CN107397775A - A kind of panax japonicus extract solution and its extracting method and panax japonicus drink and preparation method thereof - Google Patents
A kind of panax japonicus extract solution and its extracting method and panax japonicus drink and preparation method thereof Download PDFInfo
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- CN107397775A CN107397775A CN201710665405.0A CN201710665405A CN107397775A CN 107397775 A CN107397775 A CN 107397775A CN 201710665405 A CN201710665405 A CN 201710665405A CN 107397775 A CN107397775 A CN 107397775A
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- panax japonicus
- drink
- coarse powder
- panax
- extract solution
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- MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 description 1
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- QFJUYMMIBFBOJY-UXZRXANASA-N Panaxatriol Chemical compound C[C@]1([C@H]2CC[C@@]3([C@@H]2[C@H](O)C[C@H]2[C@]3(C[C@@H](O)[C@H]3C(C)(C)[C@@H](O)CC[C@@]32C)C)C)CCCC(C)(C)O1 QFJUYMMIBFBOJY-UXZRXANASA-N 0.000 description 1
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- PALNVYHUKHRDOP-UHFFFAOYSA-N UNPD162310 Natural products COC(=O)C1(C)CCC2(CCC3(C)C(=CCC4C5(C)CCC(OC6OC(CO)C(O)C(OC7OC(CO)C(O)C(O)C7O)C6O)C(C)(C)C5CCC34C)C2C1)C(=O)O PALNVYHUKHRDOP-UHFFFAOYSA-N 0.000 description 1
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- HZLWUYJLOIAQFC-UHFFFAOYSA-N prosapogenin PS-A Natural products C12CC(C)(C)CCC2(C(O)=O)CCC(C2(CCC3C4(C)C)C)(C)C1=CCC2C3(C)CCC4OC1OCC(O)C(O)C1O HZLWUYJLOIAQFC-UHFFFAOYSA-N 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- TXUSTSJRABHHQP-UFGIQYKASA-N pulsatilla saponin D Natural products C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](CO[C@H]2O[C@H]3CC[C@@]4(C)[C@@H](CC[C@]5(C)[C@@H]4CC=C6[C@@H]7CC(C)(C)CC[C@@]7(CC[C@@]56C)C(=O)O)[C@]3(C)O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H](O)[C@H](O)[C@H]1O TXUSTSJRABHHQP-UFGIQYKASA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Non-Alcoholic Beverages (AREA)
Abstract
The present invention relates to field of traditional Chinese medicine extraction, in particular to a kind of panax japonicus extract solution and its extracting method and panax japonicus drink and preparation method thereof.A kind of extracting method of panax japonicus, comprises the following steps：Panax japonicus is crushed, obtains panax japonicus coarse powder；Panax japonicus coarse powder adds 55 70 ° of grain wine, 54 144h of closed placement after mixing；Then diacolation is carried out, collects percolate；Panax japonicus coarse powder is squeezed, obtains pressed liquor；Percolate merges with pressed liquor, removes alcohol, obtains panax japonicus extract solution.The present inventor extracts the active component of panax japonicus using the grain wine of certain number of degrees, extraction efficiency is high, and the extract solution function admirable that extraction obtains, and overcomes the phenomenon that water-solubility impurity is too many during water extracts, the energy is saved, so as to ensure product efficacy, quality and mouthfeel.
Description
Technical field
The present invention relates to field of traditional Chinese medicine extraction, in particular to a kind of panax japonicus extract solution and its extracting method and
Panax japonicus drink and preparation method thereof.
Background technology
With stepping up for living standards of the people, the consciousness of taking care of health of people is more and more strong, to the demand of health beverages
It is more and more big, it is more and more high to the quality requirement of health beverages, the health-care efficacy of health beverages is required definitely, through preliminary
Statistics, at present in 180 plurality kinds of health care drinks of the whole nation, have dissipate stasis of blood hemostasis, swelling and pain relieving, expelling phlegm and arresting coughing, qi-restoratives strong without a kind of
Strong and other effects health beverages.
