CN106074198A - Propolis ointment and preparation method thereof - Google Patents

Propolis ointment and preparation method thereof Download PDF

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Publication number
CN106074198A
CN106074198A CN201610665542.XA CN201610665542A CN106074198A CN 106074198 A CN106074198 A CN 106074198A CN 201610665542 A CN201610665542 A CN 201610665542A CN 106074198 A CN106074198 A CN 106074198A
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CN
China
Prior art keywords
extract
propolis
ointment
propolis ointment
solution
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CN201610665542.XA
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Chinese (zh)
Inventor
张守风
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Shandong Mystery Season Biotechnology Co Ltd
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Shandong Mystery Season Biotechnology Co Ltd
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Priority to CN201610665542.XA priority Critical patent/CN106074198A/en
Publication of CN106074198A publication Critical patent/CN106074198A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8129Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers or esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers, e.g. polyvinylmethylether
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Abstract

The invention discloses a kind of propolis ointment, propolis extract including 3~8 weight portions, the Mel extract of 1~5 weight portions, the aliphatic alcohols material of 30~45 weight portions, the plant extract of 5~15 weight portions, the vegetable oil of 3~8 weight portions, the vitamin of 0.4~1 weight portion, the trehalose of 0.5~3 weight portions, the methyl hydroxybenzoate of 0.05~0.2 weight portion, the DMDM Hydantoin of 0.1~0.5 weight portion, the water of 30~50 weight portions.The propolis ointment that the present invention provides, there is typical liquid crystal structure as carrier by the propolis ointment using propolis extract, Mel extract, aliphatic alcohols material, plant extract, vegetable oil, vitamin, trehalose, methyl hydroxybenzoate, DMDM Hydantoin to prepare, it is prone to infiltration, effective ingredient continuous action 24 hours, effect is lasting, and effect is obvious.Further, skin will not be damaged by the propolis ointment of the present invention, can be used for hand and body skin and arthralgia surface, is possible not only to slow down effect of pain and also whitening Antiageing effect, but also can play good therapeutical effect.

