CN103990036A - Traditional Chinese medicine composition for relieving menstrual pain and preparation method and application thereof - Google Patents
Traditional Chinese medicine composition for relieving menstrual pain and preparation method and application thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for relieving menstrual pain. The traditional Chinese medicine composition comprises the following components in parts by weight: 10 to 20 parts of angelica sinensis, 8 to 12 parts of leonurus, 15 to 25 parts of safflower carthamus, 15 to 25 parts of saussurea involucrate, 15 to 25 parts of folium artemisiae argyi, 25 to 35 parts of radix sophorae flavescentis, 15 to 25 parts of rhizoma atractylodis, 10 to 20 parts of rhodiola rosea, 16 to 28 parts of fructus cnidii, 10 to 15 parts of rhizoma acori graminei, 5 to 10 parts of groundsel, 15 to 25 parts of cortex phellodendri, 25 to 35 parts of radix stemonae, 6 to 10 parts of borneol, and 8 to 12 parts of menthol. The invention also relates to a preparation method of the traditional Chinese medicine composition. The preparation method comprises the following steps: heating and decocting traditional Chinese medicines by grade; separating the leaves; then concentrating the liquid to obtain the traditional Chinese medicine composition. The traditional Chinese medicine composition can be used for preparing hygienic products, and is applicable to treatment of spasmodic pain in hypogastrium, menstrual disorder, abdominal distension, lumbago, general malaise and other symptoms occurring before, after or during menstruation.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and its preparation method and application, especially relate to a kind of for alleviating Chinese medicine composition of pain in menstrual period and its preparation method and application.
Background technology
Dysmenorrhea is the common symptom of a kind of women, refer to before and after menstrual period or between menstrual period and occur lower abdomen spasmic pain, menstrual period, pain person was up to 71.6%, with phenomenons such as menoxenia, menoxenia, abdominal distention, lumbago, general malaises, can be divided into primary dysmenorrhea and secondary dysmenorrhea, Chang Bingfa infertile and endometriosis, uterine adenomyosis and urogenital tract infection.The medicine of existing alleviation pain in menstrual period has oral drugs, liniment etc., but due to the impact of living environment, working environment, uses very inconveniently, is also difficult for reaching the curative effect of expection.
Summary of the invention
In order to address the above problem, the invention provides a kind of is with convenient, eutherapeutic a kind of for alleviating the Chinese medicine composition of pain in menstrual period, and the present invention simultaneously also provides this for alleviating the preparation method and application of Chinese medicine composition of pain in menstrual period.
For addressing the above problem, the technical solution adopted in the present invention is as follows:
For alleviating a Chinese medicine composition for pain in menstrual period, made by following component by weight: Radix Angelicae Sinensis 10-20 part; Herba Leonuri 8-12 part; Flos Carthami 15-25 part; Herba Saussureae Involueratae 15-25 part; Folium Artemisiae Argyi 15-25 part; Radix Sophorae Flavescentis 25-35 part; Rhizoma Atractylodis 15-25 part; Radix Rhodiolae 10-20 part; Fructus Cnidii 16-28 part; Rhizoma Acori Graminei 10-15 part; Herba Senecionis Scandentis 5-10 part; Cortex Phellodendri: 15-25 part; Radix Stemonae 25-35 part; Borneolum Syntheticum 6-10 part; Mentholum 8-12 part.
Radix Angelicae Sinensis: Shennong's Herbal Compendium of Material Medica, its function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia etc.
Herba Leonuri: Compendium of Material Medica: invigorate blood circulation, removing blood stasis, regulating menstruation, removing toxic substances." it is former that book on Chinese herbal medicine is asked ": heat clearing away, removing heat from blood, removing toxic substances, its effect: activating blood and removing stasis, the regulating menstruation water that disappears, abdominalgia with blood stasis etc.
Herba Saussureae Involueratae: exotic flowers and rare herbs rare to see are also rare Tibetan medicines world-famous, its effect: promoting blood flow to regulate menstruation, menoxenia, heat-clearing and toxic substances removing, reducing swelling and alleviating pain etc.
Flos Carthami: prescription is collected " Zhu Shi Ji Yan hospital ", " Waitai Miyao Fang ", Holy Benevolent Prescriptions, " Yunnan Chinese herbal medicine " etc., its effect: the dysmenorrhea of invigorating blood circulation, amenorrhea, dysmenorrhea, gynaecological disease etc.
Folium Artemisiae Argyi: Compendium of Material Medica has another name called Dendrobium denneanum Kerr., " it is former that book on Chinese herbal medicine is asked " has another name called sweet Chinese mugwort, for women's deficiency and coldness, menoxenia, stomachache has obvious curative effects, is a kind of gynecological good medicine, its effect: menoxenia, dysmenorrhea, hypogastralgia, has warming the meridian for stopping bleeding, effect of dispersing cold for relieving pain etc.
