CN107375713A

CN107375713A - The Chinese medical extract and preparation method and external preparation of red blood silk effect are removed with Eradicates

Info

Publication number: CN107375713A
Application number: CN201710536667.7A
Authority: CN
Inventors: 万家林
Original assignee: Hefei Fengruilong Biological Technology Co Ltd
Current assignee: Hefei Fengruilong Biological Technology Co Ltd
Priority date: 2017-07-04
Filing date: 2017-07-04
Publication date: 2017-11-24

Abstract

The present invention discloses a kind of Chinese medical extract and preparation method and external preparation that red blood silk effect is removed with Eradicates, and the medicinal material that the Chinese medical extract is matched by following weight is made：15~25 parts of safflower, 15~25 parts of the bark of eucommia, 15~25 parts of the Radix Astragali, 20~30 parts of meadow pine, 2~8 parts of purple perilla, 30~40 parts of grape pip, 10~30 parts of the stem of noble dendrobium, 3~5 parts of chamomile, 3~8 parts of Radix picrorrhizae, 5~10 parts of ivy, 2~6 parts of rattletop.Skin care formulation is made up of described Chinese medical extract and skin care item auxiliary material, each medicinal material contains the active components of plants of uniqueness in Chinese medicine composition of the present invention, science is arranged in pairs or groups the ratio of each composition, synergy, the effect of red blood trace on face being removed with significant Eradicates, the Chinese medical extract is applied in external use skin care, can effectively solve the problems, such as red blood trace on face.

Description

The Chinese medical extract and preparation method and external preparation of red blood silk effect are removed with Eradicates

Technical field

The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medical extract and system that red blood silk effect is removed with Eradicates Preparation Method and external preparation.

Background technology

In recent years, the sensitive related dermal problem triggered of skin was increasingly becoming the heat of cosmetic industry and medical industries research Point.Wherein, the red blood silk that facial telangiectasias triggers not only has a strong impact on patient's beauty, and the psychology of patient is also resulted in greatly Burden.

Red blood trace on face, medically also known as facial telangiectasias, that is, the elasticity reduction of capillary wall are crisp Property enhancing, the uneven expansion of continuous vessel even ruptures, and causes skin of face general red, the blood capillary of the visible expansion of naked eyes Pipe, it is often accompanied by red or aubergine plaque-like, point-like, wire or starlike etc. phenomenon, referred to as telangiectasia.

It is more based on laser therapy physical method to cure the means of red blood silk both at home and abroad at present, is pyrolyzed by selective light former Reason, the hemoglobin acted in lesion vesselses, make lesion vesselses pyrolysis, absorb, disappear.But laser therapy has pain, hand It is preoperative to use antalgica, tranquillizer or anesthetic in advance.Treatment method is improper to be likely to occur oedema or leaves blackspot, and valency Lattice costly, it is less to be applicable crowd.At present, cosmetics for external use treatment is more based on skin of releiving, and only French a few families are medicinal Cosmetics company's (Avene, managing skin spring, L'Oreal) releases the cosmetics specifically for red blood silk, and its functional raw material is to repair hair Based on thin blood vessel, but specific aim is poor.

China has abundant Chinese herbal medicine resource and more perfect tcm theory system.Using tcm theory as guidance, profit Active ingredient of Chinese herbs is extracted with modern biotechnology, applied to various functions cosmetics, to promoting China's cosmetic industry with Medicine beauty industry is respectively provided with important realistic meaning.

The content of the invention

The present invention proposes a kind of Chinese medical extract and preparation method and external preparation that red blood silk effect is removed with Eradicates, and this is outer Arranged in pairs or groups with preparation with different plant components and repair damaged skin epidermis, repaired impaired capillary, red blood is dispelled from root Silk does not recur.

The technical proposal of the invention is realized in this way：

A kind of Chinese medical extract that red blood silk effect is removed with Eradicates, the medicinal material matched by following weight are made：Safflower 15 ~25 parts, 15~25 parts of the bark of eucommia, 15~25 parts of the Radix Astragali, 20~30 parts of meadow pine, 2~8 parts of purple perilla, 30~40 parts of grape pip, the stem of noble dendrobium 10~30 parts, 3~5 parts of chamomile, 3~8 parts of Radix picrorrhizae, 5~10 parts of ivy, 2~6 parts of rattletop.

Wherein it is preferred to a kind of Chinese medical extract that red blood silk effect is removed with Eradicates, is the medicinal material matched by following weight It is made：18~22 parts of safflower, 18~22 parts of the bark of eucommia, 18~22 parts of the Radix Astragali, 22~28 parts of meadow pine, 3~7 parts of purple perilla, grape pip 32 ~38 parts, 15~25 parts of the stem of noble dendrobium, 3~5 parts of chamomile, 4~6 parts of Radix picrorrhizae, 6~8 parts of ivy, 3~8 parts of rattletop.

