CN106266487A - A kind of Chinese medicine composition treating diabetes and preparation method thereof - Google Patents

A kind of Chinese medicine composition treating diabetes and preparation method thereof Download PDF

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CN106266487A
CN106266487A CN201610897661.8A CN201610897661A CN106266487A CN 106266487 A CN106266487 A CN 106266487A CN 201610897661 A CN201610897661 A CN 201610897661A CN 106266487 A CN106266487 A CN 106266487A
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rhizoma
chinese medicine
medicine composition
diabetes
radix
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罗兴贵
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Chengdu Xing More Biotechnology LLC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/07Basidiomycota, e.g. Cryptococcus
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    • A61K36/236Ligusticum (licorice-root)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
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    • A61K36/80Scrophulariaceae (Figwort family)
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    • A61K36/80Scrophulariaceae (Figwort family)
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    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate

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Abstract

The invention belongs to field of traditional Chinese, purpose is a kind of Chinese medicine composition treating diabetes according to the traditional Chinese medical science, diabetes being recognized mechanism and providing, and each component of described Chinese medicine composition and mass parts ratio thereof are as follows: the Rhizoma Anemarrhenae 100~260g, Rhizoma Alismatis 100~200g, the Rhizoma Atractylodis Macrocephalae 80~160g, Rhizoma Atractylodis 80~160g, Fructus Gardeniae 100~220g, Radix Scrophulariae 150~260g, Rhizoma Coptidis 25~50g, Radix Salviae Miltiorrhizae 80~160g, Rhizoma Chuanxiong 50~120g, Pollen Typhae 50~120g, Herba Euphorbiae Humifusae 100~160g, Poria 150~260g, the Radix Rehmanniae 100~320g;The medicine that the present invention provides is the Chinese prescription of a treating both the principal and secondary aspects of a disease.