Radix Sophorae Flavescentis: there is heat-clearing and toxic substances removing, the function of anti-inflammation, to Propiobacterium, staphylococcus aureus, escherichia coli all have inhibitory action.All there is discussion in each families such as Compendium of Material Medica, " book on Chinese herbal medicine converges and says ", " book on Chinese herbal medicine is through hundred kinds of records ", Shennong's Herbal, " property of medicine opinion ".
Rhizoma Atractylodis: mainly have oxygen lack resistant function, antibiosis and antiviral functions is all documented in the works such as " Elementary Medicine ", " book on Chinese herbal medicine just ", Compendium of Material Medica, " medicine origin ".
Radix Rhodiolae: for blood-enriching and blood-promoting circulation, hemostasia and detumescence, effect of QI invigorating QI invigorating, Ancient Times in China First medical science ancient books and records Shennong's Herbal, hides the Four-Volume Medical Code, all on the books in Ming Dynasty's Compendium of Material Medica, " middle traditional Chinese medicines guiding principle complete works ", " Chinese Pharmacopoeia ".
Fructus Cnidii: " Bencao Jingshu ", " book on Chinese herbal medicine is newly organized ", " book on Chinese herbal medicine justice " etc. have detailed annotation, are mainly used in women's pudendal pruritus, vulval eczema, arthralgia chiefly caused by damp pathogen lumbago etc.
Rhizoma Acori Graminei: be mainly used in regulating the flow of vital energy, invigorate blood circulation, loose wind, damp eliminating, stomachache etc., essentials of Matea Medica, " the southern regions of the Yunnan Province book on Chinese herbal medicine " etc. also have record.
Herba Senecionis Scandentis: effect heat-clearing and toxic substances removing, killing parasites for relieving itching, antibacterial action, " Jiangxi traditional herbal medicine " etc. has record.
Cortex Phellodendri: effect heat clearing away, dampness, eliminating fire and detoxication, the works such as " Bencao Jingshu ", " not Lu ", " pearl sac ", " property of medicine opinion " has description.
The Radix Stemonae: source Collective Notes to the Canon of Materia medica is mainly used in eczema, dermatitis, heat radiation, parasite killing etc., " book on Chinese herbal medicine is newly organized ", " book on Chinese herbal medicine is stated " etc. are on the books.
Borneolum Syntheticum: the loose poison of main effect heat clearing away, loose fire removing toxic substances, reducing swelling and alleviating pain, Compendium of Material Medica, " not Lu ", essentials of Matea Medica etc. have detailed annotation.
Mentholum: act on skin or mucosa, have refrigerant antipruritic, the effect of local analgesia, blood circulation promoting, antiinflammatory, the effects such as heat radiation.
The present invention is based on Chinese medicine medical science to Gynecological Pain through aspect pathogenetic understanding and Therapeutic Principle, according to ancient Chinese medicine pharmacy theoretical reference modern pharmacological research, from Chinese medicine material treasure-house, filter out there is circulation of qi promoting, invigorate blood circulation, the natural drug of the effect such as regulating menstruation, calmness, pain relieving, heat clearing away, removing toxic substances, antiinflammatory, combine according to theory of Chinese medical science, thereby each herbal medicine synergism is given full play to the activity of medicine, thereby promote the effect of medicine; In medicine of the present invention, each taste is crude drug, meeting the traditional Chinese medical science treats through dialectical Gynecological Pain, and meet the Therapeutic Principle of doctor trained in Western medicine, there is obvious effect, remarkable for alleviation pain effect in menstrual period, have nontoxic, non-stimulated, without features such as anaphylaxiss, be applicable to before and after menstrual period or occur hypogastric region spasmic pain between menstrual period, irregular menstrual period, abdominal distention, lumbago also have the symptoms such as general malaise.
In the present invention, preferred scheme is that this comprises following component by weight for the Chinese medicine composition of alleviating pain in menstrual period: 15 parts of Radix Angelicae Sinensis; 10 parts of Herba Leonuris; 20 parts, Flos Carthami; 20 parts of Herba Saussureae Involuerataes; 20 parts of Folium Artemisiae Argyis; 30 parts of Radix Sophorae Flavescentiss; 20 parts of Rhizoma Atractylodis; 15 parts of Radix Rhodiolaes; 22 parts of Fructus Cnidiis; 12 parts of Rhizoma Acori Graminei; 7 parts of Herba Senecionis Scandentiss; 20 parts of Cortex Phellodendris; 30 parts of the Radixs Stemonae; 8 parts of Borneolum Syntheticums; 10 parts of Mentholums.