Existing various oral liquids, syrup etc. are without analgesia, function of polysaccharide, also, existing various antalgesics, hypoglycemic
Most of medicine is chemical substance, there is larger side effect.
In view of this, it is special to propose the present invention.
The content of the invention
The first object of the present invention is to provide a kind of extracting method of panax japonicus, and this method uses the grain of certain alcoholic strength
Food wine dipper takes the effective active composition of panax japonicus, by progressively handling, the effective active composition recovery rate in obtained extract solution
Reach more than 75%.
The second object of the present invention is the panax japonicus extract solution that the extracting method for providing above-mentioned panax japonicus obtains, and this is carried
The active component integrated in liquid in panax japonicus and grain wine in addition to ethanol is taken, analgesia, hypoglycemic and other effects are good after cooperation.
The third object of the present invention is to provide a kind of panax japonicus drink, is extracted by above-mentioned panax japonicus and mixed with auxiliary material and water
Conjunction forms, and is easy to eat, and mouthfeel is good, and having filled up health beverages, to possess dissipate stasis of blood hemostasis, swelling and pain relieving, expelling phlegm and arresting coughing, qi-restoratives strong
The blank of strong health-care efficacy.
The fourth object of the present invention is the preparation method for providing described panax japonicus drink, and this method is easily operated, has
Beneficial to large-scale production, obtained panax japonicus drink mouthfeel is good.
In order to realize the above-mentioned purpose of the present invention, spy uses following technical scheme：
A kind of extracting method of panax japonicus, comprises the following steps：
Panax japonicus is crushed, obtains panax japonicus coarse powder；
The panax japonicus coarse powder adds 55-70 ° of grain wine, closed placement 54-144h after mixing；
Then diacolation is carried out, collects percolate；
Panax japonicus coarse powder is squeezed, obtains pressed liquor；
The percolate merges with the pressed liquor, removes alcohol, obtains panax japonicus extract solution.
Panax japonicus is a kind of rare rare traditional Chinese medicine, has the effect of Xu-tonic, cough-relieving apophlegmatic, hemostasis and pain-relieving.It is main
It is weak after curing the disease, poor appetite, consumptive disease phlegm cough, spit blood, spitting blood, bleeding from five sense organs or subcutaneous tissue, have blood in stool, hematuria, vicarious menstruation, uterine bleeding, traumatism and bleeding, miasma
Lump in the abdomen, Huang blood Amenorrhea, postpartum stasis stomachache, rheumatic arthritis, instep beat the symptoms such as damage, carbuncle swells, hemorrhoid, venomous snake bite.
The principle active component of panax japonicus is oleanolic acid, panoxadiol, panaxatriol, saponin(e etc., and wherein saponin(e includes
Ginsenoside Re, panax japonicus saponin IV, panax japonicus saponin IVa, panax japonicus saponin V, panax japonicus saponin -2 etc..
Modern medicine proves that panax japonicus has following pharmacological action：
(1) antiinflammatory action.Panax japonicus decoction 10g (crude drug)/kg gavages, causes to rat egg white, formaldehyde or dextran
Arthritis, have obvious inhibitory action.
(2) delaying senility function.During 323 μ g/ml of panax japonicus total saponins, normal induced lung is hooked and starches spontaneous lipid peroxide
Raw relative has inhibitory action, can suppress the generation of the lung microsome lipid peroxide of Fez+ sides cystine induction.There is stronger removing
Superoxide anion radical effect coffee.Panax japonicus total saponins 0.824% (content is 8% in crude drug), mouse skin hydroxyproline
Content increase.Panax japonicus polysaccharides can activate reticuloendothelial system.
(3) hypoglycemic effect.Olive methane series saponin(e contained by panax japonicus, there is stronger hypoglycemic effect.
(4) to the protective effect of chemical damage.Panax japonicus is to CCl4Induce a large amount of hepatic injuries cause in serum GPT and
Rise horizontal MDA has obvious inhibitory action, and pathology of livers also substantially mitigates.
