CN105456989A - Traditional Chinese medicine for eliminating pain and preparation method of traditional Chinese medicine - Google Patents

Traditional Chinese medicine for eliminating pain and preparation method of traditional Chinese medicine Download PDF

Info

Publication number
CN105456989A
CN105456989A CN201510934316.2A CN201510934316A CN105456989A CN 105456989 A CN105456989 A CN 105456989A CN 201510934316 A CN201510934316 A CN 201510934316A CN 105456989 A CN105456989 A CN 105456989A
Authority
CN
China
Prior art keywords
group
chinese medicine
radix
rhizoma
steam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201510934316.2A
Other languages
Chinese (zh)
Other versions
CN105456989B (en
Inventor
顾璟豪
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201510934316.2A priority Critical patent/CN105456989B/en
Publication of CN105456989A publication Critical patent/CN105456989A/en
Application granted granted Critical
Publication of CN105456989B publication Critical patent/CN105456989B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/24Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8988Gastrodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/902Sparganiaceae (Bur-reed family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

Abstract

The invention relates to traditional Chinese medicine for eliminating pain and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine for eliminating pain is prepared from such raw materials as musk, safflower carthamus, panax notoginseng, dragon's blood, incised notopterygium, ligusticum wallichii, asarum sieboldii, peach kernel, radix angelicae, cassia twig and the like by independently soaking, steaming, fermenting and distilling in groups and mixing. The traditional Chinese medicine disclosed by the invention has beneficial effects that the traditional Chinese medicine for eliminating pain is prepared from natural Chinese herbal medicines through a fermentation process; the traditional Chinese medicine, which can be smeared on or sprayed to an affected part, can rapidly permeate skin so as to accelerate tissue repair, relieve capillary dilation, cell edema, soft tissue injury, local inflammation and like problems, to effectively improve local edema, pain or dermal inflammation, provide nutrition to tissue cell regeneration or soft tissue recovery, offer effective help to bone joint lubrication and cell reconstruction, significantly shorten recovery time in patients with bone and joint diseases and relieve the feeling of pain.