Description

Propolis ointment and preparation method thereof
Technical field
The present invention relates to skin care field, particularly relate to a kind of propolis ointment and preparation method thereof.
Background technology
Facial skin can because external environment, improper diet, rest are bad and the impact of sub-health state, produce small pox, Mottle, dark and gloomy and affect attractive in appearance, therefore facial skin needs to be maintained.Existing skin care item great majority are to join with chemical raw material System, it is not only not reaching to cosmetic result, brings injury to skin on the contrary.
Summary of the invention
In view of this, the present invention provides a kind of propolis ointment and preparation method thereof, it is possible to solve existing skin care item cosmetic result Difference, the technical problem that skin is damaged.
The technical scheme is that and be achieved in that:
A kind of propolis ointment, including the raw material of following parts by weight:
Preferably, described aliphatic alcohols material includes polyvinyl alcohol and glycerol.
Preferably, described polyvinyl alcohol is (30~50) with the mass ratio of described glycerol: (8~15).
Preferably, described plant extract includes Herba speranskiae tuberculatae extract, Europe HUOXUEDAN extract, Folium Menthae extract, Radix Sophorae Flavescentis Extract and Hamamelis virginiana extract.
Preferably, described Herba speranskiae tuberculatae extract, described Europe HUOXUEDAN extract, described Folium Menthae extract, described Radix Sophorae Flavescentis carry The mass ratio taking thing and described Hamamelis virginiana extract is (2~4): (2~4): (2~3): (2~3): (1.5~2).
Preferably, described vegetable oil includes oil of grapefruit and Jojoba seed oil.
Preferably, the parts by weight of described oil of grapefruit be with described Jojoba seed oil mass ratio be (1~3): (2~ 4)。
Preferably, described vitamin includes bad hematic acid and nicotinic acid.
Preferably, the mass ratio of described bad hematic acid and described nicotinic acid is 1:(1~2).
Present invention also offers the preparation method of above-mentioned propolis ointment, comprise the following steps:
Aliphatic alcohols material, methyl hydroxybenzoate, water are warming up under agitation 80~100 DEG C, stir 20~40min, Obtain the first solution;
After described first solution is cooled to 55~65 DEG C under agitation, add vegetable oil and trehalose, stirring After Jun Yun, obtain the second solution;
After described second solution is cooled to 30~50 DEG C, add propolis extract, Mel extract, plant extract, Vitamin and DMDM Hydantoin, after stirring, stand 15~24h, obtain propolis ointment.The invention have the benefit that
The propolis ointment that the present invention provides, by using propolis extract, Mel extract, aliphatic alcohols material, plant to carry Take thing, propolis ointment that vegetable oil, vitamin, trehalose, methyl hydroxybenzoate, DMDM Hydantoin prepare has typical liquid crystal Shape structure is as carrier, it is easy to infiltration, effective ingredient continuous action 24 hours, and effect is lasting, and effect is obvious.Further, the present invention Propolis ointment skin will not be damaged, can be used for hand and body skin and arthralgia surface, be possible not only to slow down Effect of pain and also whitening Antiageing effect, and by percutaneous technique to lumbago, take on neck, the gonalgia plays well Alleviate and therapeutical effect.
Detailed description of the invention
The invention discloses a kind of propolis ointment and preparation method thereof, those skilled in the art can use for reference present disclosure, suitable Realize when improving technological parameter.Special needs to be pointed out is, described similar replacement and change are for a person skilled in the art Being apparent from, they are considered as being included in the present invention.The method of the present invention and quote to be entered by preferred embodiment Having gone description, related personnel substantially can be to method described herein and application in without departing from present invention, spirit and scope It is modified or suitably changes and combine, realize and apply the technology of the present invention.
The invention provides a kind of propolis ointment, including the raw material of following parts by weight:
Propolis extract can nutrition skin care, and have the merits such as the strongest sterilization, anti-inflammatory anti-itch, anti-freezing anti-cracking, infection Can, but also cellular functional activity can be promoted, make cell regeneration.In the present invention, the parts by weight of propolis extract are 3 ~8 parts;In an embodiment of the present invention, the parts by weight of propolis extract are 4~6 parts.
Mel extract is possible to prevent skin allergy, is dried.In the present invention, the parts by weight of Mel extract are 1~5 Part;In an embodiment of the present invention, the parts by weight of Mel extract are 2~3 parts.