The preparation method that is used for the Chinese medicine composition of alleviating pain in menstrual period, in turn includes the following steps:
A. weigh the first component according to formula and add in heating tank, then add the first component weight 6-8 distilled water doubly, utilize and be steam heated to 70-90 degree, be then incubated 40-60min; Then be cooled to 40-60 degree, be then incubated 16-18 hour;
Described the first component is Radix Angelicae Sinensis, Herba Saussureae Involueratae, Herba Leonuri, Flos Carthami, Radix Sophorae Flavescentis, Radix Rhodiolae and Rhizoma Acori Graminei;
B. continue to add the second component weighing according to formula in heating tank, and then add second component 6-8 times distilled water, continue to be warming up to 70-90 degree, be then incubated 40-60min; Then be cooled to 40-60 degree;
Described second component is Rhizoma Atractylodis, Fructus Cnidii, Herba Senecionis Scandentis, the Radix Stemonae and Cortex Phellodendri;
C. continue to add the 3rd component weighing according to formula in heating tank, then add the 3rd composition weight 6-8 times distilled water, continue to be warming up to 70-90 degree, then insulation keeps 40-60min, makes elementary medicinal liquid;
Described the 3rd component is Folium Artemisiae Argyi, Borneolum Syntheticum and Mentholum;
D. add 95% ethanol to the elementary medicinal liquid making through c step, then sealing and standing is preserved 72 hours, then removes the medicinal residues in medicinal liquid, obtains medicinal liquid;
The described 95% ethanol volume adding is elementary medicinal liquid 50%;
E. the medicinal liquid obtaining through d step is proceeded in standing tank and leaves standstill 7 days, then proceed in concentration tank and concentrate, obtain concentrated medicament;
The volume of described concentrated medicament is through 10% of the medicine liquid volume of d step acquisition.
In the present invention, preferred preparation method in turn includes the following steps:
A. weigh the first component according to formula and add in heating tank, then add the first component weight 6-8 distilled water doubly, utilize and be steam heated to 90 degree, be then incubated 60min; Then be cooled to 60 degree, be then incubated 18 hours;
Described the first component is Radix Angelicae Sinensis, Herba Saussureae Involueratae, Herba Leonuri, Flos Carthami, Radix Sophorae Flavescentis, Radix Rhodiolae and Rhizoma Acori Graminei,
B. continue to add the second component weighing according to formula in heating tank, and then add second component 6-8 times distilled water, continue to be warming up to 90 degree, be then incubated 1 hour; Then be cooled to 60 degree;
Described second component is Rhizoma Atractylodis, Fructus Cnidii, Herba Senecionis Scandentis, the Radix Stemonae and Cortex Phellodendri;
C. continue to add the 3rd component weighing according to formula in heating tank, then add the 3rd composition weight 6-8 times distilled water, continue to be warming up to 90 degree, then insulation keeps 1 hour, makes elementary medicinal liquid;
Described the 3rd component is Folium Artemisiae Argyi, Borneolum Syntheticum and Mentholum;
D. add 95% ethanol to the elementary medicinal liquid making through c step, then sealing and standing is preserved 72 hours, then removes the medicinal residues in medicinal liquid, obtains medicinal liquid;
The described 95% ethanol volume adding is elementary medicinal liquid 50%;
E. the medicinal liquid obtaining through d step is proceeded in standing tank and leaves standstill 7 days, then proceed in concentration tank and concentrate, obtain concentrated medicament, the volume of described concentrated medicament is through 10% of the medicine liquid volume of d step acquisition.
In this method, successively the first component, the second component and the 3rd component are heated and boiled, can give full play to the activity of medicine, thereby promoted the effect of medicine.
In the present invention, color, abnormal smells from the patient, density that preferred scheme is the concentrated medicament to obtaining through e step detect.
Of the present invention for alleviating the application of Chinese medicine composition of pain in menstrual period, for the preparation of hygienic article, hygienic article is preferably sanitary towel or wet sanitary napkins.Wherein, sanitary towel makes by the following method: the Chinese medicine composition for alleviating pain in menstrual period of 1/6-1/5g is evenly sprayed on to sanitary towel surface, then packs, make product.
Compared with prior art, advantage of the present invention is: the present invention is based on Chinese medicine medical science to Gynecological Pain through aspect pathogenetic understanding and Therapeutic Principle, according to ancient Chinese medicine pharmacy theoretical reference modern pharmacological research, from Chinese medicine material treasure-house, filter out and there is circulation of qi promoting, invigorate blood circulation, regulating menstruation, calm, pain relieving, heat clearing away, removing toxic substances, the natural drug of the effects such as antiinflammatory, combine according to theory of Chinese medical science, each herbal medicine synergism, then by unique preparation method, successively by the first component, the second component and the 3rd component heat and boil, thereby give full play to the activity of medicine, thereby promote the effect of medicine, in medicine of the present invention, each taste is crude drug, meeting the traditional Chinese medical science treats through dialectical Gynecological Pain, and meet the Therapeutic Principle of doctor trained in Western medicine, there is obvious effect, remarkable for alleviation pain effect in menstrual period, have nontoxic, non-stimulated, without features such as anaphylaxiss, be applicable to before and after menstrual period or occur hypogastric region spasmic pain between menstrual period, irregular menstrual period, abdominal distention, lumbago also have the symptoms such as general malaise, Chinese medicine composition of the present invention is widely used, for can be used for the hygienic article such as sanitary towel, wet sanitary napkins.
Below in conjunction with detailed description of the invention, the present invention is described in further detail.
