistening, invigorate the spleen and benefit qi, Zishen fill fine the effect of, for treating deficiency of Yin overstrain cough, lung Cough caused by dryness is coughed, insufficiency of the spleen weak, few dry of food, quench one's thirst, deficiency of the kidney soreness and weakness of waist and knees, impotence and seminal emission, tinnitus mesh are dark, poliosis, physically weak win The diseases such as thin, wind favus disease;
Ginseng, nature and flavor:Sweet slight bitter, temperature, have reinforce vital energy, prevent prolapse and engender liquid, the effect of calming the nerves, for treating, internal lesion caused by overexertion is deficient, food Less, burnout, regurgitation and emesis, stool lingering diarrhea, cough of deficient and syndrome characterized by dyspnea, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition, disappear Yearningly, the disease such as woman uterine bleeding, infantile chronic fright and perennial and irrecoverable weakness, all qi-blood-body fluid deficiencies;
Chrysanthemum, nature and flavor:Sweet, bitter, cold nature, there is the effect of wind and heat dispersing, flat liver improving eyesight, removing toxicity for detumescence, it is outer for treating Wind or wind-warm syndrome are felt from the beginning of, the disease such as fever and headache, dizziness, red eye, swell pain, furuncle swelling toxin;
Radix polygonati officinalis, nature and flavor:It is sweet, flat, have yin-nourishing, moisturize, relieving restlessness, the effect of quenching the thirst, for treat pyreticosis impairment of yin, cough polydipsia, Deficient fever, the paddy that disappears are easily hungry, frequent urination;
The fruit of Chinese wolfberry, nature and flavor:It is sweet, mild-natured, have nourishing the liver, nourshing kidney, moistening lung the effect of, for treat caused by liver and kidney deficiency, have a dizzy spell, Visual one is clear, soreness and weakness of waist and knees, the expensive essence of impotence, cough due to consumptive disease, quenches one's thirst to draw and the disease such as drinks;
American Ginseng, nature and flavor:It is sweet, slight bitter, cold in nature, there is boosting qi and nourishing yin, the effect of promoting the production of body fluid of relieving inflammation or internal heat, for treating the cloudy specially fire of the deficiency of vital energy The diseases such as the tired tired, Heat Diabetes of prosperous, cough phlegm blood, abnormal heat, the dry cigarette of mouth be dry;
Balsam pear, nature and flavor:It is bitter, cold in nature, there is the effect of heat-relieving, improving eyesight, removing toxic substances, for treating hot summer weather polydipsia, quenching one's thirst, red Eye pain, dysentery, sore and toxic;
Lotus rhizome, nature and flavor:It is sweet, cold, have clearing heat and promoting fluid, cool blood, dissipate the stasis of blood, hemostasis the effect of, for treat pyreticosis polydipsia, hematemesis, The diseases such as lower blood;
Ginger, nature and flavor:Pungent, tepor, there is the effect of relieving exterior syndrome and dispelling cold, warming middle energizer to arrest vomiting, warm lung cough-relieving, preventing phlegm from forming and stopping coughing, removing toxic substances, be used for Treatment is caught cold and stomach cold the is vomitted disease such as inverse;
The root of kudzu vine, nature and flavor:It is sweet, pungent, flat, have expelling pathogenic factors from muscles and skin bring down a fever, deliver examine, promote the production of body fluid to quench thirst, Shengyang Zhixie the effect of, for treating Fever caused by exogenous pathogens, rigidity of nape and headache, measles go out that not smooth, warm disease is thirsty, diabete, diarrhea, dysentery, hypertension, coronary heart disease etc. from the beginning of, rash Disease.
Medicine of the present invention is the principle based on traditional Chinese medical science diabetes, is recognized from the pathomechanism according to diabetes and pharmacological action For:With regard to diabetes, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good effect to above-mentioned disease.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned diabetes, the medicine prepared using the formula Thing good drug efficacy, it is quick, it is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the tool of the present invention Body embodiment is described in further detail:
Embodiment 1:
A kind of capsule medicine for treating diabetes, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown:
Radix Astragali 280g, Chinese yam 230g, sealwort 118g, ginseng 115g, chrysanthemum 118g, radix polygonati officinalis 118g, fruit of Chinese wolfberry 115g, American Ginseng 60g, balsam pear 115g, lotus rhizome 230g, ginger 80g, root of kudzu vine 118g.
Embodiment 2:
A kind of capsule medicine for treating diabetes, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown:
Radix Astragali 310g, Chinese yam 260g, sealwort 130g, ginseng 130g, chrysanthemum 130g, radix polygonati officinalis 130g, fruit of Chinese wolfberry 130g, American Ginseng 70g, balsam pear 130g, lotus rhizome 260g, ginger 90g, root of kudzu vine 130g.
Embodiment 3:
A kind of capsule medicine for treating diabetes, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown:
Radix Astragali 350g, Chinese yam 300g, sealwort 160g, ginseng 160g, chrysanthemum 160g, radix polygonati officinalis 160g, fruit of Chinese wolfberry 150g, American Ginseng 80g, balsam pear 160g, lotus rhizome 300g, ginger 100g, root of kudzu vine 160g.
Allusion quotation case
Through clinical conditions diabetic totally 1500, the age is 900 of more than 50 years old, only 600 for 50 years old with Under.Blood glucose is substantially delayed or controlled in 1500 patients 1000, effective 365, invalid 135.It is total effective Rate is up to 90%.