A kind of preparation method with Chinese medical extracts of the Eradicates except red blood silk effect, comprises the following steps：

(1) each medicinal material is weighed by proportioning；

(2) bulk drug is put into water and decocts water extraction twice, for the first time the part by weight 1 of the medicinal material of extraction and water:10~ 1:20, decocting time is 60~180min, obtains extract solution, and first time is extracted into gained extract solution filters out, and filter residue adds relative The water that 8~15 times of filter residue weight is decocted, and decocting time is that 60~120min obtains second of extract solution, merges extract solution twice Obtain external application Chinese medicine extract crude extract；

(3) crude extract is cooled down to 22~28 DEG C, is filtered using the filter cloth of 100~200 mesh, and is concentrated to dryness, and is crushed, Sieving, obtains Chinese medical extract.

A kind of external-use skin care preparation that red blood silk effect is removed with Eradicates, during the skin care formulation is as described in claim 1 Medicament extract and skin care item auxiliary material composition.

A kind of Eradicates removes the external-use skin care preparation of red blood silk effect, is made up of the component of following weight percentage：In described Medicament extract 3~8%, jojoba oil 2~5%, wheat-germ oil 1~5%, tristerin 1~4%, cetostearyl alcohol 0.5~3%, allantoin 0.05~0.2%, panthenol 0.2~0.8%, ethoxy urea 0.8~3%, thickener 0.5~1.5%, Sodium Hyaluronate 0.5~1.5%, beta glucan 0.2~0.8%, preservative 0.2~0.5%, surplus are water.

In above-mentioned Chinese medicine composition, extravasated blood that safflower can be dredged in the capillary of red blood silk skin expansion, alleviate red Trace of blood symptom of erythema, repair impaired capillary.

Eucommia ulmoides extracts have proliferation function to vascular endothelial cell, and it plays the role of to strengthen capillary.

Astragalus polyose plays different immunoregulatory activities, these immunoregulation effects as large biological molecule composition Red blood silk scytitis situation can be nursed one's health, effectively alleviates red blood silk skin face inflammation, reduces red blood silk skin wound not Suitable sense.

Horsetail P.E has contraction to capillary, and it is a blood vessel hardening agent, can prevent capillary hemorrhage and Capillary overdistension.

Contain preceding anthocyanidin in grape pip, the histamine release factor can be suppressed.

Herba Dendrobii extract has outstanding moisture holding capacity and can increase the CBF of capillary.

Picrorhiza rhizome has inhibitory action to the activity of angiotensin converting enzyme, angiotensin converting enzyme it is higher Blood pressure will be increased and cause bleeding.

Active component in ivy, rattletop, releives with moisturizing, alleviates sensitive red blood silk scytitis effect, simultaneously Strengthen skin barrier, repair skin epidermis, suppress red blood silk skin histamine release.

Above external medicine composition, each contains the active components of plants of uniqueness, and science is arranged in pairs or groups each composition Ratio, synergy.Start with from red blood silk Crack cause, repair red blood silk skin damage epidermis, while repair red blood silk skin Skin is damaged capillary, and different plant components are directed to red blood silk skin different symptoms, thoroughly solves red blood silk puzzlement.

Beneficial effects of the present invention：

Each medicinal material contains the active components of plants of uniqueness in Chinese medicine composition of the present invention, and science is arranged in pairs or groups each composition Ratio, synergy, there is significant Eradicates the effect of removing red blood trace on face, the Chinese medical extract is applied to external use skin care In, can effectively solve the problems, such as red blood trace on face.The present invention is by Chinese medical extract and the moisturizing that can be filled skin-nourishing Mutually external-use skin care preparation is made to conjunction in component, the effect of can not only reaching Chinese medicine, while simple using reason and do not stimulate Property, the side effects such as allergy, dependence will not be produced.

Embodiment

Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, Obviously, described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.Based in the present invention Embodiment, all other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, all Belong to the scope of protection of the invention.

Embodiment 1

The present embodiment provides a kind of Chinese medical extract that red blood silk effect is removed with Eradicates, is the medicinal material matched by following weight It is made：20 parts of safflower, 20 parts of the bark of eucommia, 20 parts of the Radix Astragali, 25 parts of meadow pine, 5 parts of purple perilla, 35 parts of grape pip, 20 parts of the stem of noble dendrobium, chamomile 4 Part, 5 parts of Radix picrorrhizae, 8 parts of ivy, 4 parts of rattletop.