Detailed description of the invention
Embodiment 1
For alleviating a Chinese medicine composition for pain in menstrual period, made by following component by weight: 15 parts of Radix Angelicae Sinensis; 10 parts of Herba Leonuris; 20 parts, Flos Carthami; 20 parts of Herba Saussureae Involuerataes; 20 parts of Folium Artemisiae Argyis; 30 parts of Radix Sophorae Flavescentiss; 20 parts of Rhizoma Atractylodis; 15 parts of Radix Rhodiolaes; 22 parts of Fructus Cnidiis; 12 parts of Rhizoma Acori Graminei; 7 parts of Herba Senecionis Scandentiss; 20 parts of Cortex Phellodendris; 30 parts of the Radixs Stemonae; 8 parts of Borneolum Syntheticums; 10 parts of Mentholums.
Its preparation method in turn includes the following steps as follows:
A. weigh the first component according to formula and add in heating tank, then add the distilled water of 6 times of the first component weight, utilize and be steam heated to 90 degree, be then incubated 60min; Then be cooled to 60 degree, be then incubated 18 hours;
Described the first component is Radix Angelicae Sinensis, Herba Saussureae Involueratae, Herba Leonuri, Flos Carthami, Radix Sophorae Flavescentis, Radix Rhodiolae and Rhizoma Acori Graminei,
B. continue to add the second component weighing according to formula in heating tank, and then add 6 times of distilled water of second component, continue to be warming up to 90 degree, be then incubated 1 hour; Then be cooled to 60 degree;
Described second component is Rhizoma Atractylodis, Fructus Cnidii, Herba Senecionis Scandentis, the Radix Stemonae and Cortex Phellodendri;
C. continue to add the 3rd component weighing according to formula in heating tank, then add 6 times of distilled water of the 3rd composition weight, continue to be warming up to 90 degree, then insulation keeps 1 hour, makes elementary medicinal liquid;
Described the 3rd component is Folium Artemisiae Argyi, Borneolum Syntheticum and Mentholum;
D. add 95% ethanol to the elementary medicinal liquid making through c step, then sealing and standing is preserved 72 hours, then removes the medicinal residues in medicinal liquid, obtains medicinal liquid; The described 95% ethanol volume adding is elementary medicinal liquid 50%;
E. the medicinal liquid obtaining through d step is proceeded in standing tank and leaves standstill 7 days, then proceed in concentration tank and concentrate, obtain concentrated medicament, the volume of described concentrated medicament is through 10% of the medicine liquid volume of d step acquisition.
Embodiment 2
For alleviating a Chinese medicine composition for pain in menstrual period, made by following component by weight: 10 parts of Radix Angelicae Sinensis; 8 parts of Herba Leonuris; 15 parts, Flos Carthami; 15 parts of Herba Saussureae Involuerataes; 15 parts of Folium Artemisiae Argyis; 25 parts of Radix Sophorae Flavescentiss; 15 parts of Rhizoma Atractylodis; 10 parts of Radix Rhodiolaes; 16 parts of Fructus Cnidiis; 10 parts of Rhizoma Acori Graminei; 5 parts of Herba Senecionis Scandentiss; Cortex Phellodendri: 15 parts; 25 parts of the Radixs Stemonae; 6 parts of Borneolum Syntheticums; 8 parts of Mentholums.
Its preparation method in turn includes the following steps as follows:
A. weigh the first component according to formula and add in heating tank, then add the distilled water of 8 times of the first component weight, utilize and be steam heated to 90 degree, be then incubated 1 hour; Then be cooled to 60 degree, be then incubated 18 hours;
Described the first component is Radix Angelicae Sinensis, Herba Saussureae Involueratae, Herba Leonuri, Flos Carthami, Radix Sophorae Flavescentis, Radix Rhodiolae and Rhizoma Acori Graminei,
B. continue to add the second component weighing according to formula in heating tank, and then add 8 times of distilled water of second component, continue to be warming up to 90 degree, be then incubated 1 hour; Then be cooled to 60 degree;
Described second component is Rhizoma Atractylodis, Fructus Cnidii, Herba Senecionis Scandentis, the Radix Stemonae and Cortex Phellodendri;
C. continue to add the 3rd component weighing according to formula in heating tank, then add 8 times of distilled water of the 3rd composition weight, continue to be warming up to 90 degree, then insulation keeps 1 hour, makes elementary medicinal liquid;
Described the 3rd component is Folium Artemisiae Argyi, Borneolum Syntheticum and Mentholum;
D. add 95% ethanol to the elementary medicinal liquid making through c step, then sealing and standing is preserved 72 hours, then removes the medicinal residues in medicinal liquid, obtains medicinal liquid; The described 95% ethanol volume adding is elementary medicinal liquid 50%;
E. the medicinal liquid obtaining through d step is proceeded to and leaves standstill tank standing 7 days, then proceed in concentration tank and concentrate, obtain concentrated medicament, the volume of described concentrated medicament is through 10% of the medicine liquid volume of d step acquisition.
