CN106860118A - A kind of anti-aging face cream - Google Patents
A kind of anti-aging face cream Download PDFInfo
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- CN106860118A CN106860118A CN201710187740.4A CN201710187740A CN106860118A CN 106860118 A CN106860118 A CN 106860118A CN 201710187740 A CN201710187740 A CN 201710187740A CN 106860118 A CN106860118 A CN 106860118A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- Gerontology & Geriatric Medicine (AREA)
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- Cosmetics (AREA)
Abstract
The present invention discloses a kind of anti-aging face cream, and plant composition includes following components by weight in anti-aging face cream:0.02 0.5 parts of 0.05 0.8 parts of HUOXUEDAN extract of hair, 0.02 0.5 parts of purple ball algae extract and purple yu-lan (Magnolia liliflora) flower extract.Instant invention overcomes the shortcoming of anti-aging face cream single effect, add hair HUOXUEDAN extract, purple ball algae extract and purple yu-lan (Magnolia liliflora) flower extract, the synergy between component is given full play to, composition good stability, so that anti-aging face cream not only has good anti-aging effects, replenishing water and preserving moisture and certain radiation-proof effect are also equipped with.
Description
Technical field
The present invention relates to cosmetic field, and in particular to a kind of anti-aging face cream.
Background technology
Aging is inevitable law of nature in life process, and skin is used as first barrier of human body, during skin
Moment is carved all in aging, aging, and its elasticity is slowly reduced, and thin down, it is more and more fragile and lax, what is given people is directly perceived
Impression is exactly wrinkle long.Skin aging typically has natural aging and light aging.The former refers mainly to age, by body
It is aging that such as heredity, gravity, endocrine and the immunologic function for existing can not resist that factor causes;The latter is mainly due to ultraviolet
Effect, accelerate the process of naturally-aged, and a series of environmental exposures such as climate change and environmental pollution are to the light of skin
It is aging also to have directly influence.The approach of anti-aging, mainly includes:Protect the skin from external environment stimulation;Scavenger-cell
Interior unnecessary free radical;Skin Cell is repaired and is supplemented the nutrients.Skin anti-aging is to prevent skin because the time elapses
There is the gradually function of property and organic moving back to sexually revise, show as preventing wrinkle, drying, play bits, lax and color spot.It is anti-ageing
Aging cosmetic is exactly to realize the cosmetics of senile-resistant efficacy, is one of important effect type cosmetics.
What present anti-aging cosmetics had has used the strong industry of inoxidizability to reach good anti-aging effects
Composition, instant effect in short-term, but for a long time using very big to harm;Some anti-aging cosmetics add vitamins antioxygen
Agent, but this kind of antioxidant less stable.The natural plant extracts that will have senile-resistant efficacy are made the group of good stability
Compound is added in cosmetics, assigns product good senile-resistant efficacy, is a trend of anti-aging product.
With the development and the raising of standard of living of society, requirement of the people to cosmetics also more and more higher is particularly produced
The security of product, it is desirable to which anti-aging is made up has good anti-aging effects, while being natural safe and non-stimulating.
The content of the invention
Based on this, it is an object of the invention to provide a kind of anti-aging face cream, the face cream causes that skin becomes delicate, light
It is sliding, flexible, with excellent anti-aging effects.
The present invention is realized by following scheme:
A kind of anti-aging face cream contains the plant composition that mass percent is 0.09-1.8%, and the plant composition contains
There is each component of following weight portion:HUOXUEDAN extract 0.05-0.8 parts, 0.02-0.5 parts of purple ball algae extract and Qarnet orchid
Extract 0.02-0.5 parts, the HUOXUEDAN extract in plant composition, the weight of purple ball algae extract and purple yu-lan (Magnolia liliflora) flower extract
It is (5~8) that amount part is compared:(2~5):(3~5).
The preparation method of the HUOXUEDAN extract is:Blood circulation promoting pill is cleaned up, is baked to crush 40~60 mesh
Sieve, 2h is extracted with ethanol, and gained extract solution removes ethanol through vacuum rotary steam again.
The preparation method of the purple ball algae extract is:Purple ball algae dry algae powder is taken, is placed in 4% sodium hydroxide solution, instead
Supernatant and frond fragment are collected in multiple freeze thawing three times, centrifugation respectively, and frond fragment is placed in 3~4h of heating in boiling water bath, filters
Filtrate, merging filtrate and supernatant, water-bath concentration, the absolute ethyl alcohol of three times volume is added toward the concentrate of above-mentioned collection, from
The heart, taking precipitate redissolves sediment water, with Sevage method removing proteins, water-bath concentration, freeze-drying.
The preparation method of the purple yu-lan (Magnolia liliflora) flower extract is:Qarnet orchid is dried and crushed into powder, in apparatus,Soxhlet's
Middle alcohol reflux extracts 12~13h, collects extract solution, concentrated under reduced pressure with Rotary Evaporators.