Description

A kind of Chinese medicine composition treating diabetes and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, be specifically related to a kind of Chinese medicine composition treating diabetes, particularly for sugar The field of the Chinese medicine composition that urine patient uses and preparation method thereof.
Background technology
Diabetes (diabetes) are that the glucose in a kind of blood easily piles up too much disease, domestic logical to its symptom Commonly referred to as " hyperglycemia ", being together referred to as " three high " with hypertension, hyperlipidemia is by inherited genetic factors, immunologic function disorder, microorganism The various virulence factors such as infection and toxin, free radical toxin, Nervous and Mental Factors act on body and cause hypoinsulinism, islets of langerhans A series of metabolism disorder syndromes such as sugar, protein, fat, water and the electrolyte that element opposing waits and causes.Abroad give the other of it Being named as " silent killer ", particularly " adult diabetes mellitus ", it is the highest that the middle age of more than 40 years old catches rate.
Diabetes can be divided into: the diabetes of type i diabetes, type Ⅱdiabetes mellitus, gestational diabetes and other specific types.
A, I type patients with type Ⅰ DM is a kind of autoimmune disease.Autoimmune disease is owing to the immune system of health is to certainly Body makes attack.The pancreas beta cell of self excreting insulin is made attack also by the immune system of diabetics Killing them, result pancreas can not secrete enough insulins.Because insulin secretion lacks, patient need to rely on exogenous islets of langerhans Element supplements to sustain life.
B, type Ⅱdiabetes mellitus are Adult Onset's patients with type Ⅰ DM, how 35~the sequela of 40 years old, account for diabetics 90% Above.The ability producing insulin in the patient not completely loses, and the insulin in the patient having even produces too much, but pancreas The action effect of island element is but had a greatly reduced quality, and insulin the most in the patient is a kind of shortage relatively.
C, gestational diabetes refer to the diabetes that women suffers from period of gestation.Clinical data shows about 2~3% Women can occur diabetes at period of gestation, and patient's diabetes after gestation disappear automatically.Gestational diabetes is easier to occur Fat and lying-in woman advanced in years.Type Ⅱdiabetes mellitus may be developed into after having the gestational diabetes women of nearly 30%.
So, just how to find a kind of Chinese medicine composition that can effectively treat diabetes, be that we are badly in need of solving at present Problem.
Summary of the invention
Along with the development of China's Chinese medicine, in treatment diabetes, people gradually appreciate Chinese traditional treatment The advantage of diabetes, and the advantage such as good effect, instant effect, toxic and side effects be little over the course for the treatment of, for existing western medical treatment sugar The present situation that urine is sick, it is an object of the invention to be to provide a kind of Chinese medicine composition treating diabetes, to solve diabetics The most restorative problem.This medicine is with common Chinese medicine as raw material, by selecting rational Chinese medicine composition and matter thereof Amount part ratio, can effectively treat above-mentioned diabetes.
For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provides a kind of and treats in diabetes Drug composition and preparation method thereof, it is characterised in that each component of described Chinese medicine composition and mass parts ratio thereof are as follows:
The Rhizoma Anemarrhenae 100~260g, Rhizoma Alismatis 100~200g, the Rhizoma Atractylodis Macrocephalae 80~160g, Rhizoma Atractylodis 80~160g, Fructus Gardeniae 100~220g, Radix Scrophulariae 150~260g, Rhizoma Coptidis 25~50g, Radix Salviae Miltiorrhizae 80~160g, Rhizoma Chuanxiong 50~120g, Pollen Typhae 50~120g, Herba Euphorbiae Humifusae 100~160g, Poria 150~260g, the Radix Rehmanniae 100~320g.
A kind of Chinese medicine composition treating diabetes and preparation method thereof, it is characterised in that described Chinese medicine composition each Individual component and mass parts ratio thereof are as follows:
The Rhizoma Anemarrhenae 115~230g, Rhizoma Alismatis 115~170g, the Rhizoma Atractylodis Macrocephalae 90~140g, Rhizoma Atractylodis 90~140g, Fructus Gardeniae 115~200g, Radix Scrophulariae 170~230g, Rhizoma Coptidis 28~45g, Radix Salviae Miltiorrhizae 90~140g, Rhizoma Chuanxiong 60~105g, Pollen Typhae 60~105g, Herba Euphorbiae Humifusae 115~140g, Poria 180~230g, the Radix Rehmanniae 115~280g.
A kind of Chinese medicine composition treating diabetes and preparation method thereof, it is characterised in that in described " preferred plan " Each component of drug composition and mass parts ratio thereof are as follows:
Rhizoma Anemarrhenae 200g, Rhizoma Alismatis 150g, Rhizoma Atractylodis Macrocephalae 120g, Rhizoma Atractylodis 120g, Fructus Gardeniae 170g, Radix Scrophulariae 200g, Rhizoma Coptidis 40g, Radix Salviae Miltiorrhizae 120g, river Rhizome of chuanxiong 90g, Pollen Typhae 90g, Herba Euphorbiae Humifusae 120g, Poria 200g, Radix Rehmanniae 250g.
A kind of Chinese medicine composition treating diabetes and preparation method thereof, it is characterised in that described method includes walking as follows Suddenly it is prepared from:
A, above-mentioned raw materials Chinese medicine is picked decontamination, dust and dried, be ground into superfine end according to mass parts ratio stand-by;
B, the method preparing Chinese medicine capsules according to tradition, after being sieved by ground superfine end Chinese medicine composition, put into medicine device Middle mix homogeneously, is then prepared as capsule (the sealed rear total length of its capsule is 23.3mm, medicated powder capacity 0.4~0.5g/ grain), And then sealed packaging.
A kind of Chinese medicine composition treating diabetes and preparation method thereof, it is characterised in that described instructions of taking is: will system The capsule medicine got ready is to take three times a day, and the morning, noon and afternoon service once, dosage 3.5g/ time, warm water delivery service.Within 8 weeks, it is One course for the treatment of, after three courses for the treatment of of taking medicine, blood glucose is normal, without big fluctuation, after gradually decrease dose, one course for the treatment of of following the service again, not Take hypoglycemic medicine again.
Each raw material Chinese medicine in prescription of the present invention all has detailed note in Chinese Pharmacopoeia, China's dictionary and China's book on Chinese herbal medicine Carry.The present invention selects most common of which Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:
The Rhizoma Anemarrhenae, nature and flavor: bitter in the mouth, cold in nature, there is clearing away heat-fire, nourshing Yin and drynsessmoistening prescription, effect of relieving restlessness of quenching the thirst, be used for treating epidemic febrile disease, High hot excessive thirst, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, stranguria with turbid discharge of quenching one's thirst;
Rhizoma Alismatis, nature and flavor: sweet, cold, there is diuretic, eliminating dampness by diuresis, effect of expelling the heat-evil, be used for treating dysuria, edema distension, vomiting, Dysentery, phlegm retention, tinea pedis, gonorrhea, hematuria;
