CN107412309A - 一种蒲公英的冻干粉粒制备方法 - Google Patents

一种蒲公英的冻干粉粒制备方法 Download PDF

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CN107412309A
CN107412309A CN201710696309.2A CN201710696309A CN107412309A CN 107412309 A CN107412309 A CN 107412309A CN 201710696309 A CN201710696309 A CN 201710696309A CN 107412309 A CN107412309 A CN 107412309A
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高全平
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
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Abstract

一种蒲公英的冻干粉粒制备方法，所述的制备方法包括如下步骤：a）净制，在蒲公英新鲜料中，挑捡出杂质和腐烂叶片，用饮用水洗去泥沙杂质，再用纯净水漂洗；b）烫水杀青，用90—100℃的水煮2—5分钟，沥水摊凉；c）制浆，用打浆机制成浆液；d）冷冻干燥，用冷冻干燥机干燥至含水6%以下时取出；e）超低温粉碎，在零下10—30℃的环境下，粉碎成200目的超细粉；f）沸腾制粒，用沸腾制粒机并用纯净水作粘合剂、将超细粉制成颗粒；它具有制备方法简单，产量高，能够大面积推广应用，能够最大地保障产品的生物活性，提高有效成分的利用率，提高体内吸收率，制成的颗粒可以方便冲泡使用等特点。

Description

一种蒲公英的冻干粉粒制备方法
技术领域
本发明涉及的是一种蒲公英的冻干粉粒制备方法，属于药剂的冻干粉粒制备技术领域。
背景技术
蒲公英别名黄花地丁、婆婆丁、黄花郎等，菊科多年生草本植物，根圆锥状，表面棕褐色，皱缩，叶边缘有时候具波纹齿或羽状深裂，基部渐狭成叶柄，叶柄及主脉常带红紫色，花亭上部紫红色，密被蛛丝状白色长柔毛，头状花序，总苞钟状，廋果暗褐色，长寇毛白色，花果期4—10个月。
现有技术很少将蒲公英制成冻干粉的，仅仅有报道将蒲公英制成粉针制剂，但是粉针制剂大多应用在医学上，而且其采取蒲公英提取物作为制剂原料，制备方法复杂，产量少，无法大面积推广应用。
发明内容
本发明的目的在于克服现有技术存在的不足，而提供一种制备方法简单，产量高，能够大面积推广应用，能够最大地保障产品的生物活性，提高有效成分的利用率，提高体内吸收率，制成的颗粒可以方便冲泡使用的蒲公英的冻干粉粒制备方法。
本发明的目的是通过如下技术方案来完成的，一种蒲公英的冻干粉粒制备方法，所述的制备方法包括如下步骤：
a）净制，在蒲公英新鲜料中，挑捡出杂质和腐烂叶片，用饮用水洗去泥沙杂质，再用纯净水漂洗；
b）烫水杀青，用90—100℃的水煮2—5分钟，沥水摊凉；
c）制浆，用打浆机制成浆液；
d）冷冻干燥，用冷冻干燥机干燥至含水6%以下时取出；
e）超低温粉碎，在零下10—30℃的环境下，粉碎成200目的超细粉；
f）沸腾制粒，用沸腾制粒机并用纯净水作粘合剂、将超细粉制成颗粒。
作为优选；所述的步骤b），用95—100℃的水煮3—5分钟，稍有本品固有清香气溢出时捞起，沥水摊凉；
所述的步骤d），用冷冻干燥机干燥至含水5%以下时取出；
所述的步骤e），在零下20—30℃的环境下，粉碎成200目的超细粉。
本发明具有制备方法简单，产量高，能够大面积推广应用，能够最大地保障产品的生物活性，提高有效成分的利用率，提高体内吸收率，制成的颗粒可以方便冲泡使用等特点。
具体实施方式
下面将结合具体实施例对本发明作详细的介绍：本发明所述的一种蒲公英的冻干粉粒制备方法，所述的制备方法包括如下步骤：
a）净制，在蒲公英新鲜料中，挑捡出杂质和腐烂叶片，用饮用水洗去泥沙杂质，再用纯净水漂洗；
b）烫水杀青，用90—100℃的水煮2—5分钟，沥水摊凉；
c）制浆，用打浆机制成浆液；
d）冷冻干燥，用冷冻干燥机干燥至含水6%以下时取出；
e）超低温粉碎，在零下10—30℃的环境下，粉碎成200目的超细粉；
f）沸腾制粒，用沸腾制粒机并用纯净水作粘合剂、将超细粉制成颗粒。
本发明进一步的实施例是：本发明所述的一种蒲公英的冻干粉粒制备方法，所述的制备方法包括：
a）净制，选用新鲜全草的蒲公英原料，挑捡出杂质和腐烂叶片，用饮用水洗去泥沙杂质，再用纯净水漂洗；
b）烫水杀青，用95—100℃的水煮3—5分钟，稍有本品固有清香气溢出时捞起，沥水摊凉；
c）制浆，用打浆机制成浆液；
d）冷冻干燥，用冷冻干燥机干燥至含水5%以下时取出；
e）超低温粉碎，在零下20—30℃的环境下，粉碎成200目的超细粉；
f）沸腾制粒，用沸腾制粒机并用纯净水作粘合剂、将超细粉制成颗粒。
传统工艺是：浸出物照醇溶性浸出物测定法测定，用75%乙醇作溶剂，不得少于18.0%，含咖啡酸（C9H8O4）不得少于0.020%。
本发明所述的制备工艺是：浸出物照醇溶性浸出物测定法测定，用75%乙醇作溶剂，不得少于25.0%，含咖啡酸（C9H8O4）不得少于0.030%。

Claims (2)

1.一种蒲公英的冻干粉粒制备方法，其特征在于所述的制备方法包括如下步骤：
a）净制，在蒲公英新鲜料中，挑捡出杂质和腐烂叶片，用饮用水洗去泥沙杂质，再用纯净水漂洗；
b）烫水杀青，用90—100℃的水煮2—5分钟，沥水摊凉；
c）制浆，用打浆机制成浆液；
d）冷冻干燥，用冷冻干燥机干燥至含水6%以下时取出；
e）超低温粉碎，在零下10—30℃的环境下，粉碎成200目的超细粉；
f）沸腾制粒，用沸腾制粒机并用纯净水作粘合剂、将超细粉制成颗粒。
2.根据权利要求1所述的蒲公英的冻干粉粒制备方法，其特征在于：
所述的步骤a），选用新鲜全草的蒲公英原料；
所述的步骤b），用95—100℃的水煮3—5分钟，稍有本品固有清香气溢出时捞起，沥水摊凉；
所述的步骤d），用冷冻干燥机干燥至含水5%以下时取出；
所述的步骤e），在零下20—30℃的环境下，粉碎成200目的超细粉。
CN201710696309.2A 2017-08-15 2017-08-15 一种蒲公英的冻干粉粒制备方法 Pending CN107412309A (zh)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113925888A (zh) * 2021-11-10 2022-01-14 广西农业职业技术大学 一种蒲公英散剂的制备方法及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104413207A (zh) * 2013-08-27 2015-03-18 贝尔香精香料（上海）有限公司 一种青稞菊花茶饮品及其制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104413207A (zh) * 2013-08-27 2015-03-18 贝尔香精香料（上海）有限公司 一种青稞菊花茶饮品及其制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113925888A (zh) * 2021-11-10 2022-01-14 广西农业职业技术大学 一种蒲公英散剂的制备方法及其应用

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