Description

Chinese medicine of eliminate pain and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to Chinese medicine of a kind of eliminate pain and preparation method thereof.
Background technology
Pain is usually by causing the noxious stimulation of tissue injury to cause.The mechanical irritation such as lancinate, rod hits, and electric current, high temperature and the physical chemical factor such as strong acid, highly basic all can become noxious stimulation, some long-term having an intense pain, and have become a kind of insufferable torment to body.When histiocyte inflammation or damage, the bioactive substance such as potassium ion, 5-hydroxy tryptamine, acetylcholine, Kallidin I, histamine be released in extracellular fluid also can cause pain or hyperpathia, the induced pain effect of these chemical substances is greatly strengthened in the existence of impaired Topical Prostaglandin, and the medicine that prostaglandin synthesizes can be suppressed, as aspirin then has analgesic effect, but along with the extensive use of aspirin, its untoward reaction also increases gradually.Therefore, analgesia is the vital task that medical personnel faces.
Summary of the invention
In order to solve the problems referred to above that prior art exists, the invention provides Chinese medicine of a kind of eliminate pain and preparation method thereof.
The technical solution adopted in the present invention is: a kind of Chinese medicine of eliminate pain, comprises following raw material and weight ratio thereof:
First group: Moschus: Flos Carthami: Radix Notoginseng: Sanguis Draxonis: Rhizoma Et Radix Notopterygii: Rhizoma Chuanxiong: Herba Asari: Semen Persicae: the Radix Angelicae Dahuricae: the mixture that Ramulus Cinnamomi forms according to weight ratio 3-5:150-200:80-100:80-100:80-100:80-100:40-50:40-50:40-5 0:40-50;
Second group: Zaocys: Bombyx Batryticatus: Rhizoma Gastrodiae: Caulis Trachelospermi: Caulis Piperis Kadsurae: Cortex Illicii: Radix Saposhnikoviae: the mixture that Radix Angelicae Pubescentis forms according to weight ratio 80-100:80-100:80-100:100-120:100-120:100-120:100-150:80-100;
3rd group: Eupolyphaga Seu Steleophaga: stir-baked SQUAMA MANITIS: Herba Artemisiae Anomalae: Rhizoma Homalomenae: Caulis Impatientis: Radix Clematidis: Radix Gentianae Macrophyllae: Rhizoma Sparganii: Rhizoma Curcumae: Rhizoma Atractylodis: the mixture that Radix Paeoniae Rubra forms according to weight ratio 80-100:10-30:80-100:80-100:80-120:80-120:80-120:50-80:50-80:80-120:80-120;
4th group: Semen Coicis: Fructus Zanthoxyli: Rhizoma Curcumae Longae: Rhizoma Zingiberis Preparatum: Fructus Foeniculi: Radix Puerariae: Semen Coicis: Fructus Zanthoxyli: Rhizoma Curcumae Longae: Rhizoma Zingiberis Preparatum: Fructus Foeniculi: the mixture that Radix Puerariae forms according to weight ratio 300-500:50-100:30-70:40-80:50-90:80-120;
5th group: Borneolum Syntheticum: the mixture that Mentholum forms according to weight ratio 150-300:120-200.
Further, described raw material also comprises the 6th group: the Pseudobulbus Bletillae (Rhizoma Bletillae): Radix Ampelopsis: Radix Angelicae Sinensis: Radix Rehmanniae Preparata: Radix Achyranthis Bidentatae: Radix Dipsaci: Rhizoma Drynariae: the Cortex Eucommiae: Herba Taxilli: Fructus Chaenomelis: the mixture that Cortex Cinnamomi forms according to weight ratio 50-80:50-80:50-80:100-200:80-120:100-150:80-120:80-120:8 0-120:50-80:30-50.
A preparation method for the Chinese medicine of described eliminate pain, comprises the following steps:
(1) soak: the Chinese liquor adding 10-30wt% in the described raw material organize first to fourth by group respectively, soak, make and soak material;
(2) steam: described immersions of each group is expected pull out respectively and to steam respectively afterwards, until well-done, be then cooled to room temperature, make and steam material;
(3) ferment: steam in material described in each group and add distillers yeast and durian peel respectively, then ferment respectively, make fermentation material;
(4) distill: each described fermentation material organized is distilled respectively, make distillation material;
(5) mix: mixed by the raw material of all described distillation material with described 5th group, mix homogeneously gets product the Chinese medicine of eliminate pain.
The described distillation material of first group is mixed into: the described distillation material of second group: the described distillation material of the 3rd group: the described distillation material of the 4th group: the 5th group of described raw material is 2:1:1:2:1 described in step (5).
A preparation method for the Chinese medicine of described eliminate pain, comprises the following steps:
(1) soak: by first, second, third and fourth, the Chinese liquor adding 10-30wt% in the described raw material of six groups by group respectively, soak, make and soak material;
(2) steam: described immersions of each group is expected pull out respectively and to steam respectively afterwards, until well-done, be then cooled to room temperature, make and steam material;
(3) ferment: steam in material described in each group and add distillers yeast and durian peel respectively, then ferment respectively, make fermentation material;
(4) distill: each described fermentation material organized is distilled respectively, make distillation material;
(5) mix: mixed by with described raw material the 5th group of all described distillation material, mix homogeneously gets product the Chinese medicine of eliminate pain.
The described distillation material of first group is mixed into: the described distillation material of second group: the described distillation material of the 3rd group: the described distillation material of the 6th group: the described distillation material of the 4th group: the 5th group of described raw material is 1:1:1:2:2:1,2:2:2:2:2:3,2:1:1:2:2:1,1:1:2:1:3:1.5 or 1:1:1:1:1:1 described in step (5).
Step (3) is carried out again after step (1) and step (2) are repeated 2-3 time successively.
The temperature of soaking described in step (1) is 25-28 DEG C, and the time of described immersion is 6-8 days, and the number of degrees of described Chinese liquor are greater than 50-65 degree.
The temperature steamed described in step (2) is 120-200 DEG C, described in time of steaming be 60-90 minute; The material that steams of distillation described in step (4) accounts for more than 35% of described fermentation material.
The addition of distillers yeast described in step (3) for described in steam the 1-3wt% of material, the time of described fermentation is 15-28 days, 21 days; The temperature of described fermentation is 25-28 DEG C; The addition of described durian peel for described in steam the 3-5wt% of material.
A using method for the Chinese medicine of described eliminate pain, comprises the following steps:
(1) by affected part scrub;
(2) Chinese medicine of described eliminate pain be applied in affected part or be sprayed to affected part.