Embodiment 3
For alleviating a Chinese medicine composition for pain in menstrual period, made by following component by weight: 20 parts of Radix Angelicae Sinensis; 12 parts of Herba Leonuris; 25 parts, Flos Carthami; 25 parts of Herba Saussureae Involuerataes; 25 parts of Folium Artemisiae Argyis; 35 parts of Radix Sophorae Flavescentiss; 25 parts of Rhizoma Atractylodis; 20 parts of Radix Rhodiolaes; 28 parts of Fructus Cnidiis; 15 parts of Rhizoma Acori Graminei; 10 parts of Herba Senecionis Scandentiss; Cortex Phellodendri: 25 parts; 35 parts of the Radixs Stemonae; 10 parts of Borneolum Syntheticums; 12 parts of Mentholums.
Its preparation method in turn includes the following steps as follows:
A. weigh the first component according to formula and add in heating tank, then add the distilled water of 7 times of the first component weight, utilize and be steam heated to 70 degree, be then incubated 40min; Then be cooled to 40 degree, be then incubated 16 hours;
Described the first component is Radix Angelicae Sinensis, Herba Saussureae Involueratae, Herba Leonuri, Flos Carthami, Radix Sophorae Flavescentis, Radix Rhodiolae and Rhizoma Acori Graminei,
B. continue to add the second component weighing according to formula in heating tank, and then add 7 times of distilled water of second component, continue to be warming up to 70 degree, be then incubated 40min; Then be cooled to 40 degree;
Described second component is Rhizoma Atractylodis, Fructus Cnidii, Herba Senecionis Scandentis, the Radix Stemonae and Cortex Phellodendri;
C. continue to add the 3rd component weighing according to formula in heating tank, then add 7 times of distilled water of the 3rd composition weight, continue to be warming up to 70 degree, then insulation keeps 40min, makes elementary medicinal liquid;
Described the 3rd component is Folium Artemisiae Argyi, Borneolum Syntheticum and Mentholum;
D. add 95% ethanol to the elementary medicinal liquid making through c step, then sealing and standing is preserved 72 hours, then removes the medicinal residues in medicinal liquid, obtains medicinal liquid; The described 95% ethanol volume adding is elementary medicinal liquid 50%;
E. the medicinal liquid obtaining through d step is proceeded in standing tank and leaves standstill 7 days, then proceed in concentration tank and concentrate, obtain concentrated medicament, the volume of described concentrated medicament is through 10% of the medicine liquid volume of d step acquisition.
Embodiment 4
For alleviating a Chinese medicine composition for pain in menstrual period, made by following component by weight: 15 parts of Radix Angelicae Sinensis; 10 parts of Herba Leonuris; 18 parts, Flos Carthami; 19 parts of Herba Saussureae Involuerataes; 22 parts of Folium Artemisiae Argyis; 28 parts of Radix Sophorae Flavescentiss; 17 parts of Rhizoma Atractylodis; 16 parts of Radix Rhodiolaes; 22 parts of Fructus Cnidiis; 13 parts of Rhizoma Acori Graminei; 8 parts of Herba Senecionis Scandentiss; Cortex Phellodendri: 23 parts; 32 parts of the Radixs Stemonae; 7 parts of Borneolum Syntheticums; 10 parts of Mentholums.
Its preparation method in turn includes the following steps as follows:
A. weigh the first component according to formula and add in heating tank, then add the distilled water of 6.5 times of the first component weight, utilize and be steam heated to 80 degree, be then incubated 50min; Then be cooled to 50 degree, be then incubated 17 hours;
Described the first component is Radix Angelicae Sinensis, Herba Saussureae Involueratae, Herba Leonuri, Flos Carthami, Radix Sophorae Flavescentis, Radix Rhodiolae and Rhizoma Acori Graminei,
B. continue to add the second component weighing according to formula in heating tank, and then add 6.5 times of distilled water of second component, continue to be warming up to 80 degree, be then incubated 50min; Then be cooled to 50 degree;
Described second component is Rhizoma Atractylodis, Fructus Cnidii, Herba Senecionis Scandentis, the Radix Stemonae and Cortex Phellodendri;
C. continue to add the 3rd component weighing according to formula in heating tank, then add 6.5 times of distilled water of the 3rd composition weight, continue to be warming up to 80 degree, then insulation keeps 50min, makes elementary medicinal liquid;
Described the 3rd component is Folium Artemisiae Argyi, Borneolum Syntheticum and Mentholum;
D. add 95% ethanol to the elementary medicinal liquid making through c step, then sealing and standing is preserved 72 hours, then removes the medicinal residues in medicinal liquid, obtains medicinal liquid; The described 95% ethanol volume adding is elementary medicinal liquid 50%;
E. the medicinal liquid obtaining through d step is proceeded to and leaves standstill tank standing 7 days, then proceed in concentration tank and concentrate, obtain concentrated medicament, the volume of described concentrated medicament is through 10% of the medicine liquid volume of d step acquisition.