Plant extract plays moisturizing, moisturizing, crease-resistant effect.In an embodiment of the present invention, plant extract includes Herba speranskiae tuberculatae extract, Europe HUOXUEDAN extract, Folium Menthae extract, Radix Sophorae Flavescentis extract and Hamamelis virginiana extract;In the present invention Embodiment in, Herba speranskiae tuberculatae extract, Europe HUOXUEDAN extract, Folium Menthae extract, Radix Sophorae Flavescentis extract and Hamamelis virginiana are extracted The mass ratio of thing is (2~4): (2~4): (2~3): (2~3): (1.5~2).
In the present invention, the parts by weight of plant extract are 5~15 parts;In an embodiment of the present invention, plant extract The parts by weight of thing are 8~12 parts.
Aliphatic alcohols material plays moisture-keeping function.In an embodiment of the present invention, aliphatic alcohols material includes polyvinyl alcohol And glycerol.In other embodiments of the invention, polyvinyl alcohol is (30~50) with the mass ratio of glycerol: (8~15).
In the present invention, the parts by weight of aliphatic alcohols material are 30~45 parts;In other embodiments of the invention, fat The parts by weight of fat alcohols material are 35~40 parts.
Vegetable oil, for strengthening the flexibility of skin, plays lubrication.In an embodiment of the present invention, vegetable oil includes Oil of grapefruit and Jojoba seed oil;In other embodiments of the invention, oil of grapefruit is (1 with the mass ratio of Jojoba seed oil ~3): (2~4).
In the present invention, the parts by weight of vegetable oil are 3~8 parts;In an embodiment of the present invention, the weight portion of vegetable oil Number is 4~6 parts.
Vitamin is for improving the osmosis of propolis ointment, it is simple to skin absorption.In the present invention, the weight portion of vitamin Number is 0.4~1 part;In an embodiment of the present invention, the parts by weight of vitamin are 0.5~0.7 part.
In an embodiment of the present invention, microorganism includes ascorbic acid and nicotinic acid;In other embodiments of the present invention, bad blood The mass ratio of acid and nicotinic acid is 1:(1~2)
Trehalose can improve the defying age performance of skin.In the present invention, the parts by weight of trehalose are 0.5~3 part; In an embodiment of the present invention, the parts by weight of trehalose are 0.8~1.5 part.
Methyl hydroxybenzoate is used for suppressing bacteria breed in propolis ointment.In the present invention, the parts by weight of methyl hydroxybenzoate are 0.05 ~0.2 part;In an embodiment of the present invention, the parts by weight of methyl hydroxybenzoate are 0.08~0.15 part.
DMDM Hydantoin can improve the anti-microbial property of propolis ointment.In the present invention, the weight portion of DMDM Hydantoin Number is 0.1~0.5 part;In an embodiment of the present invention, the parts by weight of DMDM Hydantoin are 0.2~0.4 part.
In the present invention, the parts by weight of water are 30~50 parts;In an embodiment of the present invention, the parts by weight of water are 35 ~45 parts.
The propolis ointment that the present invention provides, by using propolis extract, Mel extract, aliphatic alcohols material, plant to carry Take thing, propolis ointment that vegetable oil, vitamin, trehalose, methyl hydroxybenzoate, DMDM Hydantoin prepare has typical liquid crystal Shape structure is as carrier, it is easy to infiltration, effective ingredient continuous action 24 hours, and effect is lasting, and effect is obvious.
Present invention also offers the preparation method of a kind of propolis ointment, comprise the following steps:
Stirring condition to aliphatic alcohols material, methyl hydroxybenzoate raw material in add cold water, and be warming up to 80~100 DEG C, stir 20~40min, obtain the first solution;The temperature of water is 10~30 DEG C;
After first solution is cooled to 55~65 DEG C under agitation, adds vegetable oil and trehalose, stir After, obtain the second solution;
After second solution is cooled to 30~50 DEG C, add propolis extract, Mel extract, plant extract, dimension life Element and DMDM Hydantoin, after stirring, stand 15~24h, obtain propolis ointment.
Wherein, propolis extract, Mel extract, aliphatic alcohols material, plant extract, vegetable oil, vitamin, Sargassum Sugar, methyl hydroxybenzoate, DMDM Hydantoin and water are the most same as above, do not repeat them here.
It should be noted that during obtaining the first solution, need to be stirred, in order to avoid causing material dissolution always Problem that is uneven, that generate precipitation.
The preparation method of the propolis ointment that the present invention provides, using natural non-stimulated material as the raw material of skin care item, preparation Propolis ointment skin will not be damaged, can be used for face, hand and body skin surface, be possible not only to improve whitening and Wrinkle removal effect, and greatly reduce the zest to skin.
In order to further illustrate the present invention, below in conjunction with embodiment, propolis ointment that the present invention provides and preparation method thereof is entered Row describes in detail.