The present embodiment has Eradicates except the preparation method of the Chinese medical extract of red blood silk effect, comprises the following steps：

(1) each medicinal material is weighed by proportioning；

(2) bulk drug is put into water and decocts water extraction twice, for the first time the part by weight 1 of the medicinal material of extraction and water:15, decoct It is 120min to boil the time, obtains extract solution, and first time is extracted into gained extract solution filters out, and filter residue adds relative 12 times of filter residue weight Water decocted, decocting time is that 90min obtains second of extract solution, and merging extract solution twice, to obtain external application Chinese medicine extract thick Extract；

(3) crude extract is cooled down to 25 DEG C, is filtered using the filter cloth of 100~200 mesh, and is concentrated to dryness, and is crushed, mistake Sieve, obtains Chinese medical extract.

The present embodiment simultaneously provides the external-use skin care preparation that a kind of Eradicates removes red blood silk effect, is by the group of following weight percentage Divide and be made：The Chinese medical extract 5%, jojoba oil 4%, wheat-germ oil 3%, tristerin 2% of the present embodiment, spermaceti Stearyl alcohol 2%, allantoin 0.1%, panthenol 0.5%, ethoxy urea 1.5%, thickener 1.0%, Sodium Hyaluronate 1.0%, β- Glucan 0.5%, preservative 0.3%, surplus are water.

Embodiment 2

The present embodiment provides a kind of Chinese medical extract that red blood silk effect is removed with Eradicates, is the medicinal material matched by following weight It is made：15 parts of safflower, 25 parts of the bark of eucommia, 15 parts of the Radix Astragali, 30 parts of meadow pine, 2 parts of purple perilla, 40 parts of grape pip, 10 parts of the stem of noble dendrobium, chamomile 5 Part, 3 parts of Radix picrorrhizae, 10 parts of ivy, 2 parts of rattletop.

(1) each medicinal material is weighed by proportioning；

(2) bulk drug is put into water and decocts water extraction twice, for the first time the part by weight 1 of the medicinal material of extraction and water:10, decoct It is 180min to boil the time, obtains extract solution, and first time is extracted into gained extract solution filters out, and filter residue adds relative 15 times of filter residue weight Water decocted, decocting time is that 60min obtains second of extract solution, and merging extract solution twice, to obtain external application Chinese medicine extract thick Extract；

(3) crude extract is cooled down to 22 DEG C, is filtered using the filter cloth of 100~200 mesh, and is concentrated to dryness, and is crushed, mistake Sieve, obtains Chinese medical extract.

The present embodiment simultaneously provides the external-use skin care preparation that a kind of Eradicates removes red blood silk effect, is by the group of following weight percentage Divide and be made：The Chinese medical extract 3%, jojoba oil 5%, wheat-germ oil 1%, tristerin 4% of the present embodiment, spermaceti Stearyl alcohol 0.5%, allantoin 0.2%, panthenol 0.2%, ethoxy urea 3%, thickener 0.5%, Sodium Hyaluronate 1.5%, β- Glucan 0.2%, preservative 0.5%, surplus are water.

Embodiment 3

The present embodiment provides a kind of Chinese medical extract that red blood silk effect is removed with Eradicates, is the medicinal material matched by following weight It is made：25 parts of safflower, 15 parts of the bark of eucommia, 25 parts of the Radix Astragali, 20 parts of meadow pine, 8 parts of purple perilla, 30 parts of grape pip, 30 parts of the stem of noble dendrobium, chamomile 3 Part, 8 parts of Radix picrorrhizae, 5 parts of ivy, 6 parts of rattletop.

(1) each medicinal material is weighed by proportioning；

(2) bulk drug is put into water and decocts water extraction twice, for the first time the part by weight 1 of the medicinal material of extraction and water:20, decoct It is 60min to boil the time, obtains extract solution, and first time is extracted into gained extract solution filters out, and filter residue adds relative 8 times of filter residue weight Water is decocted, and decocting time is that 120min obtains second of extract solution, and merging extract solution twice, to obtain external application Chinese medicine extract thick Extract；

(3) crude extract is cooled down to 28 DEG C, is filtered using the filter cloth of 100~200 mesh, and is concentrated to dryness, and is crushed, mistake Sieve, obtains Chinese medical extract.