Comparative example 1
Weigh each component according to the proportioning of embodiment 1, then prepare Chinese medicine composition according to following method:
Weigh each component according to formula and add in heating tank, then add the distilled water of 6 times of component weight, utilize and be steam heated to 90 degree, be then incubated 1 hour; Make elementary medicinal liquid, then add 95% ethanol to elementary medicinal liquid, then sealing and standing is preserved 72 hours, then removes the medicinal residues in medicinal liquid, obtains medicinal liquid; Then medicinal liquid is proceeded to and leave standstill tank standing 7 days, then proceed in concentration tank and concentrate, obtain concentrated medicament, described concentrated.
Comparative example 2
Weigh each component according to the proportioning of embodiment 1, then prepare Chinese medicine composition according to the following method of the method in embodiment 1, difference is: the first component in a step is Rhizoma Atractylodis, Fructus Cnidii, Herba Senecionis Scandentis, Radix Sophorae Flavescentis, the Radix Stemonae and Cortex Phellodendri; The second component in b step is Radix Angelicae Sinensis, Herba Saussureae Involueratae, Herba Leonuri, Flos Carthami, Radix Rhodiolae and Rhizoma Acori Graminei; The 3rd component in c step is Folium Artemisiae Argyi, Borneolum Syntheticum and Mentholum.
Comparative example 3
Weigh each component according to the proportioning of embodiment 1, then prepare Chinese medicine composition according to the following method of the method in embodiment 1, difference is: the first component in a step is Rhizoma Atractylodis, Fructus Cnidii, Herba Leonuri, Radix Sophorae Flavescentis, Flos Carthami, Radix Rhodiolae and Rhizoma Acori Graminei, and the second component in b step is Radix Angelicae Sinensis, Herba Saussureae Involueratae, Herba Senecionis Scandentis, the Radix Stemonae and Cortex Phellodendri; The 3rd component in c step is Folium Artemisiae Argyi, Borneolum Syntheticum and Mentholum.
Comparative example 4
Weigh each component according to the proportioning of embodiment 1, then prepare Chinese medicine composition according to the following method of the method in embodiment 1, difference is: the first component in a step is Folium Artemisiae Argyi, Borneolum Syntheticum, Radix Sophorae Flavescentis, Radix Angelicae Sinensis, Flos Carthami, Radix Rhodiolae and Rhizoma Acori Graminei, and the second component in b step is Rhizoma Atractylodis, Fructus Cnidii, Herba Senecionis Scandentis, the Radix Stemonae and Cortex Phellodendri; The 3rd component in c step is Herba Saussureae Involueratae, Herba Leonuri and Mentholum.
Experimental example 1
Embodiment 1-4, comparative example 1 are made for alleviating the Chinese medicine composition of pain in menstrual period, then, by it is sprayed on sanitary towel surface respectively, every health, through surface sprinkling 0.2g, makes sanitary towel.Then get respectively the sanitary towel that Chinese medicine composition that embodiment 1-4, comparative example 1 make makes, then select 600 menstrual period pain patient, compiling is respectively first group, second group, the 3rd group, the 4th group and the 5th group, every group of corresponding Application Example 1-4, the sanitary towel that comparative example 1 makes respectively, test curative effect, time is 2 months, the results are shown in Table 1:
| ? | First group | Second group | The 3rd group | The 4th group | The 5th group |
| Recovery from illness/people | 70 | 65 | 60 | 61 | 50 |
| Significantly/people | 30 | 30 | 33 | 30 | 28 |
| Effectively/people | 17 | 27 | 22 | 26 | 27 |
| Invalid/people | 3 | 4 | 5 | 3 | 15 |
| Effective percentage | 97％ | 96％ | 95％ | 97％ | 85％ |
Table 1: embodiment 1-4, comparative example 1 test data table
Can find out, the Chinese medicine composition that adopts the present invention to make, its effective percentage is obviously better than the data of comparative example 1, adopts as seen the first component, the second component, the 3rd component to heat successively and boils the drug effect that can give full play to each component, improves the curative effect of medicine.
Model case in embodiment 1 is listed below to table 2:
Model case in table 2: embodiment 1
Experimental example 2
Comparative example 2-4 is made for alleviating the Chinese medicine composition of pain in menstrual period, then, by it is sprayed on sanitary towel surface respectively, every health, through surface sprinkling 0.2g, makes sanitary towel.Then get respectively the sanitary towel that Chinese medicine composition that comparative example 2-4 makes makes, then select 360 menstrual period pain patient, compiling is respectively the 6th group, the 7th group and the 8th group, test curative effect, the time is 2 months, the results are shown in Table 3:
| ? | First group | The 6th group | The 7th group | The 8th group |
| Recovery from illness/people | 70 | 55 | 54 | 54 |
| Significantly/people | 30 | 26 | 25 | 28 |
| Effectively/people | 17 | 7 | 11 | 9 |
| Invalid/people | 3 | 11 | 10 | 9 |
| Effective percentage | 97％ | 89％ | 90％ | 91％ |
Table 3: embodiment 1, comparative example 2-4 test data table
Can find out, the effective percentage of embodiment 1 is obviously better than the data of comparative example 2-4, visible employing the first component, the second component, the 3rd component must heat successively and boil the drug effect that can give full play to each component in strict accordance with component of the present invention, improve the curative effect of medicine.
