CN107412055A - A kind of sun-proof plant residue composition and its application - Google Patents
A kind of sun-proof plant residue composition and its application Download PDFInfo
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- CN107412055A CN107412055A CN201710636004.2A CN201710636004A CN107412055A CN 107412055 A CN107412055 A CN 107412055A CN 201710636004 A CN201710636004 A CN 201710636004A CN 107412055 A CN107412055 A CN 107412055A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- Gerontology & Geriatric Medicine (AREA)
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Abstract
The invention discloses a kind of sun-proof plant residue composition and its application, the plant residue composition is made up of following parts by weight of component:Giant knotweed extracts 0.2 1.0 parts of slag, ginkgo leaf 0.3 0.7 parts of slag of extraction, radix scutellariae 0.1 0.8 parts of slag of extraction.Be applied in ultra light sun block lotion, to UVA UVB there is broad absorption effect, and with uvioresistant, anti-aging, the release of antiallergy medium and Bearberry Extract.In addition, the plant residue composition green natural, gentle non-stimulated.
Description
Technical field
The present invention relates to cosmetic field, and in particular to a kind of sun-proof plant residue composition and its application.
Background technology
With increasingly sharpening for environmental pollution, ozone layer is gradually thinning, and harm of the ultraviolet to the mankind increasingly aggravates.UVB
Wavelength is shorter, and penetration capacity is relatively weak, and it can only reach the epidermis of skin, but its energy is big, and can burn skin, make skin
There is pain, erythema, oedema, bubble in skin.UVA wavelength is longer, and penetration capacity is relatively strong, and it can penetrate the epidermis of skin
Layer, skin corium is reached, causes skin blackening, color spot occurs;Can also elasticity of skin be reduced, wrinkle occur, cause skin to occur
Too early aging phenomenon.UVA can not only cause the aging of skin, the formation of color spot, or even can trigger skin canceration.It is in addition, ultraviolet
Line also results in skin and produces free radical, and free radical can further speed up the aging of skin, the calmness of pigment.Some people can also go out
Existing light sensitivity scytitis reaction.Commercially available sunlight screening skin-protecting product UV absorption wavelength is single, multiplexing ultra light sun block lotion security is present
Problem and lack anti-oxidant, antianaphylactic defect, develop to UVA UVB there is broad absorption effect, and with anti-oxidant, anti-
The sunlight screening skin-protecting product of allergy multi-efficiency is following development trend.
The content of the invention
For prior art, it is an object of the invention to provide a kind of sun-proof plant residue composition and its application, and this is anti-
Shine plant residue composition to UVA UVB there is broad absorption effect, also anti-oxidant, antiallergy multi-efficiency, and safety, can
Lean on, have no side effect.
To achieve the above object, the present invention provides following technical scheme:
A kind of plant residue composition extracts slag by giant knotweed, ginkgo leaf extracts slag, radix scutellariae extraction slag forms, and described tiger
Cane extraction slag, ginkgo leaf extraction slag, the weight ratio of radix scutellariae extraction slag are (2-10):(3-7):(1-8).
Preferably, described giant knotweed extraction slag, ginkgo leaf extraction slag, the parts by weight of radix scutellariae extraction slag are as follows:
Giant knotweed extracts slag 0.2-1.0 parts
Ginkgo leaf extracts slag 0.3-0.7 parts
Radix scutellariae extracts slag 0.1-0.8 parts.
A kind of sun-proof plant residue composition is prepared as follows:By giant knotweed, ginkgo leaf, scullcap plant raw material by carrying
Take the residue after utilizing to be dried, be then comminuted into 10-15 mesh, and mix in above-mentioned ratio.
Further, residue of the described plant material after extraction and application refer to plant material by alcohol extracting, water extraction,
Left residue after one or more techniques extraction in oil immersion formulation, supercritical carbon dioxide extraction method.
Present invention also offers a kind of sun-proof plant residue to prepare the application of cosmetics, and the cosmetics are sunscreen
Liquid.
Further, described emulsion includes the component of following parts by weight:
Above-mentioned sun-proof plant residue composition 0.6-2.5 parts, dimethyl silicone polymer 2-10 parts, isopropyl palmitate 3-
10 parts, cetearyl alcohol acid alcohol 1-5 parts, coco group glucoside 1-5 parts, stearine 1-5 parts, glycerine 5-10 parts, the third two
Alcohol 1-3 parts, EDETATE SODIUM 0.01-0.1 parts, titanium dioxide 2-5 parts, golden yellow camomile extract 0.1-0.8 parts, aloe extract
0.1-0.6 parts, triethanolamine 0.1-0.3 parts, Phenoxyethanol 0.1-0.5 parts, essence 0.02-0.1 parts, deionized water surplus.