The Chinese medicine of eliminate pain of the present invention, be mainly that raw material is made through special fermentation manufacturing technique with Chinese herbal medicine, its major function is blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, dredging collateral cold expelling, relaxing muscles and tendons are good for bone, removing toxic substances and promoting tissue regeneration.Its drug main will divide six groups of independent fermentations to form, and effect is specific as follows:
First group of medicine: Moschus, Flos Carthami, Radix Notoginseng, Sanguis Draxonis, Rhizoma Et Radix Notopterygii, Rhizoma Chuanxiong, Herba Asari, Semen Persicae, the Radix Angelicae Dahuricae, Ramulus Cinnamomi.It is mainly with dissipating blood stasis hemostasis, and the Radix Notoginseng of subduing swelling and relieving pain be monarch, and being aided with Semen Persicae, Flos Carthami, Rhizoma Chuanxiong etc. be minister, helps and increases locally pore absorption with the medicine such as Rhizoma Et Radix Notopterygii, Ramulus Cinnamomi, Herba Asari, then the Moschus of walking to alter with fragrance is for making, and sensible health everywhere.
Second group of medicine: Zaocys, Bombyx Batryticatus, Rhizoma Gastrodiae, Caulis Trachelospermi, Caulis Piperis Kadsurae, Cortex Illicii, Radix Saposhnikoviae, Radix Angelicae Pubescentis.It is mainly monarch with Rhizoma Gastrodiae, and Caulis Trachelospermi, Caulis Piperis Kadsurae are minister, and be aided with Radix Saposhnikoviae, Cortex Illicii is assistant, Zaocys, the sensible medicine of Bombyx Batryticatus spasmolytic are for making, and the joint disease making wind demonstrate,prove puzzlement is effectively controlled.
3rd group of medicine: Eupolyphaga Seu Steleophaga, stir-baked SQUAMA MANITIS, Herba Artemisiae Anomalae, Rhizoma Homalomenae, Caulis Impatientis, Radix Clematidis, Radix Gentianae Macrophyllae, Rhizoma Sparganii, Rhizoma Curcumae, Rhizoma Atractylodis, Radix Paeoniae Rubra.Its mainly with Herba Artemisiae Anomalae, Radix Clematidis, Rhizoma Homalomenae for monarch, Radix Gentianae Macrophyllae, Rhizoma Atractylodis are minister, Caulis Impatientis, Rhizoma Sparganii, Rhizoma Curcumae for assistant, Eupolyphaga Seu Steleophaga, stir-baked SQUAMA MANITIS, Radix Paeoniae Rubra are for making, and obtaining upper catharsis to the osteoarthrosis problem caused because of damp syndrome reaches, except the effect of humidifying numbness.
4th group of medicine: the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Ampelopsis, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Radix Achyranthis Bidentatae, Radix Dipsaci, Rhizoma Drynariae, the Cortex Eucommiae, Herba Taxilli, Fructus Chaenomelis, Cortex Cinnamomi.Joint disease can cause osteoarthrosis to lack nutrient for a long time, loose or the disease such as lateral bending, bony spur is following.4th group of medicine is consolidated by medicines such as Radix Dipsaci, Rhizoma Drynariae, Radix Rehmanniae Preparata, the Cortexs Eucommiae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Ampelopsis carry out work to the skin surface problem that local causes because of prolonged sickness blood deficiency etc., utilize the strong local organizations such as Herba Taxilli, Fructus Chaenomelis, Radix Achyranthis Bidentatae simultaneously, be aided with Cortex Cinnamomi warming YANG to expel cold, to solve the osteoarthrosis problem that old complaint causes.
5th group of medicine: Semen Coicis, Fructus Zanthoxyli, Rhizoma Curcumae Longae, Rhizoma Zingiberis Preparatum, Fructus Foeniculi, Radix Puerariae.Main cooperation is four groups of medicines above, reach dehumidifying cold expelling, easing joint movement, warming YANG dredging collateral, effect of promoting blood circulation and stopping pain.Meanwhile, the test of Radix Puerariae extractive matter shows that the skin reparation of his-and-hers watches layer and righting have auxiliary curative effect.Add Radix Puerariae to avoid because walking to alter problem that medicine too causes and having the effect of righting skin Caring.
6th group: Borneolum Syntheticum, Mentholum.For assisted class medicine, mainly utilize its cold and cool stimulation local skin, prevent from turning round local edema that contusion causes or lump is formed.
Extra conductant ingredient durian peel novelly utilizes green product, and current research shows that its biological extraction agent display can activate local cells, increases drug permeability simultaneously.Impel said medicine to enter external spraying, the medicinal liquid of skin surface can rapid osmotic to disease root, by blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, warming YANG dredging collateral, the effect that the medicines such as cold expelling that dehumidify are comprehensive, improves local symptom rapidly.Cure joint disease people up to ten thousand over several years, contusion is turned round to burst and adopts and to dip in material local drug of topical application 5-10 minute the obvious rate of analgesic effect up to 98%.To scapulohumeral periarthritis, shoulder neck pain; Prolapse of lumbar intervertebral disc, lumbago and skelalgia; Sciatica, hyperosteogeny patient in various degree adopts the drug of topical application, local spray medicine respectively or applies ointment and can accelerate healing speed, and the fastest healing time is 2 days, all has good treatment and auxiliary therapeutic action for patients with mild, moderate, patient with severe symptoms.Adopt the ratio of 1:50 to add Bulbus Allii Fistulosi water soaking to (class) rheumatic arthritis patient and have auxiliary therapeutic action.It all has obvious effect to the new and old pain of injury of all kinds of affection of dampness arthralgia due to cold, can also solve other skin diseases such as mosquito bite, skin pruritus.
Beneficial effect of the present invention is: the Chinese medicine of eliminate pain of the present invention adopts multiple natural Chinese medicinal herb to carry out independent immersion by group, steam, fermentation, after distillation process, obtained after the described distillation material obtaining each group being carried out mixing, the Chinese medicine of described eliminate pain is made into herb liquid, can smear or be sprayed at affected part, be prepared from owing to adopting unique fermentation technology, make the Medicine small molecule group effect of described herb liquid obviously, rapid osmotic skin, tissue is impelled to accelerate to repair, alleviate telangiectasis, cellular edema, the problem such as soft tissue injury and local inflammation, effectively improve local edema, pain or top layer inflammation, for histiocyte regeneration or soft tissue recover to provide nutrition, simultaneously its permeability can go directly root, effective help is played to osteoarthrosis lubrication and cellular reconstitution, joint disease patient recovery times obviously shorten, pain alleviates, take effect even then and there, the overwhelming majority rules recurrence rate after healing by men and reduces.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further details.