Embodiment 1
Stirring condition to 23.7g polyvinyl alcohol, 6.32g glycerol, 0.08g methyl hydroxybenzoate raw material in add temperature be The 3g water of 10 DEG C, and it is warming up to 80 DEG C, stir 20min, obtain the first solution;
After first solution is cooled to 55 DEG C under agitation, add 3g oil of grapefruit, 4g Jojoba seed oil and 0.8g trehalose, after stirring, obtains the second solution;
After second solution is cooled to 30 DEG C, add 3g propolis extract, 1g Mel extract, the extraction of 0.87g Herba speranskiae tuberculatae Thing, 1.74g Europe HUOXUEDAN extract, 0.87g Folium Menthae extract, 0.87g Radix Sophorae Flavescentis extract, 0.65 Hamamelis virginiana extract, 0.24g ascorbic acid, 0.2g nicotinic acid and 0.2gDMDM hydantoin, after stirring, stand 15h, obtain propolis ointment.
Embodiment 2
Stirring condition to 34.6g polyvinyl alcohol, 10.4g glycerol, 0.2g methyl hydroxybenzoate raw material in add temperature be The 50g water of 20 DEG C, and it is warming up to 100 DEG C, stir 40min, obtain the first solution;
After first solution is cooled to 65 DEG C under agitation, add 2.4g oil of grapefruit, 1.6g Jojoba seed oil With 0.5g trehalose, after stirring, obtain the second solution;
After second solution is cooled to 50 DEG C, add 8g propolis extract, 5g Mel extract, the extraction of 3.68g Herba speranskiae tuberculatae Thing, 1.85g Europe HUOXUEDAN extract, 2.77g Folium Menthae extract, 1.85g Radix Sophorae Flavescentis extract, 1.85g Hamamelis virginiana extract, 0.2g ascorbic acid, 0.3g nicotinic acid and 0.4gDMDM hydantoin, after stirring, stand 18h, obtain propolis ointment.
Embodiment 3
Stirring condition to 26.9g polyvinyl alcohol, 8.1g glycerol, 0.05g methyl hydroxybenzoate raw material in add temperature be The 45g water of 30 DEG C, and it is warming up to 90 DEG C, stir 30min, obtain the first solution;
After first solution is cooled to 60 DEG C under agitation, add 1.6g oil of grapefruit, 6.4g Jojoba seed oil With 3g trehalose, after stirring, obtain the second solution;
After second solution is cooled to 40 DEG C, add 4g propolis extract, 3g Mel extract, the extraction of 3.51g Herba speranskiae tuberculatae Thing, 3.52g Europe HUOXUEDAN extract, 2.34g Folium Menthae extract, 3.52g Radix Sophorae Flavescentis extract, 2.11 Hamamelis virginiana extracts, 0.25g ascorbic acid, 0.45g nicotinic acid and 0.1gDMDM hydantoin, after stirring, stand 18h, obtain propolis ointment.
Embodiment 4
Stirring condition to 29.1 polyvinyl alcohol, 10.9g glycerol, 0.15g methyl hydroxybenzoate raw material in add temperature be The 35g water of 20 DEG C, and it is warming up to 90 DEG C, stir 303min, obtain the first solution;
After first solution is cooled to 60 DEG C under agitation, add 1g oil of grapefruit, 2g Jojoba seed oil and 1.5g trehalose, after stirring, obtains the second solution;
After second solution is cooled to 40 DEG C, add 6g propolis extract, 2g Mel extract, the extraction of 2.22g Herba speranskiae tuberculatae Thing, 2.22g Europe HUOXUEDAN extract, 1.11 Folium Menthae extracts, 1.11g Radix Sophorae Flavescentis extract, 1.34g Hamamelis virginiana extract, 0.33g ascorbic acid, 0.67g nicotinic acid and 0.5gDMDM hydantoin, after stirring, stand 24h, obtain propolis ointment.
Embodiment 5
Stirring condition to polyvinyl alcohol, glycerol, 0.1g methyl hydroxybenzoate raw material in add temperature be the 41g of 20 DEG C Water, and it is warming up to 90 DEG C, stir 30min, obtain the first solution;
After first solution is cooled to 60 DEG C under agitation, add 1.5g oil of grapefruit, 3g Jojoba seed oil and 1g trehalose, after stirring, obtains the second solution;
After second solution is cooled to 40 DEG C, add 5g propolis extract, 2.5g Mel extract, the extraction of 2.5g Herba speranskiae tuberculatae Thing, 2.5g Europe HUOXUEDAN extract, 2g Folium Menthae extract, 2g Radix Sophorae Flavescentis extract, 10.5g Hamamelis virginiana extract, 0.3g are anti- Bad hematic acid, 0.3g nicotinic acid and 0.3g DMDM Hydantoin, after stirring, stand 18h, obtain propolis ointment.
The propolis ointment preparing embodiment 1~5 carries out measure of merit, and each embodiment product selects 50 25~35 Year, the good volunteer of both hands health status more black, coarse, wrinkly carried out measure of merit.Experimenter's left hand uses common Skin care item, the right hand uses the propolis ointment of embodiment 1~5 preparation.The most each once period need not repaste uses other skin care item, hard Hold use 3 months, and every day, hand skin situation observed in record, the results are shown in Table 1.
Table 1 is the propolis ointment effect assessment data that the embodiment of the present invention 1~5 prepares
It addition, the cosmetic result of the aspects such as the whitening of experimenter's left hand, moisturizing, wrinkle apparently without the right hand effect want Good.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all essences in the present invention Within god and principle, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.