Make following introduce to main composition of the present invention:
Giant knotweed, bitter cane, tiger cane, radix dactylicapni, yellow garden burnet etc. are commonly called as, are polygonaceae plant Polygonum herbaceos perennial giant knotweed
Dry rhizome and root, be China's traditional Chinese medicine, there is expelling wind and removing dampness, expelling phlegm and arresting coughing, clearing heat and detoxicating, promoting blood circulation and removing blood stasis and other effects,
It is usually used in treating jaundice with damp-heat pathogen, cough with lung heat, scald, traumatic injury etc..Modern pharmacology experiment also fully proves that giant knotweed has
Have and expand the effect such as blood vessel, Hemorrhagic shock, reducing blood lipid, antiviral, anti-inflammatory, antibacterial.The composition stronger containing ultraviolet is absorbed in giant knotweed,
There is relatively strong sun-proof ability, be the natural plants with wide spectrum anti-sunlight function.
Ginkgo is Ginkgoaceae Ginkgo deciduous tree for many years, alias Gong Sunshu, duck's foot tree, maidenhair tree, is also in the world most
One of ancient rare tree species.Ginkgo leaf is derived from the dried leaf of ginkgo, when autumn leaf is still green collection and when dry.Its moral character
It is flat, it is bitter, puckery, sweet;The thoughts of returning home, lung channel;Have the effect of to relieving asthma, astringe the lung, relieve pain, activating blood circulation and dispersing blood clots.Ginkgo biloba p.e is mainly effective
Composition is flavonoids, terpene and organic acid;With improvement microcirculation, antiplatelet activity factor, anti-oxidant removing and suppression
The pharmacological action such as oxygen radical, anti-inflammation, expansion cardiovascular and cerebrovascular, antiviral.Flavones contained by ginkgo biloba p.e is strong
Oxygen free radical scavenger, Skin Cell can be protected not influenceed by oxygen radical over oxidation, so as to extend Skin Cell
In the life-span, strengthen the ability of its anti-aging.
Radix scutellariae bitter is cold in nature, and energy heat-clearing and damp-drying drug, purging intense heat and detonicating, main component are scutelloside etc..Radix scutellariae is gone through China is medicinal
History is long, and baicalein and scutelloside are the main actives that radix scutellariae plays effect.Baicalein and scutelloside have antibacterial disease-resistant
Poison, scavenging activated oxygen, anti-oxidant, antipyretic, analgesia, anti-inflammatory, it is antitumor, protection cardiovascular and cerebrovascular and neuron, liver protection, prevention or
Treat the effect modern pharmacological research such as diabetes and its complication and find that radix scutellariae and its active ingredient scutelloside have sun-proof work
With.In terms of the anti-sunlight function of radix scutellariae is embodied in light-protection, it can especially mitigate long wave ultraviolet (UVA), ultraviolet B radiation (UVB)
To the damaging action of Skin Cell.Scutelloside can accelerate to induce the formation of photoproduct, resist oxidative stress, reduce the table of photoproduct
Reach, play anti-oxidant anti-sunlight function of Denging, and ultraviolet energy can be absorbed, suppress fibroblasts to secrete relevant inflammatory factors, with
Alleviate cell senescence.Scutelloside has antiultraviolet, antiallergy, suppress melanin and anti-inflammatory is antibacterial and other effects, protects skin not
Encroached on by free radical, extend the Skin Cell life-span, enhancing anti-aging ability and suppression light aging.
Compared with prior art, it is the device have the advantages that as follows:(1) natural plants residue of the invention has anti-
Ultraviolet, anti-aging, the release of antiallergy medium and Bearberry Extract, can also repair skin while ultraviolet is resisted, reduce
Erythema, keratinization, calcination etc. influence caused by excessive ultraviolet irradiation, while also have low irritant.(2) radix scutellariae extraction slag is inhaled
Ultraviolet energy is received, damaging action of the ultraviolet to Skin Cell can be mitigated, accelerates the formation of induction photoproduct, resistance oxidation
Stress, anti-oxidant anti-sunlight function of Denging is played in the expression for reducing photoproduct, and the ability of ultraviolet is absorbed with reference to giant knotweed extraction slag, is more had
The absorption ultraviolet of effect;Then slag is extracted by ginkgo leaf and radix scutellariae extracts the effect of slag removes free radical, suppress melanin
Produce, protect skin not encroached on by free radical;Finally suppress the release of Anaphylactic mediator using radix scutellariae extraction slag antiallergy effect,
Promote skin metabolism, multiple mechanisms combine and play sun-proof effect.(3) sun-proof plant residue composition of the invention, it is
Rear remaining residue is extracted by plant to combine, mainly using also there being the distinctive active component of its raw material in residue,
Act synergistically to reach the effect of sun-proof.These residues are effectively utilized, turns waste into wealth, reduces production cost, improve plant
The utilization rate of raw material, while contribute to environmental protection.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated:
The ultra light sun block lotion embodiment 1~5 of the present invention is formulated, and is shown in Table 1.