Embodiment 1
A Chinese medicine for eliminate pain, comprises following raw material:
First group: Moschus 4g, Flos Carthami 180g, Radix Notoginseng 90g, Sanguis Draxonis 90g, Rhizoma Et Radix Notopterygii 90g, Rhizoma Chuanxiong 90g, Herba Asari 45g, Semen Persicae 45g, Radix Angelicae Dahuricae 45g, Ramulus Cinnamomi 45g;
Second group: Zaocys 90g, Bombyx Batryticatus 90g, Rhizoma Gastrodiae 90g, Caulis Trachelospermi 110g, Caulis Piperis Kadsurae 110g, Cortex Illicii 110g, Radix Saposhnikoviae 120g, Radix Angelicae Pubescentis 90g;
3rd group: Eupolyphaga Seu Steleophaga 90g, stir-baked SQUAMA MANITIS 20g, Herba Artemisiae Anomalae 90g, Rhizoma Homalomenae 90g, Caulis Impatientis 100g, Radix Clematidis 100g, Radix Gentianae Macrophyllae 100g, Rhizoma Sparganii 65g, Rhizoma Curcumae 70g, Rhizoma Atractylodis 100g, Radix Paeoniae Rubra 100g;
4th group: Semen Coicis 400g, Fructus Zanthoxyli 75g, Rhizoma Curcumae Longae 50g, Rhizoma Zingiberis Preparatum 60g, Fructus Foeniculi 70g, Radix Puerariae 100g;
5th group: Borneolum Syntheticum 180g, Mentholum 160g.
A preparation method for the Chinese medicine of described eliminate pain, comprises the following steps:
(1) soak: the Chinese liquor adding 20wt% in the described raw material organize first to fourth by group respectively, carry out soaking at room temperature 11 days, make and soak material;
(2) steam: described immersions of each group is expected pull out respectively and to steam respectively afterwards, until well-done, be then cooled to room temperature, make and steam material;
(3) ferment: steam in material described in each group and add 2wt% Angel distillers yeast and 4wt% durian peel respectively, then ferment respectively, make fermentation material;
(4) distill: each described fermentation material organized is distilled respectively, make distillation material;
(5) mix: by all described distillation material in proportion, the described distillation material of first group: the described distillation material of second group: the described distillation material of the 3rd group: the described distillation of the 4th group is expected: the 5th group of described raw material is that 1:1:1:1:1 mixes, mix homogeneously gets product the Chinese medicine of eliminate pain can cure scapulohumeral periarthritis, shoulder and neck.
Embodiment 2
A Chinese medicine for eliminate pain, comprises following raw material:
First group: Moschus 3g, Flos Carthami 200g, Radix Notoginseng 80g, Sanguis Draxonis 80g, Rhizoma Et Radix Notopterygii 80g, Rhizoma Chuanxiong 100g, Herba Asari 50g, Semen Persicae 40g, Radix Angelicae Dahuricae 50g, Ramulus Cinnamomi 40g;
Second group: Zaocys 80g, Bombyx Batryticatus 100g, Rhizoma Gastrodiae 80g, Caulis Trachelospermi 120g, Caulis Piperis Kadsurae 100g, Cortex Illicii 100g, Radix Saposhnikoviae 150g, Radix Angelicae Pubescentis 100g;
3rd group: Eupolyphaga Seu Steleophaga 80g, stir-baked SQUAMA MANITIS 10g, Herba Artemisiae Anomalae 100g, Rhizoma Homalomenae 80g, Caulis Impatientis 120g, Radix Clematidis 80g, Radix Gentianae Macrophyllae 120g, Rhizoma Sparganii 50g, Rhizoma Curcumae 80g, Rhizoma Atractylodis 80g, Radix Paeoniae Rubra 120g;
4th group: Semen Coicis 300g, Fructus Zanthoxyli 100g, Rhizoma Curcumae Longae 30g, Rhizoma Zingiberis Preparatum 80g, Fructus Foeniculi 50g, Radix Puerariae 80g;
5th group: Borneolum Syntheticum 300g, Mentholum 120g.
A preparation method for the Chinese medicine of described eliminate pain, comprises the following steps:
(1) soak: the Chinese liquor adding 10wt% in the described raw material organize first to fourth by group respectively, carry out soaking at room temperature 10 days, make and soak material;
(2) steam: described immersions of each group is expected pull out respectively and to steam respectively afterwards, until well-done, be then cooled to room temperature, make and steam material;
(3) step (1) and step (2) are repeated 2-3 time successively
(4) ferment: steam in material described in each group and add 3wt% Angel distillers yeast and 3wt% durian peel respectively, then ferment respectively, make fermentation material;
(5) distill: each described fermentation material organized is distilled respectively, make distillation material;
(6) mix: by all described distillation material in proportion, the described distillation material of first group: the described distillation material of second group: the described distillation material of the 3rd group: the described distillation of the 4th group is expected: the 5th group of described raw material is that 2:1:1:2:1 mixes, mix homogeneously gets product the Chinese medicine of eliminate pain can cure scapulohumeral periarthritis, shoulder and neck.
Embodiment 3
A Chinese medicine for eliminate pain, comprises following raw material:
First group: Moschus 5g, Flos Carthami 150g, Radix Notoginseng 100g, Sanguis Draxonis 100g, Rhizoma Et Radix Notopterygii 100g, Rhizoma Chuanxiong 80g, Herba Asari 40g, Semen Persicae 50g, Radix Angelicae Dahuricae 40g, Ramulus Cinnamomi 50g;
Second group: Zaocys 100g, Bombyx Batryticatus 80g, Rhizoma Gastrodiae 100g, Caulis Trachelospermi 100g, Caulis Piperis Kadsurae 120g, Cortex Illicii 120g, Radix Saposhnikoviae 100g, Radix Angelicae Pubescentis 80g;
3rd group: Eupolyphaga Seu Steleophaga 100g, stir-baked SQUAMA MANITIS 30g, Herba Artemisiae Anomalae 80g, Rhizoma Homalomenae 100g, Caulis Impatientis 80g, Radix Clematidis 120g, Radix Gentianae Macrophyllae 80g, Rhizoma Sparganii 80g, Rhizoma Curcumae 50g, Rhizoma Atractylodis 120g, Radix Paeoniae Rubra 80g;
4th group: Semen Coicis 500g, Fructus Zanthoxyli 50g, Rhizoma Curcumae Longae 70g, Rhizoma Zingiberis Preparatum 40g, Fructus Foeniculi 90g, Radix Puerariae 120g;
5th group: Borneolum Syntheticum 150g, Mentholum 200g.
A preparation method for the Chinese medicine of described eliminate pain, comprises the following steps:
(1) soak: the Chinese liquor adding 30wt% in the described raw material organize first to fourth by group respectively, carry out soaking at room temperature 5 days, make and soak material;
(2) steam: described immersions of each group is expected pull out respectively and to steam respectively afterwards, until well-done, be then cooled to room temperature, make and steam material;
(3) ferment: steam in material described in each group and add 5wt% Angel distillers yeast and 5wt% durian peel respectively, then ferment respectively, make fermentation material;
(4) distill: each described fermentation material organized is distilled respectively, make distillation material;