The Rhizoma Atractylodis Macrocephalae, nature and flavor: bitter in the mouth, sweet, warm in nature, there is invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect, be used for treating temper The few abdominal distention of weakness, spiritlessness and weakness, lack of appetite, big loose stool are thin, fluid-retention stagnating in the interior, dysuria, edema, dizziness due to fluid-retention, temperature numbness are ached, gas Empty spontaneous perspiration, frequent fetal movement;
Rhizoma Atractylodis, nature and flavor: acrid in the mouth, hardship, warm in nature, there is drying damp and strengthening spleen, wind-damp dispelling, effect of improving eyesight, be used for treating the spleen and stomach being stranded by dampness, Asthenia drowsiness, born of the same parents' painful abdominal mass abdominal distention, inappetence, tell have loose bowels, phlegm retention, damp-edema, exterior syndrome wet, the head heavy sensation of the body pain of folder, arthromyodynia warm nature, podomere Ache weigh, the disease such as flaccidity folds in a garment, nyctalopia;
Fructus Gardeniae, nature and flavor: bitter, cold, there is effect of heat clearing away, pathogenic fire purging, removing heat from blood, be used for treating calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, Quench one's thirst, conjunctival congestion, pharyngalgia, haematemesis, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprain diseases such as swelling and ache;
Radix Scrophulariae, nature and flavor: bitter salty, cool, there is effect of YIN nourishing, pathogenic fire reducing, relieving restlessness, removing toxic substances, be used for treating consumption of YIN caused by febrile disease, tongue is unraveled silk tired Yearningly, send out speckle, hectic fever due to YIN-deficiency consumptive fever, night sleep peaceful, spontaneous sweating, constipation, hematemesis and epistaxis, laryngopharynx swelling and pain, carbuncle, scrofula, temperature poison are hindered in Tianjin Send out the diseases such as speckle, conjunctival congestion, diphtheria, sore;
Rhizoma Coptidis, nature and flavor: bitter, cold, there is effect of clearing away heat-fire, dampness, removing toxic substances, be used for treating calentura heresy enter height of heart channel hot, Irritated, delirium or the absurd row of intenseness of heat forcing blood tell nosebleed, the damp and hot feeling of stuffiness in chest, have loose bowels, the vexed insomnia of dysentery, hyperactivity of heart-fire, gastropyretic vomiting Or rapid digestion of food and polyorexia, liver-fire conjunctival congestion and swelling pain and pathopyretic ulcer, furunculosis septicemia, gingival swelling and pain, aphtha of the mouth and tongue, ear, swelling of the vulva, hemorrhoid The diseases such as blood, eczema, scald;
Radix Salviae Miltiorrhizae, nature and flavor: bitter in the mouth, cold nature, there is blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, nourishing blood to tranquillize the mind, effect of removing heat from blood eliminating carbuncle, be used for Treatment menoxenia, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, trusted subordinate's pain, lump in the abdomen, pyretic arthralgia swell and ache, traumatic injury, Heat enters nutrient blood, dysphoria, vexed insomnia, ulcerative carbuncle toxic swelling;
Rhizoma Chuanxiong, nature and flavor: pungent, warm, have that activating QI to alleviate the depression, method wind-dryness be wet, effect of promoting blood circulation and stopping pain, be used for treating air-cooled headache rotation Dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores, menoxenia, abdominal mass stomachache, breast are coerced and are stung Bitterly, tumbling and swelling, rheumatic arthralgia;
Pollen Typhae, nature and flavor: sweet in the mouth, micro-pungent, property are put down, and have effect of hemostasis, blood stasis dispelling, diuresis, be used for treating haematemesis, spitting of blood, epistaxis, Standby dysentery, have blood in stool, metrorrhagia, traumatic hemorrhage, trusted subordinate's pain, amenorrhea stomachache, stasis of blood pain in puerperal, dysmenorrhea, tumbling and swelling, blood strangury and dry pain, band Under, congenital deformity of the tongue, aphtha, ear, uncontrolled urination itch;
Herba Euphorbiae Humifusae, nature and flavor: acrid in the mouth, property are flat, have heat-clearing and toxic substances removing, dampness removing jaundice eliminating, effect of promoting blood circulation and hemostasis, be used for treating dysentery, Have loose bowels, jaundice, hemoptysis, haematemesis, hematuria, have blood in stool, metrorrhagia, agalactia, treating swelling and pain by traumatic injury and pathopyretic ulcer;
Poria, nature and flavor: sweet, light, flat, there is effect of eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming, be used for treating dysuria, Edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, have loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine;
The Radix Rehmanniae, nature and flavor: sweet in the mouth, hardship, cold in nature, there is effect of heat clearing away, removing heat from blood, be used for warming febrile disease and join the army blood, high fever coma, mouth Dry tongue is deep red.
Medicine of the present invention is principle based on TCM treatment of diabetes, thinks from pharmacological action and mechanism of action: with regard to glycosuria Disease, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, and above-mentioned disease is had good therapeutic effect.
Detailed description of the invention
The present invention is aiming at the treatment of above-mentioned diabetes and a kind of Chinese medicine formula of proposing, uses medicine prepared by this formula Thing good drug efficacy, instant effect, it is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Tool below in conjunction with the present invention Body embodiment is described in further detail:
Embodiment 1:
A kind of Chinese medicine composition treating diabetes, it is characterised in that each component of described Chinese medicine composition and mass parts thereof Ratio is as follows:
Rhizoma Anemarrhenae 200g, Rhizoma Alismatis 150g, Rhizoma Atractylodis Macrocephalae 120g, Rhizoma Atractylodis 120g, Fructus Gardeniae 170g, Radix Scrophulariae 200g, Rhizoma Coptidis 40g, Radix Salviae Miltiorrhizae 120g, river Rhizome of chuanxiong 90g, Pollen Typhae 90g, Herba Euphorbiae Humifusae 120g, Poria 200g, Radix Rehmanniae 250g.
Embodiment 2:
A kind of Chinese medicine composition treating diabetes, it is characterised in that each component of described Chinese medicine composition and mass parts thereof Ratio is as follows:
Rhizoma Anemarrhenae 230g, Rhizoma Alismatis 170g, Rhizoma Atractylodis Macrocephalae 140g, Rhizoma Atractylodis 140g, Fructus Gardeniae 200g, Radix Scrophulariae 230g, Rhizoma Coptidis 45g, Radix Salviae Miltiorrhizae 140g, river Rhizome of chuanxiong 105g, Pollen Typhae 105g, Herba Euphorbiae Humifusae 140g, Poria 230g, Radix Rehmanniae 280g.
Embodiment 3:
A kind of Chinese medicine composition treating diabetes, it is characterised in that each component of described Chinese medicine composition and mass parts thereof Ratio is as follows:
Rhizoma Anemarrhenae 260g, Rhizoma Alismatis 200g, Rhizoma Atractylodis Macrocephalae 160g, Rhizoma Atractylodis 160g, Fructus Gardeniae 220g, Radix Scrophulariae 260g, Rhizoma Coptidis 50g, Radix Salviae Miltiorrhizae 160g, river Rhizome of chuanxiong 120g, Pollen Typhae 120g, Herba Euphorbiae Humifusae 160g, Poria 260g, Radix Rehmanniae 320g.
Model case
Through clinical conditions diabetics totally 615 example, the age is 365 examples of more than 57 years old, only 250 examples be 57 years old with Under.The most normal 555 examples of blood glucose in 615 example patients, 60 effective examples, total effective rate reaches 100%.