Above-mentioned embodiment is only the preferred embodiment of the present invention; can not limit the scope of protection of the invention with this, the variation of any unsubstantiality that those skilled in the art does on basis of the present invention and replacement all belong to the present invention's scope required for protection.
Claims (8)
1. for alleviating a Chinese medicine composition for pain in menstrual period, it is characterized in that being made by following component by weight: Radix Angelicae Sinensis 10-20 part; Herba Leonuri 8-12 part; Flos Carthami 15-25 part; Herba Saussureae Involueratae 15-25 part; Folium Artemisiae Argyi 15-25 part; Radix Sophorae Flavescentis 25-35 part; Rhizoma Atractylodis 15-25 part; Radix Rhodiolae 10-20 part; Fructus Cnidii 16-28 part; Rhizoma Acori Graminei 10-15 part; Herba Senecionis Scandentis 5-10 part; Cortex Phellodendri: 15-25 part; Radix Stemonae 25-35 part; Borneolum Syntheticum 6-10 part; Mentholum 8-12 part.
2. according to claim 1 for alleviating the Chinese medicine composition of pain in menstrual period, it is characterized in that being made by following component by weight: 15 parts of Radix Angelicae Sinensis; 10 parts of Herba Leonuris; 20 parts, Flos Carthami; 20 parts of Herba Saussureae Involuerataes; 20 parts of Folium Artemisiae Argyis; 30 parts of Radix Sophorae Flavescentiss; 20 parts of Rhizoma Atractylodis; 15 parts of Radix Rhodiolaes; 22 parts of Fructus Cnidiis; 12 parts of Rhizoma Acori Graminei; 7 parts of Herba Senecionis Scandentiss; 20 parts of Cortex Phellodendris; 30 parts of the Radixs Stemonae; 8 parts of Borneolum Syntheticums; 10 parts of Mentholums.
3. according to claim 1 and 2 for alleviating the preparation method of Chinese medicine composition of pain in menstrual period, it is characterized in that in turn including the following steps:
A. weigh the first component according to formula and add in heating tank, then add the first component weight 6-8 distilled water doubly, utilize and be steam heated to 70-90 degree, be then incubated 40-60min; Then be cooled to 40-60 degree, be then incubated 16-18 hour;
Described the first component is Radix Angelicae Sinensis, Herba Saussureae Involueratae, Herba Leonuri, Flos Carthami, Radix Sophorae Flavescentis, Radix Rhodiolae and Rhizoma Acori Graminei;
B. continue to add the second component weighing according to formula in heating tank, and then add second component 6-8 times distilled water, continue to be warming up to 70-90 degree, be then incubated 40-60min; Then be cooled to 40-60 degree;
Described second component is Rhizoma Atractylodis, Fructus Cnidii, Herba Senecionis Scandentis, the Radix Stemonae and Cortex Phellodendri;
C. continue to add the 3rd component weighing according to formula in heating tank, then add the 3rd composition weight 6-8 times distilled water, continue to be warming up to 70-90 degree, then insulation keeps 40-60min, makes elementary medicinal liquid;
Described the 3rd component is Folium Artemisiae Argyi, Borneolum Syntheticum and Mentholum;
D. add 95% ethanol to the elementary medicinal liquid making through c step, then sealing and standing is preserved 72 hours, then removes the medicinal residues in medicinal liquid, obtains medicinal liquid;
The described 95% ethanol volume adding is elementary medicinal liquid 50%;
E. the medicinal liquid obtaining through d step is proceeded in standing tank and leaves standstill 7 days, then proceed in concentration tank and concentrate, obtain concentrated medicament;
The volume of described concentrated medicament is through 10% of the medicine liquid volume of d step acquisition.
4. according to claim 3 for alleviating the preparation method of Chinese medicine composition of pain in menstrual period, it is characterized in that:
A. weigh the first component according to formula and add in heating tank, then add the first component weight 6-8 distilled water doubly, utilize and be steam heated to 90 degree, be then incubated 60min; Then be cooled to 60 degree, be then incubated 18 hours;
Described the first component is Radix Angelicae Sinensis, Herba Saussureae Involueratae, Herba Leonuri, Flos Carthami, Radix Sophorae Flavescentis, Radix Rhodiolae and Rhizoma Acori Graminei;
B. continue to add the second component weighing according to formula in heating tank, and then add second component 6-8 times distilled water, continue to be warming up to 90 degree, be then incubated 60min; Then be cooled to 60 degree;
Described second component is Rhizoma Atractylodis, Fructus Cnidii, Herba Senecionis Scandentis, the Radix Stemonae and Cortex Phellodendri;
C. continue to add the 3rd component weighing according to formula in heating tank, then add the 3rd composition weight 6-8 times distilled water, continue to be warming up to 90 degree, then insulation keeps 60min, makes elementary medicinal liquid;
Described the 3rd component is Folium Artemisiae Argyi, Borneolum Syntheticum and Mentholum;
D. add 95% ethanol to the elementary medicinal liquid making through c step, then sealing and standing is preserved 72 hours, then removes the medicinal residues in medicinal liquid, obtains medicinal liquid;
The described 95% ethanol volume adding is elementary medicinal liquid 50%;
E. the medicinal liquid obtaining through d step is proceeded in standing tank and leaves standstill 7 days, then proceed in concentration tank and concentrate, obtain concentrated medicament, the volume of described concentrated medicament is through 10% of the medicine liquid volume of d step acquisition.