(5) mix: by all described distillation material in proportion, the described distillation material of first group: the described distillation material of second group: the described distillation material of the 3rd group: the described distillation of the 4th group is expected: the 5th group of described raw material is that 2:1:1:2:1 mixes, mix homogeneously gets product the Chinese medicine of eliminate pain can cure scapulohumeral periarthritis, shoulder and neck.
Embodiment 4
A Chinese medicine for eliminate pain, comprises following raw material:
First group: Moschus 4g, Flos Carthami 180g, Radix Notoginseng 90g, Sanguis Draxonis 90g, Rhizoma Et Radix Notopterygii 90g, Rhizoma Chuanxiong 90g, Herba Asari 45g, Semen Persicae 45g, Radix Angelicae Dahuricae 45g, Ramulus Cinnamomi 45g;
Second group: Zaocys 90g, Bombyx Batryticatus 90g, Rhizoma Gastrodiae 90g, Caulis Trachelospermi 110g, Caulis Piperis Kadsurae 110g, Cortex Illicii 110g, Radix Saposhnikoviae 120g, Radix Angelicae Pubescentis 90g;
3rd group: Eupolyphaga Seu Steleophaga 90g, stir-baked SQUAMA MANITIS 20g, Herba Artemisiae Anomalae 90g, Rhizoma Homalomenae 90g, Caulis Impatientis 100g, Radix Clematidis 100g, Radix Gentianae Macrophyllae 100g, Rhizoma Sparganii 65g, Rhizoma Curcumae 70g, Rhizoma Atractylodis 100g, Radix Paeoniae Rubra 100g;
4th group: Semen Coicis 400g, Fructus Zanthoxyli 75g, Rhizoma Curcumae Longae 50g, Rhizoma Zingiberis Preparatum 60g, Fructus Foeniculi 70g, Radix Puerariae 100g;
5th group: Borneolum Syntheticum 180g, Mentholum 160g.
A preparation method for the Chinese medicine of described eliminate pain, comprises the following steps:
(1) soak: the Chinese liquor adding 20wt% in the described raw material organize first to fourth by group respectively, carry out soaking at room temperature 10 days, make and soak material;
(2) steam: described immersions of each group is expected pull out respectively and to steam respectively afterwards, until well-done, be then cooled to room temperature, make and steam material;
(3) ferment: described in each group, steam the Harbin adding 6wt% in material respectively potent biological distillers yeast and 3wt% durian peel, then ferment respectively, make fermentation material;
(4) distill: each described fermentation material organized is distilled respectively, make distillation material;
(5) mix: by all described distillation material in proportion, the described distillation material of first group: the described distillation material of second group: the described distillation material of the 3rd group: the described distillation of the 4th group is expected: the 5th group of described raw material is that 1:1:1:2:2:1 mixes, the get product Chinese medicine of eliminate pain of mix homogeneously has good therapeutic effect to prolapse of lumbar intervertebral disc, bulging.
Embodiment 5
A Chinese medicine for eliminate pain, comprises following raw material:
First group: Moschus 3g, Flos Carthami 200g, Radix Notoginseng 80g, Sanguis Draxonis 80g, Rhizoma Et Radix Notopterygii 80g, Rhizoma Chuanxiong 100g, Herba Asari 50g, Semen Persicae 40g, Radix Angelicae Dahuricae 50g, Ramulus Cinnamomi 40g;
Second group: Zaocys 80g, Bombyx Batryticatus 100g, Rhizoma Gastrodiae 80g, Caulis Trachelospermi 120g, Caulis Piperis Kadsurae 100g, Cortex Illicii 100g, Radix Saposhnikoviae 150g, Radix Angelicae Pubescentis 100g;
3rd group: Eupolyphaga Seu Steleophaga 80g, stir-baked SQUAMA MANITIS 10g, Herba Artemisiae Anomalae 100g, Rhizoma Homalomenae 80g, Caulis Impatientis 120g, Radix Clematidis 80g, Radix Gentianae Macrophyllae 120g, Rhizoma Sparganii 50g, Rhizoma Curcumae 80g, Rhizoma Atractylodis 80g, Radix Paeoniae Rubra 120g;
4th group: Semen Coicis 300g, Fructus Zanthoxyli 100g, Rhizoma Curcumae Longae 30g, Rhizoma Zingiberis Preparatum 80g, Fructus Foeniculi 50g, Radix Puerariae 80g;
5th group: Borneolum Syntheticum 300g, Mentholum 120g.
A preparation method for the Chinese medicine of described eliminate pain, comprises the following steps:
(1) soak: the 60 degree of Chinese liquor adding 10wt% in the described raw material organize first to fourth by group respectively, 26 DEG C are carried out immersion 7 days, make and soak material;
(2) steam: described immersions of each group expected to pull out respectively and to steam respectively afterwards, the temperature steamed is 120 DEG C, described in time of steaming be 60 minutes, until well-done, be then cooled to room temperature, make and steam material;
(3) ferment: steam in material described in each group and add the Angel distillers yeast steaming material 3wt% and the durian peel steaming material 4wt% respectively, then ferment respectively, the time of fermentation is 21 days, and the temperature of described fermentation is 25 DEG C, makes fermentation material;
(4) distill: each described fermentation material organized is distilled respectively, steam that thing accounts for described fermentation material 55% of distillation, make distillation material;
(5) mix: by all described distillation material in proportion, the described distillation material of first group: the described distillation material of second group: the described distillation material of the 3rd group: the described distillation material of the 4th group: the 5th group of described raw material is that 2:2:2:2:2:3 mixes, mix homogeneously gets product the Chinese medicine of eliminate pain, and to pulling, there is good therapeutic effect at the initial stage of spraining.
Embodiment 6
A Chinese medicine for eliminate pain, comprises following raw material:
First group: Moschus 5g, Flos Carthami 150g, Radix Notoginseng 100g, Sanguis Draxonis 100g, Rhizoma Et Radix Notopterygii 100g, Rhizoma Chuanxiong 80g, Herba Asari 40g, Semen Persicae 50g, Radix Angelicae Dahuricae 40g, Ramulus Cinnamomi 50g;
Second group: Zaocys 100g, Bombyx Batryticatus 80g, Rhizoma Gastrodiae 100g, Caulis Trachelospermi 100g, Caulis Piperis Kadsurae 120g, Cortex Illicii 120g, Radix Saposhnikoviae 100g, Radix Angelicae Pubescentis 80g;
3rd group: Eupolyphaga Seu Steleophaga 100g, stir-baked SQUAMA MANITIS 30g, Herba Artemisiae Anomalae 80g, Rhizoma Homalomenae 100g, Caulis Impatientis 80g, Radix Clematidis 120g, Radix Gentianae Macrophyllae 80g, Rhizoma Sparganii 80g, Rhizoma Curcumae 50g, Rhizoma Atractylodis 120g, Radix Paeoniae Rubra 80g;
4th group: Pseudobulbus Bletillae (Rhizoma Bletillae) 50-80g, Radix Ampelopsis 50-80g, Radix Angelicae Sinensis 50-80g, Radix Rehmanniae Preparata 100-200g, Radix Achyranthis Bidentatae 80-120g, Radix Dipsaci 100-150g, Rhizoma Drynariae 80-120g, Cortex Eucommiae 80-120g, Herba Taxilli 80-120g, Fructus Chaenomelis 50-80g, Cortex Cinnamomi 30-50g;
5th group: Semen Coicis 500g, Fructus Zanthoxyli 50g, Rhizoma Curcumae Longae 70g, Rhizoma Zingiberis Preparatum 40g, Fructus Foeniculi 90g, Radix Puerariae 120g;
6th group: Borneolum Syntheticum 150g, Mentholum 200g.
A preparation method for the Chinese medicine of described eliminate pain, comprises the following steps:
(1) soak: by adding 65 degree of Chinese liquor of 30wt% in the described raw material of the first to five group respectively by group, soak, 25 DEG C are soaked 6 days, make and soak material;