A kind of anti-aging face cream includes the component of following mass percent:
A kind of preparation method of anti-aging face cream face cream is comprised the following steps:
(1) by stearine/PEG-100 stearates, caprylic/capric triglyceride, Dormant oils, vaseline, saualane,
Dimethyl silicone polymer, polyoxyethylene cetyl base stearyl bis ether, methyl hydroxybenzoate, Nipasol mixing constitute oil phase and add oil phase
Pot, is heated with stirring to 75-85 DEG C, waits all components to be incubated after dissolving, and A phases are obtained;
(2) glycerine, allantoin, propane diols, Carbomer, carbonic acid dioctyl ester and deionized water are mixed into composition water and is added to water
Phase pot, is heated with stirring to 70-85 DEG C, and insulation 15-30min makes it fully dissolve, and B phases are obtained;
(3) A phases, B phases are pumped into emulsification pot successively, homogeneous 5-15min, stir speed (S.S.) is 2000-4000r/min,
Then insulated and stirred 15-45min, stir speed (S.S.) is 30-50r/min;40-45 DEG C is cooled to, plant composition, fourth hydroxyl first is added
Benzene, stirs.
Make following introduction to the plant composition in anti-aging face cream of the present invention:
Blood circulation promoting pill also known as Longtube Ground Ivy Herb, copper coin grass, it is deep disappear, money peppermint, perennial herb.HUOXUEDAN extract is rich in Huang
Letones, blood circulation promoting pill general flavone has very strong scavenging action to oxygen radical and hydroxy radical, and Scavenging activity has with concentration
Obvious dependence.Flavone compound has very strong antioxidation, can be by suppressing and removing free radical and activity
Oxygen avoids oxidative damage, reaches anti-aging effects.
Purple ball algae is Zi Qiu algaes section, Porphyridium, fresh water algae plant.Contain up to 50% algae in purple ball algae extract
Biliprotein, phycobniliprotein is having stronger absorption decomposition to the larger radiant light section of human body skin injury, by absorbing
Electromagnetic radiation, converts energy, and the repair system of active cell eliminates or reduces the anion that radiation is produced on DNA, reaches anti-
The mesh ground of electromagnetic radiation is protected, so as to reduce injury of the electromagnetic radiation to human body skin.
Purple yu-lan (Magnolia liliflora) also known as lily magnolia, the flower bud of lily magnolia, marlinspike, prestige spring, Magnoliaceae Magnolia.Flavonoids is rich in purple yu-lan (Magnolia liliflora) flower extract
Material, has certain scavenging action to free radical, also with the effect that anti-inflammatory analgesic is sterilized.
Compared with prior art, the method have the advantages that
(1) anti-aging face cream of the present invention with the addition of HUOXUEDAN extract, purple ball algae extract and purple yu-lan (Magnolia liliflora) flower extract, press
Arranged in pairs or groups according to special ratios, the Flavonoid substances that HUOXUEDAN extract contains have very strong to oxygen radical and hydroxy radical
Scavenging action, oxidative damage is avoided by suppressing and removing free radical and active oxygen, reaches anti-aging effects;The purple ball algae of compounding
Distinctive phycobniliprotein in extract, is absorbed and larger radiant light is injured to human body skin, and the repair system of active cell is reduced
Injury of the electromagnetic radiation to human body skin;Flavonoid substances in compounding purple yu-lan (Magnolia liliflora) flower extract, sterilized with anti-inflammatory analgesic
Effect;Three reaches the effect of Synergistic by rational proportion, skin is become smooth, delicate, glossy and is rich in bullet
Property, also there is radiation proof function while with excellent anti-aging effects.
(2) present invention compounding addition dimethyl silicone polymer and saualane, great cunning is soft and silk-like handle, and forms film and exist
On skin, clearly not glutinous greasy, moistening effect is excellent.
Specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
The following component title occurred in text is INCI (Internation Nomenclaure Cosmetic
Ingredent, i.e. international cosmetic raw material name institute to regulation title, including:Caprylic/capric triglyceride, glycerine
Stearate/PEG-100 stearates.
The anti-aging face cream formula of the present invention of embodiment 1~5 is shown in Table one
Table one
Anti-aging face cream preparation method is comprised the following steps described in embodiment 1~5:By stearine/PEG-100
Stearate, caprylic/capric triglyceride, Dormant oils, vaseline, saualane, dimethyl silicone polymer, polyoxyethylene cetyl base are stearic
Base bis ether, methyl hydroxybenzoate, Nipasol mixing constitute oil phase and add oil phase pot, are heated with stirring to 80 DEG C, wait all components to dissolve
After be incubated, A phases are obtained;Glycerine, allantoin, propane diols, Carbomer, carbonic acid dioctyl ester and deionized water are mixed into composition water to be added
Enter water phase pot, be heated with stirring to 80 DEG C, insulation 30min makes it fully dissolve, and B phases are obtained;A phases, B phases are pumped into emulsification successively
In pot, homogeneous 15min, stir speed (S.S.) is 3000r/min, then insulated and stirred 30min, and stir speed (S.S.) is 40r/min;It is cooled to
40 DEG C, plant composition, Butylated Hydroxytoluene are added, stirred, obtain anti-aging face cream.
Comparative example 1
It is not add HUOXUEDAN extract with the difference of embodiment 1, other preparation conditions and method are same as Example 1.