Nevertheless, it yet there are no the method for relatively effective extraction panax japonicus.The present inventor studies discovery repeatedly, no
The effect extracted with the grain wine of the number of degrees is different, if the number of degrees of grain wine are low, such as 40 °, then extraction effect is bad, and recovery rate exists
Less than 45%, and if the number of degrees of grain wine are too high, such as 80 °, extraction effect is still bad, and recovery rate is also below 45%.
For the present invention using the active component of the grain wine extraction panax japonicus of certain number of degrees, extraction efficiency is high, recovery rate more than 75%,
And the obtained extract solution function admirable of extraction, overcome during water extraction that water-solubility impurity is too many, extraction efficiency is not high lacks
Fall into, the energy is saved, so as to ensure product efficacy, quality and mouthfeel.
Panax japonicus coarse powder can be any fineness, find that the coarse powder of the coarse powder content between 24 mesh and 65 mesh is not through experiment
Less than 60%, and panax japonicus coarse powder more than 65 mesh be less than 40% when, extraction effect is preferable.Because if fine powder is too many,
Percolation effect is deteriorated.Preferably, coarse powder content of the particle diameter of the panax japonicus coarse powder between 24 mesh and 65 mesh is not less than 60%,
Also, panax japonicus coarse powder more than 65 mesh is less than 40%.
The number of degrees of grain wine can be 55 °, 58 °, 60 °, 65 °, 70 ° etc..Found through experiment, extraction effect is preferably
60-65 ° of grain wine.Preferably, the number of degrees of the grain wine are 60-65 °.Extracted, obtained using the grain wine of the number of degrees
Effective active composition extraction rate reached in extract solution is to more than 88%.
The main provenance of panax japonicus makes in Hubei Province's Enshitujianationalitymiaonationality Autonomous Prefecture, sample trial-production and the amplification of middle sample
With the panax japonicus for the autonomous prefecture that bestows favour, rich in trace elements of selenium.Material quality is superior, extract solution excellent performance, and selenium-rich increase
The effect of obtained extract solution.Preferably, the panax japonicus is organic selenium-rich panax japonicus.
The ratio of panax japonicus coarse powder and grain wine is appropriate, and grain wine can sufficiently soak panax japonicus coarse powder, and both fill
The interreaction divided so that not only effective active composition content is high for the liquid extracted, and effect is more superior.Preferably, institute
The part by weight for stating panax japonicus coarse powder and the grain wine is 1:6-20.Such as, in certain embodiments, panax japonicus coarse powder and grain
The part by weight of wine is 1:6、1:8、1:10、1:12、1:15、1:18、1:20 etc..
In order to reach more preferable extraction effect, and the effective active composition content in extract solution is appropriate, it is preferable that described
The part by weight of panax japonicus coarse powder and the grain wine is 1：10-15.
Preferably, the grain wine adds in two steps, the first step, and panax japonicus coarse powder is using part by weight as 1:1-3 adds grain
Eat wine, closed placement 6-48h after mixing；Second step, the grain wine of surplus is added, closed placement 48-96h after mixing.
By adding grain wine step by step, with sufficiently by the active ingredient dissolution in panax japonicus.
Panax japonicus coarse powder mixes with grain wine, can be placed in glass, pottery, rustless steel container.
In order to reach the purpose for more fully extracting effective active composition therein, it is preferable that extracted with 1kg panax japonicuses
Meter, collection percolate per minute are no more than 1ml.
It is preferably, described that to remove alcohol be the way of distillation or reclaiming by filtration ethanol.
The way of distillation reclaims ethanol：Panax japonicus extract solution is put in distiller, by the way that ethanol is recovered under reduced pressure or puts thin film evaporation
Ethanol is reclaimed in device, obtains panax japonicus stoste and ethanol.
Reclaiming by filtration ethanol：Panax japonicus extract solution is reclaimed by film normal temperature concentration systems and separated, obtains panax japonicus stoste
And ethanol.
Present invention also offers panax japonicus extract solution made from said extracted method.Effective work in the panax japonicus extract solution
Property component content it is high, based on the effective active composition in crude drug in whole, the content of active component is more than 75%.Wherein, effectively
Active component includes saponin, polysaccharide, amino acid etc..