(2) steam: described immersions of each group expected to pull out respectively and to steam respectively afterwards, the temperature steamed is 160 DEG C, and the time steamed is 75 minutes, until well-done, is then cooled to room temperature, makes and steam material;
(3) step (1) and step (2) are repeated 2-3 time successively;
(4) ferment: steam the potent biological distillers yeast in the Harbin adding the 4wt% steaming material in material respectively and steam the 5wt% durian peel of material described in each group, then ferment respectively, the time of fermentation is 28 days, and the temperature of fermentation is 27 DEG C, makes fermentation material;
(5) distill: each described fermentation material organized is distilled respectively, steam that thing accounts for described fermentation material 45% of distillation, make distillation material;
(6) mix: by all described distillation material in proportion, the described distillation material of first group: the described distillation material of second group: the described distillation material of the 3rd group: the described distillation material of the 4th group: the described distillation material of the 5th group: the 6th group of described raw material is that 2:1:1:2:2:1 mixes, mix homogeneously gets product the Chinese medicine of eliminate pain, has good therapeutic effect to turning round the contusion intermediary and later stages.
Embodiment 7
A Chinese medicine for eliminate pain, comprises following raw material:
First group: Moschus 3g, Flos Carthami 200g, Radix Notoginseng 80g, Sanguis Draxonis 80g, Rhizoma Et Radix Notopterygii 80g, Rhizoma Chuanxiong 100g, Herba Asari 50g, Semen Persicae 40g, Radix Angelicae Dahuricae 50g, Ramulus Cinnamomi 40g;
Second group: Zaocys 80g, Bombyx Batryticatus 100g, Rhizoma Gastrodiae 80g, Caulis Trachelospermi 120g, Caulis Piperis Kadsurae 100g, Cortex Illicii 100g, Radix Saposhnikoviae 150g, Radix Angelicae Pubescentis 100g;
3rd group: Eupolyphaga Seu Steleophaga 80g, stir-baked SQUAMA MANITIS 10g, Herba Artemisiae Anomalae 100g, Rhizoma Homalomenae 80g, Caulis Impatientis 120g, Radix Clematidis 80g, Radix Gentianae Macrophyllae 120g, Rhizoma Sparganii 50g, Rhizoma Curcumae 80g, Rhizoma Atractylodis 80g, Radix Paeoniae Rubra 120g;
4th group: Pseudobulbus Bletillae (Rhizoma Bletillae) 50-80g, Radix Ampelopsis 50-80g, Radix Angelicae Sinensis 50-80g, Radix Rehmanniae Preparata 100-200g, Radix Achyranthis Bidentatae 80-120g, Radix Dipsaci 100-150g, Rhizoma Drynariae 80-120g, Cortex Eucommiae 80-120g, Herba Taxilli 80-120g, Fructus Chaenomelis 50-80g, Cortex Cinnamomi 30-50g;
5th group: Semen Coicis 300-500g, Fructus Zanthoxyli 50-100g, Rhizoma Curcumae Longae 30-70g, Rhizoma Zingiberis Preparatum 40-80g, Fructus Foeniculi 50-90g, Radix Puerariae 80-120g;
6th group: Borneolum Syntheticum 150-300g, Mentholum 120-200g.
A preparation method for the Chinese medicine of described eliminate pain, comprises the following steps:
(1) soak: by first, second, third and fourth, the Chinese liquor of 50 degree adding 20wt% in the described raw material of five groups by group respectively, soak, the temperature of described immersion is 28 DEG C, and the time of described immersion is 8 days, makes to soak and expects;
(2) steam: described immersions of each group is expected pull out respectively and to steam respectively afterwards, described in the temperature that steams be 200 DEG C, described in time of steaming be 90 minutes, until well-done, be then cooled to room temperature, make and steam material;
(3) ferment: steam in material described in each group described in adding respectively and steam the 1wt% Angel distillers yeast of material and the described 3wt% durian peel steaming material, then carry out fermentation 15 days respectively, the temperature of described fermentation is 28 DEG C, makes fermentation material;
(4) distill: each described fermentation material organized is distilled respectively, steam that thing accounts for described fermentation material 35% of described distillation, make distillation material;
(5) mix: mixed by 2:2:4:2:6:3 by with described raw material the 6th group of all described distillation material, the get product Chinese medicine of eliminate pain of mix homogeneously can treat rheumatic arthritis.
All need mix according to the standard of (5) step mixing in the preparation process of embodiments of the invention, if a certain group of needs more distill material, then need to double preparation by group.
A using method for the Chinese medicine of described eliminate pain, comprises the following steps:
(1) by affected part scrub;
(2) Chinese medicine of described eliminate pain be applied in affected part or be sprayed to affected part.
The Chinese medicine cure rate of eliminate pain of the present invention is 86%, and effective percentage is 98%.
Model case is as follows:
Case:
1, shut out certain, Zhejiang Dongyang people from county, 56 years old, bony spur pain is liied in bed, and dips in material external application affected part 20 minutes, 2-3 time on the one, within second day, just can leave the bed and walk about, use Chinese medicine described in embodiment 1 with the Chinese medicine of eliminate pain.
2, money, Shanghai people, 53 years old, prolapse of lumbar intervertebral disc, cannot stand, spray (putting on the skin) agent with the Chinese medicine of eliminate pain and dip in external application affected part 15 minutes after material microwave heating, 3-4 time on the one, tying up belt after 3 days can be suitably movable, uses spray instead and puts 5-6 time on the one on the skin, fully recover after 5 days, use Chinese medicine described in embodiment 4.
3, Zhang, people from Zaozhuang, Shandong, 23 years old, during Basketball Match, leg was sprained, and used the Chinese medicine of eliminate pain to spray (putting on the skin) agent immediately and sprayed continuously 15 seconds, have a rest and recover to enter the court after movable ankle after 1 minute, used Chinese medicine described in embodiment 5.
4, Wang, people from Harbin, 64 years old, joint disease many decades, every day, chronic problem was ached obviously, often took tablet for alleviating pain day by day, with the Chinese medicine of eliminate pain of the present invention, every day 5-6 time, each spray medicine 2-3 time, within 3rd, have clear improvement, stop tablet for alleviating pain after 15 days, basic recovery was normal afterwards on 50th, spray medicine changes each 2-3 time, each 1-2 time, fully recovers after 100 days, pay a return visit and not yet recur, use Chinese medicine described in embodiment 4.
The present invention is not limited to above-mentioned preferred forms; anyone can draw other various forms of products under enlightenment of the present invention; no matter but any change is done in its shape or structure; every have identical with the application or akin technical scheme, all drops within protection scope of the present invention.