Table 1
A kind of sun-proof plant residue composition is prepared as follows:
The residue of giant knotweed, ginkgo leaf, scullcap plant raw material after extraction and application is dried, is then comminuted into 10-
15 mesh, and mixed in above-mentioned ratio.
Comparative example 1:
Giant knotweed extraction slag is not added in difference with embodiment 3 only, and remaining each material addition, conditions and technology of preparation is not
Change.
Comparative example 2:
Ginkgo leaf extraction slag is not added in difference with embodiment 3 only, remaining each material addition, and conditions and technology of preparation is equal
Do not change.
Comparative example 3:
Radix scutellariae extraction slag is not added in difference with embodiment 3 only, and remaining each material addition, conditions and technology of preparation is not
Change.
Comparative example 4:
Compared with Example 3, giant knotweed extraction slag, ginkgo leaf extraction slag, radix scutellariae extraction slag do not add, and remaining each material adds
Dosage, conditions and technology of preparation do not change still.
Uvioresistant efficacy validation:
When irradiating keratinocyte with ultraviolet, active oxygen is produced in cell.In order to artificially induce such case, by people
Normal keratinocyte, i.e. Hacat cells (Korea Cell Line Bank), are inoculated into each hole of 48 hole microplates, density
For 1x104 cells/wells, and cultivated 24 hours at 37 DEG C in DMEM culture mediums (Sigama, USA).Shone with ultraviolet (UVB)
The cell of culture is penetrated, then the sample of embodiment 1~5 and comparative example 1~4 is added in the culture in each hole.After 24 hours,
The activity of cell is analyzed by MTT methods of inspection.
Table 2
The composition one side energy trophocyte of the present invention, promotes the metabolism of cell, together it can be seen from upper table 2
When contribute to cell to breed, repair damage;On the other hand ultraviolet can be reduced damage or dead is caused to normal cell, significantly
Reduce the cell mortality under ultraviolet irradiation.
The base in comparative example 4 is can be seen that from the cell mortality of embodiment, comparative example 1~3, comparative example 4 and sterilized water
Though this ultra light sun block lotion has certain uvioresistant function, unobvious;And comparative example 1~3 all each lacks one in composition
It is divided into point, has certain lifting compared with the anti-uv-ray of the basic emulsion of comparative example 4, but still very high cell death damage
Rate;Referring finally to embodiment, embodiment items have obvious difference than comparative example and sterilized water, illustrate to be highly resistant to ultraviolet
Damage to cell, damage of the ultraviolet to skin under sunlight can be reduced.
Anti-oxidation efficacy is verified:
Scavenging activity using Fenton repercussion studies this product to OH.It is separately added into reaction system
0.75mmol/L Phen 1.00ml, 0.150mol/L PBS (pH7.4) 1.50ml, after fully mixing, add
0.75mmol/L FeSO4Solution 1.00ml, is mixed immediately after adding.Then the implementation of various concentrations is added into reaction system again
Example or comparative example finished product 1.00ml, mix.Negative control pipe and normal pipe separately are set, not sample adding liquid.In each pipe respectively
Add 0.01% H2O2Solution 1.00ml, normal pipe are not added with H2O2Solution, volume is supplemented with isometric distilled water.In 37 DEG C of water
In bath;30min is incubated, determines A536Do 3 parallel laboratory tests.
OH clearance rates (%)=[(A2- A1)/(A0- A1)] × 100%
Wherein, A0For normal pipe light absorption value, A1For negative control pipe light absorption value, A2To be loaded pipe light absorption value.
Reacted using Fenton, scavenging action of the detection this product to hydroxyl radical free radical, its result is as shown in table 3.
Table 3
As can be seen that this product shows the activity of certain scavenging hydroxyl, and activity and the group in the present invention
Compound is relevant.Comparative example 4 and other comparative examples are contrasted into the samples of latex it can be found that when this patent composition does not add all
For the un-added basic emulsion sample of each composition of composition, have it is obvious remove free radical antioxidation, but with implementation
Example contrast is known that its antioxidation effect is incomplete, when each composition is compounded with special ratios in composition, can play
Go out inoxidizability more more preferable than monomer.
Antiallergy efficacy validation:
Selection includes the class skin attribute crowd of neutrality, oiliness, dryness, responsive type, mixed type etc. 5 person that serves as product beta test,
Each 50 people is divided into one group.
Equivalent sample liquid is smeared in both hands arm with comparative example 4 using embodiment 3 respectively sooner or later daily, after one month
Carry out questionnaire type investigation.