Present invention also offers a kind of panax japonicus drink, mainly mixed with auxiliary material and water by above-mentioned panax japonicus extract solution and
Into.Water can be distilled water, pure water or purified water etc..
The addition of panax japonicus extract solution is adjusted according to the extracted amount of panax japonicus active ingredient with people's amount effective dose
It is whole.
By adding auxiliary material, obtained panax japonicus drink is easy to be accepted by the public.
Preferably, the auxiliary material includes sweet substance, and the sweet substance is honey, preferably pure ferine honey.Pass through
Add sweet substance, the taste of panax japonicus drink made from regulation.
Found through tasting, sweet substance is honey, particularly pure ferine honey, better tasting, and product color is also more preferably.
Further, the component of the panax japonicus drink is：The addition of panax japonicus extract solution presses the panax japonicus drink
Middle primary crude drug content is added for 5%-10%, and sweet substance 5%-8%, surplus is water.
The proportioning of each raw material is adjusted, obtained panax japonicus drink joins fragrance sweet tea.
Further, the drink includes oral liquid, beverage, syrup.
Present invention also offers the preparation method of above-mentioned panax japonicus drink, each component mixing by weight, through processing
Afterwards, sterilizing obtains panax japonicus drink.
Further, the processing is any of freezing, absorption method, Treatment with Ultrafiltration.
Freezing：Panax japonicus drink preparation liquid is put into refrigerating chamber to freeze more than 48 hours, through initial filter, refined filtration.
Absorption method：Appropriate adsorbent (such as activated carbon) is added to stir several minutes of filtrations panax japonicus drink preparation liquid, then through just
Filter, refined filtration.
Ultrafiltration：Panax japonicus drink is prepared into liquid pretreatment filtration, then through ultrafiltration.
Further, the sterilizing uses Co 60 gamma rays radiation sterilization.
For obtained panax japonicus drink through filling, gland, coding, packaging, inspection is qualified to obtain panax japonicus drink finished product.
Chinese medicine panax japonicus is that Araliaceae panax japonicus is《Pharmacopoeia of People's Republic of China》Version records kind within 2015, its
Root-like stock and meat root tuber, there is dissipate stasis of blood hemostasis, swelling and pain relieving, expelling phlegm and arresting coughing, Xu-tonic and other effects, by panax japonicus by tradition
Technique and modern science and technology technology organically combine the panax japonicus drink prepared, still possess the peculiar effect such as above-mentioned, and drink agent is sent out
More quickly and effectively more directly, and panax japonicus drink is single preparations of ephedrine, no incompatibility, product quality is guaranteed for the effect of waving.
Compared with prior art, beneficial effects of the present invention are：
(1) extracting method of a kind of panax japonicus provided by the invention, panax japonicus is extracted using the grain wine of certain alcoholic strength
Effective active composition, by progressively handling, effective active composition extraction rate reached in obtained extract solution to more than 75%.
(2) panax japonicus extract solution produced by the present invention, in the extract solution in comprehensive panax japonicus and grain wine in addition to ethanol
Active component, analgesia, hypoglycemic and other effects are good after cooperation.
(3) panax japonicus drink provided by the invention, is easy to eat, and mouthfeel is good, has filled up health beverages and possesses the scattered stasis of blood and has stopped
Blood, swelling and pain relieving, expelling phlegm and arresting coughing, Xu-tonic health-care efficacy blank.
(4) preparation method of panax japonicus drink provided by the invention, this method is easily operated, is beneficial to large-scale production,
Obtained panax japonicus drink mouthfeel is good.
Embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the present invention.It is unreceipted specific in embodiment
Condition person, the condition suggested according to normal condition or manufacturer are carried out.Agents useful for same or the unreceipted production firm person of instrument, it is
The conventional products that can be obtained by commercially available purchase.