Comparative example 2
It is not add purple ball algae extract with the difference of embodiment 1, other preparation conditions and method are same as Example 1.
Comparative example 3
It is not add purple yu-lan (Magnolia liliflora) flower extract with the difference of embodiment 1, other preparation conditions and method and the phase of embodiment 1
Together.
Comparative example 4
It is to add 1.9 parts of plant composition with the difference of embodiment 1, other preparation conditions and method are same as Example 1.
Comparative example 5
It is to add 0.08 part of plant composition, other preparation conditions and method and the phase of embodiment 1 with the difference of embodiment 1
Together.
Comparative example 6
It is not add plant composition with the difference of embodiment 1, other preparation conditions and method are same as Example 1.
Senile-resistant efficacy is verified:
Detection results on probation are carried out to product prepared by embodiment 1-5 and comparative example 1-6, while being declared with a commercially available
Face cream with good senile-resistant efficacy is control group.Test object:Each experimental group is 20 women (35-50 Sui);Test
Region:Wrinkles on one's forehead and crows feet area;Use:Twice daily, persistently use 6 weeks;Test event:Humidity of skin, skin are soft
Degree,
Skin elasticity.Result on trial refers to table two.
Table two
Obvious number is improved by the visible humidity of skin of embodiment 1~5 of table two, the soft degree of skin and skin elasticity substantially many
In comparative example 1~6 and control group, illustrate that anti-aging face cream of the present invention is significantly improved skin, the effect of delaying senility, contrast
The soft degree of the humidity of skin of example 4 and 5, skin and skin elasticity improve number and are significantly lower than embodiment, illustrate anti-aging face of the present invention
Plant extracts component span is better than other spans in frost;The humidity of skin of comparative example 6 is obviously improved 5 people, and skin is tender
Slippery is obviously improved 6 people, and skin elasticity is obviously improved 7 people, hence it is evident that less than other embodiment and comparative example, illustrates that the present invention is anti-ageing
Principle active component is plant composition in old face cream;The anti-aging face cream of comparative example 1 does not add HUOXUEDAN extract, its skin
The soft degree of humidity, skin and skin elasticity improve obvious number and are respectively 8 people, 7 people and 8 people, hence it is evident that less than the people of embodiment 1
Number;Comparative example 2 and 3 is respectively and is not added with purple ball algae extract and purple yu-lan (Magnolia liliflora) flower extract, the soft degree of its humidity of skin, skin and
Skin elasticity improves obvious number and is significantly lower than embodiment 1, and comparative example 1~3 contrasts visible anti-in the present invention with embodiment 1
In aging face cream, HUOXUEDAN extract, purple ball algae extract and purple yu-lan (Magnolia liliflora) flower extract extract Synergistic.
Anti-oxidation efficacy is verified:
Method and apparatus
Plant composition;95% ethanol (Chemical Reagent Co., Ltd., Sinopharm Group);(Tokyo is melted into strain formula meeting to DPPH
Society, analyzes pure);AB204-E electronic analytical balances (METTLE TOLEDO);UV-1600 ultraviolet specrophotometers (METTLE
TOLEDO)。
Determined with spectrophotometer method, plus the decline that OD514 absorbs after antioxidant or plant composition extract solution is represented
It eliminates ability to organic free radical.DPPH is first dissolved with a small amount of ethanol solution, and is configured to 1 × 10 with 10% ethanol-4mol/L
Solution, keep in dark place.Take 2molDPPH solution, add 2mL plant composition extract solutions to be sufficiently mixed, after 30 minutes
514nm (maximum absorption wave strong point) determines its OD514. and is to remove plant composition extraction liquid measure needed for DPPH50% i.e. IC50
Inoxidizability index.Clearance rate P is calculated and can be used following formula:P=[A0-(Ai-Aj)]/A0
In formula, A0The absorbance of=2mLDPPH solution+2mL solution;Ai=2mLDPPH solution+2mL the embodiment of the present invention 1
The absorbance of plant composition extract solution;AjThe extinction of the plant composition extract solution+2mL solvents of=2mL embodiment of the present invention 1
Degree.Result shows that the external i.e. plant composition extract solutions needed for IC50 of DPPH free radicals (1 × 10-4mol/L) 50% of removing are
0.732g。
The plant composition that the present invention is provided has prominent external Scavenging ability, with anti-oxidant well and
The performance of delay skin aging.