Respectively from investigation product effect following aspects:Allergy, sun-proof, tight, overall use feeling, the result of embodiment
4 are shown in Table, comparative example the results are shown in Table 5
Table 4
Table 5
Contrast table 4 and the embodiment of table 53 are evaluated with the sampling person of comparative example 4, it is found that the complete addition present invention
Its whole structure of the embodiment 3 of composition, including antiallergy, it is sun-proof, be better than with rear tight etc. impression and be not added with group
The comparative example 4 of compound, illustrate that this product composition can effectively improve user of the common sunscreen emulsion in antiallergy, sun-proof etc.
Impression.
Above example is merely to illustrate embodiment of the present invention, does not have any formal limit to the present invention
System;It is any to be engaged in professional and technical personnel, all have the ability using the technology contents having revealed that, some are made to it and changes or repaiies
Decorations, turn into the equivalent embodiment of equivalent variations.According to the technology of the present invention essence, simply modification, equivalent variations are carried out to the present invention
With modification, belong in the range of technical solution of the present invention.
Claims (8)
1. a kind of sun-proof plant residue composition, it is characterised in that described plant residue composition extracts slag, ginkgo by giant knotweed
Leaf extraction slag, radix scutellariae extraction slag composition.
A kind of 2. sun-proof plant residue composition according to claim 1, it is characterised in that described giant knotweed extraction slag,
Ginkgo leaf extraction slag, the weight ratio of radix scutellariae extraction slag are (2-10):(3-7):(1-8).
A kind of 3. sun-proof plant residue composition according to claim 1 or 2, it is characterised in that described giant knotweed extraction
Slag, ginkgo leaf extraction slag, the parts by weight of radix scutellariae extraction slag are as follows:
Giant knotweed extracts slag 0.2-1.0 parts
Ginkgo leaf extracts slag 0.3-0.7 parts
Radix scutellariae extracts slag 0.1-0.8 parts.
4. a kind of plant residue composition according to claims require any one of 1-3, it is characterised in that described
Sun-proof plant residue composition is prepared as follows:Giant knotweed, ginkgo leaf, scullcap plant raw material is residual after extraction and application
Slag is dried, and is then comminuted into 10-15 mesh, and mix in above-mentioned ratio.
5. according to the sun-proof plant residue described in claim any one of 1-4, it is characterised in that described plant material is by carrying
The residue after utilizing is taken to refer to plant material by one kind in alcohol extracting, water extraction, oil immersion formulation, supercritical carbon dioxide extraction method
Or the residue left by after kinds of processes extraction.
6. a kind of sun-proof plant residue according to claim any one of 1-5 is preparing the application of cosmetics.
7. application according to claim 6, it is characterised in that described cosmetics are ultra light sun block lotion.
8. a kind of ultra light sun block lotion, it is characterised in that described emulsion includes the component of following parts by weight:As claimed in claim 1
Sun-proof plant residue composition 0.6-2.5 parts, dimethyl silicone polymer 2-10 parts, isopropyl palmitate 3-10 parts, spermaceti it is hard
Resin acid alcohol 1-5 parts, coco group glucoside 1-5 parts, stearine 1-5 parts, glycerine 5-10 parts, propane diols 1-3 parts, EDTA
Disodium 0.01-0.1 parts, titanium dioxide 2-5 parts, golden yellow camomile extract 0.1-0.8 parts, aloe extract 0.1-0.6 parts, three
Monoethanolamine 0.1-0.3 parts, Phenoxyethanol 0.1-0.5 parts, essence 0.02-0.1 parts, deionized water surplus.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109172445A (en) * | 2018-09-27 | 2019-01-11 | 广州航美化妆品有限公司 | Whitening maintenance cream |
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CN103800239A (en) * | 2014-02-18 | 2014-05-21 | 广州中医药大学科技产业园有限公司 | Sunscreen lotion and preparation method thereof |
CN106727150A (en) * | 2017-01-04 | 2017-05-31 | 广州聚澜健康产业研究院有限公司 | A kind of sun-proof skin care cosmetic composition and its application |
-
2017
- 2017-07-28 CN CN201710636004.2A patent/CN107412055A/en not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103800239A (en) * | 2014-02-18 | 2014-05-21 | 广州中医药大学科技产业园有限公司 | Sunscreen lotion and preparation method thereof |
CN106727150A (en) * | 2017-01-04 | 2017-05-31 | 广州聚澜健康产业研究院有限公司 | A kind of sun-proof skin care cosmetic composition and its application |
Non-Patent Citations (2)
Title |
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刘利萍 主编: "《实用美容药物基础》", 31 August 2012, 重庆大学出版社 * |
白建华 等: "虎杖中防晒成分的提取与脱色研究", 《光谱实验室》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109172445A (en) * | 2018-09-27 | 2019-01-11 | 广州航美化妆品有限公司 | Whitening maintenance cream |
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