Embodiment 1
A kind of extracting method of panax japonicus, comprises the following steps：
Selecting main provenance, the panax japonicus is rich in micro in the panax japonicus of Hubei Province's Enshitujianationalitymiaonationality Autonomous Prefecture
Elemental selenium；
Panax japonicus is crushed, first crosses 24 mesh sieves, then crosses 65 mesh sieves, also, the coarse powder content between 24 mesh and 65 mesh is not
Less than 60%, the fine powder for crossing 65 mesh sieves is less than 40%, obtains panax japonicus coarse powder；
Group 1：Panax japonicus coarse powder adds 40 ° of grain wine, and the part by weight of panax japonicus coarse powder and grain wine is 1:3, it is put into close
Close in container, closed placement 24h after mixing, then add the grain wine of surplus, closed placement 64h, the total addition level of grain wine
For 10 times of panax japonicus coarse powder weight；
Group 2：Panax japonicus coarse powder adds 55 ° of grain wine, and the part by weight of panax japonicus coarse powder and grain wine is 1:3, it is put into close
Close in container, closed placement 24h after mixing, then add the grain wine of surplus, closed placement 64h, the total addition level of grain wine
For 10 times of panax japonicus coarse powder weight；
Group 3：Panax japonicus coarse powder adds 60 ° of grain wine, and the part by weight of panax japonicus coarse powder and grain wine is 1:3, it is put into close
Close in container, closed placement 24h after mixing, then add the grain wine of surplus, closed placement 64h, the total addition level of grain wine
For 10 times of panax japonicus coarse powder weight；
Group 4：Panax japonicus coarse powder adds 65 ° of grain wine, and the part by weight of panax japonicus coarse powder and grain wine is 1:3, it is put into close
Close in container, closed placement 24h after mixing, then add the grain wine of surplus, closed placement 64h, the total addition level of grain wine
For 10 times of panax japonicus coarse powder weight；
Group 5：Panax japonicus coarse powder adds 70 ° of grain wine, and the part by weight of panax japonicus coarse powder and grain wine is 1:3, it is put into close
Close in container, closed placement 24h after mixing, then add the grain wine of surplus, closed placement 64h, the total addition level of grain wine
For 10 times of panax japonicus coarse powder weight；
Group 6：Panax japonicus coarse powder adds 80 ° of grain wine, and the part by weight of panax japonicus coarse powder and grain wine is 1:3, it is put into close
Close in container, closed placement 24h after mixing, then add the grain wine of surplus, closed placement 64h, the total addition level of grain wine
For 10 times of panax japonicus coarse powder weight；
It is then charged into single-stage or multistage diacolation bucket, slow diacolation, in terms of the extraction of 1kg panax japonicuses, collection diacolation per minute
Liquid is no more than 1ml, and collection obtains percolate；
Panax japonicus coarse powder is squeezed, obtains pressed liquor；
Percolate merges with pressed liquor, removes alcohol, obtains panax japonicus extract solution.
TLC determines panax japonicus and saponin, polysaccharide, amino acid in panax japonicus extract solution, calculates these three compositions
The extraction efficiency of progress, as a result as shown in table 1.
The extraction efficiency of table 1
| Group | Saponin | Polysaccharide | Amino acid |
| Group 1 | 40% | 34% | 42% |
| Group 2 | 77% | 75% | 78% |
| Group 3 | 89% | 90% | 90% |
| Group 4 | 90% | 91% | 90% |
| Group 5 | 78% | 80% | 81% |
| Group 6 | 30% | 32% | 30% |
It can be seen that it is notable to panax japonicus extraction effect using 55-70 ° of grain wine, wherein being extracted with 60-65 ° of grain wine
It is better.In addition, detection is found, the impurity content in extract is below 1%.