Claims (10)

1. a propolis ointment, it is characterised in that include the raw material of following parts by weight:
2. propolis ointment as claimed in claim 1, it is characterised in that described aliphatic alcohols material includes polyvinyl alcohol and glycerol.
3. propolis ointment as claimed in claim 2, it is characterised in that described polyvinyl alcohol is (30 with the mass ratio of described glycerol ~50): (8~15).
4. propolis ointment as claimed in claim 1, it is characterised in that described plant extract includes living in Herba speranskiae tuberculatae extract, Europe XUEDAN extract, Folium Menthae extract, Radix Sophorae Flavescentis extract and Hamamelis virginiana extract.
5. propolis ointment as claimed in claim 4, it is characterised in that described Herba speranskiae tuberculatae extract, described Europe HUOXUEDAN extract, Described Folium Menthae extract, described Radix Sophorae Flavescentis extract are (2~4) with the mass ratio of described Hamamelis virginiana extract: (2~4): (2 ~3): (2~3): (1.5~2).
6. propolis ointment as claimed in claim 1, it is characterised in that described vegetable oil includes oil of grapefruit and Jojoba seed oil.
7. propolis ointment as claimed in claim 6, it is characterised in that the parts by weight of described oil of grapefruit are and described Jojoba The mass ratio of seed oil is (1~3): (2~4).
8. propolis ointment as claimed in claim 1, it is characterised in that described vitamin includes bad hematic acid and nicotinic acid.
9. propolis ointment as claimed in claim 8, it is characterised in that the mass ratio of described bad hematic acid and described nicotinic acid be 1:(1~ 2)。
10. the preparation method of a propolis ointment as claimed in claim 1, it is characterised in that comprise the following steps:
Aliphatic alcohols material, methyl hydroxybenzoate, water are warming up under agitation 80~100 DEG C, stir 20~40min, obtain First solution;
After described first solution is cooled to 55~65 DEG C under agitation, adds vegetable oil and trehalose, stir After, obtain the second solution;
After described second solution is cooled to 30~50 DEG C, add propolis extract, Mel extract, plant extract, dimension life Element and DMDM Hydantoin, after stirring, stand 15~24h, obtain propolis ointment.
CN201610665542.XA 2016-08-12 2016-08-12 Propolis ointment and preparation method thereof Pending CN106074198A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106860118A (en) * 2017-03-25 2017-06-20 广州市聚吉科绿色化学共性技术研究院有限公司 A kind of anti-aging face cream

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103251531A (en) * 2013-04-28 2013-08-21 福建省梦娇兰日用化学品有限公司 Relief propolis cream

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103251531A (en) * 2013-04-28 2013-08-21 福建省梦娇兰日用化学品有限公司 Relief propolis cream

Non-Patent Citations (1)

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Title
山东谜季生物科技有限公司: "《http://125.35.6.80:8080/ftba/itownet/hzp_ba/fw/pz.jsp?processid=20160722152257n8btk&nid=20160722152257n8btk》", 15 July 2016 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106860118A (en) * 2017-03-25 2017-06-20 广州市聚吉科绿色化学共性技术研究院有限公司 A kind of anti-aging face cream

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