5. according to claim 3 for alleviating the preparation method of Chinese medicine composition of pain in menstrual period, it is characterized in that: color, abnormal smells from the patient, density to the concentrated medicament obtaining through e step detect.
6. according to claim 1 and 2 for alleviating the application of Chinese medicine composition of pain in menstrual period, it is characterized in that: for the preparation of hygienic article.
7. according to claim 6 for alleviating the application of Chinese medicine composition of pain in menstrual period, it is characterized in that: described hygienic article is sanitary towel or wet sanitary napkins.
8. according to claim 7 for alleviating the application of Chinese medicine composition of pain in menstrual period, it is characterized in that described sanitary towel makes by the following method: the Chinese medicine composition for alleviating pain in menstrual period of 1/6-1/5g is evenly sprayed on to sanitary towel surface, then pack, make product.
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| CN104587521A (en) * | 2015-01-06 | 2015-05-06 | 杭州小姐妹卫生用品有限公司 | Traditional Chinese medicine additive for sanitary towels and preparation method thereof |
| CN105169466A (en) * | 2015-07-22 | 2015-12-23 | 广东妇健企业有限公司 | Traditional Chinese medicinal sanitary towel spray |
| CN105456989A (en) * | 2015-12-14 | 2016-04-06 | 顾璟豪 | Traditional Chinese medicine for eliminating pain and preparation method of traditional Chinese medicine |
| CN106075225A (en) * | 2016-06-24 | 2016-11-09 | 昆明悟真生物科技有限公司 | A kind of Chinese medicine protective pad |
| CN106362190A (en) * | 2016-11-29 | 2017-02-01 | 佛山市秸和科技有限公司 | Multifunctional graphene sanitary towel capable of promoting blood circulation and preparation method thereof |
| CN106729937A (en) * | 2016-12-30 | 2017-05-31 | 福建福布斯国际贸易有限公司 | Plateau Chinese herb medicinal sanitary towel |
| CN107126577A (en) * | 2017-05-11 | 2017-09-05 | 成都欧陌商贸有限责任公司 | The sanitary napkin and preparation method in a kind of maintenance uterus |
| CN107952104A (en) * | 2017-12-04 | 2018-04-24 | 株洲千金药业股份有限公司 | A kind of feminine hygiene articles for preventing menstruation infection and preparation method thereof |
| CN109876051A (en) * | 2019-04-29 | 2019-06-14 | 广东触爱生物医药有限公司 | A kind of gynecological gel and preparation method thereof |
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104147635A (en) * | 2014-08-30 | 2014-11-19 | 湖北蕲艾堂科技有限公司 | Artemisia argyi compound sanitary towel |
| CN104587521A (en) * | 2015-01-06 | 2015-05-06 | 杭州小姐妹卫生用品有限公司 | Traditional Chinese medicine additive for sanitary towels and preparation method thereof |
| CN105169466A (en) * | 2015-07-22 | 2015-12-23 | 广东妇健企业有限公司 | Traditional Chinese medicinal sanitary towel spray |
| CN105456989A (en) * | 2015-12-14 | 2016-04-06 | 顾璟豪 | Traditional Chinese medicine for eliminating pain and preparation method of traditional Chinese medicine |
| CN105456989B (en) * | 2015-12-14 | 2019-12-24 | 顾璟豪 | Chinese medicine for eliminating pain and its preparation method |
| CN106075225A (en) * | 2016-06-24 | 2016-11-09 | 昆明悟真生物科技有限公司 | A kind of Chinese medicine protective pad |
| CN106362190A (en) * | 2016-11-29 | 2017-02-01 | 佛山市秸和科技有限公司 | Multifunctional graphene sanitary towel capable of promoting blood circulation and preparation method thereof |
| CN106729937A (en) * | 2016-12-30 | 2017-05-31 | 福建福布斯国际贸易有限公司 | Plateau Chinese herb medicinal sanitary towel |
| CN107126577A (en) * | 2017-05-11 | 2017-09-05 | 成都欧陌商贸有限责任公司 | The sanitary napkin and preparation method in a kind of maintenance uterus |
| CN107952104A (en) * | 2017-12-04 | 2018-04-24 | 株洲千金药业股份有限公司 | A kind of feminine hygiene articles for preventing menstruation infection and preparation method thereof |
| CN111067975A (en) * | 2018-10-18 | 2020-04-28 | 辽宁泓新科技成果转化服务有限公司 | Gynecological nursing medicine and nursing method |
| CN109876051A (en) * | 2019-04-29 | 2019-06-14 | 广东触爱生物医药有限公司 | A kind of gynecological gel and preparation method thereof |
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