Claims (3)

1. the Chinese medicine composition treating diabetes, it is characterised in that each component of described Chinese medicine composition and quality thereof Part ratio is as follows:
The Rhizoma Anemarrhenae 100~260g, Rhizoma Alismatis 100~200g, the Rhizoma Atractylodis Macrocephalae 80~160g, Rhizoma Atractylodis 80~160g, Fructus Gardeniae 100~220g, Radix Scrophulariae 150~260g, Rhizoma Coptidis 25~50g, Radix Salviae Miltiorrhizae 80~160g, Rhizoma Chuanxiong 50~120g, Pollen Typhae 50~120g, Herba Euphorbiae Humifusae 100~160g, Poria 150~260g, the Radix Rehmanniae 100~320g.
The Chinese medicine composition for the treatment of diabetes the most according to claim 1, it is characterised in that described Chinese medicine composition each Individual component and mass parts ratio thereof are as follows:
The Rhizoma Anemarrhenae 115~230g, Rhizoma Alismatis 115~170g, the Rhizoma Atractylodis Macrocephalae 90~140g, Rhizoma Atractylodis 90~140g, Fructus Gardeniae 115~200g, Radix Scrophulariae 170~230g, Rhizoma Coptidis 28~45g, Radix Salviae Miltiorrhizae 90~140g, Rhizoma Chuanxiong 60~105g, Pollen Typhae 60~105g, Herba Euphorbiae Humifusae 115~140g, Poria 180~230g, the Radix Rehmanniae 115~280g.
3. according to the Chinese medicine composition of the treatment diabetes described in claim 1 to 2, it is characterised in that described Chinese medicine composition Each component and mass parts ratio as follows:
Rhizoma Anemarrhenae 200g, Rhizoma Alismatis 150g, Rhizoma Atractylodis Macrocephalae 120g, Rhizoma Atractylodis 120g, Fructus Gardeniae 170g, Radix Scrophulariae 200g, Rhizoma Coptidis 40g, Radix Salviae Miltiorrhizae 120g, river Rhizome of chuanxiong 90g, Pollen Typhae 90g, Herba Euphorbiae Humifusae 120g, Poria 200g, Radix Rehmanniae 250g.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106924427A (en) * 2017-03-24 2017-07-07 成都海青生物科技有限公司 It is a kind of effectively to treat Chinese medicine composition of diabete and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106924427A (en) * 2017-03-24 2017-07-07 成都海青生物科技有限公司 It is a kind of effectively to treat Chinese medicine composition of diabete and preparation method thereof

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