Embodiment 2
A kind of extracting method of panax japonicus, comprises the following steps：
Selecting main provenance, the panax japonicus is rich in micro in the panax japonicus of Hubei Province's Enshitujianationalitymiaonationality Autonomous Prefecture
Elemental selenium；
Panax japonicus is crushed, first crosses 24 mesh sieves, then crosses 65 mesh sieves, also, the coarse powder content between 24 mesh and 65 mesh is not
Less than 60%, the fine powder for crossing 65 mesh sieves is no more than 40%, obtains panax japonicus coarse powder；
Panax japonicus coarse powder adds 60 ° of grain wine, and the part by weight of panax japonicus coarse powder and grain wine is 1:1, it is put into closed appearance
In device, closed placement 48h after mixing, the grain wine of surplus is then added, closed placement 48h, the total addition level of grain wine is bamboo
6 times of section ginseng coarse powder weight；
It is then charged into single-stage or multistage diacolation bucket, slow diacolation, in terms of the extraction of 1kg panax japonicuses, collection diacolation per minute
Liquid is no more than 1ml, and collection obtains percolate；
Panax japonicus coarse powder is squeezed, obtains pressed liquor；
Percolate merges with pressed liquor, removes alcohol, obtains panax japonicus extract solution.
TLC determines panax japonicus and saponin, polysaccharide, amino acid in panax japonicus extract solution, and these three compositions are carried out
Extraction efficiency be respectively 88%, 89%, 90%, also, impurity content is below 1%.
Embodiment 3
A kind of extracting method of panax japonicus, comprises the following steps：
Selecting main provenance, the panax japonicus is rich in micro in the panax japonicus of Hubei Province's Enshitujianationalitymiaonationality Autonomous Prefecture
Elemental selenium；
Panax japonicus is crushed, first crosses 24 mesh sieves, then crosses 65 mesh sieves, also, the coarse powder content between 24 mesh and 65 mesh is not
Less than 60%, the fine powder for crossing 65 mesh sieves is no more than 40%, obtains panax japonicus coarse powder；
Panax japonicus coarse powder adds 65 ° of grain wine, and the part by weight of panax japonicus coarse powder and grain wine is 1:3, it is put into closed appearance
In device, closed placement 12h after mixing, the grain wine of surplus is then added, closed placement 96h, the total addition level of grain wine is bamboo
20 times of section ginseng coarse powder weight；
It is then charged into single-stage or multistage diacolation bucket, after impregnating 96h, slow diacolation, in terms of the extraction of 1kg panax japonicuses, every point
Clock collects percolate and is no more than 1ml, and collection obtains percolate；
Panax japonicus coarse powder is squeezed, obtains pressed liquor；
Percolate merges with pressed liquor, removes alcohol, obtains panax japonicus extract solution.
TLC determines panax japonicus and saponin, polysaccharide, amino acid in panax japonicus extract solution, and these three compositions are carried out
Extraction efficiency be respectively 88%, 89%, 90%, also, impurity content is below 1%.
Embodiment 4
The panax japonicus extract solution that embodiment is extracted for 1 group 3 is prepared into panax japonicus drink in the following proportions；
Group 1：Percentage, panax japonicus extract solution 81%, pure ferine honey 8%, surplus is water；
Group 2：Percentage, panax japonicus extract solution 63%, pure ferine honey 5%, surplus is water；
Group 3：Percentage, panax japonicus extract solution 72%, pure ferine honey 6%, surplus is water；
Group 4：Percentage, panax japonicus extract solution 75%, pure ferine honey 7%, surplus is water；
Control group 1：Percentage, panax japonicus extract solution 75%, white sugar 7%, surplus are water；
Control group 2：Percentage, panax japonicus extract solution 75%, surplus are water.
Group 1-4 and control group 1-2 each component are mixed, panax japonicus drink is obtained and prepares liquid, is placed in refrigerating chamber freezing 48
More than hour, through initial filter, refined filtration, sterilize, packing, obtain the product that every is 10ml.
To panax japonicus drink progress Taste evaluation (volunteer in 50 all ages and classes stages) made from group 1-4, while with
Panax japonicus extract solution as a control group, is given a mark after trial test, is averaged, and obtains score value to the end.As a result it is as shown in table 2.
The score value of table 2
Taste, obtained panax japonicus drink is adjusted by adding sweet taste auxiliary material in panax japonicus extract solution produced by the present invention
Product are easy to be accepted by the public, also, transparent using the micro- Huang of panax japonicus drink made from the cooperation of pure ferine honey, taste ginseng perfume side
Sweet tea, resultant effect are more excellent.