The present embodiment simultaneously provides the external-use skin care preparation that a kind of Eradicates removes red blood silk effect, is by the group of following weight percentage Divide and be made：The Chinese medical extract 8%, jojoba oil 2%, wheat-germ oil 5%, tristerin 1% of the present embodiment, spermaceti Stearyl alcohol 3%, allantoin 0.05%, panthenol 0.8%, ethoxy urea 0.8%, thickener 1.5%, Sodium Hyaluronate 0.5%, β- Glucan 0.8%, preservative 0.2%, surplus are water.

Embodiment 4

The present embodiment provides a kind of Chinese medical extract that red blood silk effect is removed with Eradicates, is the medicinal material matched by following weight It is made：18 parts of safflower, 22 parts of the bark of eucommia, 18 parts of the Radix Astragali, 28 parts of meadow pine, 3 parts of purple perilla, 38 parts of grape pip, 15 parts of the stem of noble dendrobium, chamomile 5 Part, 6 parts of Radix picrorrhizae, 6 parts of ivy, 8 parts of rattletop.

(1) each medicinal material is weighed by proportioning；

(2) bulk drug is put into water and decocts water extraction twice, for the first time the part by weight 1 of the medicinal material of extraction and water:12, decoct It is 150min to boil the time, obtains extract solution, and first time is extracted into gained extract solution filters out, and filter residue adds relative 10 times of filter residue weight Water decocted, decocting time is that 100min obtains second of extract solution, merges extract solution twice and obtains external application Chinese medicine extract Crude extract；

(3) crude extract is cooled down to 26 DEG C, is filtered using the filter cloth of 100~200 mesh, and is concentrated to dryness, and is crushed, mistake Sieve, obtains Chinese medical extract.

The present embodiment simultaneously provides the external-use skin care preparation that a kind of Eradicates removes red blood silk effect, is by the group of following weight percentage Divide and be made：The Chinese medical extract 6%, jojoba oil 4%, wheat-germ oil 2%, tristerin 3% of the present embodiment, spermaceti Stearyl alcohol 1.0%, allantoin 0.15%, panthenol 0.7%, ethoxy urea 1.2%, thickener 1.2%, Sodium Hyaluronate 1.0%, Beta glucan 0.4%, preservative 0.4%, surplus are water.

Embodiment 5

The present embodiment provides a kind of Chinese medical extract that red blood silk effect is removed with Eradicates, is the medicinal material matched by following weight It is made：22 parts of safflower, 18 parts of the bark of eucommia, 22 parts of the Radix Astragali, 22 parts of meadow pine, 7 parts of purple perilla, 32 parts of grape pip, 25 parts of the stem of noble dendrobium, chamomile 3 Part, 6 parts of Radix picrorrhizae, 6 parts of ivy, 8 parts of rattletop.

(1) each medicinal material is weighed by proportioning；

(2) bulk drug is put into water and decocts water extraction twice, for the first time the part by weight 1 of the medicinal material of extraction and water:18, decoct It is 80min to boil the time, obtains extract solution, and first time is extracted into gained extract solution filters out, and filter residue adds relative 12 times of filter residue weight Water decocted, decocting time is that 80min obtains second of extract solution, and merging extract solution twice, to obtain external application Chinese medicine extract thick Extract；

(3) crude extract is cooled down to 24 DEG C, is filtered using the filter cloth of 100~200 mesh, and is concentrated to dryness, and is crushed, mistake Sieve, obtains Chinese medical extract.

The present embodiment simultaneously provides the external-use skin care preparation that a kind of Eradicates removes red blood silk effect, is by the group of following weight percentage Divide and be made：The Chinese medical extract 7%, jojoba oil 4%, wheat-germ oil 2%, tristerin 2% of the present embodiment, spermaceti Stearyl alcohol 2%, allantoin 0.10%, panthenol 0.3%, ethoxy urea 1.2%, thickener 1.0%, Sodium Hyaluronate 1.0%, β- Glucan 0.4%, preservative 0.4%, surplus are water.

The clinical trial data of embodiment 1：

1.1 study subject：

Female face of 500 ages between 20 to 55 years old during 2013 to 2016 is selected by different type Skin red blood silk patient, wherein, heredity red blood silk 150, stimulated by external environment condition, the sudden-heat that such as produces an unexpected winner, dry environment stimulate Skin produces red blood silk 150, using red blood silk 150 caused by medicine inferior and cosmetics, using caused by hormone ointment Red blood silk 150.

1.2 test method：

After patient per has cleaned skin, it is coated onto skin using external-use skin care preparation made from embodiment 1 and corresponds to affected part, Softly it is massaged into skin to fully absorb, at least keeps skin surface to stop 60min after having massaged.Continuous use 60 days.

1.3 curative effects judge：

Red blood silk whole disappearance person is recovery from illness, and more than 50% person of elimination is remarkable result, and more than 30% person of elimination is effect Effectively, it is DeGrain to eliminate less than 30% person.