Claims (3)

1. a kind of capsule medicine for treating diabetes, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower:
90~350g of the Radix Astragali, 150~300g of Chinese yam, 100~160g of sealwort, 30~160g of ginseng, 100~160g of chrysanthemum, radix polygonati officinalis 100~160g, 50~150g of the fruit of Chinese wolfberry, 30~80g of American Ginseng, 60~160g of balsam pear, 150~300g of lotus rhizome, ginger 30~ 100g, 100~160g of the root of kudzu vine.
2. the capsule medicine for the treatment of diabetes according to claim 1, it is characterised in that each component of the medicine And its mass parts are than as follows:
100~310g of the Radix Astragali, 180~260g of Chinese yam, 115~130g of sealwort, 38~130g of ginseng, 115~130g of chrysanthemum, radix polygonati officinalis 115~130g, 58~130g of the fruit of Chinese wolfberry, 38~70g of American Ginseng, 70~130g of balsam pear, 180~260g of lotus rhizome, ginger 38~ 90g, 115~130g of the root of kudzu vine.
3. the capsule medicine of the treatment diabetes according to claim 1 to 2, it is characterised in that the medicine it is each Component and its mass parts are than as follows:
Radix Astragali 280g, Chinese yam 230g, sealwort 118g, ginseng 115g, chrysanthemum 118g, radix polygonati officinalis 118g, fruit of Chinese wolfberry 115g, American Ginseng 60g, balsam pear 115g, lotus rhizome 230g, ginger 80g, root of kudzu vine 118g.
CN201710684834.2A 2017-08-11 2017-08-11 A kind of capsule medicine for treating diabetes and preparation method thereof Pending CN107496860A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111888431A (en) * 2020-08-17 2020-11-06 江西优培文化传媒有限公司 Composition for treating diabetes and preparation method thereof
CN112587635A (en) * 2020-12-24 2021-04-02 重庆百草太兴生物技术有限公司 Chinese herbal medicine for treating damaged pancreatic tissue, package and production method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104208420A (en) * 2014-09-05 2014-12-17 苏赵珍 Traditional Chinese medicine for treating diabetes mellitus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104208420A (en) * 2014-09-05 2014-12-17 苏赵珍 Traditional Chinese medicine for treating diabetes mellitus

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111888431A (en) * 2020-08-17 2020-11-06 江西优培文化传媒有限公司 Composition for treating diabetes and preparation method thereof
CN112587635A (en) * 2020-12-24 2021-04-02 重庆百草太兴生物技术有限公司 Chinese herbal medicine for treating damaged pancreatic tissue, package and production method thereof

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Application publication date: 20171222