Claims (10)

1. a Chinese medicine for eliminate pain, is characterized in that: comprise following raw material:
First group: Moschus: Flos Carthami: Radix Notoginseng: Sanguis Draxonis: Rhizoma Et Radix Notopterygii: Rhizoma Chuanxiong: Herba Asari: Semen Persicae: the Radix Angelicae Dahuricae: the mixture that Ramulus Cinnamomi forms according to weight ratio 3-5:150-200:80-100:80-100:80-100:80-100:40-50:40-50:40-5 0:40-50;
Second group: Zaocys: Bombyx Batryticatus: Rhizoma Gastrodiae: Caulis Trachelospermi: Caulis Piperis Kadsurae: Cortex Illicii: Radix Saposhnikoviae: the mixture that Radix Angelicae Pubescentis forms according to weight ratio 80-100:80-100:80-100:100-120:100-120:100-120:100-150:80-100;
3rd group: Eupolyphaga Seu Steleophaga: stir-baked SQUAMA MANITIS: Herba Artemisiae Anomalae: Rhizoma Homalomenae: Caulis Impatientis: Radix Clematidis: Radix Gentianae Macrophyllae: Rhizoma Sparganii: Rhizoma Curcumae: Rhizoma Atractylodis: the mixture that Radix Paeoniae Rubra forms according to weight ratio 80-100:10-30:80-100:80-100:80-120:80-120:80-120:50-80:50-80:80-120:80-120;
4th group: Semen Coicis: Fructus Zanthoxyli: Rhizoma Curcumae Longae: Rhizoma Zingiberis Preparatum: Fructus Foeniculi: Radix Puerariae: Semen Coicis: Fructus Zanthoxyli: Rhizoma Curcumae Longae: Rhizoma Zingiberis Preparatum: Fructus Foeniculi: the mixture that Radix Puerariae forms according to weight ratio 300-500:50-100:30-70:40-80:50-90:80-120;
5th group: Borneolum Syntheticum: the mixture that Mentholum forms according to weight ratio 150-300:120-200.
2. the Chinese medicine of eliminate pain according to claim 1, is characterized in that: described raw material also comprises the 6th group: the Pseudobulbus Bletillae (Rhizoma Bletillae): Radix Ampelopsis: Radix Angelicae Sinensis: Radix Rehmanniae Preparata: Radix Achyranthis Bidentatae: Radix Dipsaci: Rhizoma Drynariae: the Cortex Eucommiae: Herba Taxilli: Fructus Chaenomelis: the mixture that Cortex Cinnamomi forms according to weight ratio 50-80:50-80:50-80:100-200:80-120:100-150:80-120:80-120:8 0-120:50-80:30-50.
3. a preparation method for the Chinese medicine of eliminate pain as claimed in claim 1, is characterized in that: comprise the following steps:
(1) soak: the Chinese liquor adding 10-30wt% in described first group, second group, the 3rd group, the 4th group raw material respectively, soak, make the immersion material of each group;
(2) steam: pull out respectively to steam often organizing described immersion material respectively afterwards, until well-done, be then cooled to room temperature, obtain each group steam material;
(3) ferment: steam in material described in often organizing and add distillers yeast and durian peel respectively, then ferment respectively, make the fermentation material of each group;
(4) distill: distilling often organizing described fermentation material respectively, making the distillation material of each group;
(5) mix: mixed with the 5th group of described raw material by the described distillation material of each group, mix homogeneously gets product the Chinese medicine of eliminate pain.
4. the preparation method of the Chinese medicine of eliminate pain according to claim 3, it is characterized in that: when carrying out described mixing in step (5), the described distillation material of first group: the described distillation material of second group: the described distillation material of the 3rd group: the described distillation material of the 4th group: the ratio of the weight of the 5th group of described raw material is 2:1:1:2:1.
5. a preparation method for the Chinese medicine of eliminate pain as claimed in claim 2, is characterized in that: comprise the following steps:
(1) soak: the Chinese liquor adding 10-30wt% in described first group, second group, the 3rd group, the 4th group, the 6th group raw material respectively, soak, make and soak material;
(2) steam: pull out respectively to steam often organizing described immersion material respectively afterwards, until well-done, be then cooled to room temperature, obtain each group steam material;
(3) ferment: steam in material described in often organizing and add distillers yeast and durian peel respectively, then ferment respectively, make the fermentation material of each group;
(4) distill: distilling often organizing described fermentation material respectively, making the distillation material of each group;
(5) mix: mixed with the 5th group of described raw material by the described distillation material of each group, mix homogeneously gets product the Chinese medicine of eliminate pain.
6. the preparation method of the Chinese medicine of eliminate pain according to claim 5, is characterized in that: the described distillation material being mixed into first group described in step (5): the described distillation material of second group: the described distillation material of the 3rd group: the described distillation material of the 6th group: the described distillation material of the 4th group: the 5th group of described raw material is 1:1:1:2:2:1,2:2:2:2:2:3,2:1:1:2:2:1,1:1:2:1:3:1.5 or 1:1:1:1:1:1.
7. the preparation method of the Chinese medicine of the eliminate pain according to claim 3 or 5, is characterized in that: carry out step (3) again after step (1) ~ step (2) is repeated 2-3 time.
8. the preparation method of the Chinese medicine of the eliminate pain according to claim 3 or 5, is characterized in that: the temperature of soaking described in step (1) is 25-28 DEG C, and the time of described immersion is 6-8 days, and the ethanol number of degrees of described Chinese liquor are 50-65 degree.
9. the preparation method of the Chinese medicine of the eliminate pain according to claim 3 or 5, is characterized in that: the temperature steamed described in step (2) is 120-200 DEG C, described in time of steaming be 60-90 minute; That distills described in step (4) steams more than the 35wt% that material accounts for described fermentation material.
10. the preparation method of the Chinese medicine of the eliminate pain according to claim 3 or 5, is characterized in that: the addition of distillers yeast described in step (3) for described in steam the 1-3wt% of material, the time of described fermentation is 15-28 days; The temperature of described fermentation is 25-28 DEG C; The addition of described durian peel for described in steam the 3-5wt% of material.
CN201510934316.2A 2015-12-14 2015-12-14 Chinese medicine for eliminating pain and its preparation method Active CN105456989B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510934316.2A CN105456989B (en) 2015-12-14 2015-12-14 Chinese medicine for eliminating pain and its preparation method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510934316.2A CN105456989B (en) 2015-12-14 2015-12-14 Chinese medicine for eliminating pain and its preparation method