1.4 result of the test：

Heredity telangiectasis：Recovery from illness 99, accounts for 66%；Remarkable result 45, accounts for 30%；Effective 3, account for 2.0%；DeGrain 3, accounts for 2.0%.

External environment condition stimulates red blood silk：Recovery from illness 141, accounts for 94%；Remarkable result 6, accounts for 4.0%.Medicine inferior and change Telangiectasis caused by cosmetic：Recovery from illness 150, accounts for 100%.

Red blood silk caused by hormone ointment：Recovery from illness 150, accounts for 100%.

1.5 analysis of statistical data：

Telangiectasis treatment complexity is followed successively by：Heredity, external environment condition stimulate, and medicine and cosmetics inferior draw Rise, hormone ointment causes.

1.6 conclusion：

Above-mentioned clinical test shows that there is external preparation of the invention obvious treatment and maintenance to act on to red blood silk.Though It is so unbalanced to various red blood silk effects, but effective percentage can protect more than 90%.The use of 60 days is simultaneously skin two in this experiment In the individual skin metabolism cycle, the duration is shorter, if continuing half a year or 1 year, it is contemplated that have more preferable effect, ensure all classes The red blood silk of type can fully recover.Meanwhile the various Chinese medicinal plant compositions that the present invention selects, Nantural non-toxic, red blood silk is removed in Eradicates While have good opsonic action to human body skin, aid in skin health.The skin-nourishing agent of addition, it can be carried from various angles For skin-nourishing, promote skin epidermis to thicken, recover the skin natural cover for defense, resistance enhancing, fundamentally treat red blood silk.

The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention God any modification, equivalent substitution and improvements made etc., should be included in the scope of the protection with principle.

Claims

1. a kind of Chinese medical extract that red blood silk effect is removed with Eradicates, it is characterised in that be the medicinal material system matched by following weight Into：15~25 parts of safflower, 15~25 parts of the bark of eucommia, 15~25 parts of the Radix Astragali, 20~30 parts of meadow pine, 2~8 parts of purple perilla, grape pip 30~ 40 parts, 10~30 parts of the stem of noble dendrobium, 3~5 parts of chamomile, 3~8 parts of Radix picrorrhizae, 5~10 parts of ivy, 2~6 parts of rattletop.

2. a kind of Chinese medical extract that red blood silk effect is removed with Eradicates according to claim 1, it is characterised in that be under The medicinal material for stating weight proportion is made：18~22 parts of safflower, 18~22 parts of the bark of eucommia, 18~22 parts of the Radix Astragali, 22~28 parts of meadow pine, purple perilla 3~7 parts, 32~38 parts of grape pip, 15~25 parts of the stem of noble dendrobium, 3~5 parts of chamomile, 4~6 parts of Radix picrorrhizae, 6~8 parts of ivy, rise 3~8 parts of fiber crops.

3. described in a kind of claim 1 or 2 there is Eradicates to exist except the preparation method of the Chinese medical extract of red blood silk effect, its feature In comprising the following steps：

(1) each medicinal material is weighed by proportioning；

(2) bulk drug is put into water and decocts water extraction twice, for the first time the part by weight 1 of the medicinal material of extraction and water:10~1:20, Decocting time is 60~180min, obtains extract solution, and first time is extracted into gained extract solution filters out, and filter residue adds relative filter residue weight The water of 8~15 times of amount is decocted, and decocting time is that 60~120min obtains second of extract solution, is merged extract solution twice and is obtained outside With Chinese medical extract crude extract；

(3) crude extract is cooled down to 22~28 DEG C, is filtered using the filter cloth of 100~200 mesh, and is concentrated to dryness, and is crushed, mistake Sieve, obtains Chinese medical extract.

4. a kind of external-use skin care preparation that red blood silk effect is removed with Eradicates, it is characterised in that the skin care formulation is by claim 3 Described Chinese medical extract and skin care item auxiliary material composition.

5. a kind of Eradicates according to claim 4 removes the external-use skin care preparation of red blood silk effect, it is characterised in that is by following The component of percentage by weight is made：It is the Chinese medical extract 3~8%, jojoba oil 2~5%, wheat-germ oil 1~5%, hard Glycerol 1~4%, cetostearyl alcohol 0.5~3%, allantoin 0.05~0.2%, panthenol 0.2~0.8%, ethoxy urea 0.8~3%, thickener 0.5~1.5%, Sodium Hyaluronate 0.5~1.5%, beta glucan 0.2~0.8%, preservative 0.2~ 0.5%, surplus is water.