Experimental example 1
Panax japonicus drink made from group 4 is subjected to clinic and takes checking, is had the following effects that：
1. after drinking one, 30 minutes every time, various pain symptoms are relieved or disappeared.
2. drinking 2-3 times daily, after continuous 7 days, hyperglycemic patients blood-sugar content is substantially reduced, and dosage can be reduced,
Groups of people are until be discontinued.
Panax japonicus drink provided by the invention, is easy to eat, and mouthfeel is good, and analgesia, hypoglycemic and other effects are good, have filled up guarantor
Strong drink possess dissipate stasis of blood hemostasis, swelling and pain relieving, expelling phlegm and arresting coughing, Xu-tonic health-care efficacy blank.
Although illustrate and describing the present invention with specific embodiment, but will be appreciated that without departing substantially from the present invention's
Many other change and modification can be made in the case of spirit and scope.It is, therefore, intended that in the following claims
Including belonging to all such changes and modifications in the scope of the invention.
Claims (10)
1. a kind of extracting method of panax japonicus, it is characterised in that comprise the following steps：
Panax japonicus is crushed, obtains panax japonicus coarse powder；
The panax japonicus coarse powder adds 55-70 ° of grain wine, closed placement 54-144h after mixing；
Then diacolation is carried out, collects percolate；
Panax japonicus coarse powder is squeezed, obtains pressed liquor；
The percolate merges with the pressed liquor, removes alcohol, obtains panax japonicus extract solution.
2. extracting method according to claim 1, it is characterised in that the particle diameter of the panax japonicus coarse powder is in 24 mesh and 65 mesh
Between coarse powder content be not less than 60%, also, panax japonicus coarse powder more than 65 mesh be less than 40%；
Preferably, the number of degrees of the grain wine are 60-65 °；
Preferably, the panax japonicus is organic selenium-rich panax japonicus.
3. extracting method according to claim 1, it is characterised in that the weight of the panax japonicus coarse powder and the grain wine
Ratio is 1:6-20, preferably 1：10-15；
Preferably, the grain wine adds in two steps, the first step, and panax japonicus coarse powder is using part by weight as 1:1-3 adds grain wine,
Closed placement 6-48h after mixing；Second step, the grain wine of surplus is added, closed placement 48-96h after mixing；
Preferably, in terms of the extraction of 1kg panax japonicuses, collection percolate per minute is no more than 1ml；
It is preferably, described that to remove alcohol be the way of distillation or reclaiming by filtration ethanol.
4. panax japonicus extract solution made from the extracting method described in claim any one of 1-3.
5. a kind of panax japonicus drink, it is characterised in that mainly mixed as the panax japonicus extract solution described in claim 4 with auxiliary material and water
Conjunction forms.
6. panax japonicus drink according to claim 5, it is characterised in that the auxiliary material includes sweet substance, the sweet taste
Material is honey, preferably pure ferine honey.
7. panax japonicus drink according to claim 6, it is characterised in that the component of the panax japonicus drink is：Panax japonicus
It is 7%-9% additions that the addition of extract solution, which presses primary crude drug content in the panax japonicus drink, and sweet substance 5%-8% is remaining
Measure as water.
8. according to the panax japonicus drink described in claim any one of 5-7, it is characterised in that the drink includes oral liquid, drink
Material, syrup.
9. the preparation method of the panax japonicus drink described in claim any one of 5-8, it is characterised in that each component by weight
Mixing, after processing, sterilizing obtains panax japonicus drink.
10. the preparation method of panax japonicus drink according to claim 9, it is characterised in that the processing is freezing, inhaled
Any of attached method, Treatment with Ultrafiltration；
Preferably, the sterilizing uses Co 60 gamma rays radiation sterilization.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111297878A (en) * | 2020-01-06 | 2020-06-19 | 上海中医药大学 | Hypoglycemic active ingredient in panax japonicus, hypoglycemic composition and application thereof |
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