Publications (2)

Publication Number Publication Date
CN105456989A true CN105456989A (en) 2016-04-06
CN105456989B CN105456989B (en) 2019-12-24

Family

ID=55595437

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510934316.2A Active CN105456989B (en) 2015-12-14 2015-12-14 Chinese medicine for eliminating pain and its preparation method

Country Status (1)

Country Link
CN (1) CN105456989B (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853657A (en) * 2016-06-06 2016-08-17 侯文平 External-application traditional Chinese medicine for improvement and reunion of ligaments and muscles and using method thereof
CN105943887A (en) * 2016-06-17 2016-09-21 张庆西 Liquid plaster for treating pain and preparation method
CN106421540A (en) * 2016-12-28 2017-02-22 四川默森药业有限公司 Patch for soft tissue damage and preparation method of patch
CN107693647A (en) * 2017-10-20 2018-02-16 何超 A kind of anti-inflammatory, the Chinese medicine composition of detumescence
CN108653704A (en) * 2018-07-17 2018-10-16 重庆市御灵指健康管理有限公司 A kind of lotion and preparation method thereof with anti-inflammatory analgetic function
CN109984339A (en) * 2019-05-09 2019-07-09 参之道(通化)生物科技有限公司 A kind of red ginseng rose honey ointment and preparation method thereof
CN110050927A (en) * 2019-05-09 2019-07-26 参之道(通化)生物科技有限公司 A kind of black ginseng drink and preparation method thereof
CN110882368A (en) * 2018-09-06 2020-03-17 侯明宇 Targeted repair powder for treating neck, shoulder, waist and leg pain and preparation method thereof
CN115581724A (en) * 2022-10-20 2023-01-10 广州百奥格林生物科技有限公司 Preparation method and system of traditional Chinese medicine compound preparation for treating rheumatoid arthritis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101264256A (en) * 2008-04-26 2008-09-17 朱序金 Chinese medicine capsule for treating intractable pain
CN103784667A (en) * 2014-03-04 2014-05-14 邓飞武 Externally-used Chinese herbal medicine liquor for treating rheumatoidbone disease and preparation and usage method thereof
CN103990036A (en) * 2014-05-29 2014-08-20 周慧婷 Traditional Chinese medicine composition for relieving menstrual pain and preparation method and application thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101264256A (en) * 2008-04-26 2008-09-17 朱序金 Chinese medicine capsule for treating intractable pain
CN103784667A (en) * 2014-03-04 2014-05-14 邓飞武 Externally-used Chinese herbal medicine liquor for treating rheumatoidbone disease and preparation and usage method thereof
CN103990036A (en) * 2014-05-29 2014-08-20 周慧婷 Traditional Chinese medicine composition for relieving menstrual pain and preparation method and application thereof

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853657A (en) * 2016-06-06 2016-08-17 侯文平 External-application traditional Chinese medicine for improvement and reunion of ligaments and muscles and using method thereof
CN105943887A (en) * 2016-06-17 2016-09-21 张庆西 Liquid plaster for treating pain and preparation method
CN106421540A (en) * 2016-12-28 2017-02-22 四川默森药业有限公司 Patch for soft tissue damage and preparation method of patch
CN107693647A (en) * 2017-10-20 2018-02-16 何超 A kind of anti-inflammatory, the Chinese medicine composition of detumescence
CN108653704A (en) * 2018-07-17 2018-10-16 重庆市御灵指健康管理有限公司 A kind of lotion and preparation method thereof with anti-inflammatory analgetic function
CN110882368A (en) * 2018-09-06 2020-03-17 侯明宇 Targeted repair powder for treating neck, shoulder, waist and leg pain and preparation method thereof
CN109984339A (en) * 2019-05-09 2019-07-09 参之道(通化)生物科技有限公司 A kind of red ginseng rose honey ointment and preparation method thereof
CN110050927A (en) * 2019-05-09 2019-07-26 参之道(通化)生物科技有限公司 A kind of black ginseng drink and preparation method thereof
CN115581724A (en) * 2022-10-20 2023-01-10 广州百奥格林生物科技有限公司 Preparation method and system of traditional Chinese medicine compound preparation for treating rheumatoid arthritis

Also Published As

Publication number Publication date
CN105456989B (en) 2019-12-24

Similar Documents

Publication Publication Date Title
CN105456989A (en) Traditional Chinese medicine for eliminating pain and preparation method of traditional Chinese medicine
CN103156972B (en) Traditional Chinese medicine combination for treating fracture, hairline fracture and traumatic injury
CN104940796A (en) Traditional Chinese medicine composition for promoting blood circulation to remove blood stasis and relieving swelling and pain
CN102228485B (en) Composition for burn rehabilitation and preparation method thereof
CN101757313B (en) Liquid medicine
CN103191353A (en) Traditional Chinese medicine composition for treating tinea pedis and tinea manus
CN101085327A (en) Traditional Chinese medicine cutaneous permeable agent
CN1322885C (en) Plaster medicine composition with multiple purpose for treating affection pain due to dampness
CN102949680B (en) Medicinal liquor for treating cervical spondylosis and preparation method thereof
CN104383445A (en) Traumatic injury analgesic
CN101199798A (en) Pressurized spray for treating rheumatism ache
CN104547747A (en) Fast-acting medicinal liquor for treating wind-cold-dampness arthralgia and application thereof
CN101601767A (en) A kind of Chinese medicine lotion for the treatment of calcaneodynia
CN106668782A (en) External traditional Chinese medicine preparation for treating knee osteoarthritis and preparation method thereof
CN104873615A (en) Cinnamon oil containing externally applied medicine for treating traumatic injury
CN102949507B (en) Traditional Chinese medicine lotion for treating lumbocrural pain and preparation method thereof
CN102441131A (en) Chinese medicinal composition for treating traumatic injury
CN101108235A (en) Medicament treating acne, comedo and method of preparing the same
CN1090502C (en) External use tradtional Chinese Medicine for treating hyperosteogeny, prolapse of lumbar intervertebral disc and various soft tissue injuries
CN1089492A (en) The herb medicinal paste for external application of treatment hyperosteogeny
CN109718334A (en) A kind of emplastrum production method for rheumatism bone disease and neck-shoulder pain, lumbago and leg pain
CN107890561A (en) A kind of Linimentum of Chinese herbal medicine for being used to treat nettle rash
CN105560427A (en) Transdermal gate-freeing powder
CN1559574A (en) External used Chinese medicine for pain stopping
CN105079394A (en) Pharmaceutic preparation for treating arrhythmia

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant