CN107407791B - 用于光学仪器的连续异步自动聚焦的系统和方法 - Google Patents
用于光学仪器的连续异步自动聚焦的系统和方法 Download PDFInfo
- Publication number
- CN107407791B CN107407791B CN201680020008.1A CN201680020008A CN107407791B CN 107407791 B CN107407791 B CN 107407791B CN 201680020008 A CN201680020008 A CN 201680020008A CN 107407791 B CN107407791 B CN 107407791B
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- China
- Prior art keywords
- autofocus
- optical
- light
- subsystem
- optical instrument
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/241—Devices for focusing
- G02B21/245—Devices for focusing using auxiliary sources, detectors
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/02—Objectives
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/06—Means for illuminating specimens
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
- G02B27/10—Beam splitting or combining systems
- G02B27/106—Beam splitting or combining systems for splitting or combining a plurality of identical beams or images, e.g. image replication
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
- G02B27/10—Beam splitting or combining systems
- G02B27/14—Beam splitting or combining systems operating by reflection only
- G02B27/145—Beam splitting or combining systems operating by reflection only having sequential partially reflecting surfaces
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
- G02B27/10—Beam splitting or combining systems
- G02B27/14—Beam splitting or combining systems operating by reflection only
- G02B27/148—Beam splitting or combining systems operating by reflection only including stacked surfaces having at least one double-pass partially reflecting surface
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
- G02B7/28—Systems for automatic generation of focusing signals
- G02B7/36—Systems for automatic generation of focusing signals using image sharpness techniques, e.g. image processing techniques for generating autofocus signals
- G02B7/38—Systems for automatic generation of focusing signals using image sharpness techniques, e.g. image processing techniques for generating autofocus signals measured at different points on the optical axis, e.g. focussing on two or more planes and comparing image data
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- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Microscoopes, Condenser (AREA)
- Automatic Focus Adjustment (AREA)
- Focusing (AREA)
Abstract
Description
Claims (20)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/675,199 US9921399B2 (en) | 2015-03-31 | 2015-03-31 | System and method for continuous, asynchronous autofocus of optical instruments |
US14/675199 | 2015-03-31 | ||
PCT/US2016/021329 WO2016160285A1 (en) | 2015-03-31 | 2016-03-08 | System and method for continuous, asynchronous autofocus of optical instruments |
Publications (2)
Publication Number | Publication Date |
---|---|
CN107407791A CN107407791A (zh) | 2017-11-28 |
CN107407791B true CN107407791B (zh) | 2020-04-14 |
Family
ID=57006268
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201680020008.1A Active CN107407791B (zh) | 2015-03-31 | 2016-03-08 | 用于光学仪器的连续异步自动聚焦的系统和方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US9921399B2 (zh) |
EP (1) | EP3278164A4 (zh) |
JP (1) | JP6662529B2 (zh) |
CN (1) | CN107407791B (zh) |
WO (1) | WO2016160285A1 (zh) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3287829A1 (en) * | 2016-08-25 | 2018-02-28 | Deutsches Krebsforschungszentrum | Method of and microscope with installation for focus stabilization |
CN107831142B (zh) * | 2017-12-07 | 2024-01-02 | 黄保坤 | 光散射共焦激发收集系统 |
JP6929549B2 (ja) * | 2018-02-14 | 2021-09-01 | 株式会社ピーエムティー | 露光装置及び露光方法 |
CN108375826B (zh) * | 2018-03-16 | 2021-01-29 | 昆山国显光电有限公司 | 显微镜及显微镜观测方法 |
JP7306810B2 (ja) * | 2018-09-28 | 2023-07-11 | シスメックス株式会社 | 顕微鏡システムの制御方法、顕微鏡システム、プログラム、記録媒体 |
WO2021184169A1 (zh) * | 2020-03-16 | 2021-09-23 | 中国科学院深圳先进技术研究院 | 一种用于显微镜的实时自动对焦系统 |
CN112799263A (zh) * | 2020-12-31 | 2021-05-14 | 苏州科韵激光科技有限公司 | 一种基于激光的物镜对焦方法及系统 |
EP4141870A1 (en) * | 2021-08-31 | 2023-03-01 | Microsoft Technology Licensing, LLC | Read head and methods for reading multilayer optical data storage media |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5767904A (en) * | 1980-10-16 | 1982-04-24 | Canon Inc | Deciding system for adjusting state of focus |
EP0379363B1 (en) | 1989-01-20 | 1994-12-28 | Matsushita Electric Industrial Co., Ltd. | Optical head device for use in optical disk system |
JP2591302B2 (ja) | 1990-09-26 | 1997-03-19 | 松下電器産業株式会社 | フォーカスエラー検出装置 |
JP3159746B2 (ja) | 1991-01-11 | 2001-04-23 | 旭光学工業株式会社 | 光磁気ディスク装置の信号検出系 |
JPH09230250A (ja) * | 1996-02-26 | 1997-09-05 | Hitachi Denshi Ltd | 光学顕微鏡自動合焦点装置 |
JP4384288B2 (ja) * | 1999-05-27 | 2009-12-16 | オリンパス株式会社 | 焦点検出装置 |
US6471388B1 (en) | 1999-12-30 | 2002-10-29 | Bji Energy Solutions Llc | Illumination apparatus for edge lit signs and display |
DE10024685A1 (de) * | 2000-05-18 | 2001-11-22 | Zeiss Carl Jena Gmbh | Anordnung zur konfokalen Autofokussierung |
JP4370554B2 (ja) | 2002-06-14 | 2009-11-25 | 株式会社ニコン | オートフォーカス装置およびオートフォーカス付き顕微鏡 |
US7813579B2 (en) * | 2004-05-24 | 2010-10-12 | Hamamatsu Photonics K.K. | Microscope system |
US7297910B2 (en) | 2005-12-30 | 2007-11-20 | General Electric Company | System and method for utilizing an autofocus feature in an automated microscope |
TWI439641B (zh) | 2007-05-20 | 2014-06-01 | 3M Innovative Properties Co | 用於側面發光型背光之準直光注入器 |
JP2009109792A (ja) | 2007-10-31 | 2009-05-21 | Fujifilm Corp | オートフォーカス装置及びこれを用いるカメラ |
JP5189966B2 (ja) * | 2008-11-28 | 2013-04-24 | 株式会社ミツトヨ | オートフォーカス装置 |
WO2010067256A1 (en) * | 2008-12-09 | 2010-06-17 | Koninklijke Philips Electronics N.V. | Autofocus for a microscope system. |
WO2010135323A1 (en) * | 2009-05-19 | 2010-11-25 | Bionanomatrix, Inc. | Devices and methods for dynamic determination of sample spatial orientation and dynamic repositioning |
US8362409B2 (en) | 2009-10-29 | 2013-01-29 | Applied Precision, Inc. | System and method for continuous, asynchronous autofocus of optical instruments |
US8558154B2 (en) * | 2009-10-29 | 2013-10-15 | Applied Precision, Inc. | System and method for continuous, asynchronous autofocus of optical instruments using multiple calibration curves |
JP5718662B2 (ja) * | 2011-01-31 | 2015-05-13 | 株式会社ミツトヨ | オートフォーカス装置 |
US20130013429A1 (en) | 2011-07-07 | 2013-01-10 | Daniel Allan Mooney | Systems, methods, and media for providing advertisements based upon relational data |
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2015
- 2015-03-31 US US14/675,199 patent/US9921399B2/en active Active
-
2016
- 2016-03-08 JP JP2017550922A patent/JP6662529B2/ja active Active
- 2016-03-08 CN CN201680020008.1A patent/CN107407791B/zh active Active
- 2016-03-08 WO PCT/US2016/021329 patent/WO2016160285A1/en active Application Filing
- 2016-03-08 EP EP16773702.2A patent/EP3278164A4/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP6662529B2 (ja) | 2020-03-11 |
US9921399B2 (en) | 2018-03-20 |
EP3278164A4 (en) | 2018-12-12 |
WO2016160285A1 (en) | 2016-10-06 |
CN107407791A (zh) | 2017-11-28 |
EP3278164A1 (en) | 2018-02-07 |
US20160291307A1 (en) | 2016-10-06 |
JP2018516380A (ja) | 2018-06-21 |
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Effective date of registration: 20210824 Address after: Massachusetts, USA Patentee after: Globegroup life technology consulting America Co.,Ltd. Address before: New York State, USA Patentee before: General Electric Co. |
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20220104 Address after: Germany Wetzlar Patentee after: LEICA MICROSYSTEMS CMS GmbH Address before: Massachusetts Patentee before: Globegroup life technology consulting America Co.,Ltd. |