In a word, presently preferred embodiments of the present invention, all equalizations made according to scope of the present invention patent be the foregoing is only
Change and modification, should all belong to the covering scope of patent of the present invention.
Claims (9)
1. a kind of anti-aging face cream, it is characterised in that the face cream includes that mass percent is the plant society of 0.09-1.8%
Thing;
Wherein, plant composition is HUOXUEDAN extract, the mixture of purple ball algae extract and purple yu-lan (Magnolia liliflora) flower extract.
2. according to a kind of anti-aging face cream described in claim 1, it is characterised in that the weight portion of the plant composition is:It is living
0.02-0.5 parts of 0.05-0.8 parts of extract of blood pellet, 0.02-0.5 parts of purple ball algae extract and purple yu-lan (Magnolia liliflora) flower extract.
3. a kind of anti-aging face cream according to claim 1, it is characterised in that the HUOXUEDAN extract, purple ball algae carries
The weight part ratio for taking thing and purple yu-lan (Magnolia liliflora) flower extract is (5~8):(2~5):(3~5).
4. a kind of anti-aging face cream according to claim 1, it is characterised in that the preparation method of the HUOXUEDAN extract
For:Blood circulation promoting pill is cleaned up, is baked to crush 40~60 mesh sieves, 2h is extracted with ethanol, gained extract solution is again through decompression
Revolving removes ethanol.
5. a kind of anti-aging face cream according to claim 1, it is characterised in that the preparation method of the purple ball algae extract
For:Purple ball algae dry algae powder is taken, is placed in 4% sodium hydroxide solution, supernatant and algae are collected in multigelation three times, centrifugation respectively
Body fragment, frond fragment is placed in boiling water bath 3~4h of heating, filters to get filtrate, merging filtrate and supernatant, and water-bath concentration is past
The absolute ethyl alcohol of three times volume, centrifugation, taking precipitate is added to redissolve sediment water in the concentrate of above-mentioned collection, with
Sevage method removing proteins, water-bath concentration, freeze-drying.
6. a kind of anti-aging face cream according to claim 1, it is characterised in that the preparation side of the purple yu-lan (Magnolia liliflora) flower extract
Method is:Qarnet orchid is dried and crushed into powder, 12~13h is extracted with alcohol reflux in apparatus,Soxhlet's, collect extract solution,
It is concentrated under reduced pressure with Rotary Evaporators.
7. a kind of anti-aging face cream according to claim 1, it is characterised in that described face cream also includes following quality hundred
Divide the component of ratio:
8. a kind of anti-aging face cream according to claim 1, it is characterised in that the face cream also includes deionized water.
9. a kind of anti-aging face cream according to any one of claim 1~7, it is characterised in that the preparation side of the face cream
Method is comprised the following steps:
(1) by stearine/PEG-100 stearates, caprylic/capric triglyceride, Dormant oils, vaseline, saualane, poly- two
Methylsiloxane, polyoxyethylene cetyl base stearyl bis ether, methyl hydroxybenzoate, Nipasol mixing constitute oil phase and add oil phase pot,
75-85 DEG C is heated with stirring to, waits all components to be incubated after dissolving, A phases are obtained;
(2) glycerine, allantoin, propane diols, Carbomer, carbonic acid dioctyl ester and deionized water are mixed into composition water and is added to water phase
Pot, is heated with stirring to 70-85 DEG C, and insulation 15-30min makes it fully dissolve, and B phases are obtained;
(3) A phases, B phases are pumped into emulsification pot successively, homogeneous 5-15min, stir speed (S.S.) is 2000-4000r/min, then
Insulated and stirred 15-45min, stir speed (S.S.) is 30-50r/min;40-45 DEG C is cooled to, plant as claimed in claim 1 is added
Composition, Butylated Hydroxytoluene, stir.
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CN107411997A (en) * | 2017-06-26 | 2017-12-01 | 上海新高姿化妆品有限公司 | A kind of anti-aging face cream composition |
CN107898694A (en) * | 2017-12-07 | 2018-04-13 | 广州赛莱拉干细胞科技股份有限公司 | A kind of anti-aging composition and contain said composition cosmetics |
CN114886813A (en) * | 2022-05-27 | 2022-08-12 | 广州环亚化妆品科技股份有限公司 | Anti-aging plant extract composition and preparation method and application thereof |
CN115054550A (en) * | 2022-07-05 | 2022-09-16 | 中南大学 | Composite face cream, preparation method thereof and application thereof in skin care |
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CN115054550A (en) * | 2022-07-05 | 2022-09-16 | 中南大学 | Composite face cream, preparation method thereof and application thereof in skin care |
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